PARK8
MCID: LRR001
MIFTS: 17

Lrrk2-Related Parkinson Disease (PARK8) malady

Categories: Genetic diseases, Neuronal diseases, Mental diseases, Rare diseases, Metabolic diseases

Aliases & Classifications for Lrrk2-Related Parkinson Disease

Aliases & Descriptions for Lrrk2-Related Parkinson Disease:

Name: Lrrk2-Related Parkinson Disease 23 24
Lrrk2-Associated Parkinson Disease 23 24
Parkinson Disease 8 24 69
Park 8 24
Park8 23

Characteristics:

GeneReviews:

23
Penetrance Penetrance of lrrk2 pathogenic variants is age dependent but may vary depending on pathogenic variant and population ethnicity. ...

Classifications:



Summaries for Lrrk2-Related Parkinson Disease

MalaCards based summary : Lrrk2-Related Parkinson Disease, also known as lrrk2-associated parkinson disease, is related to parkinson disease 8 and parkinson disease, late-onset, and has symptoms including muscle rigidity, bradykinesia and hyposmia. An important gene associated with Lrrk2-Related Parkinson Disease is LRRK2 (Leucine Rich Repeat Kinase 2). The drug Cola has been mentioned in the context of this disorder.

GeneReviews: NBK1208

Related Diseases for Lrrk2-Related Parkinson Disease

Symptoms & Phenotypes for Lrrk2-Related Parkinson Disease

UMLS symptoms related to Lrrk2-Related Parkinson Disease:


muscle rigidity, bradykinesia, hyposmia

Drugs & Therapeutics for Lrrk2-Related Parkinson Disease

Drugs for Lrrk2-Related Parkinson Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Cola Nutraceutical

Interventional clinical trials:


id Name Status NCT ID Phase
1 Study of the Enteric Nervous System Using Colonic Biopsies in Parkinson Patients With LRRK2 Mutation Terminated NCT01618383

Search NIH Clinical Center for Lrrk2-Related Parkinson Disease

Genetic Tests for Lrrk2-Related Parkinson Disease

Genetic tests related to Lrrk2-Related Parkinson Disease:

id Genetic test Affiliating Genes
1 Lrrk2-Related Parkinson Disease 24 LRRK2

Anatomical Context for Lrrk2-Related Parkinson Disease

Publications for Lrrk2-Related Parkinson Disease

Articles related to Lrrk2-Related Parkinson Disease:

id Title Authors Year
1
Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease. ( 25401511 )
2014
2
LRRK2-Related Parkinson Disease ( 20301387 )
1993

Variations for Lrrk2-Related Parkinson Disease

Expression for Lrrk2-Related Parkinson Disease

Search GEO for disease gene expression data for Lrrk2-Related Parkinson Disease.

Pathways for Lrrk2-Related Parkinson Disease

GO Terms for Lrrk2-Related Parkinson Disease

Sources for Lrrk2-Related Parkinson Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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