MCID: LST001
MIFTS: 57

Listeriosis malady

Rare diseases, Infectious diseases categories
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Summaries for Listeriosis

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Sources:
8Disease Ontology, 34MedlinePlus, 4CDC, 65Wikipedia, 33MalaCards
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MedlinePlus:34 Listeriosis is a foodborne illness caused by listeria monocytogenes, bacteria found in soil and water. it can be in a variety of raw foods as well as in processed foods and foods made from unpasteurized milk. listeria is unlike many other germs because it can grow even in the cold temperature of the refrigerator. symptoms include fever and chills, headache, upset stomach and vomiting. treatment is with antibiotics. anyone can get the illness. but it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems. to reduce your risk use precooked and ready-to-eat foods as soon as you can avoid raw milk and raw milk products heat ready-to-eat foods and leftovers until they are steaming hot wash fresh fruits and vegetables avoid rare meat and refrigerated smoked seafood centers for disease control and prevention

MalaCards: Listeriosis, also known as listeria infection, is related to toxoplasmosis and systemic lupus erythematosus, and has symptoms including back pain, malaise and diarrhea. An important gene associated with Listeriosis is ACTA1 (actin, alpha 1, skeletal muscle), and among its related pathways are MSP-RON Signaling and Apoptosis and survival Caspase cascade. The compounds mannan and indoleamine have been mentioned in the context of this disorder. Affiliated tissues include brain, t cells and liver, and related mouse phenotypes are homeostasis/metabolism and immune system.

Disease Ontology:8 A primary bacterial infectious disease that results in infection, has material basis in listeria monocytogenes, which is transmitted by ingestion of contaminated food or raw milk or transmitted by congenital method. ingestion of listeria by pregnant women has symptom nausea, has symptom vomiting, has symptom diarrhea, has symptom fever, has symptom malaise, has symptom back pain, and has symptom headache. maternal infection with listeria can result in chorioamnionitis, premature labor, spontaneous abortion, or stillbirth.

CDC:4 Listeriosis, a serious infection usually caused by eating food contaminated with the bacterium Listeria monocytogenes, is an important public health problem in the United States. The disease primarily affects older adults, pregnant women, newborns, and adults with weakened immune systems. However, rarely, persons without these risk factors can also be affected. The risk may be reduced by recommendations for safe food preparation, consumption, and storage.

Wikipedia:65 Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes, although L.... more...

Aliases & Classifications for Listeriosis

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8Disease Ontology, 10DISEASES, 45Novoseek, 49Orphanet, 62UMLS, 43NIH Rare Diseases, 34MedlinePlus, 27ICD9CM, 58SNOMED-CT, 35MeSH, 40NCIt, 26ICD10 via Orphanet, 36MESH via Orphanet, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


Characteristics (Orphanet epidemiological data):

49
listeriosis:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

listeriosis 8 10 45 49 62
listeria infection 8 43
infection due to listeria monocytogenes 8
infection by listeria monocytogenes 8
listeriosis, unspecified 8
listeria infections 34
listeriosis nos 8


External Ids:

Disease Ontology8 DOID:11573
ICD9CM27 027.0
MeSH35 D008088
NCIt40 C82994
ICD10 via Orphanet26 A32.7, A32.0, A32.1 A32.8, A32.9, more
MESH via Orphanet36 D008088
SNOMED-CT via Orphanet59 4241002
UMLS via Orphanet63 C0023860
ICD1025 A32, A32.9

Related Diseases for Listeriosis

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17GeneCards, 18GeneDecks
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Diseases related to Listeriosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1toxoplasmosis30.4CD4
2systemic lupus erythematosus30.4TNF, MBL2, CD4
3respiratory failure30.2ACTA1, TNF
4connective tissue disease30.1TNF, CD4
5leukemia30.1IDO1, TNF, MBL2, CD4
6meningitis30.0SUMF2, MBL2, CD4
7encephalitis29.9CD4, IDO1
8aspergillosis29.9CD4, MBL2
9tuberculosis29.8TNF, MBL2, CD4
10multiple sclerosis29.8IDO1, TNF, MBL2, CD4
11prosthetic joint infection10.4
12lupus erythematosus10.3
13cerebritis10.3
14tularemia10.2
15gastroenteritis10.2
16hepatitis10.2
17shigellosis10.1
18chronic lymphocytic leukemia10.1
19cryptococcosis10.1CD4
20mycobacterium avium complex disease10.1CD4
21sialadenitis10.1CD4
22histoplasmosis10.1CD4
23leprosy10.1CD4
24leishmaniasis10.1CD4
25secondary syphilis10.1
26syphilis10.1
27skin disease10.1CD4
28behcet's disease10.0MBL2, TNF
29encephalomyelitis10.0IDO1, TNF
30malaria10.0CD4, TNF
31vasculitis10.0TNF, MBL2
32interstitial lung disease10.0CD4, TNF
33toxic shock syndrome10.0TNF, CD4
34septic shock10.0TNF, MBL2
35cryptosporidiosis10.0MBL2, CD4
36periodontal disease10.0TNF, CD4
37uveitis10.0TNF, CD4
38synovitis10.0CD4, TNF
39thyroiditis10.0MBL2, CD4
40diarrhea10.0CD4, SUMF2
41sepsis10.0IDO1, TNF, MBL2
42hepatitis c10.0TNF, IDO1
43hypersensitivity reaction type ii disease10.0TNF, CD4
44eosinophilia10.0MBL2, CD4
45atherosclerosis10.0MBL2, TNF, IDO1
46primary hyperoxaluria10.0CD4, TNF
47allergic rhinitis10.0CD4, MBL2
48arthritis10.0IDO1, TNF, CD4
49influenza10.0CD4, MBL2, IDO1
50sarcoidosis10.0CD4, TNF

Graphical network of the top 20 diseases related to Listeriosis:



Diseases related to listeriosis

Symptoms for Listeriosis

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Sources:
8Disease Ontology
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Symptoms:

8 (show all 7)
  • back pain
  • malaise
  • diarrhea
  • vomiting
  • nausea
  • headache
  • fever

Drugs & Therapeutics for Listeriosis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Listeriosis

Search NIH Clinical Center for Listeriosis

Genetic Tests for Listeriosis

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Anatomical Context for Listeriosis

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33MalaCards
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MalaCards organs/tissues related to Listeriosis:

33
Brain, T cells, Liver, Bone, Bone marrow, Placenta, Spleen, Heart, Testes, Monocytes, Pituitary, Nk cells

Animal Models for Listeriosis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Listeriosis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.4IDO1, TNF, ACTA1, MBL2, CD4
2MP:00053877.6IDO1, TNF, BAHD1, MBL2, CD4

Publications for Listeriosis

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Sources:
52PubMed
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Articles related to Listeriosis:

(show top 50)    (show all 493)
idTitleAuthorsYear
1
Probable nosocomial transmission of listeriosis in neonates. (24001996)
2013
2
Listeriosis infection of an abdominal aortic aneurysm in a diabetic patient. (23599616)
2013
3
Listeriosis: not only during pregnancy. (24298598)
2013
4
Severe invasive listeriosis--case report. (23272533)
2012
5
A complicated case of cholecystitis, listeriosis and HIV/AIDS. (22715268)
2011
6
Listeriosis: a resurgent foodborne infection. (20002687)
2010
7
Substantial increase in listeriosis, Denmark 2009. (20350498)
2010
8
The increasing prevalence of listeriosis--what are we missing? (20042433)
2010
9
Listeriosis probe identifies multiple deficiencies. (19720701)
2009
10
Epidemiology of listeriosis in Austria. (19280136)
2009
11
Listeriosis in pregnancy complicated by postpartum heart block. (19622946)
2009
12
Listeriosis: a primer. (18787096)
2008
13
Listeriosis in Norway 1977-2003. (17464861)
2007
14
TNF is important for pathogen control and limits brain damage in murine cerebral listeriosis. (16951360)
2006
15
Listeria monocytogenes food monitoring data and incidence of human listeriosis in Hungary, 2004. (16934896)
2006
16
Cerebral listeriosis in an adult Freiberger gelding. (16542674)
2006
17
Canadian listeriosis reference service. (16602988)
2006
18
Listeriosis in Portugal: an existing but under reported infection. (17054782)
2006
19
Molecular characterization of Listeria monocytogenes strains associated with outbreaks of listeriosis in humans and ruminants and food products by serotyping and automated ribotyping. (16244967)
2005
20
An outbreak of food-borne listeriosis due to cheese in Japan, during 2001. (15979181)
2005
21
Brainstem and cranial nerve abnormalities: listeriosis, otitis media/interna, and pituitary abscess syndrome. (15203225)
2004
22
Respiratory failure due to pharyngeal dysfunction: a singular presentation of brainstem listeriosis. (12528037)
2003
23
Pathogen, host and environmental factors contributing to the pathogenesis of listeriosis. (12827280)
2003
24
Listeriosis in a free-ranging colobus monkey (Colobus guereza caudatus) in Kenya. (12585602)
2003
25
The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis. (11907101)
2002
26
Listeriosis in recipients of allogeneic blood and marrow transplantation: thirteen year review of disease characteristics, treatment outcomes and a new association with human cytomegalovirus infection. (12080357)
2002
27
Clinical findings and treatment of listeriosis in 67 sheep and goats. (11829065)
2002
28
Listeriosis: an emerging food-borne disease. (11517630)
2001
29
Dietitians can prevent listeriosis. (11269602)
2001
30
Evaluation of Caesalpinia ferrea extract on bone marrow hematopoiesis in the murine models of listeriosis and Ehrlich ascites tumor. (11694028)
2001
31
Does administration of infliximab increase susceptibility to listeriosis? (10710107)
2000
32
Listeriosis, France. (10734782)
2000
33
Cytotoxic T-cell, delayed type hypersensitive and listeriolysin O responses in experimental bovine listeriosis. (10063538)
1999
34
Roles for tumor necrosis factor and gamma interferon in resistance to enteric listeriosis. (9573134)
1998
35
Kinetics of interferon-gamma production and its comparison with anti-listeriolysin O detection in experimental bovine listeriosis. (10066124)
1998
36
Immunohistopathological findings in an adult llama with listeriosis. (9829307)
1998
37
Management of listeriosis. (9105758)
1997
38
Foodborne listeriosis. (9282388)
1997
39
An outbreak of listeriosis in a breeding colony of chinchillas. (9249176)
1997
40
Animal and human listeriosis: a shared problem? (9125351)
1997
41
Food poisoning, listeriosis, and febrile gastroenteritis. (9155220)
1997
42
A 10 year survey of the epidemiology and clinical aspects of listeriosis in a provincial English city. (7963642)
1994
43
Verification of causal relationships between Listeria monocytogenes isolates implicated in food-borne outbreaks of listeriosis by randomly amplified polymorphic DNA patterns. (8051257)
1994
44
Endogenous IL-1 is required for neutrophil recruitment and macrophage activation during murine listeriosis. (8051414)
1994
45
Clinical presentation and outcome in cases of listeriosis. (8353241)
1993
46
Gastrointestinal carriage of Listeria monocytogenes in household contacts of patients with listeriosis. (8486970)
1993
47
Listeriosis epidemic. (8102730)
1993
48
Fetal listeriosis during the second trimester of gestation. (1437878)
1992
49
Listeriosis in France. (1285236)
1992
50
Listeriosis--a puzzling disease. (1428186)
1992

Variations for Listeriosis

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Expression for genes affiliated with Listeriosis

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Listeriosis

Search GEO for disease gene expression data for Listeriosis.

Pathways for genes affiliated with Listeriosis

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Sources:
50PathCards, 53QIAGEN, 60Thomson Reuters, 55Reactome, 38NCBI BioSystems Database, 30KEGG, 54R&D Systems
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Pathways related to Listeriosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6ACTA1, TNF
2
Show member pathways
FAS pathway and Stress induction of HSP regulation38
Apoptosis and survival FAS signaling cascades60
Caspase cascade in apoptosis38
9.6ACTA1, TNF
39.6IDO1, TNF
49.5CD4, TNF
5
Show member pathways
IL27-mediated signaling events38
9.5TNF, CD4
69.5CD4, TNF
7
Show member pathways
9.2TNF, ACTA1, CD4
8
Show member pathways
9.2ACTA1, CD4, TNF
9
Show member pathways
Apoptosis and survival TNFR1 signaling pathway60
TWEAK Signaling Pathway38
Apoptosis Modulation by HSP7038
HIV-1 Nef- Negative effector of Fas and TNF-alpha38
9.2CD4, ACTA1, TNF

Compounds for genes affiliated with Listeriosis

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Sources:
45Novoseek, 51PharmGKB, 11DrugBank, 29IUPHAR, 3BitterDB, 24HMDB
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Compounds related to Listeriosis according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1mannan459.9CD4, MBL2
2indoleamine459.9IDO1, TNF
3zymosan459.9TNF, MBL2
42,5-oligoadenylate459.9TNF, IDO1
5polymyxin b459.8MBL2, TNF
6poly(i-c)459.8TNF, IDO1
7lipoteichoic acid459.8TNF, MBL2
8l-nmma459.8TNF, IDO1
9infliximab45 51 1111.8TNF, IDO1
10tarc459.6CD4, TNF
11manganese superoxide459.6TNF, IDO1
12peptidoglycan45 2910.5MBL2, ACTA1, TNF
13lactacystin459.5CD4, TNF
14chloroquine45 3 51 29 1113.4TNF, CD4
15pge2459.3IDO1, TNF, CD4
16superoxide45 2410.3IDO1, TNF, MBL2
17cycloheximide459.1CD4, TNF, IDO1
18neopterin459.1CD4, MBL2, TNF, IDO1
19rantes459.1IDO1, TNF, MBL2, CD4
20lipid459.0TNF, ACTA1, MBL2, CD4
21serine458.4CD4, MBL2, ACTA1, TNF

GO Terms for genes affiliated with Listeriosis

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16Gene Ontology
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Biological processes related to Listeriosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to mechanical stimulusGO:0096129.6ACTA1, TNF
2negative regulation of growth of symbiont in hostGO:0441309.4MBL2, TNF
3defense response to Gram-positive bacteriumGO:0508309.2MBL2, TNF

Products for genes affiliated with Listeriosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Listeriosis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet