MCID: LPB001
MIFTS: 26

Lipoblastoma malady

Cancer diseases category

Summaries for Lipoblastoma

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Sources:
63Wikipedia, 32MalaCards
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Wikipedia:63 Lipoblastoma is a type of subcutaneous benign fatty tumor. more...

MalaCards: Lipoblastoma is related to mediastinitis and cervicitis. An important gene associated with Lipoblastoma is COL1A2 (collagen, type I, alpha 2), and among its related pathways are Adipocytokine signaling pathway and AMPK signaling. The compounds xbai and lep (116-130) (mouse) have been mentioned in the context of this disorder. Related mouse phenotypes are limbs/digits/tail and cardiovascular system.

Aliases & Classifications for Lipoblastoma

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Sources:
42NIH Rare Diseases, 48Orphanet, 60UMLS, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Characteristics (Orphanet epidemiological data):

48
lipoblastoma:
Inheritance: Sporadic; Age of onset: Childhood


Aliases & Descriptions:

lipoblastoma 42 48 60


External Ids:

SNOMED-CT via Orphanet57 400102008
UMLS via Orphanet61 C1260965

Related Diseases for Lipoblastoma

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Lipoblastoma:



Diseases related to lipoblastoma

Clinical Features for Lipoblastoma

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Drugs & Therapeutics for Lipoblastoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Lipoblastoma

Drug clinical trials:

Search ClinicalTrials for Lipoblastoma

Search NIH Clinical Center for Lipoblastoma

Search CenterWatch for Lipoblastoma

Genetic Tests for Lipoblastoma

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Anatomical Context for Lipoblastoma

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Animal Models for Lipoblastoma or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Lipoblastoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.4LEPR, LEP, HAS2, COL1A2
2MP:00053858.4LEPR, LEP, HAS2, COL1A2
3MP:00053698.3COL1A2, HAS2, LEP, LEPR
4MP:00053908.1COL1A2, HAS2, LEP, LEPR
5MP:00053787.5COL1A2, HAS2, LEP, LEPR, PLAG1

Publications for Lipoblastoma

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Genetic Variations for Lipoblastoma

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Expression for genes affiliated with Lipoblastoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lipoblastoma

Search GEO for disease gene expression data for Lipoblastoma.

Pathways for genes affiliated with Lipoblastoma

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Sources:
29KEGG, 37NCBI BioSystems Database, 12EMD Millipore
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Pathways related to Lipoblastoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3LEPR, LEP
29.3LEPR, LEP
3
Development Leptin signaling via PI3K-dependent pathway
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9.3LEP, LEPR
49.3LEPR, LEP
5
Development Leptin signaling via JAK/STAT and MAPK cascades
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9.3LEPR, LEP

Compounds for genes affiliated with Lipoblastoma

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Sources:
44Novoseek, 59Tocris Bioscience, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Lipoblastoma according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1xbai449.7LEPR, COL1A2
2lep (116-130) (mouse)599.6LEPR, LEP
3nash449.6LEPR, LEP
4olanzapine49 44 28 11 2413.5LEP, LEPR
5triacylglycerol449.5LEPR, LEP
6triiodothyronine449.5LEPR, LEP
7androstenedione44 2410.4LEP, LEPR
8corticosterone44 59 2411.3LEPR, LEP
9cocaine44 1110.3LEPR, LEP
10steroid448.9LEPR, LEP, HAS2
11dexamethasone44 49 28 1111.7HAS2, LEP, LEPR
12phosphatidylinositol448.6LEPR, LEP, COL1A2

GO Terms for genes affiliated with Lipoblastoma

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Sources:
16Gene Ontology
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Biological processes related to Lipoblastoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1energy reserve metabolic processGO:0061129.3LEPR, LEP
2regulation of blood pressureGO:0082179.3LEP, COL1A2
3cholesterol metabolic processGO:0082039.0LEPR, LEP

Products for genes affiliated with Lipoblastoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Lipoblastoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet