MCID: LTT008
MIFTS: 16

Lattice Corneal Dystrophy Type Ii malady

Neuronal diseases, Genetic diseases categories

Summaries for Lattice Corneal Dystrophy Type Ii

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21Genetics Home Reference, 32MalaCards
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Genetics Home Reference:21 Lattice corneal dystrophy type II is characterized by an accumulation of protein clumps called amyloid deposits in tissues throughout the body. The deposits frequently occur in blood vessel walls and basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Amyloid deposits lead to characteristic signs and symptoms involving the eyes, nerves, and skin that worsen with age.

MalaCards: Lattice Corneal Dystrophy Type Ii, also known as meretoja syndrome, is related to lattice corneal dystrophy and corneal dystrophy. An important gene associated with Lattice Corneal Dystrophy Type Ii is GSN (gelsolin). Affiliated tissues include eye and skin.

Aliases & Classifications for Lattice Corneal Dystrophy Type Ii

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60UMLS, 21Genetics Home Reference
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

lattice corneal dystrophy type ii 21 60
meretoja syndrome 21 60
amyloid cranial neuropathy with lattice corneal dystrophy 21
amyloidosis, hereditary, transthyretin-related 60
lattice corneal dystrophy, gelsolin type 21
familial amyloid polyneuropathy type iv 21
amyloidosis due to mutant gelsolin 21
familial amyloidosis, finnish type 21
gelsolin-related amyloidosis 21
amyloidosis, meretoja type 21
amyloidosis, finnish type 21
finnish type amyloidosis 60
kymenlaakso syndrome 21
amyloidosis v 21


Related Diseases for Lattice Corneal Dystrophy Type Ii

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17GeneCards, 18GeneDecks
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Diseases in the Lattice Corneal Dystrophy Type 1 family:

Lattice Corneal Dystrophy Lattice Corneal Dystrophy Type 3a
lattice corneal dystrophy type ii

Diseases related to Lattice Corneal Dystrophy Type Ii via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1lattice corneal dystrophy10.7
2corneal dystrophy10.7
3transthyretin amyloidosis10.6
4familial amyloidosis, finnish type10.5
5polyneuropathy10.5
6familial transthyretin amyloidosis10.4
7finnish type amyloidosis10.4
8amyloidosis10.4
9cataract10.4
10familial amyloid polyneuropathy type 110.3

Graphical network of diseases related to Lattice Corneal Dystrophy Type Ii:



Diseases related to lattice corneal dystrophy type ii

Clinical Features for Lattice Corneal Dystrophy Type Ii

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Drugs & Therapeutics for Lattice Corneal Dystrophy Type Ii

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Lattice Corneal Dystrophy Type Ii

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Anatomical Context for Lattice Corneal Dystrophy Type Ii

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32MalaCards
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MalaCards organs/tissues related to Lattice Corneal Dystrophy Type Ii:

32
Eye, Skin

Animal Models for Lattice Corneal Dystrophy Type Ii or affiliated genes

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Publications for Lattice Corneal Dystrophy Type Ii

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Genetic Variations for Lattice Corneal Dystrophy Type Ii

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Expression for genes affiliated with Lattice Corneal Dystrophy Type Ii

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lattice Corneal Dystrophy Type Ii

Search GEO for disease gene expression data for Lattice Corneal Dystrophy Type Ii.

Pathways for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Compounds for genes affiliated with Lattice Corneal Dystrophy Type Ii

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GO Terms for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Products for genes affiliated with Lattice Corneal Dystrophy Type Ii

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Lattice Corneal Dystrophy Type Ii

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet