JMML
MCID: LKM066
MIFTS: 60

Leukemia, Acute Myelomonocytic, Somatic, Somatic (JMML) malady

Categories: Genetic diseases, Rare diseases, Cancer diseases, Blood diseases, Immune diseases

Aliases & Classifications for Leukemia, Acute Myelomonocytic, Somatic, Somatic

About this section
Sources:
11Disease Ontology, 12diseasecard, 13DISEASES, 27GTR, 30ICD10, 31ICD10 via Orphanet, 35LifeMap Discovery®, 37MedGen, 39MeSH, 40MESH via Orphanet, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 52OMIM, 54Orphanet, 62SNOMED-CT, 64The Human Phenotype Ontology, 68UMLS, 69UMLS via Orphanet, 70UniProtKB/Swiss-Prot
See all MalaCards sources

Aliases & Descriptions for Leukemia, Acute Myelomonocytic, Somatic, Somatic:

Name: Leukemia, Acute Myelomonocytic, Somatic, Somatic 52 35
Juvenile Myelomonocytic Leukemia 52 35 11 48 54 27 50 13 68
Leukemia, Juvenile Myelomonocytic 52 48 70 12
Jmml 48 54 70
 
Leukemia, Juvenile Myelomonocytic, Somatic 52
Juvenile Chronic Myelomonocytic Leukemia 54
Juvenile Chronic Myelogenous Leukemia 70
Leukemia, Myelomonocytic, Juvenile 39

Characteristics:

Orphanet epidemiological data:

54
juvenile myelomonocytic leukemia:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe); Age of onset: Childhood,Infancy

HPO:

64
leukemia, acute myelomonocytic, somatic, somatic:
Inheritance: somatic mutation

Classifications:



External Ids:

OMIM52 607785
Disease Ontology11 DOID:0050458
ICD1030 C93.3, C93.30
MeSH39 D054429
NCIt45 C9233
Orphanet54 ORPHA86834
MESH via Orphanet40 D054429
UMLS via Orphanet69 C0349639
ICD10 via Orphanet31 C93.3

Summaries for Leukemia, Acute Myelomonocytic, Somatic, Somatic

About this section
OMIM:52 Juvenile myelomonocytic leukemia is an aggressive pediatric myelodysplastic syndrome (MDS)/myeloproliferative disorder... (607785) more...

MalaCards based summary: Leukemia, Acute Myelomonocytic, Somatic, Somatic, also known as juvenile myelomonocytic leukemia, is related to noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia and juvenile myelomonocytic leukemia, somatic arhgap26-related, and has symptoms including exanthema, exanthema and fatigue. An important gene associated with Leukemia, Acute Myelomonocytic, Somatic, Somatic is PTPN11 (Protein Tyrosine Phosphatase, Non-Receptor Type 11), and among its related pathways are Signaling events mediated by VEGFR1 and VEGFR2 and Insulin Pathway. Affiliated tissues include lymph node, and related mouse phenotypes are Increased cell migration and Decreased cell migration.

UniProtKB/Swiss-Prot:70 Leukemia, juvenile myelomonocytic: An aggressive pediatric myelodysplastic syndrome/myeloproliferative disorder characterized by malignant transformation in the hematopoietic stem cell compartment with proliferation of differentiated progeny. Patients have splenomegaly, enlarged lymph nodes, rashes, and hemorrhages.

Related Diseases for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Diseases related to Leukemia, Acute Myelomonocytic, Somatic, Somatic via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 57)
idRelated DiseaseScoreTop Affiliating Genes
1noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia12.5
2juvenile myelomonocytic leukemia, somatic arhgap26-related12.1
3juvenile myelomonocytic leukemia, somatic cbl-related12.1
4juvenile myelomonocytic leukemia, somatic nf1-related12.1
5juvenile myelomonocytic leukemia, somatic ptpn11-related12.1
6noonan syndrome 111.2
7noonan syndrome 611.1
8noonan syndrome 811.1
9noonan syndrome 411.1
10noonan syndrome 511.1
11noonan syndrome 711.1
12noonan syndrome 311.1
13noonan syndrome 911.1
14noonan syndrome 1011.1
15myelodysplastic myeloproliferative cancer11.1
16pseudomonas stutzeri infections10.3KRAS, NRAS, PTPN11
17rdh12-related leber congenital amaurosis10.3KRAS, NRAS, PTPN11
18erythrocyte lactate transporter defect10.3HRAS, KRAS, NRAS
19melanocytic nevus syndrome, congenital, somatic10.3HRAS, KRAS, NRAS
20syndactyly-polydactyly-earlobe syndrome10.2HRAS, KRAS, NF1, PTPN11
21leukemia10.2
22kidney clear cell sarcoma10.2HRAS, KRAS, PDGFRA
23hyperproinsulinemia10.2HRAS, KRAS, PTPN11
24ossifying fibromyxoid tumor10.2HRAS, KRAS, NRAS
25cardiomyopathy, dilated, 1r10.2NF1, PTPN11, SPRED1
26skin epithelioid hemangioma10.2HRAS, NF1, PTPN11
27abdominal obesity-metabolic syndrome10.2PDGFRA, RUNX1, SETBP1
28malignant skin fibrous histiocytoma10.2HRAS, KRAS
29regional odontodysplasia10.2GATA2, SETBP1, TET2
30spongiotic dermatitis10.2HRAS, KRAS, NRAS
31unilateral hemispheric polymicrogyria10.2FLT3, RUNX1
32agammaglobulinemia 8, autosomal dominant10.2FLT3, GATA2, KRAS
33colorectal adenoma10.2FLT3, RUNX1, SETBP1, TET2
34glomeruloid hemangioma10.2HRAS, KRAS, NF1, NRAS, PTPN11
35cerebellar hypoplasia and mental retardation with or without quadrupedal locomotion 110.2CBL, DPM1, STAT5B
36vascular hemostatic disease10.2HRAS, KRAS, PDGFRA
37focal epilepsy10.1PDGFRA, PTPN11, STAT5B, TET2
38myeloid and lymphoid neoplasms associated with fgfr1 abnormalities10.1DPM1, PDGFRA
39erythrocytosis, somatic10.1DPM1, FLT3, PDGFRA, TET2
40seborrheic dermatitis10.1HRAS, NF1, PDGFRA, PTPN11, SPRED1
41chromosome 15q11-q13 duplication syndrome10.1HRAS, NF1, PTPN11, SHOC2, SPRED1
42leopard syndrome 310.1HRAS, KRAS, PTPN11, SHOC2, SPRED1
43familial hyperaldosteronism10.1CBL, FLT3, HRAS, KRAS, NRAS, RUNX1
44liver disease10.1CSF2, FLT3, MLLT11, NRAS, PTPN11, RUNX1
45neurotrophic keratoconjunctivitis10.1CSF2, CSF2RA, GATA2
46hyperparathyroidism, neonatal10.0CSF2, FLT3, GATA2, NRAS, TET2
47bleeding disorder, platelet-type, 1810.0FLT3, GATA2, NRAS, RUNX1, STAT5B
48hyperphosphatasia with mental retardation syndrome 210.0FLT3, PDGFRA, RUNX1
49milker's nodule10.0CBL, FLT3, HRAS, NRAS, PTPN11, RUNX1
50metachondromatosis10.0HRAS, KRAS, NF1, NRAS, PTPN11, SHOC2

