MCID: LCY001
MIFTS: 13

Lucey-Driscoll Syndrome malady

Categories: Genetic diseases, Rare diseases, Liver diseases

Aliases & Classifications for Lucey-Driscoll Syndrome

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Sources:
45NIH Rare Diseases, 51Orphanet, 24GTR, 65UMLS, 22GeneTests, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Lucey-Driscoll Syndrome:

Name: Lucey-Driscoll Syndrome 45 51 24 65
Transient Familial Neonatal Hyperbilirubinemia 45 22 51
 
Transient Familial Hyperbilirubinemia 45

Classifications:

Orphanet: 51 
Rare hepatic diseases


External Ids:

Orphanet51 2312
ICD10 via Orphanet28 P59.8
UMLS65 C0270210

Summaries for Lucey-Driscoll Syndrome

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NIH Rare Diseases:45 Lucey-driscoll syndrome, a form of transient familial hyperbilirubinemia, is a rare metabolic disorder that leads to very high levels of bilirubin in a newborn's blood. babies with this disorder may be born with severe jaundice (yellow skin), yellow eyes and lethargy. it occurs when the body does not properly break down (metabolize) a certain form of bilirubin.  if untreated, this condition can cause seizures, neurologic problems (kernicterus) and even death. treatment for lucey-driscoll syndrome includes phototherapy with blue light (to treat the high level of bilirubin in the blood) and an exchange transfusion is sometimes necessary. different inheritance patterns have been reported and in some cases, it occurs in individuals with no family history of the condition. last updated: 11/15/2010

MalaCards based summary: Lucey-Driscoll Syndrome, also known as transient familial neonatal hyperbilirubinemia, is related to hyperbilirubinemia, familial transient neonatal, and has symptoms including newborn physiological jaundiceand newborn physiological jaundice. An important gene associated with Lucey-Driscoll Syndrome is UGT1A1 (UDP Glucuronosyltransferase Family 1 Member A1). Affiliated tissues include skin, eye and liver.

Related Diseases for Lucey-Driscoll Syndrome

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Diseases related to Lucey-Driscoll Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1hyperbilirubinemia, familial transient neonatal11.5

Symptoms for Lucey-Driscoll Syndrome

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UMLS symptoms related to Lucey-Driscoll Syndrome:


newborn physiological jaundice

Drugs & Therapeutics for Lucey-Driscoll Syndrome

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Lucey-Driscoll Syndrome

Genetic Tests for Lucey-Driscoll Syndrome

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Anatomical Context for Lucey-Driscoll Syndrome

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MalaCards organs/tissues related to Lucey-Driscoll Syndrome:

33
Skin, Eye, Liver

Animal Models for Lucey-Driscoll Syndrome or affiliated genes

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Publications for Lucey-Driscoll Syndrome

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Variations for Lucey-Driscoll Syndrome

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Expression for genes affiliated with Lucey-Driscoll Syndrome

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Search GEO for disease gene expression data for Lucey-Driscoll Syndrome.

Pathways for genes affiliated with Lucey-Driscoll Syndrome

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GO Terms for genes affiliated with Lucey-Driscoll Syndrome

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Sources for Lucey-Driscoll Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet