MCID: LTT008
MIFTS: 23

Lattice Corneal Dystrophy Type Ii malady

Categories: Genetic diseases, Neuronal diseases, Rare diseases, Eye diseases

Aliases & Classifications for Lattice Corneal Dystrophy Type Ii

About this section

Aliases & Descriptions for Lattice Corneal Dystrophy Type Ii:

Name: Lattice Corneal Dystrophy Type Ii 23 65
Meretoja Syndrome 23 24 65
Amyloid Cranial Neuropathy with Lattice Corneal Dystrophy 23
Familial Amyloid Polyneuropathy, Type Iv 65
Lattice Corneal Dystrophy, Gelsolin Type 23
Familial Amyloid Polyneuropathy Type Iv 23
Familial Amyloidosis, Finnish Type 23
 
Amyloidosis Due to Mutant Gelsolin 23
Gelsolin-Related Amyloidosis 23
Amyloidosis, Meretoja Type 23
Amyloidosis, Finnish Type 23
Kymenlaakso Syndrome 23
Amyloidosis V 23

Classifications:



External Ids:

UMLS65 C1628319, C1622345, C0936273

Summaries for Lattice Corneal Dystrophy Type Ii

About this section
Genetics Home Reference:23 Lattice corneal dystrophy type II is characterized by an accumulation of protein clumps called amyloid deposits in tissues throughout the body. The deposits frequently occur in blood vessel walls and basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Amyloid deposits lead to characteristic signs and symptoms involving the eyes, nerves, and skin that worsen with age.

MalaCards based summary: Lattice Corneal Dystrophy Type Ii, also known as meretoja syndrome, is related to amyloidosis, finnish type and familial amyloidosis, finnish type. An important gene associated with Lattice Corneal Dystrophy Type Ii is GSN (Gelsolin). Affiliated tissues include eye, skin and liver.

Related Diseases for Lattice Corneal Dystrophy Type Ii

About this section

Diseases in the Lattice Corneal Dystrophy family:

Corneal Dystrophy, Lattice Type I Corneal Dystrophy, Lattice Type Iiia
lattice corneal dystrophy type ii

Diseases related to Lattice Corneal Dystrophy Type Ii via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1amyloidosis, finnish type11.8
2familial amyloidosis, finnish type11.7
3lattice corneal dystrophy10.7
4exotropia10.4
5wiskott-aldrich syndrome10.3
6punctate inner choroidopathy10.3
7charge syndrome10.2
8open-angle glaucoma10.2
9labyrinthitis10.2
10neuronitis10.2
11brittle diabetes10.2

Graphical network of diseases related to Lattice Corneal Dystrophy Type Ii:



Diseases related to lattice corneal dystrophy type ii

Symptoms for Lattice Corneal Dystrophy Type Ii

About this section

Drugs & Therapeutics for Lattice Corneal Dystrophy Type Ii

About this section

Drugs for Lattice Corneal Dystrophy Type Ii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Liver Extracts3572

Interventional clinical trials:

idNameStatusNCT IDPhase
1Changes in Body- and Liver-composition During Low Calorie Diet in Morbidly ObeseRecruitingNCT01842425

Search NIH Clinical Center for Lattice Corneal Dystrophy Type Ii

Genetic Tests for Lattice Corneal Dystrophy Type Ii

About this section

Anatomical Context for Lattice Corneal Dystrophy Type Ii

About this section

MalaCards organs/tissues related to Lattice Corneal Dystrophy Type Ii:

33
Eye, Skin, Liver, Breast

Animal Models for Lattice Corneal Dystrophy Type Ii or affiliated genes

About this section

Publications for Lattice Corneal Dystrophy Type Ii

About this section

Articles related to Lattice Corneal Dystrophy Type Ii:

idTitleAuthorsYear
1
Expression of a novel marker, Ubc9, in squamous cell carcinoma of the head and neck. (19309722)
2009
2
Influence of polymorphisms in the factor VII gene promoter on activated factor VII levels and on the risk of myocardial infarction in advanced coronary atherosclerosis. (15351850)
2004
3
The 4-pregnene and 5alpha-pregnane progesterone metabolites formed in nontumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion. (10706108)
2000
4
Fibrinogen-coated albumin microcapsules reduce bleeding in severely thrombocytopenic rabbits. (9883848)
1999
5
Quantitative topographic electrophysiology and functional neurologic status in right middle cerebral artery infarction. (2091715)
1990

Variations for Lattice Corneal Dystrophy Type Ii

About this section

Expression for genes affiliated with Lattice Corneal Dystrophy Type Ii

About this section
Search GEO for disease gene expression data for Lattice Corneal Dystrophy Type Ii.

Pathways for genes affiliated with Lattice Corneal Dystrophy Type Ii

About this section

GO Terms for genes affiliated with Lattice Corneal Dystrophy Type Ii

About this section

Sources for Lattice Corneal Dystrophy Type Ii

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet