MCID: LCH014
MIFTS: 30

Lichen Amyloidosis malady

Categories: Skin diseases, Rare diseases

Aliases & Classifications for Lichen Amyloidosis

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Sources:
65UMLS, 51Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Lichen Amyloidosis:

Name: Lichen Amyloidosis 51
Amyloidosis, Primary Cutaneous 65
 
Lichen Amyloidosus 51
Amyloid Lichen 51

Classifications:

Orphanet: 51 
Rare skin diseases


External Ids:

Orphanet51 49804
ICD10 via Orphanet28 L99.0*, E85.4+
UMLS65 C0268397

Summaries for Lichen Amyloidosis

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MalaCards based summary: Lichen Amyloidosis, also known as amyloidosis, primary cutaneous, is related to primary cutaneous amyloidosis and amyloidosis, primary localized cutaneous, 1, and has symptoms including abnormality of skin pigmentation, lichenification and pruritus. An important gene associated with Lichen Amyloidosis is IL31RA (Interleukin 31 Receptor A), and among its related pathways is Immune System. Affiliated tissues include skin, thyroid and prostate.

Related Diseases for Lichen Amyloidosis

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Graphical network of the top 20 diseases related to Lichen Amyloidosis:



Diseases related to lichen amyloidosis

Symptoms for Lichen Amyloidosis

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Symptoms:

 51
  • lichen
  • follicular/erythematous/edematous papules/milium
  • abnormal pigmentary skin changes/skin pigmentation anomalies
  • pruritus/itching
  • neoplasms/tumors
  • multiple myeloma

HPO human phenotypes related to Lichen Amyloidosis:

id Description Frequency HPO Source Accession
1 abnormality of skin pigmentation hallmark (90%) HP:0001000
2 lichenification hallmark (90%) HP:0100725
3 pruritus typical (50%) HP:0000989
4 multiple myeloma occasional (7.5%) HP:0006775

UMLS symptoms related to Lichen Amyloidosis:


skin symptom, abnormal granulation tissue, osler's node, umbilical discharge

Drugs & Therapeutics for Lichen Amyloidosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Lichen Amyloidosis

Genetic Tests for Lichen Amyloidosis

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Anatomical Context for Lichen Amyloidosis

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MalaCards organs/tissues related to Lichen Amyloidosis:

33
Skin, Thyroid, Prostate, Testes, Liver, Breast, Heart

Animal Models for Lichen Amyloidosis or affiliated genes

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Publications for Lichen Amyloidosis

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Articles related to Lichen Amyloidosis:

(show all 50)
idTitleAuthorsYear
1
Cutaneous lichen amyloidosis in multiple endocrine neoplasia. (26813904)
2016
2
MEN 2A-related cutaneous lichen amyloidosis: report of three kindred and systematic literature review of clinical, biochemical and molecular characteristics. (26920351)
2016
3
Bullous variant of familial biphasic lichen amyloidosis: a unique combination of three rare presentations. (25657431)
2015
4
THE AUTOIMMUNE CONSTELLATION IN LICHEN AMYLOIDOSIS. (26793847)
2015
5
Vesicular lesions in lichen amyloidosis. (26374661)
2015
6
Fractional 1,550nm Ytterbium/Erbium fiber laser in the treatment of lichen amyloidosis: Clinical and histological study. (25771782)
2015
7
Vesicular lesions in lichen amyloidosis. (26515863)
2015
8
Successful treatment of lichen amyloidosis using capsaicin 8% patch. (25904403)
2015
9
Itch in familial lichen amyloidosis: effective treatment with amitriptyline in two cases. (24502303)
2014
10
Successful treatment of lichen amyloidosis using a CO2 surgical laser. (24703261)
2014
11
Response to oral acitretin in lichen amyloidosis. (25593815)
2014
12
Bullous pemphigoid clinically presenting as lichen amyloidosis. (25382517)
2014
13
A Th2 Cytokine Interleukin 31 Signature in a Case of Sporadic Lichen Amyloidosis. (24573820)
2014
14
Rare manifestation of multiple endocrine neoplasia type 2A & cutaneous lichen amyloidosis in a family with RET gene mutation. (25027091)
2014
15
Generalized lichen amyloidosis and hyperthyroidism: coincidence or association. (24278086)
2013
16
Asymptomatic conchal papules. Lichen amyloidosis of the auricular concha. (23619461)
2013
17
Lichen amyloidosis. (24130236)
2013
18
A generalized, non-pruritic variant of lichen amyloidosis: a case report and a brief review. (23919033)
2013
19
Primary cutaneous lichen amyloidosis of the external auditory canal, possibly due to scratching with a metal nail head for severe pruritus. (24201228)
2013
20
Satisfactory response to narrowband UV-B therapy in generalized lichen amyloidosis. (23084256)
2013
21
'Shiny white streaks' in lichen amyloidosis: a clue to diagnosis. (23157777)
2012
22
Lichen Amyloidosis: Novel Treatment with Fractional Ablative 2,940 nm Erbium: YAG Laser Treatment. (23060710)
2012
23
Dermacase. Can you identify this condition? Lichen amyloidosis. (23152462)
2012
24
Lichen amyloidosis in a dark skinned patient. (20197753)
2010
25
Lichen amyloidosis of the auricular concha: successful treatment with electrodesiccation. (19284460)
2009
26
Successful treatment of therapy-resistant pruritus in lichen amyloidosis with menthol. (19734984)
2009
27
A case of atopic dermatitis-associated lichen amyloidosis successfully treated with oral cyclosporine and narrow band UVB therapy in succession. (19954395)
2009
28
Familial medullary thyroid carcinoma associated with cutaneous lichen amyloidosis. (19445625)
2009
29
A case of membranous lipodystrophy observed in lichen amyloidosis. (20523780)
2009
30
Pruritic patches on the back and papules on the legs. Primary localized cutaneous amyloidosis (PLCA) (cutaneous lichen amyloidosis and macular amyloidosis). (17310008)
2007
31
Multiple endocrine neoplasia type 2A/localized cutaneous lichen amyloidosis associated with malignant pheochromocytoma and ganglioneuroma. (16277170)
2005
32
Visual vignette. Multiple endocrine neoplasia type 2A (MEN2A) associated with cutaneous lichen amyloidosis. (14758805)
2003
33
Frequent association between MEN 2A and cutaneous lichen amyloidosis. (12864791)
2003
34
Early onset of medullary thyroid carcinoma in a kindred with multiple endocrine neoplasia type iia associated with cutaneous lichen amyloidosis. (11939755)
2002
35
Cutaneous lichen amyloidosis in multiple endocrine neoplasia type 2A. (12593731)
2002
36
Treatment of lichen amyloidosis (LA) and disseminated superficial porokeratosis (DSP) with frequency-doubled Q-switched Nd:YAG laser. (11050503)
2000
37
Lichen amyloidosis, ankylosing spondylitis and autoimmune thyroiditis: coincidence or association? (10972101)
2000
38
A Cys634Gly substitution of the RET proto-oncogene in a family with recurrence of multiple endocrine neoplasia type 2A and cutaneous lichen amyloidosis. (9111993)
1997
39
RET mutation screening in familial cutaneous lichen amyloidosis and in skin amyloidosis associated with multiple endocrine neoplasia. (8757765)
1996
40
Identification of the Cys634-->Tyr mutation of the RET proto-oncogene in a pedigree with multiple endocrine neoplasia type 2A and localized cutaneous lichen amyloidosis. (7914213)
1994
41
Clinicopathologic and immunohistochemical studies on lichen amyloidosis and macular amyloidosis. (7527208)
1994
42
Multiple endocrine neoplasia type 2A and cutaneous lichen amyloidosis: description of a new family. (8099921)
1993
43
Cutaneous lesion associated with multiple endocrine neoplasia type 2A: lichen amyloidosis or notalgia paresthetica? (1362414)
1992
44
Sipple syndrome with lichen amyloidosis as a paracrinopathy. (1352941)
1992
45
Lichen amyloidosis in Alagille syndrome. (1929477)
1991
46
Sipple syndrome with lichen amyloidosis as a paracrinopathy: pleiotropy, heterogeneity, or a contiguous gene? (1686438)
1991
47
Cutaneous lichen amyloidosis and familial medullary thyroid carcinoma. (1969255)
1990
48
Cutaneous lichen amyloidosis associated with multiple endocrine neoplasia type 2A. (2576949)
1989
49
Familial cutaneous lichen amyloidosis in association with multiple endocrine neoplasia type 2A: a new variant. (2576950)
1989
50
Multiple endocrine neoplasia type 2a associated with cutaneous lichen amyloidosis. (2573304)
1989

Variations for Lichen Amyloidosis

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Expression for genes affiliated with Lichen Amyloidosis

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Search GEO for disease gene expression data for Lichen Amyloidosis.

Pathways for genes affiliated with Lichen Amyloidosis

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Pathways related to Lichen Amyloidosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
8.0IL31, IL31RA, OSMR, RET

GO Terms for genes affiliated with Lichen Amyloidosis

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Biological processes related to Lichen Amyloidosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription, DNA-templatedGO:00458939.1IL31RA, RET

Sources for Lichen Amyloidosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet