LPL DEFICIENCY
MCID: LPP001
MIFTS: 63

Lipoprotein Lipase Deficiency (LPL DEFICIENCY) malady

Categories: Genetic diseases, Metabolic diseases, Endocrine diseases, Rare diseases

Aliases & Classifications for Lipoprotein Lipase Deficiency

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Aliases & Descriptions for Lipoprotein Lipase Deficiency:

Name: Lipoprotein Lipase Deficiency 52 70 12
Hyperlipoproteinemia Type I 27 68
Familial Chylomicronemia 70 27
Lpl Deficiency 54 70
Familial Lipoprotein Lipase Deficiency 54
 
Hyperlipoproteinemia Type 1a 70
Hyperlipoproteinemia, Type I 52
Hyperlipoproteinemia Type Ia 70
Lipoprotein Lipase 12

Characteristics:

HPO:

64
lipoprotein lipase deficiency:
Inheritance: autosomal recessive inheritance

Classifications:



External Ids:

OMIM52 238600
Orphanet54 ORPHA309015
ICD10 via Orphanet31 E78.3

Summaries for Lipoprotein Lipase Deficiency

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UniProtKB/Swiss-Prot:70 Lipoprotein lipase deficiency: Recessive disorder usually manifesting in childhood. On a normal diet, patients often present with abdominal pain, hepatosplenomegaly, lipemia retinalis, eruptive xanthomata, and massive hypertriglyceridemia, sometimes complicated with acute pancreatitis.

MalaCards based summary: Lipoprotein Lipase Deficiency, also known as hyperlipoproteinemia type i, is related to hypertriglyceridemia and familial lipoprotein lipase deficiency, and has symptoms including lipemia retinalis, jaundice and eruptive xanthomas. An important gene associated with Lipoprotein Lipase Deficiency is LPL (Lipoprotein Lipase), and among its related pathways are Fat digestion and absorption and Binding and Uptake of Ligands by Scavenger Receptors. Affiliated tissues include endothelial, heart and monocytes, and related mouse phenotypes are Increased LDL uptake and Decreased free cholesterol.

Wikipedia:71 Lipoprotein lipase deficiency (also known as \"familial chylomicronemia syndrome\", \"chylomicronemia\",... more...

Description from OMIM:52 238600

Related Diseases for Lipoprotein Lipase Deficiency

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Diseases related to Lipoprotein Lipase Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1hypertriglyceridemia29.4APOA1, APOB, APOC3, APOE, CETP, LCAT
2familial lipoprotein lipase deficiency12.7
3lipase deficiency, combined11.2
4alport syndrome and thin basement membrane nephropathy10.3APOE, LPL
5pancreatitis10.3
6arena syndrome10.3APOA1, LCAT
7zap-70 deficiency10.3APOB, APOE
8keratoconus 410.3APOB, APOE
9abducens nerve neoplasm10.2LPL, PNLIP
10lipoprotein glomerulopathy10.2APOE, LCAT
11severe intellectual disability-progressive postnatal microcephaly- midline stereotypic hand movements syndrome10.2APOB, APOE, LPL
12tyrosinemia, type ii10.2APOA1, LCAT
13atopic dermatitis 410.2APOC3, LPA
14dentinogenesis imperfecta type 210.2APOB, APOE, LCAT
15familial progressive cardiac conduction defect10.2APOA1, APOE, LCAT
16hypercholesterolemia, due to ligand-defective apo b10.2APOB, APOE, LCAT
17myxofibrosarcoma10.2APOE, LPL
18anaplastic ganglioglioma10.1APOA1, LCAT, LPA
19pars planitis10.1APOA1, APOE
20spinocerebellar ataxia 2010.1APOA1, APOB, LPA
21c1s deficiency10.1APOE, INS, LPL
22cataract 20, multiple types10.1APOB, INS, LPL
23cetp-related hyperalphalipoproteinemia10.1APOB, APOE, INS
24congenital chloride diarrhea10.1APOA1, APOB, LPA
25craniodiaphyseal dysplasia10.1APOA1, APOB, C3
26hyperchlorhidrosis, isolated10.1APOA1, APOE, LPL, PNLIP
27posterior uveal melanoma10.1APOA1, APOB, INS
28albinism, oculocutaneous, type v10.1APOA1, APOB, APOE, LPA
29alzheimer disease 19, late onset10.0APOB, APOE, LCAT, LPA
30optic nerve neoplasm10.0APOA1, APOB, APOE, LPA
31fetal warfarin syndrome10.0APOA1, APOB, INS, LCAT
32primary pigmented nodular adrenocortical disease10.0APOA1, APOB, APOE, INS
33body dysmorphic disorder10.0APOA1, APOB, INS
34iron metabolism disease10.0APOE, PLTP
35joint disorders10.0APOA1, APOB, APOE, INS, LPL
36muscular dystrophy, limb-girdle, type ic10.0BTD, LPL
37thymus adenosquamous carcinoma9.9APOA1, C3, LCAT
38asphyxia neonatorum9.9APOE, LPA, LPL, PON1
39dyserythropoietic anemia, congenital, type ii9.9APOA1, APOC3, APOE, LCAT, LPA
40camptodactyly-arthropathy-coxa vara-pericarditis syndrome9.9APOB, APOE, C3, CETP
41atherosclerosis9.9
42hepatitis9.9
43endotheliitis9.9
44mannosidosis, beta9.9APOA1, APOB, APOE, CETP, LCAT, LPL
45bird fancier's lung9.9APOA1, APOB, APOE, LCAT, LPA, LPL
46skin squamous cell carcinoma9.8APOA1, APOB, APOE, CETP, LPA, LPL
47bleeding disorder, east texas type9.8APOA1, APOB, APOC3, APOE, INS, LPL
48gait apraxia9.8APOA1, APOB, APOE, CETP, PON1
49stone in bladder diverticulum9.8APOA1, APOB, APOE, CETP, LCAT, LPA
50cervix small cell carcinoma9.8APOA1, APOB, APOE, INS, PON1

Comorbidity relations with Lipoprotein Lipase Deficiency via Phenotypic Disease Network (PDN):


Hypertension, EssentialIschemic Heart Disease
Intermediate Coronary Syndrome

Graphical network of the top 20 diseases related to Lipoprotein Lipase Deficiency:



Diseases related to lipoprotein lipase deficiency

Symptoms & Phenotypes for Lipoprotein Lipase Deficiency

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Symptoms by clinical synopsis from OMIM:

238600

Clinical features from OMIM:

238600

Human phenotypes related to Lipoprotein Lipase Deficiency:

 64 (show all 24)
id Description HPO Frequency HPO Source Accession
1 lipemia retinalis64 HP:0000660
2 jaundice64 HP:0000952
3 eruptive xanthomas64 HP:0001013
4 hepatosplenomegaly64 HP:0001433
5 pancreatitis64 HP:0001733
6 splenomegaly64 HP:0001744
7 vomiting64 HP:0002013
8 nausea64 HP:0002018
9 episodic abdominal pain64 HP:0002574
10 hyperlipidemia64 HP:0003077
11 hypercholesterolemia64 HP:0003124
12 hyperchylomicronemia64 HP:0012238
13 depression64 HP:0000716
14 dementia64 HP:0000726
15 diabetes mellitus64 HP:0000819
16 hepatic steatosis64 HP:0001397
17 failure to thrive64 HP:0001508
18 acute pancreatitis64 HP:0001735
19 nausea and vomiting64 HP:0002017
20 hypertriglyceridemia64 HP:0002155
21 pulmonary embolism64 HP:0002204
22 memory impairment64 HP:0002354
23 perianal abscess64 HP:0009789
24 recurrent pancreatitis64 HP:0100027

GenomeRNAi Phenotypes related to Lipoprotein Lipase Deficiency according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00340-A-110.5APOA1, APOE, LPL
2GR00340-A-28.4APOA1, APOB, APOC3, APOE, CETP, LPA

MGI Mouse Phenotypes related to Lipoprotein Lipase Deficiency according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.0APOB, APOE, BTD, C3, INS, LPL
2MP:00053708.8APOA1, APOB, APOE, C3, INS, LCAT
3MP:00053858.5APOA1, APOB, APOE, C3, INS, LCAT
4MP:00053917.4APOB, APOE, BTD, C3, INS, LCAT
5MP:00053766.8APOA1, APOB, APOE, BTD, C3, INS

Drugs & Therapeutics for Lipoprotein Lipase Deficiency

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Drugs for Lipoprotein Lipase Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 90)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Miconazoleapproved, investigational, vet_approvedPhase 2, Phase 3370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
2
Cyclosporineapproved, investigational, vet_approvedPhase 2, Phase 392279217-60-0, 59865-13-35284373, 6435893
Synonyms:
1c5f
1cyn
30024_FLUKA
30024_SIGMA
59865-13-3
79217-60-0
AC1L1EQW
AC1NQXJE
AC1NR4C4
AC1NUQK3
AC1NUZNC
AC1O5KOG
AC1Q2UDG
Ambap59865-13-3
Ambotz59865-13-3
Antibiotic S 7481F1
BMT-ABA-SAR-MLE-VAL-MLE-ALA-ALA-MLE-MLE-MVA
BMT-ABA-SAR-MLE-VAL-MLE-ALA-DAL-MLE-MLE-MVA
BPBio1_000496
BRD-A64290322-001-01-6
BRD-A69815203-001-04-3
BRD-K13533483-001-03-0
BSPBio_000450
BSPBio_001596
BSPBio_003186
C 3662
C05086
C1832_SIGMA
C3662_SIGMA
C62H111N11O12
CB-01-09 MMX
CHEBI:106343
CHEBI:328305
CHEBI:4031
CHEMBL160
CHEMBL386389
CHEMBL532318
CID2909
CID5280754
CID5284373
CID5458585
CID5497195
CID6435893
CSA
CYCLOSPORIN A (SEE ALSO TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A))
CYCLOSPORIN A, USP
Ciclosporin
Ciclosporin (JP15)
Ciclosporina
Ciclosporine
Ciclosporinum
Cipol N
Cipol-N
Consupren
Consupren S
CsA
CsA & IFN.alpha.
CyA
Cyclokat
Cyclosporin
Cyclosporin A
Cyclosporin A & IFN.alpha.
Cyclosporin A Implant
Cyclosporin A, Tolypocladium inflatum
Cyclosporine (USP)
Cyclosporine A
Cyclosporine [USAN]
D00184
DE-076
DivK1c_000871
EU-0100242
Equoral
GNF-Pf-2808
Gengraf
Gengraf (TN)
HMS1569G12
HMS1791P18
HMS1921L20
HMS1989P18
HMS2089A09
HMS2092F06
HMS502L13
Helv Chim Acta 60: 1568 (1977)
 
I06-0379
I06-0966
IDI1_000871
KBio1_000871
KBio2_000780
KBio2_003348
KBio2_005916
KBio3_002686
KBioGR_001898
KBioSS_000780
LMPK14000003
LS-257
LS-58836
Lopac0_000242
MLS000028376
MLS001333756
MLS002153454
MLS002207033
Mitogard
Modusik-A
MolPort-000-760-988
MolPort-005-934-008
MolPort-006-705-994
NCGC00093704-01
NCGC00093704-02
NCGC00093704-03
NCGC00093704-04
NCGC00093704-05
NCGC00093704-06
NCGC00093704-07
NCGC00093704-08
NCGC00164258-01
NCGC00164258-02
NINDS_000871
NSC290193
Neoplanta
Neoral
Neoral (TN)
NeuroSTAT
Nova-22007
OL 27-400
OL-27400
OLO-400
Papilock
Prestwick2_000435
Prestwick3_000435
Prestwick_731
Pulminiq
Ramihyphin A
Restasis
Restasis (TN)
S-Neoral
S1514_Selleck
SDZ-OXL 400
SMR000058578
SPBio_001467
SPECTRUM1502202
ST-603
Sandimmun
Sandimmun Neoral
Sandimmune
Sandimmune (TN)
Sandimmune, Gengraf, Restasis, Atopica, Sangcya, Cyclosporine
Sang-2000
Sang-35
SangCyA
Sangcya
Sigmasporin
Sigmasporin Microoral
Spectrum2_001484
Spectrum3_001593
Spectrum4_001279
Spectrum5_001628
Spectrum_000300
TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A)
Vekacia
Zyclorin
cyclophorine
cyclosporin A
cyclosporine
from Tolypocladium inflatum (Trichoderma polysporin)
nchembio.184-comp6
nchembio.301-comp5
nchembio.342-comp1
3
Mycophenolic acidapprovedPhase 2, Phase 395224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
4
Mycophenolate mofetilapproved, investigationalPhase 2, Phase 3952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
5
FosamprenavirapprovedPhase 3, Phase 1, Phase 277226700-79-4131536
Synonyms:
((3S)Oxolan-3-yloxy)-N-((1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-(phosphonooxy)propyl)carboxamide
(3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester
226700-79-4
AC1L2ZCO
Amprenavir phosphate
CHEMBL1664
CID131536
Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3S)-tetrahydro-3-furanyl) ester
D02497
DB01319
Fosamprenavir
Fosamprenavir (INN)
Fosamprenavir [INN]
 
GW 433908
GW433908
GW433908A (*Sodium Salt*)
GW433908G (*Calcium Salt*)
HSDB 7340
LS-187013
LS-187787
Lexiva
Lexiva (TM)
MolPort-005-943-058
Telzir
Telzir(TM)
VX 175
VX-175
[(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate
6
Tipranavirapproved, investigationalPhase 2, Phase 373174484-41-465027
Synonyms:
174484-41-4
1d4y
2o4l
2o4n
2o4p
AC1L22FH
AC1Q4JPW
Aptivus
Aptivus (Boehringer Ingelheim)
Aptivus (TN)
Aptivus(TM)
CHEMBL222559
CID65027
 
D08605
DB00932
MolPort-003-850-561
N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE
N-[3-[(1R)-1-[(2R)-6-hydroxy-4-oxo-2-phenethyl-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide
PNU 140690
PNU-140690
PNU-140690E
TPV
Tipranavir
Tipranavir (INN)
U 140690
U-140690
UNII-ZZT404XD09
tipranavir
7
LopinavirapprovedPhase 3344192725-17-092727
Synonyms:
(1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
(2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
(alphaS)-Tetrahydro-N-((alphaS)-alpha-((2S,3S)-2-hydroxy-4-phenyl-3-(2-(2,6-xylyloxy)acetamido)butyl)phenethyl)-alpha-isopropyl-2-oxo-1(2H)-pyrimidineacetamide
1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-, (alphaS)- (9CI)
192725-17-0
1mui
2o4s
2q5k
2rkf
2rkg
A 157378
A 157378.0
A-157378-0
A-157378.0
AB1
ABT 157378
ABT 378
ABT-378
ABT-378, LOPINAVIR
AC1L3OPJ
AIDS032937
 
Aluviran
C12871
C37H48N4O5
CHEBI:40456
CHEMBL729
CID92727
D01425
DB01601
Koletra
LPV
LS-173766
Lopinavir
Lopinavir (JAN/USAN/INN)
Lopinavir [USAN:INN:BAN]
MolPort-003-848-410
N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE
NCGC00164576-01
NCGC00164576-02
RS-346
S1380_Selleck
UNII-2494G1JF75
8
Ritonavirapproved, investigationalPhase 3, Phase 2883155213-67-5392622
Synonyms:
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
155213-67-5
1hxw
1sh9
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S)-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
538, ABT
A-84538
ABBOTT-84538
ABT 538
ABT 84538
ABT-538
ABT538
AC-733
AC1L94GB
AKOS000280930
Abbott 84538
BIDD:GT0387
BIDD:PXR0023
Bio-0093
C07240
C37H48N6O5S2
CHEBI:45409
CHEMBL163
CID392622
CPD000466395
D00427
D019438
 
DB00503
DRG-0244
FT-0082824
HMS2051B08
HSDB 7160
LS-148860
MLS000759541
MLS001424063
MolPort-000-883-877
N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide
NCGC00159462-02
NSC693184
Norvir
Norvir (TM)
Norvir (TN)
Norvir Sec
RIT
RTV
Ritonavir
Ritonavir (JAN/USAN/INN)
Ritonavir [USAN]
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.
Ritonavirum
S1185_Selleck
SAM001246783
SMR000466395
STK634209
ZINC03944422
ritonavir
9
Tenofovirapproved, investigationalPhase 3759147127-20-6464205
Synonyms:
(R)-9-(2-Phosphonomethoxypropyl)adenine
(R)-9-(2-Phosphonylmethoxypropyl)adenine
(R)-9-(2-phosphonomethoxypropyl)adenine
(R)-PMPA
147127-20-6
206184-49-8
AC-760
AC1LA9BO
Anh. tenofovir
Anhydrous tenofovir
Apropovir
CHEBI:45809
CHEMBL483
CID464205
D,L-Tenofovir
DB00300
GNA & Tenofovir
GS 1275
GS 1278
GS1278
 
HHA & Tenofovir
KS-5021
MolPort-003-850-411
NCGC00167535-01
PMPA
PMPA-(R)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Hippeastrum hybrid agglutinin( HHA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI)
Phosphonic acid, [[2-(6-amino-9H-purin-9
S1401_Selleck
TDF
TFV
Tenefovir
Tenofovir
Tenofovir (anh.)
Tenofovir disoproxil
Tenofovir disoproxil fumarate
UNII-99YXE507IL
Viread
Viread, Tenofovir
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
10
Methylprednisoloneapproved, vet_approvedPhase 2, Phase 3119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
11
FluvastatinapprovedPhase 35893957-54-11548972
Synonyms:
(+)-(3R,5S)-fluvastatin
(-)-(3S,5R)-fluvastatin
(3R,5R,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3R,5R,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid
(3S,5R,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(3S,5R,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(E)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
(Z,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoate
7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
93957-54-1
AC1L1FUW
AC1L3TXK
AC1L9J7I
AC1LU7LJ
AC1NS4EB
AC1OC9O5
AC1Q1PZO
BIDD:GT0839
BPBio1_000965
BRD-K03602135-236-02-1
BSPBio_000877
C07014
C24H26FNO4
CHEBI:38562
CHEBI:38565
CHEBI:38567
CHEBI:5136
CHEMBL1078
CHEMBL170417
CID10501876
CID146801
CID1548972
CID3403
 
CID446155
CID5353627
CID6914285
CID9887837
CPD001453708
Canef
Cranoc
D07983
DB01095
Fluindostatin
Fluvas
Fluvas (TN)
Fluvastatin & Primycin
Fluvastatin (INN)
Fluvastatin [INN:BAN]
Fluvastatina
Fluvastatina [INN-Spanish]
Fluvastatine
Fluvastatine [INN-French]
Fluvastatinum
Fluvastatinum [INN-Latin]
HMS2089P06
I06-2297
LS-7404
Lescol
Lescol XL
MolPort-003-847-470
Prestwick0_000859
Prestwick1_000859
Prestwick2_000859
Prestwick3_000859
SAM002548940
SPBio_002798
T6624179
TL8005940
UNII-4L066368AS
XU 62320
XU-62320
fluvastatin
fluvastatin sodium
fluvastatina
fluvastatine
fluvastatinum
nchembio.301-comp9
nchembio790-comp18
12
SimvastatinapprovedPhase 351979902-63-954454
Synonyms:
(+)-Simvastatin
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
79902-63-9
AC-1530
AC1L1H1F
AKOS005111006
ARONIS24119
BCBcMAP01_000007
BIDD:GT0769
BPBio1_001001
BRD-K22134346-001-05-8
BRN 4768037
BSPBio_000909
BSPBio_002337
Bio-0672
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,*aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
C25H38O5
CCRIS 7558
CHEBI:9150
CHEMBL1064
CID54454
CPD000718785
Cholestat
Coledis
Colemin
Corolin
D00434
D019821
DRG-0320
Denan
DivK1c_006991
Eucor
HMS1570N11
HMS1922H13
HMS2089D12
HMS2093E06
HSDB 7208
InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
KBio1_001935
KBio2_002197
KBio2_004765
KBio2_007333
KBio3_001557
KBioGR_001244
KBioSS_002197
KS-1113
Kolestevan
L 644128-000U
LS-46264
Labistatin
Lipex
Lipinorm
Liponorm
Lipovas
Lodales
MK 0733
MK 733
MK-0733
MK-733
MK733
MLS001304029
MLS001333077
MLS001333078
 
MLS002154038
Medipo
Modutrol
MolPort-002-507-345
MolPort-002-885-862
NCGC00017324-01
NCGC00017324-02
NCGC00017324-03
Nivelipol
Nor-Vastina
Pantok
Pepstatin
Prestwick0_000865
Prestwick1_000865
Prestwick2_000865
Prestwick3_000865
Prestwick_171
Rechol
Rendapid
S1792_Selleck
S6196_SIGMA
SAM002589969
SMR000718785
SPBio_001881
SPBio_002830
SPECTRUM1504236
STK801938
Simcor
Simovil
Simvast CR
Simvastatin
Simvastatin & Primycin
Simvastatin (JAN/USP/INN)
Simvastatin [USAN:INN:BAN]
Simvastatin [Usan:Ban:Inn]
Simvastatin lactone
Simvastatin, Compactin
Simvastatina
Simvastatina [Spanish]
Simvastatine
Simvastatine [French]
Simvastatinum
Simvastatinum [Latin]
Simvotin
Sinvacor
Sinvascor
Sivastin
SpecPlus_000895
Spectrum2_001671
Spectrum3_000669
Spectrum4_000632
Spectrum5_001428
Spectrum_001717
Statin
Synvinolin
TNP00259
UNII-AGG2FN16EV
Valemia
Vasotenal
Velostatin
Vytorin
ZINC03780893
Zocor
Zocor (TN)
Zocor, Simlup, Simcard, Simvacor, Simvoget, Zorced, Simvastatin
Zocord
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1-naphthalenyl ester, [1S-[1 alpha,3 alpha,7 beta,8 beta(2S*,4S*),-8a beta
nchembio790-comp16
simvastatin
13
Prednisoloneapproved, vet_approvedPhase 2, Phase 3119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
14
Emtricitabineapproved, investigationalPhase 3457143491-57-060877
Synonyms:
(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-.beta.-L-FTC
(-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-2'-Deoxy-5-fluoro-3'-thiacytidine
(-)-FTC
(-)-beta-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine
(-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(2R-cis)-4-Amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
(2R-cis)-4-amino-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
.beta.-L-(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
1-(2-(Hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine
143491-54-7
143491-57-0
145213-48-5
2',3',5-FTC
2',3'-Dideoxy-5-fluoro-3'-thiacytidine
2'-Deoxy-5-fluoro-3'-oxa-4'-thiocytidine
2'-Deoxy-5-fluoro-3'-thiacytidine
2-FTC
3'-Thia-2'.3'-dideoxy-5-fluorocytidine
4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one
4-Amino-5-fluoro-1-[(2R,5S)-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
4-amino-5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)[1,3]oxathiolan-5-yl]cytosine
524W91
AC1L1U3I
AC1Q4KUB
BW 1592
 
BW 524W91
BW-524W91
BW524W91
C122114
C12599
C8H10FN3O3S
CHEBI:31536
CHEMBL885
CID60877
Coviracil
Coviracil(TM)
D01199
DB00879
DRG-0208
Emtricitabin
Emtricitabina
Emtricitabine
Emtricitabine (JAN/USAN/INN)
Emtricitabinum
Emtriva
Emtriva (TN)
Emtriva(TM)
FT-0080009
HMS2089I05
HSDB 7337
LS-135838
LS-173184
NCGC00164564-01
RCV
Racivir
SBB066061
TL8000958
UNII-G70B4ETF4S
ZINC03629271
beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine
dOTFC
emtricitabine
15
PravastatinapprovedPhase 315081093-37-054687
Synonyms:
(+)-(3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8ar)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acid
(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid
(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-1-Naphthaleneheptanoic acid
3beta-Hydroxycompactin
81093-37-0
81131-70-6 (hydrochloride salt)
AC1L1HJL
AC1Q5T3M
BIDD:GT0773
BRD-K60511616-236-01-4
C01844
C23H36O7
CCRIS 7557
CHEMBL1144
CID54687
Compactin
D08410
DB00175
Elisor
Eptastatin
FT-0082682
KS-5015
LS-94713
Lipostat
Mevalothin
Mevalotin
Mevastatin
Mevinolin
 
Oliprevin
Pravachol
Pravaselect
Pravastatin (INN)
Pravastatin Sodium
Pravastatin Sodium Salt
Pravastatin [INN:BAN]
Pravastatin acid
Pravastatin sodium
Pravastatin tert-Octylamine Salt
Pravastatina
Pravastatina [Spanish]
Pravastatine
Pravastatine [French]
Pravastatinum
Pravastatinum [Latin]
Pravator
Pravator (TN)
RMS-431
SQ-31,000
Selectin
Selektine
Selipran
UNII-KXO2KT9N0G
Vasten
nchembio.301-comp7
nchembio790-comp15
pravastatin
pravastatina
pravastatine
pravastatinum
16
PitavastatinapprovedPhase 366147511-69-1, 147526-32-76366718, 5282452
Synonyms:
( )-(3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoic acid
(3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-7-(2-Cyclopropyl-4-(p-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoic acid
(3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
111GE002
147511-69-1
147526-32-7
2C25H23FNO4.Ca
AC1NR03G
AC1NR03J
AKOS005145916
Alipza
Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate), monocalcium salt
C13334
CCRIS 8652
CID5282451
CID5282452
D01862
Itavastatin
Itavastatin calcium
KS-1220
LS-190698
 
LS-74594
LS-74595
Livalo
Livalo (TN)
Livalo, Pitavastatin calcium
Livazo
MolPort-006-822-984
NK 104
NK-104
NKS-104
Nisvastatin
P 872441
P-872441
Pitavastatia
Pitavastatin
Pitavastatin [INN]
Pitavastatin calcium
Pitavastatin calcium (JAN)
Pitavastatin hemicalcium
Pitavastatine
Pitavastatinum
S1759_Selleck
ZINC01534965
calcium (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate
17
Folic Acidapproved, nutraceutical, vet_approvedPhase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
18
Niacinapproved, investigational, nutraceuticalPhase 392359-67-6938
Synonyms:
3-Carboxylpyridine
3-Carboxypyridine
3-Pyridinecarboxylate
3-Pyridinecarboxylic acid
3-Pyridylcarboxylate
3-Pyridylcarboxylic acid
3-carboxypyridine
Acide Nicotinique
Acido nicotinico
Acidum Nicotinicum
Akotin
Anti-pellagra vitamin
Apelagrin
Daskil
Efacin
Enduracin
Linic
M-Pyridinecarboxylic Acid
Niac
Niacin
Niacine
Niacor
Nicacid
Nicamin
Nicangin
 
Nico-Span
Nicobid
Nicocap
Nicodelmine
Nicolar
Niconacid
Nicosan 3
Nicotinate
Nicotinic Acid
Nicotinic acid
Nicotinipca
Nicyl
Nikotinsaeure
Nyclin
P.P. factor
PP Factor
Pellagra preventive factor
Pellagrin
Pelonin
Pyridine-beta-carboxylic acid
Slo-niacin
Vitamin B3
Wampocap
beta-Pyridinecarboxylic acid
pyridine-β-carboxylic acid
β-pyridinecarboxylic acid
19
Nicotinamideapproved, NutraceuticalPhase 391998-92-0936
Synonyms:
.beta.-Pyridinecarboxamide
11032-50-1
123574-63-0
1yc5
3 Pyridinecarboxamide
3-Carbamoylpyridine
3-Pyridinecarboxamide
3-Pyridinecarboxylic acid amide
37321-14-5
47865U_SUPELCO
55600-01-6
63748-44-7
72340_FLUKA
72340_SIGMA
72347_FLUKA
78731-47-2
98-92-0
A186B02E-6C70-4E54-9739-79398D439AAA
AC-907/25014114
AC1L1ACZ
AC1Q4ZFV
AI3-02906
Acid amide
Amid kyseliny nikotinove
Amid kyseliny nikotinove [Czech]
Amide PP
Aminicotin
Amixicotyn
Amnicotin
Astra Brand of Niacinamide
Austrovit PP
B 3, Vitamin
B3, Vitamin
BB_NC-2290
Benicot
C00153
C6H6N2O
CCRIS 1901
CHEBI:17154
CHEMBL1140
CID936
CPD000058212
D00036
D009536
DB02701
DEA No. 1405
Delonin Amide
Delonin amide
Dipegyl
Dipigyl
EINECS 202-713-4
EINECS 234-265-0
Endobion
Enduramide
Factor pp
HMS2052M21
HMS2090B05
HMS2093H03
HSDB 1237
Hansamid
I02-1741
I02-2250
InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9
Inovitan PP
Jenapharm Brand of Niacinamide
Jenapharm, Nicotinsaureamid
LS-2051
MLS000069714
Mediatric
Merck Brand of Niacinamide
MolMap_000061
MolPort-001-783-876
N0078
N0636_SIGMA
N2142_SIGMA
N3376_SIGMA
N5535_SIAL
NAM
NCGC00093354-03
NCGC00093354-04
NSC 13128
NSC13128
NSC27452
Nandervit-N
Niacevit
Niacinamide
Niacinamide (USP)
Niacinamide Astra Brand
Niacinamide Jenapharm Brand
Niacinamide Merck Brand
 
Niacinamide Pharmagenix Brand
Niacinamide [USAN]
Niacinamide, Nicotinic acid amide, Nicotinamide
Niacotinamide
Niamide
Niavit PP
Nicamide
Nicamina
Nicamindon
Nicasir
Nicobion
Nicofort
Nicogen
Nicomidol
Nicosan 2
Nicosylamide
Nicota
Nicotamide
Nicotilamide
Nicotililamido
Nicotinamid
Nicotinamida
Nicotinamida [INN-Spanish]
Nicotinamide
Nicotinamide (JP15/INN)
Nicotinamide (Niacinamide)
Nicotinamide, niacin, vitamin B3
Nicotinamide-carbonyl-14C
Nicotinamidum
Nicotinamidum [INN-Latin]
Nicotine acid amide
Nicotine amide
Nicotinic acid amide
Nicotinic amide
Nicotinsaeureamid
Nicotinsaureamid
Nicotinsaureamid Jenapharm
Nicotinsaureamid [German]
Nicotol
Nicotylamide
Nicotylamidum
Nicovel
Nicovit
Nicovitina
Nicovitol
Nicozymin
Nictoamide
Nikasan
Nikazan
Niko-tamin
Nikotinamid
Nikotinsaeureamid
Nikotinsaeureamid [German]
Niocinamide
Niozymin
PP-Faktor
Papulex
Pelmin
Pelmine
Pelonin amide
Pharmagenix Brand of Niacinamide
Propamine A
Pyridine-3-carboxylic acid amide
S1899_Selleck
SAM001246860
SGCUT00176
SMR000058212
Savacotyl
UNII-25X51I8RD4
Vi-Nicotyl
Vi-noctyl
Vitamin B
Vitamin B (VAN)
Vitamin B 3
Vitamin B3 amide
Vitamin H1
Vitamin PP
WLN: T6NJ CVZ
Witamina PP
ZINC00005878
b-Pyridinecarboxamide
beta-Pyridinecarboxamide
bmse000281
m-(Aminocarbonyl)pyridine
nchembio.154-comp4
nchembio.73-comp6
niacin - Vitamin B3
niacinamide
nicotinamide
pyridine-3-carboxamide
to_000073
vitamin PP
20Antirheumatic AgentsPhase 2, Phase 310956
21Anti-Infective AgentsPhase 2, Phase 322062
22Antifungal AgentsPhase 2, Phase 33696
23Antibiotics, AntitubercularPhase 2, Phase 37180
24Dermatologic AgentsPhase 2, Phase 35806
25Calcineurin InhibitorsPhase 2, Phase 31622
26Immunosuppressive AgentsPhase 2, Phase 313086
27Anti-Bacterial AgentsPhase 2, Phase 311226
28VitaminsPhase 35282
29
AnacetrapibPhase 316875446-37-0
Synonyms:
875446-37-0
Anacetrapib
Anacetrapib (USAN)
CID 11556427
 
CID11556427
D08855
MK-0859
MK0859
UNII-P7T269PR6S
30Vitamin B ComplexPhase 34337
31Nicotinic AcidsPhase 3923
32OxazolidinonesPhase 347
33Trace ElementsPhase 36001
34Vasodilator AgentsPhase 33543
35HIV Integrase InhibitorsPhase 3397
36Integrase InhibitorsPhase 3418
37HIV Protease InhibitorsPhase 3, Phase 25470
38Nucleic Acid Synthesis InhibitorsPhase 34962
39
protease inhibitorsPhase 3, Phase 25471
Synonyms:
 
protease inhibitors
40Reverse Transcriptase InhibitorsPhase 31913
41Raltegravir PotassiumPhase 3292
42MicronutrientsPhase 36001
43Emtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationPhase 3248
44Anti-Retroviral AgentsPhase 3, Phase 23296
45Anti-HIV AgentsPhase 3, Phase 23162
46Antiviral AgentsPhase 3, Phase 29967
47Cytochrome P-450 CYP3A InhibitorsPhase 3, Phase 21715
48Cytochrome P-450 Enzyme InhibitorsPhase 3, Phase 23917
49Calcium, DietaryPhase 35713
50AntimetabolitesPhase 312054

Interventional clinical trials:

(show all 34)
idNameStatusNCT IDPhase
1Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]Unknown statusNCT01109498Phase 2, Phase 3
2A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia SyndromeCompletedNCT01514461Phase 3
3The APPROACH Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia SyndromeCompletedNCT02211209Phase 3
4Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient SubjectsCompletedNCT00891306Phase 2, Phase 3
5Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying TherapyCompletedNCT01623115Phase 3
6A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial HypercholesterolemiaCompletedNCT01968980Phase 3
7Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)CompletedNCT02107898Phase 3
8Lipid Efficacy Study (0524B-022)(COMPLETED)CompletedNCT00269217Phase 3
9A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)CompletedNCT01824238Phase 3
10Atorvastatin Three Year Pediatric StudyCompletedNCT00827606Phase 3
11Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024)CompletedNCT00289900Phase 3
12Study Comparing Lopinavir/Ritonavir (LPV/r) + Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) With a Nucleoside Sparing Regimen Consisting of Lopinavir/Ritonavir + Raltegravir (RAL)CompletedNCT00711009Phase 3
13Rollover Trial Safety and Tolerability of Combination Tipranavir and Ritonavir Use in HIV 1 Infected SubjectsCompletedNCT00146328Phase 2, Phase 3
14The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia SyndromeRecruitingNCT02658175Phase 3
15Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.TerminatedNCT01589237Phase 3
16Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)TerminatedNCT01841684Phase 3
17Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of CareTerminatedNCT01410383Phase 3
18Pilot Study To Assess CAT-2003 in Patients With ChylomicronemiaCompletedNCT02098278Phase 2
19Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe HypertriglyceridemiaCompletedNCT01146522Phase 1, Phase 2
20A Pilot Study to Evaluate the Lipid Effects of TRIA-662CompletedNCT02008084Phase 2
21Study to Evaluate the Effects of MBX-8025 in Patients With HoFHCompletedNCT02472535Phase 2
2248-Week Study Of GW433908 And Ritonavir Or GW433908 Alone, Twice Daily In Pediatric Patients With HIV InfectionCompletedNCT00089583Phase 2
23Orlistat for the Treatment of Type I HyperlipoproteinemiaRecruitingNCT02767531Phase 2
24Alipogene Tiparvovec for the Treatment of LPLD PatientsRecruitingNCT02904772Phase 2
25Phase 2 Study of Orlistat and SLx-4090 for the Treatment of Type 1 HyperlipoproteinemiaRecruitingNCT01675154Phase 2
26Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric SubjectsActive, not recruitingNCT00071760Phase 2
27Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial HypercholesterolemiaCompletedNCT00004809Phase 1
28Study to Re-assess and Re-confirm Data Previously Recorded About the Incidence and Severity of Acute Abdominal "Pancreatitis" Episodes in Lipoprotein Lipase Deficient (LPLD) Subjects Previously Enrolled on AMT Clinical StudiesUnknown statusNCT01448577
29Effect of Weight Loss on Cholesterol Metabolism in Hereditary Hypercholesterolemias and Overweight or Obesity.CompletedNCT01995149
30Following Lipectomy to Understand Adipose Tissue Re-accumulationCompletedNCT00995631
31Russian Familial Hypercholesterolemia RegistryRecruitingNCT02208869
32Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, GermanyEnrolling by invitationNCT02750527
33Lipoprotein Lipase Enzyme Activity Assay Validation and Clinical AssessmentNot yet recruitingNCT02656095
34Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other StudiesTerminatedNCT01447901

Search NIH Clinical Center for Lipoprotein Lipase Deficiency

Genetic Tests for Lipoprotein Lipase Deficiency

About this section

Genetic tests related to Lipoprotein Lipase Deficiency:

id Genetic test Affiliating Genes
1 Hyperlipoproteinemia, Type I27
2 Familial Chylomicronemia Syndrome27

Anatomical Context for Lipoprotein Lipase Deficiency

About this section

MalaCards organs/tissues related to Lipoprotein Lipase Deficiency:

36
Endothelial, Heart, Monocytes, Kidney, Bone, Skin

Publications for Lipoprotein Lipase Deficiency

About this section

Articles related to Lipoprotein Lipase Deficiency:

(show top 50)    (show all 160)
idTitleAuthorsYear
1
Eruptive Xanthomas in Lipoprotein Lipase Deficiency. (28529016)
2017
2
Homozygous LPL p.Gly188Glu Mutation in a Mexican Girl With Lipoprotein Lipase Deficiency. (28445021)
2017
3
Extreme hypertriglyceridemia, pseudohyponatremia, and pseudoacidosis in a neonate with lipoprotein lipase deficiency due to segmental uniparental disomy. (28438574)
2017
4
Lipoprotein Lipase Deficiency (R243H) in a Type 2 Diabetes Patient with Multiple Arterial Aneurysms. (27150867)
2016
5
The role of registries in rare genetic lipid disorders: Review and introduction of the first global registry in lipoprotein lipase deficiency. (28284702)
2016
6
Long-Term Retrospective Analysis of Gene Therapy with Alipogene Tiparvovec and Its Effect on Lipoprotein Lipase Deficiency-Induced Pancreatitis. (27412455)
2016
7
Lipoprotein lipase deficiency presenting with neonatal perianal abscesses. (26825936)
2016
8
Lipaemia in lipoprotein lipase deficiency. (27329915)
2016
9
Lipaemia in lipoprotein lipase deficiency. (27329913)
2016
10
A 19 year follow-up of a woman with lipoprotein lipase deficiency treated with biliopancreatic diversion. (26734140)
2015
11
Issues Affecting Quality of Life and Disease Burden in Lipoprotein Lipase Deficiency (Lpld) - First Step Towards a Pro Measure in Lpld. (26533960)
2015
12
Cost-Effectiveness Analysis of Glybera for The Treatment of Lipoprotein Lipase Deficiency. (26534236)
2015
13
Type I hyperlipidaemia caused by lipoprotein lipase deficiency in a nurseling: the role of the clinical laboratory in processing biological samples and contributing to the diagnosis and therapeutic follow-up of patients. (26489817)
2015
14
Lipoprotein lipase deficiency leads to I+-synuclein aggregation and ubiquitin C-terminal hydrolase L1 reduction. (25595992)
2015
15
Alipogene tiparvovec: a review of its use in adults with familial lipoprotein lipase deficiency. (25559420)
2015
16
Lipoprotein lipase deficiency: clinical, biochemical and molecular characteristics in three patients with novel mutations in the LPL gene. (25863041)
2014
17
Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiency. (24795752)
2014
18
Alipogene tiparvovec for the treatment of lipoprotein lipase deficiency. (23527320)
2013
19
Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial. (22717743)
2013
20
Gestational hyperlipidemia and acute pancreatitis with underlying partial lipoprotein lipase deficiency and apolipoprotein E3/E2 genotype. (24009459)
2013
21
Alipogene tiparvovec: gene therapy for lipoprotein lipase deficiency. (23126631)
2013
22
Severe Hypertriglyceridemia in a Newborn with Monogenic Lipoprotein Lipase Deficiency: An Unconventional Therapeutic Approach with Exchange Transfusion. (24142281)
2013
23
Adipose-specific lipoprotein lipase deficiency more profoundly affects brown than white fat biology. (23542081)
2013
24
Familial lipoprotein lipase deficiency: a case of compound heterozygosity of a novel duplication (R44Kfs*4) and a common mutation (N291S) in the lipoprotein lipase gene. (23761384)
2013
25
Molecular analysis of chylomicronemia in a clinical laboratory setting: Diagnosis of 13 cases of lipoprotein lipase deficiency. (24291057)
2013
26
Metabolic surgery for the treatment of hypertriglyceridemia-related pancreatitis due to familial lipoprotein lipase deficiency. (24680758)
2013
27
Lipoprotein abnormalities in compound heterozygous lipoprotein lipase deficiency after treatment with a low-fat diet and orlistat. (23415432)
2013
28
Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPLS447X) in a phase II clinical trial of Lipoprotein Lipase deficiency (LPLD) gene therapy. (24299335)
2013
29
Lipoprotein lipase deficiency in chronic kidney disease is accompanied by down-regulation of endothelial GPIHBP1 expression. (22009636)
2012
30
Gene therapy for lipoprotein lipase deficiency. (22691709)
2012
31
11-Year follow-up in biliopancreatic diversion for recurrent pancreatitis due to lipoprotein lipase deficiency. (21415674)
2011
32
Lipoprotein lipase deficiency in an infant. (22080683)
2011
33
A sweet heart: increased cardiac glucose uptake in patients with lipoprotein lipase deficiency. (21845510)
2011
34
Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency. (20427244)
2010
35
Hyperlipidemia resulting in abnormal density and signal intensity of blood in a neonate with lipoprotein lipase deficiency. (20037129)
2010
36
Lipoprotein lipase deficiency with visceral xanthomas. (20143060)
2010
37
Lipoprotein lipase deficiency is associated with elevated acylation stimulating protein plasma levels. (19237736)
2009
38
Enhanced susceptibility to pancreatitis in severe hypertriglyceridaemic lipoprotein lipase-deficient mice and agonist-like function of pancreatic lipase in pancreatic cells. (18936103)
2009
39
Alipogene tiparvovec, an adeno-associated virus encoding the Ser(447)X variant of the human lipoprotein lipase gene for the treatment of patients with lipoprotein lipase deficiency. (20072945)
2009
40
The role of free fatty acids, pancreatic lipase and Ca+ signalling in injury of isolated acinar cells and pancreatitis model in lipoprotein lipase-deficient mice. (18983441)
2009
41
Presynaptic defects underlying impaired learning and memory function in lipoprotein lipase-deficient mice. (19357293)
2009
42
Familial lipoprotein lipase deficiency caused by known (G188E) and novel (W394X) LPL gene mutations. (18275685)
2008
43
Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet. (18032735)
2008
44
Xanthoma of bone associated with lipoprotein lipase deficiency. (18828009)
2008
45
Familial lipoprotein lipase deficiency]. (17824045)
2007
46
A novel complex deletion-insertion mutation mediated by Alu repetitive elements leads to lipoprotein lipase deficiency. (17706445)
2007
47
Glucose-stimulated insulin response in non-diabetic patients with lipoprotein lipase deficiency and hypertriglyceridemia. (16256241)
2006
48
Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation. (16716106)
2006
49
A novel substitution at the translation initiator codon (ATG-->ATC) of the lipoprotein lipase gene is mainly responsible for lipoprotein lipase deficiency in a patient with severe hypertriglyceridemia and recurrent pancreatitis. (16431216)
2006
50
Hyperchylomicronaemia due to lipoprotein lipase deficiency as a cause of false-positive newborn screening for biotinidase deficiency. (15877202)
2005

Variations for Lipoprotein Lipase Deficiency

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UniProtKB/Swiss-Prot genetic disease variations for Lipoprotein Lipase Deficiency:

70 (show all 70)
id Symbol AA change Variation ID SNP ID
1LPLp.Arg102SerVAR_004211rs118204073
2LPLp.Trp113GlyVAR_004212
3LPLp.Trp113ArgVAR_004213rs118204069
4LPLp.His163ArgVAR_004214
5LPLp.Gly169GluVAR_004215rs118204063
6LPLp.Gly181SerVAR_004216
7LPLp.Asp183GlyVAR_004217rs118204064
8LPLp.Asp183AsnVAR_004218
9LPLp.Pro184ArgVAR_004219
10LPLp.Ala185ThrVAR_004220rs748349562
11LPLp.Ser199CysVAR_004221rs118204072
12LPLp.Ala203ThrVAR_004222rs118204056
13LPLp.Asp207GluVAR_004223rs118204076
14LPLp.His210GlnVAR_004224
15LPLp.Gly215GluVAR_004225rs118204057
16LPLp.Ser220ArgVAR_004226rs757546424
17LPLp.Ile221ThrVAR_004227rs118204061
18LPLp.Gly222GluVAR_004228rs118204075
19LPLp.Asp231GluVAR_004229rs118204067
20LPLp.Ile232SerVAR_004230rs770601263
21LPLp.Pro234LeuVAR_004231rs118204060
22LPLp.Cys243SerVAR_004232
23LPLp.Arg270HisVAR_004233rs118204062
24LPLp.Ser271ThrVAR_004234rs28934893
25LPLp.Asp277AsnVAR_004235rs118204068
26LPLp.Ser278CysVAR_004236
27LPLp.Ser286GlyVAR_004237
28LPLp.Ser286ArgVAR_004238
29LPLp.Asn318SerVAR_004239rs268
30LPLp.Met328ThrVAR_004240
31LPLp.Leu330ProVAR_004241
32LPLp.Ala361ThrVAR_004242rs118204071
33LPLp.Leu392ValVAR_004243rs118204078
34LPLp.Glu437LysVAR_004245
35LPLp.Glu437ValVAR_004246
36LPLp.Asp36AsnVAR_011948rs1801177
37LPLp.Ala288ThrVAR_011949rs1800011
38LPLp.Asn70SerVAR_057914
39LPLp.Val96LeuVAR_057915rs373088068
40LPLp.Ala98ThrVAR_057916rs145657341
41LPLp.Thr128AlaVAR_057917
42LPLp.Gly132ArgVAR_057918
43LPLp.Gly181ValVAR_057919
44LPLp.Asp183HisVAR_057920rs781614031
45LPLp.Gly186GluVAR_057921
46LPLp.Glu190GlyVAR_057922
47LPLp.Asp201ValVAR_057923
48LPLp.Val208IleVAR_057924rs568397156
49LPLp.His210AspVAR_057925
50LPLp.Gly215ArgVAR_057926
51LPLp.Lys225ArgVAR_057927
52LPLp.Val227AlaVAR_057928rs528243561
53LPLp.Ile252ThrVAR_057929rs118204080
54LPLp.Cys266TrpVAR_057930rs118204082
55LPLp.Arg270CysVAR_057931rs118204077
56LPLp.Leu279ArgVAR_057932rs35414700
57LPLp.Leu279ValVAR_057933rs371282890
58LPLp.Tyr289HisVAR_057934
59LPLp.Phe297LeuVAR_057935
60LPLp.Leu303PheVAR_057936
61LPLp.Cys305ArgVAR_057937rs773235712
62LPLp.Cys310TyrVAR_057938
63LPLp.Leu313ProVAR_057939
64LPLp.Ser325ArgVAR_057940rs761265900
65LPLp.Met328ArgVAR_057941
66LPLp.Leu330PheVAR_057942
67LPLp.Ser365PheVAR_057943rs546542623
68LPLp.Cys445TyrVAR_057944rs118204079
69LPLp.Glu448LysVAR_057945rs149089920
70LPLp.Met404ArgVAR_077541

Clinvar genetic disease variations for Lipoprotein Lipase Deficiency:

5 (show all 38)
id Gene Variation Type Significance SNP ID Assembly Location
1LPLNM_ 000237.2(LPL): c.607G> A (p.Ala203Thr)SNVPathogenicrs118204056GRCh37Chr 8, 19811696: 19811696
2LPLLPL, INSinsertionPathogenic
3LPLnsv513798duplicationPathogenic
4LPLNM_ 000237.2(LPL): c.644G> A (p.Gly215Glu)SNVPathogenicrs118204057GRCh37Chr 8, 19811733: 19811733
5LPLLPL, 6-KB DELdeletionPathogenic
6LPLNM_ 000237.2(LPL): c.397C> T (p.Gln133Ter)SNVPathogenicrs118204058GRCh37Chr 8, 19809427: 19809427
7LPLNM_ 000237.2(LPL): c.811T> A (p.Ser271Thr)SNVPathogenicrs118204059GRCh37Chr 8, 19813387: 19813387
8LPLLPL, IVS2DS, G-ASNVPathogenic
9LPLNM_ 000237.2(LPL): c.701C> T (p.Pro234Leu)SNVPathogenicrs118204060GRCh37Chr 8, 19811790: 19811790
10LPLNM_ 000237.2(LPL): c.693C> G (p.Asp231Glu)SNVPathogenicrs118204067GRCh37Chr 8, 19811782: 19811782
11LPLNM_ 000237.2(LPL): c.662T> C (p.Ile221Thr)SNVPathogenicrs118204061GRCh37Chr 8, 19811751: 19811751
12LPLNM_ 000237.2(LPL): c.809G> A (p.Arg270His)SNVPathogenicrs118204062GRCh37Chr 8, 19813385: 19813385
13LPLNM_ 000237.2(LPL): c.300C> A (p.Tyr100Ter)SNVPathogenicrs118204074GRCh37Chr 8, 19809330: 19809330
14LPLNM_ 000237.2(LPL): c.506G> A (p.Gly169Glu)SNVPathogenicrs118204063GRCh37Chr 8, 19810897: 19810897
15LPLNM_ 000237.2(LPL): c.548A> G (p.Asp183Gly)SNVPathogenicrs118204064GRCh37Chr 8, 19811637: 19811637
16LPLLPL, IVS2DS, G-A, +1SNVPathogenic
17LPLNM_ 000237.2(LPL): c.264T> A (p.Tyr88Ter)SNVPathogenicrs118204065GRCh37Chr 8, 19809294: 19809294
18LPLNM_ 000237.2(LPL): c.1227G> A (p.Trp409Ter)SNVPathogenicrs118204066GRCh37Chr 8, 19818499: 19818499
19LPLLPL, 1-BP DEL, 916GdeletionPathogenic
20LPLNM_ 000237.2(LPL): c.829G> A (p.Asp277Asn)SNVPathogenicrs118204068GRCh37Chr 8, 19813405: 19813405
21LPLNM_ 000237.2(LPL): c.337T> C (p.Trp113Arg)SNVPathogenicrs118204069GRCh37Chr 8, 19809367: 19809367
22LPLNM_ 000237.2(LPL): c.272G> A (p.Trp91Ter)SNVPathogenicrs118204070GRCh37Chr 8, 19809302: 19809302
23LPLLPL, IVS1, G-C, +1SNVPathogenic
24LPLNM_ 000237.2(LPL): c.1081G> A (p.Ala361Thr)SNVPathogenicrs118204071GRCh37Chr 8, 19816833: 19816833
25LPLNM_ 000237.2(LPL): c.596C> G (p.Ser199Cys)SNVPathogenicrs118204072GRCh37Chr 8, 19811685: 19811685
26LPLNM_ 000237.2(LPL): c.306A> C (p.Arg102Ser)SNVPathogenicrs118204073GRCh37Chr 8, 19809336: 19809336
27LPLNM_ 000237.2(LPL): c.665G> A (p.Gly222Glu)SNVPathogenicrs118204075GRCh37Chr 8, 19811754: 19811754
28LPLNM_ 000237.2(LPL): c.621C> G (p.Asp207Glu)SNVPathogenicrs118204076GRCh37Chr 8, 19811710: 19811710
29LPLNM_ 000237.2(LPL): c.808C> T (p.Arg270Cys)SNVPathogenicrs118204077GRCh37Chr 8, 19813384: 19813384
30LPLNM_ 000237.2(LPL): c.1174C> G (p.Leu392Val)SNVPathogenicrs118204078GRCh37Chr 8, 19818446: 19818446
31LPLNM_ 000237.2(LPL): c.106G> A (p.Asp36Asn)SNVrisk factorrs1801177GRCh37Chr 8, 19805708: 19805708
32LPLNM_ 000237.2(LPL): c.1334G> A (p.Cys445Tyr)SNVPathogenicrs118204079GRCh37Chr 8, 19819637: 19819637
33LPLNM_ 000237.2(LPL): c.755T> C (p.Ile252Thr)SNVPathogenicrs118204080GRCh37Chr 8, 19811844: 19811844
34LPLNM_ 000237.2(LPL): c.987C> A (p.Tyr329Ter)SNVPathogenicrs118204081GRCh37Chr 8, 19813563: 19813563
35LPLNM_ 000237.2(LPL): c.798C> G (p.Cys266Trp)SNVPathogenicrs118204082GRCh37Chr 8, 19813374: 19813374
36LPLLPL, 1-BP DEL, CODON 172deletionPathogenic
37LPLNM_ 000237.2(LPL): c.928T> C (p.Cys310Arg)SNVLikely pathogenicrs886037774GRCh37Chr 8, 19813504: 19813504
38LPLNM_ 000237.2(LPL): c.1187A> T (p.Glu396Val)SNVLikely pathogenicrs886037775GRCh38Chr 8, 19960948: 19960948

Expression for genes affiliated with Lipoprotein Lipase Deficiency

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Search GEO for disease gene expression data for Lipoprotein Lipase Deficiency.

Pathways for genes affiliated with Lipoprotein Lipase Deficiency

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Pathways related to Lipoprotein Lipase Deficiency according to GeneCards Suite gene sharing:

(show all 11)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.7APOA1, APOB, PNLIP
2
Show member pathways
9.7APOA1, APOB, APOE
3
Show member pathways
9.2APOA1, APOB, APOE, INS
49.2APOA1, APOB, BTD, PNLIP
59.1APOA1, APOC3, PLTP
6
Show member pathways
8.9APOA1, APOB, APOC3, APOE, LPL, PNLIP
78.8APOA1, APOC3, LPL, PLTP
8
Show member pathways
8.3APOA1, APOB, APOC3, APOE, BTD, LPL
9
Show member pathways
7.7APOA1, APOB, APOC3, APOE, CETP, LCAT
10
Show member pathways
7.0APOA1, APOB, APOC3, APOE, CETP, LCAT
11
Show member pathways
5.0APOA1, APOB, APOC3, APOE, BTD, CETP

GO Terms for genes affiliated with Lipoprotein Lipase Deficiency

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Cellular components related to Lipoprotein Lipase Deficiency according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1endosome lumenGO:003190410.6APOB, INS
2endocytic vesicle lumenGO:007168210.5APOA1, APOB, APOE
3early endosomeGO:000576910.1APOA1, APOB, APOC3, APOE
4chylomicronGO:00426279.9APOA1, APOB, APOC3, APOE, LPL
5intermediate-density lipoprotein particleGO:00343639.9APOA1, APOB, APOC3, APOE
6secretory granule lumenGO:00347749.7APOA1, C3, INS
7low-density lipoprotein particleGO:00343629.7APOA1, APOB, APOE, PLA2G7
8blood microparticleGO:00725629.6APOA1, APOE, C3, PON1
9spherical high-density lipoprotein particleGO:00343669.6APOA1, APOC3, PON1
10endoplasmic reticulum lumenGO:00057889.6APOA1, APOB, APOE, C3, INS
11high-density lipoprotein particleGO:00343649.2APOA1, APOE, CETP, LCAT, PON1
12very-low-density lipoprotein particleGO:00343619.1APOA1, APOB, APOC3, APOE, LPL
13extracellular exosomeGO:00700627.7APOA1, APOB, APOC3, APOE, BTD, C3
14extracellular spaceGO:00056155.7APOA1, APOB, APOC3, APOE, BTD, C3
15extracellular regionGO:00055765.2APOA1, APOB, APOC3, APOE, BTD, C3

Biological processes related to Lipoprotein Lipase Deficiency according to GeneCards Suite gene sharing:

(show all 48)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of cholesterol storageGO:001088610.8APOB, LPL
2positive regulation of macrophage derived foam cell differentiationGO:001074410.8APOB, LPL
3artery morphogenesisGO:004884410.7APOB, APOE
4lipoprotein catabolic processGO:004215910.7APOB, APOE
5high-density lipoprotein particle assemblyGO:003438010.7APOA1, APOE
6high-density lipoprotein particle clearanceGO:003438410.7APOA1, APOE
7neuron projection regenerationGO:003110210.7APOA1, APOE
8positive regulation of cholesterol esterificationGO:001087310.7APOA1, APOE
9negative regulation of very-low-density lipoprotein particle remodelingGO:001090310.7APOA1, APOC3
10phospholipid homeostasisGO:005509110.6APOA1, CETP
11lipid homeostasisGO:005508810.6APOE, CETP
12fatty acid homeostasisGO:005508910.5APOE, INS
13positive regulation of lipid storageGO:001088410.5APOB, C3
14positive regulation of lipid biosynthetic processGO:004688910.5APOE, INS
15positive regulation of nitric-oxide synthase activityGO:005100010.5APOE, INS
16negative regulation of lipid catabolic processGO:005099510.5APOC3, INS
17phospholipid metabolic processGO:000664410.5APOA1, LCAT, LPL
18chylomicron remnant clearanceGO:003438210.4APOB, APOC3, APOE
19phospholipid effluxGO:003370010.3APOA1, APOC3, APOE
20regulation of Cdc42 protein signal transductionGO:003248910.3APOA1, APOC3, APOE
21very-low-density lipoprotein particle assemblyGO:003437910.2APOB, APOC3
22lipoprotein biosynthetic processGO:004215810.1APOA1, APOB, APOE, LCAT
23cholesterol effluxGO:003334410.1APOA1, APOB, APOC3, APOE
24chylomicron assemblyGO:003437810.1APOA1, APOB, APOC3, APOE
25cholesterol transportGO:003030110.1APOA1, APOB, CETP, LCAT
26very-low-density lipoprotein particle clearanceGO:003444710.1APOB, APOE
27receptor-mediated endocytosisGO:000689810.1APOA1, APOB, APOE, CETP
28phosphatidylcholine metabolic processGO:004647010.0CETP, LCAT, PON1
29post-translational protein modificationGO:00436879.9APOA1, APOB, APOE, C3
30chylomicron remodelingGO:00343719.9APOA1, APOB, APOC3, APOE, LPL
31steroid metabolic processGO:00082029.8APOA1, APOB, APOE, CETP, LCAT
32reverse cholesterol transportGO:00436919.7APOA1, APOC3, APOE, CETP, LCAT
33lipid catabolic processGO:00160429.7APOB, APOC3, LPL, PLA2G7, PNLIP
34triglyceride metabolic processGO:00066419.6APOC3, APOE, CETP, LPL
35triglyceride catabolic processGO:00194339.6APOA1, APOB, APOC3, APOE, LPL
36retinoid metabolic processGO:00015239.6APOA1, APOB, APOC3, APOE, LPL, PNLIP
37cellular protein metabolic processGO:00442679.6APOA1, APOB, APOE, C3, INS
38positive regulation of cholesterol effluxGO:00108759.5APOE, PLTP, PON1
39triglyceride homeostasisGO:00703289.5APOA1, APOC3, APOE, CETP, LPL
40low-density lipoprotein particle remodelingGO:00343749.4APOB, APOE, CETP, LPA, PLA2G7
41very-low-density lipoprotein particle remodelingGO:00343729.3APOE, CETP, LCAT, LPL
42cholesterol homeostasisGO:00426329.3APOA1, APOB, APOC3, APOE, CETP, LCAT
43cholesterol metabolic processGO:00082039.2APOA1, APOB, APOE, CETP, LCAT, PON1
44high-density lipoprotein particle remodelingGO:00343758.9APOA1, APOC3, APOE, CETP, LCAT, PLTP
45lipoprotein metabolic processGO:00421578.9APOA1, APOB, APOC3, APOE, CETP, LCAT
46lipid transportGO:00068698.6APOA1, APOB, APOC3, APOE, CETP, LPA
47transportGO:00068108.3APOA1, APOB, APOC3, APOE, CETP, LPA
48lipid metabolic processGO:00066296.2APOA1, APOB, APOC3, APOE, C3, CETP

Molecular functions related to Lipoprotein Lipase Deficiency according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1apolipoprotein bindingGO:003418510.5LPA, LPL
2high-density lipoprotein particle receptor bindingGO:007065310.5APOA1, APOC3
3lipase inhibitor activityGO:005510210.5APOA1, APOC3
4low-density lipoprotein particle receptor bindingGO:005075010.5APOB, APOE
5lipoprotein particle bindingGO:007181310.5APOA1, APOE
6phosphatidylcholine-sterol O-acyltransferase activator activityGO:006022810.5APOA1, APOE
7phosphatidylcholine bindingGO:003121010.4APOA1, CETP
8triglyceride bindingGO:001712910.2CETP, LPL
9phospholipid transporter activityGO:000554810.2APOA1, CETP
10triglyceride lipase activityGO:000480610.0LPL, PNLIP
11cholesterol transporter activityGO:001712710.0APOA1, APOB, APOE, CETP
12heparin bindingGO:000820110.0APOB, APOE, LPA, LPL
13cholesterol bindingGO:00154859.9APOA1, APOC3, APOE, CETP
14lipid transporter activityGO:00053199.9APOA1, APOB, APOE, CETP
15lipid bindingGO:00082898.7APOA1, APOB, APOC3, APOE, CETP, PLTP
16phospholipid bindingGO:00055438.6APOA1, APOB, APOC3, APOE, PLA2G7, PON1

Sources for Lipoprotein Lipase Deficiency

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet