MCID: LTT008
MIFTS: 22

Lattice Corneal Dystrophy Type Ii malady

Genetic diseases, Neuronal diseases, Eye diseases, Rare diseases categories

Summaries for Lattice Corneal Dystrophy Type Ii

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Genetics Home Reference:22 Lattice corneal dystrophy type II is characterized by an accumulation of protein clumps called amyloid deposits in tissues throughout the body. The deposits frequently occur in blood vessel walls and basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Amyloid deposits lead to characteristic signs and symptoms involving the eyes, nerves, and skin that worsen with age.

MalaCards based summary: Lattice Corneal Dystrophy Type Ii, also known as amyloid cranial neuropathy with lattice corneal dystrophy, is related to lattice corneal dystrophy and corneal dystrophy. An important gene associated with Lattice Corneal Dystrophy Type Ii is GSN (gelsolin). Affiliated tissues include eye and skin.

Aliases & Classifications for Lattice Corneal Dystrophy Type Ii

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Lattice Corneal Dystrophy Type Ii, Aliases & Descriptions:

Name: Lattice Corneal Dystrophy Type Ii 22 61
Amyloid Cranial Neuropathy with Lattice Corneal Dystrophy 22 61
Familial Amyloid Polyneuropathy Type Iv 22 61
Amyloidosis Due to Mutant Gelsolin 22 61
Gelsolin-Related Amyloidosis 22 61
Kymenlaakso Syndrome 22 61
 
Meretoja Syndrome 22 61
Lattice Corneal Dystrophy, Gelsolin Type 22
Familial Amyloidosis, Finnish Type 22
Amyloidosis, Meretoja Type 22
Amyloidosis, Finnish Type 22
Amyloidosis V 22


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases, Eye diseases


Related Diseases for Lattice Corneal Dystrophy Type Ii

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Diseases in the Lattice Corneal Dystrophy Type 1 family:

Lattice Corneal Dystrophy Lattice Corneal Dystrophy Type 3a
lattice corneal dystrophy type ii

Diseases related to Lattice Corneal Dystrophy Type Ii via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1lattice corneal dystrophy10.8
2corneal dystrophy10.8
3polyneuropathy10.6
4cataract10.4
5finnish type amyloidosis10.4
6amyloidosis10.4
7familial amyloidosis, finnish type10.4
8neuronitis10.2
9hereditary amyloidosis10.2
10neuropathy10.2

Graphical network of diseases related to Lattice Corneal Dystrophy Type Ii:



Diseases related to lattice corneal dystrophy type ii

Symptoms for Lattice Corneal Dystrophy Type Ii

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Drugs & Therapeutics for Lattice Corneal Dystrophy Type Ii

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Drug clinical trials:

Search ClinicalTrials for Lattice Corneal Dystrophy Type Ii

Search NIH Clinical Center for Lattice Corneal Dystrophy Type Ii

Genetic Tests for Lattice Corneal Dystrophy Type Ii

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Anatomical Context for Lattice Corneal Dystrophy Type Ii

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MalaCards organs/tissues related to Lattice Corneal Dystrophy Type Ii:

32
Eye, Skin

Animal Models for Lattice Corneal Dystrophy Type Ii or affiliated genes

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Publications for Lattice Corneal Dystrophy Type Ii

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Articles related to Lattice Corneal Dystrophy Type Ii:

idTitleAuthorsYear
1
Corneal melt in lattice corneal dystrophy type II after cataract surgery. (19101443)
2009
2
Lattice corneal dystrophy type II: clinical, pathologic, and molecular study in a Spanish family. (17534828)
2007
3
Lattice corneal dystrophy type II associated with familial amyloid polyneuropathy type IV. (8684801)
1996
4
Lattice corneal dystrophy type II with familial amyloid polyneuropathy type IV. (8145387)
1993
5
Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II. (1658654)
1991

Variations for Lattice Corneal Dystrophy Type Ii

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Expression for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Expression patterns in normal tissues for genes affiliated with Lattice Corneal Dystrophy Type Ii

Search GEO for disease gene expression data for Lattice Corneal Dystrophy Type Ii.

Pathways for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Compounds for genes affiliated with Lattice Corneal Dystrophy Type Ii

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GO Terms for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Products for genes affiliated with Lattice Corneal Dystrophy Type Ii

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Lattice Corneal Dystrophy Type Ii

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet