Aliases & Classifications for Lipoblastoma

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Sources:
46NIH Rare Diseases, 52Orphanet, 66UMLS, 67UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Lipoblastoma:

Name: Lipoblastoma 46 52 66

Characteristics:

Orphanet epidemiological data:

52
lipoblastoma:
Inheritance: Not applicable; Age of onset: Childhood

Classifications:



External Ids:

Orphanet52 ORPHA247762
UMLS via Orphanet67 C1260965

Summaries for Lipoblastoma

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Wikipedia:69 Lipoblastoma is a type of subcutaneous benign fatty tumor. more...

MalaCards based summary: Lipoblastoma is related to deafness, autosomal recessive 91 and hodgkin's lymphoma, lymphocytic-histiocytic predominance. An important gene associated with Lipoblastoma is HAS2 (Hyaluronan Synthase 2), and among its related pathways are Platelet Aggregation Inhibitor Pathway, Pharmacodynamics and Endothelins. Affiliated tissues include breast, bone and adipocyte, and related mouse phenotypes are limbs/digits/tail and liver/biliary system.

Related Diseases for Lipoblastoma

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Diseases related to Lipoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1deafness, autosomal recessive 9110.5COL1A2, COL3A1
2hodgkin's lymphoma, lymphocytic-histiocytic predominance10.3COL1A2, COL3A1
3mediastinitis10.3
4strongyloidiasis10.3COL1A2, COL3A1
5cervicitis10.3
6chromosome 7p duplication10.2CDK4, MDM2
7epidural spinal canal angiolipoma10.2CDK4, MDM2
8osteogenesis imperfecta10.2CDK4, MDM2
9familial long qt syndrome10.2CDK4, MDM2
10skin lipoma10.2CDK4, MDM2
11liposarcoma10.2
12conjunctivitis10.2CDK4, MDM2
13conventional central osteosarcoma10.2CDK4, MDM2
14pediatric osteosarcoma10.2CDK4, MDM2
15localized chondrosarcoma10.2CDK4, MDM2
16spindle cell liposarcoma10.2CDK4, MDM2
17pleuropulmonary blastoma type 210.2CDK4, MDM2
18fibrosarcoma10.2CDK4, MDM2
19kidney lipoma10.2CDK4, MDM2
20lipoma10.2
21breast capillary hemangioma10.2CDK4, MDM2
22cholelithiasis10.2CDK4, MDM2
23vulvar liposarcoma10.2CDK4, MDM2
24lumbosacral lipoma10.2CDK4, MDM2
25toxascariasis10.2CDK4, MDM2
26bone osteosarcoma10.1CDK4, MDM2
27emerinopathy10.1CDK4, MDM2
28vulvar sebaceous carcinoma10.1CDK4, MDM2
29small cell osteogenic sarcoma10.1CDK4, MDM2
30epidural neoplasm10.1CDK4, MDM2
31localized osteosarcoma10.1CDK4, MDM2
32myxoid liposarcoma10.1
33bilateral retinoblastoma10.1CDK4, MDM2
34placental choriocarcinoma10.0CDK4, MDM2
35pharynx cancer10.0CDK4, MDM2
36rhabdomyosarcoma 2, alveolar10.0CDK4, MDM2
37hemangioma9.9
38atypical lipomatous tumor9.9
39vitamin d-dependent rickets, type i9.9CDK4, MDM2
40cellular myxoid liposarcoma9.9CDK4, MDM2, PLAG1
41ascending colon cancer9.9CDK4, MDM2
42periodontal disease9.8CDK4, MDM2
43clear cell sarcoma9.8CDK4, MDM2
44glomuvenous malformations9.8
45alopecia9.8
46hepatitis9.8
47fibroma9.8
48inguinal hernia9.8
49diaphragmatic eventration9.8
50ossifying fibroma9.8

Graphical network of the top 20 diseases related to Lipoblastoma:



Diseases related to lipoblastoma

Symptoms for Lipoblastoma

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Drugs & Therapeutics for Lipoblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Lipoblastoma

Genetic Tests for Lipoblastoma

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Anatomical Context for Lipoblastoma

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MalaCards organs/tissues related to Lipoblastoma:

34
Breast, Bone, Adipocyte, Testes, Kidney, Skin

Animal Models for Lipoblastoma or affiliated genes

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MGI Mouse Phenotypes related to Lipoblastoma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.2COL1A2, HAS2, LEP, LEPR, MDM2
2MP:00053708.1CDK4, COL3A1, LEP, LEPR, MDM2
3MP:00053817.8CDK4, COL3A1, LEP, LEPR, MDM2
4MP:00107717.7CDK4, COL1A2, COL3A1, LEP, LEPR, MDM2
5MP:00053807.4CDK4, HAS2, LEP, LEPR, MDM2, PLAG1
6MP:00053697.3CDK4, COL1A2, COL3A1, HAS2, LEP, LEPR
7MP:00053857.0CDK4, COL1A2, COL3A1, HAS2, LEP, LEPR
8MP:00053766.7CDK4, COL1A2, COL3A1, HAS2, LEP, LEPR
9MP:00053786.4CDK4, COL1A2, COL3A1, HAS2, LEP, LEPR

Publications for Lipoblastoma

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Articles related to Lipoblastoma:

(show top 50)    (show all 247)
idTitleAuthorsYear
1
Immunohistochemical expression of p16 in lipoblastomas. (26514741)
2016
2
Undifferentiated myxoid lipoblastoma with PLAG1-HAS2 fusion in an infant; morphologically mimicking primitive myxoid mesenchymal tumor of infancy (PMMTI)-diagnostic importance of cytogenetic and molecular testing and literature review. (26701195)
2016
3
Lipoblastoma presenting as a rapidly growing paravertebral mass and masquerading as myxoid liposarcoma on fine needle aspiration cytology. (26919610)
2016
4
Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma. (24700772)
2014
5
Giant gluteal lipoblastoma associated with hepatic haemangioma and bilateral nephromegaly. (24849628)
2014
6
A giant omental Lipoblastoma in a four-year-old boy. (24955971)
2014
7
Perineal lipoblastoma: a case report and review of literature. (25031762)
2014
8
Desmin-positivity in spindle cells: under-recognized immunophenotype of lipoblastoma. (23865573)
2013
9
Diagnostic utility of molecular and cytogenetic analysis in lipoblastoma: a study of two cases and review of the literature. (24433523)
2013
10
Intrascrotal lipoblastoma in a ten year old: case report and review of literature. (23772297)
2013
11
A rare case of inguinolabial lipoblastoma in a 13-month-old female. (23103129)
2013
12
Multifocal lipoblastoma of the face. (23172486)
2012
13
Retroperitoneal lipoblastoma: a discussion of current management. (23084233)
2012
14
Lipoblastoma mimicking myxoid liposarcoma: a clinical report and literature review. (21212605)
2011
15
Acute respiratory distress caused by a giant mediastinal lipoblastoma in a 16-month-old boy. (22115267)
2011
16
Lipoblastoma-like tumour of the lip in an adult woman. (20814641)
2010
17
Lipoblastoma--an unfamiliar but important diagnosis. A case series and literature review. (19774822)
2009
18
Mesenteric lipoblastoma presenting as a segmental volvulus. (19231517)
2009
19
Giant mesenteric lipoblastoma in a 4-year-old child. (19361656)
2009
20
A collection of rare anomalies: multiple digital glomuvenous malformations, epidermal naevus, temporal alopecia, heterochromia and abdominal lipoblastoma. (20055849)
2009
21
A case of maturing perineal lipoblastoma in an infant. (19494545)
2009
22
Lipoblastoma in children: an analysis of 5 cases. (19051470)
2008
23
Lipoblastoma: appreciation of an expanded spectrum of disease through cytogenetic analysis. (18788858)
2008
24
Contemporary management of lipoblastoma. (18639685)
2008
25
Fine-needle aspiration cytology of a lipoblastoma: a case report. (18528880)
2008
26
Unusual breast enlargement in an infant: a case of breast lipoblastoma. (17051354)
2007
27
Congenital lipoblastoma in a neonate calf: first report in veterinary literature. (17355429)
2007
28
Benign intrascrotal lipoblastoma in a child. (17826513)
2007
29
Lipoblastoma--a rare paediatric foot tumour. (17715735)
2007
30
Intrapelvic lipoblastoma with massive spinal canal invasion. (17143644)
2007
31
Surgical management of lipoblastoma. (16769336)
2006
32
Lipoblastoma in a four-year-old African child. (16338874)
2005
33
Infantile cervical lipoblastoma: a case report and review of the literature. (15015175)
2004
34
Axillary lipoblastoma--tumor recurrence in the right atrium. (12891504)
2003
35
Fine needle aspiration diagnosis of lipoblastoma of the parotid region. A case report. (11917592)
2002
36
Lipoblastoma. (11381423)
2001
37
Evidence by spectral karyotyping that 8q11.2 is nonrandomly involved in lipoblastoma. (11272891)
2000
38
Lipoblastoma of the neck. (10878874)
2000
39
Lipoblastoma presenting as a mesenteric mass in an infant. (9856685)
1998
40
Lipoblastoma: a case with t(7;8)(q31;q13). (9530333)
1998
41
Congenital orbital lipoblastoma: a pathologic and radiologic study. (9168428)
1997
42
Lipoblastoma in the parotid gland of an infant. (9419158)
1997
43
Lipoblastoma of the foot. (8741069)
1996
44
Two rapidly growing fatty tumors of the upper limb in children: lipoblastoma and infiltrating lipoma. (7722258)
1995
45
Shoulder lipoblastoma: magnetic resonance imaging characteristics. (8504336)
1993
46
Case report 675: Lipoblastoma of knee. (1853230)
1991
47
Congenital palpebral lipoblastoma. First report of a case. (2393069)
1990
48
Parotid lipoblastoma in an infant. (3429147)
1987
49
Benign lipoblastoma in the mandible. (6841120)
1983
50
Benign lipoblastoma in the neck causing respiratory insufficiency. (6865630)
1983

Variations for Lipoblastoma

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Expression for genes affiliated with Lipoblastoma

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Search GEO for disease gene expression data for Lipoblastoma.

Pathways for genes affiliated with Lipoblastoma

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GO Terms for genes affiliated with Lipoblastoma

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Biological processes related to Lipoblastoma according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1bone growthGO:009886810.0LEP, LEPR
2energy reserve metabolic processGO:000611210.0LEP, LEPR
3sexual reproductionGO:00199539.9LEP, LEPR
4leptin-mediated signaling pathwayGO:00332109.9LEP, LEPR
5regulation of bone remodelingGO:00468509.9LEP, LEPR
6collagen fibril organizationGO:00301999.8COL1A2, COL3A1
7cellular response to amino acid stimulusGO:00712309.8COL1A2, COL3A1
8negative regulation of cell cycle arrestGO:00711579.7CDK4, MDM2
9positive regulation of cell cycleGO:00457879.7CDK4, MDM2
10negative regulation of autophagyGO:00105079.7LEP, LEPR
11T cell differentiationGO:00302179.6LEP, LEPR
12phagocytosisGO:00069099.5LEP, LEPR
13blood vessel developmentGO:00015689.5COL1A2, COL3A1, MDM2
14positive regulation of cell proliferationGO:00082848.3CDK4, HAS2, LEP, MDM2

Molecular functions related to Lipoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet-derived growth factor bindingGO:00484079.8COL1A2, COL3A1
2SMAD bindingGO:00463329.8COL1A2, COL3A1

Sources for Lipoblastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet