MCID: LTT008
MIFTS: 21

Lattice Corneal Dystrophy Type Ii malady

Genetic diseases, Neuronal diseases, Rare diseases, Eye diseases categories

Summaries for Lattice Corneal Dystrophy Type Ii

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Genetics Home Reference:21 Lattice corneal dystrophy type II is characterized by an accumulation of protein clumps called amyloid deposits in tissues throughout the body. The deposits frequently occur in blood vessel walls and basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Amyloid deposits lead to characteristic signs and symptoms involving the eyes, nerves, and skin that worsen with age.

MalaCards based summary: Lattice Corneal Dystrophy Type Ii, also known as meretoja syndrome, is related to amyloidosis, finnish type and lattice corneal dystrophy. An important gene associated with Lattice Corneal Dystrophy Type Ii is GSN (gelsolin). Affiliated tissues include eye and skin.

Aliases & Classifications for Lattice Corneal Dystrophy Type Ii

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Lattice Corneal Dystrophy Type Ii, Aliases & Descriptions:

Name: Lattice Corneal Dystrophy Type Ii 21 60
Meretoja Syndrome 21 22 60
Amyloid Cranial Neuropathy with Lattice Corneal Dystrophy 21
Lattice Corneal Dystrophy, Gelsolin Type 21
Familial Amyloid Polyneuropathy Type Iv 21
Familial Amyloidosis, Finnish Type 21
 
Amyloidosis Due to Mutant Gelsolin 21
Gelsolin-Related Amyloidosis 21
Amyloidosis, Meretoja Type 21
Amyloidosis, Finnish Type 21
Kymenlaakso Syndrome 21
Amyloidosis V 21


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases, Eye diseases


Related Diseases for Lattice Corneal Dystrophy Type Ii

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Diseases in the Lattice Corneal Dystrophy family:

Corneal Dystrophy, Lattice Type I Corneal Dystrophy, Lattice Type Iiia
lattice corneal dystrophy type ii

Diseases related to Lattice Corneal Dystrophy Type Ii via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1amyloidosis, finnish type10.8
2lattice corneal dystrophy10.8
3corneal dystrophy10.8
4polyneuropathy10.6
5familial amyloidosis, finnish type10.6
6cataract10.4
7amyloidosis10.4
8neuronitis10.2
9hereditary amyloidosis10.2
10neuropathy10.2

Graphical network of diseases related to Lattice Corneal Dystrophy Type Ii:



Diseases related to lattice corneal dystrophy type ii

Symptoms for Lattice Corneal Dystrophy Type Ii

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Drugs & Therapeutics for Lattice Corneal Dystrophy Type Ii

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Drug clinical trials:

Search ClinicalTrials for Lattice Corneal Dystrophy Type Ii

Search NIH Clinical Center for Lattice Corneal Dystrophy Type Ii

Genetic Tests for Lattice Corneal Dystrophy Type Ii

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Genetic tests related to Lattice Corneal Dystrophy Type Ii:

id Genetic test Affiliating Genes
1 Meretoja Syndrome22

Anatomical Context for Lattice Corneal Dystrophy Type Ii

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MalaCards organs/tissues related to Lattice Corneal Dystrophy Type Ii:

31
Eye, Skin

Animal Models for Lattice Corneal Dystrophy Type Ii or affiliated genes

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Publications for Lattice Corneal Dystrophy Type Ii

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Articles related to Lattice Corneal Dystrophy Type Ii:

idTitleAuthorsYear
1
Corneal melt in lattice corneal dystrophy type II after cataract surgery. (19101443)
2009
2
Lattice corneal dystrophy type II: clinical, pathologic, and molecular study in a Spanish family. (17534828)
2007
3
Lattice corneal dystrophy type II associated with familial amyloid polyneuropathy type IV. (8684801)
1996
4
Lattice corneal dystrophy type II with familial amyloid polyneuropathy type IV. (8145387)
1993
5
Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II. (1658654)
1991

Variations for Lattice Corneal Dystrophy Type Ii

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Expression for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Search GEO for disease gene expression data for Lattice Corneal Dystrophy Type Ii.

Pathways for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Compounds for genes affiliated with Lattice Corneal Dystrophy Type Ii

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GO Terms for genes affiliated with Lattice Corneal Dystrophy Type Ii

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Products for genes affiliated with Lattice Corneal Dystrophy Type Ii

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Lattice Corneal Dystrophy Type Ii

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet