MCID: LCY001
MIFTS: 13

Lucey-Driscoll Syndrome malady

Categories: Genetic diseases, Rare diseases

Aliases & Classifications for Lucey-Driscoll Syndrome

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Aliases & Descriptions for Lucey-Driscoll Syndrome:

Name: Lucey-Driscoll Syndrome 46 25 66
Transient Familial Neonatal Hyperbilirubinemia 46 23
 
Transient Familial Hyperbilirubinemia 46

Classifications:



Summaries for Lucey-Driscoll Syndrome

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NIH Rare Diseases:46 Lucey-driscoll syndrome, a form of transient familial hyperbilirubinemia, is a rare metabolic disorder that leads to very high levels of bilirubin in a newborn's blood. babies with this disorder may be born with severe jaundice (yellow skin), yellow eyes and lethargy. it occurs when the body does not properly break down (metabolize) a certain form of bilirubin.  if untreated, this condition can cause seizures, neurologic problems (kernicterus) and even death. treatment for lucey-driscoll syndrome includes phototherapy with blue light (to treat the high level of bilirubin in the blood) and an exchange transfusion is sometimes necessary. different inheritance patterns have been reported and in some cases, it occurs in individuals with no family history of the condition. last updated: 11/15/2010

MalaCards based summary: Lucey-Driscoll Syndrome, also known as transient familial neonatal hyperbilirubinemia, is related to hyperbilirubinemia, familial transient neonatal, and has symptoms including newborn physiological jaundice and newborn physiological jaundice. Affiliated tissues include skin and eye.

Related Diseases for Lucey-Driscoll Syndrome

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Diseases related to Lucey-Driscoll Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1hyperbilirubinemia, familial transient neonatal11.6

Symptoms for Lucey-Driscoll Syndrome

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UMLS symptoms related to Lucey-Driscoll Syndrome:


newborn physiological jaundice

Drugs & Therapeutics for Lucey-Driscoll Syndrome

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Lucey-Driscoll Syndrome

Genetic Tests for Lucey-Driscoll Syndrome

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Genetic tests related to Lucey-Driscoll Syndrome:

id Genetic test Affiliating Genes
1 Lucey-Driscoll Syndrome25

Anatomical Context for Lucey-Driscoll Syndrome

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MalaCards organs/tissues related to Lucey-Driscoll Syndrome:

34
Skin, Eye

Animal Models for Lucey-Driscoll Syndrome or affiliated genes

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Publications for Lucey-Driscoll Syndrome

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Variations for Lucey-Driscoll Syndrome

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Clinvar genetic disease variations for Lucey-Driscoll Syndrome:

5
id Gene Variation Type Significance SNP ID Assembly Location
1UGT1A1*6single nucleotide variantdrug responsers4148323GRCh37Chr 2, 234669144: 234669144

Expression for genes affiliated with Lucey-Driscoll Syndrome

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Search GEO for disease gene expression data for Lucey-Driscoll Syndrome.

Pathways for genes affiliated with Lucey-Driscoll Syndrome

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GO Terms for genes affiliated with Lucey-Driscoll Syndrome

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Sources for Lucey-Driscoll Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet