MCID: LPD007
MIFTS: 33

Lipoadenoma malady

Cancer diseases category
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Summaries for Lipoadenoma

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Disease Ontology:8 An adenoma that is composed of adipose tissue.

MalaCards based summary: Lipoadenoma is related to hyperparathyroidism and primary hyperparathyroidism. An important gene associated with Lipoadenoma is HMGA2 (high mobility group AT-hook 2), and among its related pathways is MicroRNAs in cancer. The compounds cisplatin and doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, thyroid and adrenal gland, and related mouse phenotypes are behavior/neurological and endocrine/exocrine gland.

Aliases & Classifications for Lipoadenoma

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Lipoadenoma, Aliases & Descriptions:

Name: Lipoadenoma 8 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:5398
SNOMED-CT57 22024005
NCIt39 C4159

Related Diseases for Lipoadenoma

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Graphical network of diseases related to Lipoadenoma:



Diseases related to lipoadenoma

Symptoms for Lipoadenoma

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Drugs & Therapeutics for Lipoadenoma

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Drug clinical trials:

Search ClinicalTrials for Lipoadenoma

Search NIH Clinical Center for Lipoadenoma

Genetic Tests for Lipoadenoma

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Anatomical Context for Lipoadenoma

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MalaCards organs/tissues related to Lipoadenoma:

32
Salivary gland, Thyroid, Adrenal gland

Animal Models for Lipoadenoma or affiliated genes

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MGI Mouse Phenotypes related to Lipoadenoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.5HMGA2, CRTC1, TP63
2MP:00053798.4HMGA2, CRTC1, TP63
3MP:00053898.2HMGA2, CRTC1, TP63

Publications for Lipoadenoma

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Articles related to Lipoadenoma:

(show all 42)
idTitleAuthorsYear
1
Oncocytic Lipoadenoma of the Salivary Gland: A Clinicopathologic Analysis of 7 Cases and Review of the Literature. (24737102)
2014
2
Virilizing lipoadenoma of the adrenal gland in a pre-pubertal girl: A rare case. (24744524)
2014
3
Oncocytic lipoadenoma of the parotid gland: Cytological findings and differential diagnosis on fine-needle aspiration. (24591268)
2014
4
Lipomatous salivary gland tumors: a series of 31 cases spanning their morphologic spectrum with emphasis on sialolipoma and oncocytic lipoadenoma. (23232852)
2013
5
Parathyroid lipoadenoma. (24224798)
2013
6
A rare case of double parathyroid lipoadenoma with hyperparathyroidism. (24157966)
2013
7
Ectopic atypical parathyroid lipoadenoma: a rare cause of severe primary hyperparathyroidism. (23263783)
2013
8
Oncocytic lipoadenoma of the parotid gland: a report of a new case and review of the literature. (23119120)
2012
9
Ectopic lipoadenoma of parathyroid. (23826002)
2012
10
Lipoadenoma of the parathyroid gland - a rare cause of hyperparathyroidism. (22227548)
2012
11
Importance of intraoperative parathyroid hormone measurement in the diagnosis of parathyroid lipoadenoma. (20091680)
2011
12
Images in endocrine pathology: lipoadenoma-like cystic epithelial lesion in the lateral neck. (21912964)
2011
13
Oncocytic lipoadenoma of the parotid gland: a case report with fine needle aspiration cytology findings. (20465541)
2010
14
Oncocytic lipoadenoma of the parotid gland with sebaceous differentiation in a 73-year-old male. (20828502)
2010
15
Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis. (19346081)
2010
16
Fine needle aspiration cytology of oncocytic lipoadenoma of the parotid gland: report of a rare case. (19697732)
2009
17
Tc-99m sestamibi parathyroid imaging in a rare case of parathyroid lipoadenoma. (19340525)
2009
18
Pathology quiz case 1. Oncocytic lipoadenoma of the parotid gland. (18427016)
2008
19
Inappropriate use of the term 'oncocytic lipoadenoma of the submandibular gland'. (18817942)
2008
20
Myxoid lipoadenoma of parathyroid gland: a case report and literature review. (16979523)
2006
21
Oncocytic lipoadenoma of the parotid gland with sebaceous differentiation. Study of its keratin profile. (17091251)
2006
22
Pathology quiz case 2. Parathyroid lipoadenoma. (17178956)
2006
23
Parathyroid lipoadenoma: case report and review of the literature. (17001900)
2006
24
Parotid lipoadenoma with sclerotic and polycystic changes. (12021932)
2002
25
Lipoadenoma: is it arising from thyroid or parathyroid? A diagnostic dilemma. (12499772)
2002
26
Oncocytic lipoadenoma of the parotid gland. (10809601)
2000
27
Oncocytic lipoadenoma of the submandibular gland. (9563794)
1998
28
Lipoadenoma of the parotid gland with probable striated duct differentiation. (9071732)
1997
29
Parathyroid lipoadenoma: case report and review of the literature. (8637760)
1996
30
CT of a parathyroid lipoadenoma. Case report. (8318300)
1993
31
Functioning lipoadenoma of the parathyroid: case report and literature review. (2664480)
1989
32
Functioning parathyroid lipoadenoma--report of four cases: clinicopathological and ultrasonographic features. (2659309)
1989
33
Severe vitamin D deficiency in a case of primary hyperparathyroidism caused by parathyroid lipoadenoma, effect of 25OHD3 treatment. (2615720)
1989
34
Functioning lipoadenoma of the parathyroid gland. (3071774)
1988
35
Parathyroid lipoadenoma: a rare cause of primary hyperparathyroidism. Case report. (3434106)
1987
36
Functioning parathyroid lipoadenoma. Report of a case diagnosed by intraoperative touch preparations. (3755027)
1986
37
A large functioning parathyroid lipoadenoma found in the posterior mediastinum. (7258157)
1981
38
Functioning lipoadenoma of a supernumerary parathyroid gland in the mediastinum. (7364585)
1980
39
Myxoid lipoadenoma of the parathyroid gland. (7220392)
1980
40
Lipoadenoma of the parathyroid gland. (637187)
1978
41
Functioning lipoadenoma of the parathyroid gland. (576197)
1977
42
Functioning lipoadenoma of the parathyroid gland. Report of a unique case. (13859106)
1962

Variations for Lipoadenoma

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Expression for genes affiliated with Lipoadenoma

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Expression patterns in normal tissues for genes affiliated with Lipoadenoma

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Pathways for genes affiliated with Lipoadenoma

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Pathways related to Lipoadenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3HMGA2, TP63

Compounds for genes affiliated with Lipoadenoma

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Compounds related to Lipoadenoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cisplatin44 50 61 1112.3HMGA2, TP63
2doxorubicin44 50 1111.2HMGA2, TP63
3paraffin449.0HMGA2, TP63

GO Terms for genes affiliated with Lipoadenoma

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Cellular components related to Lipoadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056548.5HMGA2, MAML2, TP63
2nucleusGO:0056348.0HMGA2, CRTC1, MAML2, TP63

Biological processes related to Lipoadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription, DNA-templatedGO:0458939.3HMGA2, TP63
2Notch signaling pathwayGO:0072199.3TP63, MAML2
3negative regulation of transcription, DNA-templatedGO:0458929.2HMGA2, TP63
4protein homotetramerizationGO:0512899.1CRTC1, TP63
5negative regulation of apoptotic processGO:0430669.0HMGA2, TP63
6positive regulation of transcription from RNA polymerase II promoterGO:0459448.1HMGA2, CRTC1, MAML2, TP63

Molecular functions related to Lipoadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionGO:0010779.3HMGA2, TP63

Products for genes affiliated with Lipoadenoma

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  • Antibodies
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Sources for Lipoadenoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet