MCID: LMB012
MIFTS: 18

Limb Dystonia malady

Rare diseases category

Aliases & Classifications for Limb Dystonia

About this section
Sources:
41NIH Rare Diseases, 47Orphanet, 26ICD10 via Orphanet
See all sources

Limb Dystonia, Aliases & Descriptions:

Name: Limb Dystonia 41 47


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


External Ids:

Orphanet47 93957
ICD10 via Orphanet26 G24.8

Summaries for Limb Dystonia

About this section


NIH Rare Diseases:41 Limb dystonia is characterized by excessive pulling of the muscles of a limb, such as the hand or foot. the arm or leg might also be involved. specific symptoms depend on the combinations of muscles involved and how hard each one is pulling. mild forms may be expressed as stiffness or soreness of a limb; more moderate forms are characterized by unwanted movements or postures; and in severe forms, abnormal postures may become fixed. common examples of limb dystonia include writer's cramp and musician's dystonia. in most cases, the cause of limb dystonia remains unknown. treatment is challenging. botulinum toxin injection, oral medications, and physical therapy may help some patients. last updated: 8/31/2014

MalaCards based summary: Limb Dystonia is related to blepharospasm and dystonia. An important gene associated with Limb Dystonia is TIMM8A (translocase of inner mitochondrial membrane 8 homolog A (yeast)). The compound tyrosine have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe.

Related Diseases for Limb Dystonia

About this section

Graphical network of the top 20 diseases related to Limb Dystonia:



Diseases related to limb dystonia

Symptoms for Limb Dystonia

About this section

Drugs & Therapeutics for Limb Dystonia

About this section

Drug clinical trials:

Search ClinicalTrials for Limb Dystonia

Search NIH Clinical Center for Limb Dystonia

Genetic Tests for Limb Dystonia

About this section

Anatomical Context for Limb Dystonia

About this section

MalaCards organs/tissues related to Limb Dystonia:

31
Temporal lobe

Animal Models for Limb Dystonia or affiliated genes

About this section

Publications for Limb Dystonia

About this section

Articles related to Limb Dystonia:

(show all 27)
idTitleAuthorsYear
1
Isolated limb dystonia as presenting feature of Parkin disease. (24659796)
2014
2
Levodopa Responsiveness in Adult-onset Lower Limb Dystonia is Associated with the Development of Parkinson's Disease. (23610745)
2013
3
Psychogenic tetraparesis and bilateral upper limb dystonia, regressive under short propofol-induced sedation and during hepatic encephalopathy. (22902089)
2012
4
Drummer's lower limb dystonia. (22160433)
2012
5
The broadening application of chemodenervation in X-linked dystonia-parkinsonism (Part I): muscle afferent block versus botulinum toxin-A in cervical and limb dystonias. (21244305)
2011
6
Successful bilateral pallidal stimulation in a patient with isolated lower limb dystonia coexistent with Langerhans cell histiocytosis and coeliac disease. (22127949)
2011
7
Focal limb dystonia. (20590804)
2010
8
Clinical improvement of secondary focal limb dystonia in neurodegenerative disease following a five-day lidocaine infusion: a case report. (19013587)
2009
9
Blepharospasm and limb dystonia caused by Mohr-Tranebjaerg syndrome with a novel splice-site mutation in the deafness/dystonia peptide gene. (17534980)
2007
10
Restoring balance in focal limb dystonia with botulinum toxin. (18033603)
2007
11
Adult-onset primary lower limb dystonia. (16456826)
2006
12
Patterns of EMG-EMG coherence in limb dystonia. (15254933)
2004
13
Does sex influence age at onset in cranial-cervical and upper limb dystonia? (12531967)
2003
14
Ictal limb dystonia in temporal lobe epilepsy. an invasive video-EEG finding. (14641508)
2003
15
Progressive supranuclear palsy with asymmetric tau pathology presenting with unilateral limb dystonia. (12111365)
2002
16
Accuracy of muscle localization without EMG: implications for treatment of limb dystonia. (11889247)
2002
17
Focal limb dystonia in a patient with a cerebellar mass. (11448302)
2001
18
Posthemiplegic focal limb dystonia: a report of two cases. (9637205)
1998
19
Delayed onset limb dystonia following electric injury. (18591086)
1998
20
An aggressive approach to limb dystonia: a case report. (9596405)
1998
21
Abnormal motor unit synchronization of antagonist muscles underlies pathological co-contraction in upper limb dystonia. (9619186)
1998
22
Treatment of upper limb dystonia with botulinum toxin. (18638853)
1996
23
Upper-limb dystonia secondary to a midbrain hemorrhage. (8771076)
1996
24
Physiological effects produced by botulinum toxin treatment of upper limb dystonia. Changes in reciprocal inhibition between forearm muscles. (7600096)
1995
25
Bilateral limb dystonia due to chronic subdural hematoma. (2209675)
1990
26
Apparent G syndrome presenting as neck and upper limb dystonia and severe gastroesophageal reflux. (3425612)
1987
27
Limb dystonia in progressive supranuclear palsy. (3627456)
1987

Variations for Limb Dystonia

About this section

Expression for genes affiliated with Limb Dystonia

About this section
Search GEO for disease gene expression data for Limb Dystonia.

Pathways for genes affiliated with Limb Dystonia

About this section

Compounds for genes affiliated with Limb Dystonia

About this section
Sources:
43Novoseek
See all sources

Compounds related to Limb Dystonia according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1tyrosine439.1TOR1A, TIMM8A

GO Terms for genes affiliated with Limb Dystonia

About this section

Products for genes affiliated with Limb Dystonia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Limb Dystonia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet