MCID: LTT001
MIFTS: 34

Lattice Corneal Dystrophy malady

Categories: Genetic diseases, Eye diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Lattice Corneal Dystrophy

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Aliases & Descriptions for Lattice Corneal Dystrophy:

Name: Lattice Corneal Dystrophy 10 47 12
Familial Amyloid Neuropathy, Finnish Type 10
 
Familial Amyloid Polyneuropathy, Type V 65

Classifications:



External Ids:

Disease Ontology10 DOID:8943
MeSH36 C537935
UMLS65 C0155127

Summaries for Lattice Corneal Dystrophy

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Wikipedia:68 Lattice corneal dystrophy type, also known as Biber-Haab-Dimmer dystrophy, is a rare form of corneal... more...

MalaCards based summary: Lattice Corneal Dystrophy, also known as familial amyloid neuropathy, finnish type, is related to corneal dystrophy, avellino type and corneal dystrophy, gelatinous drop-like. An important gene associated with Lattice Corneal Dystrophy is TGFBI (Transforming Growth Factor Beta Induced), and among its related pathways are Coregulation of Androgen receptor activity and Senescence and Autophagy. Affiliated tissues include eye, endothelial and brain, and related mouse phenotype cellular.

Related Diseases for Lattice Corneal Dystrophy

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Diseases in the Lattice Corneal Dystrophy family:

Corneal Dystrophy, Lattice Type I Corneal Dystrophy, Lattice Type Iiia
Lattice Corneal Dystrophy Type Ii

Diseases related to Lattice Corneal Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 148)
idRelated DiseaseScoreTop Affiliating Genes
1corneal dystrophy, avellino type33.3TACSTD2, TBCD, TGFBI
2corneal dystrophy, gelatinous drop-like33.1GSN, TACSTD2, TGFBI
3corneal dystrophy, lattice type iiia32.8TBCD, TGFBI, TGIF1
4cervicitis30.3GSN, TACSTD2, TGFBI
5lattice corneal dystrophy type ii12.8
6corneal dystrophy, lattice type i12.3
7amyloidosis, finnish type12.1
8familial amyloidosis, finnish type11.7
9arthritis10.4
10leukemia10.4
11rheumatoid arthritis10.3
12lymphoma10.3
13prostatitis10.3
14endotheliitis10.3
15colorectal cancer10.2
16reticular dysgenesis10.2
17myocardial infarction10.2
18systemic lupus erythematosus10.2
19prostate cancer10.2
20schizencephaly10.2
21hepatocellular carcinoma10.2
22breast cancer10.2
23leprosy10.2
24allergic rhinitis10.2
25multiple myeloma10.2
26mevalonic aciduria10.2
27peutz-jeghers syndrome10.2
28wiskott-aldrich syndrome10.2
29stocco dos santos x-linked mental retardation syndrome10.2
30pelizaeus-merzbacher disease10.2
31adrenoleukodystrophy10.2
32acute leukemia10.2
33acute myocardial infarction10.2
34atherosclerosis10.2
35chronic lymphocytic leukemia10.2
36fecal incontinence10.2
37hematopoietic stem cell transplantation10.2
38hypoplastic left heart syndrome10.2
39mantle cell lymphoma10.2
40polycystic ovary syndrome10.2
41retinal ischemia10.2
42spinal cord injury10.2
43thrombocytopenia10.2
44acute diarrhea10.2
45tuberculous salpingitis10.2
46congenital stationary night blindness10.2
47cervical dystonia10.2
48aphasia10.2
49heavy chain disease10.2
50gamma heavy chain disease10.2

Graphical network of the top 20 diseases related to Lattice Corneal Dystrophy:



Diseases related to lattice corneal dystrophy

Symptoms for Lattice Corneal Dystrophy

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Drugs & Therapeutics for Lattice Corneal Dystrophy

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Lattice Corneal Dystrophy

Genetic Tests for Lattice Corneal Dystrophy

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Anatomical Context for Lattice Corneal Dystrophy

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MalaCards organs/tissues related to Lattice Corneal Dystrophy:

33
Eye, Endothelial, Brain, Breast, Heart, Testes, Tongue

Animal Models for Lattice Corneal Dystrophy or affiliated genes

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MGI Mouse Phenotypes related to Lattice Corneal Dystrophy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.6GSN, TACSTD2, TGFB1, TGFBI, TGIF1

Publications for Lattice Corneal Dystrophy

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Articles related to Lattice Corneal Dystrophy:

(show top 50)    (show all 122)
idTitleAuthorsYear
1
Adaptor protein CRK induces epithelial-mesenchymal transition and metastasis of bladder cancer cells through HGF/c-Met feedback loop. (25816892)
2015
2
Pulmonary arteriovenous malformation with actinomycotic brain abscess: a rare association. (24726259)
2014
3
Clinical and genetic characterization of Bardet-Biedl syndrome in Tunisia: defining a strategy for molecular diagnosis. (23432027)
2013
4
Helicobacter pylori infection in nigerians with dyspepsia. (23966744)
2013
5
Coxsackie and adenovirus receptor (CAR) is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia. (24291282)
2013
6
Safety and effectiveness of adalimumab in Japanese rheumatoid arthritis patients: Postmarketing surveillance report of 7740 patients. (24252049)
2013
7
The tumor-suppressive function of UNC5D and its repressed expression in renal cell carcinoma. (23589179)
2013
8
Vinculin is a dually regulated actin filament barbed end-capping and side-binding protein. (20484056)
2010
9
A Canada-Brazil network in the global eradication of smallpox. (20524373)
2010
10
The role of disordered ribosomal protein extensions in the early steps of eubacterial 50 S ribosomal subunit assembly. (19399222)
2009
11
Duarte (DG) galactosemia: a pilot study of biochemical and neurodevelopmental assessment in children detected by newborn screening. (18976948)
2008
12
Activation of Notch signaling in human colon adenocarcinoma. (19020755)
2008
13
Ischemic stroke as an uncommon complication of Cor triatriatum. (18984443)
2008
14
Selective mutism: a consensus based care pathway of good practice. (18456696)
2008
15
Cardiac allograft vasculopathy: recent developments. (18427143)
2008
16
Effect of folic acid on methotrexate induction of sulfotransferases in rats. (19356074)
2008
17
The effect of environmental and genetic factors in the pathogenesis of periodontitis]. (19127818)
2008
18
HLA class II amino acid epitopes as susceptibility markers of sarcoidosis. (17559577)
2007
19
Phosphorylation-mediated inactivation of coactivator-associated arginine methyltransferase 1. (17640894)
2007
20
Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation. (17211471)
2007
21
Septate uterus with double cervices, unilaterally obstructed vaginal septum, and ipsilateral renal agenesis: a rare combination of mA1llerian and wolffian anomalies complicated by severe endometriosis in an adolescent. (17218245)
2007
22
Recovery of infectious rabbit hemorrhagic disease virus from rabbits after direct inoculation with in vitro-transcribed RNA. (16775346)
2006
23
Emerging evidence for the role of cardiotrophin-1 in cardiac repair in the infarcted heart. (15721858)
2005
24
A case of aorto-right atrial tunnel associated with aortic and tricuspid atresia. (16118896)
2005
25
Antisense inhibition of osteogenic protein 1 disturbs human articular cartilage integrity. (15693015)
2005
26
Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. (15798202)
2005
27
Crossed apraxia of speech: a case report. (15177787)
2004
28
Molecular cloning of the human beta1,4 N- acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain. (14688233)
2003
29
U1 snRNA associates with TFIIH and regulates transcriptional initiation. (12389039)
2002
30
Human chromosome 3: integration of 60 NotI clones into a physical and gene map. (12698000)
2002
31
Post-traumatic plasminogenesis in intraarticular exudate in the knee joint. (12011780)
2002
32
Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes. (11493455)
2001
33
A clinicopathologic reappraisal of brain stem tumor classification. Identification of pilocystic astrocytoma and fibrillary astrocytoma as distinct entities. (11013373)
2000
34
Correlation of serum concentrations of cystatin C and creatinine to inulin clearance in liver cirrhosis. (10794756)
2000
35
Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase. (10383425)
1999
36
Electrogenic Na+/HCO3- cotransporters: cloning and physiology. (10099707)
1999
37
Prolactin response to D-fenfluramine challenge test as a predictor of treatment response to haloperidol in acute schizophrenia. (9542792)
1998
38
C/EBP-epsilon: chromosomal mapping and mutational analysis of the gene in leukemia and preleukemia. (9393598)
1997
39
Recombinant human tumor necrosis factor receptor (p75) Fc fusion protein (TNFR:Fc) in rheumatoid arthritis. (9391689)
1997
40
Extracellular K+ and intracellular pH allosterically regulate renal Kir1.1 channels. (8663367)
1996
41
The protruding scars: keloids and hypertrophic diagnosis and treatment with silicon-gel-sheeting. (7971533)
1994
42
Regulation of C-myc and C-Ha-ras oncogene expression by cell shape. (1385453)
1992
43
Methodology of the National Seroepidemiologic Survey, Mexico]. (1631727)
1992
44
Autoimmune mechanisms in thromboangiitis obliterans (Buerger's disease): the role of tobacco antigen and the major histocompatibility complex. (1598672)
1992
45
Pituitary-gonadal function during sleep in healthy aging men. (1287680)
1992
46
Iliopsoas bursitis: clinical features, radiographic findings, and disease associations. (2218552)
1990
47
Improved brain metabolism with fructose 1-6 diphosphate during insulin-induced hypoglycemic coma. (2719056)
1989
48
Diagnosis and treatment of Prinzmetal's variant angina. (6764160)
1982
49
Oil Aspiration Pneumonia - Adult Type. (21407597)
1939
50

Variations for Lattice Corneal Dystrophy

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Expression for genes affiliated with Lattice Corneal Dystrophy

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Search GEO for disease gene expression data for Lattice Corneal Dystrophy.

Pathways for genes affiliated with Lattice Corneal Dystrophy

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Pathways related to Lattice Corneal Dystrophy according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4GSN, TGIF1
29.2GSN, TGFB1
39.0TGFB1, TGIF1
4
Show member pathways
9.0TGFB1, TGIF1
59.0TGFB1, TGIF1

GO Terms for genes affiliated with Lattice Corneal Dystrophy

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Biological processes related to Lattice Corneal Dystrophy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chondrocyte differentiationGO:00020629.4TGFB1, TGFBI
2transforming growth factor beta receptor signaling pathwayGO:00071799.0TGFB1, TGIF1
3oligodendrocyte developmentGO:00140038.9GSN, TGFB1

Sources for Lattice Corneal Dystrophy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet