MCID: LPD007
MIFTS: 32

Lipoadenoma malady

Cancer diseases category

Summaries for Lipoadenoma

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Sources:
9Disease Ontology, 34MalaCards
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Disease Ontology:9 An adenoma that is composed of adipose tissue.

MalaCards: Lipoadenoma is related to hyperparathyroidism and primary hyperparathyroidism. An important gene associated with Lipoadenoma is HMGA2 (high mobility group AT-hook 2), and among its related pathways is MicroRNAs in cancer. The compounds cisplatin and doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include thyroid and salivary gland, and related mouse phenotypes are behavior/neurological and endocrine/exocrine gland.

Aliases & Classifications for Lipoadenoma

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 41NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

lipoadenoma 9 11 63


External Ids:

Disease Ontology9 DOID:5398
SNOMED-CT59 22024005
NCIt41 C4159

Related Diseases for Lipoadenoma

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of diseases related to Lipoadenoma:



Diseases related to lipoadenoma

Symptoms for Lipoadenoma

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Drugs & Therapeutics for Lipoadenoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Lipoadenoma

Drug clinical trials:

Search ClinicalTrials for Lipoadenoma

Search NIH Clinical Center for Lipoadenoma

Search CenterWatch for Lipoadenoma

Genetic Tests for Lipoadenoma

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Anatomical Context for Lipoadenoma

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Sources:
34MalaCards
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MalaCards organs/tissues related to Lipoadenoma:

34
Thyroid, Salivary gland

Animal Models for Lipoadenoma or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Lipoadenoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.5HMGA2, CRTC1, TP63
2MP:00053798.4HMGA2, CRTC1, TP63
3MP:00053898.2HMGA2, CRTC1, TP63

Publications for Lipoadenoma

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Sources:
53PubMed
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Articles related to Lipoadenoma:

(show all 39)
idTitleAuthorsYear
1
Lipomatous salivary gland tumors: a series of 31 cases spanning their morphologic spectrum with emphasis on sialolipoma and oncocytic lipoadenoma. (23232852)
2013
2
Parathyroid lipoadenoma. (24224798)
2013
3
A rare case of double parathyroid lipoadenoma with hyperparathyroidism. (24157966)
2013
4
Ectopic atypical parathyroid lipoadenoma: a rare cause of severe primary hyperparathyroidism. (23263783)
2013
5
Oncocytic lipoadenoma of the parotid gland: a report of a new case and review of the literature. (23119120)
2012
6
Ectopic lipoadenoma of parathyroid. (23826002)
2012
7
Lipoadenoma of the parathyroid gland - a rare cause of hyperparathyroidism. (22227548)
2012
8
Importance of intraoperative parathyroid hormone measurement in the diagnosis of parathyroid lipoadenoma. (20091680)
2011
9
Images in endocrine pathology: lipoadenoma-like cystic epithelial lesion in the lateral neck. (21912964)
2011
10
Oncocytic lipoadenoma of the parotid gland: a case report with fine needle aspiration cytology findings. (20465541)
2010
11
Oncocytic lipoadenoma of the parotid gland with sebaceous differentiation in a 73-year-old male. (20828502)
2010
12
Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis. (19346081)
2010
13
Fine needle aspiration cytology of oncocytic lipoadenoma of the parotid gland: report of a rare case. (19697732)
2009
14
Tc-99m sestamibi parathyroid imaging in a rare case of parathyroid lipoadenoma. (19340525)
2009
15
Pathology quiz case 1. Oncocytic lipoadenoma of the parotid gland. (18427016)
2008
16
Inappropriate use of the term 'oncocytic lipoadenoma of the submandibular gland'. (18817942)
2008
17
Myxoid lipoadenoma of parathyroid gland: a case report and literature review. (16979523)
2006
18
Oncocytic lipoadenoma of the parotid gland with sebaceous differentiation. Study of its keratin profile. (17091251)
2006
19
Pathology quiz case 2. Parathyroid lipoadenoma. (17178956)
2006
20
Parathyroid lipoadenoma: case report and review of the literature. (17001900)
2006
21
Parotid lipoadenoma with sclerotic and polycystic changes. (12021932)
2002
22
Lipoadenoma: is it arising from thyroid or parathyroid? A diagnostic dilemma. (12499772)
2002
23
Oncocytic lipoadenoma of the parotid gland. (10809601)
2000
24
Oncocytic lipoadenoma of the submandibular gland. (9563794)
1998
25
Lipoadenoma of the parotid gland with probable striated duct differentiation. (9071732)
1997
26
Parathyroid lipoadenoma: case report and review of the literature. (8637760)
1996
27
CT of a parathyroid lipoadenoma. Case report. (8318300)
1993
28
Functioning lipoadenoma of the parathyroid: case report and literature review. (2664480)
1989
29
Functioning parathyroid lipoadenoma--report of four cases: clinicopathological and ultrasonographic features. (2659309)
1989
30
Severe vitamin D deficiency in a case of primary hyperparathyroidism caused by parathyroid lipoadenoma, effect of 25OHD3 treatment. (2615720)
1989
31
Functioning lipoadenoma of the parathyroid gland. (3071774)
1988
32
Parathyroid lipoadenoma: a rare cause of primary hyperparathyroidism. Case report. (3434106)
1987
33
Functioning parathyroid lipoadenoma. Report of a case diagnosed by intraoperative touch preparations. (3755027)
1986
34
A large functioning parathyroid lipoadenoma found in the posterior mediastinum. (7258157)
1981
35
Functioning lipoadenoma of a supernumerary parathyroid gland in the mediastinum. (7364585)
1980
36
Myxoid lipoadenoma of the parathyroid gland. (7220392)
1980
37
Lipoadenoma of the parathyroid gland. (637187)
1978
38
Functioning lipoadenoma of the parathyroid gland. (576197)
1977
39
Functioning lipoadenoma of the parathyroid gland. Report of a unique case. (13859106)
1962

Variations for Lipoadenoma

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Expression for genes affiliated with Lipoadenoma

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lipoadenoma

Search GEO for disease gene expression data for Lipoadenoma.

Pathways for genes affiliated with Lipoadenoma

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Sources:
51PathCards, 31KEGG
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Pathways related to Lipoadenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3HMGA2, TP63

Compounds for genes affiliated with Lipoadenoma

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Sources:
46Novoseek, 52PharmGKB, 62Tocris Bioscience, 12DrugBank
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Compounds related to Lipoadenoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cisplatin46 52 62 1212.3HMGA2, TP63
2doxorubicin46 52 1211.2HMGA2, TP63
3paraffin469.0HMGA2, TP63

GO Terms for genes affiliated with Lipoadenoma

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Sources:
17Gene Ontology
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Cellular components related to Lipoadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056548.5HMGA2, MAML2, TP63
2nucleusGO:0056348.0HMGA2, CRTC1, MAML2, TP63

Biological processes related to Lipoadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription, DNA-templatedGO:0458939.3HMGA2, TP63
2Notch signaling pathwayGO:0072199.3TP63, MAML2
3negative regulation of transcription, DNA-templatedGO:0458929.2HMGA2, TP63
4protein homotetramerizationGO:0512899.1CRTC1, TP63
5negative regulation of apoptotic processGO:0430669.0HMGA2, TP63
6positive regulation of transcription from RNA polymerase II promoterGO:0459448.1HMGA2, CRTC1, MAML2, TP63

Molecular functions related to Lipoadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionGO:0010779.3HMGA2, TP63

Products for genes affiliated with Lipoadenoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Lipoadenoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet