Loeys-dietz Syndrome Type 1a malady

MalaCards: Loeys-dietz Syndrome Type 1a, also known as loeys-dietz syndrome, type 1a, is related to loeys-dietz syndrome and loeys-dietz syndrome type 1b. An important gene associated with Loeys-dietz Syndrome Type 1a is TGFBR1 (transforming growth factor, beta receptor 1).

OMIM: 609192

loeys-dietz syndrome type 1a 30 loeys-dietz syndrome, type 1a 33

loeys-dietz syndrome 43 lds1a 30

Disease types for loeys-dietz syndrome family:

loeys-dietz syndrome type 1a	loeys-dietz syndrome type 1b
loeys-dietz syndrome type 2a	loeys-dietz syndrome type 2b

Diseases related to loeys-dietz syndrome type 1a by text searches and GeneDecks gene sharing:

(show all 11)

id	Related Disease	Score	Top Affiliating Genes
1	loeys-dietz syndrome	12.0
2	loeys-dietz syndrome type 1b	9.7
3	loeys-dietz syndrome type 2a	9.6
4	loeys-dietz syndrome type 2b	9.4
5	marfan syndrome/ loeys-dietz syndrome/ familial thoracic aortic aneurysms and dissections multi-gene panels	9.4
6	smad3-related loeys-dietz syndrome	9.4
7	tgfb2-related loeys-dietz syndrome	9.0
8	marfan syndrome	9.0
9	tgfbr1-related loeys-dietz syndrome	9.0
10	tgfbr2-related loeys-dietz syndrome	9.0
11	lymphoblastic lymphoma	5.7

Clinical features from OMIM: 609192

Approved drugs:

Drug clinical trials:

Genes related to loeys-dietz syndrome type 1a according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	TGFBR1	transforming growth factor, beta receptor 1	11.1	Disorders