MCID: LCH008
MIFTS: 17

Lichen Planus Pigmentosus malady

Skin category

Summaries for Lichen Planus Pigmentosus

Sources:
43NIH Rare Diseases, 33MalaCards
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NIH Rare Diseases:43 Lichen planus (lp) pigmentosus is a rare variant of lichen planus and is characterized by the presence of hyperpigmented, dark-brown macules in sun-exposed or skin-fold areas of the body. lp pigmentosus is a rare disease in europe but it is common in indian populations and in the middle east. the disease usually appears in the third and fourth decade of life. the lesions usually do not cause symptoms. the exact cause of lp pigmentosus is unknown but various factors (e.g. viral infections and certain topical agents including mustard oil, amla oil and henna hair dyes) can trigger the disease. lichen planus pigmentosus seems to follow a chronic and progressive course. last updated: 2/29/2012

MalaCards: Lichen Planus Pigmentosus, also known as lichen planus pigmentosus inversus, is related to lichen planus and linear lichen planus. An important gene associated with Lichen Planus Pigmentosus is SLC17A5 (solute carrier family 17 (acidic sugar transporter), member 5). Affiliated tissues include skin.

Aliases & Classifications for Lichen Planus Pigmentosus

Sources:
43NIH Rare Diseases, 49Orphanet, 61UMLS, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin


Characteristics (Orphanet epidemiological data):

49
lichen planus pigmentosus inversus:
Age of onset: Adulthood


Aliases & Descriptions:

lichen planus pigmentosus 43 49
lichen planus pigmentosus inversus 43 49
lichen planus pigmentosa 43 49
lp pigmentosus 43 49
lp pigmentosa 43 49
post-inflammatory hyperpigmentation in lichen planus 61


External Ids:

ICD10 via Orphanet26 L43.8

Related Diseases for Lichen Planus Pigmentosus

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Lichen Planus Pigmentosus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1lichen planus11.1
2linear lichen planus10.7
3frontal fibrosing alopecia10.5
4oral lichen planus10.5
5hepatitis b10.3
6acral lentiginous melanoma10.3
7hepatitis b virus infection10.3

Graphical network of diseases related to Lichen Planus Pigmentosus:



Diseases related to lichen planus pigmentosus

Clinical Features for Lichen Planus Pigmentosus

Drugs & Therapeutics for Lichen Planus Pigmentosus

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Lichen Planus Pigmentosus

Drug clinical trials:

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Search NIH Clinical Center for Lichen Planus Pigmentosus

Search CenterWatch for Lichen Planus Pigmentosus

Genetic Tests for Lichen Planus Pigmentosus

Anatomical Context for Lichen Planus Pigmentosus

Sources:
33MalaCards
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MalaCards organs/tissues related to Lichen Planus Pigmentosus:

33
Skin

Animal Models for Lichen Planus Pigmentosus or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Lichen Planus Pigmentosus

Sources:
51PubMed
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Articles related to Lichen Planus Pigmentosus:

(show all 40)
idTitleAuthorsYear
1
Coexistence of frontal fibrosing alopecia with lichen planus pigmentosus. (23557015)
2013
2
Lichen planus pigmentosus. (24147180)
2013
3
Lichen planus pigmentosus. (24147181)
2013
4
Lichen planus pigmentosus. (24365004)
2013
5
Lichen planus pigmentosus. (23745228)
2013
6
Lichen planus pigmentosus inversus. (24346904)
2013
7
Lichen planus pigmentosus distributed along the lines of Blaschko. (21349081)
2013
8
Two cases of lichen planus pigmentosus inversus: possible causative role of tightly fitting underclothes. (24185938)
2013
9
Lichen planus pigmentosus-inversus involving the post-auricular sulci. (24011320)
2013
10
Frontal fibrosing alopecia and lichen planus pigmentosus: is there a link? (22803712)
2013
11
Linear lichen planus pigmentosus of the forehead treated by neodymium:yttrium-aluminum-garnet laser and topical tacrolimus. (21951348)
2012
12
Lichen planus pigmentosus-inversus: case report and review of an unusual entity. (22398232)
2012
13
Lichen planus pigmentosus-inversus occurring extensively in multiple intertriginous areas. (22035127)
2012
14
A Case of Lichen Planus Pigmentosus-inversus in a Korean Patient. (21738364)
2011
15
Lichen planus pigmentosus over superficial leg veins. (21251228)
2011
16
Clinicopathological characteristics of lichen planus pigmentosus and its response to tacrolimus ointment: an open label, non-randomized, prospective study. (19840200)
2010
17
A case of linear lichen planus pigmentosus. (20711271)
2010
18
Bilateral Linear Lichen Planus Pigmentosus Associated with Hepatitis C Virus Infection. (21060775)
2010
19
Unilateral lichen planus pigmentosus mimicking acral lentiginous melanoma. (20677541)
2010
20
Lichen planus pigmentosus presenting as generalized reticulate pigmentation with scalp involvement. (19236412)
2009
21
Apoptosis and proliferation in oral lichen planus pigmentosus. (19207644)
2009
22
Coexistence of lichen planus pigmentosus and minimal change nephrotic syndrome. (19451054)
2009
23
Coexistence of classic lichen planus and lichen planus pigmentosus-inversus: resistant to both tacrolimus and clobetasol propionate ointments. (18181983)
2008
24
Two Japanese cases of lichen planus pigmentosus-inversus. (17614807)
2007
25
Two cases of lichen planus pigmentosus presenting with a linear pattern. (14966361)
2004
26
Linear hyperpigmentation with extensive epidermal apoptosis: a variant of linear lichen planus pigmentosus? (15097934)
2004
27
Lichen planus pigmentosus presenting as diffuse facial melanosis. (15303789)
2004
28
A study of 124 Indian patients with lichen planus pigmentosus. (12950331)
2003
29
Pigmented and reticulated plaques of folds. A case of lichen planus pigmentosus-inversus? (11989481)
2002
30
Lichen planus pigmentosus-inversus. (11763389)
2001
31
Lichen planus pigmentosus associated with acrokeratosis of Bazex. (8313644)
1994
32
Ashy dermatosis and lichen planus pigmentosus: a clinicopathologic study of 31 cases. (1559749)
1992
33
Ashy dermatosis versus lichen planus pigmentosus: a controversial matter. (1559747)
1992
34
Lichen planus pigmentosus. (2254494)
1990
35
Lichen planus pigmentosus. (2624641)
1989
36
Ashy dermatosis or lichen planus pigmentosus: what is in a name? (3947116)
1986
37
Lichen planus pigmentosus of the oral mucosa: a rare clinical variety. (7227608)
1981
38
Vitamin A in the treatment of lichen planus pigmentosus. (454573)
1979
39
Pigmented contact dermatitis vs lichen planus pigmentosus. (598959)
1977
40
Lichen planus pigmentosus. (4154221)
1974

Genetic Variations for Lichen Planus Pigmentosus

Expression for genes affiliated with Lichen Planus Pigmentosus

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lichen Planus Pigmentosus

Search GEO for disease gene expression data for Lichen Planus Pigmentosus.

Pathways for genes affiliated with Lichen Planus Pigmentosus

Compounds for genes affiliated with Lichen Planus Pigmentosus

GO Terms for genes affiliated with Lichen Planus Pigmentosus

Products for genes affiliated with Lichen Planus Pigmentosus

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Lichen Planus Pigmentosus

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet