MCID: LST001
MIFTS: 53

Listeriosis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Listeriosis

Aliases & Descriptions for Listeriosis:

Name: Listeriosis 12 56 52 3 42 14 69
Listeria Infection 12 50
Infection by Listeria Monocytogenes 12
Listeria Infections 41

Characteristics:

Orphanet epidemiological data:

56
listeriosis
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe),1-9/1000000 (Worldwide),1-9/1000000 (United States); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 56  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:11573
ICD10 33 A32 A32.9
ICD9CM 35 027.0
MeSH 42 D008088
NCIt 47 C82994
Orphanet 56 ORPHA533
MESH via Orphanet 43 D008088
UMLS via Orphanet 70 C0023860
ICD10 via Orphanet 34 A32.0 A32.1 A32.7 more
UMLS 69 C0023860

Summaries for Listeriosis

MedlinePlus : 41 listeriosis is a foodborne illness caused by listeria monocytogenes, bacteria found in soil and water. it can be in a variety of raw foods as well as in processed foods and foods made from unpasteurized milk. listeria is unlike many other germs because it can grow even in the cold temperature of the refrigerator. symptoms include fever and chills, headache, upset stomach and vomiting. treatment is with antibiotics. anyone can get the illness. but it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems. to reduce your risk use precooked and ready-to-eat foods as soon as you can avoid raw milk and raw milk products heat ready-to-eat foods and leftovers until they are steaming hot wash fresh fruits and vegetables avoid rare meat and refrigerated smoked seafood centers for disease control and prevention

MalaCards based summary : Listeriosis, also known as listeria infection, is related to hepatitis and tularemia, and has symptoms including nausea, vomiting and diarrhea. An important gene associated with Listeriosis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are PAK Pathway and Allograft rejection. The drugs Histamine and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include brain, t cells and liver, and related phenotypes are homeostasis/metabolism and immune system

Disease Ontology : 12 A primary bacterial infectious disease that results_in infection, has material basis in Listeria monocytogenes, which is transmitted_by ingestion of contaminated food or raw milk or transmitted_by congenital method. Ingestion of Listeria by pregnant women has symptom nausea, has symptom vomiting, has symptom diarrhea, has symptom fever, has symptom malaise, has symptom back pain, and has symptom headache. Maternal infection with Listeria can result in chorioamnionitis, premature labor, spontaneous abortion, or stillbirth.

CDC : 3 Multistate Outbreak of Listeriosis Linked to Soft Raw Milk Cheese Made by Vulto Creamery

Wikipedia : 71 Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes, although L.... more...

Related Diseases for Listeriosis

Diseases related to Listeriosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)
id Related Disease Score Top Affiliating Genes
1 hepatitis 30.0 IL10 IL6 TNF
2 tularemia 29.4 CD4 CD8A IL10 TNF
3 tuberculosis 28.9 CD4 CD8A IL10 IL6 TNF
4 pyridoxal 5'-phosphate-dependent epilepsy 10.3 IL10 TNF
5 tau syndrome 10.3 PRF1 TNF
6 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.3 IL6 TNF
7 tubular renal disease-cardiomyopathy syndrome 10.3 IL10 TNF
8 dyslexia 5 10.2 IL6 TNF
9 lagophthalmos 10.2 IL10 TNF
10 aortic atherosclerosis 10.2 IL6 TNF
11 steatitis 10.2 CD8A TNF
12 degenerative disc disease 10.2 IL6 TNF
13 tarsal tunnel syndrome 10.2 IDO1 IL10 TNF
14 chronic apical periodontitis 10.2 IDO1 IL10 TNF
15 multiple vertebral anomalies unusual facies 10.2 IL10 TNF
16 conidiobolomycosis 10.2 IL10 TNF
17 peripheral artery disease 10.2 IL10 MBL2 TNF
18 hyperoxaluria, primary, type ii 10.2 CD8A TNF
19 unilateral multicystic dysplastic kidney 10.2 IL6 TNF
20 childhood type dermatomyositis 10.2 IL6 MBL2 TNF
21 ureter inverted papilloma 10.2 IL10 IL6
22 pseudo-meigs syndrome 10.2 CDH1 IL10 TNF
23 cyclosporiasis 10.2 IL10 IL6 TNF
24 trichomalacia 10.2 IL10 IL6 TNF
25 conduct disorder 10.2 IL10 IL6 TNF
26 gastric dilatation 10.2 IL10 IL6 TNF
27 pancreatic signet ring cell adenocarcinoma 10.2 IL10 IL6 TNF
28 gonococcal endophthalmia 10.2 IL10 IL6 TNF
29 ectodermal dysplasia bartalos type 10.2 IL10 IL6 TNF
30 primary ciliary dyskinesia 10.2 IL10 IL6 TNF
31 hereditary alpha tryptasemia syndrome 10.2 IL10 IL6 TNF
32 autosomal recessive type iv ehlers-danlos syndrome 10.2 IL10 IL6 TNF
33 cole-carpenter syndrome 1 10.2 CDH1 IL10 TNF
34 bladder signet ring cell adenocarcinoma 10.2 IL10 IL6 TNF
35 erb-duchenne and dejerine-klumpke palsies 10.2 IL10 IL6 TNF
36 plummer's disease 10.2 IL10 IL6 TNF
37 orbital osteomyelitis 10.2 IL10 IL6 TNF
38 central nervous system lymphoma 10.2 IL10 IL6 TNF
39 labyrinthitis 10.2 IL10 IL6 TNF
40 disease of mental health 10.2 IL10 IL6 TNF
41 atrophy of prostate 10.1 IL10 IL6 TNF
42 follicular adenoma 10.1 IL10 IL6 TNF
43 immunoglobulin g deficiency 10.1 IL10 IL6 TNF
44 myiasis 10.1 IL10 IL6 TNF
45 alcoholic hepatitis 10.1 IL10 IL6 TNF
46 chordoid meningioma 10.1 IL10 IL6 TNF
47 periarthritis 10.1 IL10 MBL2 TNF
48 choroiditis 10.1 IL10 IL6 TNF
49 depressed scar 10.1 IL10 IL6 TNF
50 mansonelliasis 10.1 IL10 IL6 TNF

Comorbidity relations with Listeriosis via Phenotypic Disease Network (PDN):


Acute Cystitis Deficiency Anemia
Heart Disease

Graphical network of the top 20 diseases related to Listeriosis:



Diseases related to Listeriosis

Symptoms & Phenotypes for Listeriosis

Symptoms:

12
  • nausea
  • vomiting
  • diarrhea
  • fever
  • malaise
  • back pain
  • headache

UMLS symptoms related to Listeriosis:


fever, pruritus

MGI Mouse Phenotypes related to Listeriosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.96 ACTA1 CD4 CDH1 IDO1 IL10 IL6
2 immune system MP:0005387 9.81 CD4 CD8A CDH1 IDO1 IL10 IL6
3 integument MP:0010771 9.61 TNF CD4 CD8A CDH1 IL10 IL6
4 liver/biliary system MP:0005370 9.1 ACTA1 IL10 IL6 LIPI PRF1 TNF

Drugs & Therapeutics for Listeriosis

Drugs for Listeriosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Histamine Approved, Investigational Phase 2 75614-87-8, 51-45-6 774
2 Vaccines Phase 2
3 Anti-Bacterial Agents Phase 2
4 Anti-Infective Agents Phase 2
5
Histamine Phosphate Phase 2 51-74-1 65513
6 Neurotransmitter Agents Phase 2
7 Histamine Antagonists Phase 2
8 Histamine H1 Antagonists Phase 2
9 Antibiotics, Antitubercular Phase 2
10 Antitubercular Agents Phase 2
11
Amoxicillin Approved, Vet_approved 26787-78-0 33613 2171

Interventional clinical trials:


id Name Status NCT ID Phase
1 ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer Recruiting NCT02002182 Phase 2
2 An Assessment of an Attenuated Live Listeria Vaccine in CIN 2+ Terminated NCT01116245 Phase 2
3 Study of Safety and Tolerability of Multiple Intravenous Doses of ANZ-521 in Adults With Chronic Hepatitis C Virus Terminated NCT00800007 Phase 1, Phase 2
4 National Study on Listeriosis and Listeria Recruiting NCT01520597
5 Neurological Consequences of Perinatal Listeriosis Infection Recruiting NCT02580812
6 Incidence, Risk Factors and Impact on Renal Function of the Appearance of Crystalluria Under High-dose Intravenous Amoxicillin Recruiting NCT02853292
7 Genetic Susceptibility and Biomarkers in Listeriosis (MONALISA-GENBIO) Enrolling by invitation NCT02924220

Search NIH Clinical Center for Listeriosis

Cochrane evidence based reviews: listeriosis

Genetic Tests for Listeriosis

Anatomical Context for Listeriosis

MalaCards organs/tissues related to Listeriosis:

39
Brain, T Cells, Liver, Neutrophil, Bone, Bone Marrow, Placenta

Publications for Listeriosis

Articles related to Listeriosis:

(show top 50) (show all 595)
id Title Authors Year
1
Hospital-acquired listeriosis linked to a persistently contaminated milkshake machine. ( 28065212 )
2017
2
Oral exposure to Listeria monocytogenes in aged IL-17RKO mice: A possible murine model to study listeriosis in susceptible populations. ( 27574777 )
2016
3
A rare case of listeriosis, acute cholecystitis and multiple myeloma. ( 27170703 )
2016
4
Genome Sequences of Listeria monocytogenes Strains Responsible for Cheese- and Cooked Ham Product-Associated Swiss Listeriosis Outbreaks in 2005 and 2011. ( 26966206 )
2016
5
Fresh Produce-Associated Listeriosis Outbreaks, Sources of Concern, Teachable Moments, and Insights. ( 26818997 )
2016
6
Older Adult Consumer Knowledge, Attitudes, and Self-Reported Storage Practices of Ready-to-Eat Food Products and Risks Associated with Listeriosis. ( 26818987 )
2016
7
Listeriosis and Toxoplasmosis in Pregnancy: Essentials for Healthcare Providers. ( 27104604 )
2016
8
Notes from the Field: Outbreak of Listeriosis Associated with Consumption of Packaged Salad - United States and Canada, 2015-2016. ( 27559935 )
2016
9
How older people store and use food could increase listeriosis risk. ( 27682379 )
2016
10
Molecular Typing and Epidemiology of Human Listeriosis Cases, Denmark, 2002-2012(1). ( 26982714 )
2016
11
Recovery and Growth Potential of Listeria monocytogenes in Temperature Abused Milkshakes Prepared from Naturally Contaminated Ice Cream Linked to a Listeriosis Outbreak. ( 27242775 )
2016
12
Neonatal listeriosis in the UK 2004-2014. ( 27867063 )
2016
13
Whole-genome Sequencing Used to Investigate a Nationwide Outbreak of Listeriosis Caused by Ready-to-eat Delicatessen Meat, Denmark, 2014. ( 27025820 )
2016
14
An Outbreak of Human Listeriosis in England between 2010 and 2012 Associated with the Consumption of Pork Pies. ( 27296419 )
2016
15
How can patients and their physicians contribute to an outbreak investigation? Experiences from a nationwide listeriosis outbreak in Switzerland. ( 27878798 )
2016
16
Risk Assessment of Human Listeriosis from Semisoft Cheeses Made from Raw Sheep's Milk in Lazio and Tuscany (Italy). ( 27285819 )
2016
17
Older adults' domestic kitchen practices associated with an increased risk of listeriosis. ( 27354500 )
2016
18
Correction: Risk Factors for Sporadic Non-Pregnancy Associated Listeriosis in Germany-Immunocompromised Patients and Frequently Consumed Ready-To-Eat Products. ( 27788259 )
2016
19
Use of Whole Genome Sequencing and Patient Interviews To Link a Case of Sporadic Listeriosis to Consumption of Prepackaged Lettuce. ( 27296429 )
2016
20
Reductions in neonatal listeriosis: "Collateral benefit" of Group B streptococcal prophylaxis? ( 26772166 )
2016
21
Clinical, Laboratory, and Placental Findings in Perinatal Listeriosis. ( 27212240 )
2016
22
Trends in US Hospital Stays for Listeriosis in Infants. ( 26980754 )
2016
23
Listeriosis downregulates hepatic cytochrome P450 enzymes in sublethal murine infection. ( 27273978 )
2016
24
Comparing listeriosis risks in at-risk populations using a user-friendly quantitative microbial risk assessment tool and epidemiological data. ( 27019157 )
2016
25
Enteric listeriosis in grazing steers supplemented with spoiled silage. ( 26699524 )
2016
26
Biomarker Tools to Design Clinical Vaccines Determined from a Study of Annual Listeriosis Incidence in Northern Spain. ( 27965668 )
2016
27
Whole Genome Sequence Analysis Using JSpecies Tool Establishes Clonal Relationships between Listeria monocytogenes Strains from Epidemiologically Unrelated Listeriosis Outbreaks. ( 26950338 )
2016
28
Neonatal listeriosis: Uncommon orA misdiagnosed? ( 27589546 )
2016
29
Draft Genome Sequences of Two Historical Listeria monocytogenes Strains from Human Listeriosis Cases in 1933. ( 27932656 )
2016
30
Letter to the editor of infection in response to de Francesco et al., a cluster of invasive listeriosis in Brescia, Italy. ( 27506566 )
2016
31
Enrichment dynamics of Listeria monocytogenes and the associated microbiome from naturally contaminated ice cream linked to a listeriosis outbreak. ( 27852235 )
2016
32
Implementation of Nationwide Real-time Whole-genome Sequencing to Enhance Listeriosis Outbreak Detection and Investigation. ( 27090985 )
2016
33
Ongoing outbreak of invasive listeriosis due to serotype 1/2a Listeria monocytogenes, Ancona province, Italy, January 2015 to February 2016. ( 27168589 )
2016
34
Listeriosis: Is It a Rare Disease in Thailand? ( 27249907 )
2016
35
Assessment of the Incubation Period for Invasive Listeriosis. ( 27535950 )
2016
36
Factors influencing the time between onset of illness and specimen collection in the diagnosis of non-pregnancy associated listeriosis in England and Wales. ( 27341796 )
2016
37
Use of proton pump inhibitors and the risk of listeriosis. A nationwide registry-based case-control study. ( 28013257 )
2016
38
Systemic listeriosis following vaccination with the attenuated Listeria monocytogenes therapeutic vaccine, ADXS11-001. ( 26618528 )
2016
39
Comorbidities and factors associated with central nervous system infections and death in non-perinatal listeriosis: a clinical case series. ( 27267465 )
2016
40
Genome Sequence of Listeria monocytogenes Strain HPB5415, Collected during a 2008 Listeriosis Outbreak in Canada. ( 26067972 )
2015
41
It Is Not All about Single Nucleotide Polymorphisms: Comparison of Mobile Genetic Elements and Deletions in Listeria monocytogenes Genomes Links Cases of Hospital-Acquired Listeriosis to the Environmental Source. ( 26311854 )
2015
42
Pregnancy - associated human listeriosis: Virulence and genotypic analysis of Listeria monocytogenes from clinical samples. ( 26231373 )
2015
43
Protective dendritic cell responses against listeriosis induced by the short form of the deubiquitinating enzyme CYLD are inhibited by full-length CYLD. ( 25675948 )
2015
44
Multi-Province Listeriosis Outbreak Linked to Contaminated Deli Meat Consumed Primarily in Institutional Settings, Canada, 2008. ( 26258258 )
2015
45
A cluster of invasive listeriosis in Brescia, Italy. ( 25687587 )
2015
46
Multistate outbreak of listeriosis caused by imported cheese and evidence of cross-contamination of other cheeses, USA, 2012. ( 26122394 )
2015
47
Molecular epidemiology and genetic diversity of Listeria monocytogenes isolates from a wide variety of ready-to-eat foods and their relationship to clinical strains from listeriosis outbreaks in Chile. ( 25983727 )
2015
48
Efficacy of cell wall deficient spheroplasts against experimental murine listeriosis. ( 25833403 )
2015
49
Quantitative risk assessment of human salmonellosis and listeriosis related to the consumption of raw milk in Italy. ( 25581173 )
2015
50
Notes from the field: listeriosis associated with stone fruit - United States, 2014. ( 25789745 )
2015

Variations for Listeriosis

Expression for Listeriosis

Search GEO for disease gene expression data for Listeriosis.

Pathways for Listeriosis

Pathways related to Listeriosis according to GeneCards Suite gene sharing:

(show all 25)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.12 ACTA1 CD4 CDH1 IL10 IL6 TNF
2
Show member pathways
12.59 CD4 CD8A IL10 IL6 PRF1 TNF
3
Show member pathways
12.44 CD4 IL10 IL6 TNF
4
Show member pathways
12.43 CD4 IL10 IL6 TNF
5 12.36 CD8A IDO1 IL10 TNF
6
Show member pathways
12.24 CD4 CD8A IL10 IL6 TNF
7
Show member pathways
12 IL10 IL6 TNF
8 11.82 IL10 IL6 TNF
9
Show member pathways
11.79 CD4 CD8A PRF1
10
Show member pathways
11.79 CD4 IL10 IL6 TNF
11 11.72 IL10 IL6 TNF
12 11.72 CD4 CD8A IL10 IL6 TNF
13 11.69 CD4 CD8A IL6 TNF
14 11.6 IL10 IL6 TNF
15 11.56 IL10 IL6 TNF
16 11.53 CD4 CD8A IL10 TNF
17
Show member pathways
11.49 CD8A PRF1 TNF
18 11.38 IL10 IL6 TNF
19 11.36 IL10 IL6 TNF
20 11.2 IL10 IL6 TNF
21 11 IDO1 IL10 IL6 TNF
22 10.98 CD4 CD8A CDH1 IL10 IL6 TNF
23 10.97 IL6 TNF
24 10.9 IL6 TNF
25 10.73 CD4 IL10 IL6 TNF

GO Terms for Listeriosis

Cellular components related to Listeriosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CD8A CDH1 IL10 IL6 LIPI MBL2
2 T cell receptor complex GO:0042101 9.16 CD4 CD8A
3 external side of plasma membrane GO:0009897 8.92 CD4 CD8A IL6 TNF

Biological processes related to Listeriosis according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.91 CD4 CDH1 IL10 IL6 TNF
2 immune response GO:0006955 9.8 CD4 CD8A IL10 IL6 TNF
3 cellular response to lipopolysaccharide GO:0071222 9.76 IL10 IL6 TNF
4 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.72 IL10 IL6 TNF
5 response to organic substance GO:0010033 9.71 CDH1 IL10 TNF
6 response to glucocorticoid GO:0051384 9.65 IL10 IL6 TNF
7 defense response to Gram-positive bacterium GO:0050830 9.61 IL6 MBL2 TNF
8 defense response to protozoan GO:0042832 9.6 IL10 IL6
9 positive regulation of calcium-mediated signaling GO:0050850 9.59 CD4 CD8A
10 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.58 IL10 TNF
11 positive regulation of chemokine production GO:0032722 9.57 IL6 TNF
12 cellular response to hepatocyte growth factor stimulus GO:0035729 9.56 IL10 IL6
13 inflammatory response GO:0006954 9.55 IDO1 IL10 IL6 LXN TNF
14 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.52 IL10 TNF
15 negative regulation of lipid storage GO:0010888 9.49 IL6 TNF
16 endothelial cell apoptotic process GO:0072577 9.46 IL10 TNF
17 T cell activation GO:0042110 9.43 CD4 CD8A IL6
18 negative regulation of cytokine secretion involved in immune response GO:0002740 9.37 IL10 TNF
19 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.32 IL6 TNF
20 receptor biosynthetic process GO:0032800 8.96 IL10 TNF
21 negative regulation of growth of symbiont in host GO:0044130 8.8 IL10 MBL2 TNF

Sources for Listeriosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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