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Leukemia malady
11 drugs, 3308 genes, 48 tissues, 987 related diseases, 29 phenotypes, 12654 articles, clinical trials.

Summaries for Leukemia

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6Disease Ontology, 23MedlinePlus, 44Wikipedia, 22MalaCards
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MedlinePlus: Leukemia is cancer of the white blood cells. white blood cells help your body fight infection. your blood cells form in your bone marrow. in leukemia, however, the bone marrow produces abnormal white blood cells. these cells crowd out the healthy blood cells, making it hard for blood to do its work. there are different types of leukemia, including acute lymphocytic leukemia acute myeloid leukemia chronic lymphocytic leukemia chronic myeloid leukemia leukemia can develop quickly or slowly. chronic leukemia grows slowly. in acute leukemia, the cells are very abnormal and their number increases rapidly. adults can get either type; childen with leukemia most often have an acute type. some leukemias can often be cured. other types are hard to cure, but you can often control them. treatments may include chemotherapy, radiation and stem cell transplantation. even if symptoms disappear, you might need therapy to prevent a relapse. nih: national cancer institute23

MalaCards: Leukemia is related to carcinoma and prostatitis. An important gene associated with Leukemia is MLL (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)), and among its related pathways are MAPK Signaling and Akt Signaling. The drugs isotretinoin and pipobroman and the compounds estrogen and ethanol have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, whole blood and lymph node, and related mouse phenotypes are vision/eye and growth/size.

Disease Ontology: A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.6

Wikipedia: Leukemia (American English) or leukaemia (British English) (from the Ancient Greek λευκός leukos...44 more...

Aliases & Descriptions for Leukemia

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6Disease Ontology, 7diseasecard, 8DISEASES, 32Novoseek , 23MedlinePlus, 43UMLS, 40SNOMED-CT, 19ICD9CM, 27NCIt, 24MeSH
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Aliases & Descriptions:

leukemia 6 7 8 32 23 43

Related Diseases for Leukemia

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13GeneCards, 14GeneDecks
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Diseases related to leukemia by text searches and GeneDecks gene sharing:

(show top 50)    (show all 984)
idRelated DiseaseScoreTop Affiliating Genes
1carcinoma496.6ZNF382, ZNF673, ZNF124, ZNF384, PIK3CB, PIK3CD
2prostatitis494.6ZNF673, PIK3CB, PIK3CD, PIM2, PIAS2, PIK3CA
3neuronitis467.4ZNF384, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2
4myeloid leukemia433.0ZNF673, ZNF296, PIK3CB, PIK3CD, PIM2, PIK3CA
5pancreatitis404.1PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
6melanoma379.9PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
7adenocarcinoma376.0PIK3CB, PIM2, PIK3CA, PIK3R1, PIK3C2A, PIK3CG
8colorectal cancer372.9ZNF22, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2
9lymphocytic leukemia364.7PIK3CD, PIM2, PIK3CA, PIK3CG, PIGU, RFX7
10hepatocellular carcinoma354.1ZNF384, PIK3CB, PIK3CD, PIM2, PIK3CA, PIK3R1
11thyroiditis344.6PIK3CB, PIK3CA, PIK3R1, PICALM, PIK3C2A, PIK3CG
12arthritis325.1PIK3CD, PIBF1, PIK3CG, PIN1, LRP1, LRP5
13gastric cancer319.9ZNF580, PIK3CB, PIK3CA, PIK3R1, PIAS1, PIK3CG
14lymphoblastic leukemia311.2ZNF230, ZNF384, ZNF521, PIK3CA, PICALM, PIK3CG
15acute myeloid leukemia306.6ZNF673, ZNF296, PIK3CB, PIK3CD, PIM2, PIK3CA
16rheumatoid arthritis299.2PIK3CD, PIBF1, PIK3CG, PIN1, LRP1, LRP5
17colon cancer290.9PIK3CB, PIAS2, PIK3CA, PIK3R3, PIK3R1, PIAS1
18neuroblastoma285.9PIK3CB, PIK3CD, PIAS2, PIK3CA, PIK3R1, PIK3CG
19myeloma281.3PIM2, PIK3CA, PIK3R2, PIK3R1, PIK3CG, LRP1
20hypoxia279.8PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIAS4, PIK3C2A
21esophagitis276.4ZNF673, PIK3CB, PIK3CA, PIK3C2A, PIK3CG, PIN1
22cervicitis276.3ZNF384, PIK3CA, PIK3CG, PIN1, RFC1, NCL
23sarcoma272.6ZNF384, PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1
24alzheimer's disease262.0PIK3CB, PIK3CD, PIK3CA, PIK3R1, PICALM, PIK3CG
25cholesterol242.7PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, PIAS1
26fibrosis239.1PIK3CA, PIK3CG, PIN1, LRP1, KLF6, NCF2
27multiple myeloma231.3PIK3CA, PIK3R2, PIK3R1, PIK3CG, LRP1, NCAM1
28lupus erythematosus230.4PIK3CD, PIK3C2A, PIK3CG, SH2B3, COG2, NCF2
29retinitis226.1PIGA, PIK3CA, PIK3C2A, PIK3CG, PIM1, LRP1
30adenoma223.7PIK3CA, KLF4, NCAM1, NCF2, NCOA1, NCOA2
31cerebritis221.9PIK3R1, PIK3C2A, PIK3CG, LRP1, LRP6, COG2
32asthma219.5PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3CG, PIN1
33tuberculosis213.5PIM2, PIK3CG, PIM1, SH2D1A, NCR1, PDCD1
34acute leukemia212.2ZNF384, PIK3CA, PICALM, SH3GL1, NCAM1, NCL
35ovarian carcinoma209.3PIK3CA, PIK3CG, NCOA3, PDCD4, PDCD5, RECK
36non-hodgkin lymphoma202.2PIM2, PIK3CA, PIM1, SH2D1A, RFC1, NCF2
37squamous cell carcinoma199.6PIK3CB, PIK3CA, PIN1, PIM1, KLF4, NCL
38anemia197.7PIGA, PIM1, SH2D1A, KLF1, KLF2, RFX1
39hypertension196.1PIK3CB, PIK3R1, PIK3C2A, PIK3CG, PIM1, LRP1
40colon carcinoma194.8PIK3CB, PIK3CA, PIK3R2, PIK3R1, PIAS1, PIK3CG
41osteosarcoma194.5PIK3CB, PIK3CA, PIK3CG, LRP5, KLF10, RFC1
42lung carcinoma192.9PIK3CA, PIK3R1, PIK3CG, KLF6, NCAM1, RECK
43cervical cancer192.7PIK3CA, PIK3CG, PIN1, RFC1, NCL, NCR1
44obesity181.8PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, LRP1
45schizophrenia180.8ZNF124, ZNF230, PIK3CB, PIK3CA, PIK3R1, PIK3CG
46gonococcal synovitis180.8PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLF4
47pneumonia176.3PIK3C2A, COG2, PDE4A, RELA, REV1, VTN
48astrocytoma174.0PIK3CA, PIK3R1, PIK3CG, LRP1, KLF6, NCAM1
49breast carcinoma166.7PIK3CA, PIK3R1, PIK3CG, LRP1, LRPAP1, SH3GL2
50retinoblastoma166.2ZNF22, PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3CG

Graphical network of the top 20 diseases related to leukemia:



Graphical network of diseases related to leukemia

Clinical Features for Leukemia

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Drugs & Therapeutics for Leukemia

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

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Drug clinical trials:

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Inferred drug relations via UMLS/NDF-RT:

43 28 cytarabine, cytarabine liposome, doxorubicin hydrochloride, irinotecan, irinotecan hydrochloride, isotretinoin, methotrexate, methotrexate sodium, pipobroman, vincristine, vincristine sulfate

Genetic Tests for Leukemia

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Anatomical Context for Leukemia

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22MalaCards
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MalaCards organs/tissues related to leukemia:

22
Bone marrow, Whole blood, Lymph node, Spleen, Thymus, Brain, Cortex, Retina, Spinal cord, Heart, Smooth muscle, Skeletal muscle, Small intestine, Colon, Adipocyte, Kidney, Liver, Lung, Pancreas, Thyroid, Adrenal gland, Breast, Skin, Ovary, Uterus, Placenta, Prostate, Testis, Cervix, Myeloid, Monocytes, Nk cells, T cells, B lymphoblasts, B cells, Endothelial, Fetal brain, Prefrontal cortex, Cardiac myocytes, Tongue, Fetal liver, Fetal lung, Bronchial epithelium, Fetal thyroid, Adrenal cortex, Pituitary, Testis germ, Testis leydig

Phenotypes for genes affiliated with Leukemia

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MGI Mouse Phenotypes related to leukemia:

25 (show all 29)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1vision/eye phenotypeMP:0005391INFPIK3CA, PIN1, LRP5, LRP6, SH3BP2, NCAM1
2growth/size phenotypeMP:0005378INFZNF384, ZNF521, PIK3CB, PIGA, PIM2, PIK3CA
3respiratory system phenotypeMP:0005388INFLRP6, SH3BP2, KLF2, KLF5, NCKAP1L, REL
4homeostasis/metabolism phenotypeMP:0005376INFPIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, PICALM
5no phenotypic analysisMP:0003012INFPIK3CD, PIK3R1, LRP6, RFWD2, NCKIPSD, NCOA2
6mortality/agingMP:0010768INFPIK3CB, PIGA, PIK3CA, PIAS4, PIAS1, PICALM
7cardiovascular system phenotypeMP:0005385INFPIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, PIK3CG
8liver/biliary system phenotypeMP:0005370INFPICALM, LRP5, LRP6, SH3BP2, KLF1, KLF2
9tumorigenesisMP:0002006INFPIK3CB, PIGA, PIK3CA, PIK3R2, PIK3R1, PINX1
10integument phenotypeMP:0010771INFPIGA, PIK3CG, PIN1, PINX1, LRP6, SH3BP2
11limbs/digits/tail phenotypeMP:000537167.1LRP5, LRP6, KLF10, RECK, RELA, RELB
12hearing/vestibular/ear phenotypeMP:000537748.3LRP6, NCOA3, KIT, KITLG, SFN, RB1
13pigmentation phenotypeMP:000118634.2LRP5, RFWD2, PDE3B, KIT, KITLG, BTD
14other phenotypeMP:000539529.4LRPAP1, SH2B3, NCKAP1L, RECK, RELB, CNR1
15nervous system phenotypeMP:0003631INFPIGA, LRP1, LRP5, LRP6, LRPAP1, SH3BP2
16digestive/alimentary phenotypeMP:0005381INFPIGA, LRP6, SH3BP2, KLF4, KLF5, NCOA3
17adipose tissue phenotypeMP:0005375INFPIK3CA, PIK3R1, PIK3C2A, LRP1, LRP6, KLF3
18muscle phenotypeMP:0005369INFPIK3CA, PIK3R2, PIK3R1, PIK3CG, LRP1, SH3BP2
19hematopoietic system phenotypeMP:0005397INFPIGA, PIM2, PIAS4, PICALM, PINX1, PIM1
20embryogenesis phenotypeMP:0005380INFPIK3CB, PIGA, PIK3CA, PIR, PICALM, PINX1
21normal phenotypeMP:0002873INFPIAS2, PIK3R1, LRP1, LRP5, LRP6, LRPAP1
22reproductive system phenotypeMP:0005389INFZNF384, PIGA, PIK3CA, LRP6, LRPAP1, KLF4
23craniofacial phenotypeMP:0005382INFZNF521, PIGA, LRP5, LRP6, SH3BP2, KLF2
24behavior/neurological phenotypeMP:0005386INFPIGA, PIK3CA, LRP1, LRP5, LRP6, KLF4
25immune system phenotypeMP:0005387INFPIK3CD, PIM2, PIAS4, PIAS1, PIK3R5, PICALM
26renal/urinary system phenotypeMP:0005367INFLRP6, LRPAP1, KLF1, NCKAP1L, NCOA1, NCOA3
27cellular phenotypeMP:0005384INFPIK3CB, PIGA, PIK3CD, PIM2, PIK3CA, PIK3R1
28skeleton phenotypeMP:0005390INFZNF384, ZNF521, PIGA, PIK3CD, PIK3CG, LRP1
29endocrine/exocrine gland phenotypeMP:0005379INFZNF384, LRP5, LRPAP1, KLF4, KLF5, RFWD2

Publications for genes affiliated with Leukemia

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35PubMed
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Articles related to leukemia:

(show top 50)    (show all 12654)
idTitleAuthorsYearAffiliating Genes
1Hemophagocytosis associated with leukemia: a striking association with juvenile myelomonocytic leukemia. (19798502)Unal S.... Gurgey A.2010PTPN11
2A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia. (20935257)Such E.... Sanz M.A.2010NUP98
3Prognostic importance of MN1 transcript levels, and b iologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B s tudy. (19451432)Langer C.... Bloomfield C.D.2009MN1
4RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation. (19282830)Kuo M.C.... SHIH L.Y.2009RUNX1
5PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients. (18830259)Kozako T.... Arima N.2009PDCD1, CD274
6Clinical and biological characteristics of adult biph enotypic acute leukemia in comparison with that of acute myeloid leukemia and a cute lymphoblastic leukemia: a case series of a Chinese population. (19454497)Xu X.Q.... Qiu H.Y.2009CD34
7Determination of Ras-GTP and Ras-GDP in patients with acute myelogenous leukemia (AML), myeloproliferative syndrome (MPS), juvenile myelomonocytic leukemia (JMML), acute lymphocytic leukemia (ALL), and malignant lymphoma: assessment of mutational and indirect activation. (18784923)Raepple D.... Scheele J.S.2009RASA1
8Human T cell leukemia virus reactivation with progres sion of adult T-cell leukemia-lymphoma. (19204798)Ratner L.... Lairmore M.2009IFNA2
9Preliminary study on leukemia related gene zo-1 invo lved in pathogenesis of leukemia]. (19840438)Dou L.P.... Yu L.2009TJP1
10Mature B-cell lymphoblastic leukemia with MLL rearrangement: an uncommon and distinct subset of childhood acute leukemia. (18007578)Blin N.... Avet-Loiseau H.2008MLL
11CCAAT/enhancer binding protein-alpha polymorphisms occur more frequently than mutations in acute myeloid leukemia and exist across all cytogenetic risk groups and leukemia subtypes. (18729193)Leecharendkeat A.... Auewarakul C.U.2008CEBPA
12Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia. (18677410)Chiang M.Y.... Pear W.S.2008NOTCH1
13Hematopoietic stem cells and progenitors of chronic myeloid leukemia express leukemia-associated antigens: implications for the graft-versus-leukemia effect and peptide vaccine-based immunotherapy. (18548092)Yong A.S.... Barrett A.J.2008WT1, PRTN3, PRAME
14Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group. (17252021)Thomas X.... Dombret H.2007CSF2
15Deficient expression of NCR in NK cells from acute myeloid leukemia: Evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction. (16940427)Fauriat C.... Costello R.T.2007NCR2, NCR1, NCR3
16Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide synthesis and inhibition of glucosylceramide synthase activity. (17550847)Dbaibo G.S.... Bazarbachi A.2007UGCG
17Acute myeloid leukemia with T-cell receptor gamma gene rearrangement occurring in a patient with chronic lymphocytic leukemia: a case report. (16947317)Hatoum H.A.... Shamseddine A.I.2007TRG@
18Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias. (17597811)Mullighan C.G.... Downing J.R.2007MLL, NPM1, MEIS1
19Precursor T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma and acute biphenotypic leukemias. (17369128)Han X.... Bueso-Ramos C.E.2007NOTCH1, TLX1
20Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia. (17673900)Savani B.N.... Barrett A.J.2007KIR3DL1
21MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia. (16307022)Stam R.W.... Pieters R.2006MLL
22Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study. (16921041)Paschka P.... Bloomfield C.D.2006KIT
23Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. (17097559)Deshpande A.J.... Buske C.2006PICALM
24Congenital MLL-positive B-cell acute lymphoblastic leukemia (B-ALL) switched lineage at relapse to acute myelocytic leukemia (AML) with persistent t(4;11) and t(1;6) translocations and JH gene rearrangement. (16085566)Jiang J.G.... Alobeid B.2005MLL
25Treatment with granulocyte colony-stimulating factor after allogeneic bone marrow transplantation for acute leukemia increases the risk of graft-versus-host disease and death: a study from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation. (14691124)RingdAcn O.... Frassoni F.2004CSF3
26Clonal variation of the immunogenotype in relapsed ETV6/RUNX1-positive acute lymphoblastic leukemia indicates subclone formation during early stages of leukemia development. (14695996)Peham M.... Panzer-GrA1mayer E.R.2004ETV6
27Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. (12717436)Tartaglia M.... Gelb B.D.2003PTPN11
28Is B-lineage acute lymphoblastic leukemia with a mature phenotype and l1 morphology a precursor B-lymphoblastic leukemia/lymphoma or Burkitt leukemia/lymphoma? (14521459)Li S.... Lew G.2003MYC
29Oncoviral bovine leukemia virus G4 and human T-cell leukemia virus type 1 p13(II) accessory proteins interact with farnesyl pyrophosphate synthetase. (11773414)Lefebvre L.... Willems L.2002FDPS, C6orf47
30Adhesion molecule expression in CD5-negative/CD10-negative chronic B-cell leukemias: comparison with non-Hodgkin's lymphomas and CD5-positive B-cell chronic lymphocytic leukemia. (11172297)Finn W.G.... Stoolman L.M.2001ITGB7
31Leukemia blast-induced T-cell anergy demonstrated by leukemia-derived dendritic cells in acute myelogenous leukemia. (11378266)Narita M.... Aizawa Y.2001TNF, IL4, CSF2
32PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells. (11301322)Moog-Lutz C.... Koretzky G.2001LYN, LCP2, SKAP2
33Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage- colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses. (10942373)Stripecke R.... Kohn D.B.2000CSF2
34Deregulated expression of promyelocytic leukemia zinc finger protein in B-cell chronic lymphocytic leukemias does not affect cyclin A expression. (11920165)Parrado A.... Padua R.A.2000CCNA2, ZBTB16
35Participation of granulocyte colony-stimulating factor in the growth regulation of leukemia cells from Philadelphia chromosome-positive acute leukemia and blast crisis of chronic myeloid leukemia. (10942233)Inukai T.... Nakazawa S.2000CSF3, CSF3R
36Improvement of extrathymic T cell type of large granular lymphocyte (LGL) leukemia by cyclosporin A: the serum level of Fas ligand is a marker of LGL leukemia activity. (11073168)Saitoh T.... Murakami H.2000FASLG, THPO
37The relationship between the expression of transferrin receptors (TfR) on leukemia cells and the cell proliferation and iron metabolism status in childhood acute leukemias (11601239)Huang G.... Luo C.1999TFRC
38Regulation of c-fos gene transcription and myeloid cell differentiation by acute myeloid leukemia 1 and acute myeloid leukemia-MTG8, a chimeric leukemogenic derivative of acute myeloid leukemia 1. (10100620)Hwang E.S.... Lee S.K.1999MKL1
39Cytokine expression and tumorigenicity of large granular lymphocytic leukemia cells from mice transgenic for the tax gene of human T-cell leukemia virus type I. (9226179)Grossman W.J.... Ratner L.1997CNTN2
40Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study. (9164186)Slack J.L.... Bloomfield C.D.1997PML
41High levels of AP-2-binding activity in cell lines infected with human T-cell leukemia virus type I: possible enhancement of AP-2 binding by human T-cell leukemia virus type I tax. (8631013)Mori N.... Prager D.1996TFAP2A
42Induction of ICAM-1 and LFA-3 by Tax1 of human T-cell leukemia virus type 1 and mechanism of down-regulation of ICAM-1 or LFA-1 in adult-T-cell-leukemia cell lines. (7530239)Tanaka Y.... Yoshie O.1995ICAM1, ITGAL
43Natural killer cell acute leukemia with myeloid antigen expression. A previously undescribed form of acute leukemia. (7639197)Dunphy C.H.... Rodriguez G.1995DNTT
44EVI1 expression associated with a 3q26 anomaly in a leukemia cell line derived from the blast crisis of chronic myeloid leukemia. (7808006)Ohyashiki K.... Toyama K.1994GATA1, GATA2, MECOM
45HLA-DR-, CD33+, CD56+, CD16- myeloid/natural killer c ell acute leukemia: a previously unrecognized form of acute leukemia potentiall y misdiagnosed as French-American-British acute myeloid leukemia-M3. (7517211)Scott A.A.... Licht J.D.1994RARA, MPO
46Problems concerned with adult T-cell leukemia. 1) Causes of death and early diagnosis of cytomegalovirus pneumonia in adult T-cell leukemia. 2) Clinicopathological features of CD30 positive adult T-cell leukemia (7869589)Kikuchi H.... Yokoyama S.1994TNFRSF8
47Differences between blastic chronic myeloid leukemia and Ph-positive acute leukemia. (8251902)Berger R.1993BCR
48Interleukin-2 increases production and secretion of parathyroid hormone-related peptide by human T cell leukemia virus type I-infected T cells: possible role in hypercalcemia associated with adult T cell leukemia. (8099324)Ikeda K.... Matsumoto T.1993IL2, PTHLH
49Expression of MDR1 gene in acute leukemia cells: association with CD7+ acute myeloblastic leukemia/acute lymphoblastic leukemia. (7694687)Miwa H.... Shirakawa S.1993ABCB1
50Purine metabolism enzymes and immunological phenotype in chronic B-cell malignancies: chronic lymphocytic leukemia, prolymphocytic leukemia and hairy cell leukemia. (2125699)BabusA-kovA! O.... UjhA!zy P.1990ADA

Expression for genes affiliated with Leukemia

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Leukemia

Pathways for genes affiliated with Leukemia

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36QIAGEN, 20KEGG, 3Cell Signaling Technology, 37R&D Systems, 10EMD Millipore, 41Thomson Reuters, 34PharmGKB
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Pathways related to leukemia according to GeneDecks:

(show top 50)    (show all 416)
idPathwayScoreTop Affiliating Genes
1MAPK Signaling3658.6PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, SEMA3A
2Akt Signaling3652.6PIK3R3, PIK3R1, PIK3CG, PDE3B, KIT, BTK
3Transendothelial Migration of Leukocytes3639.3PIK3R3, PIK3R2, PIK3R1, NCF2, NCF4, WASF1
4NF-KappaB (p50-p65) Pathway3635.1PIK3R3, PIK3R2, PIK3R1, RELA, KITLG, BTRC
5Activation of PKC through GPCR3635.0PIK3R3, PIK3R2, PIK3R1, PDE1A, PDE3B, KIT
6Natural killer cell mediated cytotoxicity2034.2PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
7eNOS Signaling3633.9PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, SEMA3A
8Apoptosis and Autophagy333.8PIM2, PIR, PIM1, PDCD4, PDCD6IP, SERPINB5
9Jak-STAT signaling pathway2033.8PIK3CB, PIK3CD, PIAS2, PIK3CA, PIK3R3, PIK3R2
10PPAR Pathway3633.3PIK3R3, PIK3R1, NCOA1, KIT, KITLG, SEMA3A
11mTOR Pathway3632.9PIK3R3, PIK3R2, PIK3R1, KITLG, SEMA3A, VEGFC
12JNK Pathway3632.8PIK3R1, KIT, KITLG, BTK, BMP2, BMP4
13Nuclear Receptor Activation by Vitamin-A3630.6NCOA1, NCOA3, KIT, KITLG, SEMA3A, VEGFC
14CDC42 Pathway3629.9KIT, VAV1, RAF1, RALA, LIFR, PARD6A
15TGF-beta Signaling Pathways3729.9PIK3CB, PIK3CD, PIK3R2, PIK3R1, PIK3CG, NCOR1
16WNT Signaling3629.7LRP5, LRP6, BTRC, VIM, MYC, RAC1
17Apoptotic Pathways in Synovial Fibroblasts3629.5PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, SEMA3A
18Tyrosine Kinases / Adaptors328.3SH2D1A, KIT, KITLG, BTK, VEGFC, BMX
19TRAF Pathway3626.1PIK3R3, PIK3R2, PIK3R1, MYD88, BIRC2, BIRC3
20Actin Nucleation and Branching3624.4KIT, RAC3, RAC1, RAC2, LIFR, KDR
21Development Prolactin receptor signaling1023.0PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, RELA
22NFAT Signaling and Lymphocyte Interactions3622.9BTK, BMP2, BMP4, BMP6, BCL2, BAX
23Development_Thrombopoietin-regulated cell processes4121.7PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
24TNF Signaling3621.5BID, BIRC2, BIRC3, CHUK, BAG4, ATF3
25Prolactin Signaling3621.4PIK3R3, PIK3R2, BRAF, MYC, RAF1, CEBPB
26ICos-ICosL Pathway in T-Helper Cell3621.3PIK3R3, PIK3R1, PIK3C2A, VAV1, RAC1, CHUK
27Immune response IL-1 signaling pathway1021.0RELA, SERPINE1, MYD88, CHUK, UBB, UBE2N
28Development_A3 receptor signaling4120.4PIK3R5, PIK3CG, REL, RELA, RELB, MYC
29Translation _Regulation of EIF4F activity4120.3PIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, RAC1
30Immune response_IL-9 signaling pathway4120.3PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
31VEGF Signaling Pathway3420.3PIK3C2A, VEGFA, VEGFC, RAF1, KDR, ITGAV
32Transcription Role of VDR in regulation of genes involved in osteoporosis1020.2VDR, BGLAP, CGA, JUN, CDX2, CDKN1C
33Development_PDGF signaling via STATs and NF-kB4119.9PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
34Development_Flt3 signaling4119.8PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, VAV1
35Fas Signaling3619.8BTK, RB1, LMNA, LMNB1, RAF1, BID
36ErbB Family Pathway3619.7PIK3R3, PIK3R2, PIK3R1, BRAF, RAF1, JUN
37Immune response_CD16 signaling in NK cells4119.7PIK3CD, PIK3R3, PIK3R2, PIK3R1, VAV1, ZAP70
38Apoptotic Pathways Triggered By HIV13619.7BID, BIRC2, BIRC3, BCL2, BCL2L1, CHUK
39HMGB1 Pathway3619.6PIK3R3, PIK3R2, PIK3R1, RAC1, JUN, CDC42
40Apoptosis and survival Lymphotoxin-beta receptor signaling1019.5RELA, RELB, VCAM1, BIRC2, CHUK, BAX
41Transcription_Role of VDR in regulation of genes involved in osteoporosis4118.9VDR, BGLAP, CGA, JUN, CDX2, CDKN1C
42Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway1018.8REL, RELA, RELB, BCL2, BCL2A1, BCL2L1
43Colorectal cancer2018.6PIK3CB, PIK3CD, PIK3R3, PIK3R2, PIK3R1, PIK3R5
44Development_Glucocorticoid receptor signaling4118.5NCOA1, NCOA2, REL, RELA, RELB, SERPINE1
45Cell adhesion PLAU signaling1018.2PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
46Transcription PPAR Pathway1017.8PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, NCOA1
47Immune response IFN gamma signaling pathway1015.9PIK3R3, RAP1A, RAPGEF1, ATF2, JAK2, MCM5
48Development EGFR signaling pathway1011.4CBL, DUSP4
49Wnt signaling pathway20INFLRP5, LRP6, SFRP1, SFRP2, SFRP4, SFRP5
50Pathways in cancer20INFPIK3CB, PIK3CD, PIAS2, PIK3CA, PIK3R3, PIK3R2

Compounds for genes affiliated with Leukemia

about this section
Sources:
32Novoseek , 34PharmGKB, 9DrugBank, 18HMDB, 42Tocris Bioscience
See all sources

Compounds related to leukemia according to GeneDecks:

(show top 50)    (show all 421)
idCompoundScoreTop Affiliating Genes
1estrogen32 INFZNF673, PIK3CB, PIK3R1, PIAS1, LRP5, COG2
2ethanol32 34 9 18 9 INFNCAM1, KITLG, RBP1, BPI, RARB, BLVRB
3cocaine32 9 9 INFPIK3C2A, PDE4A, CNR1, CNTF, SELE, SELP
4cisplatin32 34 9 9 90.8PIK3CA, PIK3C2A, REV1, REV3L, CNR2, KITLG
5doxorubicin32 34 9 9 69.4PIK3CA, PIK3C2A, PIK3CG, NCAM1, RECK, KIT
6etoposide32 42 9 9 52.4PIK3CB, PIK3CA, PIK3R1, PIK3CG, RECK, CNTN2
7retinoid32 46.8NCOA1, NCOA2, NCOA3, NCOR1, NCOR2, CNTN2
8ly29400232 46.0PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, VTN
9chloramphenicol32 9 9 44.5KLF9, REL, CNTN2, GC, SELE, SERPINC1
10folate32 37.8RECK, VWF, RBP4, SELE, SERPINC1, SERPINA3
11quercetin32 42 9 18 9 40.4PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
12cytochalasin d32 42 35.3PIK3CG, KITLG, VWF, VTN, SELE, SELL
13azathioprine32 34 9 9 32.9PCNA, VIM, MYOD1, BMP2, BMP4, RARB
141,25 dihydroxy vitamin d332 29.8LRP5, NCOA1, GC, RB1, VDR, MYC
15homocysteine32 18 28.3PIK3C2A, COG2, VWF, SELE, SELP, SERPINC1
16celecoxib32 42 34 9 18 9 31.8PIK3R1, PIK3CG, REN, PCNA, VEGFA, BIRC5
17ag 147832 26.6PIK3CA, PIK3CG, SERPINE1, RAF1, BAK1, JUN
18gefitinib32 34 9 9 28.8PIK3CA, PIK3CG, KIT, SFTPD, SELP, VIM
19neomycin32 23.4KITLG, VIM, BMP2, CDKN2A, GUSB, FGF4
20phenobarbital32 9 9 24.4PCNA, LPL, MYC, KCNH2, UGT1A1, FOXM1
21ribavirin32 34 9 9 25.2LEP, MX1, LBR, CD81, CD40LG, ITPA
22infliximab32 9 9 24.2SELE, VEGFA, BGLAP, BAK1, LBR, ITGA4
23vincristine32 34 9 9 24.6NCAM1, RECK, KIT, BTK, MYCN, BCL6
24sialic acid32 21.4NCAM1, RECK, GCNT1, RBP4, SELL, SELPLG
25leptomycin b32 21.3CNTN2, BRCA1, LPP, RANBP1, RAN, BIRC5
26depsipeptide32 21.2KITLG, RB1, SERPINB5, BRAF, MYC, RAF1
274-hydroxytamoxifen32 19.9NCOA1, NCOA2, NCOA3, NCOR1, NCOR2, SERPINB9
28ganciclovir32 9 9 21.6KITLG, VIM, BMP6, KDR, LEP, CEACAM3
29roscovitine32 19.0PIK3CG, PCNA, VIM, BIRC5, PARP1, BCL2L1
30ndga32 17.9VCAM1, JUN, MMP13, MMP3, FPR1, FOS
31sulfasalazine32 9 9 19.6SELE, NAT2, CHUK, MTHFR, MPO, CD79A
32budesonide32 42 9 9 17.8PDE4A, KITLG, SFTPD, BGLAP, CD36, IL5RA
33glycerol32 9 18 9 INFPIK3C2A, PDE4A, VWF, PC, PCNA, SERPINC1
34indomethacin32 9 9 INFNCOA1, PDE4A, REN, CNR1, PCNA, SELL
35dextran sulfate32 INFVTN, SELE, SELL, SELP, SERPINC1, LPL
36morphine32 9 9 INFCNR1, VIP, UGT1A1, YY1, JUNB, CDK5
37magnesium32 9 18 9 INFPIK3C2A, PDE4A, PC, GC, RBP4, BPI
38mg 13232 42 INFPIK3CG, NCOA2, NCOR2, PCNA, BRCA1, VDR
39tacrolimus32 34 9 9 INFPIK3CA, PIN1, REL, REN, VTN, RCAN1
40cyclosporin a32 42 INFPIK3CA, PIK3C2A, PIK3CG, PIN1, COG2, PDE4A
41serine32 INFPIK3CB, PIK3CD, PIM2, PIK3CA, PIK3R1, PIAS1
42sorafenib32 9 9 INFKIT, BRAF, VHL, VEGFA, RAF1, BIRC3
43phospholipid32 INFPIK3R1, COG2, PDE4A, VWF, SFTPD, RBP4
44butyrate32 INFKLF4, NCF2, NCOA1, NCOA3, KITLG, PCNA
45creatinine32 INFNCAM1, REN, KITLG, VWF, PCNA, GC
46guanidine hydrochloride32 INFCNTF, VWF, SERPINA3, VNN1, LPL, VDAC1
47choline32 9 18 9 INFPIK3C2A, CNTF, CNTN2, VIM, VIP, MYB
48phosphatidylcholine32 INFPIK3CB, CNR1, SFTPD, SELE, VIM, VIP
49phenylalanine32 INFPIK3R1, BTD, BTK, SELPLG, VAV1, RAB6A
50asparagine32 INFPDE4A, RECK, SERPINF2, NAT2, LMAN1, RAP1A

GO Terms for genes affiliated with Leukemia

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Sources:
12Gene Ontology
See all sources

Cellular components related to leukemia according to GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1integral to plasma membraneGO:005887INFLRP1, NCKAP1L, NCR1, NCR2, NCR3, SGCE
2perinuclear region of cytoplasmGO:048471INFPICALM, PDE4A, PDE4B, BUB1B, GC, SELE
3nucleoplasmGO:005654INFPIAS1, PIN1, WDHD1, RFC1, RFWD2, NCOA1
4plasma membraneGO:005886INFZNF22, PIK3CD, PIK3R1, PIK3C2A, PIK3CG, PIGU
5nucleusGO:005634INFZNF282, ZNF22, ZNF382, ZNF268, ZNF76, ZNF124
6cytosolGO:005829INFPIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
7nucleolusGO:005730INFZNF22, ZNF384, PIAS4, PINX1, WDHD1, SH3D19
8extracellular spaceGO:00561577.5REN, CNTF, KIT, KITLG, VTN, SFN
9membraneGO:01602048.7PIK3R5, PIK3CG, PI4K2B, NCF4, NCKAP1L, PDE3B
10cell surfaceGO:00998638.3LRP6, LRPAP1, NCAM1, CNTN2, CNTNAP2, SFRP1
11external side of plasma membraneGO:00989734.5NCAM1, KIT, VWF, BTLA, SELL, SELP
12transcription factor complexGO:00566725.8KLF4, RELA, RBL2, LMO2, LMO4, MYOD1
13protein complexGO:04323425.7SET, BRCA1, BRCA2, VCL, MYC, BMP2
14PML bodyGO:01660518.9PIAS2, PIAS4, RDM1, RB1, N4BP1, RAD51
15extracellular regionGO:005576INFLRPAP1, NCAM1, PDCD1LG2, KIAA0100, KITLG, KIR3DP1
16cytoplasmGO:005737INFPIR, PIAS4, PIK3R5, PIK3C2A, PIK3CG, PIN1
17membrane raftGO:045121INFBTK, SELE, BSG, BST2, BCL10, UMOD

Biological processes related to leukemia according to GeneDecks:

(show top 50)    (show all 91)
idNameGO IDScoreTop Affiliating Genes
1inflammatory responseGO:006954INFPIK3CD, PIK3CG, NCR3, RELA, CNR2, KIT
2positive regulation of transcription from RNA polymerase II promoterGO:04594470.7PIAS2, LRP5, LRP6, KLF2, KLF4, KLF6
3positive regulation of transcription, DNA-dependentGO:04589354.5PIM2, PIAS2, PIAS1, PICALM, LRP5, LRP6
4immune responseGO:00695551.8RFX1, NCF4, NCR3, PDCD1LG2, CNR2, KIR2DS5
5negative regulation of cell proliferationGO:00828546.0PIM2, PINX1, KLF10, KLF4, KIFAP3, SFN
6cell proliferationGO:00828339.7PIM2, PIM1, KLF10, KITLG, SFN, PCNA
7cell adhesionGO:00715536.6NCAM1, CNTN2, CNTNAP1, CNTNAP2, KITLG, VWF
8nerve growth factor receptor signaling pathwayGO:04801133.5PIK3CB, PIK3CA, PIK3R2, PIK3R1, SH3GL2, PDE1A
9angiogenesisGO:00152529.0PIK3CA, PIK3CG, KLF5, NCL, PDCD10, PDE3B
10response to hypoxiaGO:00166627.9VEGFA, VCAM1, BNIP3, MYOCD, BMP2, RAF1
11transcription initiation from RNA polymerase II promoterGO:00636726.4NCOR1, NCOR2, RBPJ, RBL1, SERPINE1, VDR
12insulin receptor signaling pathwayGO:00828626.3PIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3C2A
13epidermal growth factor receptor signaling pathwayGO:00717325.7PIK3CA, PIK3R1, PIK3C2A, SH3GL2, PDE1A, RAF1
14protein autophosphorylationGO:04677725.4PIM1, KIT, MYLK2, BMX, KDR, ULK3
15in utero embryonic developmentGO:00170124.8KLF1, KLF2, PCGF2, PCNT, BMP2, RARRES2
16positive regulation of NF-kappaB transcription factor activityGO:05109224.6RELA, BTK, MYD88, RAB7B, BCL10, CHUK
17cell cycle arrestGO:00705024.5BTG4, RB1, RBM38, NBN, MYC, RASSF1
18Toll signaling pathwayGO:00806323.7RELA, BTK, MYD88, CHUK, UBB, UBC
19positive regulation of gene expressionGO:01062823.5NCOA3, RELB, KIT, SFRP4, BRAF, VEGFA
20toll-like receptor 4 signaling pathwayGO:03414223.5RELA, BTK, MYD88, CHUK, UBB, UBC
21toll-like receptor signaling pathwayGO:00222423.3RELA, BTK, MYD88, BCL10, CHUK, UBB
22response to organic cyclic compoundGO:01407023.2NCF2, SFRP1, BTG2, SELP, BMP4, LEF1
23transforming growth factor beta receptor signaling pathwayGO:00717922.9KLF10, NCOR1, NCOR2, RBL1, SERPINE1, MYC
24MyD88-dependent toll-like receptor signaling pathwayGO:00275522.7RELA, BTK, MYD88, CHUK, UBB, UBC
25induction of apoptosis by extracellular signalsGO:00862422.6BTK, VDR, VAV1, VAV3, RASGRF1, RAC1
26toll-like receptor 2 signaling pathwayGO:03413422.3RELA, BTK, MYD88, CHUK, UBB, UBC
27toll-like receptor 1 signaling pathwayGO:03413022.2RELA, BTK, MYD88, CHUK, UBB, UBC
28toll-like receptor 3 signaling pathwayGO:03413821.9RELA, CHUK, UBB, UBC, ATF1, ATF2
29TRIF-dependent toll-like receptor signaling pathwayGO:03566621.8RELA, CHUK, UBB, UBC, ATF1, ATF2
30response to estradiol stimulusGO:03235521.8NCOA1, SFRP4, GC, BRCA2, VDR, BMP4
31T cell costimulationGO:03129521.7PIK3CA, PIK3R3, PIK3R2, PIK3R1, PDCD1, PDCD1LG2
32MyD88-independent toll-like receptor signaling pathwayGO:00275621.1RELA, CHUK, UBB, UBC, ATF1, ATF2
33positive regulation of ERK1 and ERK2 cascadeGO:07037420.9SERPINF2, BRAF, BMP2, BMP4, KDR, CD74
34response to ethanolGO:04547120.8CNR1, RBP4, BGLAP, BCL2, LCT, BAK1
35interferon-gamma-mediated signaling pathwayGO:06033320.0PIAS1, NCAM1, VCAM1, MT2A, B2M, JAK1
36cellular response to mechanical stimulusGO:07126018.8BNIP3, MYD88, BCL10, CHEK1, BAD, BAK1
37positive regulation of phosphatidylinositol 3-kinase cascadeGO:01406818.4CNTF, KIT, SELP, SEMA4D, KDR, JAK2
38chemotaxisGO:006935INFPIK3CB, RALA, CMTM5, S100A9, FPR1, FOSL1
39negative regulation of transcription, DNA-dependentGO:045892INFZNF282, ZNF382, PIAS4, KLF4, PDCD4, RELA
40cell surface receptor signaling pathwayGO:007166INFBSG, BRD8, MYD88, LIFR, LILRB2, BIRC2
41fibroblast growth factor receptor signaling pathwayGO:008543INFPIK3CA, PIK3R1, PDE1A, BRAF, RAF1, CHUK
42DNA repairGO:006281INFRFC1, REV1, RDM1, PCNA, BTG2,
43signal transductionGO:007165INFPIK3CB, PIK3CD, SH3BP2, SH3GL1, SH3GL2, SH3GL3
44positive regulation of cell proliferationGO:008284INFLRP5, KLF5, PDCD10, CNTF, CNTFR, KIT
45transcription, DNA-dependentGO:006351INFZNF282, ZNF22, ZNF382, ZNF268, ZNF76, ZNF124
46response to lipopolysaccharideGO:032496INFNCF2, CNR1, CNR2, SELE, SELP, UGT1A1
47positive regulation of cell migrationGO:030335INFSEMA4D, VEGFA, MYO1F, BMP2, KDR, LEF1
48innate immune responseGO:045087INFPIK3CD, PIK3CG, PIN1, NCF2, RELA, SFTPD
49small molecule metabolic processGO:044281INFPIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
50response to drugGO:042493INFNCF2, NCKAP1L, PDE4A, REN, SFRP1, SFRP2

Molecular functions related to leukemia according to GeneDecks:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1protein homodimerization activityGO:042803INFLRP6, PDCD10, KIT, VWF, SERPINF2, BST2
2ATP bindingGO:00552480.8PIK3CB, PIK3CD, PIM2, PIK3CA, PIK3C2A, PIK3CG
3DNA bindingGO:00367775.6ZNF282, ZNF22, ZNF382, ZNF268, ZNF76, ZNF124
4sequence-specific DNA bindingGO:04356550.4KLF2, RERE, VENTX, VDR, LMX1A, MYC
5receptor bindingGO:00510233.0LRP6, REN, CNTFR, CNTNAP1, CNTNAP2, SELPLG
6protein heterodimerization activityGO:04698232.0BRAF, VEGFA, BOK, BNIP3, MYC, MYOD1
7enzyme bindingGO:01989931.4PIAS1, NCOA1, CNTNAP2, PCBP2, BTG1, BRCA1
8chromatin bindingGO:00368230.8NCOA1, NCOA2, NCOA3, RELA, PCGF2, BRD2
9cytokine activityGO:00512528.0CNTF, KITLG, SECTM1, VEGFA, BMP2, BMP4
10transcription regulatory region DNA bindingGO:04421227.8KLF1, KLF4, NCOR1, RELA, RBBP5, BRCA1
11growth factor activityGO:00808326.6CNTF, KITLG, VEGFA, VEGFC, BMP2, BMP4
12transcription coactivator activityGO:00371326.1PIAS2, PIAS1, NCOA1, NCOA2, NCOA3, RB1
13double-stranded DNA bindingGO:00369020.8KLF4, KLF6, MYC, RAD51, USF1, PAX4
14sequence-specific DNA binding transcription factor activityGO:003700INFZNF268, KLF1, KLF10, KLF2, KLF3, KLF4
15transcription factor bindingGO:008134INFPIM1, RELA, RB1, RBL1, NBN, NAB2
16protein tyrosine kinase activityGO:004713INFKIT, BTK, BMX, BLK, KDR, BCR
17receptor activityGO:004872INFLRP1, CNTNAP1, KIR2DL1, KIR2DL3, BTLA, SEMA3A
18identical protein bindingGO:042802INFSH3GL2, SH3GL3, RELA, CNTN2, SFRP1, PCNA
19protein kinase bindingGO:019901INFRELA, VIM, USF1, PARK2, BCL10, BCL2L1
20signal transducer activityGO:004871INFSH2B3, NCOA1, NCOA2, NCOA3, PDCD1, SECTM1
21protein bindingGO:005515INFPIK3CB, PIGA, PIK3CD, PIAS2, PIK3CA, PIK3R2
22transcription corepressor activityGO:003714INFPIAS1, NCOR1, NCOR2, RELB, SF1, NAB2
23ubiquitin protein ligase bindingGO:031625INFPIAS2, PIAS4, RELA, PCBP2, RB1,

Sources for Leukemia

about this section
2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS
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