MCID: LST001
MIFTS: 56

Listeriosis malady

Infectious category

Summaries for Listeriosis

Sources:
8Disease Ontology, 34MedlinePlus, 3CDC, 64Wikipedia, 33MalaCards
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MedlinePlus:34 Listeriosis is a foodborne illness caused by listeria monocytogenes, bacteria found in soil and water. it can be in a variety of raw foods as well as in processed foods and foods made from unpasteurized milk. listeria is unlike many other germs because it can grow even in the cold temperature of the refrigerator. symptoms include fever and chills, headache, upset stomach and vomiting. treatment is with antibiotics. anyone can get the illness. but it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems. to reduce your risk use precooked and ready-to-eat foods as soon as you can avoid raw milk and raw milk products heat ready-to-eat foods and leftovers until they are steaming hot wash fresh fruits and vegetables avoid rare meat and refrigerated smoked seafood centers for disease control and prevention

MalaCards: Listeriosis, also known as listeria infection, is related to systemic lupus erythematosus and toxoplasmosis, and has symptoms including nausea, vomiting and diarrhea. An important gene associated with Listeriosis is IDO1 (indoleamine 2,3-dioxygenase 1), and among its related pathways are Cytokines and Inflammatory Response and Transcription Role of VDR in regulation of genes involved in osteoporosis. The compounds prednisolone and pge2 have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spleen and brain, and related mouse phenotypes are hematopoietic system and immune system.

Disease Ontology:8 A primary bacterial infectious disease that results in infection, has material basis in listeria monocytogenes, which is transmitted by ingestion of contaminated food or raw milk or transmitted by congenital method. ingestion of listeria by pregnant women has symptom nausea, has symptom vomiting, has symptom diarrhea, has symptom fever, has symptom malaise, has symptom back pain, and has symptom headache. maternal infection with listeria can result in chorioamnionitis, premature labor, spontaneous abortion, or stillbirth.

CDC:3 Listeriosis, a serious infection usually caused by eating food contaminated with the bacterium Listeria monocytogenes, is an important public health problem in the United States. The disease primarily affects older adults, pregnant women, newborns, and adults with weakened immune systems. However, rarely, persons without these risk factors can also be affected. The risk may be reduced by recommendations for safe food preparation, consumption, and storage.

Wikipedia:64 Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes, although L.... more...

Aliases & Classifications for Listeriosis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 49Orphanet, 61UMLS, 43NIH Rare Diseases, 34MedlinePlus, 57SNOMED-CT, 40NCIt, 27ICD9CM, 35MeSH, 36MESH via Orphanet, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Characteristics (Orphanet epidemiological data):

49
listeriosis:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

listeriosis 8 10 45 49 61
listeria infection 8 43
infection due to listeria monocytogenes 8
infection by listeria monocytogenes 8
listeriosis, unspecified 8
listeria infections 34
listeriosis nos 8


External Ids:

Disease Ontology8 DOID:11573
NCIt40 C82994
ICD9CM27 027.0
MeSH35 D008088
MESH via Orphanet36 D008088
ICD10 via Orphanet26 A32
SNOMED-CT via Orphanet58 4241002
UMLS via Orphanet62 C0023860
ICD1025 A32, A32.9

Related Diseases for Listeriosis

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Listeriosis:



Diseases related to listeriosis

Clinical Features for Listeriosis

Sources:
8Disease Ontology
See all sources


Symptoms:

8 (show all 7)
  • nausea
  • vomiting
  • diarrhea
  • fever
  • malaise
  • back pain
  • headache

Drugs & Therapeutics for Listeriosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Listeriosis

Drug clinical trials:

Search ClinicalTrials for Listeriosis

Search NIH Clinical Center for Listeriosis

Search CenterWatch for Listeriosis

Genetic Tests for Listeriosis

Anatomical Context for Listeriosis

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Listeriosis:

33
Bone marrow, Spleen, Brain, Heart, Small intestine, Liver, Placenta, Monocytes, Nk cells, T cells, B lymphoblasts, B cells, Fetal brain, Fetal liver, Pituitary

Animal Models for Listeriosis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Listeriosis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.2IFNG, MBL2, TNF, BATF3, CD4, CD8A
2MP:00053877.5IL6, IDO1, IFNG, MBL2, TNF, BAHD1

Publications for Listeriosis

Sources:
51PubMed
See all sources

Articles related to Listeriosis:

(show top 50)    (show all 500)
idTitleAuthorsYear
1
Challenges in listeriosis cluster and outbreak investigations, province of quebec, 1997-2011. (24134667)
2014
2
Molecular characterization of encephalitic bovine listeriosis from southern Brazil. (23832703)
2014
3
Probable nosocomial transmission of listeriosis in neonates. (24001996)
2013
4
Listeriosis infection of an abdominal aortic aneurysm in a diabetic patient. (23599616)
2013
5
Atypical cerebral listeriosis associated with Listeria innocua in a beef bull. (22898534)
2013
6
Listeriosis among elderly patients in Taiwan. (23819636)
2013
7
Subtyping of Listeria monocytogenes isolates recovered from retail ready-to-eat foods, processing plants and listeriosis patients in Sweden 2010. (23911759)
2013
8
Enhanced surveillance of invasive listeriosis in the Lombardy region, Italy, in the years 2006-2010 reveals major clones and an increase in serotype 1/2a. (23530941)
2013
9
Genetic determinants for cadmium and arsenic resistance among Listeria monocytogenes serotype 4b isolates from sporadic human listeriosis patients. (23377929)
2013
10
Epidemiology and risk management of listeriosis in India. (21955732)
2012
11
Pathology in practice. Encephalitic listeriosis. (22852568)
2012
12
Ether lipid vesicle-based antigens impart protection against experimental listeriosis. (22745536)
2012
13
Listeriosis outbreak in dairy cattle caused by an unusual Listeria monocytogenes serotype 4b strain. (21217050)
2011
14
Neonatal listeriosis: a case report from sub-Himalayas. (21304207)
2011
15
Microbiological and molecular investigation of an increase of human listeriosis in Belgium, 2006-2007. (20158978)
2010
16
Listeriosis in pregnancy. (20586347)
2010
17
Epidemiology of listeriosis in Austria. (19280136)
2009
18
Listeriosis remains a cause for concern in Europe. (19174430)
2009
19
Characterization of Listeria monocytogenes isolates from human listeriosis cases in Italy. (19605584)
2009
20
Increasing incidence of listeriosis in France and other European countries. (18439354)
2008
21
Brain stem encephalitis in listeriosis. (15849051)
2005
22
Brainstem and cranial nerve abnormalities: listeriosis, otitis media/interna, and pituitary abscess syndrome. (15203225)
2004
23
Encephalitic listeriosis in ruminants: immunohistochemistry as a diagnostic tool. (15610491)
2004
24
Listeriosis in the pregnant guinea pig: a model of vertical transmission. (14688130)
2004
25
Early-onset listeriosis in prematurity. (12845854)
2003
26
Listeriosis: therapeutic options. (12648838)
2003
27
Concomitant cytosolic delivery of two immunodominant listerial antigens by Salmonella enterica serovar typhimurium confers superior protection against murine listeriosis. (12438393)
2002
28
Evaluation of Caesalpinia ferrea extract on bone marrow hematopoiesis in the murine models of listeriosis and Ehrlich ascites tumor. (11694028)
2001
29
First report of an outbreak of ovine septicaemic listeriosis in Saudi Arabia. (11732420)
2001
30
Outbreak of listeriosis associated with homemade Mexican-style cheese--North Carolina, October 2000-January 2001. (11456331)
2001
31
Treatment of listeriosis. (10852095)
2000
32
Comparative investigations of Listeria monocytogenes isolated from a turkey processing plant, turkey products, and from human cases of listeriosis in Denmark. (11117953)
2000
33
Expression of E-selectin, P-selectin, and intercellular adhesion molecule-1 during experimental murine listeriosis. (10514421)
1999
34
Roles for tumor necrosis factor and gamma interferon in resistance to enteric listeriosis. (9573134)
1998
35
IL-4 secretion by CD4+ NK1+ T cells induces monocyte chemoattractant protein-1 in early listeriosis. (9200431)
1997
36
Effects of IL-13 on murine listeriosis. (9138006)
1997
37
Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response. (9314070)
1997
38
Typing Listeria monocytogenes isolates from fish products and human listeriosis cases. (9097430)
1997
39
Serodiagnosis of listeriosis based upon detection of antibodies against recombinant truncated forms of listeriolysin O. (8735086)
1996
40
Effect of immunomodulation with galactoside-specific mistletoe lectin on experimental listeriosis. (8837402)
1996
41
Occurrence of Listeria and listeriosis in Hungary. (9055453)
1996
42
Colony-stimulating factor 1 in the human response to neonatal listeriosis. (7890428)
1995
43
Effects of leflunomide on the course of listeriosis in mice. Short communication. (7612063)
1995
44
Listeriosis in a patient with long-term hemodialysis but without iron overload. (7753284)
1995
45
An epidemiological study of listeriosis complicating a bone marrow transplant. (8099929)
1993
46
Listeriosis in France. (1285236)
1992
47
Listeriosis in patients with chronic lymphocytic leukemia who were treated with fludarabine and prednisone. (1354425)
1992
48
Role of foods in sporadic listeriosis. I. Case-control study of dietary risk factors. The Listeria Study Group. (1552639)
1992
49
Magnetic resonance imaging in infections of the brain: findings in tuberculosis, listeriosis, toxoplasmosis, subacute sclerosing panencephalitis, and multiple sclerosis. (3455473)
1987
50
Periventricular leukomalacia and listeriosis in the newborn. (6007889)
1966

Genetic Variations for Listeriosis

Expression for genes affiliated with Listeriosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Listeriosis

Search GEO for disease gene expression data for Listeriosis.

Pathways for genes affiliated with Listeriosis

Sources:
38NCBI BioSystems Database, 12EMD Millipore, 52QIAGEN, 53R&D Systems, 30KEGG, 4Cell Signaling Technology, 54Reactome
See all sources

Pathways related to Listeriosis according to GeneCards/GeneDecks:

(show all 24)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2CD4
2
Transcription Role of VDR in regulation of genes involved in osteoporosis
Hide members
10.2IFNG
3
Hide members
10.0CD4, IFNG
4
Hide members
9.9IL6, CD4
59.9IL6, TNF
6
Hide members
9.7CD4, IFNG, CD8A
79.7IFNG, TNF, ACTA1
89.7CD8A, TNF, IFNG
9
Immune response Bacterial infections in normal airways
9.6IL6, TNF, IFNG
10
Hide members
9.6IFNG, TNF, IL6
119.6IFNG, TNF, IL6
129.6TNF, IL6, IFNG
139.6TNF, IL6, IFNG
149.6IL6, TNF, IFNG
15
Hide members
9.5BATF3, IFNG, TNF
169.4IFNG, IL6, TNF, IDO1
179.4IL6, TNF, CD4, CD8A
189.4THY1, IL6, TNF
19
Hide members
9.4CD4, IFNG, TNF, IL6
20
Development PDGF signaling via STATs and NF-kB
Hide members
9.4TNF, CD4, IL6, IFNG
219.2CD8A, CD4, THY1, IDO1
22
Hide members
9.1CD8A, CD4, IL6, TNF, IFNG
23
Hide members
9.1TNF, IFNG, IL6, CD8A, CD4
24
Hide members
8.8CD8A, CD4, MBL2, IL6, KLRG1, IFNG

Compounds for genes affiliated with Listeriosis

Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 24HMDB, 60Tocris Bioscience, 50PharmGKB, 2BitterDB
See all sources

Compounds related to Listeriosis according to GeneCards/GeneDecks:

(show all 49)
idCompoundScoreTop Affiliating Genes
1prednisolone45 29 1112.7MBL2
2pge24510.6CD4
3cycloheximide4510.5CD4
41-methyltryptophan4510.4IFNG, IDO1
5gm-csf45 2911.3IFNG, TNF
63-hydroxyanthranilic acid45 2411.3IFNG, IDO1
7tocilizumab45 1111.3IL6, TNF
8abatacept45 1111.3IL6, TNF
9cdp5714510.2TNF, IL6
10bucillamine4510.2IFNG, IL6
11interferon gamma4510.2TNF, IFNG
12anakinra45 1111.1TNF, IL6
13kynurenine4510.1IFNG, IDO1
14vesnarinone4510.1IFNG, IL6, TNF
15lipoteichoic acid4510.1MBL2, TNF, IL6
16l-nmma4510.1IFNG, TNF, IDO1
17taurine chloramine4510.1IL6, TNF, IFNG
18herbimycin a45 6011.0IFNG, TNF, CD4
19dexamethasone45 50 29 1113.0IL6, IDO1
20adalimumab45 50 1112.0TNF, IFNG, IL6
21il-124510.0TNF, IFNG, IL6
22imiquimod45 29 60 1113.0IFNG, TNF, IL6
23gabexate mesilate4510.0IL6, TNF
24okt34510.0IFNG, IL6, TNF
25triptolide4510.0IL6, TNF, IFNG
26parthenolide45 211.0TNF, IFNG, IL6
27polyinosinic-polycytidylic acid4510.0TNF, IFNG, IL6
28etanercept45 50 1112.0IL6, IFNG, TNF
29tarc4510.0TNF, IFNG, CD4
30ivig4510.0IL6, IFNG, TNF
31ccl345 2911.0IL6, TNF, IFNG
32melphalan45 1110.9IFNG, IL6, TNF
3315-deoxy-delta-12,14-prostaglandin j2459.9IL6, IFNG, TNF
34gold sodium thiomalate459.9IFNG, TNF
35mip 1alpha459.9TNF, IL6
36pdtc459.9IL6, TNF, IFNG
37peptidoglycan45 2910.9MBL2, ACTA1, IL6, TNF
38thalidomide45 50 60 1112.9TNF, IL6, IFNG
392,5-oligoadenylate459.9TNF, IL6, IFNG, IDO1
40poly(i-c)459.9IDO1, TNF, IL6, IFNG
41infliximab45 50 1111.8TNF, IL6, IFNG, IDO1
42polymyxin b459.8TNF, IFNG, MBL2, IL6
43lactacystin459.8CD4, TNF, IFNG
44il 10459.8IL6, IFNG, TNF, CD8A
45tuberculin459.7MBL2, IFNG
46neopterin459.4CD4, IL6, MBL2, IFNG, IDO1, TNF
47rantes459.4IDO1, IFNG, MBL2, TNF, CD4, IL6
48lipid458.6ACTA1, THY1, IL6, CD4, MBL2, TNF
49tyrosine458.3MBL2, IDO1, CD4, IL6, THY1, KIR2DS4

GO Terms for genes affiliated with Listeriosis

Sources:
16Gene Ontology
See all sources

Cellular components related to Listeriosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor complexGO:04210110.0CD8A, CD4
2external side of plasma membraneGO:0098978.3THY1, IL6, CD8A, CD4, TNF, IFNG

Biological processes related to Listeriosis according to GeneCards/GeneDecks:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of vitamin D biosynthetic processGO:06055710.2TNF, IFNG
2neutrophil apoptotic processGO:00178110.2IL6, IFNG
3positive regulation of calcidiol 1-monooxygenase activityGO:06055910.2TNF, IFNG
4epithelial cell proliferation involved in salivary gland morphogenesisGO:06066410.1TNF, IL6
5negative regulation of lipid storageGO:01088810.1IL6, TNF
6positive regulation of chemokine biosynthetic processGO:04508010.1IFNG, TNF
7negative regulation of growth of symbiont in hostGO:04413010.0IFNG, MBL2, TNF
8positive regulation of membrane protein ectodomain proteolysisGO:05104410.0TNF, IFNG
9positive regulation of nitric oxide biosynthetic processGO:0454299.9IL6, IFNG, TNF
10acute-phase responseGO:0069539.9MBL2, REG3G, IL6
11response to mechanical stimulusGO:0096129.9TNF, ACTA1, IL6
12positive regulation of chemokine productionGO:0327229.9TNF, IL6
13humoral immune responseGO:0069599.9TNF, IL6, IFNG
14positive regulation of osteoclast differentiationGO:0456729.8IFNG, TNF
15defense response to Gram-positive bacteriumGO:0508309.6TNF, IL6, REG3G, MBL2
16defense response to protozoanGO:0428329.6IFNG, IL6
17response to virusGO:0096159.5IFNG, BATF3, TNF
18inflammatory responseGO:0069549.3TNF, KLRG1, IL6, LXN

Products for genes affiliated with Listeriosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Listeriosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet