MCID: LCH009
MIFTS: 47

Lichen Sclerosus malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Lichen Sclerosus

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Aliases & Descriptions for Lichen Sclerosus:

Name: Lichen Sclerosus 45 47
Lichen Sclerosus Et Atrophicus 45 65
 
Lichen Sclerosis Et Atrophicus 45
Lichen Sclerosis 45

Characteristics:



Classifications:



External Ids:

ICD1027 L90.0
UMLS65 C0023652

Summaries for Lichen Sclerosus

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NIH Rare Diseases:45 Lichen sclerosus is a chronic skin disorder that is more common in women, most often affecting the external part of the vagina (vulva) or the area around the anus. in men, it typically affects the tip of the penis. it can occur at any age but is usually seen in women over age 50. some people have no symptoms, while others may experience itchiness (sometimes severe), discomfort, or blistering. it often lasts for years and can cause permanent scarring. the underlying cause of lichen sclerosus is not fully understood but it is thought to relate to an autoimmune process. treatment may include topical steroids or other types of topical creams and/or surgery. last updated: 5/26/2015

MalaCards based summary: Lichen Sclerosus, also known as lichen sclerosus et atrophicus, is related to psoriasis and vasculitis, and has symptoms including abnormality of reproductive system physiology, hyperkeratosis and pruritus. An important gene associated with Lichen Sclerosus is ECM1 (Extracellular Matrix Protein 1), and among its related pathways are Cell adhesion_Cell-matrix glycoconjugates and Hematopoietic cell lineage. Affiliated tissues include skin, liver and breast.

Wikipedia:68 Lichen sclerosus (LS), and also known as lichen sclerosus et atrophicus (LSetA) [also termed,... more...

Related Diseases for Lichen Sclerosus

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Diseases related to Lichen Sclerosus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 140)
idRelated DiseaseScoreTop Affiliating Genes
1psoriasis30.4HLA-DQB1, HLA-DRB1
2vasculitis30.0CD44, TP53
3artery disease29.8HLA-DQB1, HLA-DRB1
4balanitis xerotica obliterans11.8
5lichen planus10.5
6urethritis10.4
7phimosis10.4
8balanitis10.3
9urethral stricture10.3
10renal artery obstruction10.3CD44, TP53
11colonic l-cell glucagon-like peptide producing tumor10.3CD44, TP53
12salivary gland adenoid cystic carcinoma10.3CD44, TP53
13vulvar benign neoplasm10.3HLA-DRB1, TP53
14childhood pilocytic astrocytoma10.3CD44, TP53
15vulvar intraepithelial neoplasia10.2
16lichen planus pemphigoides10.2HLA-DQB1, HLA-DRB1
17tucker syndrome10.2HLA-DQB1, HLA-DRB1
18heavy chain deposition disease10.2HLA-DQB1, HLA-DRB1
19pulmonary coin lesion10.2HLA-DQB1, HLA-DRB1
20autoimmune polyglandular syndrome type 210.2HLA-DQB1, HLA-DRB1
21best1 retinopathy10.2HLA-DQB1, HLA-DRB1
22idiopathic juxtafoveal retinal telangiectasia10.2HLA-DQB1, HLA-DRB1
23non-distal monosomy 10q10.2HLA-DQB1, HLA-DRB1
24granuloma annulare10.2
25hepatitis10.2
26melanoma10.2
27thyroiditis10.2
28red cell phospholipid defect with hemolysis10.2HLA-DQB1, HLA-DRB1
29actinomycosis10.1HLA-DQB1, HLA-DRB1
30finnish upper limb-onset distal myopathy10.1HLA-DQB1, HLA-DRB1
31metanephric adenoma10.1HLA-DQB1, HLA-DRB1
32nut allergy10.1HLA-DQB1, HLA-DRB1
33lymphocytic choriomeningitis10.1HLA-DQB1, HLA-DRB1
34moderately severe hemophilia a10.1HLA-DQB1, HLA-DRB1
35angioid streaks10.1HLA-DQB1, HLA-DRB1
36pulmonary nodular lymphoid hyperplasia10.1HLA-DQB1, HLA-DRB1
37cytoplasmic body myopathy10.1HLA-DQB1, HLA-DRB1
38atopy10.1
39breast cancer10.1
40vaginitis10.1
41localized scleroderma10.1
42chronic graft versus host disease10.1
43hypertonia10.1HLA-DQB1, HLA-DRB1
44hypothalamic disease10.1CD44, TP53
45bipolar ll disorder10.1HLA-DQB1, HLA-DRB1
46hepatoid adenocarcinoma10.1HLA-DQB1, HLA-DRB1
47bubonic plague10.1HLA-DQB1, HLA-DRB1
48kernicterus due to isoimmunization10.1HLA-DQB1, HLA-DRB1
49tenosynovitis of foot and ankle10.1CD44, TP53
50ichthyosis-hypotrichosis-sclerosing cholangitis syndrome10.0HLA-DQB1, HLA-DRB1

Graphical network of the top 20 diseases related to Lichen Sclerosus:



Diseases related to lichen sclerosus

Symptoms for Lichen Sclerosus

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HPO human phenotypes related to Lichen Sclerosus:

(show all 13)
id Description Frequency HPO Source Accession
1 abnormality of reproductive system physiology hallmark (90%) HP:0000080
2 hyperkeratosis hallmark (90%) HP:0000962
3 pruritus hallmark (90%) HP:0000989
4 constipation hallmark (90%) HP:0002019
5 aplasia/hypoplasia of the skin hallmark (90%) HP:0008065
6 abnormality of the gastrointestinal tract hallmark (90%) HP:0011024
7 abnormal renal physiology hallmark (90%) HP:0012211
8 lichenification hallmark (90%) HP:0100725
9 autoimmunity occasional (7.5%) HP:0002960
10 psoriasis occasional (7.5%) HP:0003765
11 vaginal neoplasm occasional (7.5%) HP:0100650
12 verrucae occasional (7.5%) HP:0200043
13 squamous cell carcinoma HP:0002860

Drugs & Therapeutics for Lichen Sclerosus

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Drugs for Lichen Sclerosus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1HormonesPhase 3, Phase 211748
2Anti-Inflammatory AgentsPhase 3, Phase 28478
3Hormone AntagonistsPhase 3, Phase 210002
4Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 3, Phase 29988
5glucocorticoidsPhase 3, Phase 23896
6
ClobetasolPhase 3, Phase 27025122-46-732798, 5311051
Synonyms:
(11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
(9R,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
25122-41-2
AC-1775
AC1L1OG6
AC1NDRJ9
AC1NSJWK
BB_NC-1906
C22H28ClFO4
CHEBI:205919
CHEMBL1201362
CID10341542
CID32797
 
CID4630419
CID5311051
CID9844480
Clobecort Amex
Clobecort Amex (TN)
Clobetasol (INN)
Clobetasol [INN:BAN]
Clobetasolum
Clobetasolum [INN-Latin]
Clofenazon
D07715
EINECS 246-633-8
LS-174086
MolPort-005-909-335
NCGC00164580-01
STK801976
UNII-ADN79D536H
ZINC26892643
clobetasol
7
HydrocortisoneapprovedPhase 258350-23-75754, 657311
Synonyms:
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
1 Hydrocortisone maximum strength
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
999 Itch Relieving
A-hydrocort
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Advanced Hydrocortisone
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti Itch
Anti Itch maximum strength
Anti Itch maximum strength plus
Anti-inflammatory hormone
Anti-itch
Anti-itch Scalp Relief Maximum Strength
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Apres Peel Soothing Balm
Aquacort
Aquanil HC
Atopalm Maximum Strength Anti-itch
Atopalm Moisturizing Hydrocortisone
Aveeno Hydrocortisone Anti Itch
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
Bioelements Immediate Comfort Hydrocortisone
Budpak Anti-itch
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Caldecort
Care One Hydrocortisone maximum strength
Cetacort
Chronocort
Cicatricure Ultra Moisturizing
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortaid 12-hour Advanced Anti-Itch
Cortaid Intensive Therapy Cooling
Cortaid Maximum Strength
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisone
Cortisone Cream Intensive Healing
Cortisone Maximum Strength
Cortisone maximum strength
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortizone 10
Cortizone 10 Cooling Cream Anti-itch
Cortizone 10 Cooling Relief
Cortizone 10 Easy Relief
Cortizone 10 Hydratensive Healing Anti Itch
Cortizone 10 Hydratensive Soothing Anti Itch
Cortizone 10 Intensive Healing
Cortizone 10 Intensive Healing Feminine Itch Relief
Cortizone 10 Intensive Healing For Eczema
Cortizone 10 Plus
Cortizone 10 Poison Ivy Relief Pads
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cvs Anti-itch Hydrocortisone
Cvs Cools Itch Fast
Cvs Cortisone
Cvs Pharmacy Anti-itch
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermacort Anti-Itch
Dermaquest Skin Therapy Post-skin Resurfacing Balm
Dermarest Eczema Medicated
Dermaspray
Dermil
Dermocortal
Dermolate
Dg Health Hydrocortisone
Dg Health Hydrocortisone Cream Maximum Strength
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Dr. Sheffield Hydrocortisone Anti Itch
Drotic
Duane Reade
Duane Reade hydrocortisone
Duane Reade hydrocortisone plus 12 moisturizers
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Equaline Anti Itch
Equaline Anti Itch maximum strength
Equate Hydrocortisone
Esiderm H
Evacort
Family Care Hydrocortisone
Family Wellness
Family Wellness Hydrocortisone
Family Wellness Maximum Strength Hydrocortisone
Ficortril
Fiocortril
Fixmyskin Healing Balm Fragrance-free
Fixmyskin Healing Balm Unflavored
Fixmyskin Healing Balm Vanilla Flavor
Fixmyskin Healing Balm Vanilla Fragrance
Flexicort
Foille Insetti
Formu Care Anti Itch maximum strength
Fulton Street Market Anti Itch
Genacort
Genacort (lotion)
Genuine Hydrocortisone
Glycort
Good Neighbor Pharmacy Anti Itch
Good Neighbor Pharmacy Hydrocortisone
Good Neighbor Pharmacy Hydrocortisone Plus 12 Moisturizers
Good Sense Anti Itch
Gyno-Cortisone
H 4001
H-Cort
H-releve Anti-itch
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Healerz For Itches
Health Mart Pharmacy Hydrocortisone Maximum Strength Plus 12 Moisturizers
Healthy Accents Cortisone maximum strength
Heb Cort
Heb-Cort
 
Hem-easy Relief Herbal Anti-itch Maximum Itch Relief
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro Skin
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone 1 plus 10
Hydrocortisone Acetate
Hydrocortisone Anti-itch Plus
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone D
Hydrocortisone HC
Hydrocortisone Intensive Healing Formula
Hydrocortisone Maximum Strength
Hydrocortisone Maximum Strength Plus 12 Moisturizers
Hydrocortisone Plus
Hydrocortisone Plus 12 Moisturizers
Hydrocortisone Probutate
Hydrocortisone Regular Strength
Hydrocortisone Sodium Phosphate
Hydrocortisone Ultra Strength
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone anti itch
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone maximum strength
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Intensive Healing Anti Itch
Kaiser Permanente Hydrocortisone
Kendall'S compound F
Kendall's compound F
Kera Hc Hydrocortisone
Kirkland Signature Hydrocortisone Plus maximum strength
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Leader Hydrocortisone
Locoid
Loesch Anti-Itch Therapy
Lopac0_000594
Lubricort
Lucky Supersoft MAXIMUM STRENGTH
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Makesense MAXIMUM STRENGTH
Maximum Strength Cortizone 10 Quick Shot 360 Continuous
Maximum Strength Hydrocortisone
Maximum-h
Medicort
Medpride
Meijer Anti Itch
Meijer Anti Itch Cream Plus
Meijer Hydrocortisone
Meijer Hydrocortisone Plus 12 Moisturizers
Members Mark Hydrocortisone
Meusicort
Mildison
Milliderm
MolPort-001-794-637
Monistat Complete Care Instant Itch Relief
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Natureplex Hydrocortisone Hydro
Neo-Cort-Dome
Neo-Cortef
Neosporin Eczema Essentials Anti Itch
Neosporin-H Ear
Nogenic HC
Nu-derm Tolereen Anti-pruritic
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pandel
Pediaderm Hc
Pediotic Suspension
Penecort
Permicort
Piyanping Antiitch
Polcort H
Premier Value Hydrocortisone
Premier Value Hydrocortisone Plus 12 Moisturizers
Preparation H Hydrocortisone
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proactiv Solution Anti-itch Scalp
Procto-pak
Proctocort
Proctocream HC
Proctofoam
Proctosol-hc
Proctozone HC
Procure
Protocort
Publix Hydro
Publix hydro plus
Quadrydern
Quality Choice Hydrocortisone
Quality Choice Hydrocortisone Maximum Strength
Quality Choice Maximum Strength Anti Itch
Racet
Rectasol-HC
Rectoid
Refuge Hc
Reichstein'S substance M
Reichstein's substance M
Remederm HC
Rexall Anti Itch maximum strength relief
Rexall Hydrocortisone 1
Rexall Hydrocortisone plus moisturizers
Rite Aid anti-itch
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Safeway Hydrocortisone Plus 12 Moisturizers
Sanatison
Scalp-Cort
Scalpicin Anti-Itch Maximum Strength
Scalpicin Capilar
Scalpicin Maximum Strength
Scalpicin Scalp Itch Medication Maximum Strength
Schericur
Scheroson F
Shopko Hydrocortisone
Shopko Hydrocortisone Intensive Healing Formula
Shopko Hydrocortisone Maximum Strength
Shopko Hydrocortisone Plus 12 Moisturizers Maximum Strength
Shopko Maximum Strength
Shoprite Hydrocortisone
Sigmacort
Signef
Smart Sense Anti Itch
Smart Sense Anti Itch maximum strength
Smart Sense Hydrocortisone
Solu-cortef
Soothe Rodan Fields
Stie-cort
Stiefcorcil
Sunmark Hydrocortisone
Sunmark Hydrocortisone Plus 12 Moisturizers
Synacort
Systral Hydrocort
Tarcortin
Tecnu Corticool
Texacort
Texacort lotion 25
Thera Plus
Timocort
Topcare Hydrocortisone
Topcare Hydrocortisone Intensive Healing Formula
Topcare Hydrocortisone Plus 12 Moisturizers
Topicort
Transderma H
Traumaide
Truelipids Anti-itch Barrier
U-cort
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Walgreens Hydrocortisone Plus 12 Moisturizers
Westcort
Western Family HydroCortisone
Western Family HydroCortisone Plus 12 Moisturizers
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
8
Tacrolimusapproved, investigationalPhase 21023104987-11-3445643, 439492, 445647
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
8-DEETHYL-8-[but-3-enyl]-ascomycin
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
FR900506
 
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
Hecoria
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus Hydrate
Tacrolimus anhydrous
Tacrolimus hydrate
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
9
Pimecrolimusapproved, investigationalPhase 260137071-32-06447131, 17753757
Synonyms:
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-((E)-2-((1R,3R,4S)-4-chloro-3-methoxycyclohexyl)-1-methylvinyl)-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,26,26a-hexadecahydro-5,19-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,17,20,21(4H,23H)-tetrone
137071-32-0
33-Epi-chloro-33-desoxyascomycin
33-epi-Chloro-33-desoxyascomycin
ASM 981
ASM-981
ASM-998
CHEMBL1200686
CID6447131
CID6509979
CID6916008
D05480
DB00337
 
Elidel
Elidel (TN)
I06-1252
LS-181798
MolPort-003-666-749
NCGC00167506-01
Pimecrolimus
Pimecrolimus (JAN/USAN/INN)
Pimecrolimus [USAN:INN:BAN]
Pimecrolimusum
S5004_Selleck
SDZ ASM 981
SDZ-ASM 981
SDZ-ASM-981
UNII-7KYV510875
10
ProgesteroneapprovedPhase 250057-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14
11
butyric acidexperimentalPhase 2292107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
12AntipruriticsPhase 2619
13Hydrocortisone-17-butyratePhase 2583
14Hydrocortisone acetatePhase 2583
15Hydrocortisone 17-butyrate 21-propionatePhase 2583
16Cortisol succinatePhase 2583
17Dermatologic AgentsPhase 24555
18Immunosuppressive AgentsPhase 210422
19Peripheral Nervous System AgentsPhase 218510
20Calcineurin InhibitorsPhase 21223
21AnalgesicsPhase 29358
22Immunologic FactorsPhase 218483
23Antirheumatic AgentsPhase 28496
24Anti-Inflammatory Agents, Non-SteroidalPhase 23549
25Analgesics, Non-NarcoticPhase 25184
26ProgestinsPhase 2433
27
Cortisone acetateapproved531950-04-4, 50-04-45745
Synonyms:
Cortisone Acetate
 
Cortisyl
Cortone acetate
28
Cortisone5353-06-5222786
Synonyms:
Andreson
Anusol HC
Balneol-Hc
Colocort
Compound E
Corlin
Cortadren
Cortandren
Cortef
Cortef Acetate
Cortisal
Cortisate
Cortison
Cortisone Acetate
Cortistal
Cortivite
Cortogen
Cortone
Cortril
Dermacort
Dricort
Flexicort
 
Florinef
Fludrocortisone Acetate
Glycort
Hemsol-Hc
Hi-Cor
Incortin
Kendall'S Compound E
Kendall'S compound
Locoid
Locoid Lipocream
Micort-Hc
Nogenic HC
Orabase HCA
Pandel
Prestwick_132
Reichstein Fa
Reichstein'S Substance FA
Scheroson
Solu-Cortef
Stie-Cort
Texacort
Westcort
beta-Hc
29Petrolatum84
30
methylene blue71
Synonyms:
Urolene Blue
aniline violet
 
methylthionine chloride
methylthioninium chloride
methylthioninium chloride Proveblue
tetrametylthionine chloride

Interventional clinical trials:

idNameStatusNCT IDPhase
1Clobetasol Proprionate Versus Radiofrequency CO2 Laser for the Treatment of LichenRecruitingNCT02573883Phase 3
2Tacrolimus Versus Clobetasol Propionate in the Treatment of Vulvar Lichen SclerosusCompletedNCT00757874Phase 2
3Clobetasol Versus Pimecrolimus for Vulvar Lichen SclerosusCompletedNCT00393263Phase 2
4Evaluation of the Antipruritic Effect of Elidel (Pimecrolimus) in Non-atopic Pruritic DiseaseCompletedNCT00507832Phase 2
5Progesterone vs Clobetasol Propionate in Vulvar Lichen SclerosusTerminatedNCT01126255Phase 2
6Topical 0.05% Clobetasol Propionate in Vaseline Versus UVA-1 Phototherapy in Vulvar Lichen SclerosusCompletedNCT01400022
7The Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar DermatosisRecruitingNCT02732145
8Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval DiseaseRecruitingNCT02223975
9Implication of Human Papillomavirus (HPV) in Lichen Physiopathology in Human (HPVLichen)RecruitingNCT02761122
10Vulvar Lichen Sclerosus: Comparison Between Clobetasol Propionate, Photodynamic Therapy and Low-Intensity LaserActive, not recruitingNCT02416531

Search NIH Clinical Center for Lichen Sclerosus

Genetic Tests for Lichen Sclerosus

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Anatomical Context for Lichen Sclerosus

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MalaCards organs/tissues related to Lichen Sclerosus:

33
Skin, Liver, Breast, Prostate, Lung, Thyroid, T cells

Animal Models for Lichen Sclerosus or affiliated genes

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Publications for Lichen Sclerosus

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Articles related to Lichen Sclerosus:

(show top 50)    (show all 587)
idTitleAuthorsYear
1
Lichen sclerosus of soft palate: A rare case report. (27166046)
2016
2
Lichen Sclerosus of Face: A Case Report and Review of Literature. (26955133)
2016
3
Conscious sedation with inhaled 50% nitrous oxide/oxygen premix in photodynamic therapy sessions for vulvar lichen sclerosus treatment. (25672311)
2015
4
Colocalization of nonsegmental vitiligo and extragenital lichen sclerosus in a 45-year-old female patient with Hashimoto's thyroiditis. (25615429)
2015
5
Oral lichen sclerosus expressing extracellular matrix proteins and IgG4-positive plasma cells. (25244166)
2014
6
Responses to the McGill Pain Questionnaire Predict Neuropathic Pain Medication Use in Women in With Vulvar Lichen Sclerosus. (25036743)
2014
7
The impact of vulvar lichen sclerosus on sexual dysfunction. (25162790)
2014
8
Reconstructive surgery of the sulcus of glans penis for balanopreputial adhesion due to lichen sclerosus. Our experience and medicolegal implications. (24901311)
2014
9
Lichen sclerosus in a breast cancer survivor. (23288380)
2013
10
Differential gene hypermethylation in genital lichen sclerosus and cancer: a comparative study. (23998425)
2013
11
What is lichen sclerosus? (24701651)
2013
12
Long-term follow-up of women with genital lichen sclerosus. (23417579)
2013
13
Peristomal lichen sclerosus: the role of occlusion and urine exposure? (22913573)
2013
14
High frequency of genital lichen sclerosus in a prospective series of 76 patients with morphea: toward a better understanding of the spectrum of morphea. (22004877)
2012
15
Clinical scoring system for vulvar lichen sclerosus. (22759453)
2012
16
Coexistence of lichen sclerosus and morphea: a retrospective analysis of 472 patients with localized scleroderma from a German tertiary referral center. (22533994)
2012
17
Rates of self-reported urinary, gastrointestinal, and pain comorbidities in women with vulvar lichen sclerosus. (22622339)
2012
18
Topical interventions for genital lichen sclerosus. (22161424)
2011
19
A double-blind, randomized controlled trial of clobetasol versus pimecrolimus in patients with vulvar lichen sclerosus. (21353334)
2011
20
Risk factors for genital lichen sclerosus in men. (20973765)
2011
21
Acral lichen sclerosus et atrophicus--case report. (22068779)
2011
22
Coexistence of generalized morphea and lichen sclerosus et atrophicus mimicking systemic disease. (21548525)
2011
23
Imiquimod use in the genital area and development of lichen sclerosus and lichen planus. (20215634)
2010
24
Lichen sclerosus et atrophicus-like skin lesions in a patient carrying a novel hydroxymethylbilane synthase mutation. (20580577)
2010
25
Treatment of oral lichen sclerosus with 1% pimecrolimus cream. (20711272)
2010
26
Dermoscopy of extragenital lichen sclerosus. (20026867)
2009
27
Single base instability is promoted in vulvar lichen sclerosus. (17554370)
2007
28
Vulvar melanoma in a 10-year-old girl in association with lichen sclerosus. (16427997)
2006
29
Rapid onset of acute carcinoma of the glans penis arising three years after a lichen sclerosus. (16280309)
2005
30
Lichen sclerosus. (16004624)
2005
31
Lichen sclerosus in children. (15763776)
2004
32
Development of multifocal squamous cell carcinoma in lichen sclerosus et atrophicus of the penis associated to HCV hepatitis. (14871263)
2004
33
Vasculitis in lichen sclerosus: an under recognized feature? (15330801)
2004
34
Genital lichen sclerosus, squamous cell carcinoma and circumcision. (12786863)
2003
35
The role of angiogenesis in vulvar cancer, vulvar intraepithelial neoplasia, and vulvar lichen sclerosus as determined by microvessel density analysis. (12713988)
2003
36
TP53 mutations in vulval lichen sclerosus adjacent to squamous cell carcinoma of the vulva. (14676802)
2003
37
Overexpression of wild-type p53 in lichen sclerosus adjacent to human papillomavirus-negative vulvar cancer. (12445188)
2002
38
Perineoplasty for the treatment of introital stenosis related to vulvar lichen sclerosus. (11810083)
2002
39
Genital lichen sclerosus associated with incontinence. (12521711)
2002
40
Chronic borreliosis presenting with morphea- and lichen sclerosus et atrophicus-like cutaneous lesions. a case report. (11455165)
2001
41
Nail dystrophy due to lichen sclerosus? (11678877)
2001
42
Concordant p53 and mdm-2 protein expression in vulvar squamous cell carcinoma and adjacent lichen sclerosus. (11396633)
2001
43
Lichen sclerosus of the vulva. Long-term steroid maintenance therapy. (10442326)
1999
44
Does lichen sclerosus play a central role in the pathogenesis of human papillomavirus negative vulvar squamous cell carcinoma? The itch-scratch-lichen sclerosus hypothesis. (11240748)
1999
45
Advances in vulvar disease: lichen sclerosus et atrophicus et al. (1739579)
1992
46
Vulvar cicatricial pemphigoid as a lichen sclerosus imitator. A case report. (1619612)
1992
47
Treatment of localized scleroderma and lichen sclerosus with etretinate. (6203311)
1984
48
Balanitis xerotica obliterans manifesting on stump of amputated penis; report of an unusual case and remarks on the nature of lichen sclerosus et atrophicus. (13636433)
1959
49
50

Variations for Lichen Sclerosus

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Expression for genes affiliated with Lichen Sclerosus

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Search GEO for disease gene expression data for Lichen Sclerosus.

Pathways for genes affiliated with Lichen Sclerosus

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GO Terms for genes affiliated with Lichen Sclerosus

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Cellular components related to Lichen Sclerosus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1trans-Golgi network membraneGO:00325889.0HLA-DQB1, HLA-DRB1
2ER to Golgi transport vesicle membraneGO:00125078.7HLA-DQB1, HLA-DRB1

Biological processes related to Lichen Sclerosus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell-matrix adhesionGO:00071609.6CD44, COL17A1
2immunoglobulin production involved in immunoglobulin mediated immune responseGO:00023819.5HLA-DQB1, HLA-DRB1
3positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.5CD44, TP53
4antigen processing and presentationGO:00198829.0HLA-DQB1, HLA-DRB1

Sources for Lichen Sclerosus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet