MCID: LRR001
MIFTS: 18

Lrrk2-Related Parkinson Disease malady

Categories: Genetic diseases, Neuronal diseases, Mental diseases, Rare diseases, Metabolic diseases

Aliases & Classifications for Lrrk2-Related Parkinson Disease

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Aliases & Descriptions for Lrrk2-Related Parkinson Disease:

Name: Lrrk2-Related Parkinson Disease 23 24
Lrrk2-Associated Parkinson Disease 23 24
Parkinson Disease 8 24 67
 
Park 8 24
Park8 23

Characteristics:

GeneReviews:

23
Penetrance: penetrance of lrrk2 pathogenic variants is age dependent but may vary depending on pathogenic variant and population ethnicity. ...


Classifications:



Summaries for Lrrk2-Related Parkinson Disease

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MalaCards based summary: Lrrk2-Related Parkinson Disease, also known as lrrk2-associated parkinson disease, is related to parkinson disease, late-onset and parkinson disease 8, and has symptoms including muscle rigidity, bradykinesia and sense of smell impaired. An important gene associated with Lrrk2-Related Parkinson Disease is LRRK2 (Leucine Rich Repeat Kinase 2). Affiliated tissues include colon.

GeneReviews for NBK1208

Related Diseases for Lrrk2-Related Parkinson Disease

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Symptoms for Lrrk2-Related Parkinson Disease

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UMLS symptoms related to Lrrk2-Related Parkinson Disease:


muscle rigidity, bradykinesia, sense of smell impaired

Drugs & Therapeutics for Lrrk2-Related Parkinson Disease

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Drugs for Lrrk2-Related Parkinson Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1ColaNutraceutical1881

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study of the Enteric Nervous System Using Colonic Biopsies in Parkinson Patients With LRRK2 MutationTerminatedNCT01618383

Search NIH Clinical Center for Lrrk2-Related Parkinson Disease

Genetic Tests for Lrrk2-Related Parkinson Disease

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Genetic tests related to Lrrk2-Related Parkinson Disease:

id Genetic test Affiliating Genes
1 Lrrk2-Related Parkinson Disease24 LRRK2

Anatomical Context for Lrrk2-Related Parkinson Disease

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MalaCards organs/tissues related to Lrrk2-Related Parkinson Disease:

35
Colon

Animal Models for Lrrk2-Related Parkinson Disease or affiliated genes

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Publications for Lrrk2-Related Parkinson Disease

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Articles related to Lrrk2-Related Parkinson Disease:

idTitleAuthorsYear
1
Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease. (25401511)
2014
2
LRRK2-Related Parkinson Disease (20301387)
1993

Variations for Lrrk2-Related Parkinson Disease

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Expression for genes affiliated with Lrrk2-Related Parkinson Disease

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Search GEO for disease gene expression data for Lrrk2-Related Parkinson Disease.

Pathways for genes affiliated with Lrrk2-Related Parkinson Disease

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GO Terms for genes affiliated with Lrrk2-Related Parkinson Disease

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Sources for Lrrk2-Related Parkinson Disease

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet