MCID: LPM004
MIFTS: 60

Lipoma malady

Categories: Genetic diseases, Rare diseases, Skin diseases, Cancer diseases

Aliases & Classifications for Lipoma

Aliases & Descriptions for Lipoma:

Name: Lipoma 54 12 29 52 14 69
Multiple Lipomatosis 12 50 29
Familial Multiple Lipomatosis 50 56
Benign Lipomatous Tumor 12 69
Lipomatosis, Multiple 54 69
Lipomatous Neoplasm 12 69
Benign Tumor of Adipose Tissue 12
Lipomatosis, Familial Multiple 12
Neoplasms, Adipose Tissue 42
Tumor of Adipose Tissue 12
Lipomatous Tumor 12

Characteristics:

HPO:

32
lipoma:
Inheritance autosomal dominant inheritance


Classifications:

Orphanet: 56  
Rare skin diseases


Summaries for Lipoma

NIH Rare Diseases : 50 familial multiple lipomatosis (fml) is a rare condition that is characterized by multiple lipomas on the trunk and extremities. as the name suggests, fml is diagnosed when multiple lipomatosis occurs in more than one family member, often over several generations. the lipomas associated with fml are usually painless, but may impact quality of life as they can be numerous and large. although the condition appears to be passed down through families in an autosomal dominant manner, the underlying genetic cause is currently unknown. treatment is based on the signs and symptoms present in each person. surgical excision may be necessary if the tumors interfere with movement and/or daily life. last updated: 3/31/2016

MalaCards based summary : Lipoma, also known as multiple lipomatosis, is related to pleural lipoma and pleomorphic lipoma, and has symptoms including seizures, cerebral calcification and bowing of the long bones. An important gene associated with Lipoma is LPP (LIM Domain Containing Preferred Translocation Partner In Lipoma), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Oncogene Induced Senescence. The drugs Pioglitazone and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include colon, breast and spinal cord.

Disease Ontology : 12 A cell type benign neoplasm that is composed of lipocytes.

OMIM : 54 Familial multiple lipomatosis is a rare autosomal dominant disorder characterized by numerous encapsulated lipomas on... (151900) more...

Wikipedia : 71 A lipoma is a benign tumor composed of adipose tissue (body fat). It is the most common benign form of... more...

Related Diseases for Lipoma

Diseases related to Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 310)
id Related Disease Score Top Affiliating Genes
1 pleural lipoma 32.9 CDK4 HMGA2 MDM2
2 pleomorphic lipoma 12.2
3 spindle cell lipoma 12.1
4 chondroid lipoma 12.1
5 spinal cord lipoma 12.1
6 palpebral coloboma-lipoma syndrome 12.0
7 infiltrating lipoma 11.9
8 endobronchial lipoma 11.9
9 corpus callosum lipoma 11.9
10 breast lipoma 11.9
11 chest wall lipoma 11.9
12 axillary lipoma 11.9
13 lumbosacral lipoma 11.9
14 esophageal lipoma 11.8
15 internal auditory canal lipoma 11.8
16 liver lipoma 11.8
17 tendon sheath lipoma 11.8
18 lipoma of spermatic cord 11.8
19 lipoma of the rectum 11.8
20 paratesticular lipoma 11.8
21 skin lipoma 11.8
22 lipoma of colon 11.7
23 kidney lipoma 11.7
24 cerebral hemisphere lipoma 11.7
25 external auditory meatus lipoma 11.7
26 large intestine lipoma 11.7
27 extrahepatic bile duct lipoma 11.7
28 gallbladder lipoma 11.7
29 classic type lipoma 11.7
30 thymus lipoma 11.7
31 epicardium lipoma 11.7
32 heart lipoma 11.7
33 bannayan-riley-ruvalcaba syndrome 11.7
34 cleft lip/palate-deafness-sacral lipoma syndrome 11.6
35 cleft, median, of upper lip with polyps of facial skin and nasal mucosa 11.4
36 lipomatosis 11.3
37 angiolipoma 11.3
38 atypical lipomatous tumor 11.2
39 adiposis dolorosa 11.1
40 encephalocraniocutaneous lipomatosis 11.0
41 birt-hogg-dube syndrome 11.0
42 multiple endocrine neoplasia 1 11.0
43 lipomatosis, multiple symmetric 11.0
44 legius syndrome 10.9
45 hemihyperplasia-multiple lipomatosis syndrome 10.7
46 adenomatoid tumor 10.7
47 frontofacionasal dysplasia 10.7
48 proteus syndrome, somatic 10.7
49 adenomatous polyposis coli 10.7
50 pulmonary hypertension, chronic thromboembolic, without deep vein thrombosis 10.3 LHFPL3 LHFPL5

Graphical network of the top 20 diseases related to Lipoma:



Diseases related to Lipoma

Symptoms & Phenotypes for Lipoma

Symptoms by clinical synopsis from OMIM:

151900

Clinical features from OMIM:

151900

Human phenotypes related to Lipoma:

56 32 (show all 24)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 seizures 56 32 Occasional (29-5%) HP:0001250
2 cerebral calcification 56 32 Occasional (29-5%) HP:0002514
3 bowing of the long bones 56 32 Occasional (29-5%) HP:0006487
4 delayed speech and language development 56 32 Occasional (29-5%) HP:0000750
5 peripheral neuropathy 56 32 Frequent (79-30%) HP:0009830
6 ventriculomegaly 56 32 Occasional (29-5%) HP:0002119
7 hyperlipidemia 56 32 Frequent (79-30%) HP:0003077
8 abnormality of the tricuspid valve 56 32 Occasional (29-5%) HP:0001702
9 accelerated skeletal maturation 56 32 Occasional (29-5%) HP:0005616
10 increased adipose tissue 56 32 Very frequent (99-80%) HP:0009126
11 hypoplasia of the corpus callosum 56 32 Occasional (29-5%) HP:0002079
12 insulin resistance 56 32 Very frequent (99-80%) HP:0000855
13 coloboma 56 32 Occasional (29-5%) HP:0000589
14 overgrowth 56 32 Occasional (29-5%) HP:0001548
15 medulloblastoma 56 32 Occasional (29-5%) HP:0002885
16 functional intestinal obstruction 56 32 Frequent (79-30%) HP:0005249
17 premature eruption of permanent teeth 56 32 Occasional (29-5%) HP:0006337
18 lipodystrophy 56 32 Very frequent (99-80%) HP:0009125
19 chorioretinitis 56 32 Occasional (29-5%) HP:0012424
20 arachnoid cyst 56 32 Occasional (29-5%) HP:0100702
21 macrocephaly 56 Occasional (29-5%)
22 multiple lipomas 32 HP:0001012
23 keratocystic odontogenic tumor 56 Occasional (29-5%)
24 odontogenic keratocysts of the jaw 32 HP:0010603

Drugs & Therapeutics for Lipoma

Drugs for Lipoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 326)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pioglitazone Approved, Investigational Phase 4,Phase 2 111025-46-8 4829
2
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
3
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
4
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
5
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
6
Methyltestosterone Approved Phase 4,Phase 2 58-18-4 6010
7
Testosterone Approved, Investigational Phase 4,Phase 2 58-22-0 6013
8
Hydroxocobalamin Approved Phase 4 13422-51-0 11953898 5460373 44475014
9
Metformin Approved Phase 4,Phase 3,Phase 2 657-24-9 14219 4091
10
Anastrozole Approved, Investigational Phase 4 120511-73-1 2187
11
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 59-30-3 6037
12
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 2 59-67-6 938
13
Nicotinamide Approved, Nutraceutical Phase 4,Phase 2 98-92-0 936
14
Cyanocobalamin Approved, Nutraceutical Phase 4 68-19-9 44176380
15 Antimetabolites Phase 4,Phase 2,Phase 1
16 Hypoglycemic Agents Phase 4,Phase 3,Phase 2,Phase 1
17 Hypolipidemic Agents Phase 4
18 Lipid Regulating Agents Phase 4
19 Micronutrients Phase 4,Phase 2,Phase 3
20 Nicotinic Acids Phase 4,Phase 2
21 Trace Elements Phase 4,Phase 2,Phase 3
22 Vasodilator Agents Phase 4,Phase 2
23 Vitamin B Complex Phase 4,Phase 2
24 Vitamins Phase 4,Phase 2
25 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
26 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1
27 Antifungal Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
29 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
30 insulin Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
31 Insulin, Globin Zinc Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
32 Antihypertensive Agents Phase 4,Phase 3,Phase 2
33 2,4-thiazolidinedione Phase 4
34 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
35 Matrix Metalloproteinase Inhibitors Phase 4
36
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
37 TIMP1 protein, human Phase 4
38 TIMP3 protein, human Phase 4
39 Tissue Inhibitor of Metalloproteinase-1 Phase 4
40 Tissue Inhibitor of Metalloproteinase-3 Phase 4
41 Tissue Inhibitor of Metalloproteinases Phase 4
42
Angiotensin II Phase 4,Phase 3 68521-88-0, 11128-99-7 65143 172198
43 Angiotensin II Type 1 Receptor Blockers Phase 4,Phase 3
44 Angiotensin Receptor Antagonists Phase 4,Phase 3
45 Angiotensinogen Phase 4,Phase 3
46 Anti-Inflammatory Agents Phase 4,Phase 1,Phase 2,Early Phase 1
47 Anabolic Agents Phase 4,Phase 3,Phase 2
48 Androgens Phase 4,Phase 3,Phase 2
49 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 1,Phase 2
50 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 347)
id Name Status NCT ID Phase
1 Pioglitazone Vs Placebo in Combination With Niacin Extended Release on Low HDL Unknown status NCT00300365 Phase 4
2 Rapamycin In Angiomyolipomas In Patients With Tuberous Sclerosis Completed NCT01217125 Phase 4
3 Effect of Pioglitazone on TIMP-3 and TACE in Type 2 Diabetes Completed NCT01223196 Phase 4
4 Anti-Inflammatory Actions of Valsartan in Patients With Type 2 Diabetes Mellitus Completed NCT00982358 Phase 4
5 Epicardial Adipose Tissue Thickness in Polycystic Ovary Syndrome (PCOS) Completed NCT01258946 Phase 4
6 Testosterone for Men With Insulin Treated Type 2 Diabetes Completed NCT00349362 Phase 4
7 Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance Completed NCT00667498 Phase 4
8 Sitagliptin and Brown Adipose Tissue Recruiting NCT02294084 Phase 4
9 Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot) Recruiting NCT02959853 Phase 4
10 Fish Oils and Adipose Inflammation Reduction Recruiting NCT02010359 Phase 4
11 Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS) Recruiting NCT02500147 Phase 4
12 Feasibility and Yield of a New 20 G ProCore Needle With Coiled Sheath in the Gastrointestinal Subepithelial Tumors Enrolling by invitation NCT02884154 Phase 4
13 Ultra-sounded Guided Regional Blockade for Lipoma Excision Not yet recruiting NCT02753361 Phase 4
14 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Unknown status NCT00346164 Phase 3
15 Effect on the Nutritional and Inflammatory Status of Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)- Containing Supplement in Patients With Advanced Lung Cancer Unknown status NCT01048970 Phase 2, Phase 3
16 Proton Magnetic Resonance Spectroscopy (1H MRS) in Evaluating the Bone Marrow, Muscle and Adipose Tissue on Normal and Human Immunodeficiency Virus Infected Subjects Unknown status NCT00172315 Phase 3
17 Breast Cancer and Exercise Trial in Alberta Completed NCT01435005 Phase 3
18 A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma Completed NCT01343277 Phase 3
19 Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer Completed NCT00070148 Phase 3
20 An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation Completed NCT00132704 Phase 3
21 Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) Completed NCT00790400 Phase 3
22 Effect of Exercise on Biomarkers of Colon Cancer Risk Completed NCT00668161 Phase 2, Phase 3
23 Lifestyle, Exercise and Nutrition Study 1 Completed NCT02109068 Phase 3
24 Effect of Exercise on Sex Hormones in Postmenopausal Women Completed NCT00668174 Phase 2, Phase 3
25 Effect of DHA on Lipid and Carbohydrate Metabolism Alterations and Body Fat Distribution in HIV Patients Under HAART. Completed NCT02005900 Phase 3
26 Effect of the LIVESTRONG at the YMCA Exercise Program on Cancer Related Outcomes in Cancer Survivors Completed NCT02112149 Phase 3
27 Physical Activity and Breast Cancer Risk in Postmenopausal Women:the SHAPE Study Completed NCT00359060 Phase 3
28 PEACH Trial: Prescribed Exercise After Chemotherapy Completed NCT01030887 Phase 3
29 A Home-based Physical Activity Intervention in Breast Cancer Survivors Completed NCT02408107 Phase 3
30 Effectiveness of Nutritional Counselling and "Improved Atta" Supplementation in Cachexic Adult Indian Cancer Patients Completed NCT02561143 Phase 2, Phase 3
31 Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial Completed NCT00147264 Phase 3
32 Growth Hormone Treatment in Men With High Risk of Developing Type 2 Diabetes Mellitus Completed NCT00781547 Phase 3
33 Omega 3 Fish Oil Supplements vs. Placebo for Patients With Non-alcoholic Steatohepatitis (NASH) Completed NCT00681408 Phase 2, Phase 3
34 Effect of Weight & Insulin Sensitivity on Reproductive Function in PCOS: Studies in Skeletal Muscle & Adipose Completed NCT01775176 Phase 3
35 BMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose Truvada Completed NCT00272779 Phase 3
36 Study Comparing Lopinavir/Ritonavir (LPV/r) + Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) With a Nucleoside Sparing Regimen Consisting of Lopinavir/Ritonavir + Raltegravir (RAL) Completed NCT00711009 Phase 3
37 Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy Completed NCT00283816 Phase 3
38 Selinexor in Advanced Liposarcoma Recruiting NCT02606461 Phase 2, Phase 3
39 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3
40 Efficacy of EPA-enriched Supplement in Malnourished Head and Neck Cancer Patients Undergone Surgery Recruiting NCT02321631 Phase 3
41 Laser Mucite ORL : Effectiveness of Laser Therapy for Mucositis Induced by a Radio-chemotherapy in Head and Neck Cancer Recruiting NCT01772706 Phase 3
42 Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients Recruiting NCT02802540 Phase 2, Phase 3
43 Adipose Tissue Transfer for Moderate Breast Cancer Conservative Treatment Sequella Active, not recruiting NCT01035268 Phase 3
44 A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma Active, not recruiting NCT01692678 Phase 3
45 Pre-pectoral Breast Reconstruction PART 2 Not yet recruiting NCT02831426 Phase 3
46 Sirolimus in Treating Patients With Angiomyolipoma of the Kidney Unknown status NCT00126672 Phase 2
47 Brostallicin Clinical Trial for Myxoid Liposarcoma Unknown status NCT00633165 Phase 2
48 Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers Unknown status NCT02104011 Phase 2
49 L-leucine in Diamond Blackfan Anemia Patients Unknown status NCT02386267 Phase 2
50 A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma Completed NCT01613313 Phase 2

Search NIH Clinical Center for Lipoma

Cochrane evidence based reviews: neoplasms, adipose tissue

Genetic Tests for Lipoma

Genetic tests related to Lipoma:

id Genetic test Affiliating Genes
1 Lipoma 29
2 Lipomatosis, Multiple 29

Anatomical Context for Lipoma

MalaCards organs/tissues related to Lipoma:

39
Colon, Breast, Spinal Cord, Tongue, Bone, Skin, Pancreas

Publications for Lipoma

Articles related to Lipoma:

(show top 50) (show all 1216)
id Title Authors Year
1
The many faces of cardiac lipoma-an egg in the heart! ( 28379336 )
2017
2
Lipoma in the Face Associated With Maxillofacial Trauma. ( 27922958 )
2017
3
Parosteal ossifying lipoma of the clavicle: A case report. ( 28451424 )
2017
4
Laryngeal lipoma: a rare cause of dysphonia. ( 28450988 )
2017
5
Cytogenetic Analysis of a Pseudoangiomatous Pleomorphic/Spindle Cell Lipoma. ( 28476785 )
2017
6
Frontal and caudal maxillary sinus lipoma in a horse. ( 28487595 )
2017
7
Transabdominal wall lipoma. ( 28389501 )
2017
8
Giant lipoma extending into two thigh canals: A case report. ( 28446375 )
2017
9
Invasive Cardiac Lipoma: a case report and review of literature. ( 28088193 )
2017
10
Intraosseous Lipoma of the Mandibula: A Case Report and Review of the Literature. ( 28401200 )
2017
11
Intra-abdominal necrotic lipoma diagnosed as a paraprostatic cyst by CT scan. ( 28385006 )
2017
12
Extra-Oral Excision of a Buccal Fat Pad Lipoma. ( 28468196 )
2017
13
Laparoscopic resection of a sigmoid colon lipoma in a young female patient: A case report and review of the literature. ( 28454251 )
2017
14
Cauda equina syndrome caused by filum terminale lipoma: magnetic resonance imaging features and surgical treatment. ( 28444101 )
2017
15
Limitations and pitfalls in prenatal diagnosis of pericallosal curvilinear lipoma based on a specific imaging pattern. ( 28067000 )
2017
16
Neck and Occipital Pain Caused by Deep Cervical Intramuscular Lipoma: A Surgical Case. ( 28502967 )
2017
17
A rare cause of acute gastrointestinal hemorrhage: ileal lipoma Case report. ( 28447964 )
2017
18
Lipoma in the femoral triangle. ( 28491332 )
2017
19
Fat Free Pleomorphic Lipoma of Oral Cavity: A Rare Entity. ( 28511518 )
2017
20
The Case of Huge Pure Lipoma of the Spermatic Cord Misdiagnosed as Inguinal Hernia. ( 28417076 )
2017
21
Cytohistological Features of Spindle Cell Lipoma- A Case Report with Differential Diagnosis. ( 28384874 )
2017
22
Spindle Cell Lipoma in Dogs. ( 28494701 )
2017
23
The robotic approach for enucleation of a giant esophageal lipoma. ( 28005192 )
2016
24
PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/Ba8^ subunit to regulate cell adhesion and migration. ( 26945059 )
2016
25
Molecular characterization of the t(4;12)(q27~28;q14~15) chromosomal rearrangement in lipoma. ( 27588119 )
2016
26
Posterior interosseous nerve discontinuity due to compression by lipoma: report of 2 cases. ( 27177178 )
2016
27
Transverse Colon Submucosal Lipoma Presenting With Colocolic Intussusception. ( 27144190 )
2016
28
IMAGING DIAGNOSIS-CONCENTRIC PERIRADICULAR LIPOMA CAUSING LUMBAR NERVE ROOT COMPRESSION IN A DOG. ( 27147585 )
2016
29
Giant ileocolic intussusception in an adult induced by a double ileal lipoma: a case report with pathologic correlation. ( 27594938 )
2016
30
Pseudoangiomatous Spindle Cell Lipoma: a distinct subtype of spindle cell lipoma. ( 27982506 )
2016
31
Dermal plexiform spindle cell lipoma. ( 27833986 )
2016
32
Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma. ( 26913848 )
2016
33
Laparoscopic excision of a lipoma of parietal peritoneum. ( 27073320 )
2016
34
S-100 protein expressing spindle cells in spindle cell lipoma: a diagnostic pitfall. ( 27444171 )
2016
35
Arthroscopic Synovectomy in Bilateral Lipoma Arborescens. ( 28507957 )
2016
36
Combined Median and Ulnar Nerve Compression Neuropathy due to Lipoma at the Wrist. ( 27616831 )
2016
37
Lipoma of the quadrigeminal plate cistern. ( 28050076 )
2016
38
Post-traumatic Lipoma of the Parotid gland. ( 27106616 )
2016
39
Spinal lipoma as a dysembryogenetic anomaly: Four unusual cases of ectopic iliac rib within the spinal lipoma. ( 27087621 )
2016
40
Pseudoangiomatous variant of spindle cell lipoma: Report of a rare case. ( 27510682 )
2016
41
Gingival lipoma. ( 27657162 )
2016
42
Lipoma Arborescens: a rare cause of recurrent synovial hydrathrosis at paediatric age. ( 27115114 )
2016
43
Spinal lipoma of the filum terminale: review of 174 consecutive patients. ( 27060067 )
2016
44
Lipoma-Like Bronchogenic Cyst in the Right Chest Sidewall: A Case Report and Literature Review. ( 27263614 )
2016
45
Lipoma of the Tympanic Membrane. ( 27617817 )
2016
46
Lipoma of the Palate: An Uncommon Finding. ( 28077968 )
2016
47
Low-Fat Plexiform Spindle Cell Lipoma With Prominent Myxoid Stroma: An Unusual Oral Presentation and Immunohistochemical Analysis. ( 28045832 )
2016
48
Endoscopic Submucosal Dissection of a Giant Esophageal Lipoma. ( 27924084 )
2016
49
Lipoma-induced colonic intussusception in mobile cecum syndrome. ( 28007681 )
2016
50
Spindle Cell Lipoma in an End-Stage Renal Allograft: Case Report. ( 27932168 )
2016

Variations for Lipoma

Cosmic variations for Lipoma:

9
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM775 PIK3CA soft tissue,fat,Overgrowth syndrome,lipoma c.3140A>G p.H1047R 7

Copy number variations for Lipoma from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 173076 3 189413414 190080135 Translate LPP Lipoma

Expression for Lipoma

Search GEO for disease gene expression data for Lipoma.

Pathways for Lipoma

Pathways related to Lipoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.05 HMGA2 MDM2 MEN1
2 10.46 CDK4 MDM2

GO Terms for Lipoma

Cellular components related to Lipoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chromatin GO:0000785 9.13 CDK4 HMGA2 MEN1
2 senescence-associated heterochromatin focus GO:0035985 8.62 HMGA1 HMGA2

Biological processes related to Lipoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 adipose tissue development GO:0060612 9.37 CDK4 HMGA2
2 negative regulation of cell cycle arrest GO:0071157 9.32 CDK4 MDM2
3 cellular response to peptide hormone stimulus GO:0071375 9.26 MDM2 MEN1
4 positive regulation of cellular senescence GO:2000774 9.16 HMGA1 HMGA2
5 senescence-associated heterochromatin focus assembly GO:0035986 8.96 HMGA1 HMGA2
6 oncogene-induced cell senescence GO:0090402 8.62 HMGA1 HMGA2

Molecular functions related to Lipoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 9.16 HMGA1 HMGA2
2 peroxisome proliferator activated receptor binding GO:0042975 8.96 HMGA1 MDM2
3 AT DNA binding GO:0003680 8.62 HMGA1 HMGA2

Sources for Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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