MCID: LPT007
MIFTS: 13

Leptomeningeal Amyloidosis malady

Genetic diseases (common) category

Summaries for Leptomeningeal Amyloidosis

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66Wikipedia, 34MalaCards
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Wikipedia:66 The meninges (/m??n?nd?i?z/,singular: meninx (/?mi?n??ks/ or /?m?n??ks/), from Ancient more...

MalaCards: Leptomeningeal Amyloidosis, also known as amyloidosis, leptomeningeal, is related to amyloidosis and siderosis. An important gene associated with Leptomeningeal Amyloidosis is TTR (transthyretin).

Aliases & Classifications for Leptomeningeal Amyloidosis

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21GeneTests, 46Novoseek
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Aliases & Descriptions:

leptomeningeal amyloidosis 21
amyloidosis, leptomeningeal 46


Related Diseases for Leptomeningeal Amyloidosis

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18GeneCards, 19GeneDecks
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Diseases related to Leptomeningeal Amyloidosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1amyloidosis10.6
2siderosis10.1
3polyneuropathy10.1
4superficial siderosis10.1

Symptoms for Leptomeningeal Amyloidosis

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Drugs & Therapeutics for Leptomeningeal Amyloidosis

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Leptomeningeal Amyloidosis

Search NIH Clinical Center for Leptomeningeal Amyloidosis

Search CenterWatch for Leptomeningeal Amyloidosis

Genetic Tests for Leptomeningeal Amyloidosis

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21GeneTests
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Genetic tests related to Leptomeningeal Amyloidosis:

id Genetic test Affiliating Genes
1 Leptomeningeal Amyloidosis21

Anatomical Context for Leptomeningeal Amyloidosis

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Animal Models for Leptomeningeal Amyloidosis or affiliated genes

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Publications for Leptomeningeal Amyloidosis

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53PubMed
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Articles related to Leptomeningeal Amyloidosis:

idTitleAuthorsYear
1
Leptomeningeal amyloidosis due to A25T TTR mutation: a case report. (23465688)
2013
2
A new transthyretin mutation associated with leptomeningeal amyloidosis. (21838472)
2011
3
Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in cerebrospinal fluid. (22091638)
2011
4
A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis. (18579156)
2008
5
A case of biopsy-proven leptomeningeal amyloidosis and intravenous Ig-responsive polyneuropathy associated with the Ala25Thr transthyretin gene mutation. (16690499)
2006
6
Biochemical characteristics of variant transthyretins causing hereditary leptomeningeal amyloidosis. (16399646)
2005
7
Familial leptomeningeal amyloidosis with a transthyretin variant Asp18Gly representing repeated subarachnoid haemorrhages with superficial siderosis. (15377697)
2004
8
Transthyretin Leu12Pro is associated with systemic, neuropathic and leptomeningeal amyloidosis. (10071047)
1999
9
Massive leptomeningeal amyloidosis associated with a Val30Met transthyretin gene. (8857732)
1996

Variations for Leptomeningeal Amyloidosis

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Expression for genes affiliated with Leptomeningeal Amyloidosis

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Leptomeningeal Amyloidosis

Search GEO for disease gene expression data for Leptomeningeal Amyloidosis.

Pathways for genes affiliated with Leptomeningeal Amyloidosis

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Compounds for genes affiliated with Leptomeningeal Amyloidosis

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GO Terms for genes affiliated with Leptomeningeal Amyloidosis

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Products for genes affiliated with Leptomeningeal Amyloidosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Leptomeningeal Amyloidosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet