Aliases & Classifications for Lobular Neoplasia

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Lobular Neoplasia, Aliases & Descriptions:

Name: Lobular Neoplasia 9 11 60
Lobular Carcinoma in Situ of Breast 60
Non-Infiltrating Lobular Carcinoma 60
 
Lobular Intraepithelial Neoplasia 9
Lobular Carcinoma in Situ 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology9 DOID:3010
NCIt38 C27939
ICD1025 D05.0

Summaries for Lobular Neoplasia

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Wikipedia:63 Lobular neoplasia can refer to: more...

MalaCards based summary: Lobular Neoplasia, also known as lobular carcinoma in situ of breast, is related to breast fibroadenoma and ductal carcinoma in situ. An important gene associated with Lobular Neoplasia is LINS (lines homolog (Drosophila)), and among its related pathways are Ovarian Infertility Genes and Thyroid cancer. The compounds ly 117018 and 17alpha estradiol have been mentioned in the context of this disorder. Affiliated tissues include breast, and related mouse phenotypes are renal/urinary system and no phenotypic analysis.

Related Diseases for Lobular Neoplasia

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Diseases related to Lobular Neoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idRelated DiseaseScoreTop Affiliating Genes
1breast fibroadenoma31.1ESR1
2ductal carcinoma in situ31.0CDH1, ESR1
3breast cancer30.7CDH1, ESR1
4gastric cancer risk after h. pylori infection10.5CDH1
5syringoma10.4MUC1
6cerebral meningioma10.4PRLR
7cystadenocarcinoma10.4MUC1
8progesterone resistance10.4ESR1
9prostatic hypertrophy10.3FGFR1, ESR2
10breast disease10.3
11microinvasive gastric cancer10.3CTNNA1, CDH1
12goblet cell carcinoid10.2CTNNB1, CDH1
13mammary paget's disease10.2ESR1, MUC1
14endometrial stromal sarcoma10.2ESR1, ESR2
15inflammatory breast carcinoma10.2CDH1, ESR1
16malignant pleural mesothelioma10.2CTNNA1, MUC1
17neuroendocrine tumor10.2CDH1, MUC1
18osteoporosis10.2ESR1, ESR2
19abrikosov's tumor10.2ESR1, MUC1
20breast ductal carcinoma10.2CDH1, ESR1, ESR2
21salivary gland adenoid cystic carcinoma10.2CTNNA1, CDH1, MUC1
22mesothelioma, somatic10.1MUC1, CDH1, CTNNA1
23gynecomastia10.1
24small cell carcinoma10.1
25cholangiocarcinoma10.1CTNNA1, CDH1, MUC1
26malignant mixed mullerian tumor10.1MUC1, CTNNB1
27chondrosarcoma10.1FGFR1, CTNNA1, MUC1
28papillary carcinoma10.1CDH1, MUC1, ESR1
29li-fraumeni syndrome10.1ESR2, ESR1, PRLR
30mucoepidermoid carcinoma10.1MUC1, CTNNA1
31gallbladder cancer10.1CTNNA1, CDH1
32sarcoma, synovial10.1MUC1, CDH1, CTNNB1
33endometriosis10.1ESR2, ESR1, PRLR
34pancreatic cancer10.0ESR2, MUC1, CTNNB1
35meningioma, familial10.0PRLR, MUC1, ESR1
36bladder cancer, somatic9.9CTNNA1, CDH1, HSP90AA1
37thyroid cancer, anaplastic9.9CDH1, CTNNB1
38colon adenocarcinoma9.9CTNND1, CTNNB1, CDH1, ESR2
39adenomatous polyposis coli9.8CDH1, CTNNB1, CTNND1, CTNNA1
40thyroid carcinoma, papillary9.8ESR2, CDH1, CTNNB1, CTNNA1, FGFR1
41lymphoma, non-hodgkin9.8HSP90AA1, CTNND1, FGFR1
42lung cancer susceptibility 39.8ESR2, MUC1, CDH1, CTNNB1, CTNNA1
43infertility9.7PRLR, ESR1, ESR2, HSP90AA1
44glioblastoma9.7HSP90AA1, PRLR, CTNNA1, FGFR1
45ovarian cancer, somatic9.7CTNNB1, CDH1, MUC1, ESR1, ESR2
46colorectal cancer9.7ESR2, CDH1, CTNNB1, CTNND1, CTNNA1
47tubular adenocarcinoma9.7ESR1, MUC1, CDH1, CTNNB1, CTNNA1
48endometrial cancer9.7ESR2, ESR1, CDH1, CTNNB1, CTNND1
49burkitt lymphoma9.6HSP90AA1, MUC1, PRLR, FGFR1
50lung cancer9.6HSP90AA1, ESR2, CDH1, CTNND1, CTNNA1

Graphical network of the top 20 diseases related to Lobular Neoplasia:



Diseases related to lobular neoplasia

Symptoms for Lobular Neoplasia

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Drugs & Therapeutics for Lobular Neoplasia

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Drug clinical trials:

Search ClinicalTrials for Lobular Neoplasia

Search NIH Clinical Center for Lobular Neoplasia

Genetic Tests for Lobular Neoplasia

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Anatomical Context for Lobular Neoplasia

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MalaCards organs/tissues related to Lobular Neoplasia:

31
Breast

Animal Models for Lobular Neoplasia or affiliated genes

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Publications for Lobular Neoplasia

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Articles related to Lobular Neoplasia:

(show top 50)    (show all 76)
idTitleAuthorsYear
1
Inter-observer variability between general pathologists and a specialist in breast pathology in the diagnosis of lobular neoplasia, columnar cell lesions, atypical ductal hyperplasia and ductal carcinoma in situ of the breast. (24948027)
2014
2
Evolving concepts in breast lobular neoplasia and invasive lobular carcinoma, and their impact on imaging methods. (24633840)
2014
3
Lobular neoplasia: morphology and management. (25268198)
2014
4
Mucinous breast carcinoma with a lobular neoplasia component: a subset with aberrant expression of cell adhesion and polarity molecules and lack of neuroendocrine differentiation. (24888775)
2014
5
Lobular neoplasia. (24882347)
2014
6
Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry. (24441664)
2014
7
Classic lobular neoplasia on core biopsy: a clinical and radio-pathologic correlation study with follow-up excision biopsy. (23307062)
2013
8
Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry. (23759937)
2013
9
Long-term follow-up of lobular neoplasia (atypical lobular hyperplasia/lobular carcinoma in situ) diagnosed on core needle biopsy. (22847124)
2012
10
Cadherin-catenin complex dissociation in lobular neoplasia of the breast. (22080244)
2012
11
Hsa-miR-375 is differentially expressed during breast lobular neoplasia and promotes loss of mammary acinar polarity. (21953071)
2012
12
Lobular lesions of the breast: imaging findings of lobular neoplasia and invasive lobular carcinoma. (22324264)
2012
13
Surgical outcome of biopsy-proven lobular neoplasia: is there any difference between lobular carcinoma in situ and atypical lobular hyperplasia? (22268170)
2012
14
Is excisional biopsy required after a breast core biopsy yields lobular neoplasia? (22997389)
2012
15
Pathologic findings of follow-up surgical excision for lobular neoplasia on breast core biopsy performed for calcification. (22706860)
2012
16
Lobular neoplasia: how to manage with partial understanding. (22106558)
2011
17
In situ lobular neoplasia of the breast with marked myoepithelial proliferation. (21707709)
2011
18
Lobular neoplasia displaying central necrosis: a potential diagnostic pitfall. (20359832)
2010
19
Concurrent lobular neoplasia increases the risk of ipsilateral breast cancer recurrence in patients with ductal carcinoma in situ treated with breast-conserving therapy. (19170233)
2009
20
Epigenetic silencing in non-neoplastic epithelia identifies E-cadherin (CDH1) as a target for chemoprevention of lobular neoplasia. (19294736)
2009
21
Is excisional biopsy indicated for patients with lobular neoplasia diagnosed on percutaneous core needle biopsy of the breast? (19969131)
2009
22
Sampling lobular neoplasia of the breast: underestimation despite technical success? (19466452)
2009
23
Lobular neoplasia in vacuum-assisted breast biopsy: extended protocols and underestimation. (18356422)
2008
24
Lobular neoplasia: is surgical excision warranted? (18306873)
2008
25
Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma. (18587329)
2008
26
Lobular neoplasia: core needle breast biopsy underestimation of malignancy in relation to radiologic and pathologic features. (18619840)
2008
27
In situ and invasive lobular neoplasia of the breast. (18171417)
2008
28
Lobular neoplasia on core needle biopsy does not require excision. (18348299)
2008
29
Frequency and clinical significance of simultaneous association of lobular neoplasia and columnar cell alterations in breast tissue specimens. (18628095)
2008
30
Non-operative breast pathology: lobular neoplasia. (17182661)
2007
31
Wider excision following core biopsies of lobular neoplasia. (17983415)
2007
32
Flat epithelial atypia (DIN 1a, atypical columnar change): an underdiagnosed entity very frequently coexisting with lobular neoplasia. (17543075)
2007
33
Should the extent of lobular neoplasia on core biopsy influence the decision for excision? (17214794)
2007
34
High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. (17325484)
2007
35
Lobular neoplasia diagnosed at core biopsy does not mandate surgical excision. (17662303)
2007
36
Management of lobular neoplasia diagnosed by core needle biopsy: study of 52 biopsies with follow-up surgical excision. (17629481)
2007
37
Genomic alterations in lobular neoplasia: a microarray comparative genomic hybridization signature for early neoplastic proliferationin the breast. (16897748)
2006
38
Lobular neoplasia in breast core needle biopsy specimens is associated with a low risk of ductal carcinoma in situ or invasive carcinoma on subsequent excision. (16891208)
2006
39
Lobular neoplasia at 11-gauge vacuum-assisted stereotactic biopsy: correlation with surgical excisional biopsy and mammographic follow-up. (16985141)
2006
40
Lobular Neoplasia within a Myoid Hamartoma of the Breast. (14717763)
2004
41
Lobular neoplasia on core-needle biopsy--clinical significance. (15481097)
2004
42
In-situ lobular neoplasia: time for an awakening. (12531570)
2003
43
Atypical cystic lobules in patients with lobular neoplasia. (11584316)
2001
44
Lobular neoplasia. Long term risk of breast cancer and relation to other factors. (8780540)
1996
45
Gynecomastia with unusual intraductal "clear cell" changes mimicking pagetoid ductal spread of lobular neoplasia. (7567685)
1995
46
Coexisting lobular neoplasia and carcinoma of the breast. (6297702)
1983
47
Lobular carcinoma in situ: (lobular neoplasia) of the breast (a symposium). (7443306)
1980
48
Morphometric and cytophotometric investigations of lobular neoplasia of the breast with ductal involvement. (468888)
1979
49
The nuclear DNA content of lobular neoplasia of the mammary gland. (578099)
1977
50
Neoplastic proliferation of the epithelium of the mammary lobules: adenosis, lobular neoplasia, and small cell carcinoma. (5020552)
1972

Variations for Lobular Neoplasia

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Cosmic variations for Lobular Neoplasia:

7 (show all 53)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1776PIK3CAbreast,NS,carcinoma,lobular carcinoma3
2757PIK3CAbreast,NS,carcinoma,lobular carcinoma3
329328PIK3CAbreast,NS,carcinoma,lobular carcinoma3
4762PIK3CAbreast,NS,carcinoma,lobular carcinoma3
5760PIK3CAbreast,NS,carcinoma,lobular carcinoma3
6764PIK3CAbreast,NS,carcinoma,lobular carcinoma3
712592PIK3CAbreast,NS,carcinoma,lobular carcinoma3
8746PIK3CAbreast,NS,carcinoma,lobular carcinoma3
9775PIK3CAbreast,NS,carcinoma,lobular carcinoma3
1029325PIK3CAbreast,NS,carcinoma,lobular carcinoma3
11763PIK3CAbreast,NS,carcinoma,lobular carcinoma3
1210725TP53breast,NS,carcinoma,lobular carcinoma3
1311552TP53breast,NS,carcinoma,lobular carcinoma3
1411196TP53breast,NS,carcinoma,lobular carcinoma3
1510648TP53breast,NS,carcinoma,lobular carcinoma3
1610662TP53breast,NS,carcinoma,lobular carcinoma3
1710726TP53breast,NS,carcinoma,lobular carcinoma3
1843606TP53breast,NS,carcinoma,lobular carcinoma3
1910768TP53breast,NS,carcinoma,lobular carcinoma3
2010722TP53breast,NS,carcinoma,lobular carcinoma3
2110728TP53breast,NS,carcinoma,lobular carcinoma3
2243695TP53breast,NS,carcinoma,lobular carcinoma3
2319783CDH1breast,NS,carcinoma in situ,lobular carcinoma in situ3
2419778CDH1breast,NS,carcinoma in situ,lobular carcinoma in situ3
2519516CDH1breast,NS,carcinoma in situ,lobular carcinoma in situ3
2620783CDH1breast,NS,carcinoma,lobular carcinoma3
2719777CDH1breast,NS,carcinoma in situ,lobular carcinoma in situ3
2814060ERBB2breast,NS,carcinoma,lobular carcinoma3
2948358ERBB2breast,NS,carcinoma,lobular carcinoma3
3014065ERBB2breast,NS,carcinoma,lobular carcinoma3
3151317ERBB2breast,NS,carcinoma,lobular carcinoma3
32518KRASbreast,NS,carcinoma,lobular carcinoma3
33527KRASbreast,NS,carcinoma,lobular carcinoma3
346163FGFR4breast,NS,carcinoma,lobular carcinoma3
35131776ERBB4breast,NS,carcinoma,lobular carcinoma3
36133666BRCA1breast,NS,carcinoma,lobular carcinoma3
3733765AKT1breast,NS,carcinoma,lobular carcinoma3
38616ATMbreast,NS,carcinoma,lobular carcinoma3
39617ATRbreast,NS,carcinoma,lobular carcinoma3
40599EPHA1breast,NS,carcinoma,lobular carcinoma3
41625EPHA6breast,NS,carcinoma,lobular carcinoma3
42607MAP3K12breast,NS,carcinoma,lobular carcinoma3
43647SMG1breast,NS,carcinoma,lobular carcinoma3
4451315RASEFbreast,NS,carcinoma,lobular carcinoma3
45649SNRKbreast,NS,carcinoma,lobular carcinoma3
4617721VHLbreast,NS,carcinoma,lobular carcinoma3
47163487PIK3CBbreast,NS,carcinoma,lobular carcinoma3
48612NTRK3breast,NS,carcinoma,lobular carcinoma3
49162148LHCGRbreast,NS,carcinoma,lobular carcinoma3
50605LYNbreast,NS,carcinoma,lobular carcinoma3
51637WNK1breast,NS,carcinoma,lobular carcinoma3
52162696MXI1breast,NS,carcinoma,lobular carcinoma3
5351310LEPREL1breast,NS,carcinoma,lobular carcinoma3

Expression for genes affiliated with Lobular Neoplasia

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Search GEO for disease gene expression data for Lobular Neoplasia.

Pathways for genes affiliated with Lobular Neoplasia

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Pathways related to Lobular Neoplasia according to GeneCards Suite gene sharing:

(show all 50)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8ESR2, PRLR
29.8CTNNB1, CDH1
3
Show member pathways
9.6CTNNA1, CTNNB1
49.6ESR2, ESR1
5
Show member pathways
9.6ESR2, ESR1
69.6ESR1, ESR2
79.6ESR1, ESR2
8
Show member pathways
9.5PRLR, ESR1
99.5FGFR1, CTNND1, CDH1
109.5CDH1, CTNNB1, FGFR1
11
Show member pathways
Development ERBB family signaling58
Development GDNF family signaling58
9.4CTNNB1, CDH1, MUC1
129.4CTNNB1, CDH1, MUC1
139.4CTNNA1, CTNND1, CDH1
149.4CDH1, CTNNB1, CTNNA1
159.4CTNNA1, CTNNB1, CDH1
169.4CTNNA1, CTNNB1, CDH1
17
Show member pathways
RAC1 signaling pathway36
9.4CTNNA1, CTNNB1, CDH1
189.4CTNNA1, CTNNB1, CDH1
19
Show member pathways
Signal transduction PTEN pathway58
9.4CTNNA1, CTNNB1, CDH1
209.4CTNNA1, CTNNB1, CDH1
219.4CTNNA1, CTNNB1, CDH1
229.3HSP90AA1, ESR1
239.3ESR1, HSP90AA1
249.2CTNNB1, CTNND1, CTNNA1
259.2CTNNA1, CTNND1, CTNNB1
269.2CTNNA1, CTNND1, CTNNB1
27
Show member pathways
Prolactin Signaling Pathway36
Development Prolactin receptor signaling58
Leptin signaling pathway36
9.2ESR2, ESR1, PRLR
28
Show member pathways
9.2FGFR1, PRLR, ESR1
299.1ESR1, CDH1, CTNNB1
309.1ESR1, CTNNB1, FGFR1
31
Show member pathways
9.0CDH1, CTNNB1, CTNND1, FGFR1
329.0CDH1, CTNNB1, CTNND1, CTNNA1
339.0CDH1, CTNNB1, CTNND1, CTNNA1
349.0CDH1, CTNNB1, CTNND1, CTNNA1
35
Show member pathways
9.0CDH1, CTNNB1, CTNND1, CTNNA1
369.0CDH1, CTNNB1, CTNND1, CTNNA1
379.0CDH1, CTNNB1, CTNND1, CTNNA1
38
Show member pathways
9.0CDH1, CTNNB1, CTNND1, CTNNA1
398.9CTNNB1, CTNND1, CTNNA1, FGFR1
40
Show member pathways
Signaling Pathways in Glioblastoma36
8.9HSP90AA1, CDH1, CTNNB1, FGFR1
41
Show member pathways
8.8HSP90AA1, CTNNB1, CTNNA1, FGFR1
428.8ESR2, ESR1, CTNNB1, FGFR1
43
Show member pathways
8.7HSP90AA1, ESR2, ESR1, FGFR1
44
Show member pathways
8.7CDH1, CTNNB1, CTNND1, CTNNA1, FGFR1
458.7FGFR1, CTNNA1, CTNND1, CTNNB1, CDH1
468.6MUC1, CDH1, CTNNB1, CTNND1, CTNNA1
47
Show member pathways
Cytoskeleton remodeling FAK signaling58
Development Endothelin 1 EDNRA transactivation of EGFR58
8.6HSP90AA1, ESR2, ESR1, CTNNB1
488.6HSP90AA1, CDH1, CTNNB1, CTNNA1, FGFR1
49
Show member pathways
8.0HSP90AA1, ESR2, ESR1, CDH1, CTNNB1, FGFR1
50
Show member pathways
7.4ESR2, ESR1, MUC1, CDH1, CTNNB1, CTNND1

Compounds for genes affiliated with Lobular Neoplasia

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Compounds related to Lobular Neoplasia according to GeneCards Suite gene sharing:

(show top 50)    (show all 137)
idCompoundScoreTop Affiliating Genes
1ly 117018439.9ESR2, ESR1
217alpha estradiol439.9ESR2, ESR1
32,4,6-trichloro-4-biphenylol439.8ESR2, ESR1
4isobutylparaben439.8ESR1, ESR2
5isopropylparaben439.8ESR1, ESR2
64-octylphenol439.8ESR1, ESR2
7butylparaben439.8ESR2, ESR1
8methylparaben439.7ESR1, ESR2
9r,r-thc289.7ESR1, ESR2
10lasofoxifene439.7ESR2, ESR1
11zeranol439.6ESR1, ESR2
12crcs439.4CTNNB1, CDH1, MUC1
1312-o-tetradecanoylphorbol 13-acetate439.2CTNNA1, FGFR1, CDH1, PRLR, MUC1
14gefitinib43 49 1211.2CTNNB1, ESR2, CDH1, ESR1
15bicalutamide43 59 1211.2ESR1, ESR2, CTNNB1
16nocodazole43 1210.2HSP90AA1, CDH1, CTNNB1, CTNND1
17progestin439.1CDH1, PRLR, ESR2, ESR1, MUC1
18indole-3-carbinol439.0CTNNB1, ESR1, CDH1
194-hydroxytamoxifen439.0CTNNB1, ESR1, ESR2, HSP90AA1
20geldanamycin43 49 59 1212.0CDH1, HSP90AA1, ESR1, CTNNB1
21trastuzumab43 49 1211.0HSP90AA1, CTNNB1, MUC1, ESR1
22butyrate438.9MUC1, CDH1, PRLR, CTNNB1, HSP90AA1
23mg 13243 599.9ESR1, HSP90AA1, CDH1, CTNNB1
245-aza-2deoxycytidine438.9CTNNB1, ESR1, CDH1, ESR2, CTNNA1
25gnrh438.9ESR1, PRLR, CTNNB1, FGFR1, ESR2
26phosphotyrosine438.7FGFR1, PRLR, CDH1, CTNNA1, CTNNB1, CTNND1
275fluorouracil438.7CTNNB1, MUC1, HSP90AA1, ESR1, CDH1
28vitamin d438.7CDH1, CTNNB1, HSP90AA1, ESR2, ESR1
29mifepristone43 28 59 1211.7MUC1, ESR1, ESR2, HSP90AA1, CTNNB1
30doxorubicin43 49 1210.7HSP90AA1, ESR2, ESR1, CDH1, CTNNB1
31ly294002438.7FGFR1, CDH1, CTNNB1, ESR1, HSP90AA1
32dexamethasone43 49 28 1211.6CDH1, CTNNB1, HSP90AA1, MUC1, ESR2, PRLR
33glutamate438.6HSP90AA1, FGFR1, CTNNB1, CDH1, PRLR, ESR2
34cisplatin43 49 59 1211.6MUC1, CTNNB1, CDH1, ESR1, HSP90AA1
35threonine438.5FGFR1, HSP90AA1, MUC1, PRLR, CTNNB1, CTNND1
36dihydrotestosterone43 28 24 1211.4MUC1, ESR1, HSP90AA1, CTNNB1, ESR2, CDH1
37cysteine438.4FGFR1, CTNNB1, CDH1, PRLR, HSP90AA1, ESR2
38steroid438.3ESR1, ESR2, HSP90AA1, FGFR1, CTNNB1, PRLR
39paraffin438.2ESR2, ESR1, PRLR, CDH1, CTNNB1, CTNNA1
40genistein43 28 59 2 24 1213.1FGFR1, CDH1, PRLR, ESR1, ESR2, HSP90AA1
41retinoic acid43 249.1HSP90AA1, ESR1, MUC1, CDH1, CTNNB1, FGFR1
42tamoxifen43 49 28 1211.1CTNNB1, ESR2, CDH1, PRLR, MUC1, ESR1
43serine438.0FGFR1, HSP90AA1, ESR2, PRLR, CDH1, CTNNB1
44paclitaxel43 49 1210.0FGFR1, HSP90AA1, ESR1, CDH1, CTNNB1, CTNND1
45cycloheximide437.9CTNNB1, PRLR, ESR1, ESR2, HSP90AA1
46tyrosine437.9CTNNA1, MUC1, FGFR1, CTNND1, CTNNB1, CDH1
47progesterone43 28 59 24 1211.8ESR2, FGFR1, CTNNB1, CDH1, MUC1, HSP90AA1
48testosterone43 59 24 1210.8FGFR1, CDH1, CTNNB1, PRLR, ESR1, MUC1
49estrogen437.4HSP90AA1, ESR2, ESR1, MUC1, PRLR, CDH1
50vegf437.4FGFR1, HSP90AA1, ESR2, ESR1, MUC1, CDH1

GO Terms for genes affiliated with Lobular Neoplasia

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Cellular components related to Lobular Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmic side of plasma membraneGO:00098989.8CTNNB1, CDH1
2cell-cell adherens junctionGO:00059139.7CTNNB1, CDH1
3catenin complexGO:00163429.6CTNNA1, CTNNB1, CDH1
4zonula adherensGO:00059159.4CTNNB1, CTNND1, CTNNA1
5cell-cell junctionGO:00059119.3CTNNB1, CTNND1, CTNNA1
6lamellipodiumGO:00300279.2CTNNA1, CTNND1, CTNNB1
7extracellular regionGO:00055768.5HSP90AA1, ESR2, PRLR, CDH1, FGFR1
8plasma membraneGO:00058867.3HSP90AA1, ESR1, PRLR, CDH1, CTNNB1, CTNND1

Biological processes related to Lobular Neoplasia according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1regulation of protein localization to cell surfaceGO:0200000810.0CTNNB1, CDH1
2lung-associated mesenchyme developmentGO:00604849.9FGFR1, CTNNB1
3positive regulation of phospholipase C activityGO:00108639.8FGFR1, ESR1
4ovarian follicle developmentGO:00015419.8CTNNA1, ESR2
5uterus developmentGO:00600659.8ESR1, ESR2
6positive regulation of muscle cell differentiationGO:00511499.8CTNNA1, CTNNB1
7vagina developmentGO:00600689.7ESR1, ESR2
8adherens junction organizationGO:00343329.7CTNNA1, CTNND1, CDH1
9cell-cell junction organizationGO:00452169.7CDH1, CTNND1, CTNNA1
10positive regulation of mesenchymal cell proliferationGO:00020539.7FGFR1, CTNNB1
11intracellular estrogen receptor signaling pathwayGO:00305209.7ESR2, ESR1
12cell junction assemblyGO:00343299.7CDH1, CTNND1, CTNNA1
13cellular response to indole-3-methanolGO:00716819.7CTNNA1, CTNNB1, CDH1
14neuron migrationGO:00017649.7ESR2, CTNNB1, FGFR1
15cell-cell adhesionGO:00163379.6CTNND1, CTNNB1, CDH1
16muscle cell differentiationGO:00426929.5CTNNA1, CTNNB1
17cell maturationGO:00484699.4FGFR1, CTNNB1
18positive regulation of nitric oxide biosynthetic processGO:00454299.4HSP90AA1, ESR1

Molecular functions related to Lobular Neoplasia according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1gamma-catenin bindingGO:00452959.8CDH1, CTNNA1
2estrogen response element bindingGO:00340569.8ESR1, ESR2
3estrogen receptor activityGO:00302849.7ESR1, ESR2
4protein phosphatase bindingGO:00199039.5CTNND1, CTNNB1, CDH1
5core promoter sequence-specific DNA bindingGO:00010469.5ESR1, ESR2
6cadherin bindingGO:00452969.5CTNNB1, CTNND1, CTNNA1
7nitric-oxide synthase regulator activityGO:00302359.4ESR1, HSP90AA1
8beta-catenin bindingGO:00080139.4ESR1, CDH1, CTNNA1
9steroid bindingGO:00054969.3ESR1, ESR2
10enzyme bindingGO:00198999.1CTNNB1, ESR1, ESR2
11protein bindingGO:00055156.3FGFR1, HSP90AA1, ESR2, ESR1, MUC1, PRLR

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet