MCID: LNT001
MIFTS: 30

Linitis Plastica malady

Gastrointestinal diseases category

Summaries for Linitis Plastica

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Wikipedia:65 Linitis plastica, also known as Brinton\'s disease or leather bottle stomach, is a morphological variant... more...

MalaCards based summary: Linitis Plastica, also known as leather-bottle stomach, is related to gastric linitis plastica and adenocarcinoma. An important gene associated with Linitis Plastica is PRSS2 (protease, serine, 2 (trypsin 2)). The compounds calcium and cysteine have been mentioned in the context of this disorder. Affiliated tissues include colon, breast and bone.

Aliases & Classifications for Linitis Plastica

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Linitis Plastica, Aliases & Descriptions:

Name: Linitis Plastica 10 62
 
Leather-Bottle Stomach 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology10 DOID:4023
NCIt40 C3190
SNOMED-CT57 37995004, 307594007
MeSH35 D008039

Related Diseases for Linitis Plastica

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Diseases related to Linitis Plastica via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 26)
idRelated DiseaseScoreTop Affiliating Genes
1gastric linitis plastica10.9
2adenocarcinoma10.7
3colitis10.6
4breast cancer10.5
5ulcerative colitis10.5
6gastritis10.5
7signet ring cell adenocarcinoma10.4
8gastric adenocarcinoma10.4
9gastric diffuse adenocarcinoma10.4
10peritonitis10.4
11sarcoma10.4
12syphilis10.4
13obesity10.3
14hodgkin lymphoma10.3
15crohn's disease10.3
16morbid obesity10.3
17crohn's colitis10.3
18gastric lymphoma10.3
19situs inversus10.3
20macrocytic anemia10.3
21prostatitis10.3
22transitional cell carcinoma10.3
23tuberculosis10.3
24gastric outlet obstruction10.3
25colorectal cancer10.0CEACAM5, PRSS2
26cork-handlers' disease10.0CEACAM5, PRSS2

Graphical network of the top 20 diseases related to Linitis Plastica:



Diseases related to linitis plastica

Symptoms for Linitis Plastica

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Drugs & Therapeutics for Linitis Plastica

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Drug clinical trials:

Search ClinicalTrials for Linitis Plastica

Search NIH Clinical Center for Linitis Plastica

Genetic Tests for Linitis Plastica

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Anatomical Context for Linitis Plastica

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MalaCards organs/tissues related to Linitis Plastica:

33
Colon, Breast, Bone, Lymph node, Skin, Prostate, Appendix

Animal Models for Linitis Plastica or affiliated genes

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Publications for Linitis Plastica

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Articles related to Linitis Plastica:

(show top 50)    (show all 170)
idTitleAuthorsYear
1
Recurrent bladder cancer presenting as rectal linitis plastica. (25734804)
2015
2
Primary linitis plastica of the entire colon in a background of ulcerative colitis: a case report. (25649787)
2015
3
Linitis Plastica of the Rectum As a Clinical Presentation of Metastatic Lobular Carcinoma of the Breast. (24982453)
2014
4
Managing Gastric Linitis Plastica: Keep the scalpel sheathed. (23984032)
2013
5
Endoscopic ultrasonographic features of gastric linitis plastica in fifty-five Chinese patients. (24009205)
2013
6
Metastatic lobular breast cancer presenting as gastric linitis plastica. (21571246)
2011
7
Metastatic breast carcinoma simulating linitis plastica of the colon: report of a case. (21431489)
2011
8
Facing the challenge of managing linitis plastica--review of the literature. (20214236)
2009
9
Colorectal linitis plastica complicating chronic ulcerative colitis. (18798572)
2009
10
Linitis plastica of the rectum secondary to bladder carcinoma: a report of two cases and its MR features. (18796553)
2008
11
The number of metastatic lymph nodes is a significant risk factor for bone metastasis and poor outcome after surgery for linitis plastica-type gastric carcinoma. (18563480)
2008
12
Relatively small size linitis plastica of the stomach: multislice CT detection of tissue fibrosis. (17151892)
2007
13
TS-1 as first-line therapy for gastric linitis plastica: historical control study. (16702816)
2006
14
Cytologic diagnosis of gastric linitis plastica by endoscopic ultrasound guided fine-needle aspiration. (16511853)
2006
15
Linitis plastica due to gastric diverticulosis. (16140854)
2005
16
Gastric outlet obstruction secondary to linitis plastica of the stomach as shown on transabdominal sonography. (15292571)
2004
17
Gastrointestinal stromal tumour (GIST) masquerading as linitis plastica. (14717680)
2004
18
A new mutation of E-cadherin gene in familial gastric linitis plastica cancer with extra-digestive dissemination. (11434599)
2001
19
Linitis plastica presenting as malignant ascites. (11241451)
2001
20
Linitis plastica as the first indication of metastatic lobular carcinoma of the breast: case report and literature review. (10593250)
1999
21
Endoscopic ultrasonography in rectal linitis plastica. (9434221)
1997
22
Linitis plastica of the colon in ulcerative colitis. (9298379)
1997
23
Flow cytometry as a prognostic predictor in gastric linitis plastica. (8057648)
1994
24
Primary linitis plastica of the colon. (8224702)
1993
25
A case of linitis plastica of the rectum treated by pelvic exenteration after aggressive immunochemotherapy. (1498496)
1992
26
Kaposi's sarcoma presenting as linitis plastica. (1962631)
1991
27
Gastric linitis plastica metastatic to the uvea. (1751916)
1991
28
Linitis plastica of the alimentary tract and scrotum. (2153597)
1990
29
Primary linitis plastica of the descending colon: a case report. (2160554)
1990
30
Linitis plastica of the stomach and entire intestine. (3022171)
1986
31
Obstructive uropathy. An unusual presentation of primary linitis plastica of the colon. (2988885)
1985
32
Primary linitis plastica of the colon and rectum. Report of two cases. (6313308)
1983
33
Primary linitis plastica carcinoma of urinary bladder. (6312662)
1983
34
Primary signet ring cell adenocarcinoma of the bladder (linitis plastica of the bladder): report of a case and review of the literature. (6294348)
1982
35
Linitis plastica infiltrating the entire gut. (6285694)
1982
36
Linitis plastica in a 16-year-old. (171966)
1975
37
Primary linitis plastica carcinoma of the colon. (4370676)
1974
38
Gastric adenocarcinoma or linitis plastica in a dog. (4486933)
1973
39
Linitis plastica of the colon and rectum: report of two cases. (4337633)
1972
40
Primary linitis plastica of the rectum: report of two cases. (4334545)
1971
41
Linitis plastica carcinoma of the colon: report of a case. (4328825)
1971
42
Primary linitis plastica of the colon and rectum. (4319203)
1970
43
PRIMARY LINITIS PLASTICA CARCINOMA OF THE COLON. (14296754)
1965
44
LINITIS PLASTICA OR DIFFUSELY INFILTRATING TYPE OF CARCINOMA OF THE COLON. (14062258)
1963
45
Roentgenographic findings in an early case of linitis plastica. (14419028)
1960
46
Linitis plastica. (14406509)
1959
47
Linitis plastica carcinoma of the stomach with extensive metastases simulating a colonic lesion. (14906648)
1952
48
BENIGN HYPERTROPHY OF THE STOMACH AND LINITIS PLASTICA. (17865667)
1927
49
LINITIS PLASTICA. (17864459)
1921
50
VIII. Linitis Plastica (Cirrhosis of Stomach): With a Report of a Case Cured by Gastro-Jejunostomy. (17862763)
1911

Variations for Linitis Plastica

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Expression for genes affiliated with Linitis Plastica

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Search GEO for disease gene expression data for Linitis Plastica.

Pathways for genes affiliated with Linitis Plastica

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Compounds for genes affiliated with Linitis Plastica

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Sources:
45Novoseek, 51PharmGKB, 26HMDB, 13DrugBank
See all sources

Compounds related to Linitis Plastica according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium45 51 26 1312.1CEACAM5, PRSS2
2cysteine458.8CEACAM5, PRSS2

GO Terms for genes affiliated with Linitis Plastica

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Products for genes affiliated with Linitis Plastica

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Linitis Plastica

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet