MCID: LTT008
MIFTS: 22

Lattice Corneal Dystrophy Type Ii malady

Genetic diseases, Neuronal diseases, Rare diseases, Eye diseases categories

Aliases & Classifications for Lattice Corneal Dystrophy Type Ii

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Aliases & Descriptions for Lattice Corneal Dystrophy Type Ii:

Name: Lattice Corneal Dystrophy Type Ii 23 65
Meretoja Syndrome 23 24 65
Amyloid Cranial Neuropathy with Lattice Corneal Dystrophy 23
Lattice Corneal Dystrophy, Gelsolin Type 23
Familial Amyloid Polyneuropathy Type Iv 23
Amyloidosis Due to Mutant Gelsolin 23
 
Familial Amyloidosis, Finnish Type 23
Gelsolin-Related Amyloidosis 23
Amyloidosis, Meretoja Type 23
Amyloidosis, Finnish Type 23
Kymenlaakso Syndrome 23
Amyloidosis V 23


Classifications:



Summaries for Lattice Corneal Dystrophy Type Ii

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Genetics Home Reference:23 Lattice corneal dystrophy type II is characterized by an accumulation of protein clumps called amyloid deposits in tissues throughout the body. The deposits frequently occur in blood vessel walls and basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Amyloid deposits lead to characteristic signs and symptoms involving the eyes, nerves, and skin that worsen with age.

MalaCards based summary: Lattice Corneal Dystrophy Type Ii, also known as meretoja syndrome, is related to lattice corneal dystrophy and corneal dystrophy. An important gene associated with Lattice Corneal Dystrophy Type Ii is GSN (Gelsolin). Affiliated tissues include eye, skin and liver.

Related Diseases for Lattice Corneal Dystrophy Type Ii

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Diseases in the Lattice Corneal Dystrophy family:

Corneal Dystrophy, Lattice Type I Corneal Dystrophy, Lattice Type Iiia
lattice corneal dystrophy type ii

Diseases related to Lattice Corneal Dystrophy Type Ii via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1lattice corneal dystrophy10.8
2corneal dystrophy10.7
3polyneuropathy10.6
4familial amyloidosis, finnish type10.6
5amyloidosis, finnish type10.4
6cataract10.4
7amyloidosis10.4
8agel amyloidosis10.3
9neuronitis10.3
10hereditary amyloidosis10.3
11neuropathy10.2

Graphical network of diseases related to Lattice Corneal Dystrophy Type Ii:



Diseases related to lattice corneal dystrophy type ii

Symptoms for Lattice Corneal Dystrophy Type Ii

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Drugs & Therapeutics for Lattice Corneal Dystrophy Type Ii

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Changes in Body- and Liver-composition During Low Calorie Diet in Morbidly ObeseRecruitingNCT01842425

Search NIH Clinical Center for Lattice Corneal Dystrophy Type Ii

Genetic Tests for Lattice Corneal Dystrophy Type Ii

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Genetic tests related to Lattice Corneal Dystrophy Type Ii:

id Genetic test Affiliating Genes
1 Meretoja Syndrome24

Anatomical Context for Lattice Corneal Dystrophy Type Ii

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MalaCards organs/tissues related to Lattice Corneal Dystrophy Type Ii:

33
Eye, Skin, Liver

Animal Models for Lattice Corneal Dystrophy Type Ii or affiliated genes

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Publications for Lattice Corneal Dystrophy Type Ii

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Articles related to Lattice Corneal Dystrophy Type Ii:

idTitleAuthorsYear
1
Corneal melt in lattice corneal dystrophy type II after cataract surgery. (19101443)
2009
2
Lattice corneal dystrophy type II: clinical, pathologic, and molecular study in a Spanish family. (17534828)
2007
3
Lattice corneal dystrophy type II associated with familial amyloid polyneuropathy type IV. (8684801)
1996
4
Lattice corneal dystrophy type II with familial amyloid polyneuropathy type IV. (8145387)
1993
5
Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II. (1658654)
1991

Variations for Lattice Corneal Dystrophy Type Ii

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Expression for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Search GEO for disease gene expression data for Lattice Corneal Dystrophy Type Ii.

Pathways for genes affiliated with Lattice Corneal Dystrophy Type Ii

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GO Terms for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Sources for Lattice Corneal Dystrophy Type Ii

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet