Aliases & Classifications for Limbic Encephalitis

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Sources:
45NIH Rare Diseases, 47Novoseek, 65UMLS
See all sources

Aliases & Descriptions for Limbic Encephalitis:

Name: Limbic Encephalitis 45 47 65


Classifications:



Summaries for Limbic Encephalitis

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NIH Rare Diseases:45 Limbic encephalitis is a condition marked by the inflammation of the limbic system and other parts of the brain. the cardinal sign of limbic encephalitis is a severe impairment of short-term memory; however, symptoms may also include confusion, psychiatric symptoms, and seizures. the symptoms typically develop over a few weeks or months, but they may evolve over a few days. delayed diagnosis is common, but improvements are being made to assist in early detection. early diagnosis may improve the outcome of limbic encephalitis. last updated: 6/8/2009

MalaCards based summary: Limbic Encephalitis is related to paraneoplastic neurologic disorders and encephalitis. An important gene associated with Limbic Encephalitis is GAD1 (Glutamate Decarboxylase 1 (Brain, 67kDa)), and among its related pathways are Hypothetical Network for Drug Addiction and Synthesis and interconversion of nucleotide di- and triphosphates. Affiliated tissues include brain, lung and temporal lobe, and related mouse phenotypes are nervous system and behavior/neurological.

Wikipedia:68 Limbic encephalitis is a form of encephalitis, a disease characterised by inflammation of the brain.... more...

Related Diseases for Limbic Encephalitis

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Diseases related to Limbic Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idRelated DiseaseScoreTop Affiliating Genes
1paraneoplastic neurologic disorders30.5AMPH, ELAVL3
2encephalitis11.5
3non-herpetic acute limbic encephalitis10.7
4neuronitis10.7
5teratoma10.7
6lung cancer10.7
7thymoma10.7
8status epilepticus10.6
9relapsing polychondritis10.6
10temporal lobe epilepsy10.5
11dementia10.5
12limbic encephalitis with dpp6 antibodies10.5
13hodgkin lymphoma10.4
14testicular cancer10.4
15classic paraneoplastic limbic encephalitis10.4
16limbic encephalitis with lgi1 antibodies10.4
17limbic encephalitis with ncmags antibodies10.4
18posttransplant acute limbic encephalitis10.4
19limbic encephalitis with nmda receptor antibodies10.4
20breast cancer10.4
21adenocarcinoma10.4
22prostatitis10.4
23cerebellar degeneration10.4
24encephalopathy10.4
25paraneoplastic syndromes10.4
26limbic encephalitis with caspr2 antibodies10.4
27prostate cancer10.3
28renal cell carcinoma10.3
29cerebellar ataxia10.3
30creutzfeldt-jakob disease10.3
31leukemia10.3
32myasthenia gravis10.3
33viral encephalitis10.3
34anterograde amnesia10.3
35herpes simplex10.3
36ovarian cancer10.3
37neurosyphilis10.3
38paraneoplastic cerebellar degeneration10.3
39ataxia10.3
40myoclonus10.3
41neuroblastoma10.1
42systemic lupus erythematosus10.1
43aplastic anemia10.1
44neuropathy, hereditary sensory and autonomic, type ii10.1
45pancreatic cancer10.1
46chronic lymphocytic leukemia10.1
47hematopoietic stem cell transplantation10.1
48neuromyelitis optica10.1
49primary biliary cirrhosis10.1
50small cell carcinoma10.1

Graphical network of the top 20 diseases related to Limbic Encephalitis:



Diseases related to limbic encephalitis

Symptoms for Limbic Encephalitis

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Drugs & Therapeutics for Limbic Encephalitis

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Drugs for Limbic Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tacrolimusapproved, investigational992104987-11-3445643, 439492, 445647, 439492, 445647
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
8-DEETHYL-8-[but-3-enyl]-ascomycin
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
FR900506
 
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
Hecoria
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus Hydrate
Tacrolimus anhydrous
Tacrolimus hydrate
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
2
Prednisoneapproved120853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone

Interventional clinical trials:

idNameStatusNCT IDPhase
1IVIG Treatment for Refractory Immune-Related Adult EpilepsyTerminatedNCT01545518Phase 2
2Immunotherapy of the Paraneoplastic SyndromesCompletedNCT00378326

Search NIH Clinical Center for Limbic Encephalitis

Genetic Tests for Limbic Encephalitis

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Anatomical Context for Limbic Encephalitis

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MalaCards organs/tissues related to Limbic Encephalitis:

33
Brain, Lung, Temporal lobe, Bone, Bone marrow, Prostate, Breast

Animal Models for Limbic Encephalitis or affiliated genes

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MGI Mouse Phenotypes related to Limbic Encephalitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036316.9ADAM22, AMPH, BRSK2, ELAVL3, GAD1, GAD2
2MP:00053866.6ADAM22, AMPH, BRSK2, ELAVL3, GAD1, GAD2

Publications for Limbic Encephalitis

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Articles related to Limbic Encephalitis:

(show top 50)    (show all 415)
idTitleAuthorsYear
1
A Reversible Rapidly Progressive Cognitive Disorder: Limbic Encephalitis with Leucine-Rich Glioma Inactivated-1 Protein Antibody and an Ectopic Adrenocorticotropic Hormone Syndrome. (26189861)
2015
2
Uncommon 18F-FDG-PET/CT findings in patients affected by limbic encephalitis: hyper-hypometabolic pattern with double antibody positivity and migrating foci of hypermetabolism. (25487436)
2015
3
Limbic Encephalitis Diagnosed With 18F-FDG PET/CT. (26571448)
2015
4
Limbic encephalitis associated with relapsing polychondritis responded to infliximab and maintained its condition without recurrence after discontinuation: a case report and review of the literature. (25741046)
2014
5
Limbic encephalitis due to GABAB and AMPA receptor antibodies: a case series. (25300449)
2014
6
Mature ovarian teratoma-associated limbic encephalitis. (25093683)
2014
7
Autoimmune limbic encephalitis and anesthesia. (24104946)
2013
8
Limbic encephalitis: a clinical-radiological comparison between herpetic and autoimmune etiologies. (23941332)
2013
9
Correlative imaging with (18)F-FDG PET/CT and MRI in paraneoplastic limbic encephalitis. (23531769)
2013
10
Voltage-gated potassium channel antibody paraneoplastic limbic encephalitis associated with acute myeloid leukemia. (23898271)
2013
11
Limbic Encephalitis Associated With Elevated Antithyroid Antibodies. (23520363)
2013
12
Autoimmune limbic encephalitis presenting as relapsing psychosis. (23997078)
2013
13
The diagnosis and treatment of limbic encephalitis. (22713136)
2012
14
Surgical control of limbic encephalitis associated with LGI1 antibodies. (22940785)
2012
15
Two different 18F-FDG brain PET metabolic patterns in autoimmune limbic encephalitis. (22889795)
2012
16
Cord-blood hematopoietic stem cell transplantA confers an increased risk for human herpesvirus-6-associated acute limbic encephalitis: aA cohort analysis. (22564265)
2012
17
Proposition: limbic encephalitis may represent limbic status epilepticus. A review of clinical and EEG characteristics. (22459869)
2012
18
A boy with non-herpes simplex acute limbic encephalitis and antiglutamate receptor antibodies. (22084613)
2011
19
Continuous muscle activity, Morvan's syndrome and limbic encephalitis: ionic or non ionic disorders? (21842591)
2011
20
Autoimmune Limbic Encephalitis With GAD Antibodies. (23983853)
2011
21
Recognition of faciobrachial dystonic seizures allowing early intervention with and prevention of development of full-blown limbic encephalitis. (22319790)
2011
22
Steroid-responsive recurrent limbic encephalitis associated with small cell lung cancer and neuropil antibodies. (21748934)
2011
23
An effective immunotherapy regimen for VGKC antibody-positive limbic encephalitis. (20660916)
2010
24
Non-paraneoplastic limbic encephalitis associated with NMDAR and VGKC antibodies. (20667865)
2010
25
Limbic encephalitis associated with systemic lupus erythematosus. (19850655)
2009
26
Autoantibodies to glutamate receptor GluRepsilon2 in a patient with limbic encephalitis associated with relapsing polychondritis. (19716567)
2009
27
Voltage-gated potassium channel-associated limbic encephalitis in the West of Scotland: case reports and literature review. (20034278)
2009
28
An autopsy case with non-herpetic acute limbic encephalitis (NHALE). (18282167)
2008
29
Paraneoplastic limbic encephalitis as a cause of new onset of seizures in a patient with non-small cell lung carcinoma: a case report. (18700972)
2008
30
Limbic encephalitis as presentation of a SAP deficiency. (17620557)
2007
31
Post-transplant acute limbic encephalitis: clinical features and relationship to HHV6. (17620548)
2007
32
Complex partial status epilepticus in paraneoplastic limbic encephalitis. (17844948)
2007
33
Limbic encephalitis--an uncommon presentation of systemic malignancy. (18173029)
2007
34
Limbic encephalitis: extension of the diagnostic armamentarium. (17018560)
2007
35
Anti-Hu-associated paraneoplastic limbic encephalitis presenting as rapidly progressive non-convulsive status epilepticus. (16631204)
2006
36
Reversible paraneoplastic limbic encephalitis caused by a benign ovarian teratoma: report of a case and review of literatures. (16944314)
2006
37
Electroconvulsive therapy in a pediatric patient with malignant catatonia and paraneoplastic limbic encephalitis. (17143159)
2006
38
Paraneoplastic limbic encephalitis. (15708228)
2005
39
Neurosyphilis and paraneoplastic limbic encephalitis: important differential diagnoses. (15789128)
2005
40
Treatment-responsive limbic encephalitis identified by neuropil antibodies: MRI and PET correlates. (15888538)
2005
41
A pre-senile case of limbic encephalitis and cerebellar degeneration, with subacute onset of progressive dementia. (15673963)
2004
42
Non-herpetic acute limbic encephalitis: a new subgroup of limbic encephalitis? (15168784)
2004
43
Resolution of limbic encephalitis with detection and treatment of lung cancer: clinical-radiological correlation. (12499067)
2003
44
Asessment of paraneoplastic limbic encephalitis in testicular cancer. (12846502)
2003
45
Paraneoplastic limbic encephalitis masquerading as chronic behavioural disturbance in an adolescent girl. (12801123)
2003
46
Hypermetabolism of the medial temporal lobe in limbic encephalitis on (18)FDG-PET scan: a case report. (11306867)
2001
47
Varicella-zoster virus limbic encephalitis in an immunocompromised patient. (11728054)
2001
48
Paraneoplastic limbic encephalitis should not be overlooked as a possible cause of delirium in cancer patients. (11025799)
2000
49
Limbic encephalitis. A rare presentation of the small-cell lung carcinoma. (2553530)
1989
50
Small-cell lung cancer and limbic encephalitis. (6283978)
1982

Variations for Limbic Encephalitis

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Expression for genes affiliated with Limbic Encephalitis

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Search GEO for disease gene expression data for Limbic Encephalitis.

Pathways for genes affiliated with Limbic Encephalitis

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GO Terms for genes affiliated with Limbic Encephalitis

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Cellular components related to Limbic Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1clathrin-sculpted gamma-aminobutyric acid transport vesicle membraneGO:006120210.3GAD1, GAD2
2synaptic vesicleGO:00080219.9AMPH, GRIA1, GRIN2B
3postsynaptic densityGO:00140699.3GRIA1, GRIN2B, PPP1R9B
4cell junctionGO:00300549.0AMPH, GAD2, GRIA1, GRIN2B, LGI1

Biological processes related to Limbic Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glutamate decarboxylation to succinateGO:000654010.5GAD1, GAD2
2ionotropic glutamate receptor signaling pathwayGO:003523510.1GRIA1, GRIN2B
3neurotransmitter biosynthetic processGO:004213610.0GAD1, GAD2
4carboxylic acid metabolic processGO:00197529.9GAD1, GAD2
5nucleobase-containing small molecule interconversionGO:00159499.9AK5, GSR
6synaptic transmissionGO:00072689.0AMPH, GAD1, GAD2, GRIA1, GRIN2B

Molecular functions related to Limbic Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glutamate decarboxylase activityGO:000435110.1GAD1, GAD2
2ionotropic glutamate receptor activityGO:000497010.0GRIA1, GRIN2B
3extracellular-glutamate-gated ion channel activityGO:000523410.0GRIA1, GRIN2B
4carboxy-lyase activityGO:00168319.8GAD1, GAD2

Sources for Limbic Encephalitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet