LQT
MCID: LNG028
MIFTS: 61

Long Qt Syndrome (LQT) malady

Summaries for Long Qt Syndrome

About this section
Sources:
8Disease Ontology, 42NIH Rare Diseases, 63Wikipedia, 46OMIM, 19GeneReviews, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
NIH Rare Diseases:42 Long qt syndrome is a disorder of the heart’s electrical activity that can cause sudden, uncontrollable, and irregular heartbeats (arrhythmia), which may lead to sudden death. long qt syndrome can be detected by electrocardiogram (ekg). it can be caused by a variety of different gene mutations (changes). it can also be acquired (noninherited) and may be brought on by certain medicines and other medical conditions. last updated: 10/4/2013

MalaCards: Long Qt Syndrome, also known as romano-ward syndrome, is related to brugada syndrome and long qt syndrome 1. An important gene associated with Long Qt Syndrome is SCN5A (sodium channel, voltage-gated, type V, alpha subunit), and among its related pathways are Gastric acid secretion and Potassium transporters: inward current. The compounds chromanol and clofilium have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and brain, and related mouse phenotypes are homeostasis/metabolism and cardiovascular system.

Disease Ontology:8 An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (tdp, a form of irregular heartbeat that originates from the ventricles).

Wikipedia:63 Long QT syndrome (LQTS) is a rare inherited heart condition in which delayed repolarization of the heart... more...

Description from OMIM:46 611818, 603830, 613688, 613485, 612955 611819, 613695, 192500, 601005, 613693, 170390, 611820 more

GeneReviews summary for rws

Aliases & Classifications for Long Qt Syndrome

About this section
Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 20GeneTests, 22GTR, 19GeneReviews, 46OMIM, 56SNOMED-CT, 27ICD9CM, 39NCIt, 34MeSH
See all sources

Aliases & Descriptions:

long qt syndrome 8 42 10 44 60
romano-ward syndrome 8 19 60
long q-t syndrome 8 20 22
long qt syndrome, autosomal dominant 19
romano-ward long qt syndrome 19
lqt 8


External Ids:

Disease Ontology8 DOID:2843
ICD9CM27 426.82
NCIt39 C34786
MeSH34 D008133

Related Diseases for Long Qt Syndrome

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Long Qt Syndrome 1 family:

long qt syndrome Long Qt Syndrome 10
Long Qt Syndrome 11 Long Qt Syndrome 2
Long Qt Syndrome 3 Long Qt Syndrome 4
Long Qt Syndrome 5 Long Qt Syndrome 6
Long Qt Syndrome 8 Long Qt Syndrome 9
Long Qt Syndrome 12 Long Qt Syndrome 13
Long Qt Syndrome-2, Acquired Long Qt Syndrome 1, Acquired

Diseases related to Long Qt Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 85)
idRelated DiseaseScoreTop Affiliating Genes
1brugada syndrome31.0KCNH2, KCNE2, KCNE1L, SCN5A, SCN4B, ANK2
2long qt syndrome 130.9KCNE1, KCNQ1, KCNH2, KCNE2, SCN5A
3atrioventricular block30.9KCNH2, SCN5A
4sudden infant death syndrome30.9CAV3, SCN5A
5jervell-lange nielsen syndrome30.8KCNE1, KCNQ1
6epilepsy syndrome30.7KCNH2, KCNQ1, ZACN, KCNJ5
7catecholaminergic polymorphic ventricular tachycardia30.7RYR2
8timothy syndrome30.7KCNE1, SCN4B
9sudden cardiac death multi-gene panels30.4RYR2, MYH7, ANK2, SCN5A, KCNJ2, KCNH2
10familial atrial fibrillation30.3SCN5A, KCNQ1, KCNE2
11congenital heart defect30.1KCNQ1, RYR2, KCNJ2
12andersen-tawil syndrome10.5
13long qt syndrome 310.5
14hypertrophic cardiomyopathy10.5
15short qt syndrome10.5
16long qt syndrome 1110.5
17long qt syndrome 210.5
18long qt syndrome 510.5
19long qt syndrome 610.5
20long qt syndrome 910.5
21long qt syndrome 1210.5
22long qt syndrome 1310.5
23syndactyly10.5
24n syndrome10.5
25long qt syndrome 1010.5
26long qt syndrome 410.5
27long qt syndrome 810.5
28scn5a-related romano ward syndrome10.4
29hypokalemia10.3
30dilated cardiomyopathy10.3
31epiphyseal dysplasia multiple with early-onset diabetes mellitus10.3
32kearns-sayre syndrome10.2
33beckwith-wiedemann syndrome10.2
34tetralogy of fallot10.2
35familial hypertrophic cardiomyopathy10.2
36adult syndrome10.2
37williams syndrome10.2
38long qt syndrome 1, acquired10.2
39acquired long qt syndrome, reduced10.2
40right bundle branch block10.1
41marfan syndrome10.1
42supravalvular aortic stenosis10.1
43primary hyperparathyroidism10.1
44hypoparathyroidism10.1
45arrhythmogenic right ventricular dysplasia10.1
46congenital generalized lipodystrophy10.1
47panhypopituitarism10.1
48hemochromatosis10.1
49pain disorder10.1
50conduct disorder10.1

Graphical network of the top 20 diseases related to Long Qt Syndrome:



Diseases related to long qt syndrome

Clinical Features for Long Qt Syndrome

About this section
Sources:
46OMIM
See all sources

Clinical features from OMIM:

611818, 603830, 613688, 613485, 612955, 611819, 613695, 192500, 601005, 613693 170390, 611820 more

Drugs & Therapeutics for Long Qt Syndrome

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Long Qt Syndrome

Drug clinical trials:

Search ClinicalTrials for Long Qt Syndrome

Search NIH Clinical Center for Long Qt Syndrome

Search CenterWatch for Long Qt Syndrome

Genetic Tests for Long Qt Syndrome

About this section
Sources:
20GeneTests, 22GTR
See all sources

Genetic tests related to Long Qt Syndrome:

id Genetic test Affiliating Genes
1 Long Qt Syndrome Multi-Gene Panels20
2 Long Qt Syndrome22

Anatomical Context for Long Qt Syndrome

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Long Qt Syndrome:

32
Heart, Testes, Brain, Eye

Animal Models for Long Qt Syndrome or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Long Qt Syndrome:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053769.9KCNE1, KCNH2, KCNE2, KCNJ2, CAV3, SNTA1
2MP:00053859.8RYR2, KCND3, KCNJ5, KCNQ1, KCNE1, KCNH2
3MP:00053699.8KCNQ1, KCNH2, KCNJ2, CAV3, SCN5A, SNTA1

Publications for Long Qt Syndrome

About this section
Sources:
50PubMed
See all sources

Articles related to Long Qt Syndrome:

(show top 50)    (show all 843)
idTitleAuthorsYear
1
A novel mutation in the transmembrane nonpore region of the KCNH2 gene causes severe clinical manifestations of long QT syndrome. (23010577)
2013
2
A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome. (22977222)
2013
3
Long QT syndrome in South Africa: the results of comprehensive genetic screening. (24217263)
2013
4
Safe drug use in long QT syndrome and Brugada syndrome: comparison of website statistics. (23533266)
2013
5
An NMR investigation of the structure, function and role of the hERG channel selectivity filter in the long QT syndrome. (23473737)
2013
6
Mechanistic basis for type 2 long QT syndrome caused by KCNH2 mutations that disrupt conserved arginine residues in the voltage sensor. (23546015)
2013
7
A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward). (21907427)
2012
8
Competitive sports participation in athletes with congenital long QT syndrome. (22820673)
2012
9
Arrhythmogenic mechano-electric heterogeneity in the long-QT syndrome. (22841828)
2012
10
Long QT syndrome with nocturnal cardiac events caused by a KCNH2 missense mutation (G604S). (22821100)
2012
11
Exercise and vagal reflex in long QT syndrome type 1. (23158535)
2012
12
Isoform-specific dominant-negative effects associated with hERG1 G628S mutation in long QT syndrome. (22876326)
2012
13
Genesis of phase 3 early afterdepolarizations and triggered activity in acquired long-QT syndrome. (21078812)
2011
14
Left ventricular noncompaction syndrome masquerading or misdiagnosed as congenital long QT syndrome: remember QT prolongation does not equal long QT syndrome. (21696549)
2011
15
Prevalence of long QT syndrome and other cardiac defects in deaf-mute children. (22830134)
2011
16
Drug-induced long QT syndrome. (21079043)
2010
17
Is long QT syndrome a disease of abnormal mechanical contraction? (20855657)
2010
18
Assessment of microvolt T-wave alternans in high-risk patients with the congenital long-QT syndrome. (19804510)
2009
19
Depressive symptoms in the congenital long QT syndrome. (19551538)
2009
20
Channelopathies: Brugada syndrome, long QT syndrome, short QT syndrome, and CPVT. (19575158)
2009
21
Misdiagnosis of long QT syndrome as epilepsy at first presentation. (19282063)
2009
22
Giant T-U waves precede torsades de pointes in long QT syndrome: a systematic electrocardiographic analysis in patients with acquired and congenital QT prolongation. (19573731)
2009
23
NOS1AP is a genetic modifier of the long-QT syndrome. (19822806)
2009
24
Identification of a novel KCNQ1 mutation associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long QT syndrome in a Chinese family. (18400097)
2008
25
Mutation of an A-kinase-anchoring protein causes long-QT syndrome. (18093912)
2007
26
Preparation, functional characterization, and NMR studies of human KCNE1, a voltage-gated potassium channel accessory subunit associated with deafness and long QT syndrome. (17892302)
2007
27
Mutation screening in KCNQ1, HERG, KCNE1, KCNE2 and SCN5A genes in a long QT syndrome family. (17597962)
2007
28
A single hERG mutation underlying a spectrum of acquired and congenital long QT syndrome phenotypes. (17531263)
2007
29
Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene. (17470695)
2007
30
Compound heterozygosity for mutations Asp611-->Tyr in KCNQ1 and Asp609-->Gly in KCNH2 associated with severe long QT syndrome. (15500450)
2005
31
Mutations in the HERG K+-ion channel: a novel link between long QT syndrome and sudden infant death syndrome. (15670565)
2005
32
Does KCNE5 play a role in long QT syndrome? (15193977)
2004
33
Mutation site-specific differences in arrhythmic risk and sensitivity to sympathetic stimulation in the LQT1 form of congenital long QT syndrome: multicenter study in Japan. (15234419)
2004
34
Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome. (15572053)
2004
35
Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG. (15043509)
2004
36
Risk stratification in the long-QT syndrome. (12736279)
2003
37
The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations. (11741928)
2002
38
Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-A -go-go-Related Gene. (12270925)
2002
39
DHPLC analysis of potassium ion channel genes in congenital long QT syndrome. (12402336)
2002
40
Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death. (11334834)
2001
41
Long QT syndrome in children: the value of the rate corrected QT interval in children who present with fainting. (11743033)
2001
42
Long QT syndrome in children: the value of rate corrected QT interval and DNA analysis as screening tests in the general population. (11743032)
2001
43
Cardiac K+ channels and drug-acquired long QT syndrome. (10860023)
2000
44
Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome. (10400998)
1999
45
A single Na(+) channel mutation causing both long-QT and Brugada syndromes. (10590249)
1999
46
Novel missense mutation (G601S) of HERG in a Japanese long QT syndrome family. (9452080)
1998
47
New mutations in the KVLQT1 potassium channel that cause long-QT syndrome. (9570196)
1998
48
A molecular basis for the therapy of the long QT syndrome. (8952843)
1996
49
Recent advances in understanding the molecular mechanisms of the long QT syndrome. (8589871)
1995
50
Scintigraphic pattern of regional cardiac sympathetic innervation in patients with familial long QT syndrome using positron emission tomography. (8491017)
1993

Genetic Variations for Long Qt Syndrome

About this section

Expression for genes affiliated with Long Qt Syndrome

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Long Qt Syndrome

Search GEO for disease gene expression data for Long Qt Syndrome.

Pathways for genes affiliated with Long Qt Syndrome

About this section
Sources:
29KEGG, 12EMD Millipore, 37NCBI BioSystems Database, 53Reactome, 51QIAGEN, 49PharmGKB
See all sources

Compounds for genes affiliated with Long Qt Syndrome

About this section
Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 49PharmGKB, 24HMDB
See all sources

Compounds related to Long Qt Syndrome according to GeneCards/GeneDecks:

(show all 41)
idCompoundScoreTop Affiliating Genes
1chromanol4410.8KCNE1, KCNQ1
2clofilium44 2811.7KCNQ1, KCNH2
3indapamide44 1111.7KCNE1, KCNQ1
4chromanol 293b44 59 2812.7KCNE1, KCNQ1
5Dalfampridine 1110.7KCND2, KCND3
6mexiletine44 1111.7KCNH2, SCN5A
7flecainide44 49 28 1113.7SCN5A, KCNH2, KCND2
8propafenone44 49 28 1113.7KCNH2, SCN5A
9katp4410.7KCNH2, KCNQ1, KCNJ5
10isoleucine4410.7KCNQ1, KCNH2, SCN5A
11pip22810.7KCNQ1, KCNJ5
12qx 314 chloride5910.7SCN5A, SCN4B
13glibenclamide44 28 49 5913.7KCNJ5, KCNQ1, KCNJ2
14cromakalim44 2811.6KCNQ1, KCNJ5
15tetrodotoxin citrate5910.6SCN5A, SCN4B
16tetraethylammonium44 28 1112.6KCNJ5, KCNQ1, KCNH2, KCNJ2
17phrixotoxin 35910.6SCN5A, SCN4B
18disopyramide44 1111.6KCND2, KCND3, KCNJ5, SCN5A
19ryanodine44 28 5912.6ANK2, MYH7, RYR2
20p10755910.6KCNJ5, KCNJ2
21levcromakalim5910.5KCNJ5, KCNJ2
22e-4031 dihydrochloride5910.5KCNQ1, KCNE1, KCNH2, KCNE2, KCND3, KCND2
23xe 991 dihydrochloride5910.5KCND2, KCND3, KCNQ1, KCNE1, KCNE2, KCNH2
24jnj 3035910.5KCNE2, KCNH2, KCNE1, KCNQ1, KCND3, KCND2
25shk-dap225910.5KCNE2, KCNH2, KCNE1, KCNQ1, KCND3, KCND2
26ica 1103815910.5KCNE2, KCNH2, KCNE1, KCNQ1, KCND3, KCND2
27tertiapin-q5910.5KCNJ5, KCNJ2
28veratridine44 59 2812.5SCN5A, SCN4B
29arginine4410.5KCNQ1, KCNE1, KCNH2, KCNJ2, SCN5A, MYH7
30isoproterenol44 1111.5KCNQ1, KCNH2, KCNJ2, CAV3, MYH7, RYR2
31bepridil44 28 1112.5KCNQ1, KCNH2
32phospholipid4410.5KCNJ5, KCNE1, KCNH2, RYR2
33charybdotoxin44 2811.4KCNJ5, KCNQ1
34lipid4410.4KCND3, KCNJ5, KCNE1, KCNH2, CAV3, MYH7
35mg2+2810.3RYR2, KCNJ2
36verapamil44 49 28 11 2414.2KCNH2, SCN5A, RYR2
37sodium44 2411.2RYR2, KCNJ5, MYH7, ZACN, SNTA1, SCN4B
38nitric oxide44 11 2412.2RYR2, SNTA1, CAV3, KCNE1, KCNJ5
39potassium44 11 2412.1AKAP9, SCN5A, KCNJ2, KCNE2, KCNH2, KCNE1
40calcium44 49 11 2413.1KCND3, KCNJ5, KCNQ1, KCNH2, KCNJ2, CAV3
41cisapride44 28 1112.1SCN5A, KCNH2

GO Terms for genes affiliated with Long Qt Syndrome

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Long Qt Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel complexGO:00151810.4SCN4B, SCN5A
2sarcolemmaGO:04238310.3KCND3, KCNQ1, CAV3, SCN5A, SNTA1, ANK2
3Z discGO:03001810.2KCNE1, CAV3, ANK2, MYH7, RYR2
4T-tubuleGO:03031510.2CAV3, SCN5A, ANK2
5cell surfaceGO:00998610.1KCND2, KCNE1, KCNH2, KCNE2, CAV3, SCN5A
6intercalated discGO:01470410.0ANK2, SCN4B, SCN5A
7voltage-gated potassium channel complexGO:00807610.0AKAP9, KCND2, KCND3, KCNJ5, KCNQ1, KCNE1
8plasma membraneGO:0058869.7KCNH2, KCNE1, KCNQ1, KCNJ5, KCND3, KCND2

Biological processes related to Long Qt Syndrome according to GeneCards/GeneDecks:

(show all 40)
idNameGO IDScoreTop Affiliating Genes
1regulation of delayed rectifier potassium channel activityGO:190225910.7KCNE1, KCNE2
2membrane depolarization involved in regulation of SA node cell action potentialGO:08604610.7SCN5A, ANK2
3regulation of calcium ion transmembrane transporter activityGO:190101910.7CAV3, ANK2
4T-tubule organizationGO:03329210.7CAV3, ANK2
5SA node cell to atrial cardiac muscle cell communicationGO:08607010.7ANK2, SCN5A
6membrane depolarization involved in regulation of cardiac muscle cell action potentialGO:08601210.7SCN4B, SCN5A, KCNJ2
7membrane repolarizationGO:08600910.7KCND3, KCNE1, KCNE2
8negative regulation of potassium ion transmembrane transportGO:190138010.7KCNH2, KCNE1L, CAV3
9regulation of atrial cardiac muscle cell membrane repolarizationGO:06037210.7KCNQ1, KCNE1L, SCN5A
10membrane repolarization involved in regulation of cardiac muscle cell action potentialGO:08601310.7KCNQ1, KCNE1, KCNH2, KCNJ2
11membrane depolarization involved in regulation of action potentialGO:08601010.6SCN5A, KCNH2
12regulation of atrial cardiac muscle cell action potentialGO:08601410.6KCNQ1, KCNE1L, ANK2
13positive regulation of potassium ion transmembrane transportGO:190138110.6KCNQ1, KCNE1, KCNH2, KCNE1L
14AV node cell to bundle of His cell communicationGO:08606710.6SCN4B, SCN5A
15regulation of cardiac muscle contractionGO:05511710.6RYR2, ANK2, CAV3
16regulation of potassium ion transmembrane transportGO:190137910.6KCNE1, KCNH2, KCNE2, KCNE1L
17membrane repolarization involved in regulation of action potentialGO:08601110.6KCNQ1, KCNE1, KCNH2, KCNE2, KCNJ2
18regulation of cardiac muscle cell action potential involved in contractionGO:08600210.6KCNE1, KCNE2, KCNJ2, SCN5A, SCN4B
19cellular response to drugGO:03569010.6KCNQ1, KCNH2, KCNE2
20regulation of sodium ion transmembrane transportGO:190230510.6SCN5A, SNTA1
21sarcoplasmic reticulum calcium ion transportGO:07029610.6RYR2, ANK2
22regulation of heart contractionGO:00801610.6KCNQ1, KCNE1L, CAV3
23regulation of membrane repolarizationGO:06030610.6KCNQ1, KCNH2, KCNE2, KCNE1L, KCNJ2
24potassium ion importGO:01010710.6KCNJ2, KCNE2
25regulation of ventricular cardiac muscle cell membrane depolarizationGO:06037310.5SCN5A, CAV3
26potassium ion exportGO:07143510.5KCNE1L, KCNE2, KCNH2, KCNE1, KCNQ1, KCND3
27potassium ion transmembrane transportGO:07180510.5KCNQ1, KCNE1, KCNH2, KCNE2, KCNE1L, KCNJ2
28regulation of heart rateGO:00202710.5CAV3, SCN5A, SNTA1, ANK2, MYH7, RYR2
29cellular response to epinephrine stimulusGO:07187210.5KCNQ1, RYR2
30regulation of cardiac muscle cell contractionGO:08600410.5ANK2, SCN5A
31cardiac muscle contractionGO:06004810.5KCNQ1, KCNH2, KCNE1L, SCN5A, SCN4B, ANK2
32regulation of sodium ion transmembrane transporter activityGO:200064910.4CAV3, SCN4B
33synaptic transmissionGO:00726810.4KCND2, KCND3, KCNJ5, KCNQ1, KCNH2, KCNJ2
34regulation of heart rate by cardiac conductionGO:08609110.4ANK2, SCN4B, SCN5A, KCNJ2, KCNE1L, KCNE2
35positive regulation of sodium ion transportGO:01076510.4SCN4B, SCN5A
36regulation of ventricular cardiac muscle cell membrane repolarizationGO:06030710.3ANK2, SNTA1, SCN4B, SCN5A, CAV3, KCNE1L
37regulation of ventricular cardiac muscle cell action potentialGO:08600510.3KCNQ1, KCNE1, KCNH2, KCNE2, KCNE1L, CAV3
38potassium ion transportGO:00681310.3KCNJ2, KCNJ5, KCND3
39sodium ion transmembrane transportGO:03572510.3SCN5A, SCN4B
40regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionGO:01088110.0ANK2, RYR2

Molecular functions related to Long Qt Syndrome according to GeneCards/GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationGO:190228210.6KCNQ1, KCNE1, KCNH2, KCNE2
2nitric-oxide synthase bindingGO:05099810.5SNTA1, SCN5A, CAV3
3voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarizationGO:08600810.5KCNQ1, KCNE1, KCNE1L, KCNJ2
4inward rectifier potassium channel activityGO:00524210.5KCNJ2, KCNE2, KCNH2, KCNJ5
5voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potentialGO:08600610.5SCN4B, SCN5A
6A-type (transient outward) potassium channel activityGO:00525010.5KCND2, KCND3
7sodium channel regulator activityGO:01708010.5SNTA1, SCN4B, CAV3
8potassium channel regulator activityGO:01545910.5KCNE1, KCNE2, KCNE1L, ANK2
9voltage-gated potassium channel activityGO:00524910.4KCND2, KCNQ1, KCNE1, KCNH2, KCNE1L
10delayed rectifier potassium channel activityGO:00525110.4KCND2, KCND3, KCNQ1, KCNE1, KCNH2, KCNE2
11transferase activity, transferring hexosyl groupsGO:01675810.4ALG10B, ALG10
12calmodulin bindingGO:00551610.4KCNQ1, SCN5A, SNTA1, MYH7, RYR2
13protein kinase A regulatory subunit bindingGO:03423710.3RYR2, KCNQ1
14protein kinase A catalytic subunit bindingGO:03423610.2RYR2, KCNQ1
15ion channel bindingGO:04432510.1RYR2, KCND3, KCNQ1, KCNE2, KCNE1L, CAV3
16voltage-gated sodium channel activityGO:00524810.1SCN5A, SCN4B
17protein bindingGO:0055159.7KCNJ5, KCNQ1, KCNE1, KCNH2, CAV3, SCN5A

Products for genes affiliated with Long Qt Syndrome

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Long Qt Syndrome

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet