Leukemia, Acute Promyelocytic, Pml/rara Type malady

MalaCards: Leukemia, Acute Promyelocytic, Pml/rara Type, also known as leukemia, is related to chronic lymphocytic leukemia and chronic myeloid leukemia. An important gene associated with Leukemia, Acute Promyelocytic, Pml/rara Type is PML (promyelocytic leukemia). The drugs isotretinoin and methotrexate have been mentioned in the context of this disorder.

leukemia, acute promyelocytic, pml/rara type 33 leukemia 43

Diseases related to leukemia, acute promyelocytic, pml/rara type by text searches and GeneDecks gene sharing:

(show top 50)    (show all 303)

id	Related Disease	Score	Top Affiliating Genes
1	chronic lymphocytic leukemia	13.1
2	chronic myeloid leukemia	12.4
3	acute promyelocytic leukemia	12.0
4	human t-cell leukemia virus type 1	10.9
5	hairy cell leukemia	10.6
6	myelomonocytic leukemia	10.3
7	monocytic leukemia	10.0
8	megakaryoblastic leukemia	9.6
9	juvenile myelomonocytic leukemia	9.5
10	acute monocytic leukemia	9.2
11	leukemia/lymphoma, t-cell	9.2
12	chronic myelomonocytic leukemia	9.1
13	down syndrome	9.1
14	acute megakaryoblastic leukemia	8.9
15	prolymphocytic leukemia	8.9
16	t-cell prolymphocytic leukemia	8.6
17	hematopoiesis	8.5
18	acute myelomonocytic leukemia	8.4
19	stem cell leukemia	8.2
20	mast-cell leukemia	8.2
21	chronic leukemia	8.1
22	acute t cell leukemia	7.8
23	plasma cell leukemia	7.8
24	retinoblastoma	7.8
25	acute biphenotypic leukemia	7.7
26	lymphoblastic lymphoma	7.7
27	t-cell large granular lymphocyte leukemia	7.7
28	acute lymphoblastic leukemia, childhood	7.6
29	chronic neutrophilic leukemia	7.6
30	mantle cell lymphoma	7.5
31	adult acute lymphocytic leukemia	7.4
32	severe congenital neutropenia	7.3
33	acute myeloid leukemia, adult	7.2
34	b cell prolymphocytic leukemia	7.2
35	dna topoisomerase ii	7.2
36	combined immunodeficiency	7.1
37	familial chronic lymphocytic leukemia	7.1
38	hypereosinophilic syndrome	7.1
39	mastocytosis	7.1
40	neuroblastoma	7.1
41	natural killer cell leukemia	7.1
42	severe combined immunodeficiency	7.1
43	eosinophilia	6.9
44	familial acute myeloid leukemia (aml) with mutated cebpa	6.9
45	glucocorticoid resistance	6.9
46	infertility	6.9
47	burkitt's lymphoma	6.9
48	familial acute myeloid leukemia with mutated cebpa	6.8
49	fanconi's anemia	6.8
50	human t-cell leukemia virus type 2	6.8

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 cytarabine, cytarabine liposome, doxorubicin hydrochloride, irinotecan, irinotecan hydrochloride, isotretinoin, methotrexate, methotrexate sodium, pipobroman, vincristine, vincristine sulfate

Genes related to leukemia, acute promyelocytic, pml/rara type according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	PML	promyelocytic leukemia	11.1	Disorders