MCID: LPB001
MIFTS: 41

Lipoblastoma malady

Rare diseases, Cancer diseases categories
Download this MalaCard

Summaries for Lipoblastoma

About this section


Fully expand this MalaCard
Wikipedia:65 Lipoblastoma is a type of subcutaneous benign fatty tumor. more...

MalaCards based summary: Lipoblastoma is related to mediastinitis and cervicitis. An important gene associated with Lipoblastoma is COL1A2 (collagen, type I, alpha 2), and among its related pathways are Adipocytokine signaling pathway and Prolactin signaling pathway. The compounds ribonucleic acid and xbai have been mentioned in the context of this disorder. Affiliated tissues include bone, adipocyte and breast, and related mouse phenotypes are vision/eye and limbs/digits/tail.

Aliases & Classifications for Lipoblastoma

About this section
Sources:
42NIH Rare Diseases, 48Orphanet, 62UMLS, 63UMLS via Orphanet
See all sources

Lipoblastoma, Aliases & Descriptions:

Name: Lipoblastoma 42 48 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Orphanet: 48 
Rare tumors


Characteristics (Orphanet epidemiological data):

48
lipoblastoma:
Inheritance: Sporadic; Age of onset: Childhood


External Ids:

UMLS via Orphanet63 C1260965

Related Diseases for Lipoblastoma

About this section

Graphical network of the top 20 diseases related to Lipoblastoma:



Diseases related to lipoblastoma

Symptoms for Lipoblastoma

About this section

Drugs & Therapeutics for Lipoblastoma

About this section

Drug clinical trials:

Search ClinicalTrials for Lipoblastoma

Search NIH Clinical Center for Lipoblastoma

Genetic Tests for Lipoblastoma

About this section

Anatomical Context for Lipoblastoma

About this section

MalaCards organs/tissues related to Lipoblastoma:

32
Bone, Adipocyte, Breast, Kidney, Skin, Testes

Animal Models for Lipoblastoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Lipoblastoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.5PLAG1, LEP, LEPR
2MP:00053718.5COL1A2, LEP, LEPR, HAS2
3MP:00053698.4COL1A2, LEP, LEPR, HAS2
4MP:00053908.4HAS2, LEPR, LEP, COL1A2
5MP:00053858.3COL1A2, LEP, LEPR, HAS2
6MP:00053868.1HAS2, LEPR, LEP, COL1A2
7MP:00053787.6HAS2, LEPR, LEP, PLAG1, COL1A2

Publications for Lipoblastoma

About this section

Articles related to Lipoblastoma:

(show top 50)    (show all 225)
idTitleAuthorsYear
1
Lipoblastoma and lipoblastomatosis of the lower leg. (25302126)
2014
2
An isolated digital lipoblastoma. (23789709)
2014
3
Recurrent lipoblastoma of upper extremity in a 9-year-old boy. (24713710)
2014
4
Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma. (24700772)
2014
5
Giant gluteal lipoblastoma associated with hepatic haemangioma and bilateral nephromegaly. (24849628)
2014
6
Desmin-positivity in spindle cells: under-recognized immunophenotype of lipoblastoma. (23865573)
2013
7
Diagnostic utility of molecular and cytogenetic analysis in lipoblastoma: a study of two cases and review of the literature. (24433523)
2013
8
A novel PLAG1-RAD51L1 gene fusion resulting from a t(8;14)(q12;q24) in a case of lipoblastoma. (23890983)
2013
9
Giant omental lipoblastoma and CD56 expression. (23519855)
2013
10
Intrascrotal lipoblastoma in a ten year old: case report and review of literature. (23772297)
2013
11
Multifocal lipoblastoma of the face. (23172486)
2012
12
A giant mesenteric lipoblastoma in an 18-month old infant: a case report and review of the literature. (22248900)
2011
13
Intrathoracic lipoblastoma in a 15-month-old infant. (22355506)
2011
14
A case of lipoblastoma with seven copies of chromosome 8. (19264235)
2009
15
Lipoblastoma--an unfamiliar but important diagnosis. A case series and literature review. (19774822)
2009
16
Mesenteric lipoblastoma presenting as a segmental volvulus. (19231517)
2009
17
Lipoblastoma on the posterior side of the neck. (19817275)
2009
18
Lipoblastoma in adolescents and young adults: report of six cases with FISH analysis. (18269579)
2008
19
Lipoblastoma in children: an analysis of 5 cases. (19051470)
2008
20
Lipoblastoma: appreciation of an expanded spectrum of disease through cytogenetic analysis. (18788858)
2008
21
Unusual breast enlargement in an infant: a case of breast lipoblastoma. (17051354)
2007
22
Congenital lipoblastoma in a neonate calf: first report in veterinary literature. (17355429)
2007
23
Benign intrascrotal lipoblastoma in a child. (17826513)
2007
24
Omental lipoblastoma. (18693617)
2007
25
Lipoblastoma and infantile lipoma. (17146210)
2006
26
A thoracic wall lipoblastoma in a 3-month-old infant: A case report and review of the literature. (17006266)
2006
27
Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology. (16308870)
2006
28
Lipoblastoma in a four-year-old African child. (16338874)
2005
29
Lipoblastoma of the neck mimicking cystic hygroma. (15746874)
2005
30
Lipoblastoma in an 11-month-old infant. (15322609)
2004
31
Intrascrotal lipoblastoma with a complex karyotype: a case report and review of the literature. (15214818)
2004
32
Axillary lipoblastoma--tumor recurrence in the right atrium. (12891504)
2003
33
Primary cardiac lipoblastoma. (11370265)
2001
34
PLAG1 fusion oncogenes in lipoblastoma. (10987300)
2000
35
Lipoblastoma with aberration in the long arm of chromosome 8. (10982693)
2000
36
A further case of chromosome 8q rearrangement in lipoblastoma. (11037871)
2000
37
Ruptured giant intrathoracic lipoblastoma in a 4-month-old infant: CT and MR findings. (10663508)
2000
38
Evidence by spectral karyotyping that 8q11.2 is nonrandomly involved in lipoblastoma. (11272891)
2000
39
"Lipoblastoma-like" lipoatrophy induced by human insulin: morphological evidence for local dedifferentiation of adipocytes? (10952472)
2000
40
Lipoblastoma: MRI appearances of a rare paediatric soft tissue tumour. (10398794)
1999
41
Lipoblastoma presenting as a mesenteric mass in an infant. (9856685)
1998
42
Chromosomal aberration in lipoblastoma: a case with 46,XX,ins(8;6)(q11.2;q13q27). (9169035)
1997
43
Lipoblastoma of the foot. (8741069)
1996
44
An unusual intrathoracic tumor: giant lipoblastoma. (7756235)
1995
45
New discriminative chromosomal marker in adipose tissue tumors. The chromosome 8q11-q13 region in lipoblastoma. (7828158)
1994
46
Potential diagnostic implications of breakpoints in the long arm of chromosome 8 in lipoblastoma. (8076349)
1994
47
Lipoblastoma and lipoblastomatosis--a report of six cases. (3413688)
1988
48
Benign lipoblastoma in the mandible. (6841120)
1983
49
Benign lipoblastoma in the neck causing respiratory insufficiency. (6865630)
1983
50
Benign lipoblastoma and myxoid liposarcoma: a comparative light- and electron-microscopic study. (7377463)
1980

Variations for Lipoblastoma

About this section

Expression for genes affiliated with Lipoblastoma

About this section
Expression patterns in normal tissues for genes affiliated with Lipoblastoma

Search GEO for disease gene expression data for Lipoblastoma.

Pathways for genes affiliated with Lipoblastoma

About this section

Pathways related to Lipoblastoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3LEP, LEPR
2
Show member pathways
Prolactin Signaling Pathway37
Development Prolactin receptor signaling60
Leptin signaling pathway37
9.3LEP, LEPR
3
Show member pathways
Type III interferon signaling37
9.3LEP, LEPR
49.3LEPR, LEP
59.3LEP, LEPR
6
Show member pathways
9.3LEP, LEPR
79.3LEP, LEPR
8
Show member pathways
9.3LEP, LEPR

Compounds for genes affiliated with Lipoblastoma

About this section

Compounds related to Lipoblastoma according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1ribonucleic acid4410.0COL1A2
2xbai449.8COL1A2, LEPR
3simvastatin44 50 61 28 24 1114.7COL1A2, LEPR
4lep (116-130) (mouse)619.7LEP, LEPR
5nash449.7LEP, LEPR
6olanzapine44 50 28 24 1113.7LEPR, LEP
7triacylglycerol449.7LEP, LEPR
8triiodothyronine449.6LEPR, LEP
9androstenedione44 2410.6LEP, LEPR
10corticosterone44 61 2411.6LEPR, LEP
11cocaine44 1110.6LEPR, LEP
12thyroxine44 2410.5LEPR, LEP
13hyaluronic acid44 2410.4LEP, HAS2
14prostacyclin449.4LEP, HAS2
15acth449.3LEPR, LEP
16gnrh449.2LEP, LEPR
17phosphatidylinositol449.1COL1A2, LEP, LEPR
18steroid449.1LEP, LEPR, HAS2
19estrogen449.1COL1A2, LEP, LEPR
20dexamethasone44 50 28 1112.1LEP, LEPR, HAS2
21cysteine449.1LEPR, LEP, COL1A2
22glucose449.0LEP, LEPR, HAS2
23lipid448.5LEP, LEPR, HAS2

GO Terms for genes affiliated with Lipoblastoma

About this section

Biological processes related to Lipoblastoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1energy reserve metabolic processGO:0061129.3LEP, LEPR
2regulation of blood pressureGO:0082179.3COL1A2, LEP
3cholesterol metabolic processGO:0082039.0LEP, LEPR

Products for genes affiliated with Lipoblastoma

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Lipoblastoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet