LMS
MCID: LMB008
MIFTS: 28

Limb-Mammary Syndrome (LMS) malady

Eye diseases, Reproductive diseases, Bone diseases, Skin diseases, Fetal diseases categories

Summaries for Limb-Mammary Syndrome

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63Wikipedia, 46OMIM, 32MalaCards
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Wikipedia:63 Limb–mammary syndrome is a cutaneous condition characterized by p63 mutations. more...

MalaCards: Limb-Mammary Syndrome, also known as LMS, is related to leiomyosarcoma and adult syndrome. An important gene associated with Limb-Mammary Syndrome is TP63 (tumor protein p63). Affiliated tissues include eye, bone and skin.

Description from OMIM:46 603543

Aliases & Classifications for Limb-Mammary Syndrome

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Sources:
42NIH Rare Diseases, 48Orphanet, 20GeneTests, 22GTR, 46OMIM, 44Novoseek, 60UMLS, 35MESH via Orphanet, 61UMLS via Orphanet
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Classifications:



Characteristics (Orphanet epidemiological data):

48
limb-mammary syndrome:
Inheritance: Autosomal dominant; Prevalence: <1/1000000; Age of onset: Neonatal/infancy


Aliases & Descriptions:

limb-mammary syndrome 42 20 22 46 44 48 60
lms 42 48
mammary hypoplasia, ectrodactyly, and other hand/foot anomalies 42


External Ids:

OMIM46 603543
MESH via Orphanet35 C535903
UMLS via Orphanet61 C1863753

Related Diseases for Limb-Mammary Syndrome

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17GeneCards, 18GeneDecks
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Diseases related to Limb-Mammary Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 16)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyosarcoma10.2
2adult syndrome10.1
3bardet-biedl syndrome9.9
4smooth muscle tumor9.9
5akinetopsia9.9
6lactose intolerance9.9
7cleft palate9.9
8endometrial stromal sarcoma9.9
9osteogenesis imperfecta9.9
10adenoid cystic carcinoma9.9
11adenoiditis9.9
12leiomyoma9.9
13sarcoma9.9
14uterus leiomyosarcoma9.9
15lateral meningocele syndrome9.9
16lymphatic malformation9.9

Graphical network of diseases related to Limb-Mammary Syndrome:



Diseases related to limb-mammary syndrome

Clinical Features for Limb-Mammary Syndrome

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46OMIM
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Clinical features from OMIM:

603543

Clinical synopsis from OMIM:

603543

Drugs & Therapeutics for Limb-Mammary Syndrome

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Limb-Mammary Syndrome

Drug clinical trials:

Search ClinicalTrials for Limb-Mammary Syndrome

Search NIH Clinical Center for Limb-Mammary Syndrome

Search CenterWatch for Limb-Mammary Syndrome

Genetic Tests for Limb-Mammary Syndrome

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20GeneTests, 22GTR
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Genetic tests related to Limb-Mammary Syndrome:

id Genetic test Affiliating Genes
1 Limb-Mammary Syndrome20 22 TP63

Anatomical Context for Limb-Mammary Syndrome

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32MalaCards
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MalaCards organs/tissues related to Limb-Mammary Syndrome:

32
Eye, Bone, Skin

Animal Models for Limb-Mammary Syndrome or affiliated genes

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Publications for Limb-Mammary Syndrome

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Genetic Variations for Limb-Mammary Syndrome

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Expression for genes affiliated with Limb-Mammary Syndrome

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Limb-Mammary Syndrome

Search GEO for disease gene expression data for Limb-Mammary Syndrome.

Pathways for genes affiliated with Limb-Mammary Syndrome

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Compounds for genes affiliated with Limb-Mammary Syndrome

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GO Terms for genes affiliated with Limb-Mammary Syndrome

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Products for genes affiliated with Limb-Mammary Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Limb-Mammary Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet