MCID: LKR001
MIFTS: 29

Leukorrhea malady

Categories: Reproductive diseases

Aliases & Classifications for Leukorrhea

Aliases & Descriptions for Leukorrhea:

Name: Leukorrhea 12 42 14
Discharge - Leukorrhea 12
Leukorrhea of Vagina 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3766
ICD10 33 N89.8
MeSH 42 D007973
NCIt 47 C34775
UMLS 69 C0023533

Summaries for Leukorrhea

MalaCards based summary : Leukorrhea, also known as discharge - leukorrhea, is related to vaginitis and cervicitis. An important gene associated with Leukorrhea is TNNT1 (Troponin T1, Slow Skeletal Type), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and Toxoplasmosis. The drugs Metronidazole and Clindamycin have been mentioned in the context of this disorder. Affiliated tissues include cervix, testes and uterus.

Wikipedia : 71 Leukorrhea or (leucorrhoea British English) is a thick, whitish or yellowish vaginal discharge. There... more...

Related Diseases for Leukorrhea

Diseases related to Leukorrhea via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 vaginitis 10.0
2 cervicitis 10.0
3 bacterial vaginosis 10.0
4 collagenous colitis 9.8 CD79A PTGS2
5 childhood intracortical osteosarcoma 9.8 CD79A PTGS2
6 vaginal discharge 9.7
7 salpingitis 9.7
8 endocervicitis 9.7
9 bone angioendothelial sarcoma 9.7 CD79A PTGS2
10 chordoid glioma 9.2 CD79A DYNC1I2 NFKBIA PTGS2 TNNT1

Graphical network of the top 20 diseases related to Leukorrhea:



Diseases related to Leukorrhea

Symptoms & Phenotypes for Leukorrhea

Drugs & Therapeutics for Leukorrhea

Drugs for Leukorrhea (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metronidazole Approved Phase 4,Phase 3 443-48-1 4173
2
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
3 Anti-Bacterial Agents Phase 4,Phase 3
4 Anti-Infective Agents Phase 4,Phase 3
5 Antiparasitic Agents Phase 4,Phase 3
6 Antiprotozoal Agents Phase 4,Phase 3
7 Clindamycin palmitate Phase 4
8 Clindamycin phosphate Phase 4
9
Neomycin Approved, Vet_approved Phase 3 1404-04-2 8378
10
Fluconazole Approved Phase 3 86386-73-4 3365
11
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
12
Josamycin Approved Phase 3 16846-24-5 5282165
13
Nystatin Approved, Vet_approved Phase 3 1400-61-9 11953884
14 Polymyxin B Phase 3
15 Secnidazole Phase 3
16 Steroid Synthesis Inhibitors Phase 3
17 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
18 Cytochrome P-450 CYP3A Inhibitors Phase 3
19 Cytochrome P-450 Enzyme Inhibitors Phase 3
20 Hormone Antagonists Phase 3
21 Hormones Phase 3
22 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
23 Polymyxins Phase 3
24 Antifungal Agents Phase 3
25 Ionophores Phase 3
26 Antibiotics, Antitubercular Phase 3

Interventional clinical trials:


id Name Status NCT ID Phase
1 The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet Treatment of Bacterial Vaginosis Recruiting NCT03080740 Phase 4
2 Safety and Clinical and Microbiological Efficacy of the Combination of Fluconazole and Secnidazole for the Treatment of Symptomatic Vaginal Discharge Completed NCT02111629 Phase 3
3 Assessment of the Efficacy of POLYGYNAX® in the Empirical Treatment of Infectious Vaginitis Completed NCT02515656 Phase 3
4 Reduction of Spontaneous Prematurity by Antibiotic Treatment (Josamycin) Completed NCT00718705 Phase 3
5 A Pilot Study to Evaluate the Safety and Activities of EW02 in Reducing Neutropenia Caused by Chemotherapy Unknown status NCT00555516 Phase 1, Phase 2
6 Cryotherapy for Human Papillomavirus Clearance in Biopsy-confirmed Cervical Low-grade Squamous Intraepithelial Lesions Terminated NCT00566579

Search NIH Clinical Center for Leukorrhea

Cochrane evidence based reviews: leukorrhea

Genetic Tests for Leukorrhea

Anatomical Context for Leukorrhea

MalaCards organs/tissues related to Leukorrhea:

39
Cervix, Testes, Uterus

Publications for Leukorrhea

Articles related to Leukorrhea:

(show all 38)
id Title Authors Year
1
Perceptions and Knowledge about Leukorrhea in a Slum Dwelling South Asian Community. ( 24971133 )
2014
2
Correlation of leukorrhea and Trichomonas vaginalis infection. ( 23678058 )
2013
3
Cervical leukorrhea is correlated with bacterial vaginosis. ( 21315345 )
2011
4
By the way, doctor. I'm a healthy 62-year-old. In the past three months, I've developed a vaginal discharge and discomfort. tests for vaginal infections have been negative. I've tried douching and sitz baths. I started using vaginal estrogen (Premarin) cream about two months ago. Nothing helps. I'd appreciate your thoughts on this problem, which my gynecologist calls "chronic leukorrhea.". ( 20217961 )
2010
5
Patient 60 years old with post menopausal metrorrhagia and fetid leukorrhea. ( 19617161 )
2008
6
Combination of bacterial vaginosis and leukorrhea as a predictor of cervical chlamydial or gonococcal infection. ( 12039120 )
2002
7
Leukorrhea and bacterial vaginosis as in-office predictors of cervical infection in high-risk women. ( 12383553 )
2002
8
Cultural and biomedical meanings of the complaint of leukorrhea in South Asian women. ( 11348516 )
2001
9
Bacteriological study of leukorrhea. ( 6813525 )
1982
10
Corynebacterium vaginale (Haemophilus vaginalis) in women with leukorrhea. ( 984128 )
1976
11
LEUKORRHEA IN THE ADULT FEMALE. ( 14211262 )
1965
12
Hemophilus vaginalis in leukorrhea: incidence, diagnosis, and treatment. ( 13993388 )
1963
13
New relief for leukorrhea. ( 14464077 )
1962
14
Leukorrhea and vaginitis. ( 14494891 )
1961
15
Uterus didelphys presenting as leukorrhea. Report of a case. ( 13695052 )
1961
16
LEUKORRHEA during childhood. ( 13627071 )
1959
17
Leukorrhea; its causes and a new vaginal classification. ( 13668938 )
1959
18
Leukorrhea. ( 13394855 )
1957
19
[Gynecological experiences with albothyl; contribution to the colposcopic & cytological control of leukorrhea & erosion of the cervix]. ( 13493441 )
1957
20
Endamoeba histolytica in leukorrhea and salpingitis. ( 13444376 )
1957
21
Leukorrhea; therapy in the office management. ( 13333451 )
1956
22
Leukorrhea; causes and management. ( 13286644 )
1956
23
The cytolytic changes of the vaginal epithelial cells and the leukorrhea following estrogenic therapy. ( 14388062 )
1955
24
Treatment of leukorrhea with douches and broad spectrum therapy. ( 13268014 )
1955
25
Leukorrhea therapy of 510 cases. ( 14370496 )
1955
26
Psychosomatic leukorrhea; report of a case. ( 13230917 )
1955
27
Acid detergent douche therapy of leukorrhea. ( 13150198 )
1954
28
The office management of leukorrhea. ( 13016857 )
1953
29
Leukorrhea. ( 13085113 )
1953
30
Chlorophyll, studies on the clinical application and its action in the treatment of leukorrhea vaginalis. ( 13004278 )
1952
31
Leukorrhea in general practice; its diagnosis and treatment. ( 12992109 )
1952
32
Chlorophyll; studies on the clinical application and its action in the treatment of leukorrhea vaginalis. ( 13010909 )
1952
33
Leukorrhea of pregnancy; subsequent study of caprokol jelly. ( 15410418 )
1950
34
Leukorrhea, diagnosis and treatment. ( 18152375 )
1949
35
The rational management of leukorrhea. ( 18894219 )
1948
36
Leukorrhea; its causes and treatment. ( 20254969 )
1947
37
Leukorrhea. ( 20255882 )
1947
38
ELECTROTHERMOCAUTERY TREATMENT OF LEUKORRHEA DUE TO ENDOCERVICITIS. ( 18739169 )
1923

Variations for Leukorrhea

Expression for Leukorrhea

Search GEO for disease gene expression data for Leukorrhea.

Pathways for Leukorrhea

GO Terms for Leukorrhea

Sources for Leukorrhea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
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43 MESH via Orphanet
44 MGI
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47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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