Graphical network of the top 20 diseases related to Leukemia, Acute Myelomonocytic, Somatic, Somatic:



Diseases related to leukemia, acute myelomonocytic, somatic, somatic

Symptoms & Phenotypes for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Clinical features from OMIM:

607785

Human phenotypes related to Leukemia, Acute Myelomonocytic, Somatic, Somatic:

 64
id Description HPO Frequency HPO Source Accession
1 juvenile myelomonocytic leukemia64 HP:0012209

UMLS symptoms related to Leukemia, Acute Myelomonocytic, Somatic, Somatic:


exanthema, fatigue, fever

GenomeRNAi Phenotypes related to Leukemia, Acute Myelomonocytic, Somatic, Somatic according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00055-A-310.2CBL, HRAS, KRAS, NF1
2GR00055-A-110.0ARHGAP26, CBL, HRAS, KRAS, NF1
3GR00381-A-19.7FLT3, HRAS, KRAS, NF1, NRAS, PDGFRA

MGI Mouse Phenotypes related to Leukemia, Acute Myelomonocytic, Somatic, Somatic according to GeneCards Suite gene sharing:

41 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.9CBL, KRAS, NF1, NRAS, PDGFRA, PTPN11
2MP:00053719.5CBL, KRAS, NF1, NRAS, PDGFRA, PTPN11
3MP:00053829.3CBL, CSF2, HRAS, KRAS, NF1, NRAS
4MP:00053909.1CBL, CSF2, FLT3, HRAS, KRAS, NF1
5MP:00053809.0CSF2, GATA2, KRAS, NF1, NRAS, PDGFRA
6MP:00020069.0CSF2, FLT3, HRAS, KRAS, NF1, NRAS
7MP:00053679.0CSF2, GATA2, HRAS, KRAS, NF1, PDGFRA
8MP:00030128.9FLT3, HRAS, KRAS, NRAS, PDGFRA, PTPN11
9MP:00053888.6CBL, CSF2, HRAS, KRAS, NF1, PDGFRA
10MP:00053868.4CBL, CSF2, DPM1, HRAS, KRAS, NF1
11MP:00053708.3CBL, GATA2, KRAS, NF1, NRAS, PTPN11
12MP:00028738.3GATA2, HRAS, KRAS, NF1, NRAS, PDGFRA
13MP:00107718.3CBL, CSF2, HRAS, KRAS, NF1, NRAS
14MP:00053878.2CBL, CSF2, FLT3, KRAS, NF1, NRAS
15MP:00053848.2CBL, CSF2, FLT3, GATA2, KRAS, NF1
16MP:00053858.1CBL, CSF2, GATA2, HRAS, KRAS, NF1
17MP:00053767.8CBL, CSF2, FLT3, GATA2, HRAS, KRAS
18MP:00053797.8CBL, CSF2, FLT3, GATA2, HRAS, KRAS
19MP:00053977.6CBL, CSF2, FLT3, GATA2, KRAS, NF1
20MP:00053787.4CBL, CSF2, FLT3, GATA2, HRAS, KRAS
21MP:00107687.3CBL, CSF2, DPM1, FLT3, GATA2, HRAS

Drugs & Therapeutics for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Drugs for Leukemia, Acute Myelomonocytic, Somatic, Somatic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 163)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Busulfanapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 154555-98-12478
Synonyms:
1, 4-Dimethanesulfonoxybutane
1, 4-Dimethylsulfonoxybutane
1, {4-Bis[methanesulfonoxy]butane}
1,4-BUTANEDIOL DIMETHANESULFONATE
1,4-Bis(methanesulfonoxy)butane
1,4-Bis(methanesulfonyloxy)butane
1,4-Bis[methanesulfonoxy]butane
1,4-Butanedi yl dimethanesulfonate
1,4-Butanediol dimethanesulfonate
1,4-Butanediol dimethanesulphonate
1,4-Butanediol dimethylsulfonate
1,4-Butanediol, dimethanesulfonate
1,4-Butanediol, dimethanesulphonate
1,4-Butanediyl dimethanesulfonate
1,4-Di(methylsulfonoxy)butane
1,4-Dimesyloxybutane
1,4-Dimethane sulfonyl oxybutane
1,4-Dimethanesulfonoxybutane
1,4-Dimethanesulfonoxylbutane
1,4-Dimethanesulfonyloxybutane
1,4-Dimethanesulphonyloxybutane
1,4-Dimethylsulfonoxybutane
1,4-Dimethylsulfonyloxybutane
2041 C. B
2041 C. B.
2041 C.B
2041 C.B.
4-((Methylsulfonyl)oxy)butyl methanesulfonate
4-methylsulfonyloxybutyl methanesulfonate
55-98-1
AC-198
AC1L1DRQ
AC1Q4GRQ
AI3-25012
AKOS003614975
AN 33501
Ambap55-98-1
B1022
B2635_FLUKA
B2635_SIGMA
BRN 1791786
BSPBio_001920
BUSULFAN (1,4-BUTANEDIOL, DIMETHANESULFONATE)
Bisulfex
Busilvex
Busulfan
Busulfan (JP15/USP/INN)
Busulfan GlaxoSmithKline Brand
Busulfan Orphan Brand
Busulfan Wellcome
Busulfan Wellcome Brand
Busulfan [INN:JAN]
Busulfano
Busulfano [INN-Spanish]
Busulfanum
Busulfanum [INN-Latin]
Busulfex
Busulphan
Busulphane
Butanedioldimethanesulfonate
Buzulfan
C.B. 2041
C6H14O6S2
CB 2041
CCRIS 418
CHEBI:28901
CHEMBL820
CID2478
CPD000058613
Citosulfan
D002066
D00248
DB01008
DivK1c_000847
EINECS 200-250-2
FT-0083567
G.T. 41
GT 2041
GT 41
Glaxo Wellcome Brand of Busulfan
GlaxoSmithKline Brand of Busulfan
Glyzophrol
HMS1920I07
HMS2091O09
HMS502K09
 
HSDB 7605
I09-1371
IDI1_000847
InChI=1/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3
KBio1_000847
KBio2_000512
KBio2_003080
KBio2_005648
KBio3_001420
KBioGR_000698
KBioSS_000512
LS-1358
Leucosulfan
MLS001076666
MYLERAN (TN)
Mablin
Methanesulfonic
Methanesulfonic acid, tetram ethylene ester
Methanesulfonic acid, tetramethylene ester
Mielevcin
Mielosan
Mielucin
Milecitan
Mileran
Misulban
Mitosan
Mitostan
MolPort-001-783-406
Myeleukon
Myeloleukon
Myelosan
Myelosanum
Mylecytan
Myleran
Myleran Tablets
Myleran tablets
Myleran, Busulfex, Busulfan
Mylerlan
NCGC00090905-01
NCGC00090905-02
NCGC00090905-03
NCGC00090905-04
NCGC00090905-05
NCGC00090905-06
NCGC00090905-07
NCI-C01592
NCI60_041640
NCIMech_000192
NINDS_000847
NSC 750
NSC-750
NSC-750sulphabutin
NSC750
Orphan Brand of Busulfan
Prestwick_989
S1692_Selleck
SAM002554887
SMR000058613
SPBio_000253
SPECTRUM1500152
ST50825921
Spectrum2_000067
Spectrum3_000320
Spectrum4_000259
Spectrum5_000928
Spectrum_000092
Sulfabutin
Sulfabutin (VAN)
Sulphabutin
Tetramethylene Dimethane Sulfonate
Tetramethylene bis(methanesulfonate)
Tetramethylene bis[methanesulfonate]
Tetramethylene dimethane sulfonate
Tetramethylene {bis[methanesulfonate]}
Tetramethylenester Kyseliny Methansulfonove
Tetramethylenester kyseliny methansulfonove
Tetramethylenester kyseliny methansulfonove [Czech]
UNII-G1LN9045DK
WLN: WS1&O4OSW1
Wellcome Brand of Busulfan
Wellcome, Busulfan
X 149
acid, tetramethylene ester
alkylating agent: crosslinks guanine residues
busulfan
butane-1,4-diyl dimethanesulfonate
n-Butane-1,3-di(methylsulfonate)
2
Cyclophosphamideapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 1293550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
3Alkylating AgentsPhase 4, Phase 3, Phase 2, Phase 14827
4Immunosuppressive AgentsPhase 4, Phase 3, Phase 2, Phase 113086
5Antirheumatic AgentsPhase 4, Phase 3, Phase 2, Phase 110956
6Antineoplastic Agents, AlkylatingPhase 4, Phase 3, Phase 2, Phase 14603
7
Cytarabineapproved, investigationalPhase 3, Phase 2, Phase 11117147-94-46253
Synonyms:
(beta-D-Arabinofuranosyl)cytosine
(beta-D-arabinofuranosyl)cytosine
1-.beta.-D-arabinofuranosyl-cytosine
1-Arabinofuranosylcytosine
1-beta -D-Arabinofaranosylcytosine
1-beta -D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone
1-beta -D-Arabinofuranosylcytosine
1-beta-D-Arabinofaranosylcytosine
1-beta-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone
1-beta-D-Arabinofuranosyl-Cytosine
1-beta-D-Arabinofuranosylcytosine
1-beta-D-Arabinofuranosylcytosine, Cytosine Arabinoside
1-beta-D-Arabinosyl-Cytosine
1-beta-D-Arabinosylcytosine
147-94-4
1beta -Arabinofuranasylcytosine
1beta -D-Arabinofuranosylcytosine
1beta -D-Arabinosylcytosine
1beta-Arabinofuranasylcytosine
1beta-D-Arabinofuranosylcytosine
1beta-D-Arabinosylcytosine
2(1H)-Pyrimidinone, 4-amino-1- -D-arabinofuranosyl- [CAS]
2(1H)-Pyrimidinone, 4-amino-1- -D-arabinofuranosyl
30399_FLUKA
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin [Czech]
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
4-Amino-1-b-D-arabinofuranosyl-2-(1H)-pyrimidinone
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinon
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinon [Czech]
4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
69-74-9 (hydrochloride)
AC-1075
AC1L1M4F
AC1Q52OJ
AI3-52329
AR3
Alexan
Ara-C
Ara-C, Cytosine Arabinoside, Cytosar-U, Cytarabine
Ara-Cytidine
AraC
Arabinocytidine
Arabinofuranosylcytosine
Arabinosyl Cytosine
Arabinosylcytosine
Arabitin
Aracytidine
Aracytin
Aracytine
Arafcyt
BIDD:GT0371
BIDD:PXR0139
BTB15125
Beta-cytosine arabinoside
C02961
C1768_SIGMA
C2035
C9H13N3O5
CCRIS 913
CHEBI:28680
CHEMBL803
CHX 3311
CID6253
CPD000449317
CYTARABINE (SEE ALSO CYTARABINE HYDROCHLORIDE 69-74-9)
Citarabina
Citarabina [INN-Spanish]
Cytarabin
Cytarabina
Cytarabine (JP15/USP/INN)
Cytarabine [USAN:INN:BAN:JAN]
 
Cytarabine liposome injection
Cytarabinoside
Cytarabinum
Cytarabinum [INN-Latin]
Cytarbel
Cytonal
Cytosar
Cytosar-U
Cytosine 1-beta-D-arabinofuranoside
Cytosine arabinofuranoside
Cytosine arabinose
Cytosine arabinoside
Cytosine arabinoside (VAN)
Cytosine beta-D-arabinofuranoside
Cytosine beta-D-arabinofuranoside hydrochloride
Cytosine beta-D-arabinoside
Cytosine, beta -D-arabinoside
Cytosine, beta-D-arabinoside
Cytosine-1-beta-D-arabinofuranoside
Cytosine-1-beta-D-arabinofuranoside hydrochloride
Cytosine-beta -D-arabinofuranoside
Cytosine-beta -arabinoside
Cytosine-beta-D-arabinofuranoside
Cytosine-beta-arabinoside
Cytosinearabinoside
D00168
DB00987
DepoCyte
Depocyt
Depocyt (TN)
Depocyt (liposomal)
Depocyte
EINECS 205-705-9
Erpalfa
FT-0082880
HMS2051K19
HMS2090A18
HSDB 3049
Intrathecal (injected into the spinal fluid) DepoCyt
Intrathecal cytarabine (also known as ara-C)
Iretin
LS-860
Lopac0_000316
MLS000758310
MLS001066340
MolPort-001-792-509
NCGC00093356-03
NCGC00093356-04
NCGC00093356-05
NCI-C04728
NSC 287459
NSC287459
S1648_Selleck
SAM001247012
SMR000449317
SR-01000075773-3
Spongocytidine
TL8001048
Tarabine
U 19920A
U-19,920
U-19920
UNII-04079A1RDZ
Udicil
ZINC03795098
beta -D-arabinosylcytosine
beta -arabinosylcytosine
beta -cytosine arabinoside
beta-Ara C
beta-Ara c
beta-Arabinosylcytosine
beta-Cytosine arabinoside
beta-D-Arabinosylcytosine
cytarabine
cytarabine liposome injection
cytosine-β-D-arabinofuranoside
8
LenograstimapprovedPhase 3, Phase 2, Phase 11220135968-09-1
Synonyms:
G-CSF (CHO cell derived)
Glycosylated recombinant G-CSF
Glycosylated recombinant granulocyte colony stimulating factor
 
Granulocyte colony stimulating factor 3 (CHO cell derived)
Granulocyte colony-stimulating factor lenograstim
Lenograstim (genetical recombination)
Lenograstim rDNA
9
Mycophenolate mofetilapproved, investigationalPhase 3, Phase 2, Phase 1952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
10
Mycophenolic acidapprovedPhase 3, Phase 2, Phase 195224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
11
MethotrexateapprovedPhase 3, Phase 2, Phase 115511959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
12
rituximabapprovedPhase 3, Phase 21692174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
13
EtoposideapprovedPhase 3, Phase 2, Phase 1126933419-42-036462
Synonyms:
(-)-Etoposide
121471-01-0
136598-18-0
201594-04-9
33419-42-0
35317-32-9
4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside
4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin
4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside
4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside
51854-34-3
76576-58-4
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one
AB00438905
AC1L1FN8
AC1L1VT3
AC1L6246
AC1NR4OG
AC1O4WGG
AC1O7M1N
AC1Q47JJ
Ambap33419-42-0
BPBio1_000673
BRD-K37798499-001-02-5
BSPBio_000611
Bio1_000489
Bio1_000978
Bio1_001467
C01576
CCRIS 2392
CHEBI:4911
CHEBI:588795
CHEMBL44657
CID11758093
CID284997
CID3310
CID36462
CID5284558
CID6419930
CID6610299
CPD000112002
D00125
DB00773
DEMETHY-EPIPODOPHYLLOTOXIN,ETHYLIDENE GLUCOSIDE,
Demethyl Epipodophyllotoxin Ethylidine Glucoside
Demethyl-epiodophyllotoxin ethylidene glucoside
Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
E0675
E1383_SIGMA
EINECS 251-509-1
EPE
EPEG
ETOP
Epipodophyllotoxin
Epipodophyllotoxin VP-16213
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
Eposide
Eposin
 
Eposin, Vepesid, VP-16, Toposar, Etoposide
Etopol
Etopophos
Etopophos (phosphate salt)
Etoposid
Etoposide
Etoposide (JP15/USP/INN)
Etoposide (VP16)
Etoposide [USAN:INN:BAN:JAN]
Etoposido
Etoposido [INN-Spanish]
Etoposidum
Etoposidum [INN-Latin]
Etosid
HMS1569O13
HMS2052N05
HMS2089F14
HSDB 6517
I06-0248
KBioSS_002410
LS-1214
Lastet
MLS000049957
MLS001074951
MLS001424283
MLS002153463
MLS002207239
MLS002222184
MolPort-003-983-431
MolPort-004-905-001
MolPort-004-955-161
NCGC00025056-02
NChemBio.2007.10-comp19
NK 171
NSC 141540
NSC-141540
NSC141540
Prestwick0_000396
Prestwick1_000396
Prestwick2_000396
Prestwick3_000396
Prestwick_211
S1225_Selleck
SAM001246880
SMR000112002
SPBio_002532
ST056353
Toposar
UNII-6PLQ3CP4P3
VP 16
VP 16 (pharmaceutical)
VP 16-213
VP 16213
VP-16
VP-16-213
VePESID (TN)
VePesid
Vepesid
Vepesid J
Vepeside
ZINC03830818
ZINC03938684
Zuyeyidal
etoposide
nchembio.573-comp8
nchembio873-comp2
trans-Etoposide
14
ThioguanineapprovedPhase 383154-42-72723601
Synonyms:
154-42-7
2 Amino 6 Purinethiol
2-Amino 6MP
2-Amino 6mp
2-Amino-1,7-dihydro-6H-purin-6-thion
2-Amino-1,7-dihydro-6H-purin-6-thion [Czech]
2-Amino-1,7-dihydro-6H-purine-6-thione
2-Amino-6-MP
2-Amino-6-mercaptopurine
2-Amino-6-merkaptopurin
2-Amino-6-merkaptopurin [Czech]
2-Amino-6-purinethiol
2-Amino-9H-purine-6-thiol
2-Aminopurin-6-thiol
2-Aminopurin-6-thiol [Czech]
2-Aminopurine-6(1H)-thione
2-Aminopurine-6-thiol
2-Thioguanine
2-amino-1,9-Dihydropurine-6-thione
2-amino-1H-purine-6(7H)-thione
2-amino-3,7-dihydropurine-6-thione
2-aminopurine-6-thiol
5580-03-0
6 Thioguanine
6-Mercapto-2-aminopurine
6-Mercaptoguanine
6-TG
6-Thioguanine
6-Thioguanine (6-TG)
6-Thioguanine, Thioguanine
A4660_SIGMA
A4882_SIGMA
AC-11125
AC1MC379
AI3-26078
AKOS003389499
BSPBio_001994
BW 5071
C07648
C5H7N5S
CCRIS 8997
CHEBI:136864
CHEMBL727
CID2723601
D013866
D08603
DB00352
DX4
DivK1c_000428
EINECS 205-827-2
FT-0083572
Glaxo Wellcome Brand of Thioguanine
Glaxo Wellcome Brand of Tioguanine
GlaxoSmithKline Brand of Thioguanine
GlaxoSmithKline Brand of Tioguanine
Guanine, thio- (VAN)
HMS1921E09
HMS2092M11
HMS501F10
HSDB 2504
I14-1541
IDI1_000428
KBio1_000428
KBio2_000715
KBio2_002476
KBio2_003283
KBio2_005044
 
KBio2_005851
KBio2_007612
KBio3_001494
KBio3_002954
KBioGR_001452
KBioGR_002476
KBioSS_000715
KBioSS_002483
LS-888
LT00455187
Lanvis
Lanvis (TN)
MLS001333131
MLS001333132
MolPort-000-929-106
MolPort-001-813-204
MolPort-003-984-174
NCGC00094792-01
NCGC00094792-02
NCGC00094792-03
NCI60_041643
NCIOpen2_004153
NINDS_000428
NSC 752
NSC-752
NSC752
S1774_Selleck
SBB067147
SMP2_000326
SMR000857244
SPBio_000849
SPECTRUM1500573
ST50298831
Spectrum2_000695
Spectrum3_000577
Spectrum4_000926
Spectrum5_001455
Spectrum_000235
T0212
TG
THG
Tabloid
ThG
Thioguanin GSK
Thioguanin-GSK
ThioguaninGSK
Thioguanine
Thioguanine Hemihydrate
Thioguanine Monosodium Salt
Thioguanine Tabloid
Thioguanine [USAN:BAN]
Tioguanin
Tioguanina
Tioguanina Wellcome
Tioguanina [INN-Spanish]
Tioguanine
Tioguanine (INN)
Tioguanine GlaxoSmithKline Brand
Tioguaninum
Tioguaninum [INN-Latin]
UNII-FTK8U1GZNX
UNII-WIX31ZPX66
WLN: T56 BNM FYM INJ FUS HZ
Wellcome Brand of Thioguanine
Wellcome U3B
ZINC18085533
cMAP_000061
purine antimetabolite: antimetabolite: inhibits nucleic acid replication
thioguanine
15
Hydrocortisoneapproved, vet_approvedPhase 366750-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
16
DaunorubicinapprovedPhase 327320830-81-330323
Synonyms:
(+)-Daunomycin
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside
(7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione
(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro--6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
11006-54-5
11048-29-6
1407-15-4
149541-57-1
20830-81-3
23942-76-9
27576-81-4
28020-80-6
AB00514669
AC1L1JCP
AC1Q29OI
AI3-52942
Acetyladriamycin
Anthracyline
Antibiotics From Streptomyces Coeruleorubidus
Antibiotics from Streptomyces coeruleorubidus
BPBio1_000389
BRD-K43389675-003-02-7
BRN 1445583
BSPBio_000353
C01907
CCRIS 914
CHEBI:41977
CHEMBL178
CID30323
Cerubidin
Cerubidine
D07776
DAUNORUBICIN HCL
DB00694
DM1
Daunamycin
Daunarubicinum
Dauno-Rubidomycine
DaunoXome
DaunoXome (TN)
Daunoblastin
Daunoblastine
Daunomycin
 
Daunomycin Hydrochloride
Daunomycin, Hydrochloride
Daunorrubicina
Daunorubicin
Daunorubicin (INN)
Daunorubicin (liposomal)
Daunorubicin Hcl
Daunorubicin Hydrochloride
Daunorubicin [INN:BAN]
Daunorubicin, Hydrochloride
Daunorubicina
Daunorubicine
Daunorubicinum
Daunorubicinum [INN-Latin]
Daunoxome
EINECS 244-069-7
FI 6339
FI6339
HMS2089H04
HMS2091K06
HSDB 5095
LMPK13050002
LS-187381
LS-997
Leukaemomycin C
MolPort-002-533-961
NCGC00024246-05
NCGC00024246-06
NCGC00025173-01
NCI-C04693
NChemBio.2007.10-comp14
NSC 83142
NSC-82151
Ondena
Prestwick3_000487
RCRA waste no. U059
RP 13057
Rcra Waste No. U059
Rp 13057 Hydrochloride
Rubidomycin
Rubidomycin Hydrochloride
Rubomycin
Rubomycin C
Tocris-1467
UNII-ZS7284E0ZP
VS-103
daunorubicin
nchembio723-comp2
17
AsparaginaseapprovedPhase 32299015-68-3
Synonyms:
Asparaginase (E. coli)
 
Elspar
L-asparagine amidohydrolase
Putative L-asparaginase precursor
18
ThiotepaapprovedPhase 3, Phase 2, Phase 122652-24-45453
Synonyms:
 
Thioplex
19
Cyclosporineapproved, investigational, vet_approvedPhase 3, Phase 2, Phase 192279217-60-0, 59865-13-35284373, 6435893
Synonyms:
1c5f
1cyn
30024_FLUKA
30024_SIGMA
59865-13-3
79217-60-0
AC1L1EQW
AC1NQXJE
AC1NR4C4
AC1NUQK3
AC1NUZNC
AC1O5KOG
AC1Q2UDG
Ambap59865-13-3
Ambotz59865-13-3
Antibiotic S 7481F1
BMT-ABA-SAR-MLE-VAL-MLE-ALA-ALA-MLE-MLE-MVA
BMT-ABA-SAR-MLE-VAL-MLE-ALA-DAL-MLE-MLE-MVA
BPBio1_000496
BRD-A64290322-001-01-6
BRD-A69815203-001-04-3
BRD-K13533483-001-03-0
BSPBio_000450
BSPBio_001596
BSPBio_003186
C 3662
C05086
C1832_SIGMA
C3662_SIGMA
C62H111N11O12
CB-01-09 MMX
CHEBI:106343
CHEBI:328305
CHEBI:4031
CHEMBL160
CHEMBL386389
CHEMBL532318
CID2909
CID5280754
CID5284373
CID5458585
CID5497195
CID6435893
CSA
CYCLOSPORIN A (SEE ALSO TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A))
CYCLOSPORIN A, USP
Ciclosporin
Ciclosporin (JP15)
Ciclosporina
Ciclosporine
Ciclosporinum
Cipol N
Cipol-N
Consupren
Consupren S
CsA
CsA & IFN.alpha.
CyA
Cyclokat
Cyclosporin
Cyclosporin A
Cyclosporin A & IFN.alpha.
Cyclosporin A Implant
Cyclosporin A, Tolypocladium inflatum
Cyclosporine (USP)
Cyclosporine A
Cyclosporine [USAN]
D00184
DE-076
DivK1c_000871
EU-0100242
Equoral
GNF-Pf-2808
Gengraf
Gengraf (TN)
HMS1569G12
HMS1791P18
HMS1921L20
HMS1989P18
HMS2089A09
HMS2092F06
HMS502L13
Helv Chim Acta 60: 1568 (1977)
 
I06-0379
I06-0966
IDI1_000871
KBio1_000871
KBio2_000780
KBio2_003348
KBio2_005916
KBio3_002686
KBioGR_001898
KBioSS_000780
LMPK14000003
LS-257
LS-58836
Lopac0_000242
MLS000028376
MLS001333756
MLS002153454
MLS002207033
Mitogard
Modusik-A
MolPort-000-760-988
MolPort-005-934-008
MolPort-006-705-994
NCGC00093704-01
NCGC00093704-02
NCGC00093704-03
NCGC00093704-04
NCGC00093704-05
NCGC00093704-06
NCGC00093704-07
NCGC00093704-08
NCGC00164258-01
NCGC00164258-02
NINDS_000871
NSC290193
Neoplanta
Neoral
Neoral (TN)
NeuroSTAT
Nova-22007
OL 27-400
OL-27400
OLO-400
Papilock
Prestwick2_000435
Prestwick3_000435
Prestwick_731
Pulminiq
Ramihyphin A
Restasis
Restasis (TN)
S-Neoral
S1514_Selleck
SDZ-OXL 400
SMR000058578
SPBio_001467
SPECTRUM1502202
ST-603
Sandimmun
Sandimmun Neoral
Sandimmune
Sandimmune (TN)
Sandimmune, Gengraf, Restasis, Atopica, Sangcya, Cyclosporine
Sang-2000
Sang-35
SangCyA
Sangcya
Sigmasporin
Sigmasporin Microoral
Spectrum2_001484
Spectrum3_001593
Spectrum4_001279
Spectrum5_001628
Spectrum_000300
TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A)
Vekacia
Zyclorin
cyclophorine
cyclosporin A
cyclosporine
from Tolypocladium inflatum (Trichoderma polysporin)
nchembio.184-comp6
nchembio.301-comp5
nchembio.342-comp1
20
LorazepamapprovedPhase 3124846-49-13958
Synonyms:
(+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
(+/-)-Lorazepam
(±)-Lorazepam
5-25-02-00248 (Beilstein Handbook Reference)
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one
7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
846-49-1
AC1L1H3H
AHP Brand of Lorazepam
Almazine
Alzapam
Anxiedin
Anxira
Anzepam
Aplacasse
Aplacassee
Apo Lorazepam
Apo-Lorazepam
ApoLorazepam
Apotex Brand of Lorazepam
Aripax
Ativan
Ativan (TN)
Azurogen
BRN 0759084
Baxter Brand of Lorazepam
Bonatranquan
Bonton
CHEBI:116959
CHEMBL580
CID3958
CPD000058410
D00365
D008140
DB00186
DEA No. 2885
Delormetazepam
Demethyllormetazepam
Desitin Brand of Lorazepam
DivK1c_000965
Dolorgiet Brand of Lorazepam
Donix
Duralozam
Durazolam
EINECS 212-687-6
Efasedan
Emotion
Emotival
Equitam
HMS2052H07
HMS503A11
IDI1_000965
Idalprem
KBio1_000965
Kalmalin
L-Lorazepam Acetate
L1764_SIGMA
LS-34141
Larpose
Laubeel
Llorens Brand of Lorazepam
Lomesta
Lopam
Lorabenz
Lorafen
Loram
Lorans
Lorapam
Lorat
Lorax
Loraz
Lorazene
Lorazep
Lorazepam (JP15/USP/INN)
Lorazepam AHP Brand
Lorazepam Apotex Brand
Lorazepam Baxter Brand
Lorazepam Desitin Brand
Lorazepam Dolorgiet Brand
Lorazepam Fabra
Lorazepam Genericon
Lorazepam Intensol
Lorazepam Lannacher
Lorazepam Llorens Brand
Lorazepam Medical
Lorazepam Medical Brand
Lorazepam Medix Brand
Lorazepam Novartis Brand
Lorazepam Novopharm Brand
Lorazepam Nu-Pharm Brand
Lorazepam Riemser Brand
Lorazepam Wyeth Brand
Lorazepam [USAN:INN:BAN:JAN]
Lorazepam ct-Arzneimittel Brand
 
Lorazepam neuraxpharm
Lorazepam neuraxpharm Brand
Lorazepam preservative free
Lorazepam ratiopharm
Lorazepam ratiopharm Brand
Lorazepam-Efeka
Lorazepam-neuraxpharm
Lorazepam-ratiopharm
Lorazepamum
Lorazepamum [INN-Latin]
Lorazepan Chobet
Lorazepan Richet
Lorazin
Lorazon
Lorenin
Loridem
Lorivan
Lormetazepam
Lorsedal
Lorsilan
Lorzem
Lozepam
Max Pax
Medical Brand of Lorazepam
Medical, Lorazepam
Medix Brand of Lorazepam
Merck dura Brand of Lorazepam
Merlit
Methyllorazepam
MolPort-002-051-769
N-Methyllorazepam
NCGC00159439-02
NINDS_000965
NSC 289758
NSC289758
Nervistop L
Nervistopl
Norlormetazepam
Novartis Brand of Lorazepam
Novhepar
Novo Lorazem
Novo-Lorazem
Novolorazem
Novopharm Brand of Lorazepam
Nu Loraz
Nu Pharm Brand of Lorazepam
Nu-Loraz
Nu-Pharm Brand of Lorazepam
NuLoraz
O-Chlorooxazepam
O-Chloroxazepam
Orfidal
Orfidal Wyeth
Pro Dorm
Pro dorm
Psicopax
Punktyl
Quait
Renaquil
Riemser Brand of Lorazepam
Rocosgen
SAM001246833
Securit
Sedatival
Sedazin
Sedicepan
Sedizepan
Serra Pamies Brand of Lorazepam
Sidenar
Silence
Sinestron
Somagerol
Stapam
Tavor
Temesta
Tolid
Tranqipam
Trapax
UNII-O26FZP769L
Upan
Vigiten
WLN: T67 GMV JN IHJ CG IQ KR BG
WY4036
Wy 4036
Wy-4036
Wyeth Brand of Lorazepam
Wyeth, Orfidal
Wypax
ct Arzneimittel Brand of Lorazepam
ct-Arzneimittel Brand of Lorazepam
lorazep von ct
lorazepam
lorazepam (Ativan)
nchembio747-comp26
neuraxpharm Brand of Lorazepam
o-Chlorooxazepam
o-Chloroxazepam
ratiopharm Brand of Lorazepam
21
leucovorinapproved, NutraceuticalPhase 3, Phase 2, Phase 1323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
22
Folic Acidapproved, nutraceutical, vet_approvedPhase 3, Phase 2, Phase 1439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
23
Butyric AcidexperimentalPhase 3380107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
1-propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
Butyric acid
 
Butyricum acidum
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
N-butanoic acid
N-butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
24Folic Acid AntagonistsPhase 3, Phase 2, Phase 12257
25Anti-Bacterial AgentsPhase 3, Phase 2, Phase 111226
26Anti-Infective AgentsPhase 3, Phase 2, Phase 122062
276-MercaptopurinePhase 3202
28Vitamin B ComplexPhase 3, Phase 2, Phase 14337
29AntimetabolitesPhase 3, Phase 2, Phase 112054
30Dermatologic AgentsPhase 3, Phase 2, Phase 15806
31Anti-Inflammatory AgentsPhase 3, Phase 2, Phase 110729
32Nucleic Acid Synthesis InhibitorsPhase 3, Phase 2, Phase 14962
33Antiviral AgentsPhase 3, Phase 2, Phase 19967
34Antimetabolites, AntineoplasticPhase 3, Phase 2, Phase 17361
35Antibiotics, AntitubercularPhase 3, Phase 2, Phase 17180
36AcyclovirPhase 3183
37Adjuvants, ImmunologicPhase 3, Phase 1, Phase 22554
38Etoposide phosphatePhase 3, Phase 2, Phase 11269
39Antineoplastic Agents, PhytogenicPhase 3, Phase 2, Phase 15602
40valacyclovirPhase 3106
41Topoisomerase InhibitorsPhase 3, Phase 2, Phase 15069
42Muromonab-CD3Phase 3, Phase 239
43Calcium, DietaryPhase 35713
44ImmunoglobulinsPhase 3, Phase 26394
45AntibodiesPhase 3, Phase 26394
46Cortisol succinatePhase 3667
47Bone Density Conservation AgentsPhase 33376
48Hydrocortisone-17-butyratePhase 3332
49Hydrocortisone acetatePhase 3667
50Hydrocortisone 17-butyrate 21-propionatePhase 3667

Interventional clinical trials:

(show top 50)    (show all 114)
idNameStatusNCT IDPhase
1Busulfan and Cyclophosphamide Instead of Total Boby Irradiation (TBI) and Cyclophosphamide for Hematological Malignancies Hematocrit (HCT)Not yet recruitingNCT01339988Phase 4
2Donor Stem Cell Transplant With or Without Chemotherapy in Treating Children With Primary Myelodysplastic SyndromeUnknown statusNCT00047268Phase 3
3Stem Cell Transplantation for Patients With Hematologic MalignanciesCompletedNCT00152139Phase 3
4Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell TransplantCompletedNCT01305200Phase 3
5Haploidentical Stem Cell Transplantation for Patients With Hematologic MalignanciesCompletedNCT00186823Phase 3
6Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic SyndromeCompletedNCT00003593Phase 3
7Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic CancerCompletedNCT00265837Phase 3
8Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical TrialCompletedNCT00750009Phase 3
9A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their FamiliesCompletedNCT00782145Phase 3
10Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell TransplantationCompletedNCT00045292Phase 3
11Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell TransplantCompletedNCT00305851Phase 3
12Myeloablative Hematopoietic Progenitor Cell Transplantation (HPCT) for Pediatric MalignanciesRecruitingNCT00619879Phase 3
13Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other DiseasesTerminatedNCT00450450Phase 3
14Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD)TerminatedNCT00089141Phase 3
15Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant DiseasesUnknown statusNCT00084695Phase 2
16Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic LeukemiaCompletedNCT00025038Phase 2
17A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic MalignanciesCompletedNCT01036009Phase 2
18Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic MalignanciesCompletedNCT01093586Phase 2
19Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic CancerCompletedNCT00118352Phase 2
20Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic CancerCompletedNCT00489203Phase 2
21Stem Cell Transplantation as Immunotherapy for Hematologic MalignanciesCompletedNCT00143559Phase 2
22Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell TransplantCompletedNCT00309907Phase 2
23Haploidentical Stem Cell Transplant for Treatment Refractory Hematological MalignanciesCompletedNCT00145613Phase 2
24T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients With Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, or Aplastic AnemiaCompletedNCT00002718Phase 2
25Quality of Life of Adult Cancer Survivors Who Have Undergone a Previous Bone Marrow or Peripheral Stem Cell Transplant for a Childhood Hematologic CancerCompletedNCT00126477Phase 2
26Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Nonmalignant Hematologic DiseaseCompletedNCT00003913Phase 2
27Donor Stem Cell Transplant in Treating Patients With Hematologic CancerCompletedNCT00054327Phase 2
28Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic CancerCompletedNCT00014469Phase 2
29Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid CancerCompletedNCT00346359Phase 2
30Non-Ablative Allo HSCT For Hematologic Malignancies or SAACompletedNCT00006379Phase 2
31Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell TransplantationCompletedNCT00089037Phase 1, Phase 2
32Tacrolimus and Mycophenolate Mofetil in Preventing Acute Graft-Versus-Host Disease in Patients With Advanced Hematologic Cancer Who Are Undergoing Donor Stem Cell TransplantationCompletedNCT00096096Phase 2
33Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer TreatmentCompletedNCT00066248Phase 2
34Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological CancerCompletedNCT00589563Phase 2
35Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell TransplantCompletedNCT00410657Phase 2
36Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous DiseaseCompletedNCT00118326Phase 1, Phase 2
37Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell TransplantCompletedNCT00357084Phase 2
38Study With Azacitidine in Pediatric Subjects With Newly Diagnosed Advanced Myelodysplastic Syndrome (MDS) and Juvenile Myelomonocytic Leukemia (JMML)RecruitingNCT02447666Phase 2
39Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML)RecruitingNCT00167219Phase 1, Phase 2
40CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell TransplantRecruitingNCT02061800Phase 1, Phase 2
41Phase II Trial of Myeloablative Conditioning & Transplantation of Partially HLA-mismatched Marrow With Post-transplant Cyclophosphamide for Peds Pts w/ Hematologic MalignanciesRecruitingNCT02120157Phase 2
42Haploidentical BMT With Post-Transplant Cyclophosphamide and BendamustineRecruitingNCT02996773Phase 1, Phase 2
43A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological MalignanciesRecruitingNCT01384513Phase 2
44Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic MalignanciesRecruitingNCT01760655Phase 2
45Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior TransplantationRecruitingNCT02790515Phase 2
46Myeloablative Umbilical Cord Blood Transplantation in Hematological DiseasesRecruitingNCT00309842Phase 2
47Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic LeukemiaActive, not recruitingNCT01824693Phase 2
48Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell TransplantationActive, not recruitingNCT02458235Phase 2
49Treosulfan-based Conditioning in Paediatric Patients With Haematological MalignanciesActive, not recruitingNCT02333058Phase 2
50Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic CancerActive, not recruitingNCT00006251Phase 1, Phase 2

Search NIH Clinical Center for Leukemia, Acute Myelomonocytic, Somatic, Somatic

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Stem-cell-based therapeutic approaches for Leukemia, Acute Myelomonocytic, Somatic, Somatic:
Hemacord
Embryonic/Adult Cultured Cells Related to Leukemia, Acute Myelomonocytic, Somatic, Somatic:
Umbilical cord blood-derived hematopoietic progenitor cells (HEMACORD, PMID: 9828244


Cochrane evidence based reviews: leukemia, myelomonocytic, juvenile

Genetic Tests for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Genetic tests related to Leukemia, Acute Myelomonocytic, Somatic, Somatic:

id Genetic test Affiliating Genes
1 Juvenile Myelomonocytic Leukemia27

Anatomical Context for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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MalaCards organs/tissues related to Leukemia, Acute Myelomonocytic, Somatic, Somatic:

36
Lymph node

Publications for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Variations for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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UniProtKB/Swiss-Prot genetic disease variations for Leukemia, Acute Myelomonocytic, Somatic, Somatic:

70 (show all 18)
id Symbol AA change Variation ID SNP ID
1ARHGAP26p.Asn417SerVAR_013623rs121918546
2KRASp.Gly12AspVAR_016026rs121913529
3KRASp.Gly12SerVAR_016028rs121913530
4KRASp.Gly13AspVAR_016029rs112445441
5NRASp.Gly13AspVAR_063084rs121434596
6NRASp.Gly12AspVAR_071129rs121913237
7PTPN11p.Asp61ValVAR_015991rs121918461
8PTPN11p.Asp61TyrVAR_015992
9PTPN11p.Glu69LysVAR_015993
10PTPN11p.Ala72ThrVAR_015996rs121918453
11PTPN11p.Ala72ValVAR_015997rs121918454
12PTPN11p.Glu76AlaVAR_015998rs121918465
13PTPN11p.Glu76GlyVAR_015999rs121918465
14PTPN11p.Glu76LysVAR_016000rs28933388
15PTPN11p.Glu76ValVAR_016001rs121918465
16PTPN11p.Gly507AlaVAR_016002rs397507546
17PTPN11p.Gly507ArgVAR_016003rs397507545
18SETBP1p.Asp868AsnVAR_063807rs267607042

Clinvar genetic disease variations for Leukemia, Acute Myelomonocytic, Somatic, Somatic:

5 (show all 19)
id Gene Variation Type Significance SNP ID Assembly Location
1KRASNM_ 033360.3(KRAS): c.38G> A (p.Gly13Asp)SNVPathogenic/ Likely pathogenicrs112445441GRCh37Chr 12, 25398281: 25398281
2KRASNM_ 004985.4(KRAS): c.35G> A (p.Gly12Asp)SNVPathogenic/ Likely pathogenicrs121913529GRCh37Chr 12, 25398284: 25398284
3KRASNM_ 004985.4(KRAS): c.35G> T (p.Gly12Val)SNVPathogenic/ Likely pathogenicrs121913529GRCh37Chr 12, 25398284: 25398284
4KRASNM_ 033360.3(KRAS): c.34G> A (p.Gly12Ser)SNVPathogenicrs121913530GRCh37Chr 12, 25398285: 25398285
5PTPN11NM_ 002834.4(PTPN11): c.226G> A (p.Glu76Lys)SNVPathogenic/ Likely pathogenicrs121918464GRCh37Chr 12, 112888210: 112888210
6PTPN11NM_ 002834.4(PTPN11): c.227A> T (p.Glu76Val)SNVPathogenicrs121918465GRCh37Chr 12, 112888211: 112888211
7PTPN11NM_ 002834.4(PTPN11): c.227A> G (p.Glu76Gly)SNVPathogenic/ Likely pathogenicrs121918465GRCh37Chr 12, 112888211: 112888211
8PTPN11NM_ 002834.4(PTPN11): c.227A> C (p.Glu76Ala)SNVPathogenic/ Likely pathogenicrs121918465GRCh37Chr 12, 112888211: 112888211
9NRASNM_ 002524.4(NRAS): c.38G> A (p.Gly13Asp)SNVPathogenic/ Likely pathogenicrs121434596GRCh37Chr 1, 115258744: 115258744
10CBLNM_ 005188.3(CBL): c.1228-2A> GSNVPathogenic/ Likely pathogenicrs727504426GRCh37Chr 11, 119149218: 119149218
11PTPN11NM_ 002834.4(PTPN11): c.181G> T (p.Asp61Tyr)SNVPathogenicrs397507510GRCh37Chr 12, 112888165: 112888165
12CBLNM_ 005188.3(CBL): c.1112A> G (p.Tyr371Cys)SNVPathogenicrs387906666GRCh37Chr 11, 119148892: 119148892
13NF1NM_ 000267.3(NF1): c.4614G> A (p.Trp1538Ter)SNVPathogenicrs137854555GRCh37Chr 17, 29588828: 29588828
14NF1NF1, IVS34, G-A, +18SNVPathogenic
15NF1NM_ 000267.3(NF1): c.1642-8A> GSNVPathogenicrs267606602GRCh37Chr 17, 29548860: 29548860
16NRASNM_ 002524.4(NRAS): c.35G> A (p.Gly12Asp)SNVPathogenic/ Likely pathogenicrs121913237GRCh37Chr 1, 115258747: 115258747
17ARHGAP26NM_ 015071.5(ARHGAP26): c.1250A> G (p.Asn417Ser)SNVPathogenicrs121918546GRCh37Chr 5, 142421420: 142421420
18ARHGAP26ARHGAP26, 52-BP INSinsertionPathogenic
19ARHGAP26ARHGAP26, 74-BP INSinsertionPathogenic

Expression for genes affiliated with Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Search GEO for disease gene expression data for Leukemia, Acute Myelomonocytic, Somatic, Somatic.

Pathways for genes affiliated with Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Pathways related to Leukemia, Acute Myelomonocytic, Somatic, Somatic according to GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.9CBL, HRAS, PTPN11
29.9CBL, HRAS, PTPN11
39.9HRAS, KRAS, NRAS
49.9HRAS, KRAS, NRAS
5
Show member pathways
9.9HRAS, KRAS, NRAS
69.9HRAS, KRAS, NRAS
79.9HRAS, KRAS, NRAS
89.9HRAS, KRAS, NRAS
99.9HRAS, KRAS, NRAS
109.9HRAS, KRAS, NRAS
11
Show member pathways
9.9HRAS, KRAS, NRAS
12
Show member pathways
9.9HRAS, KRAS, NRAS
139.9HRAS, KRAS, NRAS
149.9HRAS, KRAS, NRAS
159.9HRAS, KRAS, NRAS
169.9HRAS, KRAS, NRAS
179.9HRAS, KRAS, NRAS
18
Show member pathways
9.9HRAS, KRAS, NRAS
199.9CSF2, HRAS, NF1
209.9CBL, PTPN11, STAT5B
21
Show member pathways
9.8HRAS, PTPN11, STAT5B
22
Show member pathways
9.8HRAS, PTPN11, STAT5B
23
Show member pathways
9.8HRAS, KRAS, NF1, PTPN11
24
Show member pathways
9.8HRAS, KRAS, NRAS, PTPN11
259.8HRAS, KRAS, NRAS, PTPN11
26
Show member pathways
9.8HRAS, KRAS, NF1, NRAS
27
Show member pathways
9.8HRAS, KRAS, NF1, NRAS
289.8HRAS, KRAS, NF1, NRAS
299.8CSF2, CSF2RA, FLT3
30
Show member pathways
9.7CBL, HRAS, KRAS, NRAS
319.7CSF2, GATA2, RUNX1
32
Show member pathways
9.7FLT3, HRAS, KRAS, NRAS
33
Show member pathways
9.7HRAS, KRAS, NRAS, PDGFRA
34
Show member pathways
9.7HRAS, KRAS, NRAS, PDGFRA
35
Show member pathways
9.6CBL, HRAS, PTPN11, STAT5B
369.6CBL, HRAS, PTPN11, STAT5B
37
Show member pathways
9.6CBL, HRAS, PTPN11, STAT5B
38
Show member pathways
9.6HRAS, KRAS, NRAS, STAT5B
399.6HRAS, KRAS, NRAS, STAT5B
409.6HRAS, KRAS, NRAS, STAT5B
41
Show member pathways
9.6HRAS, KRAS, NRAS, STAT5B
42
Show member pathways
9.6HRAS, KRAS, NRAS, STAT5B
43
Show member pathways
9.6CBL, HRAS, KRAS, NRAS, PTPN11
44
Show member pathways
9.6CBL, HRAS, KRAS, NRAS, PTPN11
45
Show member pathways
9.6CBL, HRAS, KRAS, NRAS, PTPN11
469.6CBL, HRAS, KRAS, NRAS, PTPN11
47
Show member pathways
9.6CBL, HRAS, KRAS, NRAS, PTPN11
489.6CBL, FLT3, PDGFRA, SPRED1
49
Show member pathways
9.6HRAS, KRAS, NRAS, PDGFRA, PTPN11
50
Show member pathways
9.5HRAS, KRAS, NF1, NRAS, PDGFRA

GO Terms for genes affiliated with Leukemia, Acute Myelomonocytic, Somatic, Somatic

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Cellular components related to Leukemia, Acute Myelomonocytic, Somatic, Somatic according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00058298.6ARHGAP26, CBL, FLT3, HRAS, KRAS, MLLT11
2nucleusGO:00056347.3CBL, DPM1, FLT3, GATA2, HRAS, MLLT11

Biological processes related to Leukemia, Acute Myelomonocytic, Somatic, Somatic according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1forebrain astrocyte developmentGO:002189710.9KRAS, NF1
2dendritic cell differentiationGO:009702810.8CSF2, FLT3
3myeloid progenitor cell differentiationGO:000231810.8FLT3, TET2
4luteinizationGO:000155310.7PDGFRA, STAT5B
5ERBB2 signaling pathwayGO:003812810.7HRAS, KRAS, NRAS
6cellular response to epidermal growth factor stimulusGO:007136410.6CBL, PTPN11, STAT5B
7homeostasis of number of cells within a tissueGO:004887310.6GATA2, KRAS, PTPN11
8axon guidanceGO:000741110.5HRAS, KRAS, NRAS, PTPN11
9positive regulation of DNA replicationGO:004574010.5CSF2, HRAS, PDGFRA
10leukocyte migrationGO:005090010.5HRAS, KRAS, NRAS, PTPN11
11positive regulation of MAP kinase activityGO:004340610.4FLT3, HRAS, KRAS
12positive regulation of phosphatidylinositol 3-kinase signalingGO:001406810.4CBL, FLT3, PDGFRA
13regulation of synaptic transmission, GABAergicGO:003222810.4KRAS, NF1
14fibroblast growth factor receptor signaling pathwayGO:000854310.4CBL, PTPN11, SHOC2, SPRED1
15epidermal growth factor receptor signaling pathwayGO:000717310.3CBL, HRAS, KRAS, NRAS, PTPN11
16regulation of long-term neuronal synaptic plasticityGO:004816910.3HRAS, KRAS, NF1
17cytokine-mediated signaling pathwayGO:001922110.2CSF2RA, FLT3, KRAS, STAT5B
18hemopoiesisGO:003009710.2FLT3, GATA2, RUNX1, TET2
19response to isolation stressGO:003590010.1HRAS, KRAS
20peptidyl-tyrosine phosphorylationGO:00181089.9CSF2, CSF2RA, FLT3, PDGFRA, STAT5B
21Ras protein signal transductionGO:00072659.9HRAS, KRAS, NF1, NRAS, SHOC2
22positive regulation of cell proliferationGO:00082849.8CSF2, FLT3, HRAS, KRAS, PDGFRA, STAT5B
23positive regulation of GTPase activityGO:00435479.8ARHGAP26, CSF2, CSF2RA, HRAS, NF1, PDGFRA
24MAPK cascadeGO:00001659.5CSF2, CSF2RA, HRAS, KRAS, NF1, NRAS

Molecular functions related to Leukemia, Acute Myelomonocytic, Somatic, Somatic according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glucocorticoid receptor bindingGO:003525910.8FLT3, STAT5B
2protein tyrosine kinase bindingGO:199078210.3CBL, PTPN11
3protein complex bindingGO:003240310.3FLT3, KRAS, NRAS, PDGFRA
4vascular endothelial growth factor-activated receptor activityGO:000502110.0FLT3, PDGFRA
5protein tyrosine kinase activityGO:00047139.6CSF2, CSF2RA, FLT3, PDGFRA, STAT5B
6protein bindingGO:00055157.1ARHGAP26, CBL, CSF2, CSF2RA, DPM1, FLT3

Sources for Leukemia, Acute Myelomonocytic, Somatic, Somatic

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet