MCID: LDD003
MIFTS: 19

Liddle Syndrome, Scnn1b-Related malady

Categories: Genetic diseases, Rare diseases, Cardiovascular diseases, Nephrological diseases

Aliases & Classifications for Liddle Syndrome, Scnn1b-Related

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Aliases & Descriptions for Liddle Syndrome, Scnn1b-Related:

Name: Liddle Syndrome, Scnn1b-Related 24
Pseudoprimary Hyperaldosteronism 68
 
Pseudoaldosteronism 24
Liddle Syndrome 68

Classifications:



Summaries for Liddle Syndrome, Scnn1b-Related

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MalaCards based summary: Liddle Syndrome, Scnn1b-Related, also known as pseudoprimary hyperaldosteronism, is related to liddle syndrome and gitelman syndrome. An important gene associated with Liddle Syndrome, Scnn1b-Related is SCNN1B (Sodium Channel Epithelial 1 Beta Subunit), and among its related pathways are Ion channel transport and Neuropathic Pain-Signaling in Dorsal Horn Neurons.

Related Diseases for Liddle Syndrome, Scnn1b-Related

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Graphical network of diseases related to Liddle Syndrome, Scnn1b-Related:



Diseases related to liddle syndrome, scnn1b-related

Symptoms & Phenotypes for Liddle Syndrome, Scnn1b-Related

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Drugs & Therapeutics for Liddle Syndrome, Scnn1b-Related

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Liddle Syndrome, Scnn1b-Related

Genetic Tests for Liddle Syndrome, Scnn1b-Related

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Genetic tests related to Liddle Syndrome, Scnn1b-Related:

id Genetic test Affiliating Genes
1 Liddle Syndrome, Scnn1b-Related24 SCNN1B

Anatomical Context for Liddle Syndrome, Scnn1b-Related

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Publications for Liddle Syndrome, Scnn1b-Related

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Variations for Liddle Syndrome, Scnn1b-Related

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Expression for genes affiliated with Liddle Syndrome, Scnn1b-Related

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Search GEO for disease gene expression data for Liddle Syndrome, Scnn1b-Related.

Pathways for genes affiliated with Liddle Syndrome, Scnn1b-Related

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GO Terms for genes affiliated with Liddle Syndrome, Scnn1b-Related

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Cellular components related to Liddle Syndrome, Scnn1b-Related according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1apical plasma membraneGO:00163249.7SCNN1B, SCNN1G
2external side of plasma membraneGO:00098979.3SCNN1B, SCNN1G
3sodium channel complexGO:00347069.1SCNN1B, SCNN1G

Biological processes related to Liddle Syndrome, Scnn1b-Related according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1excretionGO:00075889.9SCNN1B, SCNN1G
2ion transmembrane transportGO:00342209.9SCNN1B, SCNN1G
3ion transportGO:00068119.8SCNN1B, SCNN1G
4multicellular organismal water homeostasisGO:00508919.8SCNN1B, SCNN1G
5response to stimulusGO:00508969.7SCNN1B, SCNN1G
6sensory perception of tasteGO:00509099.7SCNN1B, SCNN1G
7sodium ion homeostasisGO:00550789.7SCNN1B, SCNN1G
8sodium ion transmembrane transportGO:00357259.7SCNN1B, SCNN1G
9sodium ion transportGO:00068149.1SCNN1B, SCNN1G

Molecular functions related to Liddle Syndrome, Scnn1b-Related according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ligand-gated sodium channel activityGO:00152809.5SCNN1B, SCNN1G
2WW domain bindingGO:00506999.1SCNN1B, SCNN1G

Sources for Liddle Syndrome, Scnn1b-Related

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet