MCID: LNS001
MIFTS: 31

Lens Subluxation malady

Category: Eye diseases

Aliases & Classifications for Lens Subluxation

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Aliases & Descriptions for Lens Subluxation:

Name: Lens Subluxation 11 49 38 13 67
 
Subluxation of Lens 11 26

Classifications:



External Ids:

Disease Ontology11 DOID:11364
ICD1029 H27.11
ICD9CM31 379.32
MeSH38 D007906
NCIt44 C34772

Summaries for Lens Subluxation

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Wikipedia:70 Ectopia lentis is a displacement or malposition of the eye\'s crystalline lens from its normal location.... more...

MalaCards based summary: Lens Subluxation, also known as subluxation of lens, is related to isolated ectopia lentis and myopia, high, with cataract and vitreoretinal degeneration. An important gene associated with Lens Subluxation is FBN1 (Fibrillin 1), and among its related pathways are Carbon metabolism and One carbon pool by folate. Affiliated tissues include eye and endothelial.

Related Diseases for Lens Subluxation

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Graphical network of the top 20 diseases related to Lens Subluxation:



Diseases related to lens subluxation

Symptoms for Lens Subluxation

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Drugs & Therapeutics for Lens Subluxation

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Prospective Study of Cionni Ring and In-the-bag IOL Implantation for Subluxated LensesCompletedNCT01346566Phase 3
2Comparison of the Capsular Stability With Two Different IOL Models in Patients With Pseudoexfoliation Syndrome: an Exploratory StudyUnknown statusNCT02155478
3Ultrasound Biomicroscopic Analysis of Cionni Ring and In-the-bag IOL Implantation for Subluxated LensesCompletedNCT02790268
4Early Vs Late Post Traumatic Cataract SurgeryCompletedNCT02900365
5Late Dislocation of Intraocular Lens (IOL) Following Cataract Surgery: an Evaluation of Two Different Surgical MethodsActive, not recruitingNCT01784926
6Endothelial Cell Loss After Phacoemulsification Intra and SupracapsularActive, not recruitingNCT02535819
7Natural History of IOL in Pseudo Exfoliation SyndromeActive, not recruitingNCT01255995

Search NIH Clinical Center for Lens Subluxation


Cochrane evidence based reviews: lens subluxation

Genetic Tests for Lens Subluxation

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Genetic tests related to Lens Subluxation:

id Genetic test Affiliating Genes
1 Lens Subluxation26

Anatomical Context for Lens Subluxation

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MalaCards organs/tissues related to Lens Subluxation:

35
Eye, Endothelial

Animal Models for Lens Subluxation or affiliated genes

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Publications for Lens Subluxation

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Articles related to Lens Subluxation:

(show top 50)    (show all 64)
idTitleAuthorsYear
1
Homocysteinemia due to MTHFR deficiency in a young adult presenting with bilateral lens subluxations. (27046515)
2016
2
Unilateral fronto-temporal headache with ocular pain caused by lens subluxation due to spontaneous zonulysis. (27752586)
2015
3
Single suture iris-to-capsulorhexis fixation for in-the-bag intraocular lens subluxation. (26703481)
2015
4
Pathologic evidence of pseudoexfoliation in cases of in-the-bag intraocular lens subluxation or dislocation. (25935341)
2015
5
Recessive mutations in LEPREL1 underlie a recognizable lens subluxation phenotype. (25469533)
2015
6
Surgical management of lens subluxation in Marfan syndrome. (24698610)
2014
7
Multiple methods of surgical treatment combined with primary IOL implantation on traumatic lens subluxation/dislocation in patients with secondary glaucoma. (24790868)
2014
8
Results of fibrillin-1 gene analysis in children from inbred families with lens subluxation. (24698609)
2014
9
Lens Subluxation after Plasmin and SF6 Injections in Rabbit Eyes. (25397749)
2014
10
Intraocular lens subluxation in marfan syndrome. (25279020)
2014
11
Traumatic lens subluxation presenting as pseudomelanoma. (25127532)
2014
12
A case of Alagille syndrome complicated by intraocular lens subluxation and rhegmatogenous retinal detachment. (23898221)
2013
13
Traumatic in-the-bag intraocular lens subluxation. (24088929)
2013
14
Lens subluxation with stretched ciliary processes in a girl with Goltz syndrome. (24923086)
2013
15
Lens Subluxation and Retinal Dysfunction in a Girl with Homozygous VSX2 Mutation. (24001013)
2013
16
Scleral fixation of standard capsular tension ring and in-the-bag intraocular lens implantation in patients with severe lens subluxation. (23053778)
2012
17
Ocular photography contest. Grand prize: anterior segment: Crystalline lens subluxation with intact zonules in patient with Marfana89s syndrome. (23281527)
2012
18
Pentacam-aided diagnosis of traumatic lens subluxation. (22491583)
2012
19
Comparison of clinical outcomes between iris-fixated anterior chamber intraocular lenses and scleral-fixated posterior chamber intraocular lenses in Marfan syndrome with lens subluxation. (21668788)
2012
20
Congenital ocular malformations (lens subluxation, pupillary displacement, cataract, myopia) and classic galactosaemia associated with Q188R anda88/or G1391A mutations. (20222886)
2011
21
Late capsular bag contraction and intraocular lens subluxation in retinitis pigmentosa: a case report. (21320335)
2011
22
Red reflex mimicking lens subluxation in a child undergoing orthokeratology. (19300465)
2010
23
Treatment of severe crystalline lens subluxation. (20457402)
2010
24
Management of traumatic crystalline lens subluxation and dislocation. (20057305)
2010
25
Chronic newborn primary congenital glaucoma with secondary lens subluxation. (19645394)
2009
26
Primary anterior chamber intraocular lens for the treatment of severe crystalline lens subluxation. (19781480)
2009
27
Phacoemulsification using iris hooks and scleral fixation of the intraocular lens in patients with secondary glaucoma associated with lens subluxation. (17585310)
2008
28
Bilateral intraocular lens subluxation secondary to haptic angulation. (18361996)
2008
29
Bilateral lens subluxation in a case of lipoid proteinosis. (17662444)
2007
30
Anterior axial lens subluxation, progressive myopia, and angle-closure glaucoma: recognition and treatment of atypical presentation of ectopia lentis. (16935236)
2006
31
Iridoschisis associated with lens subluxation. (15342034)
2004
32
Iridoschisis and bilateral lens subluxation associated with periocular eczema. (14967294)
2004
33
Spontaneous, late, in-the-bag intraocular lens subluxation in a patient with a previous acute angle-closure glaucoma attack. (15313313)
2004
34
Lens subluxation following contact transscleral cyclodiode. (12365925)
2002
35
Lens subluxation: 10-years' experience at Chang Gung Memorial Hospital, Kaohsiung. (11858394)
2001
36
Intraocular lens subluxation in a patient with facial atopic dermatitis. (11226805)
2001
37
Iridoschisis associated with lens subluxation. (11738924)
2001
38
Secondary glaucoma associated with crystalline lens subluxation. (11033403)
2000
39
Marfan syndrome, lens subluxation, and open-angle glaucoma. (10604300)
1999
40
Contusion [correction of Confusion] and lens subluxation. (9591965)
1998
41
Bilateral megalocornea with unilateral lens subluxation. (9134548)
1997
42
Spontaneous lens subluxation in uveitis. (2248347)
1990
43
Detection of lens subluxation in pseudoexfoliation. (3261163)
1988
44
Monocular oscillopsia secondary to lens subluxation. (3491579)
1986
45
Lens subluxation in homocystinuria. A case report. (6331704)
1984
46
Anterior chamber lens subluxation through a basal peripheral iridectomy. (6682848)
1983
47
Superior lens subluxation. (528348)
1979
48
Lens subluxation and surgical aphakia treated with photocoagulation of the iris. (5359558)
1969
49
Lens subluxation or dislocation into the vitreous after a cataract incision. (20344406)
1947
50
Extraction of Right Dislocated Lens; Subluxation of Left Lens, which shows Suspensory Ligament. (19981312)
1920

Variations for Lens Subluxation

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Expression for genes affiliated with Lens Subluxation

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Search GEO for disease gene expression data for Lens Subluxation.

Pathways for genes affiliated with Lens Subluxation

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GO Terms for genes affiliated with Lens Subluxation

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Cellular components related to Lens Subluxation according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:00056049.4FBN1, P3H2

Biological processes related to Lens Subluxation according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1homocysteine metabolic processGO:00506678.8CBS, MTHFR
2oxidation-reduction processGO:00551148.5CBS, MTHFR, P3H2

Molecular functions related to Lens Subluxation according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1modified amino acid bindingGO:00723419.1CBS, MTHFR

Sources for Lens Subluxation

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet