MCID: LFT009
MIFTS: 42

Left Ventricular Outflow Tract Obstruction malady

Category: Genetic diseases (common)

Aliases & Classifications for Left Ventricular Outflow Tract Obstruction

About this section

Aliases & Descriptions for Left Ventricular Outflow Tract Obstruction:

Name: Left Ventricular Outflow Tract Obstruction 22 24
Hypoplastic Left Heart Syndrome 65
Interupted Aortic Arch Type a 22
Coarctation of the Aorta 22
Hypoplastic Left Heart 22
Aortic Valve Disease 2 65
 
Aortic Valve Disorder 65
Bicuspid Aortic Valve 22
Aortic Valve Stenosis 65
Aortic Valve Disease 22
Aortic Stenosis 22

Classifications:



External Ids:

UMLS65 C3542024

Summaries for Left Ventricular Outflow Tract Obstruction

About this section
MalaCards based summary: Left Ventricular Outflow Tract Obstruction, also known as hypoplastic left heart syndrome, is related to hypoplastic left heart syndrome and hypoplastic left heart syndrome 2. An important gene associated with Left Ventricular Outflow Tract Obstruction is NOTCH1 (Notch 1), and among its related pathways are Dorso-ventral axis formation and Nuclear signaling by ERBB4. The drug alprostadil has been mentioned in the context of this disorder. Affiliated tissues include heart, lung and brain, and related mouse phenotypes are liver/biliary system and embryo.

Related Diseases for Left Ventricular Outflow Tract Obstruction

About this section

Diseases related to Left Ventricular Outflow Tract Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 370)
idRelated DiseaseScoreTop Affiliating Genes
1hypoplastic left heart syndrome13.0
2hypoplastic left heart syndrome 212.9
3hypoplastic left heart syndrome 112.8
4supravalvar aortic stenosis12.8
5patent ductus arteriosus-bicuspid aortic valve-hand anomalies syndrome12.7
6familial bicuspid aortic valve12.7
7subvalvular aortic stenosis12.5
8aortic valve disease 212.1
9williams-beuren syndrome11.9
10aortic coarctation11.6
11aortic valve disease 111.5
12kashani strom utley syndrome11.4
13lymphoma10.7
14congenital heart defects, nonsyndromic, 210.7
15mitochondrial complex v deficiency, mitochondrial 110.7
16mitochondrial complex v deficiency, mitochondrial 210.7
17leukemia10.7
18hepatitis10.6
19prostatitis10.6
20breast cancer10.6
21ritscher-schinzel syndrome10.6
22infertility10.5
23congenital heart defects, hamartomas of tongue, and polysyndactyly10.5
24cor triatriatum10.5
25myocardial infarction10.5
26hepatocellular carcinoma10.5
27melanoma10.5
28cervicitis10.5
29adenocarcinoma10.5
30ischemia10.5
31pancreatitis10.5
32thyroiditis10.5
33neuronitis10.5
34endotheliitis10.5
35nephronophthisis 1610.4
36congenital heart defects, multiple types, 410.4
37heterotaxy, visceral, 1, x-linked10.4
38hyperlipidemia type 310.4
39schizophrenia10.4
40neuroblastoma10.4
41coronary artery disease10.4
42obesity10.4
43insulin-like growth factor i10.4
44pancreatic cancer10.4
45pulmonary hypertension10.4
46acute myocardial infarction10.4
47arthritis10.4
48atherosclerosis10.4
49mantle cell lymphoma10.4
50artery disease10.4

Graphical network of the top 20 diseases related to Left Ventricular Outflow Tract Obstruction:



Diseases related to left ventricular outflow tract obstruction

Symptoms for Left Ventricular Outflow Tract Obstruction

About this section

Drugs & Therapeutics for Left Ventricular Outflow Tract Obstruction

About this section

Drugs for Left Ventricular Outflow Tract Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dopamineapproved308462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
2
Bupropionapproved30834841-39-9444
Synonyms:
( -)-2-(tert-Butylamino)-3'-chloropropiophenone
( -)-2-(tert-Butylamino)-3'-chlorpropiophenon
(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
(+-)-Bupropion
.alpha.-(tert-Butylamino)-m-chloropropiophenone
1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one
2-(Tert-Butylamino)-3'-chloropropiophenone
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
34841-36-6 (hydrochloride)
34841-39-9
34911-55-2
AB00053756
AC-197
AC1L198Y
AMFEBUTAMONE HCl
Amfebutamon
Amfebutamona
Amfebutamona [INN-Spanish]
Amfebutamone
Amfebutamonum
Amfebutamonum [INN-Latin]
Aplenzin
BPBio1_000042
BRD-A05186015-003-05-7
BRN 2101062
BSPBio_000038
BSPBio_002247
Budeprion
Buproban
Bupropion
Bupropion (INN)
Bupropion (Old RN)
Bupropion (USAN)
Bupropion Hcl
Bupropion Hydrochloride
Bupropion SR
Bupropion [INN:BAN]
Bupropion hydrocloride
C06860
CHEBI:3219
CHEMBL894
CID444
CPD000472526
D07591
DB01156
 
DivK1c_007050
Elont
HMS2051G10
HMS2089G14
Jsp006301
KBio1_001994
KBio2_002143
KBio2_004711
KBio2_007279
KBio3_001467
KBioGR_001168
KBioSS_002143
L000725
LS-122817
Lopac0_000166
MLS001424015
MolPort-003-845-432
NCGC00015122-06
NCGC00089751-02
NCI60_002714
NSC315851
Prestwick0_000249
Prestwick1_000249
Prestwick2_000249
Prestwick3_000249
SAM001246699
SMR000472526
SPBio_001817
SPBio_002257
SpecPlus_000954
Spectrum2_001659
Spectrum3_000644
Spectrum4_000614
Spectrum5_001406
Spectrum_001663
TL8002604
UNII-01ZG3TPX31
Wellbatrin
Wellbutrin
Wellbutrin SR
Wellbutrin XL
Wellbutrin Xl
Zyban
alpha-(tert-butylamino)-m-chloropropiophenone
amfebutamonum
bupropion
3
Caffeineapproved, Nutraceutical33958-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert
Alert-Pep
Alert-pep
Allertness Aid
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
Awake
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine
Caffeine (USP)
Caffeine (natural)
Caffeine Citrate
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine citrate
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffine
Cafipel
Caféine
Circle K Nosnooze
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
Conrx Alert
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
Diurex Ultra
Diurex WaterCaps
DivK1c_000730
Drowz Away Maximum strength
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Equaline Stay Awake
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Good Neighbor Pharmacy Stay Awake
Good Sense Stay Awake
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Health Mart Stay Awake
Healthy Accents Stay Awake
Hycomine
Hycomine Compound
I14-4386
IDI1_000730
 
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Leader Alertness Aid
Lil Drug Store Nosnooze
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Caffeine
Maximum Strength Snapback Stimulant Powders
Maximum Strength Stay Awake
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Nano Ppc
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Pep-back Peak Performance
Pep-back Ultra
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Smart Sense Stay Awake
Sohmed Alertness Aid
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stay Alert Aid
Stay Awake
Stay Awake Maximum Strength
Stay Awake Maximum strength
Stim
Sunmark Stay Awake
Synalgos-Dc
TNP00310
Teina
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Topcare Stay Awake maximum strength
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
4Vitamins3857
5
6Neurotransmitter Agents14795
7Neurotransmitter Uptake Inhibitors2857
8Dopamine Uptake Inhibitors925
9Psychotropic Drugs5501
10Dopamine Agents3084
11Antidepressive Agents, Second-Generation1087
12Antidepressive Agents2367
13Antidepressive Agents, Tricyclic250
14Cytochrome P-450 CYP2D6 Inhibitors602
15Cytochrome P-450 Enzyme Inhibitors3036
16Immunoglobulins4477
17Antibodies4477
18Kavanutraceutical1329000-38-85281052

Interventional clinical trials:

idNameStatusNCT IDPhase
1Hypertrophic Cardiomyopathy Symptom Release by BX1514MRecruitingNCT02590809Phase 2
2Bupropion & Cardio Birth Defect (Slone)CompletedNCT01597661
3Long-Term Results of DDD Pacing in Obstructive Hypertrophic CardiomyopathyCompletedNCT00001530
4Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDYRecruitingNCT01614717
5Multi Modal Cardiac Imaging Prior Transcatheter Aortic Valve ImplantationRecruitingNCT01805739
6Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency DepartmentRecruitingNCT02781207
7Pilot Trial: Comparison of Flow PatternsRecruitingNCT02288871
8Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung DiseaseRecruitingNCT00830726
9Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart SyndromeActive, not recruitingNCT01135485
10Right Ventricular Outflow Tract StudyActive, not recruitingNCT01294839

Search NIH Clinical Center for Left Ventricular Outflow Tract Obstruction

Inferred drug relations via UMLS65/NDF-RT43:

Genetic Tests for Left Ventricular Outflow Tract Obstruction

About this section

Genetic tests related to Left Ventricular Outflow Tract Obstruction:

id Genetic test Affiliating Genes
1 Left Ventricular Outflow Tract Obstruction (lvoto)22 NOTCH1

Anatomical Context for Left Ventricular Outflow Tract Obstruction

About this section

MalaCards organs/tissues related to Left Ventricular Outflow Tract Obstruction:

33
Heart, Lung, Brain, Bone, Prostate, Colon, Breast

Animal Models for Left Ventricular Outflow Tract Obstruction or affiliated genes

About this section

MGI Mouse Phenotypes related to Left Ventricular Outflow Tract Obstruction:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.4EGFR, NOTCH1, TAB2, VEGFA
2MP:00053807.9EGFR, ERBB4, NOTCH1, TAB2, VEGFA
3MP:00053827.8EGFR, ERBB4, NOTCH1, VEGFA
4MP:00107717.7EGFR, ERBB4, NOTCH1, TAB2, VEGFA
5MP:00053857.6EGFR, ERBB4, NOTCH1, TAB2, VEGFA

Publications for Left Ventricular Outflow Tract Obstruction

About this section

Articles related to Left Ventricular Outflow Tract Obstruction:

(show top 50)    (show all 441)
idTitleAuthorsYear
1
The expression of Toll-like receptors 2, 4 and 9 in kidneys of patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. (24773611)
2014
2
European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in Leukemia. (24323983)
2013
3
Dysmegakaryocytopoiesis and maintaining platelet count in patients with plasma cell neoplasm. (23814762)
2013
4
Network-based differential gene expression analysis suggests cell cycle related genes regulated by E2F1 underlie the molecular difference between smoker and non-smoker lung adenocarcinoma. (24341432)
2013
5
Early prediction of cerebral palsy after neonatal intensive care using motor development trajectories in infancy. (23856349)
2013
6
Therapeutic strategies in psoriasis patients with psoriatic arthritis: focus on new agents. (23580094)
2013
7
Therapeutic effect of low-molecular weight heparin and incidence of lower limb deep venous thrombosis and pulmonary embolism after laparoscopic bariatric surgery. (24300923)
2013
8
Self-reported memory impairment and brain PET of amyloid and tau in middle-aged and older adults without dementia. (22335970)
2012
9
Does advanced-stage endometriosis affect the gene expression of estrogen and progesterone receptors in granulosa cells? (21269613)
2011
10
Benign fibrous histiocytoma of the skin metastasizing to the inguinal lymph node. (22102079)
2011
11
A novel L218P mutation in NADH-cytochrome b5 reductase associated with type I recessive congenital methemoglobinemia. (19579085)
2009
12
Mechanistic basis for the emergence of catalytic competence against carbapenem antibiotics by the GES family of beta-lactamases. (19656947)
2009
13
Influence that oscillating positive expiratory pressure using predetermined expiratory pressures has on the viscosity and transportability of sputum in patients with bronchiectasis. (20126920)
2009
14
Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue. (17899366)
2008
15
Reduced habituation of trigeminal reflexes in patients with episodic cluster headache during cluster period. (18624808)
2008
16
Histopathological response of transitional cell carcinoma to arsenic trioxide during the treatment of concurrently diagnosed acute promyelocytic leukaemia. (18995171)
2008
17
Adenovirus E4orf6 assembles with Cullin5-ElonginB-ElonginC E3 ubiquitin ligase through an HIV/SIV Vif-like BC-box to regulate p53. (17351129)
2007
18
The ERK 1 and 2 pathway in the nervous system: from basic aspects to possible clinical applications in pain and visceral dysfunction. (19305741)
2007
19
Methylprednisolone pulse therapy for severe immune thrombocytopenia associated with infectious mononucleosis. (17160996)
2007
20
Genetic polymorphisms of the novel FCERIA gene region: relation to total serum IgE levels. (17521040)
2007
21
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. (17463248)
2007
22
Analysis of antitumor activity elicited by vaccination with combinations of interleukin-12 DNA with gp100 DNA or the chemokine CCL21 in vivo. (16942445)
2006
23
The relationship between legal status, perceived pressure and motivation in treatment for drug dependence: results from a European study of Quasi-Compulsory Treatment. (16968995)
2006
24
Involvement of cytoskeletal proteins and growth factor receptors during development of the human eye. (16586110)
2006
25
Erythropoietin in heart failure and other cardiovascular diseases: hematopoietic and pleiotropic effects. (16248829)
2005
26
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. (15548201)
2004
27
Treatment of chronic cough in children with montelukast,a leukotriene receptor antagonist. (15584630)
2004
28
HER2/neu overexpression in the development of muscle-invasive transitional cell carcinoma of the bladder. (14520464)
2003
29
Association of homozygous deletion of the Humhv3005 and the VH3-30.3 genes with renal involvement in systemic lupus erythematosus. (12765304)
2003
30
Expression of WASP and Scar1/WAVE1 actin-associated proteins is differentially modulated during differentiation of HL-60 cells. (12601690)
2003
31
p63 expression in normal skin and usual cutaneous carcinomas. (12358808)
2002
32
Soluble interleukin-2 receptor in SjAPgren's syndrome: relation to main serum immunological and immunohistochemical parameters. (11642512)
2001
33
Decreased tolerance to interleukin-2 with repeated courses of therapy in patients with metastatic melanoma or renal cell cancer. (10838668)
2000
34
The relationship between coagulation time and bilateral occurrence in chronic subdural hematoma]. (10363267)
1999
35
A role for the vesicle tethering protein, p115, in the post-mitotic stacking of reassembling Golgi cisternae in a cell-free system. (10402460)
1999
36
Effect of sphingomyelin and its metabolites on the activity of human recombinant PLC delta 1. (9251249)
1997
37
Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women. (9394686)
1997
38
Complex formation between p53 and replication protein A inhibits the sequence-specific DNA binding of p53 and is regulated by single-stranded DNA. (9121469)
1997
39
Expression of interleukin-1 receptor antagonist protein in post-mortem human brain tissues of Alzheimer's disease and control cases. (9113207)
1997
40
Elevation of circulating proadrenomedullin-N terminal 20-peptide in thyrotoxicosis. (9156034)
1997
41
Multiple splicing variants of the estrogen receptor are present in individual human breast tumors. (9010317)
1996
42
Morphine receptors in immunocytes and neurons. (7952830)
1994
43
Peliosis hepatis. An unusual case involving the spleen and lymph nodes. (2741700)
1989
44
Angiomyoma of the palate. (6783578)
1980
45
The fine structure of a prolactin-rich pituitary chromophobe adenoma (a case report). (977384)
1976
46
The effect of protein deficiency on the resistance of rats to infection with spirochetes of relapsing fever. (14832488)
1951
47
B. pyocyaneus corneal ulcer treated with penicillin. (18872482)
1948
48
YAWS. (21772572)
1928
49
50

Variations for Left Ventricular Outflow Tract Obstruction

About this section

Expression for genes affiliated with Left Ventricular Outflow Tract Obstruction

About this section
Search GEO for disease gene expression data for Left Ventricular Outflow Tract Obstruction.

Pathways for genes affiliated with Left Ventricular Outflow Tract Obstruction

About this section

GO Terms for genes affiliated with Left Ventricular Outflow Tract Obstruction

About this section

Biological processes related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1mitochondrial ATP synthesis coupled proton transportGO:004277610.3MT-ATP6, MT-ATP8
2ATP synthesis coupled proton transportGO:00159869.9MT-ATP6, MT-ATP8
3regulation of cell migrationGO:00303349.8ERBB4, NOTCH1
4cell fate commitmentGO:00451659.8ERBB4, NOTCH1
5regulation of cell motilityGO:20001459.8EGFR, ERBB4
6coronary vein morphogenesisGO:00031699.7NOTCH1, VEGFA
7cardiac vascular smooth muscle cell developmentGO:00609489.7NOTCH1, VEGFA
8positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:00614199.7NOTCH1, VEGFA
9peptidyl-tyrosine phosphorylationGO:00181089.7EGFR, ERBB4
10transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.7EGFR, ERBB4
11coronary artery morphogenesisGO:00609829.7NOTCH1, VEGFA
12epidermis developmentGO:00085449.6EGFR, NOTCH1
13positive regulation of epithelial cell proliferationGO:00506799.5EGFR, VEGFA
14branching morphogenesis of an epithelial tubeGO:00487549.5NOTCH1, VEGFA
15mammary gland alveolus developmentGO:00607499.4ERBB4, VEGFA
16positive regulation of neuroblast proliferationGO:00020529.3NOTCH1, VEGFA
17lung developmentGO:00303249.0NOTCH1, VEGFA
18positive regulation of cell migrationGO:00303358.9EGFR, NOTCH1, VEGFA
19vascular endothelial growth factor receptor signaling pathwayGO:00480108.4EGFR, ERBB4, VEGFA

Molecular functions related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor signaling protein tyrosine kinase activityGO:00047169.6EGFR, ERBB4
2ATPase activityGO:00168879.6MT-ATP6, MT-ATP8

Sources for Left Ventricular Outflow Tract Obstruction

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet