MCID: LCL009
MIFTS: 19

Localized Ewing's Sarcoma malady

Cancer diseases category

Summaries for Localized Ewing's Sarcoma

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32MalaCards
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MalaCards: Localized Ewing's Sarcoma, is also known as localized ewing's tumor An important gene associated with Localized Ewing's Sarcoma is EWSR1 (EWS RNA-binding protein 1). The compounds cyclic amp and retinoic acid have been mentioned in the context of this disorder. Affiliated tissues include bone and monocytes, and related mouse phenotype adipose tissue.

Aliases & Classifications for Localized Ewing's Sarcoma

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8Disease Ontology, 39NCIt, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

localized ewing's sarcoma 8
localized ewing's tumor 8


External Ids:

Disease Ontology8 DOID:4980
NCIt39 C7806

Related Diseases for Localized Ewing's Sarcoma

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Clinical Features for Localized Ewing's Sarcoma

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Drugs & Therapeutics for Localized Ewing's Sarcoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Localized Ewing's Sarcoma

Drug clinical trials:

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Search NIH Clinical Center for Localized Ewing's Sarcoma

Search CenterWatch for Localized Ewing's Sarcoma

Genetic Tests for Localized Ewing's Sarcoma

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Anatomical Context for Localized Ewing's Sarcoma

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32MalaCards
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MalaCards organs/tissues related to Localized Ewing's Sarcoma:

32
Bone, Monocytes

Animal Models for Localized Ewing's Sarcoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Localized Ewing's Sarcoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.1LBR, EWSR1

Publications for Localized Ewing's Sarcoma

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50PubMed
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Articles related to Localized Ewing's Sarcoma:

(show all 26)
idTitleAuthorsYear
1
Localized extraosseous Ewing's sarcoma of the chest wall resected by video-assisted thoracoscopic surgery. (21170637)
2010
2
Chemotherapy-induced tumor necrosis as a prognostic factor in localized Ewing's sarcoma of the extremities. (9193352)
1997
3
Prognostic factors in patients with localized Ewing's sarcoma: the effect on survival of actual received drug dose intensity and of histologic response to induction therapy. (9373791)
1997
4
Localization of the human oncostatin M gene (OSM) to chromosome 22q12, distal to the Ewing's sarcoma breakpoint. (8422753)
1993
5
Multimodal therapy for the management of localized Ewing's sarcoma of pelvic and sacral bones: a report from the second intergroup study. (2045857)
1991
6
Ewing's sarcoma and peripheral neuroectodermal tumors. Report of a case with laterothoracic localization]. (2173115)
1990
7
The role of surgery in the treatment of localized Ewing's sarcoma. (2095327)
1990
8
Multimodal therapy for the management of nonpelvic, localized Ewing's sarcoma of bone: intergroup study IESS-II. (2099751)
1990
9
Combined therapy of localized Ewing's sarcoma of bone: analysis of results in 100 patients. (2254107)
1990
10
Therapy for localized Ewing's sarcoma of bone. (2915236)
1989
11
Long-term results in 144 localized Ewing's sarcoma patients treated with combined therapy. (2924256)
1989
12
Neoadjuvant chemotherapy for localized Ewing's sarcoma of the extremities: preliminary results of a protocol which uses surgery (alone or followed by radiotherapy) for local control. (2603221)
1989
13
Neoadjuvant chemotherapy for localized Ewing's sarcoma. Preliminary results of a new protocol which uses surgery alone or followed by radiotherapy for local control. (16312852)
1989
14
Monoarthritis as the presenting manifestation of localized Ewing's sarcoma in an older patient. (3625649)
1987
15
Prognostic significance of tumor volume in localized Ewing's sarcoma of bone in children and adolescents. (3558454)
1987
16
Localized Ewing's sarcoma of bone: ten years' experience at the Istituto Ortopedico Rizzoli in 124 cases treated with multimodal therapy. (3987754)
1985
17
Staging, therapy and prognosis of primary non-Hodgkin's lymphoma of bone and a comparison of results with localized Ewing's sarcoma: ten years experience at the Istituto Ortopedico Rizzoli. (4049536)
1985
18
The response to initial chemotherapy as a prognostic factor in localized Ewing's sarcoma. (3839188)
1985
19
Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial. (6344980)
1983
20
The treatment of localized Ewing's sarcoma: the experience at the Istituto Ortopedico Rizzoli in 163 cases treated with and without adjuvant chemotherapy. (7066862)
1982
21
Acute monocytic leukemia complicating combined-modality therapy for localized childhood Ewing's sarcoma. (6949907)
1981
22
Indications for surgical treatment of localized Ewing's sarcoma of bone. (7449230)
1980
23
Management and results of localized Ewing's sarcoma. (106949)
1979
24
Current results with a combined treatment approach to localized Ewing's sarcoma. (752881)
1978
25
Localized Ewing's sarcoma--treatment and results. (4834171)
1974
26
Treatment of clinically localized Ewing's sarcoma with radiotherapy and combination chemotherapy. (4641761)
1972

Genetic Variations for Localized Ewing's Sarcoma

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Expression for genes affiliated with Localized Ewing's Sarcoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Localized Ewing's Sarcoma

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Pathways for genes affiliated with Localized Ewing's Sarcoma

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Compounds for genes affiliated with Localized Ewing's Sarcoma

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44Novoseek, 24HMDB
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Compounds related to Localized Ewing's Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cyclic amp44 2410.1LBR, EWSR1
2retinoic acid44 2410.1LBR, EWSR1
3arginine449.0LBR, EWSR1
4zinc44 249.8LBR, EWSR1

GO Terms for genes affiliated with Localized Ewing's Sarcoma

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Products for genes affiliated with Localized Ewing's Sarcoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Localized Ewing's Sarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet