MCID: LMY001
MIFTS: 21

Leiomyoma Cutis

Categories: Skin diseases, Cancer diseases

Aliases & Classifications for Leiomyoma Cutis

MalaCards integrated aliases for Leiomyoma Cutis:

Name: Leiomyoma Cutis 12 14
Cutaneous Leiomyoma 12 28 69
Leiomyoma of the Skin 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5132
NCIt 46 C4482
SNOMED-CT 64 254767008
UMLS 69 C0346064

Summaries for Leiomyoma Cutis

MalaCards based summary : Leiomyoma Cutis, also known as cutaneous leiomyoma, is related to hereditary leiomyomatosis and renal cell cancer and leiomyoma. An important gene associated with Leiomyoma Cutis is FH (Fumarate Hydratase). The drugs Acetylcholine and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include skin.

Related Diseases for Leiomyoma Cutis

Diseases related to Leiomyoma Cutis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hereditary leiomyomatosis and renal cell cancer 12.0
2 leiomyoma 10.4
3 leiomyosarcoma 9.8
4 skin sarcoma 9.4 CLEC2A FH

Symptoms & Phenotypes for Leiomyoma Cutis

Drugs & Therapeutics for Leiomyoma Cutis

Drugs for Leiomyoma Cutis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 2 51-84-3 187
2
Bevacizumab Approved, Investigational Phase 2 216974-75-3
3 abobotulinumtoxinA Phase 2
4 Botulinum Toxins Phase 2
5 Botulinum Toxins, Type A Phase 2
6 Cholinergic Agents Phase 2
7 Neuromuscular Agents Phase 2
8 Neurotransmitter Agents Phase 2
9 onabotulinumtoxinA Phase 2
10 Peripheral Nervous System Agents Phase 2
11 Angiogenesis Inhibitors Phase 2
12 Angiogenesis Modulating Agents Phase 2
13
Erlotinib Hydrochloride Phase 2 183319-69-9 176871
14 Protein Kinase Inhibitors Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Pilot Study for the Treatment of Cutaneous Leiomyomas With Botulinum Toxin Completed NCT00971620 Phase 2
2 A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer Recruiting NCT01130519 Phase 2 Bevacizumab;Erlotinib
3 Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer Recruiting NCT00050752

Search NIH Clinical Center for Leiomyoma Cutis

Genetic Tests for Leiomyoma Cutis

Genetic tests related to Leiomyoma Cutis:

# Genetic test Affiliating Genes
1 Cutaneous Leiomyoma 28

Anatomical Context for Leiomyoma Cutis

MalaCards organs/tissues related to Leiomyoma Cutis:

38
Skin

Publications for Leiomyoma Cutis

Articles related to Leiomyoma Cutis:

(show all 23)
# Title Authors Year
1
Leiomyoma cutis: a focused review on presentation, management, and association with malignancy. ( 25605645 )
2015
2
Bilateral Multisegmental Zosteriform Leiomyoma Cutis: A Rare Entity. ( 26120160 )
2015
3
Leiomyoma cutis: a clinicopathological series of 37 cases. ( 21430885 )
2010
4
Multiple leiomyoma cutis associated with Becker's nevus. ( 8973041 )
1996
5
Leiomyoma cutis and leiomyosarcoma: a 10-year study and a short review. ( 6833615 )
1983
6
Leiomyoma cutis. ( 6678281 )
1983
7
Tumor conference #40: leiomyoma cutis of the cheek. ( 7061755 )
1982
8
Leiomyoma Cutis (A clinico-pathological review with a case report). ( 29139414 )
1973
9
Leiomyoma cutis: an electron microscope study. ( 5431552 )
1970
10
Leiomyoma cutis and its surgical treatment. ( 13974004 )
1962
11
Leiomyoma cutis. ( 13607906 )
1958
12
Leiomyoma cutis. ( 14789226 )
1951
13
Leiomyoma cutis. ( 15419829 )
1950
14
Leiomyoma cutis (zosteriform). ( 18135865 )
1949
15
Leiomyoma Cutis. ( 19993516 )
1947
16
Leiomyoma cutis. ( 20251574 )
1947
17
Leiomyoma cutis. ( 20342296 )
1947
18
Leiomyoma cutis. ( 20277331 )
1946
19
A case of leiomyoma cutis. ( 20287036 )
1946
20
Leiomyoma Cutis. ( 19990680 )
1936
21
Leiomyoma Cutis. ( 19988170 )
1931
22
Leiomyoma Cutis Multiplex. ( 19987146 )
1929
23
Leiomyoma Cutis. ( 19985653 )
1927

Variations for Leiomyoma Cutis

Expression for Leiomyoma Cutis

Search GEO for disease gene expression data for Leiomyoma Cutis.

Pathways for Leiomyoma Cutis

GO Terms for Leiomyoma Cutis

Sources for Leiomyoma Cutis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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