Aliases & Classifications for Lipoblastoma

MalaCards integrated aliases for Lipoblastoma:

Name: Lipoblastoma 49 55 69

Characteristics:

Orphanet epidemiological data:

55
lipoblastoma
Inheritance: Not applicable; Age of onset: Childhood;

Classifications:



External Ids:

Orphanet 55 ORPHA247762
UMLS via Orphanet 70 C1260965
UMLS 69 C1260965

Summaries for Lipoblastoma

MalaCards based summary : Lipoblastoma is related to lipomatosis, multiple and myxoid liposarcoma. An important gene associated with Lipoblastoma is HAS2 (Hyaluronan Synthase 2), and among its related pathways/superpathways are AMP-activated Protein Kinase (AMPK) Signaling and Relaxin signaling pathway. Affiliated tissues include breast, testes and bone, and related phenotypes are cardiovascular system and growth/size/body region

Wikipedia : 72 Lipoblastoma is a type of subcutaneous benign fatty... more...

Related Diseases for Lipoblastoma

Diseases related to Lipoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Related Disease Score Top Affiliating Genes
1 lipomatosis, multiple 30.2 CDK4 MDM2 PLAG1
2 myxoid liposarcoma 29.9 CDK4 MDM2
3 infiltrating lipoma 29.9 CDK4 MDM2
4 atypical lipomatous tumor 29.8 CDK4 MDM2 PLAG1
5 mediastinitis 10.3
6 cervicitis 10.3
7 larsen-like syndrome 10.2 COL1A2 COL3A1
8 ring chromosome 7 10.2 CDK4 MDM2
9 undifferentiated embryonal sarcoma of the liver 10.2 CDK4 MDM2
10 infiltrating angiolipoma 10.2 CDK4 MDM2
11 spindle cell lipoma 10.2 CDK4 MDM2
12 liposarcoma 10.2
13 extraosseous osteosarcoma 10.2 CDK4 MDM2
14 inflammatory mfh 10.2 CDK4 MDM2
15 bone osteosarcoma 10.2 CDK4 MDM2
16 mixed liposarcoma 10.2 CDK4 MDM2
17 malignant fibrous histiocytoma of bone 10.2 CDK4 MDM2
18 ischemic fasciitis 10.2 CDK4 MDM2
19 periosteal chondrosarcoma 10.2 CDK4 MDM2
20 ehlers-danlos syndrome, classic type, 1 10.2 COL1A2 COL3A1
21 periosteal osteogenic sarcoma 10.2 CDK4 MDM2
22 spindle cell liposarcoma 10.2 CDK4 MDM2
23 well-differentiated liposarcoma 10.2 CDK4 MDM2
24 chondroid lipoma 10.2 CDK4 MDM2
25 dedifferentiated liposarcoma 10.2 CDK4 MDM2
26 pleomorphic lipoma 10.1 CDK4 MDM2
27 small cell sarcoma 10.1 CDK4 MDM2
28 juxtacortical osteosarcoma 10.1 CDK4 MDM2
29 embryonal sarcoma 10.1 CDK4 MDM2
30 peripheral osteosarcoma 10.1 CDK4 MDM2
31 malignant fibroxanthoma 10.1 CDK4 MDM2
32 fibrosarcoma of bone 10.1 CDK4 MDM2
33 spondyloepiphyseal dysplasia congenita 10.1 COL1A2 COL3A1
34 malignant mesenchymoma 10.1 CDK4 MDM2
35 retinal cancer 10.1 CDK4 MDM2
36 grade iii astrocytoma 10.1 CDK4 MDM2
37 sensory system cancer 10.1 CDK4 MDM2
38 collagen disease 10.1 COL1A2 COL3A1
39 connective tissue cancer 10.0 CDK4 MDM2
40 intracranial aneurysm 10.0 COL1A2 COL3A1
41 idiopathic scoliosis 10.0 COL1A2 LEP
42 brittle bone disorder 9.9 COL1A2 COL3A1
43 hemangioma 9.9
44 severe pre-eclampsia 9.8 LEP LEPR
45 ossifying fibroma 9.7
46 cleft palate, isolated 9.7
47 glomuvenous malformations 9.7
48 intussusception 9.7
49 intestinal volvulus 9.7
50 testicular torsion 9.7

Graphical network of the top 20 diseases related to Lipoblastoma:



Diseases related to Lipoblastoma

Symptoms & Phenotypes for Lipoblastoma

MGI Mouse Phenotypes related to Lipoblastoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.98 CDK4 LEPR COL1A2 MDM2 COL3A1 HAS2
2 growth/size/body region MP:0005378 9.92 LEPR COL1A2 MDM2 COL3A1 PLAG1 HAS2
3 embryo MP:0005380 9.85 CDK4 LEPR MDM2 PLAG1 HAS2 LEP
4 digestive/alimentary MP:0005381 9.8 LEP CDK4 LEPR COL3A1 MDM2
5 integument MP:0010771 9.73 CDK4 LEPR COL1A2 MDM2 COL3A1 LEP
6 limbs/digits/tail MP:0005371 9.55 LEPR COL1A2 MDM2 HAS2 LEP
7 liver/biliary system MP:0005370 9.35 CDK4 LEPR COL3A1 MDM2 LEP
8 muscle MP:0005369 9.17 LEPR COL1A2 MDM2 COL3A1 HAS2 LEP

Drugs & Therapeutics for Lipoblastoma

Search Clinical Trials , NIH Clinical Center for Lipoblastoma

Genetic Tests for Lipoblastoma

Anatomical Context for Lipoblastoma

MalaCards organs/tissues related to Lipoblastoma:

38
Breast, Testes, Bone, Adipocyte, Colon, Small Intestine, Skin

Publications for Lipoblastoma

Articles related to Lipoblastoma:

(show top 50) (show all 260)
# Title Authors Year
1
Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature. ( 29343278 )
2018
2
Lipoblastoma-like Tumor of the Vulva, an Important Benign Mimic of Myxoid Liposarcoma. ( 29300200 )
2018
3
Current management of lipoblastoma. ( 29243188 )
2018
4
Mesenteric lipoblastoma presenting as a small intestinal volvulus in an infant: A case report and literature review. ( 28034384 )
2017
5
Varied Presentations of Pediatric Lipoblastoma: Case Series and Review of the Literature. ( 28111780 )
2017
6
Lipoblastoma in children: A review of 12 cases. ( 28083971 )
2017
7
Fine-needle aspiration of lipoblastoma: Cytological, molecular, and clinical features. ( 28902468 )
2017
8
A giant popliteal lipoblastoma in a 23-month-old girl: a case report. ( 29202860 )
2017
9
Submucosal Colonic Lipoblastoma Presenting With Colo-colonic Intussusception in an Infant. ( 28420321 )
2017
10
A Case of Orbital Lipoblastoma: Temporal Evolution of Imaging Findings. ( 28991355 )
2017
11
Analysis of clinical features of lipoblastoma in children. ( 29035641 )
2017
12
A Typical Case of Lipoblastoma on the Lower Limb of an Infant. ( 29195658 )
2017
13
Undifferentiated myxoid lipoblastoma with PLAG1-HAS2 fusion in an infant; morphologically mimicking primitive myxoid mesenchymal tumor of infancy (PMMTI)-diagnostic importance of cytogenetic and molecular testing and literature review. ( 26701195 )
2016
14
Lipoblastoma of the Labia: A Case Report. ( 27343432 )
2016
15
Lipoblastoma presenting as a rapidly growing paravertebral mass and masquerading as myxoid liposarcoma on fine needle aspiration cytology. ( 26919610 )
2016
16
Lipoblastomatosis of the retropharyngeal space: pathogenesis, presentation, and management, with a focus on head-neck lipoblastoma(toses). ( 27097392 )
2016
17
Intrascrotal lipoblastoma: report of a case and the review of literature. ( 27059472 )
2016
18
Case report of a forearm lipoblastoma. ( 27773114 )
2016
19
Spinal dumbbell lipoblastoma: a case-based update. ( 27444294 )
2016
20
Lipoblastoma: an unusual tumour of the left ventricle. ( 26819289 )
2016
21
Immunohistochemical expression of p16 in lipoblastomas. ( 26514741 )
2016
22
Lipoblastoma and lipoblastomatosis: A clinicopathological study of six cases. ( 26881660 )
2015
23
A rare cause of horner syndrome: pediatric lipoblastoma of the neck. ( 25974809 )
2015
24
A Massive Intratumoral Aneurysmal Vessel in a Retroperitoneal Lipoblastoma. ( 26730109 )
2015
25
Intradermal Lipoblastoma-Like Tumor of the Lip in an Adult Woman. ( 26358498 )
2015
26
Cervical lipoblastoma: An uncommon presentation. ( 26214680 )
2015
27
Lipoblastoma mimicking inguinal hernia. ( 25628996 )
2015
28
Huge Mediastinal Lipoblastoma in a Nine Year-old Boy Successfully Removed Surgically. ( 25800538 )
2015
29
Lipoblastoma-like tumor of the vulva: further characterization in 8 new cases. ( 25929353 )
2015
30
An unusual case of cervical lipoblastoma with review of literature. ( 26881589 )
2015
31
Successful laparoscopic extirpation of a large omental lipoblastoma in a child. ( 26708589 )
2015
32
Surgical and Anesthetic Management of a Mediastinal Fatty Tumor: Lipoblastoma. ( 26522578 )
2015
33
A case of unusual histology of infantile lipoblastoma confirmed by PLAG1 rearrangement. ( 26943407 )
2015
34
Lipoblastoma of the hand and cleft palate: is there a genetic association? ( 24621768 )
2014
35
Perineal lipoblastoma: a case report and review of literature. ( 25031762 )
2014
36
Primary spinal extradural lipoblastoma: Rare occurrence. ( 25624950 )
2014
37
Lipoblastoma in childhood: about 10 cases. ( 24647290 )
2014
38
An isolated digital lipoblastoma. ( 23789709 )
2014
39
A giant omental Lipoblastoma in a four-year-old boy. ( 24955971 )
2014
40
Pediatric neck mass. Right deep cervical lipoblastoma. ( 24385017 )
2014
41
Aspiration cytology diagnosis of lipoblastoma of the back. ( 25057474 )
2014
42
Mesenteric lipoblastoma and cervical lipoblastomatosis: ultrasound, elastosonography, and computed tomography findings in two children. ( 24795830 )
2014
43
Recurrent lipoblastoma of upper extremity in a 9-year-old boy. ( 24713710 )
2014
44
Giant gluteal lipoblastoma associated with hepatic haemangioma and bilateral nephromegaly. ( 24849628 )
2014
45
Lipoblastoma and lipoblastomatosis of the lower leg. ( 25302126 )
2014
46
Identification of COL3A1 and RAB2A as novel translocation partner genes of PLAG1 in lipoblastoma. ( 24700772 )
2014
47
Giant omental lipoblastoma and CD56 expression. ( 23519855 )
2013
48
Desmin-positivity in spindle cells: under-recognized immunophenotype of lipoblastoma. ( 23865573 )
2013
49
Intrascrotal lipoblastoma in a ten year old: case report and review of literature. ( 23772297 )
2013
50
Diagnostic utility of molecular and cytogenetic analysis in lipoblastoma: a study of two cases and review of the literature. ( 24433523 )
2013

Variations for Lipoblastoma

Expression for Lipoblastoma

Search GEO for disease gene expression data for Lipoblastoma.

Pathways for Lipoblastoma

GO Terms for Lipoblastoma

Biological processes related to Lipoblastoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.71 CDK4 HAS2 LEP MDM2
2 cellular response to amino acid stimulus GO:0071230 9.54 COL1A2 COL3A1
3 collagen fibril organization GO:0030199 9.52 COL1A2 COL3A1
4 negative regulation of autophagy GO:0010507 9.51 LEP LEPR
5 positive regulation of cell cycle GO:0045787 9.49 CDK4 MDM2
6 T cell differentiation GO:0030217 9.48 LEP LEPR
7 adipose tissue development GO:0060612 9.46 CDK4 LEP
8 negative regulation of cell cycle arrest GO:0071157 9.43 CDK4 MDM2
9 energy reserve metabolic process GO:0006112 9.37 LEP LEPR
10 sexual reproduction GO:0019953 9.32 LEP LEPR
11 leptin-mediated signaling pathway GO:0033210 9.26 LEP LEPR
12 regulation of bone remodeling GO:0046850 9.16 LEP LEPR
13 blood vessel development GO:0001568 9.13 COL1A2 COL3A1 MDM2
14 bone growth GO:0098868 8.62 LEP LEPR

Molecular functions related to Lipoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 SMAD binding GO:0046332 8.96 COL1A2 COL3A1
2 platelet-derived growth factor binding GO:0048407 8.62 COL1A2 COL3A1

Sources for Lipoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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