MCID: LRR001
MIFTS: 18

Lrrk2-Related Parkinson Disease malady

Categories: Genetic diseases, Neuronal diseases, Mental diseases, Rare diseases, Metabolic diseases

Aliases & Classifications for Lrrk2-Related Parkinson Disease

About this section

Aliases & Descriptions for Lrrk2-Related Parkinson Disease:

Name: Lrrk2-Related Parkinson Disease 23 24
Lrrk2-Associated Parkinson Disease 23 24
Parkinson Disease 8 24 68
 
Park 8 24
Park8 23

Characteristics:

GeneReviews:

23
Penetrance: penetrance of lrrk2 pathogenic variants is age dependent but may vary depending on pathogenic variant and population ethnicity. ...


Classifications:



Summaries for Lrrk2-Related Parkinson Disease

About this section
MalaCards based summary: Lrrk2-Related Parkinson Disease, also known as lrrk2-associated parkinson disease, is related to parkinson disease, late-onset and parkinson disease 8, and has symptoms including muscle rigidity, bradykinesia and sense of smell impaired. An important gene associated with Lrrk2-Related Parkinson Disease is LRRK2 (Leucine Rich Repeat Kinase 2). Affiliated tissues include colon.

GeneReviews for NBK1208

Related Diseases for Lrrk2-Related Parkinson Disease

About this section

Symptoms & Phenotypes for Lrrk2-Related Parkinson Disease

About this section

UMLS symptoms related to Lrrk2-Related Parkinson Disease:


muscle rigidity, bradykinesia, sense of smell impaired

Drugs & Therapeutics for Lrrk2-Related Parkinson Disease

About this section

Drugs for Lrrk2-Related Parkinson Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1ColaNutraceutical1881

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study of the Enteric Nervous System Using Colonic Biopsies in Parkinson Patients With LRRK2 MutationTerminatedNCT01618383

Search NIH Clinical Center for Lrrk2-Related Parkinson Disease

Genetic Tests for Lrrk2-Related Parkinson Disease

About this section

Genetic tests related to Lrrk2-Related Parkinson Disease:

id Genetic test Affiliating Genes
1 Lrrk2-Related Parkinson Disease24 LRRK2

Anatomical Context for Lrrk2-Related Parkinson Disease

About this section

MalaCards organs/tissues related to Lrrk2-Related Parkinson Disease:

36
Colon

Publications for Lrrk2-Related Parkinson Disease

About this section

Articles related to Lrrk2-Related Parkinson Disease:

idTitleAuthorsYear
1
Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease. (25401511)
2014
2
LRRK2-Related Parkinson Disease (20301387)
1993

Variations for Lrrk2-Related Parkinson Disease

About this section

Expression for genes affiliated with Lrrk2-Related Parkinson Disease

About this section
Search GEO for disease gene expression data for Lrrk2-Related Parkinson Disease.

Pathways for genes affiliated with Lrrk2-Related Parkinson Disease

About this section

GO Terms for genes affiliated with Lrrk2-Related Parkinson Disease

About this section

Sources for Lrrk2-Related Parkinson Disease

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet