MCID: LFT009
MIFTS: 46

Left Ventricular Outflow Tract Obstruction malady

Category: Genetic diseases (common)

Aliases & Classifications for Left Ventricular Outflow Tract Obstruction

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Aliases & Descriptions for Left Ventricular Outflow Tract Obstruction:

Name: Left Ventricular Outflow Tract Obstruction 22 24
Hypoplastic Left Heart Syndrome 65
Interupted Aortic Arch Type a 22
Coarctation of the Aorta 22
Hypoplastic Left Heart 22
Aortic Valve Disease 2 65
 
Aortic Valve Disorder 65
Bicuspid Aortic Valve 22
Aortic Valve Stenosis 65
Aortic Valve Disease 22
Aortic Stenosis 22

Classifications:



External Ids:

UMLS65 C3542024

Summaries for Left Ventricular Outflow Tract Obstruction

About this section
MalaCards based summary: Left Ventricular Outflow Tract Obstruction, also known as hypoplastic left heart syndrome, is related to supravalvar aortic stenosis and aortic valve disease 2. An important gene associated with Left Ventricular Outflow Tract Obstruction is NOTCH1 (Notch 1), and among its related pathways are Dorso-ventral axis formation and Nuclear signaling by ERBB4. The drug alprostadil has been mentioned in the context of this disorder. Affiliated tissues include heart, prostate and t cells, and related mouse phenotypes are liver/biliary system and embryo.

Related Diseases for Left Ventricular Outflow Tract Obstruction

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Diseases related to Left Ventricular Outflow Tract Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1supravalvar aortic stenosis12.5
2aortic valve disease 212.4
3aortic valve disease 112.4
4familial bicuspid aortic valve12.4
5patent ductus arteriosus-bicuspid aortic valve-hand anomalies syndrome12.3
6aortic coarctation11.2
7cardiomyopathy10.9
8hypertrophic cardiomyopathy10.9
9transposition of the great arteries10.8
10ventricular septal defect10.8
11aortic valve insufficiency10.7
12cor triatriatum10.7
13myocardial infarction10.6
14accessory mitral valve tissue10.6
15cardiogenic shock10.5
16intellectual disability-coarse face-macrocephaly-cerebellar hypotrophy syndrome10.5MT-ATP6, MT-ATP8
17acute myocardial infarction10.5
18mitochondrial disease with severe hypotonia, lactic acidaemia and hyperammonemia10.4MT-ATP6, MT-ATP8
19atrioventricular septal defect10.4
20syncope10.4
21right aortic arch10.4
22alcoholic cardiomyopathy10.3MT-ATP6, MT-ATP8
23ischemia10.3
24aneurysm10.3
25congenital heart defects, nonsyndromic, 210.3
26mitochondrial complex v deficiency, mitochondrial 110.3
27mitochondrial complex v deficiency, mitochondrial 210.3
28pheochromocytoma10.2
29heart disease10.2
30amyloidosis10.2
31rheumatic disease10.2
32hypotrichosis10.2ERBB4, NOTCH1
33atrioventricular block10.2
34sarcoma10.2
35hypertensive heart disease10.2
36stress cardiomyopathy10.2
37mucopolysaccharidosis is10.0
38coronary artery disease10.0
39renal cell carcinoma10.0
40fabry disease10.0
41hemolytic anemia10.0
42hypoplastic left heart syndrome10.0
43artery disease10.0
44infective endocarditis10.0
45endocarditis10.0
46hemiplegia10.0
47pericardial effusion10.0
48ebstein anomaly10.0
49mitral valve stenosis10.0
50adenocarcinoma10.0

Comorbidity relations with Left Ventricular Outflow Tract Obstruction via Phenotypic Disease Network (PDN):

(show top 50)    (show all 72)
Acquired ThrombocytopeniaAcute Myocardial Infarction
Aortic Valve Disease 2Aortic Valve Insufficiency
Aplastic AnemiaBenign Essential Hypertension
Coronary Artery DiseaseDeficiency Anemia
Disseminated Intravascular CoagulationDressler's Syndrome
GoutHemopericardium
Hypertension, EssentialHypothyroidism
Intermediate Coronary SyndromeIron Deficiency Anemia
Ischemic Heart DiseaseActive Peptic Ulcer Disease
Acute CystitisAcute Kidney Failure
Aortic AneurysmAortic Atherosclerosis
AphasiaAtrioventricular Block
Basilar Artery InsufficiencyBronchitis
Cardiogenic ShockCerebral Atherosclerosis
Cerebrovascular DiseaseChronic Kidney Failure
Congenital Aortic Valve InsufficiencyDecubitus Ulcer
Dental CariesEsophagitis
Familial Atrial FibrillationFirst-Degree Atrioventricular Block
GastritisGeneralized Atherosclerosis
Heart Conduction DiseaseHeart Disease
Hereditary AtaxiaHypertrophic Cardiomyopathy
Idiopathic Interstitial PneumoniaIntracranial Embolism
Left Bundle Branch HemiblockMarfan Syndrome
Mesenteric Artery IschemiaMobitz Type Ii Atrioventricular Block
Nutmeg LiverOsteoporosis

Graphical network of the top 20 diseases related to Left Ventricular Outflow Tract Obstruction:



Diseases related to left ventricular outflow tract obstruction

Symptoms for Left Ventricular Outflow Tract Obstruction

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Drugs & Therapeutics for Left Ventricular Outflow Tract Obstruction

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Drugs for Left Ventricular Outflow Tract Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dopamineapproved308462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
2
Bupropionapproved30834841-39-9444
Synonyms:
( -)-2-(tert-Butylamino)-3'-chloropropiophenone
( -)-2-(tert-Butylamino)-3'-chlorpropiophenon
(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
(+-)-Bupropion
.alpha.-(tert-Butylamino)-m-chloropropiophenone
1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one
2-(Tert-Butylamino)-3'-chloropropiophenone
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
34841-36-6 (hydrochloride)
34841-39-9
34911-55-2
AB00053756
AC-197
AC1L198Y
AMFEBUTAMONE HCl
Amfebutamon
Amfebutamona
Amfebutamona [INN-Spanish]
Amfebutamone
Amfebutamonum
Amfebutamonum [INN-Latin]
Aplenzin
BPBio1_000042
BRD-A05186015-003-05-7
BRN 2101062
BSPBio_000038
BSPBio_002247
Budeprion
Buproban
Bupropion
Bupropion (INN)
Bupropion (Old RN)
Bupropion (USAN)
Bupropion Hcl
Bupropion Hydrochloride
Bupropion SR
Bupropion [INN:BAN]
Bupropion hydrocloride
C06860
CHEBI:3219
CHEMBL894
CID444
CPD000472526
D07591
DB01156
 
DivK1c_007050
Elont
HMS2051G10
HMS2089G14
Jsp006301
KBio1_001994
KBio2_002143
KBio2_004711
KBio2_007279
KBio3_001467
KBioGR_001168
KBioSS_002143
L000725
LS-122817
Lopac0_000166
MLS001424015
MolPort-003-845-432
NCGC00015122-06
NCGC00089751-02
NCI60_002714
NSC315851
Prestwick0_000249
Prestwick1_000249
Prestwick2_000249
Prestwick3_000249
SAM001246699
SMR000472526
SPBio_001817
SPBio_002257
SpecPlus_000954
Spectrum2_001659
Spectrum3_000644
Spectrum4_000614
Spectrum5_001406
Spectrum_001663
TL8002604
UNII-01ZG3TPX31
Wellbatrin
Wellbutrin
Wellbutrin SR
Wellbutrin XL
Wellbutrin Xl
Zyban
alpha-(tert-butylamino)-m-chloropropiophenone
amfebutamonum
bupropion
3
Caffeineapproved, Nutraceutical33958-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert
Alert-Pep
Alert-pep
Allertness Aid
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
Awake
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine
Caffeine (USP)
Caffeine (natural)
Caffeine Citrate
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine citrate
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffine
Cafipel
Caféine
Circle K Nosnooze
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
Conrx Alert
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
Diurex Ultra
Diurex WaterCaps
DivK1c_000730
Drowz Away Maximum strength
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Equaline Stay Awake
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Good Neighbor Pharmacy Stay Awake
Good Sense Stay Awake
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Health Mart Stay Awake
Healthy Accents Stay Awake
Hycomine
Hycomine Compound
I14-4386
IDI1_000730
 
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Leader Alertness Aid
Lil Drug Store Nosnooze
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Caffeine
Maximum Strength Snapback Stimulant Powders
Maximum Strength Stay Awake
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Nano Ppc
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Pep-back Peak Performance
Pep-back Ultra
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Smart Sense Stay Awake
Sohmed Alertness Aid
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stay Alert Aid
Stay Awake
Stay Awake Maximum Strength
Stay Awake Maximum strength
Stim
Sunmark Stay Awake
Synalgos-Dc
TNP00310
Teina
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Topcare Stay Awake maximum strength
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
4Vitamins3857
5
6Neurotransmitter Agents14795
7Neurotransmitter Uptake Inhibitors2857
8Dopamine Uptake Inhibitors925
9Psychotropic Drugs5501
10Dopamine Agents3084
11Antidepressive Agents, Second-Generation1087
12Antidepressive Agents2367
13Antidepressive Agents, Tricyclic250
14Cytochrome P-450 CYP2D6 Inhibitors602
15Cytochrome P-450 Enzyme Inhibitors3036
16Immunoglobulins4477
17Antibodies4477
18Kavanutraceutical1329000-38-85281052

Interventional clinical trials:

idNameStatusNCT IDPhase
1Hypertrophic Cardiomyopathy Symptom Release by BX1514MRecruitingNCT02590809Phase 2
2Bupropion & Cardio Birth Defect (Slone)CompletedNCT01597661
3Long-Term Results of DDD Pacing in Obstructive Hypertrophic CardiomyopathyCompletedNCT00001530
4Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDYRecruitingNCT01614717
5Multi Modal Cardiac Imaging Prior Transcatheter Aortic Valve ImplantationRecruitingNCT01805739
6Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency DepartmentRecruitingNCT02781207
7Pilot Trial: Comparison of Flow PatternsRecruitingNCT02288871
8Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung DiseaseRecruitingNCT00830726
9Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart SyndromeActive, not recruitingNCT01135485
10Right Ventricular Outflow Tract StudyActive, not recruitingNCT01294839

Search NIH Clinical Center for Left Ventricular Outflow Tract Obstruction

Inferred drug relations via UMLS65/NDF-RT43:

Genetic Tests for Left Ventricular Outflow Tract Obstruction

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Genetic tests related to Left Ventricular Outflow Tract Obstruction:

id Genetic test Affiliating Genes
1 Left Ventricular Outflow Tract Obstruction (lvoto)22 NOTCH1

Anatomical Context for Left Ventricular Outflow Tract Obstruction

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MalaCards organs/tissues related to Left Ventricular Outflow Tract Obstruction:

33
Heart, Prostate, T cells, Lung, Brain, Liver, Breast

Animal Models for Left Ventricular Outflow Tract Obstruction or affiliated genes

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MGI Mouse Phenotypes related to Left Ventricular Outflow Tract Obstruction:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.4EGFR, NOTCH1, TAB2, VEGFA
2MP:00053807.9EGFR, ERBB4, NOTCH1, TAB2, VEGFA
3MP:00053827.8EGFR, ERBB4, NOTCH1, VEGFA
4MP:00107717.7EGFR, ERBB4, NOTCH1, TAB2, VEGFA
5MP:00053857.6EGFR, ERBB4, NOTCH1, TAB2, VEGFA

Publications for Left Ventricular Outflow Tract Obstruction

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Articles related to Left Ventricular Outflow Tract Obstruction:

(show top 50)    (show all 462)
idTitleAuthorsYear
1
Current mid-term outcome with an integrated surgical strategy for correction of d-transposition of the great arteries with ventricular septal defect and left ventricular outflow tract obstruction. (27009103)
2016
2
Left ventricular outflow tract obstruction in ICU patients. (27054628)
2016
3
Surgical Ventricular Septal Myectomy for Patients With Noonan Syndrome and Symptomatic Left Ventricular Outflow Tract Obstruction. (26272816)
2015
4
Hybrid Stage I Palliation in a 1.1 kg, 28-Week Preterm Neonate With Posterior Malalignment Ventricular Septal Defect, Left Ventricular Outflow Tract Obstruction, and Coarctation of the Aorta. (25324263)
2014
5
Robot-assisted septal myectomy for hypertrophic cardiomyopathy with left ventricular outflow tract obstruction. (24793596)
2014
6
Impact of incidental amyloidosis on the prognosis of patients with hypertrophic cardiomyopathy undergoing septal myectomy for left ventricular outflow tract obstruction. (25217455)
2014
7
Relation between left ventricular outflow tract obstruction and left ventricular shape in patients with hypertrophic cardiomyopathy: a cardiac magnetic resonance imaging study. (23906680)
2013
8
The role of alcohol septal ablation in the treatment of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. (22093511)
2011
9
Exercise-induced left ventricular outflow tract obstruction in symptomatic patients with Anderson-Fabry disease. (21700093)
2011
10
Cardiogenic shock due to dynamic left ventricular outflow tract obstruction in acute myocardial infarction. (21452037)
2011
11
Haemodynamic effects of acute intravenous metoprolol in apical ballooning syndrome with dynamic left ventricular outflow tract obstruction. (20097684)
2010
12
Surgical management of left ventricular outflow tract obstruction after biventricular repair of double outlet right ventricle. (20191035)
2010
13
Left ventricular outflow tract obstruction after the modified single patch repair of atrioventricular septal defects: teasing fact from fiction. (20338382)
2010
14
Mutations in VEGFA are associated with congenital left ventricular outflow tract obstruction. (20420808)
2010
15
The optimal procedure for the great arteries and left ventricular outflow tract obstruction. An anatomical study. (17353131)
2007
16
Left ventricular rhabdomyoma with severe left ventricular outflow tract obstruction: development of delayed hemiplegia after cardiopulmonary bypass. (17803580)
2007
17
Takotsubo cardiomyopathy with left ventricular outflow tract obstruction. (16337511)
2006
18
Different effects of propranolol, phenylephrine, and saline volume loading on catecholamine-induced left ventricular outflow tract obstruction in acute coronary syndrome. (16607055)
2006
19
Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy. (16754630)
2006
20
Long-term results of apical aortic conduits in children with complex left ventricular outflow tract obstruction. (16305893)
2005
21
Multiple causes of left ventricular outflow tract obstruction in a 58-year-old woman. (15901301)
2005
22
Repair of transposition of the great arteries, ventricular septal defect and left ventricular outflow tract obstruction. (15082275)
2004
23
Patients with mild hypertensive heart disease and left ventricular outflow tract obstruction: treatment with angiotensin II antagonists. (15372301)
2004
24
Inferior myocardial infarction and shock associated with left ventricular outflow tract obstruction. (15322669)
2004
25
Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. (12540642)
2003
26
Echocardiographic diagnosis of left ventricular outflow tract obstruction after mitral valve replacement with subvalvular preservation. (12414054)
2002
27
Hypovolemia-induced reversible severe mitral regurgitation due to left ventricular outflow tract obstruction. (12487637)
2002
28
Comparison of left ventricular outflow tract obstruction in interruption of the aortic arch and in coarctation of the aorta, with diagnostic, developmental, and surgical implications. (11024401)
2000
29
Critical left ventricular outflow tract obstruction due to accessory mitral valve tissue. (10978978)
2000
30
Potential mechanism of left ventricular outflow tract obstruction after mitral ring annuloplasty. (10047649)
1999
31
Echocardiographic predictors of left ventricular outflow tract obstruction and systolic anterior motion of the mitral valve after mitral valve reconstruction for myxomatous valve disease. (10588230)
1999
32
Dynamic left ventricular outflow tract obstruction as a potential mechanism of myocardial rupture after acute myocardial infarction. (10588241)
1999
33
Patch repair of subsemilunar conal septal defect resulting in severe left ventricular outflow tract obstruction. (9359571)
1997
34
Influence of right ventricular pacing site on left ventricular outflow tract obstruction in patients with hypertrophic obstructive cardiomyopathy. (8609346)
1996
35
Left ventricular outflow tract obstruction as a cause for hypotension and symptoms during dobutamine stress echocardiography. (8674261)
1996
36
Repair of complex left ventricular outflow tract obstruction with a pulmonary autograft. (7582142)
1995
37
Reduction of the left-ventricular outflow-tract obstruction by aortoventriculoplasty--long-term results of 96 patients. (8211925)
1993
38
Increased left ventricular outflow tract obstruction during exercise in patients with hypertrophic cardiomyopathy. (8426026)
1993
39
Left ventricular outflow tract obstruction with aortic arch anomalies and ventricular septal defect. (2241361)
1990
40
Accessory mitral valve leaflet causing aortic regurgitation and left ventricular outflow tract obstruction. Case report and review of published reports. (3285879)
1988
41
Noninvasive diagnosis of left ventricular outflow tract obstruction caused by a porcine mitral prosthesis. (3819212)
1987
42
Double outlet right ventricle with severe left ventricular outflow tract obstruction due to small ventricular septal defect and anomalous adherence of the mitral valve to the ventricular septum. (3437510)
1987
43
Left ventricular outflow tract obstruction with mitral valve replacement in small ventricular cavities. (3942435)
1986
44
Dynamic left ventricular outflow tract obstruction associated with pheochromocytoma. (7196146)
1981
45
The spectrum of left ventricular outflow tract obstruction: an overview. (7006467)
1980
46
Aortoventriculoplasty: a new technique for the treatment of left ventricular outflow tract obstruction. (131885)
1976
47
Parachute accessory anterior mitral valve leaflet causing left ventricular outflow tract obstruction. Report of a case with emphasis on the echocardiographic findings. (944108)
1976
48
Roentgenographic aspects of congenital left ventricular outflow tract obstruction. (5844924)
1965
49
50

Variations for Left Ventricular Outflow Tract Obstruction

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Expression for genes affiliated with Left Ventricular Outflow Tract Obstruction

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Search GEO for disease gene expression data for Left Ventricular Outflow Tract Obstruction.

Pathways for genes affiliated with Left Ventricular Outflow Tract Obstruction

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GO Terms for genes affiliated with Left Ventricular Outflow Tract Obstruction

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Biological processes related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1mitochondrial ATP synthesis coupled proton transportGO:004277610.3MT-ATP6, MT-ATP8
2ATP synthesis coupled proton transportGO:00159869.9MT-ATP6, MT-ATP8
3regulation of cell migrationGO:00303349.8ERBB4, NOTCH1
4cell fate commitmentGO:00451659.8ERBB4, NOTCH1
5regulation of cell motilityGO:20001459.8EGFR, ERBB4
6coronary vein morphogenesisGO:00031699.7NOTCH1, VEGFA
7cardiac vascular smooth muscle cell developmentGO:00609489.7NOTCH1, VEGFA
8positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:00614199.7NOTCH1, VEGFA
9peptidyl-tyrosine phosphorylationGO:00181089.7EGFR, ERBB4
10transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.7EGFR, ERBB4
11coronary artery morphogenesisGO:00609829.7NOTCH1, VEGFA
12epidermis developmentGO:00085449.6EGFR, NOTCH1
13positive regulation of epithelial cell proliferationGO:00506799.5EGFR, VEGFA
14branching morphogenesis of an epithelial tubeGO:00487549.5NOTCH1, VEGFA
15mammary gland alveolus developmentGO:00607499.4ERBB4, VEGFA
16positive regulation of neuroblast proliferationGO:00020529.3NOTCH1, VEGFA
17lung developmentGO:00303249.0NOTCH1, VEGFA
18positive regulation of cell migrationGO:00303358.9EGFR, NOTCH1, VEGFA
19vascular endothelial growth factor receptor signaling pathwayGO:00480108.4EGFR, ERBB4, VEGFA

Molecular functions related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor signaling protein tyrosine kinase activityGO:00047169.6EGFR, ERBB4
2ATPase activityGO:00168879.6MT-ATP6, MT-ATP8

Sources for Left Ventricular Outflow Tract Obstruction

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet