MCID: LTT008
MIFTS: 19

Lattice Corneal Dystrophy Type Ii malady

Genetic diseases, Neuronal diseases, Eye diseases, Rare diseases categories

Summaries for Lattice Corneal Dystrophy Type Ii

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34MalaCards
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MalaCards: Lattice Corneal Dystrophy Type Ii, also known as meretoja syndrome, is related to lattice corneal dystrophy and corneal dystrophy. An important gene associated with Lattice Corneal Dystrophy Type Ii is GSN (gelsolin).

Aliases & Classifications for Lattice Corneal Dystrophy Type Ii

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22Genetics Home Reference, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases, Eye diseases


Aliases & Descriptions:

lattice corneal dystrophy type ii 22 63
meretoja syndrome 22 63
amyloid cranial neuropathy with lattice corneal dystrophy 22
amyloidosis, hereditary, transthyretin-related 63
lattice corneal dystrophy, gelsolin type 22
familial amyloid polyneuropathy type iv 22
familial amyloidosis, finnish type 22
amyloidosis due to mutant gelsolin 22
gelsolin-related amyloidosis 22
amyloidosis, meretoja type 22
amyloidosis, finnish type 22
finnish type amyloidosis 63
kymenlaakso syndrome 22
amyloidosis v 22


Related Diseases for Lattice Corneal Dystrophy Type Ii

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18GeneCards, 19GeneDecks
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Diseases in the Lattice Corneal Dystrophy Type 1 family:

Lattice Corneal Dystrophy Lattice Corneal Dystrophy Type 3a
lattice corneal dystrophy type ii

Diseases related to Lattice Corneal Dystrophy Type Ii via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1lattice corneal dystrophy10.8
2corneal dystrophy10.7
3polyneuropathy10.5
4finnish type amyloidosis10.4
5amyloidosis10.4
6cataract10.4
7familial amyloidosis, finnish type10.4
8neuronitis10.2
9hereditary amyloidosis10.2

Graphical network of diseases related to Lattice Corneal Dystrophy Type Ii:



Diseases related to lattice corneal dystrophy type ii

Symptoms for Lattice Corneal Dystrophy Type Ii

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Drugs & Therapeutics for Lattice Corneal Dystrophy Type Ii

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Lattice Corneal Dystrophy Type Ii

Search CenterWatch for Lattice Corneal Dystrophy Type Ii

Genetic Tests for Lattice Corneal Dystrophy Type Ii

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Anatomical Context for Lattice Corneal Dystrophy Type Ii

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Animal Models for Lattice Corneal Dystrophy Type Ii or affiliated genes

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Publications for Lattice Corneal Dystrophy Type Ii

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53PubMed
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Articles related to Lattice Corneal Dystrophy Type Ii:

idTitleAuthorsYear
1
Corneal melt in lattice corneal dystrophy type II after cataract surgery. (19101443)
2009
2
Lattice corneal dystrophy type II: clinical, pathologic, and molecular study in a Spanish family. (17534828)
2007
3
Lattice corneal dystrophy type II associated with familial amyloid polyneuropathy type IV. (8684801)
1996
4
Lattice corneal dystrophy type II with familial amyloid polyneuropathy type IV. (8145387)
1993
5
Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II. (1658654)
1991

Variations for Lattice Corneal Dystrophy Type Ii

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Lattice Corneal Dystrophy Type Ii:

1
id Gene Name Type Significance SNP ID Assembly Location
1GSNNM_001127666.1(GSN): c.520G> A (p.Asp174Asn)single nucleotide variantPathogenicrs121909715GRCh37Chr 9, 124073097: 124073097

Expression for genes affiliated with Lattice Corneal Dystrophy Type Ii

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lattice Corneal Dystrophy Type Ii

Search GEO for disease gene expression data for Lattice Corneal Dystrophy Type Ii.

Pathways for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Compounds for genes affiliated with Lattice Corneal Dystrophy Type Ii

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GO Terms for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Products for genes affiliated with Lattice Corneal Dystrophy Type Ii

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Lattice Corneal Dystrophy Type Ii

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet