MCID: LCN001
MIFTS: 38

Lice Infestation

Categories: Infectious diseases

Aliases & Classifications for Lice Infestation

MalaCards integrated aliases for Lice Infestation:

Name: Lice Infestation 12 14
Mixed Pediculosis 12 69
Lice Infestations 41 69
Pediculosis 12 72
Pediculosis and Phthirus Infection Nos 12
Pediculosis and Phthirus Infestation 12
Pediculosis and Phthirus Infections 12
Pediculosis and Phthirus Infection 12
Mixed Pediculosis Infestation 12
Infestation by Pediculus 12
Pediculosis, Unspecified 12
Infestation by Anoplura 69
Pediculosis + Lice Nos 12
Lice Infestation, Nos 12
Louse Infestation 12

Classifications:



Summaries for Lice Infestation

Disease Ontology : 12 A parasitic ectoparasitic infectious disease that involves infestation of lice, which are blood-feeding ectoparasitic insects of the order Phthiraptera.

MalaCards based summary : Lice Infestation, also known as mixed pediculosis, is related to pthirus pubis infestation and pediculus humanus capitis infestation. An important gene associated with Lice Infestation is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways/superpathways is Cardiac muscle contraction. The drugs Doxycycline and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes.

Wikipedia : 72 Pediculosis is an infestation of lice (blood-feeding ectoparasitic insects of the order Phthiraptera).... more...

Related Diseases for Lice Infestation

Graphical network of the top 20 diseases related to Lice Infestation:



Diseases related to Lice Infestation

Symptoms & Phenotypes for Lice Infestation

Drugs & Therapeutics for Lice Infestation

Drugs for Lice Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 52)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3 564-25-0 54671203
2
Azithromycin Approved Phase 4 83905-01-5 53477736 447043 55185
3 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1
4 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
5 Antimalarials Phase 4,Phase 3
6 Antibiotics, Antitubercular Phase 4
7 Antiprotozoal Agents Phase 4,Phase 3
8 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1
9 Antitubercular Agents Phase 4
10 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
11
Telithromycin Approved Phase 3 191114-48-4 0 5462516
12
Ethanol Approved Phase 3,Phase 2 64-17-5 702
13
Ivermectin Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 70288-86-7 46936176 6474909
14
Malathion Approved, Investigational Phase 3,Phase 2,Phase 1 121-75-5 4004
15
Benzyl alcohol Approved Phase 3,Phase 2 100-51-6 244
16
Metronidazole Approved Phase 3 443-48-1 4173
17
Permethrin Approved, Investigational Phase 3,Phase 2 52645-53-1 40326
18
Menthol Approved Phase 2, Phase 3 2216-51-5 16666
19 Central Nervous System Depressants Phase 3,Phase 2
20 Cholinergic Agents Phase 3,Phase 2,Phase 1
21 Cholinesterase Inhibitors Phase 3,Phase 2,Phase 1
22 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
23 Anesthetics Phase 3,Phase 2
24 Anesthetics, Local Phase 3,Phase 2
25 Peripheral Nervous System Agents Phase 3,Phase 2
26 Anti-Infective Agents, Local Phase 3
27 Dermatologic Agents Phase 3
28 Emollients Phase 3
29 Pulmonary Surfactants Phase 2, Phase 3
30 Rue Nutraceutical Phase 3
31 Neem Nutraceutical Phase 2, Phase 3
32
Estradiol Approved, Investigational, Vet_approved Phase 1 50-28-2 5757
33
Norgestimate Approved, Investigational Phase 1 35189-28-7 6540478
34
Moxifloxacin Approved, Investigational Phase 1 151096-09-2, 354812-41-2 152946
35
Ethinyl Estradiol Approved Phase 1 57-63-6 5991
36 Nucleic Acid Synthesis Inhibitors Phase 1
37 Estradiol valerate Phase 1 979-32-8
38 Fluoroquinolones Phase 1
39 Topoisomerase Inhibitors Phase 1
40 Contraceptive Agents Phase 1
41 Contraceptives, Oral Phase 1
42 Contraceptives, Oral, Combined Phase 1
43 Norgestimate, ethinyl estradiol drug combination Phase 1
44 Estradiol 17 beta-cypionate Phase 1
45 Estradiol 3-benzoate Phase 1
46 Polyestradiol phosphate Phase 1
47
Rifampin Approved 13292-46-1 5381226 5458213
48
Albendazole Approved, Vet_approved 54965-21-8 2082
49 Cytochrome P-450 CYP3A Inducers
50 Anthelmintics

Interventional clinical trials:

(show top 50) (show all 69)

# Name Status NCT ID Phase Drugs
1 Pharmacokinetic (PK) and Tolerance Study of Natroba Topical Suspension in Pediatrics With an Active Head Lice Infestation Completed NCT01660321 Phase 4 spinosad
2 Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application Completed NCT00995124 Phase 4 NeutraLice Lotion;NeutraLice Advance Solution;Moov Head Lice Solution
3 Scrub Typhus Antibiotic Resistance Trial Recruiting NCT03083197 Phase 4 Doxycycline 7 days;Doxycycline 3 days;Azithromycin 3 days
4 A Study to Evaluate the Safety and Efficacy of Product X92001327 vs RID Shampoo in Subjects With Head Lice Unknown status NCT01803581 Phase 3
5 Efficacy and Safety Study for PIOLIN® Shampoo Unknown status NCT01966965 Phase 3 PIOLIN®;NEDAX
6 Controlled Trial: 5-Day Course of Telithromycin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus Unknown status NCT00351182 Phase 3 Telithromycin;Doxycycline
7 Neem Lotion With Combing for Lice Completed NCT02974088 Phase 2, Phase 3
8 P3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02062060 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
9 Ivermectin in the Treatment of Head Lice Completed NCT00819520 Phase 3 ivermectin;malathion
10 A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation Completed NCT01066585 Phase 3 Ivermectin Cream;vehicle control
11 Phase 3 Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation Completed NCT02060903 Phase 3 Abametapir Lotion 0.74% w/w;Vehicle Lotion
12 Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice Completed NCT00963508 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse (Nix Crème)
13 A Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT01068158 Phase 3 0.5% Ivermectin Cream;Placebo control
14 Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice Completed NCT00244439 Phase 3 MALG;Ovide (malathion) lotion 0.05%;Permethrin 1%
15 Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice Completed NCT00927472 Phase 3 Malathion gel 0.5%;Permethrin 1% rinse
16 Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Completed NCT00545753 Phase 3 Spinosad;Spinosad;Permethrin 1%
17 A Randomised, Assessor-Blind, Comparative Efficacy Clinical Trial of 3 Pediculicides. Completed NCT00381082 Phase 2, Phase 3 1) MOOV Head Lice Treatment (Ego Pharmaceutical).;Banlice Mousse Aerosol (Pfizer, Australia);3) KP24 Medicated Foam (Nelson Laboratories)
18 A Clinical Endpoint Bioequivalence Study to Assess Efficacy and Safety of Ivermectin 0.5% Lotion in the Treatment of Head Lice Completed NCT03337490 Phase 3 Ivermectin 0.5% Topical Application Lotion;Ivermectin 0.5% Topical Application Lotion [SKLICE];Placebo 0% Lotion
19 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice Completed NCT00301340 Phase 3 5% Lice Asphyxiator lotion - Summers Laboratories, Inc.
20 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice Completed NCT00479310 Phase 3 Summers 5% L.A.
21 Safety and Tolerability of a Novel Malathion Formulation in Children Age 6-24 Months With Head Lice Completed NCT00752973 Phase 2, Phase 3 MALG (malathion) Treatment
22 Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Completed NCT00545168 Phase 3 Spinosad;Spinosad;Permethrin 1%
23 Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice. Completed NCT00301327 Phase 3 Summers 5% L.A.
24 Bioequivalence Study for Benzyl Alcohol Lotion 5%. Completed NCT02624843 Phase 3 Benzyl Alcohol Lotion 5%;Ulesfia (benzyl alcohol lotion) 5%;Placebo
25 Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1% Completed NCT02236403 Phase 3 Ivermectin 0.1% Metronidazole 1%
26 Clinical Endpoint Study of Ivermectin 0.5% Lotion Recruiting NCT03301649 Phase 3 Ivermectin Lotion 0.5%;Placebo/Vehicle Lotion
27 Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands Active, not recruiting NCT03236168 Phase 3 Ivermectin;Permethrin 5%;Malathion Shampoo 0.5%
28 Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies Not yet recruiting NCT02841215 Phase 3 Ivermectin 200 µg/kg;Ivermectin 400 µg/kg
29 Two Treatment Regimens of Cocamide DEA Lotion for Head Lice Terminated NCT02499549 Phase 2, Phase 3 cocamide diethanolamine
30 Cocamide DEA vs Permethrin for Head Lice Terminated NCT02500524 Phase 3 Cocamide diethanolamine;Permethrin
31 Pediatric Head Lice Study Product Comparison Completed NCT02213055 Phase 2 LICEMD;Standard Head lice product
32 Safety and PK Study of Ha44 Gel Under Maximal Use Conditions for Treatment of Head Lice Infestation Completed NCT01907490 Phase 2 Ha44 Gel
33 Ovicidal Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation Completed NCT02097485 Phase 2 Abametapir Lotion 0.74% w/w;Vehicle Lotion
34 An Efficacy and Safety Study of Ha44 Gel Administered Topically for the Treatment of Head Lice Infestation Completed NCT01336647 Phase 2 Group A - Low-Dose Ha44 0.37% w/w;Group B - High Dose Ha44 Gel 0.74% w/w;Group C - Placebo
35 A Study Evaluating the Safety and Efficacy of BGC20-0582 Lice Treatment Gel for Head Lice Infestation Completed NCT00528021 Phase 2 Placebo;BGC20-0582
36 Dose Ranging Study of Ivermectin Treatment Conditioner in Subjects With Head Lice Infestation Completed NCT00857948 Phase 2 ivermectin treatment conditioner;Placebo, vehicle control
37 A Dose Ranging Study of Different Strengths of Spinosad Topical Creme in Subjects With Pediculosis Capitis Completed NCT00311779 Phase 2 Spinosad Creme Rinse
38 A Safety and Efficacy Pilot Study Comparing NatrOVA Creme Rinse 1% and NIX Creme Rinse Completed NCT00857935 Phase 2 NatrOVA Creme Rinse - 1%;NIX Creme Rinse - 1% permethrin
39 A Pediatric Safety and Pharmacokinetics Study of Ha44 Gel Administered Topically for Treatment of Head Lice Infestation Completed NCT02010333 Phase 2 Ha44 Gel 0.74% w/w
40 A Pilot Dose Ranging Study of Spinosad Creme Rinse Completed NCT00858481 Phase 2 Spinosad Creme Rinse - Vehicle Control;Spinosad Creme Rinse;Spinosad Creme Rinse;Spinosad Creme Rinse
41 Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT00994422 Phase 2 Ivermectin cream;vehicle control
42 Efficacy and Safety of Topical 0.5% Ivermectin Lotion for the Treatment of Head Lice Infestation in Filipinos Recruiting NCT03286101 Phase 2 0.5% Ivermectin lotion;Vehicle
43 Safety and Tolerability of a Novel Malathion Formulation in Infants and Toddlers With Head Lice Terminated NCT00291057 Phase 2 MALG
44 Pharmacokinetics of Malathion Gel 0.5% and Malathion 0.5% Lotion (Ovide) in Patients With Head Lice Completed NCT00927407 Phase 1 Malathion gel 0.5%;Malathion lotion 0.5%
45 A Pharmacokinetics (PK) Study in Lice Infested Children 6 Months to 3 Years of Age Completed NCT00988533 Phase 1 0.5% Ivermectin Cream
46 A Bioequivalence Study, Comparing Two Formulations of Ivermectin Lotion, 0.5% Completed NCT03257943 Phase 1 Ivermectin Lotion, 0.5%;SKLICE (ivermectin) Lotion, 0.5%;Vehicle of the Test product
47 A Pharmacokinetic (PK) Study of NatrOVA Topical Creme (1%) in Pediatric Subjects 6 to 24 Months of Age Completed NCT00410709 Phase 1 NatrOVA Creme Rinse (1%)
48 Phototoxicity Potential of NatrOVA Creme Rinse - 1% Completed NCT00591331 Phase 1 Spinosad (the active ingredient in NatrOVA);placebo
49 NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers Completed NCT00605956 Phase 1 NatrOVA Creme Rinse - 1%;NatrOVA Creme Rinse Vehicle Only;Blank Patch
50 Dermal Safety Study to Evaluate the Sensitizing Potential of Abametapir Lotion Completed NCT02062073 Phase 1 Abametapir Lotion 0.74% w/w

Search NIH Clinical Center for Lice Infestation

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: lice infestations

Genetic Tests for Lice Infestation

Anatomical Context for Lice Infestation

MalaCards organs/tissues related to Lice Infestation:

38
Testes

Publications for Lice Infestation

Articles related to Lice Infestation:

(show top 50) (show all 64)
# Title Authors Year
1
The efficacy of Australian essential oils for the treatment of head lice infestation in children: A randomised controlled trial. ( 28266704 )
2017
2
Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. ( 28072852 )
2017
3
Control of lice infestation in horses using a 10 mg/mL deltamethrin topical application. ( 28649361 )
2017
4
Correction: Efficacy of Peer Education for Adopting Preventive Behaviors against Head Lice Infestation in Female Elementary School Students: A Randomised Controlled Trial. ( 28926612 )
2017
5
Sea lice infestation levels decrease with deeper 'snorkel' barriers in Atlantic salmon sea-cages. ( 28247541 )
2017
6
Prevalence of head lice infestation and pediculicidal effect of permethrine shampoo in primary school girls in a low-income area in southeast of Iran. ( 28738799 )
2017
7
Assessment of oral ivermectin versus shampoo in the treatment of pediculosis (head lice infestation) in rural areas of Sine-Saloum, Senegal. ( 27866866 )
2016
8
Space-time cluster analysis of sea lice infestation (Caligus clemensi and Lepeophtheirus salmonis) on wild juvenile Pacific salmon in the Broughton Archipelago of Canada. ( 25869117 )
2015
9
Prevalence of Head Lice Infestation and Its Associated Factors among Primary School Students in Iran: A Systematic Review and Meta-analysis. ( 26835244 )
2015
10
Severe iron deficiency anaemia associated with heavy lice infestation in a young woman. ( 26542960 )
2015
11
A Study of Head Lice Infestation (Pediculosis Capitis) among Primary School Students in the Villages of Abadan in 2012. ( 25349862 )
2014
12
Evaluation of a health education program for head lice infestation in female primary school students in Chabahar City, Iran. ( 23273236 )
2013
13
PREVALENCE OF HEAD LICE INFESTATION IN PRIMARY SCHOOL CHILDREN IN PORT HARCOURT. ( 26866185 )
2013
14
Efficacy and Safety of Dimeticone in the Treatment of Lice Infestation through Prophylaxis of Classmates. ( 24427749 )
2013
15
Assessment of the safety and efficacy of three concentrations of topical ivermectin lotion as a treatment for head lice infestation. ( 23278618 )
2013
16
Effect of households' social networks on lice infestation among vulnerable Mexican children: a qualitative comparative analysis. ( 23751254 )
2013
17
PREVALENCE OF HEAD LICE INFESTATION IN PRIMARY SCHOOL CHILDREN IN PORT HARCOURT. ( 26866114 )
2013
18
Cross-sectional study of cattle lice infestation in the region of Nabeul in north-east Tunisia. ( 24761739 )
2013
19
Head lice infestation in schoolchildren and related factors in Mafraq governorate, Jordan. ( 22250625 )
2012
20
Lice infestations and scabies. ( 22991888 )
2012
21
Severe head lice infestation in an Andean mummy of Arica, Chile. ( 22010860 )
2012
22
What's bugging you? An update on the treatment of head lice infestation. ( 20688849 )
2011
23
Hair characteristics and lice infestation. Data from schoolchildren in Greece. ( 20497289 )
2011
24
Parental attitudes towards head lice infestation in Greece. ( 21595662 )
2011
25
Spinosad for treatment of head lice infestation. ( 21750308 )
2011
26
Oral Ivermectin is more effective than topical malathion in difficult-to-treat head lice infestation. ( 21482534 )
2011
27
Severe iron deficiency anemia and lice infestation. ( 20656443 )
2011
28
Epidemiology of head lice infestation in primary school pupils, in khajeh city, East azerbaijan province, iran. ( 22808387 )
2010
29
Seasonal fluctuations of head lice infestation in Germany. ( 19015879 )
2009
30
Pesticide exposure resulting from treatment of lice infestation in school-aged children in Georgia. ( 18947873 )
2009
31
The treatment and prevention of head lice infestation. ( 19999418 )
2009
32
Self-diagnosis of active head lice infestation by individuals from an impoverished community: high sensitivity and specificity. ( 18488093 )
2008
33
Use of a formulation containing imidacloprid and moxidectin in the treatment of lice infestation in guinea pigs. ( 18477336 )
2008
34
Assessing a patient for lice infestation. ( 18580642 )
2008
35
Changes in epidemiological patterns of sea lice infestation on farmed Atlantic salmon, Salmo salar L., in Scotland between 1996 and 2006. ( 18353017 )
2008
36
An overview of head lice infestation in neurosurgical patients. ( 18026036 )
2007
37
A downturn in the incidence of head lice infestation? ( 17550575 )
2007
38
Lice infestation and lice control remedies in the Ukraine. ( 17114740 )
2006
39
Prevalence and associated factors of head lice infestation among primary schoolchildren in Kelantan, Malaysia. ( 17120976 )
2006
40
Correct diagnosis of current head lice infestation made by affected individuals from a hyperendemic area. ( 17184249 )
2006
41
The prevalence of head lice infestation in school children in izmir, Turkey. ( 16060882 )
2005
42
American Academy of Pediatrics guidelines for the prevention and treatment of head lice infestation. ( 15515631 )
2004
43
Relationship between lice infestation and leather damage in cattle. ( 12974336 )
2003
44
A survey on head lice infestation in Korea (2001) and the therapeutic efficacy of oral trimethoprim/sulfamethoxazole adding to lindane shampoo. ( 12666731 )
2003
45
A longitudinal study of a natural lice infestation in growing cattle over two winter periods. ( 12623210 )
2003
46
A longitudinal study of a natural lice infestation in growing cattle over two winter periods. ( 14519329 )
2003
47
Field trials in Norway with SLICE (0.2% emamectin benzoate) for the oral treatment of sea lice infestation in farmed Atlantic salmon Salmo salar. ( 12152902 )
2002
48
Head lice infestation: single drug versus combination therapy. ( 11731678 )
2001
49
Head lice infestation: single drug versus combination therapy with one percent permethrin and trimethoprim/sulfamethoxazole. ( 11230611 )
2001
50
Head lice infestation: bug busting vs. traditional treatment. ( 11822849 )
2001

Variations for Lice Infestation

Expression for Lice Infestation

Search GEO for disease gene expression data for Lice Infestation.

Pathways for Lice Infestation

Pathways related to Lice Infestation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.52 MT-CO1 MT-CYB

GO Terms for Lice Infestation

Cellular components related to Lice Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 respiratory chain GO:0070469 8.96 MT-CO1 MT-CYB
2 mitochondrial respiratory chain complex III GO:0005750 8.62 MT-CO1 MT-CYB

Biological processes related to Lice Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell shape GO:0008360 9.16 ARHGAP18 KDR
2 hydrogen ion transmembrane transport GO:1902600 8.96 MT-CO1 MT-CYB
3 response to copper ion GO:0046688 8.62 MT-CO1 MT-CYB

Molecular functions related to Lice Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 electron transfer activity GO:0009055 8.62 MT-CO1 MT-CYB

Sources for Lice Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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