Aliases & Classifications for Leiomyomatosis

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Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 42NCIt, 59SNOMED-CT
See all sources

Aliases & Descriptions for Leiomyomatosis:

Name: Leiomyomatosis 10 47 12 65 36
 
Leiomyomatosis, No Icd-O Subtype 10


Classifications:



External Ids:

Disease Ontology10 DOID:5138
MeSH36 D018231
SNOMED-CT59 75210008
NCIt42 C3748

Summaries for Leiomyomatosis

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Wikipedia:68 A leiomyoma (plural leiomyomas or leiomyomata) (leio- + myo- + -oma, \"smooth-muscle tumor\") is a... more...

MalaCards based summary: Leiomyomatosis, also known as leiomyomatosis, no icd-o subtype, is related to leiomyomatosis and renal cell cancer and tuberous sclerosis. An important gene associated with Leiomyomatosis is FH (Fumarate Hydratase), and among its related pathways are NCAM1 interactions and PI3K-Akt signaling pathway. Affiliated tissues include uterus, smooth muscle and heart, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Related Diseases for Leiomyomatosis

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Diseases related to Leiomyomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 225)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyomatosis and renal cell cancer31.6FH, SDHB
2tuberous sclerosis30.4ESR1, PGR
3reproductive system disease29.6ESR1, FH, MED12, PGR
4leiomyosarcoma28.3COL4A3, COL4A4, COL4A5, COL4A6, ESR1, FH
5intravenous leiomyomatosis11.0
6esophagitis10.7
7peritonitis10.7
8alport syndrome10.7
9leiomyoma10.7
10disseminated peritoneal leiomyomatosis10.6
11renal cell carcinoma10.6
12endometriosis10.5
13diffuse peritoneal leiomyomatosis10.3
14uterus intravascular leiomyomatosis10.3
15benign metastasizing leiomyoma10.3
16leiomyomatosis, esophageal and vulval, with nephropathy10.3
17autosomal dominant charcot-marie-tooth disease type 2n10.3COL4A5, COL4A6
18myoma10.3
19uterine fibroid10.3
20familial streblodactyly10.2FH, SDHB
21uterine corpus diffuse leiomyomatosis10.2
22kidney cancer10.2
23pulmonary embolism10.2
24uterine corpus leiomyomatosis10.2
25hypoglossal nerve neoplasm10.2ESR1, GNRH1
26vulvar melanoma10.2ESR1, PGR
27childhood teratocarcinoma of the testis10.2ESR1, PGR
28rectum rhabdomyosarcoma10.2ESR1, PGR
29vestibulocochlear nerve disease10.2ESR1, PGR
30vulvar disease10.2ESR1, PGR
31aromatase excess syndrome10.2ESR1, GNRH1
32vulvar sarcoma10.2ESR1, PGR
33glaucoma iridogoniodysgenesia10.2ESR1, PGR
34progesterone resistance10.2ESR1, PGR
35metachronous kidney wilms' tumor10.2ESR1, PGR
36sarcomatoid basal cell carcinoma10.2ESR1, PGR
37perineural angioma10.2ESR1, PGR
38malignant cystic nephroma10.2ESR1, PGR
39bartonellosis10.2ESR1, PGR
40anus lymphoma10.2ESR1, PGR
41papillary extrahepatic bile duct adenocarcinoma10.2ESR1, PGR
42vagina leiomyosarcoma10.2ESR1, PGR
43esophageal adenoid cystic carcinoma10.2ESR1, PGR
44primary hypertrophic osteoarthropathy10.2ESR1, PGR
45follicular basal cell carcinoma10.2ESR1, PGR
46chest wall lymphoma10.2ESR1, PGR
47oxyphilic endometrial endometrioid adenocarcinoma10.2ESR1, PGR
48cervical mucinous adenocarcinoma10.2ESR1, PGR
49germ cell and embryonal cancer10.2ESR1, PGR
50subclavian steal syndrome10.2ESR1, PGR

Graphical network of the top 20 diseases related to Leiomyomatosis:



Diseases related to leiomyomatosis

Symptoms for Leiomyomatosis

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Drugs & Therapeutics for Leiomyomatosis

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Drugs for Leiomyomatosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Phase 4
2
Erlotinibapproved, investigationalPhase 2759183321-74-6176870, 176871
Synonyms:
183321-74-6
4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline
774
AB1004620
AC-399
AC1L42EI
AKOS000282911
AQ4
BCB03_000783
C400278
CHEBI:114785
CHEMBL553
CID176870
CP 358,774
CP-258
CP-358,774
CP-358774
DB00530
EN002711
Erlotinib
Erlotinib Base
Erlotinib Hydrochloride
Erlotinib(Tarceva)
Erlotinib, OS-774
 
Erlotinin
FT-0083688
HMS2089F05
I01-1241
K00241
Kinome_3317
LS-184395
MolPort-003-847-084
N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
NCGC00164574-01
NSC 718781
OSI 744
OSI-774
R 1415
SR-05000001460
SR-05000001460-2
STK623143
Tarceva
UNII-J4T82NDH7E
ZINC01546066
[6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE
[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine
erlotinib
n-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine
nchembio866-comp3
3
MetforminapprovedPhase 1, Phase 21573657-24-9, 1115-70-414219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMBG
DMGG
Diabefagos
Diabetosan
Diabex
Diaformin
Dianben
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Meguan
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin Hydrochloride
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
Obimet
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
4
Bevacizumabapproved, investigationalPhase 21820216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
5Botulinum Toxins, Type APhase 2561
6Botulinum ToxinsPhase 2590
7
Progesteroneapproved47357-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE)CompletedNCT00628901Phase 4
2Randomized Pilot Study for the Treatment of Cutaneous Leiomyomas With Botulinum ToxinCompletedNCT00971620Phase 2
3A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell CancerRecruitingNCT01130519Phase 2
4Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell CarcinomaRecruitingNCT02495103Phase 1, Phase 2
5Comparison Study in the Treatment of Uterine Fibroids Uterine Fibroid Embolization Using BeadBlock™ Embolic AgentCompletedNCT00361036Phase 1
6Surgery for Intravenous LeiomyomatosisCompletedNCT01707862
7Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)CompletedNCT00001869
8Establishment of Fibroid Tissue BankCompletedNCT00710346
9Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal CancerRecruitingNCT00050752

Search NIH Clinical Center for Leiomyomatosis


Cochrane evidence based reviews: Leiomyomatosis

Genetic Tests for Leiomyomatosis

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Anatomical Context for Leiomyomatosis

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MalaCards organs/tissues related to Leiomyomatosis:

33
Uterus, Smooth muscle, Heart, Bone, Kidney, Lung, Small intestine

Animal Models for Leiomyomatosis or affiliated genes

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MGI Mouse Phenotypes related to Leiomyomatosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.5COL4A3, COL4A4, COL4A5, ESR1, FH, GNRH1
2MP:00053767.2COL4A3, COL4A4, COL4A5, ESR1, FH, GNRH1

Publications for Leiomyomatosis

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Articles related to Leiomyomatosis:

(show top 50)    (show all 581)
idTitleAuthorsYear
1
Single-stage operation using hypothermic circulatory arrest to remove uterine intravenous leiomyomatosis extended to the vena cava and right atrium. (25579748)
2015
2
Molecular Genetic Alterations in Renal Cell Carcinomas With Tubulocystic Pattern: Tubulocystic Renal Cell Carcinoma, Tubulocystic Renal Cell Carcinoma With Heterogenous Component and Familial Leiomyomatosis-associated Renal Cell Carcinoma. Clinicopathologic and Molecular Genetic Analysis of 15 Cases. (26447894)
2015
3
Leiomyomas beyond the uterus; benign metastasizing leiomyomatosis with paraaortic metastasizing endometriosis and intravenous leiomyomatosis: a case series and review of the literature. (25047270)
2014
4
Post-transplant diagnosis of hereditary leiomyomatosis and renal cell carcinoma syndrome in a kidney donor. (25859385)
2014
5
Uterine Intravenous Leiomyomatosis with Right Ventricular Extension. (24429697)
2014
6
eComment. Misdiagnosis of intravenous leiomyomatosis with cardiac extension. (23785088)
2013
7
Diffuse peritoneal leiomyomatosis. (23815223)
2013
8
Cutaneous clues to renal cell carcinoma: hereditary leiomyomatosis and renal cell carcinoma. (23652956)
2013
9
Management of intravascular leiomyomatosis: laparoscopic surgery for ordinary uterine fibroids led to an extraordinary finding. (23454251)
2013
10
A case of intravenous leiomyomatosis of uterine origin, extending through the inferior vena cava to right atrium. (22627954)
2013
11
Diffuse uterine leiomyomatosis in a child. (21710273)
2012
12
Intracardiac and intravenous leiomyomatosis. (23036637)
2012
13
Case 188: Intravenous leiomyomatosis with intracaval and intracardiac involvement. (23175549)
2012
14
Intravenous leiomyomatosis of the uterus with extension to the right heart. (21943238)
2011
15
Partial resection of intravenous leiomyomatosis with cardiac extension. (21225399)
2011
16
AIRP best cases in radiologic-pathologic correlation: intravenous leiomyomatosis. (21768238)
2011
17
Novel FH mutation in a patient with cutaneous leiomyomatosis associated with cutis verticis gyrata, eruptive collagenoma and Charcot-Marie-Tooth disease. (20560959)
2010
18
Intravenous leiomyomatosis with intracardiac extension: first reported case in Australia. (19423390)
2010
19
Type 2 segmental cutaneous leiomyomatosis: an example of mosaicism. (19109093)
2009
20
Leiomyomatosis of the esophagus: experience over a decade. (18818979)
2009
21
Wilms tumour as a possible early manifestation of hereditary leiomyomatosis and renal cell cancer? (19183174)
2009
22
Esophageal leiomyomatosis combined with intrathoracic stomach and gastric volvulus. (19793488)
2009
23
Successful management of a leiomyomatosis peritonealis disseminata with an aromatase inhibitor. (18669776)
2008
24
Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancer. (17287871)
2007
25
From gene to disease; cutaneous leiomyomatosis]. (17326474)
2007
26
Uterine plexiform leiomyomatosis with an intrinsic granulomatous response. (16581663)
2006
27
Type 2 segmental manifestation of cutaneous leiomyomatosis in four unrelated women with additional uterine leiomyomas (Reed's Syndrome). (16319483)
2006
28
Intravenous uterine leiomyomatosis with right heart extension: successful two-stage surgical removal. (16583249)
2006
29
Missense mutations in fumarate hydratase in multiple cutaneous and uterine leiomyomatosis and renal cell cancer. (16237213)
2005
30
Pre- and postoperative MRI of esophageal and gastric leiomyomatosis in a pediatric patient. (15728005)
2005
31
Hereditary leiomyomatosis associated with bilateral, massive, macronodular adrenocortical disease and atypical cushing syndrome: a clinical and molecular genetic investigation. (15741255)
2005
32
Esophageal leiomyomatosis diagnosed by endoscopic ultrasound. (15731952)
2005
33
Successful one-stage radical removal of intravenous leiomyomatosis extending to the right ventricle. (15121610)
2004
34
Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas. (12177782)
2002
35
Ovarian endometriosis and clear cell carcinoma, leiomyomatosis peritonealis disseminata, and endometrial adenocarcinoma: an unusual, pathogenetically related association. (11444203)
2001
36
Late intracaval and intracardiac leiomyomatosis following hysterectomy for benign myomas treated by surgery and GnRH agonist. (11606110)
2001
37
Diffuse esophageal leiomyomatosis: another cause of pseudoachalasia. (14601910)
2000
38
Diffuse leiomyomatosis of the uterus: a case report with clonality analysis. (11112221)
2000
39
Intravenous leiomyomatosis with caval involvement: report of a case with radical resection and venous replacement. (9565130)
1998
40
Topoisomerase I and II consensus sequences in a 17-kb deletion junction of the COL4A5 and COL4A6 genes and immunohistochemical analysis of esophageal leiomyomatosis associated with Alport syndrome. (9463311)
1998
41
Diffuse leiomyomatosis of the oesophagus--a case report. (9601829)
1998
42
Leiomyomatosis peritonealis disseminata occurring in a postmenopausal woman: report of a case. (8883241)
1996
43
Leiomyomatosis peritonealis disseminata. Two case reports. (8758301)
1996
44
Leuprolide acetate and intravascular leiomyomatosis. (7675416)
1995
45
Leiomyomatosis peritonealis disseminata. A report of two cases. (7996533)
1994
46
High-output cardiac failure: an unusual manifestation of intravenous leiomyomatosis. (8456404)
1993
47
Leiomyomatosis peritonealis disseminata. (3061357)
1988
48
Recurrent pelvic intravenous leiomyomatosis. (7465135)
1981
49
Intravenous leiomyomatosis of the uterus with extension into the heart. (7416191)
1980
50
Intravenous leiomyomatosis of the uterus. A report of four cases. (13904785)
1961

Variations for Leiomyomatosis

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Cosmic variations for Leiomyomatosis:

7 (show all 45)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1690METkidney,NS,carcinoma,papillary renal cell carcinoma3
2704METkidney,NS,carcinoma,papillary renal cell carcinoma3
3698METkidney,NS,carcinoma,papillary renal cell carcinoma3
4689METkidney,NS,carcinoma,papillary renal cell carcinoma3
5484661METkidney,NS,carcinoma,papillary renal cell carcinoma3
6697METkidney,NS,carcinoma,papillary renal cell carcinoma3
7696METkidney,NS,carcinoma,papillary renal cell carcinoma3
8688METkidney,NS,carcinoma,papillary renal cell carcinoma3
9691METkidney,NS,carcinoma,papillary renal cell carcinoma3
1017807VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1114311VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1218346VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1317808VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1430286VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1525673VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1610709TP53kidney,NS,carcinoma,papillary renal cell carcinoma3
1743697TP53kidney,NS,carcinoma,papillary renal cell carcinoma3
1843850TP53kidney,NS,carcinoma,papillary renal cell carcinoma3
19718FGFR3kidney,NS,carcinoma,papillary renal cell carcinoma3
203993568FGFR3kidney,NS,carcinoma,papillary renal cell carcinoma3
21760PIK3CAkidney,NS,carcinoma,papillary renal cell carcinoma3
22763PIK3CAkidney,NS,carcinoma,papillary renal cell carcinoma3
23462BRAFkidney,NS,carcinoma,papillary renal cell carcinoma3
241131BRAFkidney,NS,carcinoma,papillary renal cell carcinoma3
25375284ANKHD1kidney,NS,carcinoma,papillary renal cell carcinoma3
26110414SMARCB1kidney,NS,carcinoma,papillary renal cell carcinoma3
27375283ANKHD1-EIF4EBP3kidney,NS,carcinoma,papillary renal cell carcinoma3
281268384TP63kidney,NS,carcinoma,papillary renal cell carcinoma3
291181978ADARB1kidney,NS,carcinoma,papillary renal cell carcinoma3
30487039SCAIkidney,NS,carcinoma,papillary renal cell carcinoma3
31964299MAP2K5kidney,NS,carcinoma,papillary renal cell carcinoma3
32274461CDC73kidney,NS,carcinoma,papillary renal cell carcinoma3
33742462GFRALkidney,NS,carcinoma,papillary renal cell carcinoma3
34188258HIVEP3kidney,NS,carcinoma,papillary renal cell carcinoma3
35485065RHEBkidney,NS,carcinoma,papillary renal cell carcinoma3
3621945EGFRkidney,NS,carcinoma,papillary renal cell carcinoma3
371583146DNMT3Akidney,NS,carcinoma,papillary renal cell carcinoma3
38485575PMS2P11kidney,NS,carcinoma,papillary renal cell carcinoma3
395260PTENkidney,NS,carcinoma,papillary renal cell carcinoma3
40521KRASkidney,NS,carcinoma,papillary renal cell carcinoma3
41302052DHX9kidney,NS,carcinoma,papillary renal cell carcinoma3
4214060ERBB2kidney,NS,carcinoma,papillary renal cell carcinoma3
43163384PDGFRAkidney,NS,carcinoma,papillary renal cell carcinoma3
441360764SOX5kidney,NS,carcinoma,papillary renal cell carcinoma3
451222993RAD23Bkidney,NS,carcinoma,papillary renal cell carcinoma3

Expression for genes affiliated with Leiomyomatosis

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Search GEO for disease gene expression data for Leiomyomatosis.

Pathways for genes affiliated with Leiomyomatosis

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Pathways related to Leiomyomatosis according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
18.8COL4A3, COL4A4, COL4A5
28.5COL4A3, COL4A4, COL4A5, COL4A6
3
Show member pathways
8.5COL4A3, COL4A4, COL4A5, COL4A6
4
Show member pathways
8.5COL4A3, COL4A4, COL4A5, COL4A6
5
Show member pathways
8.5COL4A3, COL4A4, COL4A5, COL4A6
68.5COL4A3, COL4A4, COL4A5, COL4A6
78.5COL4A3, COL4A4, COL4A5, COL4A6
88.5COL4A3, COL4A4, COL4A5, COL4A6
98.5COL4A3, COL4A4, COL4A5, COL4A6
108.5COL4A3, COL4A4, COL4A5, COL4A6
118.5COL4A3, COL4A4, COL4A5, COL4A6
12
Show member pathways
8.5COL4A3, COL4A4, COL4A5, COL4A6
138.2COL4A3, COL4A4, COL4A5, COL4A6, FH
14
Show member pathways
8.0COL4A3, COL4A4, COL4A5, COL4A6, GNRH1

GO Terms for genes affiliated with Leiomyomatosis

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Cellular components related to Leiomyomatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1basal laminaGO:000560510.1COL4A4, COL4A5
2collagen trimerGO:00055818.5COL4A3, COL4A4, COL4A5, COL4A6
3endoplasmic reticulum lumenGO:00057888.5COL4A3, COL4A4, COL4A5, COL4A6
4collagen type IV trimerGO:00055878.4COL4A3, COL4A4, COL4A5, COL4A6
5basement membraneGO:00056048.2COL4A3, COL4A4, COL4A5, COL4A6

Biological processes related to Leiomyomatosis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1tricarboxylic acid cycleGO:000609910.2FH, SDHB
2intracellular steroid hormone receptor signaling pathwayGO:00305189.9ESR1, MED12
3glomerular basement membrane developmentGO:00328369.6COL4A3, COL4A4
4transcription initiation from RNA polymerase II promoterGO:00063679.5ESR1, MED12, PGR
5extracellular matrix disassemblyGO:00226178.5COL4A3, COL4A4, COL4A5, COL4A6
6extracellular matrix organizationGO:00301988.5COL4A3, COL4A4, COL4A5, COL4A6
7collagen catabolic processGO:00305748.2COL4A3, COL4A4, COL4A5, COL4A6

Molecular functions related to Leiomyomatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingGO:000487910.0ESR1, PGR
2steroid bindingGO:00054969.8ESR1, PGR
3extracellular matrix structural constituentGO:00052018.5COL4A3, COL4A4, COL4A5, COL4A6

Sources for Leiomyomatosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet