MCID: LPT001
MIFTS: 68

Leptospirosis malady

Categories: Rare diseases, Infectious diseases, Skin diseases

Aliases & Classifications for Leptospirosis

About this section
Sources:
10Disease Ontology, 45NIH Rare Diseases, 47Novoseek, 12DISEASES, 51Orphanet, 36MeSH, 2CDC, 65UMLS, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 37MESH via Orphanet, 66UMLS via Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Leptospirosis:

Name: Leptospirosis 10 45 47 12 51 36 2 65
Hemorrhagic Jaundice 45 65
Fort Bragg Fever 10 65
Canicola Fever 45 65
Weil Disease 45 65
Leptospiral or Spirochetal Jaundice 10
Leptospirosis Icterohaemorrhagica 10
Leptospirosis Icterohemorrhagica 10
Equine Infectious Anemia 65
Icterohemorrhagic Fever 45
Rat Catcher's Yellows 10
 
Canine Leptospirosis 65
Spirochetal Jaundice 10
Swineherd's Disease 45
Cane-Cutter Fever 45
Stuttgart Disease 45
Rice-Field Fever 45
Nanukayami Fever 10
Weil's Disease 10
Swamp Fever 45
Nanukayami 65
Mud Fever 45

Characteristics:

Orphanet epidemiological data:

51
leptospirosis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe); Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology10 DOID:2297
ICD1027 A27, A27.0, A27.9
ICD9CM29 100, 100.0, 100.9
NCIt42 C84825
Orphanet51 509
MESH via Orphanet37 D007922
UMLS via Orphanet66 C0023364
ICD10 via Orphanet28 A27.0, A27.8, A27.9
UMLS65 C0023364, C0043102, C1306220 C0686708, C0554636, C1398232, C0241954, C0014661, more

Summaries for Leptospirosis

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Disease Ontology:10 A primary bacterial infectious disease that involves systemic infection, has material basis in Leptospira, which is transmitted by contact with water, food, or soil containing urine from the infected animals. The infection has symptom jaundice, has symptom chills, has symptom fever, has symptom muscle pain, and has symptom hepatomegaly.

MalaCards based summary: Leptospirosis, also known as hemorrhagic jaundice, is related to splenic infarction and meningitis, and has symptoms including jaundice, chills and fever. An important gene associated with Leptospirosis is CD40LG (CD40 Ligand), and among its related pathways are NF-kappa B signaling pathway and Innate Lymphoid Cell Differentiation Pathways. Affiliated tissues include lung, kidney and heart, and related mouse phenotypes are renal/urinary system and digestive/alimentary.

CDC:2 Leptospirosis is a bacterial disease that affects humans and animals. It is caused by bacteria of the genus Leptospira. In humans, it can cause a wide range of symptoms, some of which may be mistaken for other diseases. Some infected persons, however, may have no symptoms at all.

Wikipedia:68 Leptospirosis is an infection caused by corkscrew-shaped bacteria called Leptospira. Signs and symptoms... more...

Related Diseases for Leptospirosis

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Diseases related to Leptospirosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 370)
idRelated DiseaseScoreTop Affiliating Genes
1splenic infarction29.5CD40LG, CRP, F2
2meningitis29.3CRP, IL10, IL1B, TLR2, TNF
3malaria26.0CCL2, CD40LG, CRP, HLA-DRB1, IL10, IL1B
4congenital cataract-progressive muscular hypotonia-hearing loss-developmental delay syndrome10.8HLA-DRB1, TNF
5microsomia hemifacial radial defects10.8HLA-DRB1, TNF
6punctate palmoplantar keratoderma type 210.7IL10, TNF
7autoimmune polyglandular syndrome type 210.7HLA-DRB1, TNF
8best1 retinopathy10.7HLA-DRB1, TNF
9primary progressive freezing gait10.7IL10, TNF
10non-distal monosomy 10q10.7HLA-DRB1, TNF
11kearns-sayre syndrome10.7IL10, TNF
12multifocal lymphangioendotheliomatosis with thrombocytopenia10.7IL10, TNF
13androgen insensitivity syndrome, mild10.7HLA-DRB1, TNF
14alternating exotropia10.6IL10, TNF
15achalasia10.6IL10, TNF
16maculopapular lupus rash10.6HLA-DRB1, IL10
17polycythemia10.6IL1B, TNF
18hair defect with photosensitivity and mental retardation10.6TLR2, TNF
19noonan-like/multiple giant cell lesion syndrome10.6HLA-DRB1, TLR2, TNF
20rhizomelic dysplasia patterson lowry type10.5HLA-DRB1, TNF
21erdheim-chester disease10.5CD40LG, TNF
22beach ear10.5CRP, F2
23stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features10.5IL1B, TNF
24peyronie's disease10.5IL1B, TNF
25drug-induced mental disorder10.5HLA-DRB1, IL10, TNF
26hypercementosis10.5HLA-DRB1, IL10, TNF
27cytoplasmic body myopathy10.5HLA-DRB1, IL10, TNF
28sjogren's syndrome10.5CD40LG, TNF
29progressive relapsing multiple sclerosis10.5HLA-DRB1, IL10, TNF
30esophagitis10.5CRP, F2
31oropouche fever10.5CD40LG, IL10
32tethered spinal cord syndrome10.5IL10, TLR2, TNF
33bartonellosis10.5CD40LG, TLR2
34brucella melitensis brucellosis10.5CD40LG, TNF
35protein r deficiency10.5IL1B, TLR2
36degenerative disc disease10.4IL10, TLR2, TNF
37hard palate cancer10.4IL10, TLR2, TNF
38askin's tumor10.4CRP, F2
39opisthorchiasis10.4IL10, TNF
40waardenburg syndrome type 410.4IL1B, TNF
41intermediate dend syndrome10.4IL6, TNF
42crohn's disease10.4IL6, TNF
43hydronephrosis10.4F2, IL10, TNF
44dysgammaglobulinemia10.4CD40LG, IL10
45fowler's syndrome10.4CD40LG, F2
46malignant sertoli-leydig cell tumor of ovary10.4IL6, TNF
47liver failure acute infantile10.4CD40LG, F2
48spinocerebellar ataxia 1810.4IL10, SLC9A3
49anti-hla hyperimmunization10.4TLR2, TNF
50withdrawal disorder10.4CRP, TLR2, TNF

Comorbidity relations with Leptospirosis via Phenotypic Disease Network (PDN):


Deficiency AnemiaAcute Kidney Failure
Chronic Kidney FailureFamilial Atrial Fibrillation
Heart DiseaseAcute Cystitis

Graphical network of the top 20 diseases related to Leptospirosis:



Diseases related to leptospirosis

Symptoms for Leptospirosis

About this section

Symptoms:

 10
  • jaundice
  • chills
  • fever
  • muscle pain
  • hepatomegaly

UMLS symptoms related to Leptospirosis:


nail bed hemorrhage, mucosal haemorrhage, traumatic hematuria, cullen's sign, hemoptysis

Drugs & Therapeutics for Leptospirosis

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Drugs for Leptospirosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 147)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CitalopramapprovedPhase 449459729-33-82771
Synonyms:
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
1,3-dihydro[3,4]benzofuran-5-carbonitrile
1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
59729-33-8
AB00513896
AC-12214
AC1L1EFH
AE-641/00603021
Akarin
BPBio1_000929
BRD-A47598013-004-02-0
BSPBio_000843
Bonitrile
C07572
C20H21FN2O
CHEBI:3723
CHEMBL549
CID2771
CPD000465669
Celapram
Celexa
Celius
Ciazil
Cilift
Cipram
Cipramil
Ciprapine
Citabax
Citadur
Citadur (TN)
Citalec
Citalopram
Citalopram (USP/INN)
Citalopram Hydrobromide
Citalopram [Celexa]
Citalopram [INN:BAN]
Citalopram hydrobromide
Citalopramum
Citalopramum [INN-Latin]
 
Citol
Citopam
Citox
Citrol
Cytalopram
D07704
DB00215
Dalsan
EINECS 261-891-1
Elopram
HMS2090O09
HMS2093A14
Humorup
I01-0382
InChI=1/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
L001223
LS-84327
Lopac0_000258
Lu 10-171
Lu-10-171
MolPort-003-666-794
NCGC00015267-07
NCGC00025160-02
Nitalapram
Oropram
Perrigo Citalopram
Pramcit
Prestwick3_000692
Recital
SAM002589960
ST069372
STL058639
Seropram
Talam
Talohexal
Temperax
UNII-0DHU5B8D6V
Vodelax
Zentius
Zetalo
[3H]Citalopram
citalopram
2
NorepinephrineapprovedPhase 459551-41-2439260
Synonyms:
(-)-(R)-Norepinephrine
(-)-Arterenol
(-)-Arterenol free base
(-)-NORADRENALINE
(-)-Noradrenaline
(-)-Norepinephrine
(-)-alpha-(Aminomethyl)protocatechuyl alcohol
(R)-(-)-Norepinephrine
(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
(R)-4-(2-amino-1-Hydroxyethyl)-1,2-benzenediol
(R)-Noradrenaline
(R)-Norepinephrine
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)- (9CI)
4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
4899-05-2
51-40-1 (l-tartrate (1:1))
51-41-2
66197-73-7
A7257_SIGMA
AC1L96ZT
ALBB-006229
Adrenor
Aktamin
Arterenol
BRN 4231961
BSPBio_002079
C00547
CHEBI:18357
CHEMBL1437
CID439260
D-(-)-Noradrenaline
D00076
D53D5E3A-2360-4CA9-8031-6C2CD4062FD5
DB00368
DivK1c_000230
EINECS 200-096-6
HMS1920B08
HMS2089E18
HMS2091J08
HMS500L12
IDI1_000230
KBio1_000230
KBio2_001489
KBio2_004057
KBio2_006625
KBio3_001579
KBioGR_000635
KBioSS_001489
L-2-Amino-1-(3,4-dihydroxyphenyl)ethanol
L-3,4-Dihydroxyphenylethanolamine
L-3,4-dihydroxyphenylethanolamine
L-Arterenol
L-Noradrenaline
L-Norepinephrine
L-alpha-(Aminomethyl)-3,4-dihydroxybenzyl alcohol
L-alpha-(aminomethyl)-3,4-dihydroxybenzyl alcohol
L-arterenol
L-noradrenaline
LS-42676
 
LT03330026
LT4
Levarterenol
Levarterenolo
Levarterenolo [DCIT]
Levoarterenol
Levonor
Levonoradrenaline
Levonorepinephrine
Levophed
NCGC00159406-02
NCGC00159406-03
NCGC00159406-04
NCGC00159406-05
NCGC00159406-06
NCGC00159406-07
NCGC00159406-09
NINDS_000230
Nor adrenalin
Nor adrenalin (TN)
Nor-Epirenan
Noradrenalin
Noradrenalina
Noradrenalina [Italian]
Noradrenaline
Noradrenaline (JP15)
Noradrenalinum
Norartrinal
Noreinefrina
Noreinefrina [INN-Spanish]
Norepinefrina
Norepinephrine
Norepinephrine (INN)
Norepinephrine Noradrenalin
Norepinephrine [INN:JAN]
Norepinephrine l-Tartrate (1:1)
Norepinephrinum
Norepinephrinum [INN-Latin]
Norepirenamine
PDSP1_001111
PDSP2_001095
SGCUT00123
SPBio_001048
SPECTRUM1500436
STK503776
Spectrum2_001064
Spectrum3_000520
Spectrum4_000078
Spectrum5_001068
Spectrum_001009
Sympathin E
UNII-X4W3ENH1CV
bmse000404
l-1-(3,4-Dihydroxyphenyl)-2-aminoethanol
l-2-Amino-1-(3,4-dihydroxyphenyl)ethanol
nchembio.284-comp2
nchembio.64-comp2
nchembio705-1
noradrenaline
norepinefrina
norepinephrine
norepinephrinum
to_000024
3
FluoxetineapprovedPhase 422954910-89-33386
Synonyms:
(+) or (-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine
(+) or (-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
(+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine
(+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine
(+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
(+/-)-Fluoxetine
(+/-)-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine
(+/-)-N-Methyl-3-p-(p-trifluoromethylphenoxy)-3-phenylpropylamine
(+/-)-N-Methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine
(+/-)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine]
(+/-)-N-Methyl-gamma-[4-(trifluoromethyl)phenoxy]benzenepropanamine
3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine
52341-67-0
54910-89-3
57226-07-0
59333-67-4 (hydrochloride)
AB00053774
AC-14564
AC1L1FTH
AKOS003663021
Adofen
Animex-On
BPBio1_000354
BPBio1_000509
BRD-A31159102-001-01-9
BRD-A31159102-003-05-6
BSPBio_000461
BSPBio_003375
Bio-0787
Biomol-NT_000152
C17H18F3NO
CHEBI:5118
CHEMBL41
CID3386
D00326
DB00472
Deprex
DivK1c_006819
Eufor
Floxetine
Fluctin
Fluoxeren
Fluoxetin
Fluoxetina
Fluoxetina [INN-Spanish]
Fluoxetina [Spanish]
Fluoxetine
Fluoxetine (TN)
Fluoxetine (USAN/INN)
Fluoxetine Hcl
Fluoxetine Hydrochloride
Fluoxetine [USAN:INN:BAN]
Fluoxetinum
 
Fluoxetinum [INN-Latin]
Fluoxétine
Fluval
Fontex
Foxetin
HMS2090H14
KBio1_001763
KBio2_002159
KBio2_004727
KBio2_007295
KBio3_002595
KBioGR_001166
KBioSS_002159
L000931
LS-31040
Lilly-110140
Lopac0_000558
Methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine
Methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine
MolPort-001-683-482
N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine
N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
N-methyl-3-phenyl-3-{[4-(trifluoromethyl)phenyl]oxy}propan-1-amine
NCGC00015428-10
NCGC00024879-03
NCGC00024879-04
NSC283480
Portal
Prestwick0_000511
Prestwick1_000511
Prestwick2_000511
Prestwick3_000511
Prozac
Prozac Weekly
Pulvules
Reconcile
Reneuron
SPBio_001815
SPBio_002382
STK734483
Sarafem
SpecPlus_000723
Spectrum2_001658
Spectrum3_001648
Spectrum4_000613
Spectrum5_001518
Spectrum_001679
TL8003595
UNII-01K63SUP8D
dl-3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine
fluoxetine
fluoxetine (Prozac)
nchembio.534-comp2
4Immunologic FactorsPhase 418483
5Immunosuppressive AgentsPhase 410422
6Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 118510
7Neurotransmitter AgentsPhase 414795
8ParasympatholyticsPhase 4902
9Serotonin AgentsPhase 42668
10Antidepressive AgentsPhase 42367
11Venlafaxine HydrochloridePhase 4185
12Serotonin Uptake InhibitorsPhase 41369
13Serotonin and Noradrenaline Reuptake InhibitorsPhase 4391
14
SerotoninPhase 4314750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
15Psychotropic DrugsPhase 45501
16Cholinergic AntagonistsPhase 41423
17Antiparkinson AgentsPhase 41312
18Neurotransmitter Uptake InhibitorsPhase 42857
19Antidepressive Agents, Second-GenerationPhase 41087
20Cytochrome P-450 CYP2D6 InhibitorsPhase 4602
21Cholinergic AgentsPhase 43243
22Muscarinic AntagonistsPhase 4961
23Cytochrome P-450 Enzyme InhibitorsPhase 43036
24Fingolimod HydrochloridePhase 486
25
Dexamethasoneapproved, investigationalPhase 2, Phase 3, Phase 1190950-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Baycadron
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
Dexameth
Dexamethansone
 
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone acetate
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone sodium phosphate
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamethsone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
Ozurdex
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
26
DalteparinapprovedPhase 32819041-08-1
Synonyms:
Daltepariininatrium
Dalteparin Sodyum
Dalteparin sodium
Dalteparin sodná sůl
Dalteparin-nátrium
Dalteparina sódica
 
Dalteparinnatrium
Dalteparino natrio druska
Dalteparinum Natricum
Dalteparyna sodowa
Daltéparine sodique
Fragmin
Heparin Fragment KABI 2165
Tedelparin
27
Temozolomideapproved, investigationalPhase 366285622-93-15394
Synonyms:
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide
3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-1,2,3,5-tetrazine-8-carboxamide
3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-as-tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-D)(1,2,3,5)tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide
3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
8-Carbamoyl-3-methylimidazo(5,1-D)-1,2,3,5-tetrazin-4(3H)-one
8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one
85622-93-1
AC-758
AC1L1K9B
BIDD:GT0204
BRN 5547136
Bio-0147
C047246
C6H6N6O2
CCRG 81045
CCRG-81045
CCRIS 8996
CHEBI:153686
CHEMBL810
CID5394
CPD000466338
D06067
DB00853
Essex brand of temozolomide
HMS2051O12
HMS2090B08
I06-0149
I14-1943
LS-80558
M B 39831
M & B 39831
M&B 39831
M&B-39831
 
M-39831
MB 39831
MLS000759447
MLS001424028
MLS002701861
Methazolastone
NCGC00167429-01
NCGC00167429-02
NCI60_003316
NSC 362856
NSC-362856
NSC362856
SAM001246636
SMR000466338
STK623541
Sch 52365
Sch-52365
Schering brand of temozolomide
Schering-Plough brand of temozolomide
TL8005593
TMZ
TMZ-Bioshuttle
Temodal
Temodal (TN)
Temodar
Temozolamide
Temozolodida
Temozolodida [Spanish]
Temozolomid
Temozolomida
Temozolomide
Temozolomide (JAN/USAN/INN)
Temozolomide [INN:BAN]
Temozolomidum
Temozolomidum [Latin]
Témozolomide
UNII-YF1K15M17Y
ZINC01482184
m & b 39831
temozolomide
28
ApixabanapprovedPhase 3111503612-47-310182969
Synonyms:
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahyd
2p16
503612-47-3
AKOS005146204
Apixaban
Apixaban (JAN/USAN/INN)
Apixabanum
BMS 562247-01
BMS-562247
BMS-562247-01
 
BMS-562247-01, Apixaban
CHEBI:49620
CHEMBL231779
CID10182969
D03213
DB07828
Eliquis
GG2
S1593_Selleck
UNII-3Z9Y7UWC1J
ro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid amide
29Antineoplastic Agents, HormonalPhase 2, Phase 3, Phase 14256
30Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 2, Phase 3, Phase 19988
31BB 1101Phase 2, Phase 3, Phase 11909
32Gastrointestinal AgentsPhase 2, Phase 3, Phase 16401
33Anti-Inflammatory AgentsPhase 2, Phase 3, Phase 18478
34glucocorticoidsPhase 2, Phase 3, Phase 13896
35Dexamethasone acetatePhase 2, Phase 3, Phase 119091177-87-3
36Dexamethasone 21-phosphatePhase 2, Phase 3, Phase 11909
37HormonesPhase 2, Phase 3, Phase 111748
38AnticoagulantsPhase 31760
39HIV Protease InhibitorsPhase 3, Phase 2, Phase 14558
40AntithrombinsPhase 3574
41Antithrombin IIIPhase 3563
42Hormone AntagonistsPhase 2, Phase 3, Phase 110002
43AntiemeticsPhase 2, Phase 3, Phase 13213
44Protease InhibitorsPhase 3, Phase 2, Phase 14558
45Liver ExtractsPhase 33572
46Serine Proteinase InhibitorsPhase 3705
47Factor Xa InhibitorsPhase 3315
48Heparin, Low-Molecular-WeightPhase 3286
49VasopressinsPhase 2, Phase 3260
50Natriuretic AgentsPhase 2, Phase 31403

Interventional clinical trials:

(show top 50)    (show all 61)
idNameStatusNCT IDPhase
1Plantar Fasciosis Treatment Using CoblationCompletedNCT00189592Phase 4
2Combination of Antidepressants and Fingolimod Relapsing-remitting Multiple Sclerosis (RRMS) Patients With DepressionTerminatedNCT01436643Phase 4
3Evaluation of the Use of Apixaban in Prevnetion of Thromboembolic Disease in Patients With Myeloma Trated With iMiDsRecruitingNCT02066454Phase 3
4Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in GlioblastomaRecruitingNCT02546102Phase 3
5Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal CancerRecruitingNCT01483027Phase 3
6Desmopressin and Dexamethasone Adjunctive Treatment for LeptospirosisTerminatedNCT00592566Phase 2, Phase 3
7Efficacy and Safety Study in the Treatment of Chronic Diabetic Foot UlcersTerminatedNCT00387101Phase 3
8Investigation of Cogane (PYM50028) in Early-stage Parkinson's Disease (CONFIDENT-PD)CompletedNCT01060878Phase 2
9Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based ChemotherapyCompletedNCT00318370Phase 2
10The CareFUL Prevention TrialCompletedNCT00803608Phase 2
11Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot UlcersCompletedNCT02119754Phase 2
12Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot UlcersCompletedNCT02091596Phase 2
13Repeat-Dose of Forodesine Hydrochloride (BCX-1777) Infusion in Patients With Advanced T-Cell LeukemiaCompletedNCT00095381Phase 2
14An Open Label Extension Study of the Efficacy of MORAb-003CompletedNCT01018563Phase 2
15A Study Comparing Eribulin Mesylate and Ixabepilone in Causing or Exacerbating Neuropathy in Patients With Advanced Breast CancerCompletedNCT00879086Phase 2
16SPYRAL HTN-ON MED StudyRecruitingNCT02439775Phase 2
17SPYRAL HTN-OFF MED StudyRecruitingNCT02439749Phase 2
18A Study to Assess the Efficacy and Safety of Farletuzumab (MORAb 003) in Combination With Carboplatin Plus Paclitaxel or Carboplatin Plus Pegylated Liposomal Doxorubicin (PLD) in Subjects With Low CA125 Platinum-Sensitive Ovarian CancerRecruitingNCT02289950Phase 2
19Open-Label, Dose Escalation Study of PRTX-100 in Adults With Persistent/Chronic Immune ThrombocytopeniaRecruitingNCT02401061Phase 1, Phase 2
20A Study of AG-348 in Adult Patients With Pyruvate Kinase DeficiencyRecruitingNCT02476916Phase 2
21Safety Study of the Proteasome Inhibitor PR-171 (Carfilzomib for Injection) in Patients With Hematological MalignanciesCompletedNCT00150462Phase 1
22Safety Study of Farletuzumab, Carboplatin and Pegylated Liposomal Doxorubicin (PLD) to Treat Platinum-sensitive Ovarian CancerCompletedNCT01004380Phase 1
23A Study of MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung CancerCompletedNCT00325494Phase 1
24Safety Study of AZD5672 in Renally Impaired SubjectsCompletedNCT00715702Phase 1
25The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon IslandsCompletedNCT01080989
26Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS)CompletedNCT00562094
27Non-interventional Observational Study on WHO-5 Questionnaire Application in Parkinson's DiseaseCompletedNCT00752388
28Caregivers' and Physicians' Treatment Preference in Parkinson Patients Treated With Neupro® Requiring Caregiver SupportCompletedNCT01330290
29Intraoperative Three Dimensional Fluoroscopy Compared to Standard Fluoroscopy for the Assessment of Reduction of Ankle Fractures With Syndesmosis DisruptionCompletedNCT00556010
30BIOmarkers of Dyspnea IN Emergency RoomCompletedNCT01227317
31Study for a Rational Management of Appendicitis in ChildrenCompletedNCT01067937
32Observational Non-interventional Study (Anwendungsbeobachtung) With Telmisartan in High-risk HypertensivesCompletedNCT00539487
33Quality of Life in Daxas-treated Patients Older Than 18 Years With Severe COPDCompletedNCT01285180
34Fluid Challenges in Intensive CareCompletedNCT01787071
35Persistence, Adherence, Quality of Life, and Treatment Satisfaction With Avonex® PEN™.CompletedNCT01405872
36Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness WoundsCompletedNCT00971048
37Dabigatran Etexilate for Stroke Prevention in Patients With Atrial Fibrillation and Mild to Moderate Renal ImpairmentCompletedNCT01721837
38Three Injections of EUFLEXXA (Sodium Hyaluronate) for Treatment of Chronic Shoulder Pain Associated With Osteoarthritis (OA)CompletedNCT00969501
39Chemotherapeutic Agents in Brain/BreastCompletedNCT00795678
40The Effect of Foot Orthoses on the Braking Response TimeCompletedNCT02354066
41French West Indies Leptospirosis StudyRecruitingNCT01607047
42Study of Decreasing Kinetics of the Leptospiremia During Antibiotic Treatment of Leptospirosis in MartiniqueRecruitingNCT02000635
43Prospective, Study for the Use of Palivizumab (Synagis) in High Risk Children in GermanyRecruitingNCT01155193
44Renal Nerve Ablation in Chronic Kidney Disease PatientsRecruitingNCT01442883
45Safety Follow-up Study in Subjects With Silicone Gel-filled Breast Implants as Compared Both to Saline-filled Breast Implants and to National NormsRecruitingNCT00443274
46Immune Tests in Blood Samples From Children With ASDRecruitingNCT02168868
47Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial InfectionsRecruitingNCT00502476
48Concentration and Activity of Lapatinib in Vestibular SchwannomasRecruitingNCT00863122Phase 0
49Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)RecruitingNCT02032043
50Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for LiberiaRecruitingNCT01905436

Search NIH Clinical Center for Leptospirosis


Cochrane evidence based reviews: leptospirosis

Genetic Tests for Leptospirosis

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Anatomical Context for Leptospirosis

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MalaCards organs/tissues related to Leptospirosis:

33
Lung, Kidney, Heart, Liver, Testes, Breast, Thyroid

Animal Models for Leptospirosis or affiliated genes

About this section

MGI Mouse Phenotypes related to Leptospirosis:

38 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.4AQP1, CD40LG, IL6, SLC12A1, SLC9A3, TLR2
2MP:00053818.3F2, IL10, IL6, SLC9A3, TLR2, TNF
3MP:00053888.3AQP1, F2, IL10, IL6, TLR2, TNF
4MP:00053798.2AQP1, CD40LG, IL10, IL6, SLC9A3, TLR2
5MP:00053897.7AQP1, CD40LG, F2, IL10, IL6, SLC12A1
6MP:00107717.6CD40LG, F2, IL10, IL1B, IL6, SLC12A1
7MP:00053907.1CD40LG, F2, IL10, IL1B, IL6, SLC12A1
8MP:00053976.8AQP1, CD40LG, F2, IL10, IL1B, IL6
9MP:00053876.3CCL2, CD40LG, CRP, F2, IL10, IL1B
10MP:00053766.3AQP1, CD40LG, CRP, F2, IL10, IL1B
11MP:00053856.1AQP1, CD40LG, CRP, F2, IL10, IL1B

Publications for Leptospirosis

About this section

Articles related to Leptospirosis:

(show top 50)    (show all 658)
idTitleAuthorsYear
1
Atypical leptospirosis: an overlooked cause of aseptic meningitis. (26964740)
2016
2
Leptospirosis: a report on a series of five autochthonous cases in a Greek region. (26430953)
2015
3
Renewing the momentum for leptospirosis research in Africa. (26385934)
2015
4
Atypical manifestations of leptospirosis. (25813883)
2015
5
Whole-Genome Sequence of Leptospira interrogans Serovar Hardjo Subtype Hardjoprajitno Strain Norma, Isolated from Cattle in a Leptospirosis Outbreak in Brazil. (26543126)
2015
6
Meta-Analyses of Factors Associated with Leptospirosis in Domestic Dogs. (26515048)
2015
7
Seroprevalence study of leptospirosis among rice farmers in khuzestan province, South west iran, 2012. (25368799)
2014
8
Seroepidemiology of leptospirosis in dogs and rats in Trinidad. (25776612)
2014
9
Leptospirosis in sheep and goats under tropical conditions. (24085419)
2013
10
Signalment Changes in Canine Leptospirosis between 1970 and 2009. (24372922)
2013
11
Outbreak of leptospirosis among canyoning participants, Martinique, 2011. (23725775)
2013
12
Molecular typing of Leptospira spp. strains isolated from field mice confirms a link to human leptospirosis. (23406882)
2013
13
A conserved region of leptospiral immunoglobulin-like A and B proteins as a DNA vaccine elicits a prophylactic immune response against leptospirosis. (23486420)
2013
14
Plasma exchange in severe leptospirosis with multi-organ failure: a case report. (23809518)
2013
15
Antimicrobial Prophylaxis For Melioidosis and Leptospirosis For At Risk Rescue Workers. (23466779)
2013
16
Severe Pulmonary Involvement in Leptospirosis: Alternate antibiotics and systemic steroids. (23862041)
2013
17
Flock-level risk factors associated with leptospirosis in dairy goats in a semiarid region of Northeastern Brazil. (23031326)
2013
18
Human hemorrhagic pulmonary leptospirosis: pathological findings and pathophysiological correlations. (23951234)
2013
19
Microhaemorrhages in Leptospirosis on susceptibility weighted imaging. (22285590)
2012
20
Modeling seasonal leptospirosis transmission and its association with rainfall and temperature in Thailand using time-series and ARIMAX analyses. (22647816)
2012
21
Prolonged jaundice attributed to super infection of hepatitis E virus in a case of resolving leptospirosis. (22361773)
2012
22
The dog in the transmission of human leptospirosis under tropical conditions: victim or villain? (21396149)
2012
23
Evaluation of 'white-spotted kidneys' associated with leptospirosis by polymerase chain reaction based LipL32 gene in slaughtered cows. (23327135)
2012
24
Cases distribution of leptospirosis in City of Manaus, State of Amazonas, Brazil, 2000-2010. (23295874)
2012
25
Serology and PCR for bovine leptospirosis: herd and individual approaches. (22427387)
2012
26
Outbreak of melioidosis and leptospirosis co-infection following a rescue operation. (23082420)
2012
27
Severe leptospirosis in a Dutch traveller returning from the Dominican Republic, October 2011. (22490382)
2012
28
Leptospirosis diagnosis by immunocapture polymerase chain reaction: a new tool for early diagnosis and epidemiologic surveillance. (22770775)
2012
29
A sensitive and specific IgM-ELISA for the serological diagnosis of human leptospirosis using a rLipL32/1-LipL21-OmpL1/2 fusion protein. (21784316)
2011
30
Vaccination for leptospirosis improved the weaning percentage of 2-year-old farmed red deer hinds in New Zealand. (21660849)
2011
31
Sporadic urban leptospirosis. (23882321)
2011
32
Travel-related leptospirosis in Israel: a nationwide study. (20207873)
2010
33
Differential cytokine gene expression according to outcome in a hamster model of leptospirosis. (20076757)
2010
34
The contribution of bats to leptospirosis transmission in Sao Paulo City, Brazil. (20134010)
2010
35
Evaluation of a recombinant LigB protein of Leptospira interrogans serovar Canicola in an enzyme-linked immunosorbent assay for the serodiagnosis of bovine leptospirosis. (20022618)
2010
36
Serodiagnosis of bovine leptospirosis by IgG-enzyme-linked immunosorbent assay and latex agglutination test. (19680775)
2010
37
Leptospirosis-associated acute kidney injury. (21541455)
2010
38
Leptospirosis pulmonary haemorrhage syndrome is associated with linear deposition of immunoglobulin and complement on the alveolar surface. (19778300)
2010
39
Seasonal and environmental determinants of leptospirosis and scrub typhus in small mammals captured at a U.S. military training site (Dagmar North), Republic of Korea, 2001-2004. (19891218)
2009
40
Leptospirosis distribution related to freshwater habitats in the Vojvodina region (Republic of Serbia). (19911133)
2009
41
Evaluation of surveillance case definition in the diagnosis of leptospirosis, using the Microscopic Agglutination Test: a validation study. (19386085)
2009
42
Leptospirosis: a worldwide resurgent zoonosis and important cause of acute renal failure and death in developing nations. (19484873)
2009
43
Increase in seroprevalence of canine leptospirosis and its risk factors, Ontario 1998-2006. (19794888)
2009
44
Acute acalculous cholecystitis in leptospirosis. (10509958)
1999
45
Leptospirosis with acute acalculous cholecystitis and pancreatitis. (8421147)
1993
46
Occurrence of antibodies to the etiologic agents of infectious bovine rhinotracheitis, parainfluenza 3, leptospirosis, and brucellosis in white-tailed deer in Minnesota. (3005666)
1986
47
48
49
50

Variations for Leptospirosis

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Expression for genes affiliated with Leptospirosis

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Search GEO for disease gene expression data for Leptospirosis.

Pathways for genes affiliated with Leptospirosis

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Pathways related to Leptospirosis according to GeneCards Suite gene sharing:

(show all 39)
idSuper pathwaysScoreTop Affiliating Genes
19.3CD40LG, IL1B, TNF
29.2IL10, IL1B, TNF
39.0IL1B, IL6
49.0CCL2, IL1B, TNF
5
Show member pathways
9.0CD40LG, IL1B, TLR2, TNF
69.0IL10, IL6, TNF
7
Show member pathways
8.7IL1B, IL6, TLR2
88.7CCL2, IL1B, TLR2, TNF
98.7IL1B, IL6, TNF
108.5CD40LG, IL10, IL6, TLR2, TNF
118.4IL1B, IL6, TLR2, TNF
12
Show member pathways
8.4IL1B, IL6, TLR2, TNF
13
Show member pathways
8.4IL10, IL1B, IL6, TNF
148.4IL10, IL1B, IL6, TNF
158.4IL10, IL1B, IL6, TNF
168.4IL10, IL1B, IL6, TNF
178.4IL10, IL1B, IL6, TNF
188.2HLA-DRB1, IL1B, IL6, TNF
198.2CCL2, IL1B, IL6, TNF
208.2CCL2, IL1B, IL6, TNF
21
Show member pathways
8.2CCL2, IL1B, IL6, TNF
22
Show member pathways
8.2CD40LG, IL1B, IL6, TLR2, TNF
23
Show member pathways
8.1CD40LG, HLA-DRB1, IL10, IL1B, TLR2, TNF
24
Show member pathways
8.1CD40LG, IL10, IL1B, IL6, TNF
25
Show member pathways
8.1IL10, IL1B, IL6, TLR2, TNF
268.1IL10, IL1B, IL6, TLR2, TNF
278.1IL10, IL1B, IL6, SLC9A3, TNF
287.8HLA-DRB1, IL10, IL1B, IL6, TNF
297.8AQP1, CCL2, IL1B, IL6, TNF
30
Show member pathways
7.6CCL2, CD40LG, IL10, IL1B, IL6, TNF
317.6HLA-DRB1, IL10, IL1B, IL6, TLR2, TNF
32
Show member pathways
7.6CCL2, IL10, IL1B, IL6, TLR2, TNF
33
Show member pathways
7.5CCL2, F2, IL10, IL1B, IL6, TNF
34
Show member pathways
7.4CCL2, HLA-DRB1, IL1B, IL6, TLR2, TNF
357.4CCL2, HLA-DRB1, IL1B, IL6, TLR2, TNF
36
Show member pathways
7.4CCL2, CRP, F2, IL1B, IL6, TNF
37
Show member pathways
7.3CD40LG, HLA-DRB1, IL10, IL1B, IL6, TLR2
387.3CCL2, CD40LG, IL10, IL1B, IL6, TLR2
39
Show member pathways
7.3CCL2, CD40LG, IL10, IL1B, IL6, TLR2

GO Terms for genes affiliated with Leptospirosis

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Cellular components related to Leptospirosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.9CD40LG, HLA-DRB1, IL6

Biological processes related to Leptospirosis according to GeneCards Suite gene sharing:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1regulation of immunoglobulin secretionGO:005102310.6CD40LG, TNF
2positive regulation of chemokine productionGO:003272210.6TLR2, TNF
3receptor biosynthetic processGO:003280010.5IL10, TNF
4negative regulation of cytokine secretion involved in immune responseGO:000274010.5IL10, TNF
5negative regulation of growth of symbiont in hostGO:004413010.4IL10, TNF
6negative regulation of interleukin-6 productionGO:003271510.4IL10, TNF
7response to inactivityGO:001485410.3F2, IL10
8positive regulation of nitric-oxide synthase biosynthetic processGO:005177010.3CCL2, TLR2
9positive regulation of collagen biosynthetic processGO:003296710.3CCL2, F2
10positive regulation of calcidiol 1-monooxygenase activityGO:006055910.2IL1B, TNF
11positive regulation of membrane protein ectodomain proteolysisGO:005104410.2IL1B, TNF
12sequestering of triglycerideGO:003073010.2IL1B, TNF
13regulation of establishment of endothelial barrierGO:190314010.2IL1B, TNF
14positive regulation of chemokine biosynthetic processGO:004508010.2IL1B, TNF
15positive regulation of NF-kappaB import into nucleusGO:004234610.2IL1B, TNF
16positive regulation of fever generationGO:003162210.2IL1B, TNF
17negative regulation of lipid catabolic processGO:005099510.2IL1B, TNF
18negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.1IL1B, TNF
19regulation of I-kappaB kinase/NF-kappaB signalingGO:004312210.1IL1B, TNF
20epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.0IL6, TNF
21positive regulation of phagocytosisGO:005076610.0IL1B, TNF
22defense response to protozoanGO:004283210.0IL10, IL6
23negative regulation of lipid storageGO:00108889.9IL6, TNF
24response to antibioticGO:00466779.8CCL2, IL6
25response to gamma radiationGO:00103329.8CCL2, IL1B
26cellular response to hepatocyte growth factor stimulusGO:00357299.7IL10, IL6
27positive regulation of JUN kinase activityGO:00435079.4IL1B, TNF
28lipopolysaccharide-mediated signaling pathwayGO:00316639.4CCL2, IL1B, TLR2
29leukocyte migrationGO:00509009.4F2, IL1B, TNF
30positive regulation of nitric oxide biosynthetic processGO:00454299.4IL1B, IL6, TNF
31response to woundingGO:00096119.2CCL2, F2, IL6
32defense response to Gram-positive bacteriumGO:00508309.2CRP, IL6, TLR2, TNF
33regulation of cell shapeGO:00083609.1CCL2, F2, IL6
34positive regulation of interleukin-6 productionGO:00327559.1IL1B, IL6, TNF
35positive regulation of apoptotic processGO:00430659.1IL1B, IL6, TNF
36cellular response to dexamethasone stimulusGO:00715498.9AQP1, CCL2, IL6
37negative regulation of apoptotic processGO:00430668.9AQP1, CD40LG, IL10, IL6
38positive regulation of ERK1 and ERK2 cascadeGO:00703748.9CCL2, IL1B, IL6
39positive regulation of sequence-specific DNA binding transcription factor activityGO:00510918.9IL10, IL1B, IL6, TNF
40positive regulation of transcription, DNA-templatedGO:00458938.8IL10, IL1B, IL6, TNF
41positive regulation of NF-kappaB transcription factor activityGO:00510928.8CD40LG, IL1B, IL6, TNF
42agingGO:00075688.5CCL2, IL10, IL1B, IL6
43response to heatGO:00094088.5CCL2, IL1B, IL6
44cytokine-mediated signaling pathwayGO:00192218.5CCL2, HLA-DRB1, IL1B, IL6
45response to lipopolysaccharideGO:00324968.4IL10, IL1B, IL6
46cellular response to lipopolysaccharideGO:00712228.3CCL2, IL1B, IL6, TNF
47inflammatory responseGO:00069548.2CRP, IL10, IL1B, IL6, TNF
48response to glucocorticoidGO:00513848.1CCL2, IL10, IL1B, IL6, SLC9A3, TNF
49response to drugGO:00424938.0AQP1, CCL2, IL10, IL1B, IL6
50immune responseGO:00069557.2CCL2, HLA-DRB1, IL10, IL1B, IL6, TLR2

Sources for Leptospirosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet