MCID: LCL009
MIFTS: 16

Localized Ewing's Sarcoma malady

Summaries for Localized Ewing's Sarcoma

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33MalaCards
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MalaCards: Localized Ewing's Sarcoma, is also known as localized ewing's tumor An important gene associated with Localized Ewing's Sarcoma is EWSR1 (EWS RNA-binding protein 1). The compounds cyclic amp and retinoic acid have been mentioned in the context of this disorder. Related mouse phenotype adipose tissue.

Aliases & Classifications for Localized Ewing's Sarcoma

Sources:
8Disease Ontology, 40NCIt, 61UMLS
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Aliases & Descriptions:

localized ewing's sarcoma 8
localized ewing's tumor 8


External Ids:

Disease Ontology8 DOID:4980
NCIt40 C7806

Related Diseases for Localized Ewing's Sarcoma

Clinical Features for Localized Ewing's Sarcoma

Drugs & Therapeutics for Localized Ewing's Sarcoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Localized Ewing's Sarcoma

Anatomical Context for Localized Ewing's Sarcoma

Animal Models for Localized Ewing's Sarcoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Localized Ewing's Sarcoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.1LBR, EWSR1

Publications for Localized Ewing's Sarcoma

Sources:
51PubMed
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Articles related to Localized Ewing's Sarcoma:

(show all 24)
idTitleAuthorsYear
1
Localized extraosseous Ewing's sarcoma of the chest wall resected by video-assisted thoracoscopic surgery. (21170637)
2010
2
Chemotherapy-induced tumor necrosis as a prognostic factor in localized Ewing's sarcoma of the extremities. (9193352)
1997
3
Prognostic factors in patients with localized Ewing's sarcoma: the effect on survival of actual received drug dose intensity and of histologic response to induction therapy. (9373791)
1997
4
Multimodal therapy for the management of localized Ewing's sarcoma of pelvic and sacral bones: a report from the second intergroup study. (2045857)
1991
5
The role of surgery in the treatment of localized Ewing's sarcoma. (2095327)
1990
6
Multimodal therapy for the management of nonpelvic, localized Ewing's sarcoma of bone: intergroup study IESS-II. (2099751)
1990
7
Combined therapy of localized Ewing's sarcoma of bone: analysis of results in 100 patients. (2254107)
1990
8
Therapy for localized Ewing's sarcoma of bone. (2915236)
1989
9
Long-term results in 144 localized Ewing's sarcoma patients treated with combined therapy. (2924256)
1989
10
Neoadjuvant chemotherapy for localized Ewing's sarcoma of the extremities: preliminary results of a protocol which uses surgery (alone or followed by radiotherapy) for local control. (2603221)
1989
11
Neoadjuvant chemotherapy for localized Ewing's sarcoma. Preliminary results of a new protocol which uses surgery alone or followed by radiotherapy for local control. (16312852)
1989
12
Monoarthritis as the presenting manifestation of localized Ewing's sarcoma in an older patient. (3625649)
1987
13
Prognostic significance of tumor volume in localized Ewing's sarcoma of bone in children and adolescents. (3558454)
1987
14
Localized Ewing's sarcoma of bone: ten years' experience at the Istituto Ortopedico Rizzoli in 124 cases treated with multimodal therapy. (3987754)
1985
15
Staging, therapy and prognosis of primary non-Hodgkin's lymphoma of bone and a comparison of results with localized Ewing's sarcoma: ten years experience at the Istituto Ortopedico Rizzoli. (4049536)
1985
16
The response to initial chemotherapy as a prognostic factor in localized Ewing's sarcoma. (3839188)
1985
17
Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial. (6344980)
1983
18
The treatment of localized Ewing's sarcoma: the experience at the Istituto Ortopedico Rizzoli in 163 cases treated with and without adjuvant chemotherapy. (7066862)
1982
19
Acute monocytic leukemia complicating combined-modality therapy for localized childhood Ewing's sarcoma. (6949907)
1981
20
Indications for surgical treatment of localized Ewing's sarcoma of bone. (7449230)
1980
21
Management and results of localized Ewing's sarcoma. (106949)
1979
22
Current results with a combined treatment approach to localized Ewing's sarcoma. (752881)
1978
23
Localized Ewing's sarcoma--treatment and results. (4834171)
1974
24
Treatment of clinically localized Ewing's sarcoma with radiotherapy and combination chemotherapy. (4641761)
1972

Genetic Variations for Localized Ewing's Sarcoma

Expression for genes affiliated with Localized Ewing's Sarcoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Localized Ewing's Sarcoma

Search GEO for disease gene expression data for Localized Ewing's Sarcoma.

Pathways for genes affiliated with Localized Ewing's Sarcoma

Compounds for genes affiliated with Localized Ewing's Sarcoma

Sources:
45Novoseek, 24HMDB
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Compounds related to Localized Ewing's Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cyclic amp45 2410.1LBR, EWSR1
2retinoic acid45 2410.1LBR, EWSR1
3arginine459.0LBR, EWSR1
4zinc45 249.8LBR, EWSR1

GO Terms for genes affiliated with Localized Ewing's Sarcoma

Products for genes affiliated with Localized Ewing's Sarcoma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Localized Ewing's Sarcoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet