MCID: LPD011
MIFTS: 61

Lipoid Adrenal Hyperplasia malady

Categories: Genetic diseases, Rare diseases, Reproductive diseases, Endocrine diseases, Fetal diseases, Metabolic diseases

Aliases & Classifications for Lipoid Adrenal Hyperplasia

About this section
Sources:
11Disease Ontology, 12diseasecard, 13DISEASES, 24GeneTests, 26GTR, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 36MedGen, 38MeSH, 39MESH via Orphanet, 47NIH Rare Diseases, 49Novoseek, 51OMIM, 53Orphanet, 61SNOMED-CT, 63The Human Phenotype Ontology, 67UMLS, 68UMLS via Orphanet, 69UniProtKB/Swiss-Prot
See all MalaCards sources

Aliases & Descriptions for Lipoid Adrenal Hyperplasia:

Name: Lipoid Adrenal Hyperplasia 51 12
Congenital Adrenal Hyperplasia 11 47 24 26 13 67
Lipoid Congenital Adrenal Hyperplasia 51 47 49 67
Congenital Lipoid Adrenal Hyperplasia 11 47 69
Lipoid Cah 11 47 69
Congenital Lipoid Adrenal Hyperplasia Due to Star Deficency 47 53
Adrenal Hyperplasia 1 11 69
Clah 47 53
 
Cah 47 24
Congenital Lipoid Hyperplasia of Adrenal Cortex with Male Pseudohermaphroditism 69
Congenital Adrenal Hyperplasia Lipoid 47
Adrenal Hyperplasia, Congenital 38
Adrenal Hyperplasia Congenital 49
Chronic Active Hepatitis 67
Ah1 69

Characteristics:

Orphanet epidemiological data:

53
congenital lipoid adrenal hyperplasia due to star deficency:
Inheritance: Autosomal recessive; Age of onset: Infancy,Neonatal

HPO:

63
lipoid adrenal hyperplasia:
Inheritance: autosomal recessive inheritance

Classifications:



External Ids:

OMIM51 201710
Disease Ontology11 DOID:0050811
ICD1029 E25, E25.9
ICD9CM31 255.2
Orphanet53 ORPHA90790
MESH via Orphanet39 C537027
UMLS via Orphanet68 C0342474
ICD10 via Orphanet30 E25.0
MedGen36 C0342474
MeSH38 D000312
UMLS67 C0701163

Summaries for Lipoid Adrenal Hyperplasia

About this section
UniProtKB/Swiss-Prot:69 Adrenal hyperplasia 1: The most severe form of adrenal hyperplasia. It is a condition characterized by onset of profound adrenocortical insufficiency shortly after birth, hyperpigmentation reflecting increased production of pro-opiomelanocortin, elevated plasma renin activity as a consequence of reduced aldosterone synthesis, and male pseudohermaphroditism resulting from deficient fetal testicular testosterone synthesis. Affected individuals are phenotypic females irrespective of gonadal sex, and frequently die in infancy if mineralocorticoid and glucocorticoid replacement are not instituted.

MalaCards based summary: Lipoid Adrenal Hyperplasia, also known as congenital adrenal hyperplasia, is related to non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency and classic congenital lipoid adrenal hyperplasia due to star deficency, and has symptoms including cryptorchidism, hypertension and hypercortisolism. An important gene associated with Lipoid Adrenal Hyperplasia is STAR (Steroidogenic Acute Regulatory Protein), and among its related pathways are Ovarian steroidogenesis and Insulin secretion. The drugs hydrocortisone pwdr and hydrocortisone cypionate have been mentioned in the context of this disorder. Affiliated tissues include ovary, cortex and adrenal cortex, and related mouse phenotypes are endocrine/exocrine gland and reproductive system.

Disease Ontology:11 A steroid inherited metabolic disorder that is characterized by adrenal insufficiency and variable degrees of hyper or hypo androgeny manifestations resulting from steroidogenic enzyme deficiency.

OMIM:51 Lipoid congenital adrenal hyperplasia, the most severe disorder of steroid hormone biosynthesis, is caused by a defect... (201710) more...

Related Diseases for Lipoid Adrenal Hyperplasia

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Diseases related to Lipoid Adrenal Hyperplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 53)
idRelated DiseaseScoreTop Affiliating Genes
1non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency12.2
2classic congenital lipoid adrenal hyperplasia due to star deficency12.1
3non-classic congenital lipoid adrenal hyperplasia due to star deficency12.1
4classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency12.1
5adrenal hyperplasia, congenital, due to 11-beta-hydroxylase deficiency11.6
6acth-independent macronodular adrenal hyperplasia11.6
7cholesterol desmolase-deficient congenital adrenal hyperplasia11.3
8adrenal insufficiency, congenital, with 46xy sex reversal, partial or complete11.3
9adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency11.1
10actinic lichen planus10.4POMC, STAR
11hidradenocarcinoma10.4CYP21A2, POMC
12mite infestation10.4CYP21A2, STAR
13duchenne muscular dystrophy10.3NR5A1, STAR
14gallbladder adenoma10.3NR5A1, POMC
15spastic paraplegia 45, autosomal recessive10.2CYP17A1, POR
16dressler's syndrome10.2CYP11A1, CYP21A2, POMC
17klinefelter's syndrome10.2NR5A1, STAR
18chancroid10.2CYP11A1, CYP21A2, POMC
19adrenal carcinoma10.1CYP21A2, POMC
20centrotemporal epilepsy10.1CYP11A1, NR5A1, POMC
21keratoacanthoma10.1CYP21A2, POMC
22vaginal discharge10.1CYP17A1, HSD3B2
23lateral sclerosis10.1CYP17A1, NR5A1, POMC
24ovarian cyst10.0
25drug-induced mental disorder10.0CYP11B1, CYP11B2, POMC
26precursor b lymphoblastic lymphoma/leukemia9.9CYP11A1, CYP17A1, HSD3B2
27hypoaldosteronism, congenital, due to cmo ii deficiency9.9CYP11B1, CYP11B2, POMC
28acute myocarditis9.9CYP11B1, CYP11B2, POMC
29loeffler endocarditis9.9CYP11B1, CYP11B2, POMC
30nasopharyngeal disease9.9CYP11B1, CYP11B2, POMC
31cardiovascular organ benign neoplasm9.9CYP11B1, CYP11B2, POMC
32collecting duct carcinoma9.9CYP11B1, CYP11B2, POMC
33sporotrichosis9.9C4A, POMC
3446 xx gonadal dysgenesis9.9CYP11A1, CYP17A1, NR5A1, STAR
35vestibular gland benign neoplasm9.9CYP11B1, CYP11B2, POMC
36cholestasis9.9
37familial glucocorticoid deficiency9.9
38hidradenitis9.8NR5A1, POMC
39malakoplakia9.8CYP17A1, HSD3B1
40hepatitis c virus9.8
41hepatitis9.8
42hepatitis c9.8
43dfna2 nonsyndromic hearing loss9.8CYP17A1, CYP21A2, POMC, POR
44tooth disease9.7CYP11A1, CYP17A1, HSD3B2, NR5A1
45pfeiffer syndrome9.6CYP11A1, NR5A1, POMC, POR, STAR
46dental pulp necrosis9.5CYP11A1, CYP17A1, CYP21A2, HSD3B2, POMC
47glioma susceptibility 19.4CYP11A1, CYP11B1, CYP11B2, NR5A1, POMC
48neurilemmoma of the pleura9.1CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP21A2, POMC
49adrenal cortex disease9.1CYP11A1, CYP11B1, CYP17A1, CYP21A2, NR5A1, POMC
50vasculogenic impotence9.0CYP11A1, CYP17A1, CYP21A2, HSD3B1, POMC, STAR

Graphical network of the top 20 diseases related to Lipoid Adrenal Hyperplasia:



Diseases related to lipoid adrenal hyperplasia

Symptoms for Lipoid Adrenal Hyperplasia

About this section

Symptoms by clinical synopsis from OMIM:

201710

Clinical features from OMIM:

201710

Human phenotypes related to Lipoid Adrenal Hyperplasia:

 63 53 (show all 58)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 cryptorchidism63 53 hallmark (90%) Very frequent (99-80%) HP:0000028
2 hypertension63 hallmark (90%) HP:0000822
3 hypercortisolism63 hallmark (90%) HP:0001578
4 abnormality of metabolism/homeostasis63 hallmark (90%) HP:0001939
5 accelerated skeletal maturation63 hallmark (90%) HP:0005616
6 female pseudohermaphroditism63 hallmark (90%) HP:0010458
7 displacement of the external urethral meatus63 hallmark (90%) HP:0100627
8 hypospadias63 HP:0000047
9 renal salt wasting63 53 Very frequent (99-80%) HP:0000127
10 adrenogenital syndrome63 53 Very frequent (99-80%) HP:0000840
11 congenital adrenal hyperplasia63 53 Very frequent (99-80%) HP:0008258
12 ambiguous genitalia, male53 Very frequent (99-80%)
13 male pseudohermaphroditism53 Very frequent (99-80%)
14 abnormality of the menstrual cycle53 Very frequent (99-80%)
15 abnormality of the vagina53 Very frequent (99-80%)
16 decreased fertility53 Very frequent (99-80%)
17 gynecomastia53 Very frequent (99-80%)
18 delayed puberty53 Very frequent (99-80%)
19 increased circulating renin level53 Very frequent (99-80%)
20 decreased fertility in females53 Very frequent (99-80%)
21 delayed skeletal maturation53 Very frequent (99-80%)
22 primary adrenal insufficiency53 Very frequent (99-80%)
23 osteoporosis53 Very frequent (99-80%)
24 abnormality of prenatal development or birth53 Very frequent (99-80%)
25 failure to thrive53 Very frequent (99-80%)
26 short stature53 Very frequent (99-80%)
27 acidosis53 Very frequent (99-80%)
28 dehydration53 Very frequent (99-80%)
29 vomiting53 Very frequent (99-80%)
30 neonatal hypoglycemia53 Very frequent (99-80%)
31 hyperkalemia53 Very frequent (99-80%)
32 hypotension53 Very frequent (99-80%)
33 hyponatremia53 Very frequent (99-80%)
34 decreased circulating aldosterone level53 Very frequent (99-80%)
35 abnormality of cholesterol metabolism53 Very frequent (99-80%)
36 hypercholesterolemia53 Very frequent (99-80%)
37 increased circulating acth level53 Very frequent (99-80%)
38 hypernatriuria53 Very frequent (99-80%)
39 reduced bone mineral density53 Very frequent (99-80%)
40 generalized hyperpigmentation53 Very frequent (99-80%)
41 decreased circulating cortisol level53 Very frequent (99-80%)
42 absence of secondary sex characteristics53 Very frequent (99-80%)
43 adrenocortical adenoma53 Very frequent (99-80%)
44 elevated follicle stimulating hormone53 Very frequent (99-80%)
45 abnormal spermatogenesis53 Very frequent (99-80%)
46 decreased testicular size53 Very frequent (99-80%)
47 female external genitalia in individual with 46,xy karyotype53 Very frequent (99-80%)
48 hypovolemia53 Very frequent (99-80%)
49 ectopic adrenal gland53 Very frequent (99-80%)
50 adrenocorticotropic hormone excess53 Very frequent (99-80%)
51 feeding difficulties53 Very frequent (99-80%)
52 elevated luteinizing hormone53 Very frequent (99-80%)
53 decreased fertility in males53 Very frequent (99-80%)
54 abnormal sex determination53 Very frequent (99-80%)
55 sex reversal53 Very frequent (99-80%)
56 decreased circulating androgen level53 Very frequent (99-80%)
57 abnormal urine potassium concentration53 Very frequent (99-80%)
58 urogenital sinus anomaly53 Very frequent (99-80%)

Drugs & Therapeutics for Lipoid Adrenal Hyperplasia

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Drugs for Lipoid Adrenal Hyperplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 176)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Hydrocortisoneapproved, vet_approvedPhase 4, Phase 3, Phase 2, Phase 164050-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
2
Estradiolapproved, investigational, vet_approvedPhase 4, Phase 2128350-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol [USAN:INN]
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
Estrofem Forte
Estrogel
 
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
3
Ethinyl EstradiolapprovedPhase 4, Phase 271257-63-65991
Synonyms:
17 alpha-Ethinylestradiol
17 alpha-Ethynylestradiol
17 alpha-Ethynyloestradiol
17 alpha-ethinyestradiol
17-Ethinyl-3,17-estradiol
17-Ethinyl-3,17-oestradiol
17-Ethinylestradiol
17-Ethynylestradiol
17-Ethynylestradiol ram
17-Ethynyloestradiol
17-alpha-Ethinyl-17-beta-estradiol
17-alpha-Ethynyl-17-beta-oestradiol
17-alpha-Ethynylestradiol
17-alpha-Ethynylestradiol-17-beta
17-alpha-ethynyl estradiol
17-ethinyl-3,17-estradiol
17-ethinyl-3,17-oestradiol
17-ethinylestradiol
17.alpha.-Ethinyl-17.beta.-estradiol
17.alpha.-Ethinylestradiol
17.alpha.-Ethynyl-17.beta.-oestradiol
17.alpha.-Ethynylestradiol
17.alpha.-Ethynylestradiol-l7.beta.
17.alpha.-Ethynyloestradiol
17.alpha.-Ethynyloestradiol-17.beta.
17a-Ethinyl-17b-estradiol
17a-Ethinylestradiol
17a-Ethynyl-17b-oestradiol
17a-Ethynylestradiol
17a-Ethynylestradiol-l7b
17a-Ethynyloestradiol
17a-Ethynyloestradiol-17b
17alpha-Ethinyl estradiol
17alpha-Ethinylestradiol
17alpha-Ethinylestradiol-17beta
17alpha-Ethynylestradiol
17alpha-Ethynyloestradiol
17alpha-Ethynyloestradiol-17beta
17α-ethynylestradiol
406932-93-2
46263_FLUKA
46263_RIEDEL
57-63-6
77538-56-8
AC-2169
AC1L1LK6
AI3-52941
Aethinyloestradiolum
Aethinyoestradiol
Aethinyoestradiol [German]
Alora
Amenoron
Amenorone
Anovlar
BIDD:ER0162
BRN 2419975
Bio-0610
C07534
CCRIS 286
CHEBI:4903
CHEMBL691
CID5991
CPD000058319
Certostat
Chee-O-Gen
Chee-O-Genf
Cyclosa
D004997
D00554
DB00977
Dicromil
Diognat-E
Diogyn E
Diogyn-E
Diprol
Dyloform
E4876_SIGMA
EE
EE(sub 2)
EE2
EINECS 200-342-2
EO
ETHINYLESTRADIOL
Effik Brand of Ethinyl Estradiol
Ertonyl
Esclim
Esteed
Estigyn
Estinyl
Estinyl (TN)
Eston-E
Estopherol
Estoral
Estoral (Orion)
Estoral (VAN)
Estoral [Orion]
Estoral {[Orion]}
Estorals
Estradiol, Ethinyl
Estradiol, Ethynyl
Estring
Estrogen
Ethidol
Ethinoral
Ethinyl E2
Ethinyl Estradiol Hemihydrate
Ethinyl Estradiol [USP]
 
Ethinyl Estradiol, (8 alpha)-Isomer
Ethinyl Oestradiol Effik
Ethinyl estradiol
Ethinyl estradiol (USP)
Ethinyl-Oestradiol Effik
Ethinyl-Oestranol
Ethinyl-oestranol
Ethinylestradiol
Ethinylestradiol (JP15/INN)
Ethinylestradiol Jenapharm
Ethinylestradiol [INN:BAN:JAN]
Ethinylestradiolum
Ethinylestradiolum [INN-Latin]
Ethinylestriol
Ethinyloestradiol
Ethinyloestradiol [Steroidal oestrogens]
Ethy 11
Ethynyl estradiol
Ethynylestradiol
Ethynylestradiol, Ethinyl Estradiol
Ethynyloestradiol
Eticyclin
Eticyclol
Eticylol
Etinestrol
Etinestryl
Etinilestradiol
Etinilestradiol [INN-Spanish]
Etinilestradiolo
Etinilestradiolo [DCIT]
Etinoestryl
Etistradiol
Etivex
Evra
Feminone
Fempatch
Follicoral
Ginestrene
Gynodiol
Gynolett
HMS2051I19
HSDB 3587
Halodrin
Hemihydrate, Ethinyl Estradiol
Inestra
Innofem
Jenapharm Brand of Ethinyl Estradiol
Jenapharm, Ethinylestradiol
Kolpolyn
LMST02010036
LS-231
Linoral
Lynoral
MLS000028479
MLS000758274
Marvelon
Menolyn
Menostar
Mercilon
Microfollin
Microfollin Forte
MolPort-001-794-636
NCGC00091533-01
NCGC00091533-04
NCGC00091533-05
NCI60_000234
NSC-10973
NSC10973
Neo-Estrone
Nogest-S
Novestrol
OVULEN-21
OVULEN-28
Oradiol
Orestralyn
Orestrayln
Organon Brand of Ethinyl Estradiol
Ortho-Cyclen
Ovex
Oviol
PUBERTAL ETHINYL ESTRADIOL STUDY
Palonyl
Perovex
Primogyn
Primogyn C
Primogyn M
Progynon C
Progynon M
Prosexol
S1625_Selleck
SAM001247008
SGCUT00127
SMR000058319
Schering Brand of Ethinyl Estradiol
Spanestrin
Thiuram E
Thiuranide
UNII-423D2T571U
Vagifem
Varnoline
WLN: L E5 B666TTT&J E1 FQ F1UU1 OQ
Ylestrol
component of Demulen
component of Oracon
component of Ortrel
ethinyl estradiol
ethynyl estradiol
to_000048
4
DrospirenoneapprovedPhase 410267392-87-468873
Synonyms:
(6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-Hexadecahydro-10,13-dimethylspiro-(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione
1, 2-Dihydrospirorenone
1,2-Dihydrospirorenone
1,2-dihydro-spirorenone
15,16]-17alpha-pregn-4-ene-21,17-carbolactone
15-beta,16-beta-Dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactone
15beta,16beta-Dimethylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
17-Hydroxy-6beta,7beta:15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone
3-oxo-6alpha,7alpha,15alpha,16alpha-tetrahydro-7'H,16'H-dicyclopropa[6,7
6-beta,7-beta
67392-87-4
6beta,7Beta
6beta,7beta
6beta,7beta,15beta,16beta-dimethylen-3-oxo-17alpha-pregn-4-en-21,17-carbolacton
6beta,7beta,15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21,17 carbolactone
6β,7β,15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17 carbolactone
AC1L2AMM
Angeliq, Drospirenone
BRN 4765500
C035144
C24H30O3
CCRIS 6523
CHEBI:50838
 
CHEMBL1509
CID68873
D03917
DB01395
DRSP
Dehydrospirorenone
Dihydrospirorenone
Drospirenona
Drospirenona [INN-Spanish]
Drospirenona [inn-spanish]
Drospirenone
Drospirenone (JAN/USAN/INN)
Drospirenone [INN]
Drospirenonum
Drospirenonum [INN-Latin]
Drospirenonum [inn-latin]
EINECS 266-679-2
LS-146115
S1377_Selleck
SH-470
Spiro(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione, 1,3',4',6,7,8,9,10,11,12,13,14,15,16,20,21-hexadecahydro-10,13-dimethyl-, (6R-(6alpha,7alpha,8beta,9alpha,10beta,13beta,14alpha,15alpha,16alpha,17beta
UNII-N295J34A25
ZINC03927200
ZK 30595
ZK-30595
ZK30595
5
Cyproterone Acetateapproved, investigationalPhase 441427-51-0
Synonyms:
 
Cyproterone 17-O-acetate
6
CosyntropinapprovedPhase 42416960-16-016129617
Synonyms:
16960-16-0
ATCH (1-24)
Adrenocorticotropic hormone fragment 1-24 human, rat
COSYNTROPIN
Corticotropin tetracosapeptide
Cortrosyn
Cortrosyn (TN)
Cosyntropin
Cosyntropin (USAN)
 
D00284
Tetracosactide
Tetracosactide (INN)
Tetracosactrin
adrenocorticotropic hormone 1-24
alpha(1-24)-corticotrophin
beta(1-24)-corticotrophin
corticotropin-(1-24)
corticotropin-(1-24) tetracosapeptide
α1-24-corticotrophin
β1-24-corticotrophin
7
Epinephrineapproved, vet_approvedPhase 4, Phase 3, Phase 2, Phase 193351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
8
MetforminapprovedPhase 4, Phase 3, Phase 21746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
9
Folic Acidapproved, nutraceutical, vet_approvedPhase 4427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
10Diuretics, Potassium SparingPhase 41827
11Estradiol 3-benzoatePhase 4, Phase 21283
12Drospirenone and ethinyl estradiol combinationPhase 483
13Estradiol valeratePhase 4, Phase 21283979-32-8
14Estradiol 17 beta-cypionatePhase 4, Phase 21283
15MineralocorticoidsPhase 4, Phase 3, Phase 2352
16Protective AgentsPhase 47190
17Anti-Inflammatory AgentsPhase 4, Phase 2, Phase 3, Phase 110355
18Polyestradiol phosphatePhase 4, Phase 21283
19Natriuretic AgentsPhase 41645
20Mineralocorticoid Receptor AntagonistsPhase 4, Phase 3333
21diureticsPhase 41372
22HemostaticsPhase 41359
23EstrogensPhase 4, Phase 3, Phase 22470
24Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112767
25Hydrocortisone 17-butyrate 21-propionatePhase 4, Phase 3, Phase 2, Phase 1640
26Hydrocortisone acetatePhase 4, Phase 3, Phase 2, Phase 1640
27HormonesPhase 4, Phase 3, Phase 2, Phase 113979
28Epinephryl boratePhase 4, Phase 3, Phase 2, Phase 1933
29Cyproterone acetate, ethinyl estradiol drug combinationPhase 48
30Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 112778
31Androgen AntagonistsPhase 4, Phase 2, Phase 1308
32RacepinephrinePhase 4, Phase 3, Phase 2, Phase 1933
33Contraceptives, OralPhase 4, Phase 21292
34Contraceptives, Oral, CombinedPhase 4, Phase 2625
35
CyproteronePhase 4412098-66-05284537
Synonyms:
(1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one
2098-66-0
6-Chlor-delta(6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron
6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron
6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron [German]
6-chloro-17-hydroxy-1beta,2beta-dihydro-3'H-cyclopropa[1,2]pregna-4,6-diene-3,20-dione
AC-6213
AC1L1EZB
AC1L27WO
Apo-cyproterone
BAY 94-8367
BAY94-8367
BSPBio_003462
C22H27ClO3
CHEBI:50742
CHEMBL142130
CID10044976
CID16417
CID3015
CID5284537
CID5702275
Ciproterona
Ciproterona Servycal
Ciproterona Servycal (TN)
Ciproterona [INN-Spanish]
Ciproterone
Ciproterone [DCIT]
CyPat
Cyproteron
Cyproterone (INN)
Cyproterone [INN:BAN]
 
Cyproterone acetate
Cyproteronum
Cyproteronum [INN-Latin]
D07766
DB04839
DivK1c_000786
Gen-Cyproterone
HMS1922K16
HMS502H08
IDI1_000786
KBio1_000786
KBio2_002052
KBio2_004620
KBio2_007188
KBio3_002966
KBioGR_001485
KBioSS_002052
LS-58798
MolPort-003-981-177
MolPort-005-932-862
NCGC00178048-01
NINDS_000786
Novo-cyproterone
SH 80881
SPBio_001594
SPECTRUM1503921
Spectrum2_001597
Spectrum3_001901
Spectrum4_000853
Spectrum5_001362
Spectrum_001572
UNII-E61Q31EK2F
cyproterone
36AndrogensPhase 4, Phase 3, Phase 2, Phase 11275
37Contraceptive Agents, MalePhase 4224
38Contraceptive AgentsPhase 4, Phase 21901
39Cortisol succinatePhase 4, Phase 3, Phase 2, Phase 1640
40AntioxidantsPhase 42928
41Vitamin B ComplexPhase 44229
42Trace ElementsPhase 45802
43VitaminsPhase 45095
44Hypoglycemic AgentsPhase 4, Phase 3, Phase 25733
45HematinicsPhase 41630
46MicronutrientsPhase 45802
47Calcium, DietaryPhase 4, Phase 3, Phase 1, Phase 25525
48Vitamin B9NutraceuticalPhase 44279
49FolateNutraceuticalPhase 44279
50Folinic AcidNutraceuticalPhase 43150

Interventional clinical trials:

(show top 50)    (show all 85)
idNameStatusNCT IDPhase
1Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen TestUnknown statusNCT00851942Phase 4
2Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by AntioxidantsUnknown statusNCT02027337Phase 4
3Ethinyl Estradiol and Cyproterone Acetate in Irregular MenstruationUnknown statusNCT01103518Phase 4
4Low Dose OC Therapy in Women With Polycystic Ovary Syndrome (PCOS): Impact of BMI on HyperandrogenismCompletedNCT01360996Phase 4
5Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOSCompletedNCT00428311Phase 4
6SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan.CompletedNCT01096654Phase 3
7Effect of a Commonly Used Antibiotic, Doxycycline, in Women With Polycystic Ovarian SyndromeCompletedNCT01788215Phase 3
8The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory WomenCompletedNCT00413179Phase 3
9COrticosteroid in Congenital Adrenal HyperplasiaRecruitingNCT02552251Phase 2, Phase 3
10Comparison of Chronocort® With Standard Glucocorticoid Therapy in Patients With Congenital Adrenal HyperplasiaRecruitingNCT02716818Phase 3
11Extension Study for Patients Entered Into Study Infacort 003RecruitingNCT02733367Phase 3
12Dynamic Hormone Diagnostics in Endocrine DiseaseNot yet recruitingNCT02934399Phase 2, Phase 3
13Dexamethasone Treatment of Congenital Adrenal HyperplasiaCompletedNCT00621985Phase 2
14Pilot Study to Characterize and Examine the Pharmacokinetics and Efficacy of Chronocort® in Adults With CAHCompletedNCT01735617Phase 2
15Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal HyperplasiaCompletedNCT01859312Phase 2
16Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal HyperplasiaCompletedNCT00519818Phase 1, Phase 2
17Congenital Adrenal Hyperplasia: Calcium Channels as Therapeutic TargetsCompletedNCT00000102Phase 1, Phase 2
18Phase II Randomized Study of Leuprolide Vs Oral Contraceptive Therapy Vs Leuprolide and Oral Contraceptive Therapy for Ovarian HyperandrogenismCompletedNCT00004763Phase 2
19Treatment of Hyperandrogenism Versus Insulin Resistance in Infertile Polycystic Ovary Syndrome (PCOS) WomenCompletedNCT00704912Phase 2
20Continuous Subcutaneous Hydrocortisone Infusion in Congenital Adrenal HyperplasiaRecruitingNCT01771328Phase 2
21A Study of ATR-101 for the Treatment of Congenital Adrenal HyperplasiaRecruitingNCT02804178Phase 2
22Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal HyperplasiaRecruitingNCT02096510Phase 1, Phase 2
23Study of Efficacy and Safety of Osilodrostat in Cushing's SyndromeRecruitingNCT02468193Phase 2
24Acupuncture or Metformin for Insulin Resistance in Women With PCOSRecruitingNCT02647827Phase 2
25Androgen Excess as a Mechanism for Adipogenic Dysfunction in PCOS WomenRecruitingNCT01889199Phase 2
26Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin ResistantEnrolling by invitationNCT02523898Phase 2
27Ulipristal Acetate In Disease Charcot-Marie-Tooth Type of 1ANot yet recruitingNCT02600286Phase 2
28A Study Examining Doses of Abiraterone Acetate in Adult Women With 21-Hydroxylase DeficiencyCompletedNCT01495910Phase 1
29Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal HyperplasiaCompletedNCT00001521Phase 1
30An Open Label Study in Healthy Volunteers to Compare Chronocort® to HydrocortisoneCompletedNCT03019614Phase 1
31Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1Not yet recruitingNCT02574910Phase 1
32Safety, Pharmacokinetics and Pharmacodynamics of NBI-77860 in Adolescent Females With Congenital Adrenal HyperplasiaWithdrawnNCT02349503Phase 1
33Role of the Protein Osteoprotegerin in the Bone Health of Women With Congenital Adrenal HyperplasiaUnknown statusNCT00694525
34Determining the Long-Term Effects of Prenatal Dexamethasone Treatment in Children With 21-Hydroxylase Deficiency and Their MothersUnknown statusNCT00617292
35Tweens to Teens Project at Penn StateUnknown statusNCT01184651
36Mutation Analysis of 17α-HydroxylaseUnknown statusNCT00172510
37Meal Timing on Glucose and Hyperandrogenism in PCOS WomenUnknown statusNCT01711476
38Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary SyndromeUnknown statusNCT00665171
39Research Study for Children With Salt Wasting Congenital Adrenal HyperplasiaCompletedNCT00529841
40Examining Genetic Differences Among People With 21-Hydroxylase DeficiencyCompletedNCT00542841
41Study of UK Adults With Congenital Adrenal Hyperplasia.CompletedNCT00749593
42Cardiovascular Risk Profile in Patients With Congenital Adrenal HyperplasiaCompletedNCT01807364
43Qualitative Research on Women With Congenital Adrenal HyperplasiaCompletedNCT00559078
44Effects of Pioglitazone in Congenital Adrenal HyperplasiaCompletedNCT00151710
45Catecholamine Reserve and Exercise Tolerance in Healthy Volunteers and Patients With Congenital Adrenal HyperplasiaCompletedNCT00011791
46Adrenal Hyperplasia Among Young People With PCOSCompletedNCT01313455
47Clinical Evaluation of NeoPlex4 Assay and NeoPlex SystemCompletedNCT01488721
48Arterial Stiffness Index as a Predictor of Surgically Correctable Primary AldosteronismCompletedNCT01190501
49Primary Aldosteronism in General Practice: Organ Damage, Epidemiology and TreatmentCompletedNCT01728493
50Biochemical and Radiological Indicators of Cardiovascular Morbidity in Children With Premature PubarcheCompletedNCT00581490

Search NIH Clinical Center for Lipoid Adrenal Hyperplasia

Inferred drug relations via UMLS67/NDF-RT45:

Show with subtypes


Cochrane evidence based reviews: adrenal hyperplasia, congenital

Genetic Tests for Lipoid Adrenal Hyperplasia

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Genetic tests related to Lipoid Adrenal Hyperplasia:

id Genetic test Affiliating Genes
1 Congenital Adrenal Hyperplasia26 24

Anatomical Context for Lipoid Adrenal Hyperplasia

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MalaCards organs/tissues related to Lipoid Adrenal Hyperplasia:

35
Ovary, Cortex, Adrenal cortex, Bone, Testes, Adrenal gland, Brain

Animal Models for Lipoid Adrenal Hyperplasia or affiliated genes

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MGI Mouse Phenotypes related to Lipoid Adrenal Hyperplasia:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053799.0CYP11A1, CYP11B1, CYP11B2, NR5A1, POMC, STAR
2MP:00053898.1CYP11A1, CYP11B2, CYP17A1, NR5A1, POR, STAR

Publications for Lipoid Adrenal Hyperplasia

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Articles related to Lipoid Adrenal Hyperplasia:

(show top 50)    (show all 72)
idTitleAuthorsYear
1
Gonadal macrophage infiltration in congenital lipoid adrenal hyperplasia. (27190208)
2016
2
Clinical features and StAR gene mutations in children with congenital lipoid adrenal hyperplasia]. (26014698)
2015
3
Phenotypic variability in congenital lipoid adrenal hyperplasia. (24953586)
2014
4
p.R182C mutation in Korean twin with congenital lipoid adrenal hyperplasia. (24904850)
2013
5
Unique dominant negative mutation in the N-terminal mitochondrial targeting sequence of StAR, causing a variant form of congenital lipoid adrenal hyperplasia. (23175692)
2013
6
Characterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasia. (21647419)
2011
7
High allele frequency of the p.Q258X mutation and identification of a novel mis-splicing mutation in the STAR gene in Korean patients with congenital lipoid adrenal hyperplasia. (21846663)
2011
8
Partial defect in the cholesterol side-chain cleavage enzyme P450scc (CYP11A1) resembling nonclassic congenital lipoid adrenal hyperplasia. (21159840)
2011
9
Prenatal diagnosis of congenital lipoid adrenal hyperplasia (CLAH) by molecular genetic testing in Korean siblings. (22028173)
2011
10
Congenital lipoid adrenal hyperplasia: functional characterization of three novel mutations in the STAR gene. (20080861)
2010
11
A Novel Mutation of the Steroidogenic Acute Regulatory Protein (StAR) Gene in a Japanese Patient with Congenital Lipoid Adrenal Hyperplasia. (24790358)
2008
12
Role of a founder c.201_202delCT mutation and new phenotypic features of congenital lipoid adrenal hyperplasia in Palestinians. (17666473)
2007
13
Nonclassic congenital lipoid adrenal hyperplasia: a new disorder of the steroidogenic acute regulatory protein with very late presentation and normal male genitalia. (16968793)
2006
14
Ovarian insufficiency in congenital lipoid adrenal hyperplasia begins in infancy. (16607929)
2006
15
Imaging of congenital lipoid adrenal hyperplasia. (16875310)
2006
16
A novel mutation L260P of the steroidogenic acute regulatory protein gene in three unrelated patients of Swiss ancestry with congenital lipoid adrenal hyperplasia. (15985476)
2005
17
Adrenal and ovarian hormonogenesis in a teenage girl with congenital lipoid adrenal hyperplasia (CLAH). (15506684)
2004
18
Congenital lipoid adrenal hyperplasia caused by a novel splicing mutation in the gene for the steroidogenic acute regulatory protein. (14764819)
2004
19
Molecular genetic analysis of congenital lipoid adrenal hyperplasia]. (15347444)
2004
20
Family of two patients with congenital lipoid adrenal hyperplasia due to StAR mutation. (15666846)
2004
21
Molecular pathogenesis of lipoid adrenal hyperplasia and adrenal hypoplasia congenita. (12943739)
2003
22
Congenital lipoid adrenal hyperplasia caused by a frame-shift mutation in the steroidogenic acute regulatory protein gene. (17003020)
2003
23
Congenital lipoid adrenal hyperplasia. (10460667)
1999
24
A novel compound heterozygous mutation in the steroidogenic acute regulatory protein gene in a patient with congenital lipoid adrenal hyperplasia. (10566637)
1999
25
A novel frameshift mutation 840delA and a novel polymorphism D203A in the steroidogenic acute regulatory protein gene in a Japanese patient with congenital lipoid adrenal hyperplasia. (9452116)
1998
26
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia. (9326645)
1997
27
Analysis of the steroidogenic acute regulatory protein (StAR) gene in Japanese patients with congenital lipoid adrenal hyperplasia. (9097960)
1997
28
Homozygous Q258X mutation in the steroidogenic acute regulatory gene in a Japanese patient with congenital lipoid adrenal hyperplasia. (9279522)
1997
29
Spontaneous puberty in 46,XX subjects with congenital lipoid adrenal hyperplasia. Ovarian steroidogenesis is spared to some extent despite inactivating mutations in the steroidogenic acute regulatory protein (StAR) gene. (9077535)
1997
30
Congenital lipoid adrenal hyperplasia: the human gene knockout for the steroidogenic acute regulatory protein. (9460644)
1997
31
Spontaneous feminization in a 46,XX female patient with congenital lipoid adrenal hyperplasia due to a homozygous frameshift mutation in the steroidogenic acute regulatory protein. (9141542)
1997
32
New developments in congenital lipoid adrenal hyperplasia and steroidogenic acute regulatory protein. (9130927)
1997
33
P450scc deficiency (congenital lipoid adrenal hyperplasia): first reported case in Thailand and literature review. (8855637)
1996
34
The pathophysiology and genetics of congenital lipoid adrenal hyperplasia. (8948562)
1996
35
Prenatal diagnosis of congenital lipoid adrenal hyperplasia. (7829612)
1995
36
T-->A transversion 11 bp from a splice acceptor site in the human gene for steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia. (8634702)
1995
37
No mutation in cytochrome P450 side chain cleavage in a patient with congenital lipoid adrenal hyperplasia. (7962293)
1994
38
Prenatal diagnosis of congenital lipoid adrenal hyperplasia. (8469492)
1993
39
Congenital lipoid adrenal hyperplasia--genes for P450scc, side chain cleavage enzyme, are normal. (8481356)
1993
40
Normal genes for the cholesterol side chain cleavage enzyme, P450scc, in congenital lipoid adrenal hyperplasia. (1661294)
1991
41
The testicular lesion and sexual differentiation in congenital lipoid adrenal hyperplasia. (2501238)
1989
42
Computed tomography in the early detection of congenital lipoid adrenal hyperplasia. (3387163)
1988
43
Study of cholesterol side-chain cleavage (20,22 desmolase) deficiency causing congenital lipoid adrenal hyperplasia using bovine-sequence P450scc oligodeoxyribonucleotide probes. (2419119)
1986
44
Genetics and pathology of hereditary adrenal hyperplasia in the rabbit: a model for congenital lipoid adrenal hyperplasia. (731013)
1978
45
Cholesterol side-chain cleavage enzyme activity and cytochrome P-450 content in adrenal mitochondria of a patient with congenital lipoid adrenal hyperplasia (Prader disease). (872430)
1977
46
Effects of 25-hydroxycholesterol and aminoglutethimide in isolated rat adrenal cells. A model for congenital lipoid adrenal hyperplasia? (174962)
1976
47
Evidence for deficient 20 -cholesterol-hydroxylase activity in adrenal tissue of a patient with lipoid adrenal hyperplasia. (4678198)
1972
48
Experimental congenital lipoid adrenal hyperplasia: prevention of anatomic defects produced by aminoglutethimide. (5529931)
1970
49
Production of congenital lipoid adrenal hyperplasia in rats and inhibition of cholesterol side-chain cleavage. (5427271)
1970
50
LIPOID ADRENAL HYPERPLASIA. (14225142)
1964

Variations for Lipoid Adrenal Hyperplasia

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UniProtKB/Swiss-Prot genetic disease variations for Lipoid Adrenal Hyperplasia:

69
id Symbol AA change Variation ID SNP ID
1STARp.Arg182LeuVAR_005627rs104894086
2STARp.Glu169GlyVAR_014236
3STARp.Glu169LysVAR_014237rs747169620
4STARp.Arg217ThrVAR_014238rs28938471
5STARp.Ala218ValVAR_014239rs137852690
6STARp.Met225ThrVAR_014240
7STARp.Leu275ProVAR_014242rs762245736

Clinvar genetic disease variations for Lipoid Adrenal Hyperplasia:

5 (show all 19)
id Gene Variation Type Significance SNP ID Assembly Location
1CYP11B1NM_000497.3(CYP11B1): c.124C> T (p.Pro42Ser)SNVPathogenicrs104894069GRCh37Chr 8, 143961106: 143961106
2CYP11B1NM_000497.3(CYP11B1): c.281C> T (p.Pro94Leu)SNVPathogenicrs104894070GRCh37Chr 8, 143960562: 143960562
3CYP17A1NM_000102.3(CYP17A1): c.1435_1438dupATCC (p.Pro480Hisfs)duplicationLikely pathogenic, Pathogenicrs556794126GRCh38Chr 10, 102830791: 102830794
4STARNM_000349.2(STAR): c.577C> T (p.Arg193Ter)SNVPathogenicrs387907235GRCh37Chr 8, 38003554: 38003554
5STARNM_000349.2(STAR): c.135delT (p.Ser46Alafs)deletionLikely pathogenicrs193922393GRCh37Chr 8, 38006202: 38006202
6STARNM_000349.2: c.629_630delCTdeletionLikely pathogenicChr na, -1: -1
7STARSTAR, IVS4AS, T-A, -11SNVPathogenicChr na, -1: -1
8STARNM_000349.2(STAR): c.772C> T (p.Gln258Ter)SNVPathogenicrs104894085GRCh37Chr 8, 38001877: 38001877
9STARNM_000349.2(STAR): c.545G> T (p.Arg182Leu)SNVPathogenicrs104894086GRCh37Chr 8, 38003586: 38003586
10STARSTAR, 1-BP DEL, 261TdeletionPathogenicChr na, -1: -1
11STARSTAR, IVS2, 1-BP INS, T, +3insertionPathogenicChr na, -1: -1
12STARNM_000349.2(STAR): c.749G> A (p.Trp250Ter)SNVPathogenicrs104894087GRCh37Chr 8, 38001900: 38001900
13STARNM_000349.2(STAR): c.650G> C (p.Arg217Thr)SNVPathogenicrs137852689GRCh37Chr 8, 38003481: 38003481
14STARNM_000349.2(STAR): c.653C> T (p.Ala218Val)SNVPathogenicrs137852690GRCh37Chr 8, 38002831: 38002831
15STARSTAR, IVS1, G-T, +1SNVPathogenicChr na, -1: -1
16STARNM_000349.2(STAR): c.545G> A (p.Arg182His)SNVPathogenicrs104894086GRCh37Chr 8, 38003586: 38003586
17STARNM_000349.2(STAR): c.559G> A (p.Val187Met)SNVPathogenicrs104894089GRCh37Chr 8, 38003572: 38003572
18STARNM_000349.2(STAR): c.562C> T (p.Arg188Cys)SNVPathogenicrs104894090GRCh37Chr 8, 38003569: 38003569
19STARSTAR, 2-BP DEL, 201CTdeletionPathogenicChr na, -1: -1

Copy number variations for Lipoid Adrenal Hyperplasia from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
121051163040000036600000DuplicationCYP21A2Congenital adrenal hyperplasia
221266964050000046200000Copy numberCongenital adrenal hyperplasia

Expression for genes affiliated with Lipoid Adrenal Hyperplasia

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Search GEO for disease gene expression data for Lipoid Adrenal Hyperplasia.

Pathways for genes affiliated with Lipoid Adrenal Hyperplasia

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GO Terms for genes affiliated with Lipoid Adrenal Hyperplasia

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Cellular components related to Lipoid Adrenal Hyperplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1smooth endoplasmic reticulum membraneGO:00308689.8HSD3B1, HSD3B2
2mitochondrial intermembrane spaceGO:00057589.2HSD3B1, HSD3B2, STAR
3mitochondrial inner membraneGO:00057438.0CYP11A1, CYP11B1, CYP11B2, HSD3B1, HSD3B2
4endoplasmic reticulum membraneGO:00057898.0CYP17A1, CYP21A2, HSD3B1, HSD3B2, POR
5mitochondrionGO:00057397.9CYP11A1, CYP11B1, CYP11B2, CYP17A1, POR, STAR

Biological processes related to Lipoid Adrenal Hyperplasia according to GeneCards Suite gene sharing:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1response to fungicideGO:006099210.6CYP17A1, STAR
2phenol-containing compound metabolic processGO:001895810.6CYP17A1, STAR
3phthalate metabolic processGO:001896310.5CYP17A1, STAR
4response to steroid hormoneGO:004854510.5CYP17A1, STAR
5response to insecticideGO:001708510.5CYP17A1, STAR
6cellular response to antibioticGO:007123610.5CYP17A1, STAR
7biphenyl metabolic processGO:001887910.5CYP17A1, STAR
8cellular response to follicle-stimulating hormone stimulusGO:007137210.4POR, STAR
9positive regulation of steroid hormone biosynthetic processGO:009003110.4CYP17A1, POR
10response to herbicideGO:000963510.4CYP17A1, STAR
11dibenzo-p-dioxin metabolic processGO:001889410.3CYP17A1, STAR
12regulation of steroid biosynthetic processGO:005081010.2NR5A1, STAR
13adrenal gland developmentGO:003032510.1CYP17A1, NR5A1
14cortisol biosynthetic processGO:003465110.1CYP11B1, CYP11B2
15aldosterone biosynthetic processGO:003234210.1CYP11B1, CYP11B2
16cellular response to potassium ionGO:003586510.1CYP11B1, CYP11B2
17cellular response to hormone stimulusGO:003287010.1CYP11B1, CYP11B2
18steroid metabolic processGO:000820210.1CYP17A1, CYP21A2
19cellular response to gonadotropin stimulusGO:007137110.0CYP17A1, POR, STAR
20estrogen biosynthetic processGO:00067039.9HSD3B1, STAR
21secondary metabolite biosynthetic processGO:00445509.8CYP11A1, CYP11B1, CYP11B2
22C21-steroid hormone biosynthetic processGO:00067009.6CYP11A1, CYP11B1, CYP11B2, STAR
23cholesterol metabolic processGO:00082039.4CYP11A1, CYP11B1, CYP11B2, STAR
24androgen biosynthetic processGO:00067029.3CYP17A1, HSD3B1, HSD3B2
25cellular response to peptide hormone stimulusGO:00713759.3CYP11A1, CYP11B1, CYP11B2, POR
26sterol metabolic processGO:00161258.9CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP21A2
27mineralocorticoid biosynthetic processGO:00067058.7CYP11B2, CYP21A2, HSD3B1, HSD3B2
28steroid biosynthetic processGO:00066948.5CYP17A1, CYP21A2, HSD3B1, HSD3B2, STAR
29glucocorticoid biosynthetic processGO:00067048.4CYP11A1, CYP11B1, CYP17A1, CYP21A2, HSD3B1, HSD3B2
30oxidation-reduction processGO:00551146.8CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP21A2, HSD3B1

Molecular functions related to Lipoid Adrenal Hyperplasia according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1corticosterone 18-monooxygenase activityGO:004778310.1CYP11B1, CYP11B2
2steroid 11-beta-monooxygenase activityGO:000450710.1CYP11B1, CYP11B2
3oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygenGO:00167099.8CYP11A1, CYP11B1, CYP11B2
4steroid delta-isomerase activityGO:00047699.7HSD3B1, HSD3B2
53-beta-hydroxy-delta5-steroid dehydrogenase activityGO:00038549.7HSD3B1, HSD3B2
6steroid hydroxylase activityGO:00083959.7CYP11B2, CYP21A2
7heme bindingGO:00200378.6CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP21A2
8iron ion bindingGO:00055068.3CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP21A2

Sources for Lipoid Adrenal Hyperplasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet