Summaries for Listeriosis

Sources:
6Disease Ontology, 23MedlinePlus, 2CDC, 44Wikipedia, 22MalaCards
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MedlinePlus: Listeriosis is a foodborne illness caused by listeria monocytogenes, bacteria found in soil and water. it can be in a variety of raw foods as well as in processed foods and foods made from unpasteurized milk. listeria is unlike many other germs because it can grow even in the cold temperature of the refrigerator. symptoms include fever and chills, headache, upset stomach and vomiting. anyone can get the illness. but it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems. to reduce your risk use precooked and ready-to-eat foods as soon as you can avoid raw milk and raw milk products heat ready-to-eat foods and leftovers until they are steaming hot wash fresh fruits and vegetables avoid rare meat and seafood centers for disease control and prevention23

MalaCards: Listeriosis, also known as listeria infection, is related to hepatitis c and immunodeficiency, and has symptoms including nausea, vomiting and diarrhea. An important gene associated with Listeriosis is ACTA1 (actin, alpha 1, skeletal muscle), and among its related pathways are Antigen processing and presentation and Immune System. The drugs amoxicillin and ampicillin sodium and the compounds 1-methyltryptophan and tocilizumab have been mentioned in the context of this disorder. Affiliated tissues include brain, and related mouse phenotypes are immune system and hematopoietic system.

Disease Ontology: A primary bacterial infectious disease that results in infection, has material basis in listeria monocytogenes, which is transmitted by ingestion of contaminated food or raw milk or transmitted by congenital method. ingestion of listeria by pregnant women has symptom nausea, has symptom vomiting, has symptom diarrhea, has symptom fever, has symptom malaise, has symptom back pain, and has symptom headache. maternal infection with listeria can result in chorioamnionitis, premature labor, spontaneous abortion, or stillbirth.6

CDC: Listeriosis, a serious infection usually caused by eating food contaminated with the bacterium Listeria monocytogenes, is an important public health problem in the United States. The disease primarily affects older adults, pregnant women, newborns, and adults with weakened immune systems. However, rarely, persons without these risk factors can also be affected. The risk may be reduced by recommendations for safe food preparation, consumption, and storage.2

Wikipedia: Listeriosis is a bacterial infection caused by a Gram-positive, motile bacterium, Listeria...44 more...

Aliases & Descriptions for Listeriosis

Sources:
2CDC, 6Disease Ontology, 8DISEASES, 32Novoseek , 43UMLS, 30NIH Rare Diseases, 23MedlinePlus, 40SNOMED-CT, 27NCIt, 24MeSH, 19ICD9CM
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Aliases & Descriptions:

listeriosis 6 8 32 43
listeria infection 6 30
infection due to listeria monocytogenes (disorder) 6
listeriosis, unspecified (disorder) 6
infection by listeria monocytogenes 6
listeriosis nos (disorder) 6
listeriosis (disorder) 6
listeria infections 23
infection 43

External Ids:

SNOMED-CT40 4241002, 186315001, 187320005 186320001, 406591006, more
ICD9CM19 027.0

Related Diseases for Listeriosis

Sources:
13GeneCards, 14GeneDecks
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Diseases related to listeriosis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 1461)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis c36.5IFNG, IDO1, TNF
2immunodeficiency33.3CD8A, CD4, IL6, MBL2, IFNG, IDO1
3hepatitis33.1KIR2DS4, CD8A, CD4, IL6, MBL2, IFNG
4cytomegalovirus infection32.2IL6, MBL2, IFNG, TNF, THY1
5hepatitis b30.8KIR2DS4, CD8A, CD4, IL6, MBL2, IFNG
6herpes simplex30.8CD8A, CD4, IL6, MBL2, IFNG, IDO1
7tuberculosis30.7CD8A, CD4, IL6, MBL2, IFNG, GLYR1
8influenza30.6CD8A, CD4, IL6, MBL2, IFNG, IDO1
9mycobacterial infection30.4IL6, MBL2, IFNG, TNF
10fibrosis30.0CD4, IL6, MBL2, IFNG, IDO1, TNF
11pneumonia29.9CD8A, CD4, IL6, MBL2, IFNG, IDO1
12intrauterine infections29.8IL6, IFNG, TNF
13cervicitis29.8KIR2DS4, CD4, IL6, MBL2, IFNG, IDO1
14hepatitis a29.7CD4, IFNG, TNF
15chronic active epstein-barr virus infection29.6IFNG, IDO1
16measles29.5CD8A, CD4, IL6, IFNG, IDO1, TNF
17chronic granulomatous disease29.4IFNG, IDO1, TNF
18vaccinia29.4CD8A, CD4, IFNG, IDO1, TNF
19sepsis29.4IL6, MBL2, IDO1, TNF
20cystic fibrosis29.3CD4, IL6, MBL2, IFNG, TNF, SUMF2
21kaposi's sarcoma29.2CD4, IL6, IFNG, TNF, ACTA1
22avian influenza29.1IL6, IFNG, TNF
23carcinoma29.0CD8A, CD4, IL6, MBL2, IFNG, IDO1
24duodenal ulcer29.0IL6, MBL2, TNF
25visceral leishmaniasis29.0MBL2, IFNG, TNF
26neutropenia28.9IL6, MBL2, IFNG, TNF
27hepatocellular carcinoma28.8CD8A, CD4, IL6, MBL2, IFNG, IDO1
28gastritis28.5KIR2DS4, CD4, IL6, MBL2, IFNG, TNF
29peptic ulcer28.5IL6, IFNG, TNF
30vaginitis28.5IL6, MBL2, IFNG, TNF
31campylobacteriosis28.4IFNG, SUMF2
32toxoplasmosis28.4CD4, IFNG, IDO1, TNF
33severe acute respiratory syndrome28.3CD4, IL6, MBL2, IFNG, TNF
34leukemia28.2KIR2DS4, CD8A, CD4, IL6, MBL2, IFNG
35systemic lupus erythematosus28.2CD4, IL6, MBL2, IFNG, TNF
36adult t-cell leukemia28.2IL6, IFNG, IDO1, TNF
37coccidioidomycosis28.1CD4, MBL2, IFNG
38encephalitis28.1CD8A, CD4, IL6, IFNG, IDO1, TNF
39acquired immunodeficiency syndrome28.0CD4, IL6, IFNG, TNF
40cervical carcinoma28.0CD4, IL6, IFNG, IDO1, TNF
41pulmonary tuberculosis28.0IL6, MBL2, IFNG, TNF
42cervical intraepithelial neoplasia27.8KIR2DS4, IL6, IFNG, TNF
43guillain-barre syndrome27.8MBL2, IFNG, TNF
44q fever27.8IL6, MBL2, IFNG, TNF
45bronchitis27.8CD4, IL6, IFNG, TNF
46viral hepatitis27.7IL6, MBL2, IFNG, TNF
47anemia27.7CD4, IL6, MBL2, IFNG, IDO1, TNF
48septic shock27.7IL6, MBL2, TNF
49atherosclerosis27.7CD4, IL6, MBL2, IFNG, IDO1, TNF
50osteomyelitis27.7IL6, IFNG, TNF, SUMF2

Graphical network of the top 20 diseases related to listeriosis:



Graphical network of diseases related to listeriosis

Clinical Features for Listeriosis

Sources:
6Disease Ontology
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Symptoms: nausea, vomiting, diarrhea, fever, malaise, back pain, headache.6

Drugs & Therapeutics for Listeriosis

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

Search CenterWatch for listeriosis

Drug clinical trials:

Search ClinicalTrials for listeriosis

Search NIH Clinical Center for listeriosis

Search CenterWatch for listeriosis

Inferred drug relations via UMLS/NDF-RT:

43 28 amoxicillin, amoxicillin trihydrate, ampicillin, ampicillin sodium, ampicillin trihydrate, bacampicillin, bacampicillin hydrochloride

Genetic Tests for Listeriosis

Anatomical Context for Listeriosis

Sources:
22MalaCards
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MalaCards organs/tissues related to listeriosis:

22
Brain

Phenotypes for genes affiliated with Listeriosis

Sources:
25MGI
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MGI Mouse Phenotypes related to listeriosis:

25
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1immune system phenotypeMP:00053876.7BAHD1, TNF, IFNG, MBL2, IL6, CD4
2hematopoietic system phenotypeMP:00053976.6IDO1, IFNG, MBL2, IL6, CD4, CD8A

Publications for genes affiliated with Listeriosis

Sources:
35PubMed
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Articles related to listeriosis:

idTitleAuthorsYearAffiliating Genes
1TNF is important for pathogen control and limits brain damage in murine cerebral listeriosis. (16951360)Virna S.... Schluter D.2006TNF
2Serodiagnosis of listeriosis based upon detection of antibodies against recombinant truncated forms of listeriolysin O. (8735086)Gholizadeh Y.... Gaillard J.L.1996MBL2

Expression for genes affiliated with Listeriosis

Sources:
1BioGPS
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Expression patterns in normal tissues for genes affiliated with Listeriosis

Pathways for genes affiliated with Listeriosis

Sources:
20KEGG, 38Reactome, 36QIAGEN, 41Thomson Reuters, 10EMD Millipore, 37R&D Systems
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Compounds for genes affiliated with Listeriosis

Sources:
32Novoseek , 9DrugBank, 18HMDB, 42Tocris Bioscience
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Compounds related to listeriosis according to GeneDecks:

(show all 45)
idCompoundScoreTop Affiliating Genes
11-methyltryptophan32 9.8IDO1, IFNG
2tocilizumab32 9.7TNF, IL6
3abatacept32 9 9 11.7IL6, TNF
4cdp57132 9.6IL6, TNF
53-hydroxyanthranilic acid32 18 10.6IDO1, IFNG
6interferon gamma32 9.4IFNG, TNF
7tenidap42 32 10.3IL6, TNF
8gabexate mesilate32 9.3IL6, TNF
9indoleamine32 9.3TNF, IDO1, IFNG
10lipoteichoic acid32 9.2TNF, MBL2, IL6
11anakinra32 9 9 11.2IL6, TNF
12l-nmma32 9.2IFNG, IDO1, TNF
13bucillamine32 9.2IFNG, IL6
14kynurenine32 9.1IFNG, IDO1
15peptidoglycan32 9.1ACTA1, TNF, MBL2, IL6
16vesnarinone32 8.9IL6, IFNG, TNF
17taurine chloramine32 8.9IL6, IFNG, TNF
18adalimumab32 9 9 10.9TNF, IFNG, IL6
19imiquimod32 42 9 9 11.9IL6, IFNG, TNF
20tarc32 8.9TNF, IFNG, CD4
21il-1232 8.9IL6, IFNG, TNF
22parthenolide32 8.9TNF, IFNG, IL6
23okt332 8.9TNF, IFNG, IL6
24gm-csf32 8.9TNF, IFNG, IL6
25triptolide32 8.9IL6, IFNG, TNF
26etanercept32 9 9 10.9TNF, IFNG, IL6
27polyinosinic-polycytidylic acid32 8.9TNF, IFNG, IL6
28ivig32 8.8IL6, IFNG, TNF
29ccl332 8.8TNF, IFNG, IL6
30pentoxifylline32 9 9 10.8TNF, IFNG, IL6
31thalidomide32 42 9 9 11.8IL6, IFNG, TNF
32melphalan32 9 9 10.7TNF, IFNG, IL6
332,5-oligoadenylate32 8.7TNF, IDO1, IFNG, IL6
34poly(i-c)32 8.7IL6, IFNG, IDO1, TNF
35infliximab32 9 9 10.7IL6, IFNG, IDO1, TNF
3615-deoxy-delta-12,14-prostaglandin j232 8.7IL6, IFNG, TNF
37pdtc32 8.6TNF, IFNG, IL6
38il 1032 8.5TNF, IFNG, IL6, CD8A
39polymyxin b32 8.5IL6, MBL2, IFNG, TNF
40prednisolone32 9 9 10.4IL6, MBL2, IFNG, TNF
41herbimycin a32 42 9.4CD4, IL6, IFNG, TNF
42pge232 8.1TNF, IDO1, IFNG, IL6, CD4
43cycloheximide32 7.9CD4, IL6, IFNG, IDO1, TNF
44neopterin32 7.8CD4, IL6, MBL2, IFNG, IDO1, TNF
45rantes32 7.7TNF, IDO1, IFNG, MBL2, IL6, CD4

GO Terms for genes affiliated with Listeriosis

Sources:
12Gene Ontology
See all sources

Cellular components related to listeriosis according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor complexGO:0421019.5CD8A, CD4
2external side of plasma membraneGO:0098977.6CD8A, CD4, IFNG, TNF, THY1

Biological processes related to listeriosis according to GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of vitamin D biosynthetic processGO:0605579.3IFNG, TNF
2acute-phase responseGO:0069539.3REG3G, IL6, MBL2
3positive regulation of calcidiol 1-monooxygenase activityGO:0605599.2TNF, IFNG
4negative regulation of lipid storageGO:0108889.2TNF, IL6
5positive regulation of membrane protein ectodomain proteolysisGO:0510449.1IFNG, TNF
6neutrophil apoptotic processGO:0017819.1IFNG, IL6
7defense response to Gram-positive bacteriumGO:0508309.1TNF, MBL2, IL6
8negative regulation of growth of symbiont in hostGO:0441308.9MBL2, IFNG, TNF
9positive regulation of chemokine biosynthetic processGO:0450808.8IFNG, TNF
10humoral immune responseGO:0069598.5IL6, IFNG, TNF

Sources for Listeriosis

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS