Lmna-related Dilated Cardiomyopathy malady

MalaCards: Lmna-related Dilated Cardiomyopathy, also known as cardiomyopathy, familial idiopathic, is related to familial hypertrophic cardiomyopathy and restrictive cardiomyopathy. An important gene associated with Lmna-related Dilated Cardiomyopathy is LMNA (lamin A/C).

OMIM: 115200

GeneReviews summary for dcm-lmna

lmna-related dilated cardiomyopathy 15 16 cardiomyopathy, familial idiopathic 43 idiopathic dilation cardiomyopathy 43 cardiomyopathy, dilated, 1a 33

dilated cardiomyopathy 1a 16 cardiomyopathies 43 cmd1a 16

Diseases related to lmna-related dilated cardiomyopathy by text searches and GeneDecks gene sharing:

(show top 50)    (show all 211)

id	Related Disease	Score	Top Affiliating Genes
1	familial hypertrophic cardiomyopathy	10.5
2	restrictive cardiomyopathy	9.1
3	arrhythmogenic right ventricular dysplasia	8.6
4	chagas disease	7.9
5	danon disease	7.9
6	stress cardiomyopathy	7.8
7	alcoholic cardiomyopathy	7.7
8	dilated cardiomyopathy with woolly hair and keratoderma	7.7
9	familial amyloid cardiomyopathy	7.7
10	familial restrictive cardiomyopathy	7.7
11	peripartum cardiomyopathy	7.7
12	naxos disease	7.2
13	aldosteronism	7.1
14	doxorubicin induced cardiomyopathy	7.1
15	mitochondrial cardiomyopathy	7.1
16	cardiomyopathy, dilated, 2a	7.0
17	abcc9-related dilated cardiomyopathy	7.0
18	eya4-related dilated cardiomyopathy	7.0
19	friedreich ataxia	7.0
20	myh7-related dilated cardiomyopathy	7.0
21	csrp3-related dilated cardiomyopathy	6.8
22	tnnt2-related dilated cardiomyopathy	6.8
23	tnnt2-related familial restrictive cardiomyopathy	6.8
24	dsg2-related dilated cardiomyopathy	6.8
25	vcl-related dilated cardiomyopathy	6.8
26	des-related dilated cardiomyopathy	6.8
27	fktn-related dilated cardiomyopathy	6.8
28	infantile histiocytoid cardiomyopathy	6.8
29	ldb3-related dilated cardiomyopathy	6.8
30	microcephaly-cardiomyopathy	6.8
31	myh6-related dilated cardiomyopathy	6.8
32	nexn-related dilated cardiomyopathy	6.8
33	pln-related dilated cardiomyopathy	6.8
34	rbm20-related dilated cardiomyopathy	6.8
35	scn5a-associated dilated cardiomyopathy	6.8
36	sgcd-related dilated cardiomyopathy	6.8
37	actn2-related dilated cardiomyopathy	6.8
38	tcap-related dilated cardiomyopathy	6.8
39	actc1-related dilated cardiomyopathy	6.6
40	cardiomyopathy and deafness due to trna lysine gene mutation	6.6
41	cardiomyopathy hypogonadism collagenoma syndrome	6.6
42	glycogen storage disease	6.6
43	psen1-related dilated cardiomyopathy	6.6
44	psen2-related dilated cardiomyopathy	6.6
45	sudden cardiac death multi-gene panels	6.6
46	tmpo-related dilated cardiomyopathy	6.6
47	hypertrophic cardiomyopathy	6.6
48	ventricular tachycardia	6.6
49	cardiomyopathy, familial hypertrophic, 7	6.5
50	cardiomyopathy, dilated, 1ff	6.5

Clinical features from OMIM: 115200

Approved drugs:

Drug clinical trials:

Genetic tests related to lmna-related dilated cardiomyopathy:

id	Genetic test	Affiliating Genes
1	Lmna-related Dilated Cardiomyopathy clinical/research	LMNA

Genes related to lmna-related dilated cardiomyopathy according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	LMNA	lamin A/C	11.0	Disorders