LQT
MCID: LNG028
MIFTS: 61

Long Qt Syndrome (LQT) malady

Summaries for Long Qt Syndrome

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8Disease Ontology, 42NIH Rare Diseases, 63Wikipedia, 46OMIM, 19GeneReviews, 32MalaCards
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NIH Rare Diseases:42 Long qt syndrome is a disorder of the heart’s electrical activity that can cause sudden, uncontrollable, and irregular heartbeats (arrhythmia), which may lead to sudden death. long qt syndrome can be detected by electrocardiogram (ekg). it can be caused by a variety of different gene mutations (changes). it can also be acquired (noninherited) and may be brought on by certain medicines and other medical conditions. last updated: 10/4/2013

MalaCards: Long Qt Syndrome, also known as romano-ward syndrome, is related to brugada syndrome and long qt syndrome 1. An important gene associated with Long Qt Syndrome is SCN5A (sodium channel, voltage-gated, type V, alpha subunit), and among its related pathways are Gastric acid secretion and Potassium transporters: inward current. The compounds chromanol and clofilium have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and brain, and related mouse phenotypes are homeostasis/metabolism and cardiovascular system.

Disease Ontology:8 An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (tdp, a form of irregular heartbeat that originates from the ventricles).

Wikipedia:63 Long QT syndrome (LQTS) is a rare inherited heart condition in which delayed repolarization of the heart... more...

Description from OMIM:46 611818, 603830, 613688, 613485, 612955 611819, 613695, 192500, 601005, 613693, 170390, 611820 more

GeneReviews summary for rws

Aliases & Classifications for Long Qt Syndrome

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 20GeneTests, 22GTR, 19GeneReviews, 46OMIM, 56SNOMED-CT, 27ICD9CM, 39NCIt, 34MeSH
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Aliases & Descriptions:

long qt syndrome 8 42 10 44 60
romano-ward syndrome 8 19 60
long q-t syndrome 8 20 22
long qt syndrome, autosomal dominant 19
romano-ward long qt syndrome 19
lqt 8


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Disease Ontology8 DOID:2843
ICD9CM27 426.82
NCIt39 C34786
MeSH34 D008133

Related Diseases for Long Qt Syndrome

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17GeneCards, 18GeneDecks
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Diseases in the Long Qt Syndrome 1 family:

long qt syndrome Long Qt Syndrome 10
Long Qt Syndrome 11 Long Qt Syndrome 2
Long Qt Syndrome 3 Long Qt Syndrome 4
Long Qt Syndrome 5 Long Qt Syndrome 6
Long Qt Syndrome 8 Long Qt Syndrome 9
Long Qt Syndrome 12 Long Qt Syndrome 13
Long Qt Syndrome-2, Acquired Long Qt Syndrome 1, Acquired

Diseases related to Long Qt Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 85)
idRelated DiseaseScoreTop Affiliating Genes
1brugada syndrome31.0KCNH2, KCNE2, KCNE1L, SCN5A, SCN4B, ANK2
2long qt syndrome 130.9KCNE1, KCNQ1, KCNH2, KCNE2, SCN5A
3atrioventricular block30.9KCNH2, SCN5A
4sudden infant death syndrome30.9CAV3, SCN5A
5jervell-lange nielsen syndrome30.8KCNE1, KCNQ1
6epilepsy syndrome30.7KCNH2, KCNQ1, ZACN, KCNJ5
7catecholaminergic polymorphic ventricular tachycardia30.7RYR2
8timothy syndrome30.7KCNE1, SCN4B
9sudden cardiac death multi-gene panels30.4RYR2, MYH7, ANK2, SCN5A, KCNJ2, KCNH2
10familial atrial fibrillation30.3SCN5A, KCNQ1, KCNE2
11congenital heart defect30.1KCNQ1, RYR2, KCNJ2
12andersen-tawil syndrome10.5
13long qt syndrome 310.5
14hypertrophic cardiomyopathy10.5
15short qt syndrome10.5
16long qt syndrome 1110.5
17long qt syndrome 210.5
18long qt syndrome 510.5
19long qt syndrome 610.5
20long qt syndrome 910.5
21long qt syndrome 1210.5
22long qt syndrome 1310.5
23syndactyly10.5
24n syndrome10.5
25long qt syndrome 1010.5
26long qt syndrome 410.5
27long qt syndrome 810.5
28scn5a-related romano ward syndrome10.4
29hypokalemia10.3
30dilated cardiomyopathy10.3
31epiphyseal dysplasia multiple with early-onset diabetes mellitus10.3
32kearns-sayre syndrome10.2
33beckwith-wiedemann syndrome10.2
34tetralogy of fallot10.2
35familial hypertrophic cardiomyopathy10.2
36adult syndrome10.2
37williams syndrome10.2
38long qt syndrome 1, acquired10.2
39acquired long qt syndrome, reduced10.2
40right bundle branch block10.1
41marfan syndrome10.1
42supravalvular aortic stenosis10.1
43primary hyperparathyroidism10.1
44hypoparathyroidism10.1
45arrhythmogenic right ventricular dysplasia10.1
46congenital generalized lipodystrophy10.1
47panhypopituitarism10.1
48hemochromatosis10.1
49pain disorder10.1
50conduct disorder10.1

Graphical network of the top 20 diseases related to Long Qt Syndrome:



Diseases related to long qt syndrome

Clinical Features for Long Qt Syndrome

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46OMIM
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Clinical features from OMIM:

611818, 603830, 613688, 613485, 612955, 611819, 613695, 192500, 601005, 613693 170390, 611820 more

Drugs & Therapeutics for Long Qt Syndrome

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Long Qt Syndrome

Drug clinical trials:

Search ClinicalTrials for Long Qt Syndrome

Search NIH Clinical Center for Long Qt Syndrome

Search CenterWatch for Long Qt Syndrome

Genetic Tests for Long Qt Syndrome

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20GeneTests, 22GTR
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Genetic tests related to Long Qt Syndrome:

id Genetic test Affiliating Genes
1 Long Qt Syndrome Multi-Gene Panels20
2 Long Qt Syndrome22

Anatomical Context for Long Qt Syndrome

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32MalaCards
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MalaCards organs/tissues related to Long Qt Syndrome:

32
Heart, Testes, Brain, Eye

Animal Models for Long Qt Syndrome or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Long Qt Syndrome:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053769.9KCNE2, RYR2, ANK2, AKAP9, CAV3, KCNJ2
2MP:00053859.8RYR2, KCND3, KCNJ5, KCNQ1, KCNE1, KCNH2
3MP:00053699.8SNTA1, SCN5A, CAV3, KCNJ2, KCNH2, RYR2

Publications for Long Qt Syndrome

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50PubMed
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Articles related to Long Qt Syndrome:

(show top 50)    (show all 843)
idTitleAuthorsYear
1
Congenital long QT syndrome with compound mutations in the KCNH2 gene. (24057343)
2013
2
The interaction of caveolin 3 protein with the potassium inward rectifier channel Kir2.1: physiology and pathology related to long qt syndrome 9 (LQT9). (23640888)
2013
3
Left thoracoscopic sympathectomy used as primary therapy for a young child with intractable long QT syndrome. (23011192)
2013
4
Novel deletion mutation in the cardiac sodium channel inactivation gate causes long QT syndrome. (22980924)
2013
5
Sex hormones and cardiac arrest in long QT syndrome: does progesterone represent a potential new antiarrhythmic therapy? (22381742)
2012
6
Fetal and neonatal presentation of long QT syndrome. (21401653)
2012
7
Not all beta-blockers are equal in the management of long QT syndrome types 1 and 2: higher recurrence of events under metoprolol. (23083782)
2012
8
Fetal heart rate predictors of long QT syndrome. (23124029)
2012
9
Acquired long QT syndrome: as risky as congenital long QT syndrome? (22106361)
2012
10
Long QT syndrome and dilated cardiomyopathy with SCN5A p.R1193Q polymorphism: cardioverter-defibrillator implantation at 27 months. (22519808)
2012
11
Successful elimination of significant arrhythmia burden with flecainide in an adolescent with long QT syndrome type 3. (22129298)
2012
12
Selective acquired long QT syndrome (saLQTS) upon risperidone treatment. (23216910)
2012
13
Letter by Van Laecke and Vanholder regarding article, "Risk of recurrent cardiac events after onset of menopause in women with congenital long-QT syndrome types 1 and 2". (22215897)
2012
14
Genetic testing of patients with long QT syndrome. (21216356)
2011
15
Inappropriate pacing inhibition triggered by QT prolongation due to T wave oversensing in an ICD recipient presenting with long QT syndrome. (21532225)
2011
16
Modelling long QT syndrome with iPS cells: be still, my beating heart ... (21415406)
2011
17
Abnormal repolarization dynamics revealed in exercise test in long QT syndrome mutation carriers with normal resting QT interval. (20566482)
2010
18
Two automatic QT algorithms compared with manual measurement in identification of long QT syndrome. (20005993)
2010
19
Mutations at KCNQ1 and an unknown locus cause long QT syndrome in a large Australian family: implications for genetic testing. (20186784)
2010
20
Posthumous diagnosis of long QT syndrome from neonatal screening cards. (20167303)
2010
21
Triggers for cardiac events in patients with type 2 long QT syndrome. (20887809)
2010
22
Molecular determinants of local anesthetic action of beta-blocking drugs: Implications for therapeutic management of long QT syndrome variant 3. (19481549)
2010
23
Takotsubo cardiomyopathy and congenital long QT syndrome in a patient with a novel duplication in the Per-Arnt-Sim (PAS) domain of hERG1. (20004623)
2010
24
Long QT syndrome. Don't forget antipsychotics. (20179110)
2010
25
Clinical implications for patients with long QT syndrome who experience a cardiac event during infancy. (19695463)
2009
26
Catheter ablation of a posteroseptal accessory pathway in a case with congenital long QT syndrome. (19367035)
2009
27
Long QT syndrome in children with congenital deafness. (19213984)
2009
28
Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome. (19306396)
2009
29
Neural control of heart rate is an arrhythmia risk modifier in long QT syndrome. (18308161)
2008
30
A missense mutation (G604S) in the S5/pore region of HERG causes long QT syndrome in a Chinese family with a high incidence of sudden unexpected death. (17171344)
2007
31
Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome. (17576861)
2007
32
Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene. (17292394)
2007
33
Long-QT syndrome-related sodium channel mutations probed by the dynamic action potential clamp technique. (16254012)
2006
34
Allelic dropout in long QT syndrome genetic testing: a possible mechanism underlying false-negative results. (16818214)
2006
35
Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome. (16361248)
2006
36
Novel mutations of potassium channel KCNQ1 S145L and KCNH2 Y475C genes in Chinese pedigrees of long QT syndrome]. (16831322)
2006
37
Pentamidine-induced long QT syndrome and block of hERG trafficking. (15340016)
2005
38
Mutation analysis of a Chinese family with inherited long QT syndrome]. (15696484)
2005
39
Denaturing high-performance liquid chromatography screening of the long QT syndrome-related cardiac sodium and potassium channel genes and identification of novel mutations and single nucleotide polymorphisms. (16155735)
2005
40
A novel SCN5A mutation manifests as a malignant form of long QT syndrome with perinatal onset of tachycardia/bradycardia. (15485686)
2004
41
Identification of a common genetic substrate underlying postpartum cardiac events in congenital long QT syndrome. (15851119)
2004
42
A candidate locus approach identifies a long QT syndrome gene mutation. (14531214)
2003
43
Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel. (11304498)
2001
44
Molecular biology and cellular mechanisms of Brugada and long QT syndromes in infants and young children. (11781953)
2001
45
Bradycardia-induced long QT syndrome caused by a de novo missense mutation in the S2-S3 inner loop of HERG. (11170080)
2001
46
Endoscopic resection of the thoracic sympathetic trunk for the treatment of frequent syncopal attack of idiopathic long QT syndrome]. (10339940)
1999
47
Swimming, a gene-specific arrhythmogenic trigger for inherited long QT syndrome. (10560595)
1999
48
Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel. (9495298)
1998
49
Effects of sodium channel block with mexiletine to reverse action potential prolongation in in vitro models of the long term QT syndrome. (9395171)
1997
50
Two long QT syndrome loci map to chromosomes 3 and 7 with evidence for further heterogeneity. (7842012)
1994

Genetic Variations for Long Qt Syndrome

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Expression for genes affiliated with Long Qt Syndrome

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Long Qt Syndrome

Search GEO for disease gene expression data for Long Qt Syndrome.

Pathways for genes affiliated with Long Qt Syndrome

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29KEGG, 12EMD Millipore, 37NCBI BioSystems Database, 53Reactome, 51QIAGEN, 49PharmGKB
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Compounds for genes affiliated with Long Qt Syndrome

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44Novoseek, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 49PharmGKB, 24HMDB
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Compounds related to Long Qt Syndrome according to GeneCards/GeneDecks:

(show all 41)
idCompoundScoreTop Affiliating Genes
1chromanol4410.8KCNE1, KCNQ1
2clofilium44 2811.7KCNQ1, KCNH2
3indapamide44 1111.7KCNE1, KCNQ1
4chromanol 293b44 59 2812.7KCNE1, KCNQ1
5Dalfampridine 1110.7KCND2, KCND3
6mexiletine44 1111.7KCNH2, SCN5A
7flecainide44 49 28 1113.7SCN5A, KCNH2, KCND2
8propafenone44 49 28 1113.7KCNH2, SCN5A
9katp4410.7KCNH2, KCNQ1, KCNJ5
10isoleucine4410.7KCNQ1, KCNH2, SCN5A
11pip22810.7KCNQ1, KCNJ5
12qx 314 chloride5910.7SCN5A, SCN4B
13glibenclamide44 28 49 5913.7KCNJ5, KCNQ1, KCNJ2
14cromakalim44 2811.6KCNQ1, KCNJ5
15tetrodotoxin citrate5910.6SCN5A, SCN4B
16tetraethylammonium44 28 1112.6KCNJ5, KCNQ1, KCNH2, KCNJ2
17phrixotoxin 35910.6SCN5A, SCN4B
18disopyramide44 1111.6KCND2, KCND3, KCNJ5, SCN5A
19ryanodine44 28 5912.6ANK2, MYH7, RYR2
20p10755910.6KCNJ5, KCNJ2
21levcromakalim5910.5KCNJ5, KCNJ2
22e-4031 dihydrochloride5910.5KCNQ1, KCNE1, KCNH2, KCNE2, KCND3, KCND2
23xe 991 dihydrochloride5910.5KCND2, KCND3, KCNQ1, KCNE1, KCNE2, KCNH2
24jnj 3035910.5KCNE2, KCNH2, KCNE1, KCNQ1, KCND3, KCND2
25shk-dap225910.5KCNE2, KCNH2, KCNE1, KCNQ1, KCND3, KCND2
26ica 1103815910.5KCNE2, KCNH2, KCNE1, KCNQ1, KCND3, KCND2
27tertiapin-q5910.5KCNJ5, KCNJ2
28veratridine44 59 2812.5SCN5A, SCN4B
29arginine4410.5KCNQ1, KCNE1, KCNH2, KCNJ2, SCN5A, MYH7
30isoproterenol44 1111.5KCNQ1, KCNH2, KCNJ2, CAV3, MYH7, RYR2
31bepridil44 28 1112.5KCNQ1, KCNH2
32phospholipid4410.5KCNJ5, KCNE1, KCNH2, RYR2
33charybdotoxin44 2811.4KCNJ5, KCNQ1
34lipid4410.4KCND3, KCNJ5, KCNE1, KCNH2, CAV3, MYH7
35mg2+2810.3RYR2, KCNJ2
36verapamil44 49 28 11 2414.2KCNH2, SCN5A, RYR2
37sodium44 2411.2RYR2, KCNJ5, MYH7, ZACN, SNTA1, SCN4B
38nitric oxide44 11 2412.2RYR2, SNTA1, CAV3, KCNE1, KCNJ5
39potassium44 11 2412.1AKAP9, SCN5A, KCNJ2, KCNE2, KCNH2, KCNE1
40calcium44 49 11 2413.1KCND3, KCNJ5, KCNQ1, KCNH2, KCNJ2, CAV3
41cisapride44 28 1112.1SCN5A, KCNH2

GO Terms for genes affiliated with Long Qt Syndrome

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16Gene Ontology
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Cellular components related to Long Qt Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel complexGO:00151810.4SCN4B, SCN5A
2sarcolemmaGO:04238310.3KCND3, KCNQ1, CAV3, SCN5A, SNTA1, ANK2
3Z discGO:03001810.2KCNE1, CAV3, ANK2, MYH7, RYR2
4T-tubuleGO:03031510.2CAV3, SCN5A, ANK2
5cell surfaceGO:00998610.1KCND2, KCNE1, KCNH2, KCNE2, CAV3, SCN5A
6intercalated discGO:01470410.0ANK2, SCN4B, SCN5A
7voltage-gated potassium channel complexGO:00807610.0AKAP9, KCND2, KCND3, KCNJ5, KCNQ1, KCNE1
8plasma membraneGO:0058869.7KCNH2, KCNE1, KCNQ1, KCNJ5, KCND3, KCND2

Biological processes related to Long Qt Syndrome according to GeneCards/GeneDecks:

(show all 40)
idNameGO IDScoreTop Affiliating Genes
1regulation of delayed rectifier potassium channel activityGO:190225910.7KCNE1, KCNE2
2membrane depolarization involved in regulation of SA node cell action potentialGO:08604610.7SCN5A, ANK2
3regulation of calcium ion transmembrane transporter activityGO:190101910.7CAV3, ANK2
4T-tubule organizationGO:03329210.7CAV3, ANK2
5SA node cell to atrial cardiac muscle cell communicationGO:08607010.7ANK2, SCN5A
6membrane depolarization involved in regulation of cardiac muscle cell action potentialGO:08601210.7SCN4B, SCN5A, KCNJ2
7membrane repolarizationGO:08600910.7KCND3, KCNE1, KCNE2
8negative regulation of potassium ion transmembrane transportGO:190138010.7KCNH2, KCNE1L, CAV3
9regulation of atrial cardiac muscle cell membrane repolarizationGO:06037210.7KCNQ1, KCNE1L, SCN5A
10membrane repolarization involved in regulation of cardiac muscle cell action potentialGO:08601310.7KCNQ1, KCNE1, KCNH2, KCNJ2
11membrane depolarization involved in regulation of action potentialGO:08601010.6SCN5A, KCNH2
12regulation of atrial cardiac muscle cell action potentialGO:08601410.6KCNQ1, KCNE1L, ANK2
13positive regulation of potassium ion transmembrane transportGO:190138110.6KCNQ1, KCNE1, KCNH2, KCNE1L
14AV node cell to bundle of His cell communicationGO:08606710.6SCN4B, SCN5A
15regulation of cardiac muscle contractionGO:05511710.6RYR2, ANK2, CAV3
16regulation of potassium ion transmembrane transportGO:190137910.6KCNE1, KCNH2, KCNE2, KCNE1L
17membrane repolarization involved in regulation of action potentialGO:08601110.6KCNQ1, KCNE1, KCNH2, KCNE2, KCNJ2
18regulation of cardiac muscle cell action potential involved in contractionGO:08600210.6KCNE1, KCNE2, KCNJ2, SCN5A, SCN4B
19cellular response to drugGO:03569010.6KCNQ1, KCNH2, KCNE2
20regulation of sodium ion transmembrane transportGO:190230510.6SCN5A, SNTA1
21sarcoplasmic reticulum calcium ion transportGO:07029610.6RYR2, ANK2
22regulation of heart contractionGO:00801610.6KCNQ1, KCNE1L, CAV3
23regulation of membrane repolarizationGO:06030610.6KCNQ1, KCNH2, KCNE2, KCNE1L, KCNJ2
24potassium ion importGO:01010710.6KCNJ2, KCNE2
25regulation of ventricular cardiac muscle cell membrane depolarizationGO:06037310.5SCN5A, CAV3
26potassium ion exportGO:07143510.5KCNE1L, KCNE2, KCNH2, KCNE1, KCNQ1, KCND3
27potassium ion transmembrane transportGO:07180510.5KCNQ1, KCNE1, KCNH2, KCNE2, KCNE1L, KCNJ2
28regulation of heart rateGO:00202710.5CAV3, SCN5A, SNTA1, ANK2, MYH7, RYR2
29cellular response to epinephrine stimulusGO:07187210.5KCNQ1, RYR2
30regulation of cardiac muscle cell contractionGO:08600410.5ANK2, SCN5A
31cardiac muscle contractionGO:06004810.5KCNQ1, KCNH2, KCNE1L, SCN5A, SCN4B, ANK2
32regulation of sodium ion transmembrane transporter activityGO:200064910.4CAV3, SCN4B
33synaptic transmissionGO:00726810.4KCND2, KCND3, KCNJ5, KCNQ1, KCNH2, KCNJ2
34regulation of heart rate by cardiac conductionGO:08609110.4ANK2, SCN4B, SCN5A, KCNJ2, KCNE1L, KCNE2
35positive regulation of sodium ion transportGO:01076510.4SCN4B, SCN5A
36regulation of ventricular cardiac muscle cell membrane repolarizationGO:06030710.3ANK2, SNTA1, SCN4B, SCN5A, CAV3, KCNE1L
37regulation of ventricular cardiac muscle cell action potentialGO:08600510.3KCNQ1, KCNE1, KCNH2, KCNE2, KCNE1L, CAV3
38potassium ion transportGO:00681310.3KCNJ2, KCNJ5, KCND3
39sodium ion transmembrane transportGO:03572510.3SCN5A, SCN4B
40regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionGO:01088110.0ANK2, RYR2

Molecular functions related to Long Qt Syndrome according to GeneCards/GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationGO:190228210.6KCNQ1, KCNE1, KCNH2, KCNE2
2nitric-oxide synthase bindingGO:05099810.5SNTA1, SCN5A, CAV3
3voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarizationGO:08600810.5KCNQ1, KCNE1, KCNE1L, KCNJ2
4inward rectifier potassium channel activityGO:00524210.5KCNJ2, KCNE2, KCNH2, KCNJ5
5voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potentialGO:08600610.5SCN4B, SCN5A
6A-type (transient outward) potassium channel activityGO:00525010.5KCND2, KCND3
7sodium channel regulator activityGO:01708010.5SNTA1, SCN4B, CAV3
8potassium channel regulator activityGO:01545910.5KCNE1, KCNE2, KCNE1L, ANK2
9voltage-gated potassium channel activityGO:00524910.4KCND2, KCNQ1, KCNE1, KCNH2, KCNE1L
10delayed rectifier potassium channel activityGO:00525110.4KCND2, KCND3, KCNQ1, KCNE1, KCNH2, KCNE2
11transferase activity, transferring hexosyl groupsGO:01675810.4ALG10B, ALG10
12calmodulin bindingGO:00551610.4KCNQ1, SCN5A, SNTA1, MYH7, RYR2
13protein kinase A regulatory subunit bindingGO:03423710.3RYR2, KCNQ1
14protein kinase A catalytic subunit bindingGO:03423610.2RYR2, KCNQ1
15ion channel bindingGO:04432510.1RYR2, KCND3, KCNQ1, KCNE2, KCNE1L, CAV3
16voltage-gated sodium channel activityGO:00524810.1SCN5A, SCN4B
17protein bindingGO:0055159.7KCNJ5, KCNQ1, KCNE1, KCNH2, CAV3, SCN5A

Products for genes affiliated with Long Qt Syndrome

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Sources for Long Qt Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet