MCID: LFT009
MIFTS: 43

Left Ventricular Outflow Tract Obstruction malady

Category: Genetic diseases (common)

Aliases & Classifications for Left Ventricular Outflow Tract Obstruction

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Aliases & Descriptions for Left Ventricular Outflow Tract Obstruction:

Name: Left Ventricular Outflow Tract Obstruction 23 25
Hypoplastic Left Heart 23 25
Hypoplastic Left Heart Syndrome 66
Interupted Aortic Arch Type a 23
Coarctation of the Aorta 23
Aortic Valve Disease 2 66
 
Aortic Valve Stenosis 66
Aortic Valve Disorder 66
Bicuspid Aortic Valve 23
Aortic Valve Disease 23
Aortic Stenosis 23

Classifications:



Summaries for Left Ventricular Outflow Tract Obstruction

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MalaCards based summary: Left Ventricular Outflow Tract Obstruction, also known as hypoplastic left heart, is related to supravalvar aortic stenosis and aortic valve disease 2. An important gene associated with Left Ventricular Outflow Tract Obstruction is NOTCH1 (Notch 1), and among its related pathways are Dorso-ventral axis formation and Nuclear signaling by ERBB4. The drug alprostadil has been mentioned in the context of this disorder. Affiliated tissues include heart, lung and liver, and related mouse phenotypes are liver/biliary system and craniofacial.

Related Diseases for Left Ventricular Outflow Tract Obstruction

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Diseases related to Left Ventricular Outflow Tract Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1supravalvar aortic stenosis12.5
2aortic valve disease 212.5
3aortic valve disease 112.4
4familial bicuspid aortic valve12.4
5patent ductus arteriosus and bicuspid aortic valve with hand anomalies12.3
6aortic coarctation11.2
7cardiomyopathy11.0
8hypertrophic cardiomyopathy10.9
9transposition of the great arteries10.8
10ventricular septal defect10.8
11aortic valve insufficiency10.7
12cor triatriatum10.7
13myocardial infarction10.6
14accessory mitral valve tissue10.6
15cardiogenic shock10.5
16acute myocardial infarction10.5
17prp systemic amyloidosis10.4MT-ATP6, MT-ATP8
18le marec bracq picaud syndrome10.4MT-ATP6, MT-ATP8
19atrioventricular septal defect10.4
20syncope10.4
21right aortic arch10.4
22ischemia10.3
23aneurysm10.3
24congenital heart defects, nonsyndromic, 210.3
25mitochondrial complex v deficiency, mitochondrial 110.3
26mitochondrial complex v deficiency, mitochondrial 210.3
27pheochromocytoma10.2
28heart disease10.2
29amyloidosis10.2
30rheumatic disease10.2
31hallux varus and preaxial polysyndactyly10.2ERBB4, NOTCH1
32atrioventricular block10.1
33sarcoma10.1
34hypertensive heart disease10.1
35stress cardiomyopathy10.1
36mucopolysaccharidosis is10.0
37coronary artery disease10.0
38renal cell carcinoma10.0
39fabry disease10.0
40ebstein anomaly10.0
41pulmonary atresia with intact ventricular septum10.0
42hemolytic anemia10.0
43hypoplastic left heart syndrome10.0
44artery disease10.0
45infective endocarditis10.0
46endocarditis10.0
47hemiplegia10.0
48pericardial effusion10.0
49mitral valve stenosis10.0
50adenocarcinoma10.0

Comorbidity relations with Left Ventricular Outflow Tract Obstruction via Phenotypic Disease Network (PDN):

(show top 50)    (show all 70)
Hypertension, EssentialCoronary Artery Disease
Aplastic AnemiaOsteoporosis
Aortic Valve Disease 2Marfan Syndrome
Temporal ArteritisPeripheral Vascular Disease
Deficiency AnemiaPulmonary Hypertension
Acute Kidney FailureAcute Myocardial Infarction
Aortic AtherosclerosisChronic Kidney Failure
Hereditary AtaxiaIschemic Heart Disease
Familial Atrial FibrillationAtrioventricular Block
First-Degree Atrioventricular BlockThird-Degree Atrioventricular Block
Sinoatrial Node DiseaseTricuspid Valve Disease
AphasiaVenous Insufficiency
Left Bundle Branch HemiblockHeart Conduction Disease
Dressler's SyndromeMalignant Essential Hypertension
Benign Essential HypertensionAcquired Thrombocytopenia
Respiratory FailureDisseminated Intravascular Coagulation
Mobitz Type Ii Atrioventricular BlockSchizophreniform Disorder
Heart DiseaseHemopericardium
Iron Deficiency AnemiaEsophagitis
Hypertrophic CardiomyopathyPostinflammatory Pulmonary Fibrosis
Cerebral AtherosclerosisVertebral Artery Insufficiency
Acute CystitisGout
Right Bundle Branch BlockNutmeg Liver
Renal Artery AtheromaRheumatic Congestive Heart Failure
HypothyroidismMitral Valve Stenosis

Graphical network of the top 20 diseases related to Left Ventricular Outflow Tract Obstruction:



Diseases related to left ventricular outflow tract obstruction

Symptoms for Left Ventricular Outflow Tract Obstruction

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Drugs & Therapeutics for Left Ventricular Outflow Tract Obstruction

About this section

Drugs for Left Ventricular Outflow Tract Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Ethanol197164-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
2
Bupropion31334841-39-9, 34911-55-2444
Synonyms:
( -)-2-(tert-Butylamino)-3'-chloropropiophenone
( -)-2-(tert-Butylamino)-3'-chlorpropiophenon
(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
(+-)-Bupropion
.alpha.-(tert-Butylamino)-m-chloropropiophenone
1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one
2-(Tert-Butylamino)-3'-chloropropiophenone
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
34841-36-6 (hydrochloride)
34841-39-9
34911-55-2
AB00053756
AC-197
AC1L198Y
AMFEBUTAMONE HCl
Amfebutamon
Amfebutamona
Amfebutamona [INN-Spanish]
Amfebutamone
Amfebutamonum
Amfebutamonum [INN-Latin]
BPBio1_000042
BRD-A05186015-003-05-7
BRN 2101062
BSPBio_000038
BSPBio_002247
Bupropion (INN)
Bupropion (Old RN)
Bupropion (USAN)
Bupropion Hcl
Bupropion SR
Bupropion [INN:BAN]
Bupropion hydrocloride
C06860
CHEBI:3219
CHEMBL894
CID444
CPD000472526
D07591
DB01156
DivK1c_007050
Elont
 
HMS2051G10
HMS2089G14
Jsp006301
KBio1_001994
KBio2_002143
KBio2_004711
KBio2_007279
KBio3_001467
KBioGR_001168
KBioSS_002143
L000725
LS-122817
Lopac0_000166
MLS001424015
MolPort-003-845-432
NCGC00015122-06
NCGC00089751-02
NCI60_002714
NSC315851
Prestwick0_000249
Prestwick1_000249
Prestwick2_000249
Prestwick3_000249
SAM001246699
SMR000472526
SPBio_001817
SPBio_002257
SpecPlus_000954
Spectrum2_001659
Spectrum3_000644
Spectrum4_000614
Spectrum5_001406
Spectrum_001663
TL8002604
UNII-01ZG3TPX31
Wellbatrin
Wellbutrin
Wellbutrin SR
Wellbutrin XL
Zyban
alpha-(tert-butylamino)-m-chloropropiophenone
amfebutamonum
bupropion
3
Dopamine367851-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
4
CaffeineNutraceutical35858-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert-Pep
Alert-pep
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine
Caffeine (USP)
Caffeine (natural)
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffine
Cafipel
Caféine
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
DivK1c_000730
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Hycomine
Hycomine Compound
I14-4386
IDI1_000730
 
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Snapback Stimulant Powders
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stim
Synalgos-Dc
TNP00310
Teina
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
5KavaNutraceutical1379000-38-8

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract ObstructionRecruitingNCT02842242Phase 2
2Hypertrophic Cardiomyopathy Symptom Release by BX1514MRecruitingNCT02590809Phase 2
3Right Ventricular Outflow Tract StudyCompletedNCT01294839
4Bupropion & Cardio Birth Defect (Slone)CompletedNCT01597661
5Long-Term Results of DDD Pacing in Obstructive Hypertrophic CardiomyopathyCompletedNCT00001530
6Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDYRecruitingNCT01614717
7Multi Modal Cardiac Imaging Prior Transcatheter Aortic Valve ImplantationRecruitingNCT01805739
8Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency DepartmentRecruitingNCT02781207
9Pilot Trial: Comparison of Flow PatternsRecruitingNCT02288871
10Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung DiseaseRecruitingNCT00830726
11Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart SyndromeActive, not recruitingNCT01135485

Search NIH Clinical Center for Left Ventricular Outflow Tract Obstruction

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Genetic Tests for Left Ventricular Outflow Tract Obstruction

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Genetic tests related to Left Ventricular Outflow Tract Obstruction:

id Genetic test Affiliating Genes
1 Left Ventricular Outflow Tract Obstruction (lvoto)25 23 NOTCH1
2 Hypoplastic Left Heart25

Anatomical Context for Left Ventricular Outflow Tract Obstruction

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MalaCards organs/tissues related to Left Ventricular Outflow Tract Obstruction:

34
Heart, Lung, Liver, Testes

Animal Models for Left Ventricular Outflow Tract Obstruction or affiliated genes

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MGI Mouse Phenotypes related to Left Ventricular Outflow Tract Obstruction:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.4EGFR, NOTCH1, TAB2, VEGFA
2MP:00053828.2EGFR, ERBB4, NOTCH1, VEGFA
3MP:00107717.8EGFR, ERBB4, NOTCH1, TAB2, VEGFA
4MP:00053857.6EGFR, ERBB4, NOTCH1, TAB2, VEGFA
5MP:00053807.5EGFR, ERBB4, NOTCH1, TAB2, VEGFA

Publications for Left Ventricular Outflow Tract Obstruction

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Articles related to Left Ventricular Outflow Tract Obstruction:

(show top 50)    (show all 472)
idTitleAuthorsYear
1
Late Left Ventricular Outflow Tract Obstruction Following the Rastelli Operation: Expectations Out to 20 Years. (27587496)
2016
2
Left Ventricular Outflow Tract Obstruction: Coarctation of the Aorta, Interrupted Aortic Arch, and Borderline Left Ventricle. (27490616)
2016
3
Intentional Laceration of the Anterior Mitral Valve Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter MitralA Valve Replacement: Pre-Clinical Findings. (27609260)
2016
4
Surgical Ventricular Septal Myectomy for Patients With Noonan Syndrome and Symptomatic Left Ventricular Outflow Tract Obstruction. (26272816)
2015
5
Hybrid Stage I Palliation in a 1.1 kg, 28-Week Preterm Neonate With Posterior Malalignment Ventricular Septal Defect, Left Ventricular Outflow Tract Obstruction, and Coarctation of the Aorta. (25324263)
2014
6
Robot-assisted septal myectomy for hypertrophic cardiomyopathy with left ventricular outflow tract obstruction. (24793596)
2014
7
Left ventricular outflow tract obstruction following an uncomplicated primary percutaneous coronary intervention: a recognized but rare cause of cardiogenic shock. (24062935)
2013
8
A very unusual cause of mechanical left ventricular outflow tract obstruction. (23533200)
2013
9
Cardiogenic shock due to dynamic left ventricular outflow tract obstruction in acute myocardial infarction. (21452037)
2011
10
Left ventricular outflow tract obstruction after the modified single patch repair of atrioventricular septal defects: teasing fact from fiction. (20338382)
2010
11
Arterial switch and modified Konno procedure with detachment of the aortic root for transposition of the great arteries and left ventricular outflow tract obstruction. (20667390)
2010
12
Accessory mitral valve causing left ventricular outflow tract obstruction. (20719735)
2010
13
Syncope from dynamic left ventricular outflow tract obstruction simulating hypertrophic cardiomyopathy in a patient with primary AL-type amyloid heart disease. (19436787)
2009
14
Abnormal papillary muscle morphology is independently associated with increased left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. (17690158)
2008
15
Dynamic left ventricular outflow tract obstruction evoked by exercise echocardiography: prevalence and predictive factors in a prospective study. (18490319)
2008
16
Left ventricular rhabdomyoma with severe left ventricular outflow tract obstruction: development of delayed hemiplegia after cardiopulmonary bypass. (17803580)
2007
17
Takotsubo cardiomyopathy with left ventricular outflow tract obstruction. (16337511)
2006
18
Different effects of propranolol, phenylephrine, and saline volume loading on catecholamine-induced left ventricular outflow tract obstruction in acute coronary syndrome. (16607055)
2006
19
Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy. (16754630)
2006
20
Modified Nikaidoh procedure for transposition of great arteries, ventricular septal defect and left ventricular outflow tract obstruction. (17151976)
2006
21
Long-term results of apical aortic conduits in children with complex left ventricular outflow tract obstruction. (16305893)
2005
22
Multiple causes of left ventricular outflow tract obstruction in a 58-year-old woman. (15901301)
2005
23
Catecholamine therapy inducing dynamic left ventricular outflow tract obstruction. (15882688)
2005
24
Inferior myocardial infarction and shock associated with left ventricular outflow tract obstruction. (15322669)
2004
25
Hypovolemia-induced reversible severe mitral regurgitation due to left ventricular outflow tract obstruction. (12487637)
2002
26
Apico-aortic conduits in children with severe left ventricular outflow tract obstruction. (11834067)
2002
27
Left ventricular outflow tract obstruction after myocardial infarction due to a hyperdynamic basal septum. (11415498)
2001
28
Dynamic left ventricular outflow tract obstruction: an unusual mechanism mimicking anterior myocardial infarction with cardiogenic shock. (11214704)
2001
29
Comparison of left ventricular outflow tract obstruction in interruption of the aortic arch and in coarctation of the aorta, with diagnostic, developmental, and surgical implications. (11024401)
2000
30
Left ventricular outflow tract obstruction due to valve myxoma. (10881855)
2000
31
Potential mechanism of left ventricular outflow tract obstruction after mitral ring annuloplasty. (10047649)
1999
32
Dynamic left ventricular outflow tract obstruction in a patient with pheochromocytoma. (10737567)
1999
33
Patch repair of subsemilunar conal septal defect resulting in severe left ventricular outflow tract obstruction. (9359571)
1997
34
Influence of right ventricular pacing site on left ventricular outflow tract obstruction in patients with hypertrophic obstructive cardiomyopathy. (8609346)
1996
35
Left ventricular outflow tract obstruction as a cause for hypotension and symptoms during dobutamine stress echocardiography. (8674261)
1996
36
Relief of complex left ventricular outflow tract obstruction with pulmonary autografts. (7739236)
1995
37
Reversible steroid-induced hypertrophic cardiomyopathy with left ventricular outflow tract obstruction in two newborns. (7575834)
1995
38
Left ventricular outflow tract obstruction defined by active three-dimensional echocardiography using rotational transthoracic acquisition. (10150630)
1994
39
Reduction of the left-ventricular outflow-tract obstruction by aortoventriculoplasty--long-term results of 96 patients. (8211925)
1993
40
Increased left ventricular outflow tract obstruction during exercise in patients with hypertrophic cardiomyopathy. (8426026)
1993
41
Left ventricular outflow tract obstruction with aortic arch anomalies and ventricular septal defect. (2241361)
1990
42
Accessory mitral valve leaflet causing aortic regurgitation and left ventricular outflow tract obstruction. Case report and review of published reports. (3285879)
1988
43
Double outlet right ventricle with severe left ventricular outflow tract obstruction due to small ventricular septal defect and anomalous adherence of the mitral valve to the ventricular septum. (3437510)
1987
44
Left ventricular outflow tract obstruction with mitral valve replacement in small ventricular cavities. (3942435)
1986
45
Left ventricular outflow tract obstruction related to a valve prosthesis: case caused by a low-profile mitral prosthesis. (3974300)
1985
46
Dynamic left ventricular outflow tract obstruction associated with pheochromocytoma. (7196146)
1981
47
Cross-sectional echocardiographic localization of sites of left ventricular outflow tract obstruction. (942808)
1976
48
Left ventricular outflow-tract obstruction with an ostium primum defect. Report of two cases. (5437896)
1970
49
Roentgenographic aspects of congenital left ventricular outflow tract obstruction. (5844924)
1965
50
ANGIOCARDIOGRAPHIC FINDINGS IN IDIOPATHIC MYOCARDIAL HYPERTROPHY WITH RIGHT AND LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION. (14258277)
1965

Variations for Left Ventricular Outflow Tract Obstruction

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Expression for genes affiliated with Left Ventricular Outflow Tract Obstruction

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Search GEO for disease gene expression data for Left Ventricular Outflow Tract Obstruction.

Pathways for genes affiliated with Left Ventricular Outflow Tract Obstruction

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GO Terms for genes affiliated with Left Ventricular Outflow Tract Obstruction

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Cellular components related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial proton-transporting ATP synthase complexGO:00057539.7MT-ATP6, MT-ATP8
2receptor complexGO:00432359.0EGFR, ERBB4, NOTCH1

Biological processes related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1mitochondrial ATP synthesis coupled proton transportGO:004277610.2MT-ATP6, MT-ATP8
2ATP biosynthetic processGO:000675410.2MT-ATP6, MT-ATP8
3cell fate commitmentGO:004516510.1ERBB4, NOTCH1
4response to hyperoxiaGO:005509310.0MT-ATP6, MT-ATP8
5positive regulation of cardiac muscle cell proliferationGO:006004510.0ERBB4, NOTCH1
6coronary artery morphogenesisGO:00609829.9NOTCH1, VEGFA
7cardiac vascular smooth muscle cell developmentGO:00609489.9NOTCH1, VEGFA
8positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:00614199.9NOTCH1, VEGFA
9coronary vein morphogenesisGO:00031699.9NOTCH1, VEGFA
10branching morphogenesis of an epithelial tubeGO:00487549.8NOTCH1, VEGFA
11ERBB2 signaling pathwayGO:00381289.8EGFR, ERBB4
12tube formationGO:00351489.7NOTCH1, VEGFA
13regulation of cell motilityGO:20001459.6EGFR, ERBB4
14cellular response to vascular endothelial growth factor stimulusGO:00359249.6NOTCH1, VEGFA
15positive regulation of MAP kinase activityGO:00434069.5EGFR, VEGFA
16mammary gland alveolus developmentGO:00607499.4ERBB4, VEGFA
17lactationGO:00075959.3ERBB4, VEGFA
18lung developmentGO:00303249.1EGFR, NOTCH1, VEGFA
19positive regulation of neuroblast proliferationGO:00020529.0NOTCH1, VEGFA
20positive regulation of protein phosphorylationGO:00019348.9EGFR, ERBB4, VEGFA
21positive regulation of epithelial cell proliferationGO:00506798.9EGFR, NOTCH1, VEGFA
22heart developmentGO:00075078.9ERBB4, NOTCH1, TAB2
23positive regulation of cell migrationGO:00303358.8EGFR, NOTCH1, VEGFA
24positive regulation of cell proliferationGO:00082848.1EGFR, ERBB4, NOTCH1, VEGFA

Molecular functions related to Left Ventricular Outflow Tract Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hydrogen ion transmembrane transporter activityGO:00150789.8MT-ATP6, MT-ATP8
2transmembrane transporter activityGO:00228579.8MT-ATP6, MT-ATP8
3receptor signaling protein tyrosine kinase activityGO:00047169.7EGFR, ERBB4
4transmembrane receptor protein tyrosine kinase activityGO:00047149.3EGFR, ERBB4
5phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:00469349.2EGFR, ERBB4

Sources for Left Ventricular Outflow Tract Obstruction

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet