LWNH
MCID: LNR007
MIFTS: 17

Linear and Whorled Nevoid Hypermelanosis (LWNH) malady

Skin diseases category

Summaries for Linear and Whorled Nevoid Hypermelanosis

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Sources:
42NIH Rare Diseases, 63Wikipedia, 46OMIM, 32MalaCards
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NIH Rare Diseases:42 Linear and whorled nevoid hypermelanosis is a skin condition characterized by swirling streaks of hyperpigmented (darkened) skin. the hyperpigmentation follows the lines of blashko. the hyperpigmentation often occurs alone, but additional symptoms have been described in individual cases. its occurrence is nearly always sporadic. the cause of linear and whorled nevoid hypermelanosis is not known. last updated: 3/18/2013

MalaCards: Linear and Whorled Nevoid Hypermelanosis, also known as nevoid hypermelanosis, linear and whorled, is related to ichthyosis vulgaris. An important gene associated with Linear and Whorled Nevoid Hypermelanosis is IKBKG (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma). Affiliated tissues include skin.

Wikipedia:63 Linear and whorled nevoid hypermelanosis (also known as \"Linear nevoid hyperpigmentation,\"... more...

Description from OMIM:46 614323

Aliases & Classifications for Linear and Whorled Nevoid Hypermelanosis

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Sources:
42NIH Rare Diseases, 48Orphanet, 46OMIM, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

linear and whorled nevoid hypermelanosis 42 48 46
nevoid hypermelanosis, linear and whorled 42
reticulate hyperpigmentation of iijima 42
linear and whorled hypermelanosis 42
zebra-like hyperpigmentation 42
lwnh 42


External Ids:

OMIM46 614323
ICD10 via Orphanet26 L81.4
SNOMED-CT via Orphanet57 403803002
UMLS via Orphanet61 C1304501

Related Diseases for Linear and Whorled Nevoid Hypermelanosis

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17GeneCards, 18GeneDecks
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Diseases related to Linear and Whorled Nevoid Hypermelanosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1ichthyosis vulgaris10.5

Clinical Features for Linear and Whorled Nevoid Hypermelanosis

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46OMIM
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Clinical features from OMIM:

614323

Clinical synopsis from OMIM:

614323

Drugs & Therapeutics for Linear and Whorled Nevoid Hypermelanosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Linear and Whorled Nevoid Hypermelanosis

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Genetic Tests for Linear and Whorled Nevoid Hypermelanosis

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Anatomical Context for Linear and Whorled Nevoid Hypermelanosis

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32MalaCards
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MalaCards organs/tissues related to Linear and Whorled Nevoid Hypermelanosis:

32
Skin

Animal Models for Linear and Whorled Nevoid Hypermelanosis or affiliated genes

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Publications for Linear and Whorled Nevoid Hypermelanosis

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Genetic Variations for Linear and Whorled Nevoid Hypermelanosis

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Expression for genes affiliated with Linear and Whorled Nevoid Hypermelanosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Linear and Whorled Nevoid Hypermelanosis

Search GEO for disease gene expression data for Linear and Whorled Nevoid Hypermelanosis.

Pathways for genes affiliated with Linear and Whorled Nevoid Hypermelanosis

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Compounds for genes affiliated with Linear and Whorled Nevoid Hypermelanosis

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GO Terms for genes affiliated with Linear and Whorled Nevoid Hypermelanosis

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Products for genes affiliated with Linear and Whorled Nevoid Hypermelanosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Linear and Whorled Nevoid Hypermelanosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet