MCID: LMY001
MIFTS: 22

Leiomyoma Cutis

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Leiomyoma Cutis

MalaCards integrated aliases for Leiomyoma Cutis:

Name: Leiomyoma Cutis 12 14
Cutaneous Leiomyoma 12 29 69
Leiomyoma of the Skin 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5132
NCIt 47 C4482
SNOMED-CT 64 254767008
UMLS 69 C0346064

Summaries for Leiomyoma Cutis

MalaCards based summary : Leiomyoma Cutis, also known as cutaneous leiomyoma, is related to leiomyomatosis and renal cell cancer and leiomyoma. An important gene associated with Leiomyoma Cutis is FH (Fumarate Hydratase). The drugs Acetylcholine and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include skin.

Related Diseases for Leiomyoma Cutis

Diseases related to Leiomyoma Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 leiomyomatosis and renal cell cancer 11.9
2 leiomyoma 10.4
3 leiomyosarcoma 9.7
4 leydig cell tumor 9.5 CLEC2A FH
5 pericardium leiomyoma 9.2 CLEC2A FH

Graphical network of the top 20 diseases related to Leiomyoma Cutis:



Diseases related to Leiomyoma Cutis

Symptoms & Phenotypes for Leiomyoma Cutis

Drugs & Therapeutics for Leiomyoma Cutis

Drugs for Leiomyoma Cutis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 2 51-84-3 187
2
Bevacizumab Approved, Investigational Phase 2 216974-75-3
3 abobotulinumtoxinA Phase 2
4 Botulinum Toxins Phase 2
5 Botulinum Toxins, Type A Phase 2
6 Cholinergic Agents Phase 2
7 Neuromuscular Agents Phase 2
8 Neurotransmitter Agents Phase 2
9 onabotulinumtoxinA Phase 2
10 Peripheral Nervous System Agents Phase 2
11 Angiogenesis Inhibitors Phase 2
12 Angiogenesis Modulating Agents Phase 2
13
Erlotinib Hydrochloride Phase 2 183319-69-9 176871
14 Protein Kinase Inhibitors Phase 2
15 Anesthetics

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Randomized Pilot Study for the Treatment of Cutaneous Leiomyomas With Botulinum Toxin Completed NCT00971620 Phase 2
2 A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer Recruiting NCT01130519 Phase 2 Bevacizumab;Erlotinib
3 Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer Recruiting NCT00050752
4 Directed Ablation of Uterine Fibroids Using a Noninvasive Approach Not yet recruiting NCT03219385
5 Radiofrequency Ablation of Uterine Fibroids Terminated NCT00584207 Early Phase 1
6 Uterine Artery Embolization(UAE) Versus High-Intensity-Focused-Ultrasound(HIFU) for Treatment of Uterine Fibroids Terminated NCT01834703

Search NIH Clinical Center for Leiomyoma Cutis

Genetic Tests for Leiomyoma Cutis

Genetic tests related to Leiomyoma Cutis:

id Genetic test Affiliating Genes
1 Cutaneous Leiomyoma 29

Anatomical Context for Leiomyoma Cutis

MalaCards organs/tissues related to Leiomyoma Cutis:

39
Skin

Publications for Leiomyoma Cutis

Articles related to Leiomyoma Cutis:

(show all 22)
id Title Authors Year
1
Leiomyoma cutis: a focused review on presentation, management, and association with malignancy. ( 25605645 )
2015
2
Bilateral Multisegmental Zosteriform Leiomyoma Cutis: A Rare Entity. ( 26120160 )
2015
3
Leiomyoma cutis: a clinicopathological series of 37 cases. ( 21430885 )
2010
4
Multiple leiomyoma cutis associated with Becker's nevus. ( 8973041 )
1996
5
Leiomyoma cutis and leiomyosarcoma: a 10-year study and a short review. ( 6833615 )
1983
6
Leiomyoma cutis. ( 6678281 )
1983
7
Tumor conference #40: leiomyoma cutis of the cheek. ( 7061755 )
1982
8
Leiomyoma cutis: an electron microscope study. ( 5431552 )
1970
9
Leiomyoma cutis and its surgical treatment. ( 13974004 )
1962
10
Leiomyoma cutis. ( 13607906 )
1958
11
Leiomyoma cutis. ( 14789226 )
1951
12
Leiomyoma cutis. ( 15419829 )
1950
13
Leiomyoma cutis (zosteriform). ( 18135865 )
1949
14
Leiomyoma cutis. ( 20251574 )
1947
15
Leiomyoma cutis. ( 20342296 )
1947
16
Leiomyoma Cutis. ( 19993516 )
1947
17
Leiomyoma cutis. ( 20277331 )
1946
18
A case of leiomyoma cutis. ( 20287036 )
1946
19
Leiomyoma Cutis. ( 19990680 )
1936
20
Leiomyoma Cutis. ( 19988170 )
1931
21
Leiomyoma Cutis Multiplex. ( 19987146 )
1929
22
Leiomyoma Cutis. ( 19985653 )
1927

Variations for Leiomyoma Cutis

Expression for Leiomyoma Cutis

Search GEO for disease gene expression data for Leiomyoma Cutis.

Pathways for Leiomyoma Cutis

GO Terms for Leiomyoma Cutis

Sources for Leiomyoma Cutis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....