MCID: LNT001
MIFTS: 29

Linitis Plastica malady

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Linitis Plastica

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Aliases & Descriptions for Linitis Plastica:

Name: Linitis Plastica 10 12 36 65
 
Leather-Bottle Stomach 10

Classifications:



External Ids:

Disease Ontology10 DOID:4023
MeSH36 D008039
SNOMED-CT59 307594007, 37995004
NCIt42 C3190
UMLS65 C0023743

Summaries for Linitis Plastica

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Wikipedia:68 Linitis plastica, also known as Brinton\'s disease or leather bottle stomach, is a morphological variant... more...

MalaCards based summary: Linitis Plastica, also known as leather-bottle stomach, is related to gastric linitis plastica and gastric diffuse adenocarcinoma. An important gene associated with Linitis Plastica is PRSS2 (Protease, Serine 2). Affiliated tissues include endothelial, lung and ovary, and related mouse phenotype tumorigenesis.

Related Diseases for Linitis Plastica

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Graphical network of the top 20 diseases related to Linitis Plastica:



Diseases related to linitis plastica

Symptoms for Linitis Plastica

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Drugs & Therapeutics for Linitis Plastica

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Drugs for Linitis Plastica (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CisplatinapprovedPhase 3254015663-27-184093, 441203, 2767
Synonyms:
(SP-4-1)-diamminedichloridoplatinum
(SP-4-1)-diamminedichloroplatinum
(SP-4-2)-diamminedichloridoplatinum
(SP-4-2)-diamminedichloroplatinum
Abiplatin
Biocisplatinum
Briplatin
CACP
CDDP
CHEBI:35852
CID441203
CPD0-1392
CPDC
CPDD
Carboquone
Cis Pt II
Cis-DDP
Cis-Diaminedichloroplatinum
Cis-Diamminedichloroplatinum
Cismaplat
Cisplatin
Cisplatine
Cisplatino
Cisplatinum
Cisplatyl
Citoplationo
DB00515
DDP
DDPT
Diamminedichloroplatinum
 
EU-0100918
Lederplatin
Neoplatin
Peyrone's chloride
Peyrone's salt
Plastin
Platamine
Platiblastin
Platidiam
Platinex
Platinol
Platinol-AQ
Platinol-aq
Platinoxan
Platinum Ammine Chloride
Platinum Ammonium Chloride
Platinum Diamine Dichloride
Randa
Trans-DDP
Trans-Diaminedichloroplatinum
Trans-Diamminedichloroplatinum
Trans-Dichlorodiammine Platinum
Trans-Platinumdiammine Dichloride
cis-DDP
cis-Diamminedichloroplatinum
cis-Dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
cis-diamminedichloridoplatinum(II)
cis-diamminedichloroplatinum(II)
nchembio773-comp1
trans-diamminedichloridoplatinum(II)
2
s 1 (combination)Phase 3325
Synonyms:
 
Gimeracil / oteracil / tegafur
TS 1

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Trial of Neoadjuvant TS-1 and Cisplatin for Type 4 and Large Type 3 Gastric CancerRecruitingNCT00252161Phase 3
2A Phase II Study to Evaluate Efficacy and Safety of Dovitinib (TKI258) in Advanced Scirrhous Gastric Carcinoma PatientsCompletedNCT01576380Phase 2

Search NIH Clinical Center for Linitis Plastica


Cochrane evidence based reviews: linitis plastica

Genetic Tests for Linitis Plastica

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Anatomical Context for Linitis Plastica

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MalaCards organs/tissues related to Linitis Plastica:

33
Endothelial, Lung, Ovary, T cells, Monocytes, Prostate, Heart

Animal Models for Linitis Plastica or affiliated genes

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MGI Mouse Phenotypes related to Linitis Plastica:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.0CDH1, PKM, PSCA

Publications for Linitis Plastica

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Articles related to Linitis Plastica:

(show top 49)    (show all 174)
idTitleAuthorsYear
1
Subfactors of oppositional defiant disorder: converging evidence from structural and latent class analyses. (25907358)
2015
2
Expression profiles of MYC protein and MYC gene rearrangement in lymphomas. (25581730)
2015
3
Gastrointestinal Erdheim-Chester disease. (24908861)
2014
4
Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway. (24885567)
2014
5
Rheumatic manifestations in inflammatory bowel disease. (23774109)
2014
6
On the Origin of Pediatric Nonalcoholic Fatty Liver Disease. (25373858)
2014
7
GABRA2 markers moderate the subjective effects of alcohol. (22501025)
2013
8
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor. (23403292)
2013
9
Simultaneous impairment of intracranial and peripheral artery vasoreactivity in CADASIL patients. (22179564)
2012
10
High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus. (21548924)
2011
11
Efficacy and safety of treatments for refractory generalized anxiety disorder: a systematic review. (21088608)
2011
12
Long-term outcomes after hepaticojejunostomy for choledochal cyst: a 10- to 27-year follow-up. (20152355)
2010
13
Sporadic hemiplegic migraine in children: a report of two new cases. (20739815)
2010
14
The effects of obesity and HER-2 polymorphisms as risk factors for endometrial cancer in Korean women. (19438491)
2009
15
Neurological manifestations of acute intermittent porphyria. (19268005)
2009
16
Histological, immunohistochemical and biological data in assessing interstitial fibrosis in patients with chronic glomerulonephritis. (18155753)
2008
17
Primary malignant fibrous histiocytoma of the thyroid: review of the literature with two new cases. (18302518)
2008
18
Preparation of Fe3O4@ZrO2 core-shell microspheres as affinity probes for selective enrichment and direct determination of phosphopeptides using matrix-assisted laser desorption ionization mass spectrometry. (17900103)
2007
19
Pathogenic mutations in Parkinson disease. (17385668)
2007
20
Imatinib mesylate in the treatment of systemic mastocytosis: a phase II trial. (16779792)
2006
21
Biology of hypoxia. (17294830)
2006
22
A routine liver transplantation in a patient with situs inversus: a case report and an overview of the literature. (16640519)
2006
23
Exercise-induced oxidative stress:myths, realities and physiological relevance. (16336008)
2005
24
Multifocal micronodular pneumocyte hyperplasia in a man with tuberous sclerosis. (15942095)
2005
25
Thromboxane synthase (TBXAS1) polymorphisms in African-American and Caucasian populations: evidence for selective pressure. (16134166)
2005
26
Unstable slipped capital femoral epiphysis: reduction by gradual distraction with external fixator. A case report. (16200018)
2005
27
Matrix metalloproteinase-2 contributes to cancer cell migration on collagen. (15665288)
2005
28
Enhanced radiosensitivity by inhibition of the anti-apoptotic gene clusterin using antisense oligodeoxynucleotide in a human bladder cancer model. (15809754)
2005
29
Leptin levels in the acute stage of ulcerative colitis. (15012781)
2004
30
Serum neuron-specific enolase in children with febrile seizures: time profile and prognostic implications. (12767459)
2003
31
Serum adiponectin levels in women with polycystic ovary syndrome. (12923129)
2003
32
Flow cytometric analysis of HLA-DR, IL-6 and IL-8 expression by conjunctival epithelial cells from patients with prolonged topical antiglaucoma treatments]. (14586218)
2003
33
Regulation of colony-stimulating factor-induced human myelopoiesis by transforming growth factor-beta isoforms. (12171249)
2002
34
Synergistic enhancement of cell-mediated immunity by interleukin-12 plus interleukin-2: basis for therapy of cutaneous T cell lymphoma. (11841558)
2002
35
Induction of Ca-independent PLA(2) and conservation of plasmalogen polyunsaturated fatty acids in diabetic heart. (10893319)
2000
36
The crystal structure of human eukaryotic release factor eRF1 -- mechanism of stop codon recognition and peptidyl-tRNA hydrolysis. (10676813)
2000
37
Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations. (9519718)
1998
38
Progressive familial intrahepatic cholestasis (PFIC): evidence for genetic heterogeneity by exclusion of linkage to chromosome 18q21-q22. (9272158)
1997
39
Cyclosporiasis: a new cause of diarrhea. (8911296)
1996
40
HMGI-C expression patterns in human tissues. Implications for the genesis of frequent mesenchymal tumors. (8780382)
1996
41
Hemicrania continua: remitting stage evolved from the chronic form. (7721578)
1995
42
Thrombin-Hirudin complex formation, thrombin-antithrombin III complex formation, and thrombin generation after intrinsic activation of plasma. (7855789)
1994
43
Pharmacologic manipulation of graft versus host induced splenomegaly. (1529801)
1992
44
Circulating hormone concentrations in hypothyroid rats with induced polycystic ovaries. (1924408)
1991
45
Syndrome of multiple organ failure]. (2263856)
1990
46
Kluver-Bucy syndrome. A case report. (2360478)
1990
47
Treatment of generalized pustular psoriasis with etretinate (Ro 10-9359) and methotrexate. (6707259)
1984
48
The surgical management of calcific tendinitis of the shoulder. An analysis of 100 consecutive cases. (5724542)
1968
49
An early account of an operation for anal fistula. (13935936)
1963

Variations for Linitis Plastica

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Expression for genes affiliated with Linitis Plastica

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Search GEO for disease gene expression data for Linitis Plastica.

Pathways for genes affiliated with Linitis Plastica

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GO Terms for genes affiliated with Linitis Plastica

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Biological processes related to Linitis Plastica according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix disassemblyGO:00226179.6CDH1, PRSS2

Sources for Linitis Plastica

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet