MCID: LPB001
MIFTS: 35

Lipoblastoma malady

Rare diseases, Cancer diseases categories

Aliases & Classifications for Lipoblastoma

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Sources:
41NIH Rare Diseases, 47Orphanet, 60UMLS, 61UMLS via Orphanet
See all sources

Lipoblastoma, Aliases & Descriptions:

Name: Lipoblastoma 41 47 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Orphanet: 47 
Rare tumors


Characteristics (Orphanet epidemiological data):

47
lipoblastoma:
Inheritance: Not applicable; Age of onset: Childhood


External Ids:

Orphanet47 247762
UMLS via Orphanet61 C1260965

Summaries for Lipoblastoma

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Wikipedia:63 Lipoblastoma is a type of subcutaneous benign fatty tumor. more...

MalaCards based summary: Lipoblastoma is related to mediastinitis and cervicitis. An important gene associated with Lipoblastoma is COL1A2 (collagen, type I, alpha 2), and among its related pathways are Adipocytokine signaling pathway and Prolactin signaling pathway. The compounds ribonucleic acid and xbai have been mentioned in the context of this disorder. Affiliated tissues include bone, adipocyte and breast, and related mouse phenotypes are vision/eye and limbs/digits/tail.

Related Diseases for Lipoblastoma

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Graphical network of the top 20 diseases related to Lipoblastoma:



Diseases related to lipoblastoma

Symptoms for Lipoblastoma

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Drugs & Therapeutics for Lipoblastoma

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Drug clinical trials:

Search ClinicalTrials for Lipoblastoma

Search NIH Clinical Center for Lipoblastoma

Genetic Tests for Lipoblastoma

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Anatomical Context for Lipoblastoma

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MalaCards organs/tissues related to Lipoblastoma:

31
Bone, Adipocyte, Breast, Kidney, Skin, Testes

Animal Models for Lipoblastoma or affiliated genes

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MGI Mouse Phenotypes related to Lipoblastoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.5PLAG1, LEP, LEPR
2MP:00053718.5COL1A2, LEP, LEPR, HAS2
3MP:00053698.4COL1A2, LEP, LEPR, HAS2
4MP:00053908.4HAS2, LEPR, LEP, COL1A2
5MP:00053858.3COL1A2, LEP, LEPR, HAS2
6MP:00053868.1HAS2, LEPR, LEP, COL1A2
7MP:00053787.6HAS2, LEPR, LEP, PLAG1, COL1A2

Publications for Lipoblastoma

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Articles related to Lipoblastoma:

(show top 50)    (show all 227)
idTitleAuthorsYear
1
Lipoblastoma mimicking inguinal hernia. (25628996)
2015
2
Lipoblastoma and lipoblastomatosis of the lower leg. (25302126)
2014
3
An isolated digital lipoblastoma. (23789709)
2014
4
Recurrent lipoblastoma of upper extremity in a 9-year-old boy. (24713710)
2014
5
Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma. (24700772)
2014
6
Giant gluteal lipoblastoma associated with hepatic haemangioma and bilateral nephromegaly. (24849628)
2014
7
Desmin-positivity in spindle cells: under-recognized immunophenotype of lipoblastoma. (23865573)
2013
8
Diagnostic utility of molecular and cytogenetic analysis in lipoblastoma: a study of two cases and review of the literature. (24433523)
2013
9
A novel PLAG1-RAD51L1 gene fusion resulting from a t(8;14)(q12;q24) in a case of lipoblastoma. (23890983)
2013
10
Giant omental lipoblastoma and CD56 expression. (23519855)
2013
11
Intrascrotal lipoblastoma in a ten year old: case report and review of literature. (23772297)
2013
12
Multifocal lipoblastoma of the face. (23172486)
2012
13
A giant mesenteric lipoblastoma in an 18-month old infant: a case report and review of the literature. (22248900)
2011
14
Intrathoracic lipoblastoma in a 15-month-old infant. (22355506)
2011
15
A case of lipoblastoma with seven copies of chromosome 8. (19264235)
2009
16
Lipoblastoma--an unfamiliar but important diagnosis. A case series and literature review. (19774822)
2009
17
Mesenteric lipoblastoma presenting as a segmental volvulus. (19231517)
2009
18
Lipoblastoma on the posterior side of the neck. (19817275)
2009
19
Lipoblastoma in adolescents and young adults: report of six cases with FISH analysis. (18269579)
2008
20
Lipoblastoma in children: an analysis of 5 cases. (19051470)
2008
21
Lipoblastoma: appreciation of an expanded spectrum of disease through cytogenetic analysis. (18788858)
2008
22
Unusual breast enlargement in an infant: a case of breast lipoblastoma. (17051354)
2007
23
Congenital lipoblastoma in a neonate calf: first report in veterinary literature. (17355429)
2007
24
Benign intrascrotal lipoblastoma in a child. (17826513)
2007
25
Omental lipoblastoma. (18693617)
2007
26
Lipoblastoma and infantile lipoma. (17146210)
2006
27
A thoracic wall lipoblastoma in a 3-month-old infant: A case report and review of the literature. (17006266)
2006
28
Lipoblastoma in a four-year-old African child. (16338874)
2005
29
Lipoblastoma of the neck mimicking cystic hygroma. (15746874)
2005
30
Lipoblastoma in an 11-month-old infant. (15322609)
2004
31
Intrascrotal lipoblastoma with a complex karyotype: a case report and review of the literature. (15214818)
2004
32
Axillary lipoblastoma--tumor recurrence in the right atrium. (12891504)
2003
33
Primary cardiac lipoblastoma. (11370265)
2001
34
PLAG1 fusion oncogenes in lipoblastoma. (10987300)
2000
35
Lipoblastoma with aberration in the long arm of chromosome 8. (10982693)
2000
36
A further case of chromosome 8q rearrangement in lipoblastoma. (11037871)
2000
37
Ruptured giant intrathoracic lipoblastoma in a 4-month-old infant: CT and MR findings. (10663508)
2000
38
Evidence by spectral karyotyping that 8q11.2 is nonrandomly involved in lipoblastoma. (11272891)
2000
39
"Lipoblastoma-like" lipoatrophy induced by human insulin: morphological evidence for local dedifferentiation of adipocytes? (10952472)
2000
40
Lipoblastoma: MRI appearances of a rare paediatric soft tissue tumour. (10398794)
1999
41
Lipoblastoma presenting as a mesenteric mass in an infant. (9856685)
1998
42
Chromosomal aberration in lipoblastoma: a case with 46,XX,ins(8;6)(q11.2;q13q27). (9169035)
1997
43
Lipoblastoma of the foot. (8741069)
1996
44
An unusual intrathoracic tumor: giant lipoblastoma. (7756235)
1995
45
New discriminative chromosomal marker in adipose tissue tumors. The chromosome 8q11-q13 region in lipoblastoma. (7828158)
1994
46
Potential diagnostic implications of breakpoints in the long arm of chromosome 8 in lipoblastoma. (8076349)
1994
47
Lipoblastoma and lipoblastomatosis--a report of six cases. (3413688)
1988
48
Benign lipoblastoma in the mandible. (6841120)
1983
49
Benign lipoblastoma in the neck causing respiratory insufficiency. (6865630)
1983
50
Benign lipoblastoma and myxoid liposarcoma: a comparative light- and electron-microscopic study. (7377463)
1980

Variations for Lipoblastoma

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Expression for genes affiliated with Lipoblastoma

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Search GEO for disease gene expression data for Lipoblastoma.

Pathways for genes affiliated with Lipoblastoma

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Pathways related to Lipoblastoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3LEP, LEPR
2
Show member pathways
Prolactin Signaling Pathway36
Development Prolactin receptor signaling58
Leptin signaling pathway36
9.3LEP, LEPR
3
Show member pathways
Type III interferon signaling36
9.3LEP, LEPR
49.3LEPR, LEP
59.3LEP, LEPR
6
Show member pathways
9.3LEP, LEPR
79.3LEP, LEPR
8
Show member pathways
9.3LEP, LEPR

Compounds for genes affiliated with Lipoblastoma

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Compounds related to Lipoblastoma according to GeneCards Suite gene sharing:

(show all 23)
idCompoundScoreTop Affiliating Genes
1ribonucleic acid4310.0COL1A2
2xbai439.8COL1A2, LEPR
3simvastatin43 49 59 28 24 1214.7COL1A2, LEPR
4lep (116-130) (mouse)599.7LEP, LEPR
5nash439.7LEP, LEPR
6olanzapine43 49 28 24 1213.7LEPR, LEP
7triacylglycerol439.7LEP, LEPR
8triiodothyronine439.6LEPR, LEP
9androstenedione43 2410.6LEP, LEPR
10corticosterone43 59 2411.6LEPR, LEP
11cocaine43 1210.6LEPR, LEP
12thyroxine43 2410.5LEPR, LEP
13hyaluronic acid43 2410.4LEP, HAS2
14prostacyclin439.4LEP, HAS2
15acth439.3LEPR, LEP
16gnrh439.2LEP, LEPR
17phosphatidylinositol439.1COL1A2, LEP, LEPR
18steroid439.1LEP, LEPR, HAS2
19estrogen439.1COL1A2, LEP, LEPR
20dexamethasone43 49 28 1212.1LEP, LEPR, HAS2
21cysteine439.1LEPR, LEP, COL1A2
22glucose439.0LEP, LEPR, HAS2
23lipid438.5LEP, LEPR, HAS2

GO Terms for genes affiliated with Lipoblastoma

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Biological processes related to Lipoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1energy reserve metabolic processGO:00061129.3LEP, LEPR
2regulation of blood pressureGO:00082179.3COL1A2, LEP
3cholesterol metabolic processGO:00082039.0LEP, LEPR

Products for genes affiliated with Lipoblastoma

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Sources for Lipoblastoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet