MCID: LFT009
MIFTS: 44

Left Ventricular Outflow Tract Obstruction malady

Category: Genetic diseases (common)

Aliases & Classifications for Left Ventricular Outflow Tract Obstruction

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Aliases & Descriptions for Left Ventricular Outflow Tract Obstruction:

Name: Left Ventricular Outflow Tract Obstruction 24 26
Hypoplastic Left Heart 24 26
Hypoplastic Left Heart Syndrome 67
Interupted Aortic Arch Type a 24
Coarctation of the Aorta 24
Aortic Valve Disease 2 67
 
Aortic Valve Stenosis 67
Bicuspid Aortic Valve 24
Aortic Valve Disorder 67
Aortic Valve Disease 24
Aortic Stenosis 24

Classifications:



Summaries for Left Ventricular Outflow Tract Obstruction

About this section
MalaCards based summary: Left Ventricular Outflow Tract Obstruction, also known as hypoplastic left heart, is related to supravalvar aortic stenosis and aortic valve disease 2. An important gene associated with Left Ventricular Outflow Tract Obstruction is NOTCH1 (Notch 1), and among its related pathways are Dorso-ventral axis formation and Cell adhesion_ECM remodeling. The drug alprostadil has been mentioned in the context of this disorder. Affiliated tissues include heart, lung and liver, and related mouse phenotypes are craniofacial and cardiovascular system.

Related Diseases for Left Ventricular Outflow Tract Obstruction

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Diseases related to Left Ventricular Outflow Tract Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1supravalvar aortic stenosis12.5
2aortic valve disease 212.4
3aortic valve disease 112.4
4familial bicuspid aortic valve12.3
5patent ductus arteriosus and bicuspid aortic valve with hand anomalies12.2
6cor triatriatum11.3
7aortic valve insufficiency11.3
8congenital heart defects, nonsyndromic, 211.2
9mitochondrial complex v deficiency, mitochondrial 111.2
10mitochondrial complex v deficiency, mitochondrial 211.2
11aortic coarctation11.1
12congenital heart defects, hamartomas of tongue, and polysyndactyly11.0
13mucopolysaccharidosis is10.9
14cardiomyopathy10.9
15transposition of the great arteries10.7
16ventricular septal defect10.6
17myocardial infarction10.5
18accessory mitral valve tissue10.4
19prp systemic amyloidosis10.4MT-ATP6, MT-ATP8
20cardiogenic shock10.4
21le marec bracq picaud syndrome10.4MT-ATP6, MT-ATP8
22acute myocardial infarction10.3
23atrioventricular septal defect10.3
24syncope10.3
25right aortic arch10.3
26ischemia10.2
27aneurysm10.2
28pheochromocytoma10.1
29heart disease10.1
30amyloidosis10.1
31hallux varus and preaxial polysyndactyly10.1ERBB4, NOTCH1
32rheumatic disease10.1
33atrioventricular block10.0
34sarcoma10.0
35hypertensive heart disease10.0
36stress cardiomyopathy10.0
37coronary artery disease9.9
38renal cell carcinoma9.9
39fabry disease9.9
40ebstein anomaly9.9
41pulmonary atresia with intact ventricular septum9.9
42hemolytic anemia9.9
43hypoplastic left heart syndrome9.9
44artery disease9.9
45infective endocarditis9.9
46endocarditis9.9
47hemiplegia9.9
48pericardial effusion9.9
49mitral valve stenosis9.9
50adenocarcinoma9.9

Comorbidity relations with Left Ventricular Outflow Tract Obstruction via Phenotypic Disease Network (PDN):

(show top 50)    (show all 68)
Acquired ThrombocytopeniaAcute Myocardial Infarction
Aortic Valve Disease 2Aortic Valve Insufficiency
Aplastic AnemiaBenign Essential Hypertension
Coronary Artery DiseaseDeficiency Anemia
Disseminated Intravascular CoagulationDressler's Syndrome
GoutHemopericardium
Hypertension, EssentialHypothyroidism
Intermediate Coronary SyndromeIron Deficiency Anemia
Ischemic Heart DiseaseActive Peptic Ulcer Disease
Acute CystitisAcute Kidney Failure
Aortic AneurysmAortic Atherosclerosis
AphasiaAtrioventricular Block
Basilar Artery InsufficiencyBronchitis
Cardiogenic ShockCerebral Atherosclerosis
Chronic Kidney FailureCongenital Aortic Valve Insufficiency
Decubitus UlcerDental Caries
EsophagitisFamilial Atrial Fibrillation
First-Degree Atrioventricular BlockGastritis
Generalized AtherosclerosisHeart Conduction Disease
Heart DiseaseHereditary Ataxia
Idiopathic Interstitial PneumoniaIntracranial Embolism
Left Bundle Branch HemiblockMarfan Syndrome
Mesenteric Artery IschemiaMobitz Type Ii Atrioventricular Block
Nutmeg LiverOsteoporosis
Peripheral Vascular DiseasePostinflammatory Pulmonary Fibrosis

Graphical network of the top 20 diseases related to Left Ventricular Outflow Tract Obstruction:



Diseases related to left ventricular outflow tract obstruction

Symptoms for Left Ventricular Outflow Tract Obstruction

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Drugs & Therapeutics for Left Ventricular Outflow Tract Obstruction

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Drugs for Left Ventricular Outflow Tract Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dopamineapproved375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
2
Ethanolapproved204364-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
3
Bupropionapproved31934841-39-9, 34911-55-2444
Synonyms:
( -)-2-(tert-Butylamino)-3'-chloropropiophenone
( -)-2-(tert-Butylamino)-3'-chlorpropiophenon
(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
(+-)-Bupropion
.alpha.-(tert-Butylamino)-m-chloropropiophenone
1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one
2-(Tert-Butylamino)-3'-chloropropiophenone
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
34841-36-6 (hydrochloride)
34841-39-9
34911-55-2
AB00053756
AC-197
AC1L198Y
AMFEBUTAMONE HCl
Amfebutamon
Amfebutamona
Amfebutamona [INN-Spanish]
Amfebutamone
Amfebutamonum
Amfebutamonum [INN-Latin]
BPBio1_000042
BRD-A05186015-003-05-7
BRN 2101062
BSPBio_000038
BSPBio_002247
Bupropion (INN)
Bupropion (Old RN)
Bupropion (USAN)
Bupropion Hcl
Bupropion SR
Bupropion [INN:BAN]
Bupropion hydrocloride
C06860
CHEBI:3219
CHEMBL894
CID444
CPD000472526
D07591
DB01156
DivK1c_007050
Elont
 
HMS2051G10
HMS2089G14
Jsp006301
KBio1_001994
KBio2_002143
KBio2_004711
KBio2_007279
KBio3_001467
KBioGR_001168
KBioSS_002143
L000725
LS-122817
Lopac0_000166
MLS001424015
MolPort-003-845-432
NCGC00015122-06
NCGC00089751-02
NCI60_002714
NSC315851
Prestwick0_000249
Prestwick1_000249
Prestwick2_000249
Prestwick3_000249
SAM001246699
SMR000472526
SPBio_001817
SPBio_002257
SpecPlus_000954
Spectrum2_001659
Spectrum3_000644
Spectrum4_000614
Spectrum5_001406
Spectrum_001663
TL8002604
UNII-01ZG3TPX31
Wellbatrin
Wellbutrin
Wellbutrin SR
Wellbutrin XL
Zyban
alpha-(tert-butylamino)-m-chloropropiophenone
amfebutamonum
bupropion
4
Caffeineapproved, Nutraceutical38058-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethyl-2,6-dioxopurine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert-Pep
Alert-pep
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine (USP)
Caffeine (natural)
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffeinum
Caffine
Cafipel
Caféine
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
DivK1c_000730
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Hycomine
Hycomine Compound
I14-4386
 
IDI1_000730
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Snapback Stimulant Powders
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stim
Synalgos-Dc
TNP00310
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
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5Vitamins5095
6Psychotropic Drugs6279
7Neurotransmitter Agents17734
8Neurotransmitter Uptake Inhibitors3464
9Dopamine Uptake Inhibitors1305
10Dopamine Agents3759
11Antidepressive Agents, Second-Generation1287
12Antidepressive Agents2666
13Antidepressive Agents, Tricyclic293
14Cytochrome P-450 CYP2D6 Inhibitors716
15Cytochrome P-450 Enzyme Inhibitors3822
16Immunoglobulins6045
17Antibodies6045
18Kavanutraceutical1489000-38-8

Interventional clinical trials:

(show all 12)
idNameStatusNCT IDPhase
1A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract ObstructionRecruitingNCT02842242Phase 2
2Hypertrophic Cardiomyopathy Symptom Release by BX1514MRecruitingNCT02590809Phase 2
3NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve ImplantationNot yet recruitingNCT03015194Phase 2
4Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung DiseaseUnknown statusNCT00830726
5Right Ventricular Outflow Tract StudyCompletedNCT01294839
6Long-Term Results of DDD Pacing in Obstructive Hypertrophic CardiomyopathyCompletedNCT00001530
7Bupropion & Cardio Birth Defect (Slone)CompletedNCT01597661
8Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDYRecruitingNCT01614717
9Multi Modal Cardiac Imaging Prior Transcatheter Aortic Valve ImplantationRecruitingNCT01805739
10Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency DepartmentRecruitingNCT02781207
11Pilot Trial: Comparison of Flow PatternsRecruitingNCT02288871
12Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart SyndromeActive, not recruitingNCT01135485

Search NIH Clinical Center for Left Ventricular Outflow Tract Obstruction

Inferred drug relations via UMLS67/NDF-RT45:

Genetic Tests for Left Ventricular Outflow Tract Obstruction

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Genetic tests related to Left Ventricular Outflow Tract Obstruction:

id Genetic test Affiliating Genes
1 Left Ventricular Outflow Tract Obstruction (lvoto)26 24 NOTCH1
2 Hypoplastic Left Heart26

Anatomical Context for Left Ventricular Outflow Tract Obstruction

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MalaCards organs/tissues related to Left Ventricular Outflow Tract Obstruction:

35
Heart, Lung, Liver, Testes

Animal Models for Left Ventricular Outflow Tract Obstruction or affiliated genes

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MGI Mouse Phenotypes related to Left Ventricular Outflow Tract Obstruction:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.9EGFR, ERBB4, NOTCH1, VEGFA
2MP:00053858.4EGFR, ERBB4, NOTCH1, TAB2, VEGFA
3MP:00053808.4EGFR, ERBB4, NOTCH1, TAB2, VEGFA
4MP:00107718.3EGFR, ERBB4, NOTCH1, TAB2, VEGFA
5MP:00053708.2EGFR, NOTCH1, TAB2, VEGFA

Publications for Left Ventricular Outflow Tract Obstruction

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Articles related to Left Ventricular Outflow Tract Obstruction:

(show top 50)    (show all 483)
idTitleAuthorsYear
1
Late Left Ventricular Outflow Tract Obstruction Following the Rastelli Operation: Expectations Out to 20 Years. (27587496)
2016
2
Influence of apical position on the left ventricular outflow tract obstruction in congenitally corrected transposition. (27842759)
2016
3
Left Ventricular Outflow Tract Obstruction: Coarctation of the Aorta, Interrupted Aortic Arch, and Borderline Left Ventricle. (27490616)
2016
4
Intentional Laceration of the Anterior Mitral Valve Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter MitralA Valve Replacement: Pre-Clinical Findings. (27609260)
2016
5
Surgical Ventricular Septal Myectomy for Patients With Noonan Syndrome and Symptomatic Left Ventricular Outflow Tract Obstruction. (26272816)
2015
6
Hybrid Stage I Palliation in a 1.1 kg, 28-Week Preterm Neonate With Posterior Malalignment Ventricular Septal Defect, Left Ventricular Outflow Tract Obstruction, and Coarctation of the Aorta. (25324263)
2014
7
Robot-assisted septal myectomy for hypertrophic cardiomyopathy with left ventricular outflow tract obstruction. (24793596)
2014
8
Left ventricular outflow tract obstruction following an uncomplicated primary percutaneous coronary intervention: a recognized but rare cause of cardiogenic shock. (24062935)
2013
9
A very unusual cause of mechanical left ventricular outflow tract obstruction. (23533200)
2013
10
Cardiogenic shock due to dynamic left ventricular outflow tract obstruction in acute myocardial infarction. (21452037)
2011
11
Left ventricular outflow tract obstruction after the modified single patch repair of atrioventricular septal defects: teasing fact from fiction. (20338382)
2010
12
Arterial switch and modified Konno procedure with detachment of the aortic root for transposition of the great arteries and left ventricular outflow tract obstruction. (20667390)
2010
13
Accessory mitral valve causing left ventricular outflow tract obstruction. (20719735)
2010
14
Syncope from dynamic left ventricular outflow tract obstruction simulating hypertrophic cardiomyopathy in a patient with primary AL-type amyloid heart disease. (19436787)
2009
15
Abnormal papillary muscle morphology is independently associated with increased left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. (17690158)
2008
16
Left ventricular rhabdomyoma with severe left ventricular outflow tract obstruction: development of delayed hemiplegia after cardiopulmonary bypass. (17803580)
2007
17
Takotsubo cardiomyopathy with left ventricular outflow tract obstruction. (16337511)
2006
18
Different effects of propranolol, phenylephrine, and saline volume loading on catecholamine-induced left ventricular outflow tract obstruction in acute coronary syndrome. (16607055)
2006
19
Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy. (16754630)
2006
20
Modified Nikaidoh procedure for transposition of great arteries, ventricular septal defect and left ventricular outflow tract obstruction. (17151976)
2006
21
Long-term results of apical aortic conduits in children with complex left ventricular outflow tract obstruction. (16305893)
2005
22
Multiple causes of left ventricular outflow tract obstruction in a 58-year-old woman. (15901301)
2005
23
Catecholamine therapy inducing dynamic left ventricular outflow tract obstruction. (15882688)
2005
24
Inferior myocardial infarction and shock associated with left ventricular outflow tract obstruction. (15322669)
2004
25
Hypovolemia-induced reversible severe mitral regurgitation due to left ventricular outflow tract obstruction. (12487637)
2002
26
Apico-aortic conduits in children with severe left ventricular outflow tract obstruction. (11834067)
2002
27
Left ventricular outflow tract obstruction after myocardial infarction due to a hyperdynamic basal septum. (11415498)
2001
28
Dynamic left ventricular outflow tract obstruction: an unusual mechanism mimicking anterior myocardial infarction with cardiogenic shock. (11214704)
2001
29
Comparison of left ventricular outflow tract obstruction in interruption of the aortic arch and in coarctation of the aorta, with diagnostic, developmental, and surgical implications. (11024401)
2000
30
Left ventricular outflow tract obstruction due to valve myxoma. (10881855)
2000
31
Potential mechanism of left ventricular outflow tract obstruction after mitral ring annuloplasty. (10047649)
1999
32
Dynamic left ventricular outflow tract obstruction in a patient with pheochromocytoma. (10737567)
1999
33
Patch repair of subsemilunar conal septal defect resulting in severe left ventricular outflow tract obstruction. (9359571)
1997
34
Influence of right ventricular pacing site on left ventricular outflow tract obstruction in patients with hypertrophic obstructive cardiomyopathy. (8609346)
1996
35
Left ventricular outflow tract obstruction as a cause for hypotension and symptoms during dobutamine stress echocardiography. (8674261)
1996
36
Relief of complex left ventricular outflow tract obstruction with pulmonary autografts. (7739236)
1995
37
Reversible steroid-induced hypertrophic cardiomyopathy with left ventricular outflow tract obstruction in two newborns. (7575834)
1995
38
Left ventricular outflow tract obstruction defined by active three-dimensional echocardiography using rotational transthoracic acquisition. (10150630)
1994
39
Reduction of the left-ventricular outflow-tract obstruction by aortoventriculoplasty--long-term results of 96 patients. (8211925)
1993
40
Increased left ventricular outflow tract obstruction during exercise in patients with hypertrophic cardiomyopathy. (8426026)
1993
41
Left ventricular outflow tract obstruction with aortic arch anomalies and ventricular septal defect. (2241361)
1990
42
Accessory mitral valve leaflet causing aortic regurgitation and left ventricular outflow tract obstruction. Case report and review of published reports. (3285879)
1988
43
Double outlet right ventricle with severe left ventricular outflow tract obstruction due to small ventricular septal defect and anomalous adherence of the mitral valve to the ventricular septum. (3437510)
1987
44
Left ventricular outflow tract obstruction with mitral valve replacement in small ventricular cavities. (3942435)
1986
45
Left ventricular outflow tract obstruction related to a valve prosthesis: case caused by a low-profile mitral prosthesis. (3974300)
1985
46
Dynamic left ventricular outflow tract obstruction associated with pheochromocytoma. (7196146)
1981
47
Cross-sectional echocardiographic localization of sites of left ventricular outflow tract obstruction. (942808)
1976
48
Left ventricular outflow-tract obstruction with an ostium primum defect. Report of two cases. (5437896)
1970
49
Roentgenographic aspects of congenital left ventricular outflow tract obstruction. (5844924)
1965
50
ANGIOCARDIOGRAPHIC FINDINGS IN IDIOPATHIC MYOCARDIAL HYPERTROPHY WITH RIGHT AND LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION. (14258277)
1965

Variations for Left Ventricular Outflow Tract Obstruction

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Expression for genes affiliated with Left Ventricular Outflow Tract Obstruction

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Search GEO for disease gene expression data for Left Ventricular Outflow Tract Obstruction.

Pathways for genes affiliated with Left Ventricular Outflow Tract Obstruction

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GO Terms for genes affiliated with Left Ventricular Outflow Tract Obstruction

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Cellular components related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial proton-transporting ATP synthase complexGO:00057539.7MT-ATP6, MT-ATP8
2receptor complexGO:00432359.0EGFR, ERBB4, NOTCH1

Biological processes related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1ATP biosynthetic processGO:000675410.2MT-ATP6, MT-ATP8
2mitochondrial ATP synthesis coupled proton transportGO:004277610.1MT-ATP6, MT-ATP8
3cell fate commitmentGO:004516510.1ERBB4, NOTCH1
4positive regulation of cardiac muscle cell proliferationGO:006004510.0ERBB4, NOTCH1
5response to hyperoxiaGO:005509310.0MT-ATP6, MT-ATP8
6coronary artery morphogenesisGO:00609829.9NOTCH1, VEGFA
7cardiac vascular smooth muscle cell developmentGO:00609489.9NOTCH1, VEGFA
8positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:00614199.9NOTCH1, VEGFA
9coronary vein morphogenesisGO:00031699.9NOTCH1, VEGFA
10branching morphogenesis of an epithelial tubeGO:00487549.8NOTCH1, VEGFA
11ERBB2 signaling pathwayGO:00381289.8EGFR, ERBB4
12tube formationGO:00351489.7NOTCH1, VEGFA
13regulation of cell motilityGO:20001459.5EGFR, ERBB4
14cellular response to vascular endothelial growth factor stimulusGO:00359249.5NOTCH1, VEGFA
15mammary gland alveolus developmentGO:00607499.4ERBB4, VEGFA
16positive regulation of MAP kinase activityGO:00434069.4EGFR, VEGFA
17lactationGO:00075959.4ERBB4, VEGFA
18lung developmentGO:00303249.1EGFR, NOTCH1, VEGFA
19positive regulation of epithelial cell proliferationGO:00506799.1EGFR, NOTCH1, VEGFA
20heart developmentGO:00075079.0ERBB4, NOTCH1, TAB2
21positive regulation of neuroblast proliferationGO:00020529.0NOTCH1, VEGFA
22positive regulation of protein phosphorylationGO:00019348.9EGFR, ERBB4, VEGFA
23positive regulation of cell migrationGO:00303358.7EGFR, NOTCH1, VEGFA
24positive regulation of cell proliferationGO:00082848.1EGFR, ERBB4, NOTCH1, VEGFA

Molecular functions related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hydrogen ion transmembrane transporter activityGO:00150789.9MT-ATP6, MT-ATP8
2transmembrane transporter activityGO:00228579.8MT-ATP6, MT-ATP8
3phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:00469349.3EGFR, ERBB4
4transmembrane receptor protein tyrosine kinase activityGO:00047149.3EGFR, ERBB4

Sources for Left Ventricular Outflow Tract Obstruction

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet