MCID: LNT001
MIFTS: 31

Linitis Plastica malady

Gastrointestinal diseases, Cancer diseases categories

Summaries for Linitis Plastica

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66Wikipedia, 34MalaCards
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Wikipedia:66 Linitis plastica, also known as Brinton\'s disease or leather bottle stomach, is a morphological variant... more...

MalaCards: Linitis Plastica, also known as leather-bottle stomach, is related to gastric linitis plastica and adenocarcinoma. An important gene associated with Linitis Plastica is PRSS2 (protease, serine, 2 (trypsin 2)). The compounds calcium and cysteine have been mentioned in the context of this disorder. Affiliated tissues include colon, breast and skin.

Aliases & Classifications for Linitis Plastica

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9Disease Ontology, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

linitis plastica 9 63
leather-bottle stomach 9


External Ids:

Disease Ontology9 DOID:4023
NCIt41 C3190
SNOMED-CT59 307594007, 37995004
MeSH36 D008039

Related Diseases for Linitis Plastica

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Linitis Plastica:



Diseases related to linitis plastica

Symptoms for Linitis Plastica

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Drugs & Therapeutics for Linitis Plastica

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Linitis Plastica

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Anatomical Context for Linitis Plastica

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Sources:
34MalaCards
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MalaCards organs/tissues related to Linitis Plastica:

34
Colon, Breast, Skin, Bone, Lymph node, Appendix

Animal Models for Linitis Plastica or affiliated genes

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Publications for Linitis Plastica

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53PubMed
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Articles related to Linitis Plastica:

(show top 50)    (show all 160)
idTitleAuthorsYear
1
Managing Gastric Linitis Plastica: Keep the scalpel sheathed. (23984032)
2013
2
Endoscopic ultrasonographic features of gastric linitis plastica in fifty-five Chinese patients. (24009205)
2013
3
Metastatic lobular breast cancer presenting as gastric linitis plastica. (21571246)
2011
4
Metastatic breast carcinoma simulating linitis plastica of the colon: report of a case. (21431489)
2011
5
Facing the challenge of managing linitis plastica--review of the literature. (20214236)
2009
6
Colorectal linitis plastica complicating chronic ulcerative colitis. (18798572)
2009
7
Metastatic gastric linitis plastica from bladder cancer mimicking a primary gastric carcinoma: a case report. (19885323)
2009
8
Linitis plastica of the rectum secondary to bladder carcinoma: a report of two cases and its MR features. (18796553)
2008
9
The number of metastatic lymph nodes is a significant risk factor for bone metastasis and poor outcome after surgery for linitis plastica-type gastric carcinoma. (18563480)
2008
10
Relatively small size linitis plastica of the stomach: multislice CT detection of tissue fibrosis. (17151892)
2007
11
TS-1 as first-line therapy for gastric linitis plastica: historical control study. (16702816)
2006
12
Cytologic diagnosis of gastric linitis plastica by endoscopic ultrasound guided fine-needle aspiration. (16511853)
2006
13
Linitis plastica due to gastric diverticulosis. (16140854)
2005
14
Gastric outlet obstruction secondary to linitis plastica of the stomach as shown on transabdominal sonography. (15292571)
2004
15
Gastrointestinal stromal tumour (GIST) masquerading as linitis plastica. (14717680)
2004
16
A new mutation of E-cadherin gene in familial gastric linitis plastica cancer with extra-digestive dissemination. (11434599)
2001
17
Linitis plastica presenting as malignant ascites. (11241451)
2001
18
Linitis plastica as the first indication of metastatic lobular carcinoma of the breast: case report and literature review. (10593250)
1999
19
Endoscopic ultrasonography in rectal linitis plastica. (9434221)
1997
20
Linitis plastica of the colon in ulcerative colitis. (9298379)
1997
21
Flow cytometry as a prognostic predictor in gastric linitis plastica. (8057648)
1994
22
Primary linitis plastica of the colon. (8224702)
1993
23
A case of linitis plastica of the rectum treated by pelvic exenteration after aggressive immunochemotherapy. (1498496)
1992
24
Kaposi's sarcoma presenting as linitis plastica. (1962631)
1991
25
Gastric linitis plastica metastatic to the uvea. (1751916)
1991
26
Linitis plastica of the alimentary tract and scrotum. (2153597)
1990
27
Primary linitis plastica of the descending colon: a case report. (2160554)
1990
28
Linitis plastica of the stomach and entire intestine. (3022171)
1986
29
Obstructive uropathy. An unusual presentation of primary linitis plastica of the colon. (2988885)
1985
30
Primary linitis plastica of the colon and rectum. Report of two cases. (6313308)
1983
31
Primary linitis plastica carcinoma of urinary bladder. (6312662)
1983
32
Primary linitis plastica of the rectum. (6295122)
1983
33
Primary signet ring cell adenocarcinoma of the bladder (linitis plastica of the bladder): report of a case and review of the literature. (6294348)
1982
34
Linitis plastica infiltrating the entire gut. (6285694)
1982
35
Metastatic carcinoma simulating linitis plastica of the colon. A case report. (220870)
1979
36
Linitis plastica in a 16-year-old. (171966)
1975
37
Primary linitis plastica carcinoma of the colon. (4370676)
1974
38
Gastric adenocarcinoma or linitis plastica in a dog. (4486933)
1973
39
Linitis plastica of the colon and rectum: report of two cases. (4337633)
1972
40
Linitis plastica carcinoma of the colon: report of a case. (4328825)
1971
41
Primary linitis plastica of the colon and rectum. (4319203)
1970
42
Slowly evolving widespread diffuse alimentary tract carcinoma (linitis plastica). (4300301)
1968
43
PRIMARY LINITIS PLASTICA CARCINOMA OF THE COLON. (14296754)
1965
44
LINITIS PLASTICA OR DIFFUSELY INFILTRATING TYPE OF CARCINOMA OF THE COLON. (14062258)
1963
45
Roentgenographic findings in an early case of linitis plastica. (14419028)
1960
46
Linitis plastica. (14406509)
1959
47
Linitis plastica carcinoma of the stomach with extensive metastases simulating a colonic lesion. (14906648)
1952
48
BENIGN HYPERTROPHY OF THE STOMACH AND LINITIS PLASTICA. (17865667)
1927
49
LINITIS PLASTICA. (17864459)
1921
50
VIII. Linitis Plastica (Cirrhosis of Stomach): With a Report of a Case Cured by Gastro-Jejunostomy. (17862763)
1911

Variations for Linitis Plastica

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Expression for genes affiliated with Linitis Plastica

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Linitis Plastica

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Pathways for genes affiliated with Linitis Plastica

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Compounds for genes affiliated with Linitis Plastica

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46Novoseek, 52PharmGKB, 25HMDB, 12DrugBank
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Compounds related to Linitis Plastica according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium46 52 25 1212.1CEACAM5, PRSS2
2cysteine468.8CEACAM5, PRSS2

GO Terms for genes affiliated with Linitis Plastica

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Products for genes affiliated with Linitis Plastica

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Linitis Plastica

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet