MCID: LTT008
MIFTS: 22

Lattice Corneal Dystrophy Type Ii malady

Categories: Genetic diseases, Neuronal diseases, Rare diseases, Eye diseases

Aliases & Classifications for Lattice Corneal Dystrophy Type Ii

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Aliases & Descriptions for Lattice Corneal Dystrophy Type Ii:

Name: Lattice Corneal Dystrophy Type Ii 24 66
Meretoja Syndrome 24 25 66
Amyloid Cranial Neuropathy with Lattice Corneal Dystrophy 24
Familial Amyloid Polyneuropathy, Type Iv 66
Lattice Corneal Dystrophy, Gelsolin Type 24
Familial Amyloid Polyneuropathy Type Iv 24
Amyloidosis Due to Mutant Gelsolin 24
 
Familial Amyloidosis, Finnish Type 24
Gelsolin-Related Amyloidosis 24
Amyloidosis, Meretoja Type 24
Amyloidosis, Finnish Type 24
Kymenlaakso Syndrome 24
Amyloidosis V 24

Classifications:



Summaries for Lattice Corneal Dystrophy Type Ii

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Genetics Home Reference:24 Lattice corneal dystrophy type II is characterized by an accumulation of protein clumps called amyloid deposits in tissues throughout the body. The deposits frequently occur in blood vessel walls and basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Amyloid deposits lead to characteristic signs and symptoms involving the eyes, nerves, and skin that worsen with age.

MalaCards based summary: Lattice Corneal Dystrophy Type Ii, also known as meretoja syndrome, is related to amyloidosis, finnish type and familial amyloidosis, finnish type. An important gene associated with Lattice Corneal Dystrophy Type Ii is GSN (Gelsolin). Affiliated tissues include eye, skin and liver.

Related Diseases for Lattice Corneal Dystrophy Type Ii

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Diseases in the Lattice Corneal Dystrophy family:

Corneal Dystrophy, Lattice Type I Corneal Dystrophy, Lattice Type Iiia
lattice corneal dystrophy type ii

Diseases related to Lattice Corneal Dystrophy Type Ii via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1amyloidosis, finnish type11.3
2familial amyloidosis, finnish type11.3
3lattice corneal dystrophy11.0
4corneal dystrophy10.4
5polyneuropathy10.2
6cataract10.1
7amyloidosis10.1

Graphical network of diseases related to Lattice Corneal Dystrophy Type Ii:



Diseases related to lattice corneal dystrophy type ii

Symptoms for Lattice Corneal Dystrophy Type Ii

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Drugs & Therapeutics for Lattice Corneal Dystrophy Type Ii

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Changes in Body- and Liver-composition During Low Calorie Diet in Morbidly ObeseRecruitingNCT01842425

Search NIH Clinical Center for Lattice Corneal Dystrophy Type Ii

Genetic Tests for Lattice Corneal Dystrophy Type Ii

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Genetic tests related to Lattice Corneal Dystrophy Type Ii:

id Genetic test Affiliating Genes
1 Meretoja Syndrome25

Anatomical Context for Lattice Corneal Dystrophy Type Ii

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MalaCards organs/tissues related to Lattice Corneal Dystrophy Type Ii:

34
Eye, Skin, Liver

Animal Models for Lattice Corneal Dystrophy Type Ii or affiliated genes

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Publications for Lattice Corneal Dystrophy Type Ii

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Articles related to Lattice Corneal Dystrophy Type Ii:

idTitleAuthorsYear
1
Corneal melt in lattice corneal dystrophy type II after cataract surgery. (19101443)
2009
2
Lattice corneal dystrophy type II: clinical, pathologic, and molecular study in a Spanish family. (17534828)
2007
3
Lattice corneal dystrophy type II associated with familial amyloid polyneuropathy type IV. (8684801)
1996
4
Lattice corneal dystrophy type II with familial amyloid polyneuropathy type IV. (8145387)
1993
5
Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II. (1658654)
1991

Variations for Lattice Corneal Dystrophy Type Ii

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Expression for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Search GEO for disease gene expression data for Lattice Corneal Dystrophy Type Ii.

Pathways for genes affiliated with Lattice Corneal Dystrophy Type Ii

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GO Terms for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Sources for Lattice Corneal Dystrophy Type Ii

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet