Aliases & Classifications for Lichen Planus

MalaCards integrated aliases for Lichen Planus:

Name: Lichen Planus 12 52 42 14 69
Lichen, Ruber Planus 12
Lichen Ruber Planus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9201
ICD10 33 L43 L43.9
ICD9CM 35 697.0
MeSH 42 D008010
NCIt 47 C3189
UMLS 69 C0023646

Summaries for Lichen Planus

Disease Ontology : 12 A lichen disease that is located in skin, located in tongue or located in oral mucosa, which presents itself in the form of papules, lesions or rashes.

MalaCards based summary : Lichen Planus, also known as lichen, ruber planus, is related to scabies and dysphagia, and has symptoms including pruritus An important gene associated with Lichen Planus is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways/superpathways are Allograft rejection and Influenza A. The drugs Benzocaine and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include skin, tongue and t cells, and related phenotypes are Increased gamma-H2AX phosphorylation and digestive/alimentary

Wikipedia : 72 Lichen planus (LP) is a disease characterized by itchy reddish-purple polygon-shaped skin lesions on the... more...

Related Diseases for Lichen Planus

Diseases in the Lichen Planus family:

Rare Lichen Planus

Diseases related to Lichen Planus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 337)
id Related Disease Score Top Affiliating Genes
1 scabies 30.8 ICAM1 IFNG TNF
2 dysphagia 30.7 ICAM1 IFNG TNF
3 acral lentiginous melanoma 30.5 IFNG TNF TP53
4 lymphoma 29.9 COL17A1 DST IFNG IL4 TLR9 TNF
5 burn scar 29.8 CXCR3 DEFB4A GZMB IFNG TNF
6 rheumatoid arthritis 29.7 ICAM1 IFNG IL4 ITGAL TNF
7 systemic lupus erythematosus 29.6 CXCR3 ICAM1 IFNG IL4 TLR9 TNF
8 asthma 29.3 FLG ICAM1 IFNG IL4 TLR9 TNF
9 tinea nigra 28.7 FLG IVL KRT10 KRT16 TNF
10 actinic lichen planus 12.6
11 lichen planus pigmentosus 12.6
12 lichen planus pemphigoides 12.6
13 linear lichen planus 12.6
14 oral lichen planus 12.5
15 atrophic lichen planus 12.5
16 annular lichen planus 12.5
17 annular atrophic lichen planus 12.5
18 bullous lichen planus 12.3
19 rare lichen planus 12.3
20 lichen planopilaris 12.0
21 vulvovaginal gingival syndrome 11.6
22 graham-little-piccardi-lassueur syndrome 11.3
23 amyloidosis, primary localized cutaneous, 1 11.0
24 amyloidosis, primary localized cutaneous, 2 11.0
25 nail disorder, nonsyndromic congenital, 1 11.0
26 bier spots 11.0
27 myoclonic astatic epilepsy 10.9 IFNG IL4
28 oral erosive lichen 10.9
29 acute ackee fruit intoxication 10.9 IL4 TNF
30 eye accommodation disease 10.9 IFNG IL4
31 acute cholinergic dysautonomia 10.8 TNF TP53
32 sternal cleft 10.8 IFNG TNF
33 von economo's disease 10.8 GZMB IFNG
34 ligneous conjunctivitis 10.8 COL17A1 DST
35 atrichia with papular lesions 10.8 ICAM1 IFNG TNF
36 sparse hair ptosis mental retardation 10.8 IFNG TNF TP53
37 autoimmune polyglandular syndrome type 3 10.8 IFNG TNF
38 conduct disorder 10.8 ICAM1 IFNG TNF
39 lymphocytic colitis 10.8 IFNG IL4 TNF
40 early-onset zonular cataract 10.8 IFNG IL4 TNF
41 hypospadias 10.8 ICAM1 IFNG TNF
42 louping ill 10.8 ICAM1 IFNG TNF
43 penis agenesis 10.8 COL17A1 DST
44 limb-body wall complex 10.7 GZMB TNF TP53
45 orbital osteomyelitis 10.7 IFNG IL4 TNF
46 abnormal retinal correspondence 10.7 IFNG IL4 TNF
47 esophagus melanoma 10.7 IFNG IL4 TNF
48 acute contagious conjunctivitis 10.7 ICAM1 IFNG IL4
49 basidiobolomycosis 10.7 IL4 TNF
50 status epilepticus 10.7 IFNG IL4 TNF

Graphical network of the top 20 diseases related to Lichen Planus:



Diseases related to Lichen Planus

Symptoms & Phenotypes for Lichen Planus

UMLS symptoms related to Lichen Planus:


pruritus

GenomeRNAi Phenotypes related to Lichen Planus according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased gamma-H2AX phosphorylation GR00053-A 9.28 KRT10 KRT13 MX1 COL17A1 CXCL9 CXCR3

MGI Mouse Phenotypes related to Lichen Planus:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.23 TNF TP53 DSG3 ICAM1 IFNG IL4

Drugs & Therapeutics for Lichen Planus

Drugs for Lichen Planus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 128)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
2
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 124-94-7 31307
3
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2 378-44-9 9782
4
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2 137071-32-0 6447131 17753757
5
Tacrolimus Approved, Investigational Phase 4,Phase 2 104987-11-3 445643 439492
6
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
7
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Early Phase 1 22916-47-8 4189
9 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1
10
Chitosan Approved, Nutraceutical Phase 4 9012-76-4 71853
11
Glucosamine Approved, Nutraceutical Phase 4 3416-24-8 439213
12
Lycopene Approved, Nutraceutical Phase 4,Phase 2 502-65-8 446925
13
Lactitol Investigational Phase 4 585-86-4 3871
14 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
15 glucocorticoids Phase 4,Phase 3,Phase 2,Early Phase 1
16 Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
17 Hormones Phase 4,Phase 3,Phase 2,Early Phase 1
18 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
19 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Early Phase 1
20 triamcinolone acetonide Phase 4,Phase 3,Phase 2,Early Phase 1
21 Triamcinolone diacetate Phase 4,Phase 3,Phase 2,Early Phase 1
22 Triamcinolone hexacetonide Phase 4,Phase 3,Phase 2,Early Phase 1
23 Antiemetics Phase 4,Phase 3,Phase 2,Early Phase 1
24 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Early Phase 1
25 Antioxidants Phase 4,Phase 3,Phase 2,Phase 1
26 Autonomic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
27 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Early Phase 1
28 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Early Phase 1
29 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
30 Analgesics Phase 4,Phase 3,Phase 2
31 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
32 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
33 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2
34 Antirheumatic Agents Phase 4,Phase 3,Phase 2
35 Betamethasone benzoate Phase 4,Phase 3,Phase 2
36 Betamethasone sodium phosphate Phase 4,Phase 3,Phase 2
37 Betamethasone Valerate Phase 4,Phase 3,Phase 2 2152-44-5
38 Betamethasone-17,21-dipropionate Phase 4,Phase 3,Phase 2
39 Calcineurin Inhibitors Phase 4,Phase 3,Phase 2
40 Dermatologic Agents Phase 4,Phase 2,Phase 3,Early Phase 1
41 Respiratory System Agents Phase 4,Phase 3,Phase 2
42 Carotenoids Phase 4,Phase 2
43 Methylprednisolone acetate Phase 4,Phase 2
44 Methylprednisolone Hemisuccinate Phase 4,Phase 2
45 Neuroprotective Agents Phase 4
46 Prednisolone acetate Phase 4,Phase 2
47 Prednisolone hemisuccinate Phase 4,Phase 2
48 Prednisolone phosphate Phase 4,Phase 2
49 Radiation-Protective Agents Phase 4,Phase 2
50 Antifungal Agents Phase 4,Phase 3,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 63)

id Name Status NCT ID Phase Drugs
1 Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planus Completed NCT02858297 Phase 4 Glucosamine sulfate;triamcinolone acetonide
2 A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus Completed NCT02587117 Phase 4 lycopene;Prednisolone
3 Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planus Completed NCT02443311 Phase 4 Pimecrolimus 1% cream;Betamethasone 17-valerate 0.1% cream
4 The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus Unknown status NCT01083420 Phase 3 Minocycline;Dexamethasone
5 Treatment of Female Genital Erosive Lichen Planus(GELP) With Hexaminolevulinate PDT Unknown status NCT01282515 Phase 2, Phase 3 clobetasolpropionate;hexaminolevulinate
6 Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus Completed NCT02329600 Phase 3 green tea tablets (Green tea extract 5:1) 200 mg;Triamcinolone Acetonide
7 Efficacy of Elidel Cream on Erosive Oral Lichen Planus Completed NCT00130572 Phase 3 Pimecrolimus
8 Chamaemelum Nobile 2% Versus Placebo Topic Gel to Treat Oral Lichen Planus Completed NCT02421770 Phase 3
9 Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen Terminated NCT01061853 Phase 3 TOPICAL SIROLIMUS (RAPAMUNE*);TOPICAL BETAMETHASONE 0.05%
10 A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus Unknown status NCT01524744 Phase 2 Pimecrolimus ointment;Adcortyl
11 Pilot Study of Apremilast (CC-10004) in the Treatment of Moderate to Severe Lichen Planus Unknown status NCT01041625 Phase 2 Apremilast (CC-10004)
12 Lichen Planus Mucosae at USZ, Efficacy of Oral Alitretinoin Unknown status NCT01538732 Phase 2 alitretinoin
13 Treatmant of Oral Lichen Planus With Lycopene Completed NCT00656214 Phase 2 Lycopene;Placebo
14 Pimecrolimus Cream for Oral Lichen Planus Completed NCT00297037 Phase 2 Pimecrolimus 1% cream
15 Efficacy of Purslane in Treatment of Oral Lichen Planus Completed NCT00746772 Phase 2 Purslane 235mg/day in one dosage;Placebo : one dosage
16 A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planus Completed NCT00525421 Phase 2 Curcuminoids;Placebo
17 The Efficacy of Omega-3 in Treatment of Atrophic/Erosive Lichen Planus Completed NCT02106468 Phase 2 Prednisone tablet 5mg;Omega-3 soft capsules 1000 mg
18 Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus Completed NCT02453503 Phase 2 Licorice;Triamcinolone Acetonide
19 Dexamethasone to Treat Oral Lichen Planus Completed NCT00111072 Phase 2 dexamethasone 0.01% solution
20 Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral Lichen Planus Completed NCT00102557 Phase 2 Hydroxychloroquine
21 Cedar Honey in Oral Lichen Planus Completed NCT01974414 Phase 1, Phase 2 orally administered cedar honey
22 Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planus Completed NCT02744378 Phase 2 Tacrolimus 0.1%;Clobetasol 0.05%
23 Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Other Completed NCT00484250 Phase 2 metronidazole,doxycycline
24 Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases Completed NCT02920658 Phase 2 NAVS Naphthalan;0.05% Betamethasone dipropionate
25 Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus Recruiting NCT03026478 Phase 2 Betamethasone Dipropionate;Clobetasol Propionate
26 Serum Cortisol Levels in Patients With Anxiety and Depression With Symptomatic Oral Lichen Planus Recruiting NCT03011658 Phase 1, Phase 2
27 Dexamethasone Solution for the Treatment of Oral Lichen Planus Not yet recruiting NCT02850601 Phase 2 Dexamethasone
28 Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus Not yet recruiting NCT03293368 Phase 2 Triamcinolone Acetonide
29 A Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Curcuminoids in Oral Lichen Planus Terminated NCT00226174 Phase 2 Curcuminoids
30 Treatment of Oral Erosive Lichen Planus With Pimecrolimus Cream Terminated NCT00321750 Phase 2 1% pimecrolimus cream
31 A Safety and Efficacy Study of Alefacept in the Treatment of Moderate to Severe Erosive Mucosal Lichen Planus Terminated NCT00135733 Phase 2 Amevive (Alefacept);Placebo
32 Use of Etanercept in the Treatment of Moderate to Severe Lichen Planus Terminated NCT00285779 Phase 2 Etanercept;Placebo
33 Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain Terminated NCT01584947 Phase 2 Bupivacaine;Placebo
34 Free Soft Tissue Graft in Treatment of Oral Lichen Planus Unknown status NCT00737854 Phase 1
35 Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus Unknown status NCT01375101 Phase 1 placebo;Quercetin
36 Incidence of Esophageal Lichen Planus in Patients With Known Oral Lichen Planus Unknown status NCT02532166
37 Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen Planus Unknown status NCT02276573
38 Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV Infection Unknown status NCT02261662 Ribavirin;Betamethasone
39 Expression of miRNa-138 and Cyclin D1 in Oral Mucosa of Patients With Oral Lichen Planus Completed NCT02834520
40 Impact of Continuous Defocused CO2 Laser Vaporisation on the Histological Malignant Transformation of Erosive Oral Lichen Planus in Patients Completed NCT02154607
41 Safety and Effectiveness of Efalizumab to Treat Oral Lichen Planus Completed NCT00133107 efalizumab
42 The Use of Probiotics in Patients With Symptomatic Oral Lichen Planus Completed NCT01743690 Nystatin;fluocinolone
43 The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 and IGF2) Completed NCT03257228
44 Molecular Mechanisms of the Development of Precancerous and Cancerous Lesions of the Oral Cavity Completed NCT03026361
45 Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection Efficacy Completed NCT03031899
46 Biomarkers for Oral Cancer Completed NCT00341497
47 Clinical Research Core Dental Screening Protocol Completed NCT00090818
48 Evaluation and Treatment of Oral Soft Tissue Diseases Completed NCT00001601
49 Exploratory Study of Natural Killer Cells in Human Skin Completed NCT00824889
50 Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions Completed NCT02323672

Search NIH Clinical Center for Lichen Planus

Cochrane evidence based reviews: lichen planus

Genetic Tests for Lichen Planus

Anatomical Context for Lichen Planus

MalaCards organs/tissues related to Lichen Planus:

39
Skin, Tongue, T Cells, Thyroid, Testes, Endothelial, Liver

Publications for Lichen Planus

Articles related to Lichen Planus:

(show top 50) (show all 1491)
id Title Authors Year
1
Primary extramedullary plasmacytoma mimicking oral lichen planus. ( 28944756 )
2017
2
Diagnosis, Treatment, and Surgical Repair in a Case of Isolated Conjunctival Lichen Planus Causing Cicatricial Entropion. ( 28538610 )
2017
3
DEFB1 polymorphisms and salivary hBD-1 concentration in Oral Lichen Planus patients and healthy subjects. ( 27770642 )
2017
4
IL-17A polymorphism and elevated IL-17A serum levels are associated with oral lichen planus. ( 28741807 )
2017
5
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma ( 28749626 )
2017
6
Lichen Planus triggered by infliximab biosimilar CT-P13 and recurred during secukinumab treatment. ( 28940185 )
2017
7
Incidence of Oral Lichen Planus in Perimenopausal Women: A Cross-sectional Study in Western Uttar Pradesh Population. ( 28706407 )
2017
8
Immune receptors CD40 and CD86 in oral keratinocytes and implications for oral lichen planus. ( 28904313 )
2017
9
Efficacy of steroidal vs non-steroidal agents in oral lichen planus: a randomised, open-label study. ( 27917729 )
2017
10
Lichen planus pigmentosus in a blaschkoid distribution. ( 28633749 )
2017
11
Squamous Cell Carcinoma Arising from Hypertrophic Lichen Planus. ( 28761854 )
2017
12
Semaphorin4D Drives CD8(+) T-Cell Lesional Trafficking in Oral Lichen Planus via CXCL9/CXCL10 Upregulations in OralA Keratinocytes. ( 28760660 )
2017
13
Hypohidrosis and metal allergy: Trigger factors for unilateral lichen planus. ( 28342246 )
2017
14
Is chronic ulcerative stomatitis a variant of lichen planus, or a distinct disease? ( 28186659 )
2017
15
Association between -1082a88A/G polymorphism in IL-10 and oral lichen planus: A meta-analysis. ( 28094099 )
2017
16
Evidence of genetic factors involved in oral lichen planus pathogenesis. ( 28736881 )
2017
17
The relationship between levels of salivary and serum interleukin-6 and oral lichen planus: A systematic review and meta-analysis. ( 28712412 )
2017
18
TRPA1 may contribute to the exacerbation of oral lichen planus through Koebner phenomenon. ( 28067971 )
2017
19
Clinical and Histopathological Findings of Frontal Fibrosing Alopecia-Associated Lichen Planus Pigmentosus. ( 28560214 )
2017
20
A clitoral verrucous carcinoma in an area of lichen planus has aggressive features. ( 28061900 )
2017
21
Treatment of oral lichen planus using 308-nm excimer laser. ( 28833900 )
2017
22
Bullous lichen planus - a review. ( 28539981 )
2017
23
Triggers of oral lichen planus flares and the potential role of trigger avoidance in disease management. ( 28732699 )
2017
24
Concepts and controversies in the treatment of cutaneous lichen planus: a review. ( 28895668 )
2017
25
Scoring systems for Oral Lichen Planus used by differently experienced raters. ( 28809373 )
2017
26
Salivary and serum levels of tumor necrosis factor-alpha in oral lichen planus: a systematic review and meta-analysis study. ( 28823317 )
2017
27
Integrative analysis of mRNA and miRNA expression profiles in oral lichen planus: preliminary results. ( 28743667 )
2017
28
Mucin 5B in saliva and serum of patients with oral lichen planus. ( 28935947 )
2017
29
Coexistence of lichen planus follicularis tumidus and Hashimoto's thyroiditis. ( 28954124 )
2017
30
A case of chilblain lupus erythematosus with lupus erythematosus/lichen planus overlap syndrome. ( 28322475 )
2017
31
Fractional carbon dioxide laser in combination with topical corticosteroid: An innovative treatment for hypertrophic lichen planus. ( 28807121 )
2017
32
Bullous lichen planus accompanied by elevation of serum anti-BP180 autoantibody: A possible transitional mechanism to lichen planus pemphigoides. ( 28105695 )
2017
33
Using the BITOLA system to identify candidate molecules in the interaction between oral lichen planus and depression. ( 27913255 )
2017
34
Identification of AgNORs and cytopathological changes in oral lichen planus lesions. ( 27916273 )
2017
35
Salivary levels of interleukin-8 in oral lichen planus and diabetic patients: A biochemical study. ( 28702063 )
2017
36
Isolated Actinic Lichen Planus of the Lower Lip. ( 28559811 )
2017
37
Expression of small leucine-rich extracellular matrix proteoglycans biglycan and lumican reveals oral lichen planus malignant potential. ( 28779221 )
2017
38
Diagnostic value of immunohistochemistry staining of Bcl-2, CD34, CD20 and CD3 for distinction between discoid lupus erythematosus and lichen planus in the skin. ( 28631630 )
2017
39
Erosive Lichen Planus. ( 28778640 )
2017
40
Pembrolizumab-induced lichen planus pemphigoides in a patient with metastatic melanoma. ( 28622432 )
2017
41
Efficacy of low-level laser therapy compared to steroid therapy in the treatment of oral lichen planus: A systematic review. ( 28766756 )
2017
42
MicroRNAs in cutaneous lichen planus. ( 28940245 )
2017
43
Does the corticotropin-releasing hormone system play a role in the pathogenesis of lichen planus? ( 28951706 )
2017
44
Pembrolizumab-induzierter Lichen planus pemphigoides bei einem Patienten mit metastasiertem Melanom. ( 28677196 )
2017
45
Treatment of oral lichen planus. Systematic review and therapeutic guide. ( 28756997 )
2017
46
Generalized lichen planus developing at the healed sites of erythema multiforme in a human immunodeficiency virus-seropositive patient. ( 28540867 )
2017
47
Lichen Planus Pigmentosus Inversus Caused by Occupational Systemic Sensitization to Metals in a Semiconductor Factory Worker. ( 28614105 )
2017
48
Genome-wide Association Study Identifies Risk Variants for Lichen Planus in Patients With Hepatitis C Virus Infection. ( 28065765 )
2017
49
Interventions for the management of Oral lichen planus: A review of the conventional and novel therapies. ( 28055124 )
2017
50
Linear Lichen Planus: Continuum From Skin to Mucosa. ( 28922940 )
2017

Variations for Lichen Planus

Expression for Lichen Planus

Search GEO for disease gene expression data for Lichen Planus.

Pathways for Lichen Planus

Pathways related to Lichen Planus according to GeneCards Suite gene sharing:

(show all 35)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.72 CXCL9 GZMB ICAM1 IFNG IL4 ITGAL
2
Show member pathways
12.64 ICAM1 IFNG IL4 MX1 TLR9 TNF
3 12.5 GZMB IFNG IL4 TLR9 TNF
4
Show member pathways
12.41 GZMB ICAM1 IFNG IL4 ITGAL TNF
5 12.38 ICAM1 ITGAL TNF TP53
6
Show member pathways
12.3 DSG3 FLG IVL KRT10 KRT13 KRT16
7
Show member pathways
12.29 DEFB4A IFNG IL4 TNF
8 12.26 ICAM1 IFNG ITGAL TP53
9 12.15 IFNG TLR9 TNF TP53
10
Show member pathways
12.1 IFNG IL4 MX1 TNF
11
Show member pathways
12.09 DEFB4A IFNG IL4 TLR9 TNF
12 12.05 ICAM1 IFNG TNF TP53
13 11.93 IFNG IL4 ITGAL TNF
14 11.91 ICAM1 IL4 TNF TP53
15
Show member pathways
11.83 GZMB IFNG IL4 TLR9
16 11.8 ICAM1 IFNG IL4 TNF TP53
17 11.77 ICAM1 IFNG ITGAL TNF
18
Show member pathways
11.72 IFNG IL4 TNF
19 11.72 IFNG TLR9 TNF
20 11.71 ICAM1 IFNG IL4 TP53
21
Show member pathways
11.62 ICAM1 IFNG TNF
22
Show member pathways
11.6 GZMB IFNG TNF
23 11.56 ICAM1 ITGAL KRT10
24 11.52 IFNG TNF TP53
25 11.49 ICAM1 IL4 TNF
26 11.46 CXCR3 GZMB IFNG IL4 TNF
27 11.44 ICAM1 IFNG ITGAL
28
Show member pathways
11.36 GZMB IFNG TNF
29 11.34 CXCL9 ICAM1 IFNG
30 11.28 CXCL9 CXCR3 ITGAL
31 11.25 IFNG IL4 TNF
32 11.2 ICAM1 IL4 ITGAL TLR9 TNF
33 11.19 IFNG IL4 TNF
34 11.1 ICAM1 IFNG TLR9 TNF
35 10.71 ICAM1 IFNG ITGAL TLR9 TNF

GO Terms for Lichen Planus

Cellular components related to Lichen Planus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.92 CXCL9 DEFB4A ICAM1 IFNG IL4 KRT10
2 intermediate filament GO:0005882 9.55 DST FLG KRT10 KRT13 KRT16
3 hemidesmosome GO:0030056 9.26 COL17A1 DST
4 cornified envelope GO:0001533 9.26 DSG3 FLG IVL KRT10
5 external side of plasma membrane GO:0009897 9.1 CXCL9 CXCR3 ICAM1 IFNG IL4 TNF

Biological processes related to Lichen Planus according to GeneCards Suite gene sharing:

(show all 24)
id Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.88 DEFB4A IFNG TLR9 TNF
2 inflammatory response GO:0006954 9.85 CXCL9 CXCR3 ITGAL KRT16 TLR9 TNF
3 chemotaxis GO:0006935 9.83 CXCL9 CXCR3 DEFB4A IL4
4 defense response GO:0006952 9.8 CXCL9 DEFB4A MX1 TNF
5 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.79 ICAM1 IL4 TP53
6 movement of cell or subcellular component GO:0006928 9.77 CXCR3 IFNG ITGAL
7 peptide cross-linking GO:0018149 9.72 FLG IVL KRT10
8 keratinization GO:0031424 9.72 DSG3 IVL KRT10 KRT13 KRT16
9 positive regulation of nitric oxide biosynthetic process GO:0045429 9.69 ICAM1 IFNG TNF
10 regulation of immune response GO:0050776 9.65 COL17A1 ICAM1 IFNG IL4 ITGAL
11 T cell chemotaxis GO:0010818 9.61 CXCL9 CXCR3
12 positive regulation of isotype switching to IgG isotypes GO:0048304 9.59 IFNG IL4
13 skin epidermis development GO:0098773 9.58 FLG KRT10
14 positive regulation of MHC class II biosynthetic process GO:0045348 9.56 IFNG IL4
15 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.54 ICAM1 TNF
16 positive regulation of mononuclear cell migration GO:0071677 9.48 IL4 TNF
17 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:0002291 9.46 ICAM1 ITGAL
18 keratinocyte differentiation GO:0030216 9.46 FLG IVL KRT10 KRT16
19 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.43 IFNG TNF
20 positive regulation of vitamin D biosynthetic process GO:0060557 9.4 IFNG TNF
21 positive regulation of immunoglobulin production GO:0002639 9.27 IL4
22 positive regulation of chemokine biosynthetic process GO:0045080 9.13 IFNG IL4 TNF
23 cornification GO:0070268 9.1 DSG3 FLG IVL KRT10 KRT13 KRT16
24 immune response GO:0006955 10 CXCL9 DEFB4A IFNG IL4 TNF

Molecular functions related to Lichen Planus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 CXCL9 IFNG IL4 TNF
2 structural constituent of epidermis GO:0030280 9.16 FLG KRT10
3 structural molecule activity GO:0005198 8.92 FLG IVL KRT13 KRT16

Sources for Lichen Planus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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