MCID: LPR003
MIFTS: 71

Leprosy malady

Categories: Genetic diseases, Infectious diseases, Neuronal diseases, Reproductive diseases, Rare diseases, Eye diseases, Skin diseases

Aliases & Classifications for Leprosy

About this section
Sources:
49OMIM, 10Disease Ontology, 12DISEASES, 51Orphanet, 36MeSH, 2CDC, 65UMLS, 11diseasecard, 24GTR, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Leprosy:

Name: Leprosy 49 10 12 51 36 2 65
Leprosy, Susceptibility to 11
 
Leprosy 2 24
Leprosy 3 24

Characteristics:

Orphanet epidemiological data:

51
leprosy:
Inheritance: Multigenic/multifactorial; Prevalence: 1-9/100000 (Worldwide); Age of onset: All ages; Age of death: any age


Classifications:



External Ids:

Disease Ontology10 DOID:1024
ICD1027 A30, A30.9
ICD9CM29 030, 030.9
MeSH36 D007918
NCIt42 C84824
Orphanet51 548
ICD10 via Orphanet28 A30.0, A30.1, A30.2 A30.3, A30.4, A30.5, A30.8, A30.9, more
MESH via Orphanet37 D007918
UMLS via Orphanet66 C0023343
UMLS65 C0023343

Summaries for Leprosy

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Disease Ontology:10 A primary bacterial infectious disease that results in infection located in superficial peripheral nerves, located in skin, located in mucous membranes of the upper respiratory tract, located in anterior chamber of the eyes, or located in testes, has material basis in Mycobacterium leprae, which is transmitted by aerosol spread from infected nasal secretions to exposed nasal and oral mucosa. The infection has symptom skin lesions, has symptom sensory loss, has symptom motor loss and has symptom eye damage.

MalaCards based summary: Leprosy, also known as leprosy, susceptibility to, is related to tuberculoid leprosy and buruli ulcer, and has symptoms including skin lesions, sensory loss and motor loss. An important gene associated with Leprosy is TLR2 (Toll Like Receptor 2), and among its related pathways are Phagocytosis of Microbes and Rheumatoid arthritis. The drug thalidomide has been mentioned in the context of this disorder. Affiliated tissues include superficial peripheral nerves, skin and mucous membranes of the upper respiratory tract, and related mouse phenotypes are tumorigenesis and liver/biliary system.

Wikipedia:68 Leprosy, also known as Hansen\'s disease (HD), is a long term infection caused by the bacteria... more...

Descriptions from OMIM:49 246300,607572

Related Diseases for Leprosy

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Diseases in the Leprosy family:

Leprosy 5 Leprosy 4

Diseases related to Leprosy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 396)
idRelated DiseaseScoreTop Affiliating Genes
1tuberculoid leprosy34.6IFNG, SLC11A1, TLR2, TNF
2buruli ulcer30.6IFNG, IL10, IL4, SLC11A1
3hemolytic anemia30.3IFNG, IL10, TNF
4porphyria30.2IFNG, LTA, SLC11A1, TNF
5atopy30.0IFNG, IL10, IL12RB2, IL4, TLR2
6mycosis fungoides30.0IFNG, IL10, IL2, IL4, TNF
7cutaneous leishmaniasis29.6IFNG, IL10, IL12RB2, IL18RAP, NOD2, SLC11A1
8cryptococcosis29.6IFNG, IL10, IL4
9systemic lupus erythematosus29.1CD40LG, IFNG, IL10, IL2, LTA, TNF
10malaria28.3CD40LG, IFNG, IL10, IL2, IL4, LTA
11rheumatoid arthritis28.2CD40LG, IFNG, IL10, IL2, IL4, SLC11A1
12lepromatous leprosy12.5
13borderline leprosy12.4
14indeterminate leprosy12.4
15leprosy 512.1
16leprosy 411.9
17hansen's disease11.6
18neutropenia chronic familial10.9TLR1, TLR2
19punctate palmoplantar keratoderma type 210.9IL10, TNF
20noonan-like/multiple giant cell lesion syndrome10.8SLC11A1, TLR2, TNF
21ureterocele10.8IL2, TNF
22drug-induced mental disorder10.8IL10, LTA, TNF
23ethmoid sinus squamous cell carcinoma10.8IFNG, SLC11A1, TNF
24prostate transitional cell carcinoma10.8IL10, SLC11A1, TNF
25malignant sertoli-leydig cell tumor of ovary10.8LTA, TNF
26keshan disease10.8IFNG, TLR1, TLR2
27autoimmune oophoritis10.8IFNG, TNF
28cholera10.8IL10, TLR2, TNF
29multifocal lymphangioendotheliomatosis with thrombocytopenia10.8IL10, TNF
30celiac disease 1210.8PACRG, PARK2
31legionellosis10.8IFNG, LTA, TLR1
32trachoma10.7IL10, TLR2, TNF
33opisthorchiasis10.7IFNG, IL10, TNF
34parovarian cyst10.7IL2, TLR2, TNF
35hypercementosis10.7IFNG, IL10, TNF
36hydronephrosis10.7IFNG, IL10, TNF
37meningitis10.7IL10, TLR2, TNF
38cytoplasmic body myopathy10.7IFNG, IL10, TNF
39dancing eyes-dancing feet syndrome10.7IFNG, IL10, TNF
40peripheral retinal degeneration10.7IFNG, IL10, TNF
41primary progressive freezing gait10.7IL10, IL4, TNF
42tracheal stenosis10.7IFNG, IL10, TNF
43melioidosis10.7NOD2, TLR1, TLR2
44pustulosis of palm and sole10.7NOD2, TNF
45kearns-sayre syndrome10.7IL10, IL4, TNF
46lung lymphoma10.7LTA, SLC11A1, TNF
47spondylocamptodactyly10.7LTA, NOD2, TNF
48ileocolitis10.7NOD2, TLR2, TNF
49precursor b lymphoblastic lymphoma/leukemia10.7IL10, LTA, SLC11A1, TNF
50graft-versus-host disease, protection against10.7IFNG, IL10, IL2

Comorbidity relations with Leprosy via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Leprosy:



Diseases related to leprosy

Symptoms for Leprosy

About this section

Symptoms by clinical synopsis from OMIM:

246300

Clinical features from OMIM:

246300,607572

Symptoms:

 10
  • skin lesions
  • sensory loss
  • motor loss
  • eye damage

HPO human phenotypes related to Leprosy:

id Description Frequency HPO Source Accession
1 abnormality of the immune system HP:0002715

Drugs & Therapeutics for Leprosy

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Drugs for Leprosy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 119)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dapsoneapproved, investigationalPhase 4, Phase 1, Phase 26280-08-02955
Synonyms:
(4-sulfanilylphenyl)amine
1,1'-Sulfonylbis(4-aminobenzene)
1,1'-Sulfonylbis[4-aminobenzene]
1,1'-Sulphonylbis(4-aminobenzene)
1358F
32960_FLUKA
4,4' Diaminophenyl Sulfone
4,4'-Dapsone
4,4'-Diaminodiphenyl sulfone
4,4'-Diaminodiphenyl sulphone
4,4'-Diaminodiphenyl suphone
4,4'-Diaminodiphenylsulfone
4,4'-Sulfonylbisaniline
4,4'-Sulfonylbisbenzamine
4,4'-Sulfonylbisbenzenamine
4,4'-Sulfonylbisbenzeneamine
4,4'-Sulfonyldianilin
4,4'-Sulfonyldianiline
4,4'-Sulfonyldianiline (Dapsone)
4,4'-Sulphonylbisbenzamine
4,4'-Sulphonylbisbenzenamine
4,4'-Sulphonyldianiline
4,4'-diaminophenyl sulfone
4,4'-sulfonyldianiline
4,4-Diaminodifenylsulfon
4,4-Diaminodifenylsulfon [Czech]
4,4-Sulfonyldianiline
4-(4-Aminophenylsulfonyl)aniline
4-(4-Aminophenylsulfonyl)benzenamine
4-(4-amino-Benzenesulfonyl)-phenylamine
4-(4-aminophenyl)sulfonylaniline
4-Aminop henyl sulfone
4-Aminophenyl sulfone
4-Aminophenylsulfone
4-[(4-aminobenzene)sulfonyl]aniline
4-[(4-aminophenyl)sulfonyl]aniline
46158_FLUKA
46158_RIEDEL
80-08-0
A74807_ALDRICH
AB00051962
AB1004833
AC-10922
AC1L1EUH
AC1Q51WM
AC1Q51WN
AI3-08087
AKOS000119322
ALBB-005917
AZT + Dapsone cominbation
Acedapsone
Aczone
Aczone (TN)
Ambap80-08-0
Araldite HT
Araldite HT 976
Araldite Ht
Atrisone
Avlosulfon
Avlosulfone
Avlosulphone
Avsulfor
BIDD:GT0770
BPBio1_000143
BRD-K62363391-001-05-8
BRN 0788055
BSPBio_000129
BSPBio_002129
Bis(4-aminophenyl) sulfone
Bis(4-aminophenyl)sulfone
Bis(4-aminophenyl)sulphone
Bis(P-aminophenyl) sulfone
Bis(p-aminophenyl) sulfone
Bis(p-aminophenyl)sulphone
C07666
CAS-80-08-0
CBDivE_013582
CCRIS 192
CHEBI:4325
CHEMBL1043
CID2955
CPD000059064
Croysulfone
Croysulphone
D SS
D003622
D00592
D0089
DADPS
DAPSONE
DB00250
DDS
DDS (pharmaceutical)
DDS, diaphenylsulfone
DDS, pharmaceutical
DIAPHENYLSULFONE
DSS
DSS (VAN)
Dapsoderm-X
Dapson
Dapson-Fatol
Dapsona
Dapsona [INN-Spanish]
Dapsone
Dapsone (USP)
Dapsone [USAN:BAN]
Dapsonum
Dapsonum [INN-Latin]
Dds, Diaphenylsulfone
Dds, Pharmaceutical
Di(4-aminophenyl) sulfone
Di(4-aminophenyl)sulfone
Di(4-aminophenyl)sulphone
Di(p-aminophenyl) sulfone
Di(p-aminophenyl)sulphone
Diamino-4,4'-diphenyl sulfone
Diamino-4,4'-diphenyl sulphone
Diamino-diphenyl sulphone
Diaminodifenilsulfona
Diaminodifenilsulfona [Spanish]
Diaminodiphenyl Sulfone
Diaminodiphenyl sulfone
Diaminodiphenylsulfone
Diaphenylsulfon
 
Diaphenylsulfone
Diaphenylsulfone (JAN)
Diaphenylsulphon
Diaphenylsulphone
Dimitone
Diphenasone
Diphone
Disulone
DivK1c_000573
Dubronax
Dubronaz
Dumitone
EINECS 201-248-4
Eporal
F 1358
Fatol Brand of Dapsone
HMS1568G11
HMS1920C14
HMS2091K04
HMS501M15
HSDB 5073
HT 976
HY 976
Hardener HT 976
I01-3640
ICI
IDI1_000573
IN-201
KBio1_000573
KBio2_001368
KBio2_003936
KBio2_006504
KBio3_001349
KBioGR_000900
KBioSS_001368
LS-1790
MLS000069409
MLS001055349
MLS001076146
Metabolite C
Mex-America Brand of Dapsone
MolPort-001-780-172
N, N'-Diphenyl Sulfondiamide
N, N'-Diphenyl sulfondiamide
N,N'-Diphenyl sulfondiamide
NCGC00016322-01
NCGC00016322-02
NCGC00023946-03
NCGC00023946-04
NCGC00023946-05
NCGC00023946-06
NCI-C01718
NINDS_000573
NSC 6091
NSC 6091D
NSC-6091
NSC6091
Normet
Novophone
Oprea1_143052
Orsade Brand of Dapsone
P, P'-Sulfonyldianiline
P,P'-Diaminodiphenyl Sulfone
P,P'-diaminodiphenyl sulfone
P,P-Diaminodiphenyl Sulphone
P,P-Sulfonylbisbenzamine
P,P-Sulfonylbisbenzenamine
P,P-Sulphonylbisbenzamine
P,P-Sulphonylbisbenzenamine
P,P-Sulphonyldianiline
P-Aminophenyl Sulfone
P-Aminophenyl sulfone
Prestwick0_000035
Prestwick1_000035
Prestwick2_000035
Prestwick3_000035
Prestwick_152
Protogen
Recolip
SAM002554879
SMR000059064
SPBio_001025
SPBio_002050
SPECTRUM1500222
STK387118
Spectrum2_001133
Spectrum3_000375
Spectrum4_000310
Spectrum5_000825
Spectrum_000888
Sulfadione
Sulfanona-Mae
Sulfanona-mae
Sulfon-Mere
Sulfon-mere
Sulfona
Sulfona-MAE
Sulfona-Mae
Sulfone Ucb
Sulfone ucb
Sulfone, 4,4'-Diaminophenyl
Sulfonyldianiline
Sulphadione
Sulphon-Mere
Sulphon-mere
Sulphonyldianiline
Sumicure S
TL8005401
Tarimyl
UNII-8W5C518302
Udolac
W R 448
WLN: ZR DSWR DZ
WR 448
ZINC00006310
dapsone
p, p'-Sulfonyldianiline
p,p'-Diaminodiphenyl sulfone
p,p'-sulfonyldianiline
p,p-Diaminodiphenyl sulphone
p,p-Sulfonylbisbenzamine
p,p-Sulfonylbisbenzenamine
p,p-Sulphonylbisbenzamine
p,p-Sulphonylbisbenzenamine
p,p-Sulphonyldianiline
p-Aminophenyl sulfone
2
IsoniazidapprovedPhase 4, Phase 114254-85-33767
Synonyms:
37271-10-6
4-pyridinecarbohydrazide
41466-07-3
5015 R.P
5015 R.P.
5015 RP
54-85-3
62229-51-0
7640-37-1
AB00052025
AC1L1GNZ
AC1Q54UP
AC1Q54UQ
AI3-23936
AKOS000119062
AZT + Isoniazid
Abdizide
Andrazide
Anidrasona
Antimicina
Antituberkulosum
Armacide
Armazid
Armazide
Atcotibine
Azuren
BB_SC-6246
BIDD:GT0140
BP 5015
BPBio1_000025
BPBio1_001322
BSPBio_000021
BSPBio_002204
Bacillin
Biomol-NT_000288
C07054
C6H7N3O
CAS-54-85-3
CCRIS 351
CHEBI:6030
CHEMBL64
CID3767
CPD000059082
Cedin
Cedin (Aerosol)
Cemidon
Chemiazid
Chemidon
Continazine
Cortinazine
Cotinazin
Cotinizin
D00346
D007538
DB00951
Defonin
Dibutin
Diforin
Dinacrin
Ditubin
DivK1c_000070
Dow-Isoniazid
EINECS 200-214-6
Ebidene
Eralon
Ertuban
Eutizon
Evalon
FRS-3
FSR 3
FSR-3
Fetefu
Fimalene
GINK
HIA
HMS1568B03
HMS1920H09
HMS2089I16
HMS2091N19
HMS500D12
HSDB 1647
Hid rasonil
Hidranizil
Hidrasonil
Hidrulta
Hidrun
Hycozid
Hydra
Hydrazid
Hydrazide
Hyozid
Hyzyd
I.A.I
I.A.I.
I0138
I14-9731
I3377_FLUKA
I3377_SIGMA
IDI1_000070
INH
INHd20
Ido-tebin
Idrazil
In-73
Inah
Inh-Burgthal
Inizid
Iscotin
Isidrina
Ismazide
Isobicina
Isocid
Isocidene
Isocotin
Isohydrazide
Isokin
Isolyn
Isonerit
Isonex
Isoniacid
Isoniazid
Isoniazid & EEP
Isoniazid & Propolis
Isoniazid SA
Isoniazida
Isoniazide
Isoniazidum
Isonicazide
Isonicid
Isonico
Isonicotan
Isonicotil
Isonicotinhydrazid
Isonicotinic acid hydrazide
Isonicotinic hydrazide
Isonicotinohydrazide
Isonicotinoyl hydrazide
Isonicotinoylhydrazide
Isonicotinsaeurehydrazid
Isonicotinyl hydrazide
Isonicotinyl hydrazine
Isonicotinylhydrazine
Isonide
Isonidrin
Isonikazid
Isonilex
Isonin
Isonindon
Isonirit
Isoniton
Isonizida
Isonizide
Isopyrin
 
Isotamine
Isotebe
Isotebezid
Isotinyl
Isozid
Isozide
Isozyd
KBio1_000070
KBio2_001333
KBio2_003901
KBio2_006469
KBio3_001424
KBioGR_000423
KBioSS_001333
L 1945
LANIZID
LS-205
Laniazid
Laniazid (TN)
Laniozid
MLS000069444
MLS001055327
MolPort-000-141-557
Mybasan
NCGC00016244-01
NCGC00016244-02
NCGC00022648-03
NCGC00022648-04
NCGC00022648-05
NCGC00022648-06
NINDS_000070
NSC 9659
NSC9659
Neo-Tizide
Neoteben
Neoxin
Neumandin
Nevin
Niadrin
Nicazide
Nicetal
Nicizina
Niconyl
Nicotibina
Nicotibine
Nicotisan
Nicozide
Nidaton
Nidrazid
Nikozid
Niplen
Nitadon
Niteban
Nitebannsc 9659
Nydrazid
Nyscozid
Oprea1_396155
Pelazid
Percin
Phthisen
Preparation 6424
Prestwick0_000161
Prestwick1_000161
Prestwick2_000161
Prestwick3_000161
Prestwick_578
Pycazide
Pyreazid
Pyricidin
Pyridicin
Pyridine-4-carboxylic acid hydrazide
Pyrizidin
RP 5015
RP-5015
RU-EF-Tb
RY-EF-Tb
Raumanon
Razide
Retozide
Rifamate
Rimicid
Rimifon
Rimiphone
Rimitsid
Robiselin
Robisellin
Roxifen
S1937_Selleck
SAM002554904
SMR000059082
SPBio_000094
SPBio_001942
SPECTRUM1500355
STK086288
Sanohidrazina
Sauterazid
Sauterzid
Spectrum2_000107
Spectrum3_000472
Spectrum4_000022
Spectrum5_000876
Spectrum_000853
Stanozide
TB-Phlogin
TB-Razide
TB-Vis
Tebecid
Tebenic
Tebexin
Tebilon
Tebos
Teebaconin
Tekazin
Tibazide
Tibemid
Tibiazide
Tibinide
Tibison
Tibivis
Tibizide
Tibusan
Tisin
Tisiodrazida
Tizide
Tubazid
Tubazide
Tubeco
Tubecotubercid
Tuberian
Tubicon
Tubilysin
Tubizid
Tubomel
Tyvid
UNII-V83O1VOZ8L
Unicocyde
Unicozyde
Usaf cb-2
Vazadrine
Vederon
WLN: T6NJ DVMZ
ZINC00001590
Zidafimia
Zinadon
Zonazide
bacillen
bp 5 015
isoco tin
isoniazid
isozid e
nchembio884-comp3
nidra zid
rimif on
tebemid
tubercid
3
Clofazimineapproved, investigationalPhase 4, Phase 1, Phase 2212030-63-92794
Synonyms:
(3Z)-N,5-bis(4-chlorophenyl)-3-[(1-methylethyl)imino]-3,5-dihydrophenazin-2-amine
2030-63-9
3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine
3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin
3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin [German]
3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
4-25-00-03033 (Beilstein Handbook Reference)
AC1L1EHE
B 663
B 663 (Pharmaceutical)
B 663 (VAN)
B 663, pharmaceutical
B-663
B. 663
B663
BIDD:PXR0147
BPBio1_000585
BRN 0060420
BSPBio_000531
C06915
C27H22Cl2N4
C8895_SIGMA
CAS-2030-63-9
CFZ
CHEBI:3749
CHEBI:730395
CHEMBL1083384
CHEMBL1292
CID2794
CPD000058704
Chlofazimine
Clofazimin
Clofazimina
Clofazimina [INN-Spanish]
Clofazimine
Clofazimine (JAN/USP/INN)
Clofazimine [USAN:INN:BAN]
Clofaziminum
Clofaziminum [INN-Latin]
 
D00278
DB00845
EINECS 217-980-2
G 30320
G-30,320
G-30320
HMS1569K13
HMS2052B05
HMS2093J10
I06-1891
LS-103014
Lampren
Lamprene
Lamprene (TN)
Liposome-encapsulated clofazimine
MLS000028617
MLS001424318
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(1-methylethyl)imino)-2-phenazinamine
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine
N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine
NCGC00016600-01
NCGC00016600-02
NCGC00179529-01
NSC 141046
NSC-141046
NSC141046
Prestwick0_000376
Prestwick1_000376
Prestwick2_000376
Prestwick3_000376
Prestwick_685
Riminophenazine
SAM001246878
SMP2_000339
SMR000058704
SPBio_002452
ST51014966
UNII-D959AE5USF
clofazimine
4
RifampicinapprovedPhase 4, Phase 2, Phase 3, Phase 130313292-46-15458213, 5381226
Synonyms:
1-b]furan-21-yl acetate
13292-46-1
3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin sv
3-(4-Methylpiperazinyliminomethyl)-rifamycin SV
3-(4-Methylpiperazinyliminomethyl)rifamycin SV
3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV
3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV
3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin
46713_FLUKA
46713_RIEDEL
62534-43-4
8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
8-(4-Methylpiperazinyliminomethyl) rifamycin SV
8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin
8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv
8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv
83907_FLUKA
83907_SIGMA
8CI)
AZT + Rifampin
Abrifam
Archidyn
Arficin
Arzide
BA-41166E
BIDD:PXR0014
BPBio1_000561
BSPBio_000509
Ba 41166
Ba 41166/E
Benemicin
Benemycin
Bio-0621
C06688
C43H58N4O12
CAS-13292-46-1
CCRIS 551
CHEBI:28077
CHEBI:455936
CHEMBL180
CID5381226
CID5388984
CID5458213
CID5702112
CID6604339
CID6708473
CID6842115
CID6912767
CID6913622
CPD001906767
D00211
DB01045
DRG-0109
Dione 21-acetate
Dipicin
DivK1c_000550
Doloresum
EINECS 236-312-0
Eremfat
Famcin
Fenampicin
HMS1569J11
HMS1920P08
HMS2089F12
HMS2092G09
HMS501L12
HSDB 3181
KBio1_000550
KBio2_000919
KBio2_003487
KBio2_006055
KBio3_003018
KBioGR_001780
KBioSS_000919
L-5103
L-5103 Lepetit
LS-7689
MLS000028552
MLS001148237
MLS001333745
MolPort-000-767-051
MolPort-002-513-586
MolPort-003-666-281
MolPort-006-395-891
NCGC00016699-01
NCGC00017365-01
NCGC00018178-01
NCGC00022678-03
NCGC00022678-04
NCGC00022678-05
NCGC00160500-01
 
NCI60_000309
NINDS_000550
NSC 113926
NSC-113926
NSC113926
Piperine & Rifampicin
Prestwick0_000525
Prestwick1_000525
Prestwick2_000525
Prestwick3_000525
Prestwick_833
R-Cin
R/AMP
R0079
R3501_SIAL
R3501_SIGMA
R5777_SIGMA
R7382_SIGMA
RAMP
RFP
RMP
Ramp
Reserpine & Rifampicin
Rf
Rfamipicin
Rifa
Rifadin
Rifadin (TN)
Rifadin I.V
Rifadin I.V.
Rifadin IV
Rifadin Iv
Rifadin, Rimactane, Rifampicin, Rifampin
Rifadine
Rifagen
Rifaldazin
Rifaldazine
Rifaldin
Rifam
Rifamicin AMP
Rifamor
Rifampicin
Rifampicin & EEP
Rifampicin & Propolis
Rifampicin (JP15/INN)
Rifampicin SV
Rifampicin [INN:BAN:JAN]
Rifampicin sodium
Rifampicina
Rifampicina [INN-Spanish]
Rifampicine
Rifampicine [French]
Rifampicinum
Rifampicinum [INN-Latin]
Rifampin
Rifampin (USP)
Rifampin [USAN]
Rifamsolin
Rifamycin
Rifamycin AMP
Rifamycin Amp
Rifaprodin
Rifcin
Rifinah
Rifobac
Rifoldin
Rifoldine
Riforal
Rimactan
Rimactane
Rimactane (TN)
Rimactazid
Rimactin
Rimactizid
Rimazid
Rimycin
Rofact
S1764_Selleck
SAM002264646
SMR000058322
SMR000653525
SPBio_002430
SPECTRUM1500529
STK080143
Sinerdol
Spectrum3_001837
Spectrum4_001250
Spectrum5_002018
Spectrum_000439
TNP00313
Tubocin
UNII-VJT6J7R4TR
WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1
nchembio884-comp4
rifampin
5
Folic Acidapproved, nutraceuticalPhase 4292459-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
6Hypolipidemic AgentsPhase 4, Phase 12228
7Antitubercular AgentsPhase 4, Phase 11061
8Anti-Infective AgentsPhase 4, Phase 2, Phase 3, Phase 1, Phase 017220
9Antibiotics, AntitubercularPhase 4, Phase 15971
10Anti-Bacterial AgentsPhase 4, Phase 3, Phase 2, Phase 1, Phase 09140
11VitaminsPhase 43857
12Nucleic Acid Synthesis InhibitorsPhase 4, Phase 13836
13Vitamin B ComplexPhase 42847
14AntimetabolitesPhase 4, Phase 19454
15Antiparasitic AgentsPhase 4, Phase 01854
16AntimalarialsPhase 41058
17Anti-Inflammatory AgentsPhase 4, Phase 2, Phase 38478
18Antiprotozoal AgentsPhase 4, Phase 01730
19Folic Acid AntagonistsPhase 41643
20Folinic AcidNutraceuticalPhase 42604
21FolateNutraceuticalPhase 42924
22Vitamin B9NutraceuticalPhase 42924
23
Leuprolideapproved, investigationalPhase 327953714-56-03911, 657181
Synonyms:
(D-Leu(6),des-gly-NH2(10),pro-ethylamide(9))-gonadotropin-releasing hormone
5-oxoPro-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-ProNHC2H5 dihydrate
5-oxoprolylhistidyltryptophylseryltyrosylleucylleucyl-n5-(diaminomethylidene)ornithyl-n-ethylprolinamide
AC1L1GZK
AC1L9B44
AC1Q5OPO
AR-1G9354
C07612
CID3911
CID441410
D00989
D08113
Eligard
Enantone
Enantone (TN)
I04-0109
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide
L001094
 
L002030
Leuprolide
Leuprolide Acetate
Leuprolide acetate
Leuprolide acetate (USAN)
Leuprorelin
Leuprorelin (INN)
Leuprorelin acetate (JAN)
Leuprorelina
Leuproreline
Leuprorelinum
Lupron
Lupron (TN)
N-[1-[[1-[[1-[[1-[[1-[[1-[[5-(diaminomethylideneamino)-1-[2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
NSC377526
NSC746847
PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-NHC2H5
PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-nhet
acetic acid
leuprolide
24
GoserelinapprovedPhase 321965807-02-547725, 5311128
Synonyms:
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
AC1NSK1T
CID5311128
Goserelin
Goserelin acetate
 
HMS2089D16
HS-2015
ICI-118630
MolPort-006-823-831
ZD-9393
Zoladex
goserelin
25
Miconazoleapproved, investigationalPhase 2, Phase 3302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
26
PrednisoloneapprovedPhase 2, Phase 3108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
27
MethylprednisoloneapprovedPhase 2, Phase 3108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
28
StreptomycinapprovedPhase 2, Phase 3, Phase 11857-92-119649
Synonyms:
12672-24-1
2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2S,3S,4S,5R)-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
2-[(1S,2S,3R,4S,5S,6R)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
2-[(1S,4S)-5-(diaminomethylideneamino)-2-[(2R,5S)-3-[(2S,5R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-3,4,6-trihydroxycyclohexyl]guanidine
3810-74-0
3810-74-0 (sulfate (2:3) salt)
4-18-00-07540 (Beilstein Handbook Reference)
47814-83-5
47816-81-9
57-92-1
82958-69-8
AC1L1LKU
AC1L2EK8
AC1O52TO
AC1O7EO6
AC1Q29OE
ACon1_001297
Agrept
Agrimycin
BPBio1_000355
BRN 0074498
BSPBio_000321
Bio-0644
C00413
C21H39N7O12
CCRIS 5730
CHEBI:17076
CHEBI:405369
CHEMBL1201194
CHEMBL173
CID19649
CID5999
CID6426892
CID6602485
Caswell No. 804
D08531
DB01082
EINECS 200-355-3
EPA Pesticide Chemical Code 006306
Estreptomicina [INN-Spanish]
Gerox
HMS2090P05
HSDB 1768
Hokko-mycin
Kantrex
 
LS-147053
LS-187084
Liposomal Streptomycin
MolPort-002-525-998
N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
NCGC00159339-02
NCGC00179603-01
NCGC00179603-02
NSC 14083
NSC14083
Neodiestreptopab
O-2-Deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-.alpha.-L-lyxofuranosyl-(1->4)-N,N'-bis(aminoiminomethyl)-D-streptamine and Liposome
Prestwick0_000321
Prestwick1_000321
Prestwick2_000321
Prestwick3_000321
SM
SPBio_002242
SRY
STREPTOMYCIN
STREPTOMYCIN SULFATE (2:3) SALT
Strepcen
Streptomicina
Streptomicina [Italian]
Streptomycin
Streptomycin & EEP
Streptomycin & Propolis
Streptomycin (INN)
Streptomycin (TN)
Streptomycin A
Streptomycin A sulfate
Streptomycin Sesquisulfate Hydrate
Streptomycin Sesquisulphate Hydrate
Streptomycin Sulfate
Streptomycin Sulphate
Streptomycin [INN:BAN]
Streptomycin a Sulfate
Streptomycin sulfate
Streptomycin sulphate
Streptomycin, Sulfate Salt
Streptomycine
Streptomycinum
Streptomyzin
Streptomyzin [German]
UNII-Y45QSO73OB
[2-Deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{n',n'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
[2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
streptomycin
29
MiltefosineapprovedPhase 33358066-85-63600
Synonyms:
1-Hexadecylphosphorylcholine
2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide, inner salt
3,5-Dioxa-4-phosphaunacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide
4-04-00-01460 (Beilstein Handbook Reference)
58066-85-6
AC1L1GAH
BRN 3690495
Baxter Oncology brand of miltefosine
Baxter brand of miltefosine
C039128
C15H32.C7H17NO4P
CHEBI:125047
CHEMBL125
CID3599
Choline hydroxide, hexadecyl hydrogen phosphate, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt
Choline phosphate, hexadecyl ester, hydroxide, inner salt (6CI)
Choline, hexadecyl hydrogen phosphate, inner salt
D 18506
D-18506
D02494
D18506
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, inner salt
Ethanaminium, 2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethyl-, hydroxide, innner salt
H-1850
HDPC
HMS1922D16
HMS2089J15
HePC
Hexadecyl 2-(trimethyl-.lambda.~5~-azanyl)ethyl hydrogen phosphate
 
Hexadecylphosphocholine
Hexadecylphosphorylcholine
I14-7244
IN1227
Impavido
LS-65132
M-7200
Miltefosin
Miltefosin C
Miltefosina
Miltefosina [INN-Spanish]
Miltefosine
Miltefosine (INN)
Miltefosine [INN:BAN]
Miltefosinum
Miltefosinum [INN-Latin]
Miltex
Miltéfosine
MolPort-003-665-519
Monohexadecylphosphocholine
Monohexadecylphosphorylcholine
NCGC00095169-01
NCGC00095169-02
NCGC00095169-03
NSC605583
Prasfarma brand of miltefosine
SPECTRUM1505329
ST51055612
TF-002
UNII-53EY29W7EC
hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
n-Hexadecylphosphorylcholine
30
Minocyclineapproved, investigationalPhase 317310118-90-85281021
Synonyms:
(2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE
(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10118-90-8
13614-98-7 (mono-hydrochloride)
4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
4708-96-7
7-Dimethylamino-6-demethyl-6-deoxytetracycline
AC1NQXWM
Arestin
BRN 3077644
Bio-0062
Borymycin
C07225
C23H27N3O7
CHEBI:50694
CHEBI:529981
CHEMBL1434
CHEMBL259172
CID5281021
CL 59806
CRL-1605 & Minocycline
D05045
Dynacin
HMS2090D03
HSDB 3130
LMPK07000002
 
LS-93850
Lactoferrin B & Minocycline
Lactoferrin H & Minocycline
MINO
MIY
Minociclina
Minociclina [INN-Spanish]
Minociclinum
Minocin
Minocin (Hydrochloride)
Minocline
Minocyclin
Minocycline
Minocycline (USAN/INN)
Minocycline Hydrochloride
Minocycline Monohydrochloride
Minocycline [USAN:BAN:INN]
Minocyclinum
Minocyclinum [INN-Latin]
NCGC00178854-01
NSC 141993
NSC141993
Solodyn
UNII-FYY3R43WGO
Vectrin (Hydrochloride)
Ximino
minociclinum
minocycline
nchembio.559-comp1
31
ClarithromycinapprovedPhase 2, Phase 324681103-11-984029
Synonyms:
(14R)-14-Hydroxyclarithromycin
116836-41-0
6-O-Methylerythromycin
6-O-Methylerythromycin a
6-O-methyl erythromycin
81103-11-9
A-56268
AC-6813
AC1L1HJO
AC1L36NJ
AC1NFSZE
AC1NR4MY
AC1NSJWH
AC1O52DV
AC1Q6O1T
ANX-015
Abbotic
Abbott-56268
Adel
Astromen
BB_NC-1450
BIDD:GT0200
BSPBio_003453
Biaxin
Biaxin (TN)
Biaxin HP
Biaxin XL
Biaxin filmtab
Biaxin xl filmtab
Bicrolid
Bio-0020
C06912
C2220
C30H54O11.C9H19NO2
CCRIS 8833
CHEBI:136451
CHEBI:3732
CHEMBL143
CHEMBL1741
CID10147055
CID10328822
CID11814635
CID11828745
CID11969952
CID4663848
CID489010
CID5284534
CID5311050
CID54688
CID6426662
CID84029
CID9810688
CID9811194
CLA
CLARITHROMYCIN
CLM & IL-12
CPD000466382
CRL-1605 & Clarithromycin
CTY
Clacine
Clambiotic
Claribid
Claricide
Clarith
Clarithromycin
Clarithromycin & Interleukin-12
Clarithromycin (JP15/USP/INN)
Clarithromycin [USAN:INN:BAN:JAN]
Clarithromycin extended release
Clarithromycin suspension or tablets
Clarithromycina
Clarithromycine
Clarithromycine [INN-French]
 
Clarithromycinum
Clarithromycinum [INN-Latin]
Claritromicina
Claritromicina [INN-Spanish]
Clathromycin
Cyllid
Cyllind
D00276
DRG-0099
DivK1c_006655
HMS1922H09
HMS2051G18
HMS2090O11
HMS2094M05
Helas
Heliclar
I05-0074
KBio1_001599
KBio2_000509
KBio2_003077
KBio2_005645
KBio3_002673
KBioGR_001218
KBioSS_000509
Klacid
Klaciped
Klaricid
Klaricid H.P
Klaricid H.P.
Klaricid Pediatric
Klaricid XL
Klarid
Klarin
Klax
Kofron
LMPK04000014
LS-1812
Lactoferrin B & Clarithromycin
Lactoferrin H & Clarithromycin
MLS000759516
MLS001201751
MLS001424066
Mabicrol
Macladin
Maclar
Mavid
MolPort-002-507-425
MolPort-003-845-969
MolPort-005-910-192
MolPort-005-934-146
NCGC00178054-01
NSC643733
Naxy
O(6)-methylerythromycin
SAM001246748
SDP-015
SMR000466382
SPBio_001855
SPECTRUM1504231
STK801952
SpecPlus_000559
Spectrum2_001668
Spectrum3_001667
Spectrum4_000629
Spectrum5_001729
Spectrum_000089
TE-031
TE031
UNII-H1250JIK0A
Veclam
Zeclar
clarithromycin
clarithromycina
hydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexame
32
ClindamycinapprovedPhase 315718323-44-929029
Synonyms:
13441-63-9
16669-21-9
18323-44-9
21462-39-5 (mono-hydrochloride)
24620-78-8
24696-19-3
58207-19-5
7(S)-Chloro-7-deoxylincomycin
7-CDL
7-Chloro-7-deoxylincomycin
7-Chlorolincomycin
7-Deoxy-7(S)-chlorolincomycin
AC1L1EGQ
AC1L1GLA
AC1L9JV8
AC1MHD7N
AC1MHE1M
AC1MHUOE
AC1MHX4G
AC1NWAKO
AC1O7ENS
AC1O7GED
AC1OFCIP
AC1OFCIV
AC1OFCJ1
AC1OFCJ7
AC1OIBYJ
AC1OIBYL
AC1OIBYN
AC1Q2V4O
Antirobe
BIDD:GT0418
BPBio1_000236
BRD-A23034328-003-03-4
BSPBio_000214
BSPBio_002049
C06914
C18H33ClN2O5S
CAS-21462-39-5
CHEBI:3745
CHEMBL187
CID2786
CID29029
CID3000512
CID3001928
CID3032758
CID3034218
CID446598
CID5702026
CID6602476
CID6604361
CID7048642
CID7048644
CID7048646
CID7048648
CID7276014
CID7276016
CID7276018
CID9812677
CLDM
CLINDA & IL-12
CLY
Chlolincocin
Chlorlincocin
Chlorodeoxylincomycin
Chlorolincomycin
Cleocin
Cleocin (TN)
Cleocin (tn)
Cleocin HCl
Cleocin Hydrochloride
Cleocin T Gel
Cleocin T Lotion
Cleocin T Topical Solution
 
Clinda-derm
ClindaDerm
Clindagel
Clindamax
Clindamicina
Clindamicina [INN-Spanish]
Clindamycin
Clindamycin & Interleukin 12
Clindamycin & VRC3375
Clindamycin (USAN/INN)
Clindamycin Phosphate
Clindamycin [USAN:BAN:INN]
Clindamycine
Clindamycine [French]
Clindamycine [INN-French]
Clindamycinum
Clindamycinum [INN-Latin]
Clindesse
Clinimycin
D00277
DB01190
Dalacin C
Dalacin C Flavored Granules
Dalacin C Phosphate
Dalacin T Topical Solution
Dalacine
DivK1c_000464
EINECS 242-209-1
Evoclin
HMS2089A05
HMS2089N16
HSDB 3037
I06-0826
IDI1_000464
KBio1_000464
KBio2_000638
KBio2_003206
KBio2_005774
KBio3_001269
KBioGR_000844
KBioSS_000638
Klimicin
Klindan 300
LS-187128
LS-98131
MLS001183714
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside
MolPort-002-323-206
MolPort-002-964-479
NCGC00016752-01
NCGC00178843-01
NCGC00179636-01
NINDS_000464
Prestwick0_000137
Prestwick1_000137
Prestwick2_000137
Prestwick3_000137
ResiDerm A
SMP2_000295
SMR000677917
SPBio_000670
SPBio_002153
STK177246
STOCK1N-31150
Sobelin
Spectrum2_000885
Spectrum3_000355
Spectrum4_000292
Spectrum5_001525
Spectrum_000158
U 21251
U-21,251
U-21251
UNII-3U02EL437C
Zindaclin
clindamycin
33Adjuvants, ImmunologicPhase 31783
34Prednisolone phosphatePhase 2, Phase 31082
35Prednisolone hemisuccinatePhase 2, Phase 31082
36VaccinesPhase 3, Phase 2, Phase 16085
37Protective AgentsPhase 2, Phase 35651
38Aluminum sulfatePhase 2, Phase 379
39Contraceptives, OralPhase 3, Phase 13734
40Angiogenesis Modulating AgentsPhase 3, Phase 23611
41Angiogenesis InhibitorsPhase 3, Phase 23688
42AndrogensPhase 31162
43meglumine antimoniatePhase 3, Phase 025
44Hormone AntagonistsPhase 2, Phase 310002
45Dermatologic AgentsPhase 2, Phase 34555
46Gastrointestinal AgentsPhase 2, Phase 3, Phase 16401
47glucocorticoidsPhase 2, Phase 33896
48CyclosporinsPhase 2, Phase 3873
49Calcineurin InhibitorsPhase 2, Phase 31223
50Antifungal AgentsPhase 2, Phase 33015

Interventional clinical trials:

(show all 43)
idNameStatusNCT IDPhase
1Effect of Additional Clofazimine on Erythema Nodosum Leprosum (ENL) Reactions in LeprosyCompletedNCT01290744Phase 4
2Effect of Weight and/or Obesity on Dapsone Drug ConcentrationsCompletedNCT01165840Phase 4
3Feasibility and Effectiveness of Community Based Isoniazid Preventive Therapy in KenyaCompletedNCT00850915Phase 4
4Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity SyndromeRecruitingNCT02550080Phase 4
5Uniform Multidrug Therapy Regimen for Leprosy PatientsActive, not recruitingNCT00669643Phase 4
6Ciclosporin in the Management of New Type 1 Reactions in LeprosyCompletedNCT00919815Phase 2, Phase 3
7Efficacy and Safety Study of Immunomodulator as an Adjunct Therapy in Pulmonary Tuberculosis (TB) Retreatment PatientsCompletedNCT00265226Phase 3
8Efficacy and Safety of Immunomodulator as an Adjunct Therapy in New Pulmonary Tuberculosis(Category I) Patients.CompletedNCT00341328Phase 3
9Safety/Efficacy Trial of Killed Leishmania Vaccine in Volunteers With no Response to LeishmaninCompletedNCT00429715Phase 2, Phase 3
10Safety/Efficacy Trial of Killed Leishmania Vaccine in Volunteers With Positive Response to Leishmanin (LST>0)CompletedNCT00429780Phase 2, Phase 3
11Thalidomide for the Treatment of Hormone-Dependent Prostate CancerCompletedNCT00004635Phase 3
12Efficacy Trial on Oral Miltefosine in Comparison With Glucantime in the Treatment of ACL Caused by L. TropicaCompletedNCT00351520Phase 3
13WHO Drug Study for Buruli Ulcer - Comparison of SR8 and CR8RecruitingNCT01659437Phase 2, Phase 3
14To Compare the Efficacy and Safety of Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel of CHL Versus DUAC® GelRecruitingNCT02005666Phase 3
15Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot StudyActive, not recruitingNCT00203697Phase 3
16Leprosy Skin Test Antigens TrialCompletedNCT00128193Phase 2
17Ciclosporin in the Management of Steroid Resistant Type 1 Reactions in LeprosyCompletedNCT00919451Phase 2
18Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum LeprosumCompletedNCT00919776Phase 2
19Ciclosporin in the Management of New Erythema Nodosum LeprosumCompletedNCT00919542Phase 2
20Phase II Trial of Peginterferon Alpha-2b and Thalidomide in Adults With Recurrent GliomasCompletedNCT00047879Phase 2
21Progression of HIV-Disease Under Low Dose CorticosteroidsCompletedNCT01299948Phase 2
22Virgin Coconut Oil Oral Supplementation for Leprosy PatientsActive, not recruitingNCT01885611Phase 1, Phase 2
23Prevention of Disability: Proposal for a Guidance Manual for Leprosy PatientsCompletedNCT01006759Phase 1
24Leprosy Skin Test Antigens Phase 1CompletedNCT01920750Phase 1
25Study of the Safety and Immunogenicity of Bacille Calmette Guerin (BCG) VaccineCompletedNCT00654316Phase 1
26Measurement of Anti-TB Drugs in Lung Tissue From Patients Having Surgery to Treat TuberculosisCompletedNCT00816426Phase 1
27Microcirculatory Impairment in Patients With LeprosyCompletedNCT02085317
28Molecular and Immunological Tools for Detection of Strain Diversity, Drug Resistance and Immunological ResponsesCompletedNCT00138437
29Molecular Epidemiology of Leprosy - PhilippinesCompletedNCT00315809
30The Use of Low Level Laser Therapy for Wound Healing in Leprosy PatientsCompletedNCT00860717
31Impact of the Virtual Human Project on Team-based Learning: A Randomized-controlled TrialCompletedNCT02484469
32SMF to Improve Performance of Microscopy for the Diagnosis of PTB in a High HIV Prevalence SettingCompletedNCT02701439
33γ-irradiated BCG to Train Innate ImmunityCompletedNCT02259608
34Granuloma Annulare Treated With Rifampin, Ofloxacin, and Minocycline Combination TherapyCompletedNCT00720980
35Efficacy of Topical Liposomal Form of Drugs in Cutaneous LeishmaniasisCompletedNCT01050777Phase 0
36Genetics of Hepatitis C Virus InfectionCompletedNCT00005657
37Toll-like Receptor 2 Gene Polymorphism, Serum Cytokines and Susceptibility to Disease Severity or Treatment Response of Pulmonary TuberculosisCompletedNCT00772408
38Extramembranous and Interosseous Technique of Tibialis Posterior Tendon TransferRecruitingNCT01751503
39Platelet Rich Plasma and Hydrodissection for Carpal Tunnel SyndromeRecruitingNCT02696161
40Montelukast in ENL ReactionNot yet recruitingNCT00406861
41Treatment Protocol for Clofazamine in the Long Term Treatment of LeprosyNo longer availableNCT00852345
42Safety and Efficacy of Different Onset Times of Treatment With Pulsed Dye Laser on Improvement of Surgical ScarsTerminatedNCT00506363
43Safety and Efficacy of Different Intervals of Pulsed Dye Laser Sessions on Improvement of Surgical ScarsWithdrawnNCT00506090

Search NIH Clinical Center for Leprosy

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: leprosy

Genetic Tests for Leprosy

About this section

Anatomical Context for Leprosy

About this section

MalaCards organs/tissues related to Leprosy:

33
Skin, Eye, T cells, Testes, Liver, Breast, Lung

FMA organs/tissues related to Leprosy:

16
Superficial peripheral nerves, Skin, Mucous membranes of the upper respiratory tract, Anterior chamber of the eyes, Testes

Animal Models for Leprosy or affiliated genes

About this section

MGI Mouse Phenotypes related to Leprosy:

38 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.5IFNG, IL10, IL12RB2, IL2, SLC11A1, TLR2
2MP:00053709.3IFNG, IL10, IL12RB2, IL2, IL4, LTA
3MP:00053889.2IFNG, IL10, IL2, IL4, LTA, PARK2
4MP:00053799.1CD40LG, IFNG, IL10, IL12RB2, IL2, IL4
5MP:00053818.9IFNG, IL10, IL12RB2, IL2, IL4, NOD2
6MP:00053858.9CD40LG, IFNG, IL10, IL12RB2, IL2, LTA
7MP:00053908.2CCDC122, CD40LG, IFNG, IL10, IL4, LTA
8MP:00053767.9CCDC122, CD40LG, IFNG, IL10, IL12RB2, IL2
9MP:00107687.9CD40LG, IFNG, IL10, IL2, IL4, LTA
10MP:00053877.7CD40LG, IFNG, IL10, IL12RB2, IL18RAP, IL2
11MP:00053977.6CD40LG, IFNG, IL10, IL12RB2, IL18RAP, IL2

Publications for Leprosy

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Articles related to Leprosy:

(show top 50)    (show all 1798)
idTitleAuthorsYear
1
Integrative literature review of the reported uses of serological tests in leprosy management. (27192583)
2016
2
Psychiatric Morbidity among Subjects with Leprosy and Albinism in South East Nigeria: A Comparative Study. (26097762)
2015
3
Indigenous Cases of Leprosy (Hansen's Disease) in Southern Mississippi. (26434167)
2015
4
Borderline lepromatous leprosy with type 1 (downgrading) reaction. (24252148)
2013
5
Interleukin-17F single-nucleotide polymorphism (7488T>C) and its association with susceptibility to leprosy. (24164796)
2013
6
Role of HLA, KIR, MICA, and cytokines genes in leprosy. (23936864)
2013
7
History of infectious diseases development in the Old and the Middle Ages with the emphasis on the plague and leprosy. (23984623)
2013
8
Intolerance to leprosy multi-drug therapy: more common in women? (24428115)
2013
9
Genetic evidence of TAP1 gene variant as a susceptibility factor in Indian leprosy patients. (23395648)
2013
10
The effect of systemic corticosteroid therapy on the expression of toll-like receptor 2 and toll-like receptor 4 in the cutaneous lesions of leprosy Type 1 reactions. (22348338)
2012
11
Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy. (23283458)
2012
12
Comparing the clinical and histological diagnosis of leprosy and leprosy reactions in the INFIR cohort of Indian patients with multibacillary leprosy. (22745841)
2012
13
Leprosy among migrant workers: ensuring proper treatment. (23614250)
2012
14
Histopathological examination of nerve samples from pure neural leprosy patients: obtaining maximum information to improve diagnostic efficiency. (22415265)
2012
15
Hansen's disease (Leprosy): current and future pharmacotherapy and treatment of disease-related immunologic reactions. (22392826)
2012
16
Characterization of the profession/occupation of individuals affected by leprosy and the relationship with limitations in professional activities. (23077777)
2012
17
Chronic rhinitis: a manifestation of leprosy. (21938685)
2011
18
Cytokine and protein markers of leprosy reactions in skin and nerves: baseline results for the North Indian INFIR cohort. (22180790)
2011
19
Leprosy elimination campaign in Qazvin province, Islamic Republic of Iran (2006-07). (22355944)
2011
20
Study of cytokine response against panel of purified Mycobacterium leprae antigens by using whole blood assay in subjects residing in a resettlement village of cured leprosy patients. (21229844)
2010
21
SNP 668C (-44) alters a NF-kappaB1 putative binding site in non-coding strand of human beta-defensin 1 (DEFB1) and is associated with lepromatous leprosy. (19460328)
2009
22
Functional haplotypes that produce normal ficolin-2 levels protect against clinical leprosy. (19434912)
2009
23
A case of recurrent rash and leg numbness mimicking systemic rheumatic disease: the occurrence of leprosy in a nonendemic area. (17551381)
2007
24
Tuberculoid leprosy confined to glans penis in two cases. (15282972)
2004
25
Linkage of leprosy susceptibility to Parkinson's disease genes. (15301585)
2004
26
Lepromatous leprosy with extensive unusual ulcerations and cachexia. Is it the first case of Lucio's phenomenon from Iran? (15217312)
2004
27
Molluscum contagiosum-like lesions in lepromatous leprosy. (15267197)
2003
28
Localized linear lesions in lepromatous leprosy. (11898466)
2001
29
Association and linkage of leprosy phenotypes with HLA class II and tumour necrosis factor genes. (11477474)
2001
30
Lagophthalmos in leprosy. (9598404)
1998
31
The current situation of lagophthalmos and keratopathy of leprosy in PR China. (9598407)
1998
32
Charles Bonnet syndrome in leprosy; prevalence and clinical characteristics. (8712028)
1996
33
Host parasite response in nerve in leprosy. (8727123)
1996
34
Localized borderline lepromatous leprosy. (8537706)
1995
35
Reply: 'Results of surgical procedures for the correction of foot-drop and lagophthalmus due to leprosy'. (7861931)
1994
36
Comment: 'Results of surgical procedures for the correction of foot-drop and of lagophthalmus due to leprosy'. (8231612)
1993
37
Tongue involvement in lepromatous leprosy. (8425797)
1993
38
Electrocardiographic alterations in lepromatous leprosy patients with concomitant Trypanosoma cruzi infection. (8228450)
1993
39
Lepromatous leprosy: nasal manifestations and treatment with minocycline. (1543336)
1992
40
Camptodactyly simulating claw hand in a patient with indeterminate leprosy. (1783793)
1991
41
In vitro effect of interleukin-2 on proliferative responses of peripheral blood T cells from leprosy patients. (1781183)
1991
42
Single lesion subpolar lepromatous leprosy and its possible mode of origin. (2659697)
1989
43
Evaluation of anti-cardiolipin antibody and its cross-reactivity in sera of patients with lepromatous leprosy. (3740940)
1986
44
Should indeterminate leprosy ever be diagnosed? (7195888)
1981
45
Mechanism of nerve destruction in tuberculoid-borderline leprosy. An electron-microscopic study. (4582968)
1973
46
The Kveim test in lepromatous and tuberculoid leprosy. (5394258)
1969
47
Pure neural tuberculoid leprosy. (4283894)
1965
48
49
50

Variations for Leprosy

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Clinvar genetic disease variations for Leprosy:

5
id Gene Variation Type Significance SNP ID Assembly Location
1TLR2NM_003264.4(TLR2): c.2029C> T (p.Arg677Trp)single nucleotide variantrisk factorrs121917864GRCh37Chr 4, 154626088: 154626088

Expression for genes affiliated with Leprosy

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Search GEO for disease gene expression data for Leprosy.

Pathways for genes affiliated with Leprosy

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Pathways related to Leprosy according to GeneCards Suite gene sharing:

(show all 47)
idSuper pathwaysScoreTop Affiliating Genes
110.0MRC1, TLR1, TLR2
29.9IFNG, TLR2, TNF
39.9IFNG, TLR2, TNF
4
Show member pathways
9.9IFNG, LTA, TNF
59.8IFNG, IL10, TNF
69.8IFNG, IL18RAP, IL2
79.8IFNG, IL2, TNF
8
Show member pathways
9.8IFNG, IL2, TNF
9
Show member pathways
9.8IL2, IL4, LTA
109.8IFNG, IL2, IL4
119.7IFNG, TLR1, TLR2, TNF
129.7IFNG, IL10, TLR2, TNF
13
Show member pathways
9.7IFNG, IL4, TLR1, TLR2
149.6IFNG, IL10, IL12RB2, IL2
15
Show member pathways
9.6IFNG, IL10, IL2, TNF
169.6IFNG, IL10, IL2, TNF
179.6CD40LG, IL10, IL4, LTA
189.6IFNG, IL2, IL4, TNF
19
Show member pathways
9.5CD40LG, LTA, TLR1, TLR2, TNF
20
Show member pathways
9.5CD40LG, LTA, TLR1, TLR2, TNF
219.5CD40LG, IFNG, IL2, IL4
22
Show member pathways
9.5IFNG, IL4, TLR1, TLR2, TNF
239.5CD40LG, IFNG, IL10, TLR2, TNF
24
Show member pathways
9.5IL18RAP, NOD2, TLR1, TLR2, TNF
25
Show member pathways
9.4IFNG, IL10, IL18RAP, IL2, TNF
26
Show member pathways
9.4IFNG, IL12RB2, IL18RAP, IL2, IL4
279.4IFNG, IL10, IL2, IL4, LTA
28
Show member pathways
9.4IFNG, IL10, IL12RB2, IL2, IL4
299.4IFNG, IL10, IL12RB2, IL2, IL4
309.3IFNG, IL10, IL2, IL4, TNF
319.3IFNG, IL10, IL2, IL4, TNF
32
Show member pathways
9.3CD40LG, IFNG, IL2, IL4, TNF
33
Show member pathways
9.3CD40LG, IL2, LTA, TLR1, TLR2, TNF
34
Show member pathways
9.3IFNG, IL10, IL2, TLR1, TLR2, TNF
35
Show member pathways
9.2IFNG, IL2, IL4, LTA, TLR2, TNF
369.2CD40LG, IL10, IL4, LTA, TLR2, TNF
37
Show member pathways
9.2CD40LG, IFNG, IL10, IL4, TLR2, TNF
38
Show member pathways
9.2IFNG, IL10, IL2, IL4, LTA, TNF
39
Show member pathways
9.1CD40LG, IFNG, IL10, IL2, IL4, TNF
409.0IFNG, IL10, MRC1, NOD2, TLR1, TLR2
419.0IFNG, IL10, IL12RB2, IL2, IL4, LTA
42
Show member pathways
9.0CD40LG, IL10, IL12RB2, IL2, IL4, LTA
43
Show member pathways
8.7IFNG, IL10, IL12RB2, IL18RAP, IL2, LTA
44
Show member pathways
8.6CD40LG, IL10, IL12RB2, IL2, IL4, LTA
45
Show member pathways
8.6CD40LG, IFNG, IL10, IL12RB2, IL18RAP, IL2
46
Show member pathways
8.1CD40LG, IFNG, IL10, IL12RB2, IL18RAP, IL2
47
Show member pathways
8.0CD40LG, IFNG, IL12RB2, IL18RAP, IL2, LTA

GO Terms for genes affiliated with Leprosy

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Biological processes related to Leprosy according to GeneCards Suite gene sharing:

(show all 46)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chemokine productionGO:003272210.8TLR2, TNF
2positive regulation of chronic inflammatory response to antigenic stimulusGO:000287610.8LTA, TNF
3positive regulation of interleukin-6 biosynthetic processGO:004541010.8IFNG, TLR1
4positive regulation of calcidiol 1-monooxygenase activityGO:006055910.8IFNG, TNF
5positive regulation of membrane protein ectodomain proteolysisGO:005104410.8IFNG, TNF
6receptor biosynthetic processGO:003280010.8IL10, TNF
7cytokine secretion involved in immune responseGO:000237410.8NOD2, TLR2
8negative regulation of cytokine secretion involved in immune responseGO:000274010.7IL10, TNF
9regulation of immunoglobulin secretionGO:005102310.7CD40LG, TNF
10positive regulation of mononuclear cell migrationGO:007167710.7IL4, TNF
11positive regulation of nitric-oxide synthase biosynthetic processGO:005177010.7NOD2, TLR2
12positive regulation of T cell differentiationGO:004558210.6IL2, IL4
13type 2 immune responseGO:004209210.6IL10, IL4
14regulation of reactive oxygen species metabolic processGO:200037710.6PARK2, TNF
15cellular response to triacyl bacterial lipopeptideGO:007172710.6TLR1, TLR2
16positive regulation of phagocytosisGO:005076610.6SLC11A1, TNF
17positive regulation of interleukin-1 beta secretionGO:005071810.6IFNG, NOD2
18defense response to Gram-positive bacteriumGO:005083010.5LTA, TLR2, TNF
19positive regulation of osteoclast differentiationGO:004567210.5IFNG, TNF
20negative regulation of nitric oxide biosynthetic processGO:004501910.5IL10, IL4
21positive regulation of chemokine biosynthetic processGO:004508010.5IFNG, IL4, TNF
22positive regulation of tumor necrosis factor productionGO:003276010.5IFNG, NOD2, TLR2
23negative regulation of growth of symbiont in hostGO:004413010.5IFNG, IL10, TNF
24defense response to protozoanGO:004283210.5IFNG, IL10, IL4
25protein import into nucleus, translocationGO:000006010.4IFNG, SLC11A1, TNF
26toll-like receptor 4 signaling pathwayGO:003414210.4NOD2, TLR1, TLR2
27B cell differentiationGO:003018310.4CD40LG, IL10, IL4
28positive regulation of T cell proliferationGO:004210210.4IFNG, IL2, IL4
29toll-like receptor signaling pathwayGO:000222410.3NOD2, TLR1, TLR2
30positive regulation of isotype switching to IgG isotypesGO:004830410.3IFNG, IL2, IL4
31positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.3IL10, IL4, TNF
32MyD88-dependent toll-like receptor signaling pathwayGO:000275510.3NOD2, TLR1, TLR2
33regulation of immune responseGO:005077610.3CD40LG, IFNG, IL4
34positive regulation of MHC class II biosynthetic processGO:004534810.3IFNG, IL10, IL4
35negative regulation of gene expressionGO:001062910.2IFNG, PARK2, TNF
36defense responseGO:000695210.2NOD2, TLR1, TNF
37positive regulation of protein phosphorylationGO:000193410.1IL2, IL4, TNF
38cell surface receptor signaling pathwayGO:000716610.1IFNG, IL12RB2, IL18RAP, TNF
39positive regulation of interferon-gamma productionGO:003272910.0IL12RB2, IL2, LTA, SLC11A1, TNF
40inflammatory responseGO:000695410.0IL10, SLC11A1, TLR1, TNF
41response to drugGO:00424939.9IFNG, IL10, IL4, LTA
42signal transductionGO:00071659.5IL18RAP, LTA, MRC1, PARK2, TLR1, TLR2
43response to lipopolysaccharideGO:00324969.5IL10, IL12RB2, LTA, SLC11A1
44defense response to bacteriumGO:00427429.4IFNG, IL10, NOD2, TLR1, TNF
45immune responseGO:00069559.0IFNG, IL10, IL18RAP, IL2, IL4, SLC11A1
46positive regulation of transcription from RNA polymerase II promoterGO:00459448.6IFNG, IL10, IL2, IL4, NOD2, PARK2

Sources for Leprosy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet