MCID: LMY003
MIFTS: 41

Leiomyomatosis malady

Category: Cancer diseases

Aliases & Classifications for Leiomyomatosis

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Aliases & Descriptions for Leiomyomatosis:

Name: Leiomyomatosis 11 50 39 13 68
 
Leiomyomatosis, No Icd-O Subtype 11

Classifications:



External Ids:

Disease Ontology11 DOID:5138
MeSH39 D018231
SNOMED-CT62 189789002, 75210008
NCIt45 C3748

Summaries for Leiomyomatosis

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MalaCards based summary: Leiomyomatosis, also known as leiomyomatosis, no icd-o subtype, is related to leiomyomatosis and renal cell cancer and leiomyosarcoma. An important gene associated with Leiomyomatosis is FH (Fumarate Hydratase), and among its related pathways are Pyruvate metabolism and NCAM1 interactions. Affiliated tissues include uterus, heart and kidney, and related mouse phenotypes are normal and cardiovascular system.

Related Diseases for Leiomyomatosis

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Diseases related to Leiomyomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 142)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyomatosis and renal cell cancer34.4FH, LDHA
2leiomyosarcoma30.5ESR1, PGR
3vulvar leiomyoma26.0COL4A3, COL4A4, COL4A5, COL4A6, ESR1, FH
4intravenous leiomyomatosis12.2
5disseminated peritoneal leiomyomatosis12.0
6diffuse peritoneal leiomyomatosis11.9
7leiomyomatosis, esophageal and vulval, with nephropathy11.9
8uterus intravascular leiomyomatosis11.7
9uterine corpus leiomyomatosis11.7
10uterine corpus diffuse leiomyomatosis11.7
11leiomyomatosis of esophagus, cataract and hematuria11.7
12x-linked diffuse leiomyomatosis-alport syndrome11.7
13alport syndrome11.2
14leiomyoma of vulva and esophagus10.9
15multiple cutaneous and uterine leiomyomas10.9
16renal cell carcinoma, papillary10.8
17early-onset generalized limb-onset dystonia10.6COL4A5, COL4A6
18vulvar angiokeratoma10.5ESR1, PGR
19central nervous system organ benign neoplasm10.5ESR1, PGR
20fallopian tube benign neoplasm10.5ESR1, PGR
21appendix leiomyoma10.5ESR1, PGR
22mixed cell adenoma10.5ESR1, PGR
23gelatinous ascites10.5ESR1, PGR
24deafness, autosomal dominant 8/1210.5ESR1, PGR
25perinatal intestinal perforation10.5ESR1, PGR
26trigeminal nerve disease10.5ESR1, PGR
27glottis verrucous carcinoma10.5ESR1, PGR
28bartholin's gland adenoid cystic carcinoma10.5ESR1, PGR
29bladder colonic type adenocarcinoma10.5ESR1, PGR
30her2-receptor positive breast cancer10.5ESR1, PGR
31adenocarcinoma in situ10.5ESR1, PGR
32gallbladder squamous cell carcinoma10.5ESR1, PGR
33amyloid tumor10.5ESR1, PGR
34extracranial neuroblastoma10.5ESR1, PGR
35malignant mediastinal neurogenic neoplasm10.5ESR1, PGR
36retroperitoneum carcinoma10.5ESR1, PGR
37uterine body mixed cancer10.5ESR1, PGR
38infiltrative basal cell carcinoma10.4ESR1, PGR
39fallopian tube germ cell cancer10.4ESR1, PGR
40bile duct mucoepidermoid carcinoma10.4ESR1, PGR
41cholesteatoma of external ear10.4ESR1, PGR
42allergic cutaneous vasculitis10.4ESR1, PGR
43bladder clear cell adenocarcinoma10.4ESR1, PGR
44anomalous left coronary artery from the pulmonary artery10.4ESR1, PGR
45adenosine monophosphate deaminase 1 deficiency10.4ESR1, PGR
46torticollis, familial10.4FH, SDHB
47vibratory urticaria10.4ESR1, PGR
48pleomorphic carcinoma10.4ESR1, PGR
49immune system cancer10.4ESR1, PGR
50ampulla of vater neoplasm10.4ESR1, PGR

Graphical network of the top 20 diseases related to Leiomyomatosis:



Diseases related to leiomyomatosis

Symptoms & Phenotypes for Leiomyomatosis

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MGI Mouse Phenotypes related to Leiomyomatosis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.3COL4A6, ESR1, GNRH1, LDHA, MED12, PGR
2MP:00053858.2COL4A3, COL4A5, ESR1, LDHA, MED12, PGR
3MP:00053877.9COL4A3, COL4A4, COL4A5, ESR1, GNRH1, LDHA
4MP:00053677.7COL4A3, COL4A4, COL4A5, ESR1, FH, GNRH1
5MP:00053767.6COL4A3, COL4A4, COL4A5, ESR1, FH, GNRH1
6MP:00107687.4COL4A3, COL4A4, COL4A5, ESR1, FH, LDHA

Drugs & Therapeutics for Leiomyomatosis

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Drugs for Leiomyomatosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EthanolapprovedPhase 4204364-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
2
AcetylcholineapprovedPhase 277651-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
3
Bevacizumabapproved, investigationalPhase 21968216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
4
MetforminapprovedPhase 1, Phase 21746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
5Neurotransmitter AgentsPhase 217734
6Peripheral Nervous System AgentsPhase 222776
7Neuromuscular AgentsPhase 21129
8onabotulinumtoxinAPhase 2626
9abobotulinumtoxinAPhase 2626
10incobotulinumtoxinAPhase 2635
11Botulinum ToxinsPhase 2669
12Botulinum Toxins, Type APhase 2630
13Cholinergic AgentsPhase 23846
14Hypoglycemic AgentsPhase 1, Phase 25733
15Protein Kinase InhibitorsPhase 23612
16
Erlotinib HydrochloridePhase 2798183319-69-9176871
Synonyms:
 
erlotinib hydrochloride
17Angiogenesis InhibitorsPhase 24143
18Angiogenesis Modulating AgentsPhase 24072
19
Progesteroneapproved, vet_approved53757-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE)CompletedNCT00628901Phase 4
2Randomized Pilot Study for the Treatment of Cutaneous Leiomyomas With Botulinum ToxinCompletedNCT00971620Phase 2
3A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell CancerRecruitingNCT01130519Phase 2
4Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell CarcinomaRecruitingNCT02495103Phase 1, Phase 2
5Comparison Study in the Treatment of Uterine Fibroids Uterine Fibroid Embolization Using BeadBlock™ Embolic AgentCompletedNCT00361036Phase 1
6Surgery for Intravenous LeiomyomatosisCompletedNCT01707862
7Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)CompletedNCT00001869
8Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal CancerRecruitingNCT00050752
9French National Registry of Rare Peritoneal Surface MalignanciesActive, not recruitingNCT02834169
10Establishment of Fibroid Tissue BankTerminatedNCT00710346

Search NIH Clinical Center for Leiomyomatosis


Cochrane evidence based reviews: leiomyomatosis

Genetic Tests for Leiomyomatosis

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Anatomical Context for Leiomyomatosis

About this section

MalaCards organs/tissues related to Leiomyomatosis:

36
Uterus, Heart, Kidney, Smooth muscle, Lymph node, Colon, Lung

Publications for Leiomyomatosis

About this section

Articles related to Leiomyomatosis:

(show top 50)    (show all 640)
idTitleAuthorsYear
1
A Case of Simultaneous Benign Metastasizing Leiomyomas and Disseminated Peritoneal Leiomyomatosis Following Endoscopic Power Morcellation for Uterine Disease. (27748666)
2017
2
Different surgical strategies of patients with intravenous leiomyomatosis. (27631266)
2016
3
Pelvic Intravenous Leiomyomatosis - Case Report. (27529764)
2016
4
Successful One-Stage Operative Resection of an Intravenous Leiomyomatosis Involving the Right-Sided Heart Chambers and Pulmonary Artery. (27146232)
2016
5
Unusual intravascular leiomyomatosis arising from the pulmonary artery. (27076367)
2016
6
Factors Associated With Recurrence After Surgical Resection in Women With Intravenous Leiomyomatosis. (27741175)
2016
7
Leiomyomatosis Peritonealis Disseminata (LPD) ten years after laparoscopic myomectomy associated with ascites and lymph nodes enlargement: a case report. (27280492)
2016
8
A twist on piloleiomyoma: segmental cutaneous leiomyomatosis. (27584971)
2016
9
IV Leiomyomatosis on FDG PET/CT. (26914578)
2016
10
Intravenous leiomyomatosis with right atrium extension in two patients: A case report. (27900095)
2016
11
Loss of Fumarate Hydratase and Aberrant Protein Succination Detected With S-(2-Succino)-Cysteine Staining to Identify Patients With Multiple Cutaneous and Uterine Leiomyomatosis and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome. (27097334)
2016
12
Surgical Treatment Strategies of Intravenous Leiomyomatosis withRight Cardiac Cavities Extension. (27594158)
2016
13
Leiomyomatosis peritonealis disseminata: A case report and review of the literature. (27284430)
2016
14
Complete Penetrance and Absence of Intrafamilial Variability in a Large Family with Hereditary Leiomyomatosis and Renal Cell Carcinoma. (27161211)
2016
15
The value of (18)F-FDG PET/CT in the diagnosis of uterine intravenous leiomyomatosis extended into the right atrium. (27331217)
2016
16
Radical nephrectomy and regional lymph node dissection for locally advanced type 2 papillary renal cell carcinoma in an at-risk individual from a family with hereditary leiomyomatosis and renal cell cancer: a case report. (26983443)
2016
17
Intracardiac leiomyomatosis presenting as an intraoperative consultation. (27067811)
2016
18
Successful One Stage Surgical Removal of Intravenous Leiomyomatosis with On Pump Beating Heart Technique. (26847505)
2016
19
Intravascular adenomyomatosis: a rare variant of A+ntravascular leiomyomatosis. (27924660)
2016
20
First Presentation of Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome in Pregnancy. (26902252)
2016
21
Disseminated peritoneal leiomyomatosis postmorcellated resection of uterine leiomyomatous tissue. (27649643)
2016
22
Intravenous leiomyomatosis treated with radical hysterectomy and adjuvant aromatase inhibitor therapy. (27436168)
2016
23
A Unique Case of Diffuse Intestinal and Colonic Leiomyomatosis. (27215367)
2016
24
Intracardiac Leiomyomatosis - an Unusual Cause of Syncope in a Middle-Aged Woman. (27743856)
2016
25
A Rare Concurrence of Leiomyomatosis Peritonealis Disseminata, Leiomyosarcoma of the Pelvis and Leiomyomatous Nodule of the Liver. (26998373)
2016
26
Intravenous leiomyomatosis: an unusual intermediate between benign and malignant uterine smooth muscle tumors. (26892441)
2016
27
Immunohistochemistry for 2-Succinocysteine (2SC) and Fumarate Hydratase (FH) in Cutaneous Leiomyomas May Aid in Identification of Patients With HLRCC (Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome). (26945337)
2016
28
A Case of Hereditary Leiomyomatosis and Renal Cell Carcinoma. (27144040)
2016
29
Intravenous leiomyomatosis with intracardiac extension depicted on computed tomography and magnetic resonance imaging scans: A report of two cases and a review of the literature. (27313775)
2016
30
Intravenous Leiomyomatosis in the Parametrium. (26802907)
2016
31
Complete resection of intracardiac leiomyomatosis through an abdominal approach under peripheral cardiopulmonary bypass. (27436095)
2016
32
Surgical Treatment of Intracardiac-Extending Intravenous Leiomyomatosis: A Single Center Experience. (27355139)
2016
33
Iatrogenic parasitic leiomyoma and leiomyomatosis peritonealis disseminata following uterine morcellation. (27125448)
2016
34
Intravenous leiomyomatosis with inferior vena cava or intracardiac extension and concurrent bilateral multiple pulmonary nodules: A report of 2 cases. (27583911)
2016
35
Fumarate Hydratase-deficient Renal Cell Carcinoma Is Strongly Correlated With Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome. (26900816)
2016
36
Uterine leiomyomatosis with intracardiac extension. (27999133)
2016
37
Leiomyomatosis peritonealis disseminata: case report and review of the literature. (27426654)
2016
38
Vanishing intravenous leiomyomatosis after hysterectomy: Assessment of the need to perform complete resection. (27080990)
2016
39
Uterine Intravenous Leiomyomatosis with Intracardiac Extension and Pulmonary Benign Metastases on FDG PET/CT: A Case Report. (26957916)
2016
40
Management of Intravenous Leiomyomatosis of Uterus with Extension to Heart. (26838087)
2016
41
Paradoxical Tumor Embolism and Recurrent Intracardiac Mass From Uterine Intravenous Leiomyomatosis. (27554224)
2016
42
Hereditary leiomyomatosis and renal cell cancer syndrome: identification and clinical characterization of a novel mutation in the FH gene in a Colombian family. (27566483)
2016
43
Intravenous leiomyomatosis: an unusual growth pattern in uterine myomas. (26850648)
2016
44
Circumferential anorectal leiomyomatosis. (27023346)
2016
45
Intravascular leiomyomatosis: an exceptional entity. (27328511)
2016
46
One-stage complete resection of giant intracardiac leiomyomatosis with moderate hypothermia extracorporeal circulation and beating heart technique with 36A months follow-up-a case report. (27072649)
2016
47
Leiomyomatosis peritonealis disseminata in postmenopausal women: a case report with review of literature. (27785109)
2016
48
Intravenous leiomyomatosis disguised as a large deep vein thrombosis. (27761178)
2016
49
Molecular Genetic Alterations in Renal Cell Carcinomas With Tubulocystic Pattern: Tubulocystic Renal Cell Carcinoma, Tubulocystic Renal Cell Carcinoma With Heterogenous Component and Familial Leiomyomatosis-associated Renal Cell Carcinoma. Clinicopathologic and Molecular Genetic Analysis of 15 Cases. (26447894)
2015
50
Hereditary leiomyomatosis associated with renal cell carcinoma. (25477250)
2015

Variations for Leiomyomatosis

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Expression for genes affiliated with Leiomyomatosis

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Search GEO for disease gene expression data for Leiomyomatosis.

Pathways for genes affiliated with Leiomyomatosis

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Pathways related to Leiomyomatosis according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6FH, LDHA
29.2COL4A3, COL4A4, COL4A5
3
Show member pathways
9.0FH, LDHA, SDHB
4
Show member pathways
8.9COL4A3, COL4A4, COL4A5, COL4A6
58.9COL4A3, COL4A4, COL4A5, COL4A6
6
Show member pathways
8.9COL4A3, COL4A4, COL4A5, COL4A6
7
Show member pathways
8.9COL4A3, COL4A4, COL4A5, COL4A6
88.9COL4A3, COL4A4, COL4A5, COL4A6
9
Show member pathways
8.9COL4A3, COL4A4, COL4A5, COL4A6
108.9COL4A3, COL4A4, COL4A5, COL4A6
118.9COL4A3, COL4A4, COL4A5, COL4A6
128.9COL4A3, COL4A4, COL4A5, COL4A6
138.9COL4A3, COL4A4, COL4A5, COL4A6
148.9COL4A3, COL4A4, COL4A5, COL4A6
158.9COL4A3, COL4A4, COL4A5, COL4A6
16
Show member pathways
8.9COL4A3, COL4A4, COL4A5, COL4A6
178.6COL4A3, COL4A4, COL4A5, COL4A6, FH
18
Show member pathways
8.1COL4A3, COL4A4, COL4A5, COL4A6, GNRH1

GO Terms for genes affiliated with Leiomyomatosis

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Cellular components related to Leiomyomatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1basal laminaGO:000560510.4COL4A4, COL4A5
2basement membraneGO:00056049.5COL4A3, COL4A4, COL4A5, COL4A6
3collagen type IV trimerGO:00055879.5COL4A3, COL4A4, COL4A5, COL4A6
4endoplasmic reticulum lumenGO:00057888.9COL4A3, COL4A4, COL4A5, COL4A6

Biological processes related to Leiomyomatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intracellular steroid hormone receptor signaling pathwayGO:003051810.2ESR1, MED12
2glomerular basement membrane developmentGO:003283610.1COL4A3, COL4A4
3transcription initiation from RNA polymerase II promoterGO:00063679.7ESR1, MED12, PGR
4tricarboxylic acid cycleGO:00060999.7FH, SDHB
5collagen catabolic processGO:00305749.6COL4A3, COL4A4, COL4A5, COL4A6
6extracellular matrix organizationGO:00301989.5COL4A3, COL4A4, COL4A5, COL4A6

Molecular functions related to Leiomyomatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1steroid bindingGO:00054969.8ESR1, PGR
2extracellular matrix structural constituentGO:00052019.3COL4A3, COL4A4, COL4A5, COL4A6

Sources for Leiomyomatosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet