MCID: LNG029
MIFTS: 43

Lung Adenocarcinoma malady

Rare diseases, Cancer diseases, Respiratory diseases categories

Summaries for Lung Adenocarcinoma

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Wikipedia:64 Adenocarcinoma of the lung (pulmonary adenocarcinoma) is a common histological form of lung cancer that... more...

MalaCards based summary: Lung Adenocarcinoma, also known as adenocarcinoma of lung, is related to adenocarcinoma and lung cancer. An important gene associated with Lung Adenocarcinoma is KRAS (Kirsten rat sarcoma viral oncogene homolog), and among its related pathways is MicroRNAs in cancer. Affiliated tissues include lung, brain and endothelial.

Disease Ontology:9 A non-small cell lung carcinoma that derives from epithelial cells of glandular origin.

Aliases & Classifications for Lung Adenocarcinoma

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Lung Adenocarcinoma, Aliases & Descriptions:

Name: Lung Adenocarcinoma 31 9 42
Adenocarcinoma of Lung 42 61
Non-Small Cell Adenocarcinoma 61
 
Nonsmall Cell Adenocarcinoma 9
Adenocarcinoma Lung 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Respiratory diseases


External Ids:

Disease Ontology9 DOID:3910
MeSH34 C538231
SNOMED-CT56 254626006
NCIt39 C3512

Related Diseases for Lung Adenocarcinoma

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Diseases related to Lung Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 119)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma32.5NAPSA, XAGE1D, KRAS
2lung cancer31.1KRAS, NAPSA
3hypoxia10.6
4endotheliitis10.5
5thyroiditis10.5
6adenocarcinoma in situ10.4
7paraneoplastic syndromes10.3
8testicular cancer10.3KRAS, XAGE1D
9obstructive jaundice10.3
10esophagitis10.3
11meningitis10.3
12newcastle disease10.2
13interstitial lung disease10.2
14malignant mesothelioma10.2
15pneumothorax10.2
16sarcoma10.2
17adenocarcinoma of lung, somatic10.2
18adenocarcinoma of lung, response to tyrosine kinase inhibitor in10.2
19b-cell lymphomas10.1
20colorectal cancer10.1
21neuroendocrine carcinoma10.1
22adenoiditis10.1
23lambert-eaton myasthenic syndrome10.1
24xeroderma pigmentosum10.1
25actinomycosis10.1
26li-fraumeni syndrome10.1
27choroiditis10.1
28bronchogenic lung adenocarcinoma10.1
29dermatomyositis10.1
30melanoma10.1
31pancreatitis10.1
32pericardial effusion10.1
33prostatitis10.1
34papillary adenocarcinoma10.0
35polymorphous low-grade adenocarcinoma10.0
36rhabdoid tumor10.0
37anaplastic large cell lymphoma10.0
38ataxia telangiectasia10.0
39cervical cancer10.0
40gastric cancer10.0
41hepatocellular carcinoma10.0
42hydrocephalus10.0
43marginal zone b-cell lymphoma10.0
44multifocal motor neuropathy10.0
45prostate cancer10.0
46severe combined immunodeficiency10.0
47invasive aspergillosis10.0
48lung occult adenocarcinoma10.0
49maxillary sinus adenoid cystic carcinoma10.0
50myoma10.0

Graphical network of the top 20 diseases related to Lung Adenocarcinoma:



Diseases related to lung adenocarcinoma

Symptoms for Lung Adenocarcinoma

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Drugs & Therapeutics for Lung Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Lung Adenocarcinoma

Search NIH Clinical Center for Lung Adenocarcinoma

Genetic Tests for Lung Adenocarcinoma

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Anatomical Context for Lung Adenocarcinoma

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MalaCards organs/tissues related to Lung Adenocarcinoma:

32
Lung, Brain, Endothelial, Lymph node, Thyroid, Testes, Breast, T cells, Bone, Colon, Spinal cord, Prostate, Nk cells, B cells, Neutrophil, Bone marrow, Whole blood, Smooth muscle, Kidney, Skin, Placenta, Testis, Monocytes, Pineal

Animal Models for Lung Adenocarcinoma or affiliated genes

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Publications for Lung Adenocarcinoma

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Articles related to Lung Adenocarcinoma:

(show top 50)    (show all 1469)
idTitleAuthorsYear
1
TGF-I^ regulates the proliferation of lung adenocarcinoma cells by inhibiting PIK3R3 expression. (25371235)
2014
2
Psf3 is a prognostic biomarker in lung adenocarcinoma. (23127337)
2013
3
MicroRNA-98 sensitizes cisplatin-resistant human lung adenocarcinoma cells by up-regulation of HMGA2. (23700794)
2013
4
Clinical implications related to preoperative detection of stage IA lung adenocarcinoma. (23497951)
2013
5
Inducing cell proliferation inhibition, apoptosis, and motility reduction by silencing long noncoding ribonucleic acid metastasis-associated lung adenocarcinoma transcript 1 in urothelial carcinoma of the bladder. (23153939)
2013
6
Effect of TRAF6 on the biological behavior of human lung adenocarcinoma cell. (23055197)
2013
7
Network-based differential gene expression analysis suggests cell cycle related genes regulated by E2F1 underlie the molecular difference between smoker and non-smoker lung adenocarcinoma. (24341432)
2013
8
Ground glass opacity and T-factor in staging lung adenocarcinoma. (23242983)
2013
9
Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma. (22982652)
2012
10
Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma. (22302706)
2012
11
Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas. (22080568)
2012
12
Hypoxia upregulates the expression of annexin A1 in lung adenocarcinoma a549 cells]. (22613333)
2012
13
Activation of a Tip60/E2F1/ERCC1 network in human lung adenocarcinoma cells exposed to cisplatin. (22159227)
2012
14
Loss of DBC2 expression is an early and progressive event in the development of lung adenocarcinoma. (22901165)
2012
15
Effusion immunocytochemistry as an alternative approach for the selection of first-line targeted therapy in advanced lung adenocarcinoma. (22525557)
2012
16
High thymidine kinase 1 (TK1) expression is a predictor of poor survival in patients with pT1 of lung adenocarcinoma. (22143937)
2012
17
EGFR mutations predict a favorable outcome for malignant pleural effusion of lung adenocarcinoma with Tarceva therapy. (22134479)
2012
18
Expression of caveolin-1 is correlated with disease stage and survival in lung adenocarcinomas. (22200856)
2012
19
The relationship between EGFR gain and VHL loss in lung adenocarcinoma and poor patient survival. (21556796)
2011
20
Overexpression of gelsolin-like actin-capping protein is associated with progression of lung adenocarcinoma. (21908955)
2011
21
Combination of napsin A and TTF-1 immunohistochemistry helps in differentiating primary lung adenocarcinoma from metastatic carcinoma in the lung. (21464700)
2011
22
Comprehensive molecular analyses of lung adenocarcinoma with regard to the epidermal growth factor receptor, K-ras, MET, and hepatocyte growth factor status. (20150826)
2010
23
Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma. (20802348)
2010
24
Quantitative proteome analysis reveals annexin A3 as a novel biomarker in lung adenocarcinoma. (18798225)
2009
25
Prognostic value of KRAS mutations and Ki-67 expression in stage I lung adenocarcinomas. (19162366)
2009
26
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. (19576624)
2009
27
IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions. (19582164)
2009
28
Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma. (19040416)
2009
29
Effects of hydroquinone on expression of human 8-oxo-guanine DNA glycosylase mRNA in human A549 lung adenocarcinoma cell strains]. (19535000)
2009
30
ING4 induces cell growth inhibition in human lung adenocarcinoma A549 cells by means of Wnt-1/beta-catenin signaling pathway. (18399550)
2008
31
Lung adenocarcinoma with good response to erlotinib after gefitinib treatment failure and acquired T790M mutation. (18379370)
2008
32
Successful treatment of carcinomatous meningitis with gefitinib in a patient with lung adenocarcinoma harboring a mutated EGF receptor gene. (18441512)
2008
33
Correlation between lymph node metastasis and the expression of VEGF-C, VEGF-D and VEGFR-3 in T1 lung adenocarcinoma. (17970036)
2007
34
Molecular markers and changes of computed tomography appearance in lung adenocarcinoma with ground-glass opacity. (18089646)
2007
35
Gene expression profiling of epidermal growth factor receptor/KRAS pathway activation in lung adenocarcinoma. (17459062)
2007
36
Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas. (18060032)
2007
37
Effects of selenium supplementation on expression of glutathione peroxidase isoforms in cultured human lung adenocarcinoma cell lines. (17052796)
2007
38
Overexpression of Dicer in precursor lesions of lung adenocarcinoma. (17332367)
2007
39
HOXB2 as a novel prognostic indicator for stage I lung adenocarcinomas. (17805056)
2007
40
Immunohistochemical alpha- and beta-catenin and E-cadherin expression and their clinicopathological significance in human lung adenocarcinoma. (16843618)
2006
41
Dissimilarity in gene expression profiles of lung adenocarcinoma in Japanese men and women. (17081955)
2006
42
Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice. (15753363)
2005
43
Lung adenocarcinoma global profiling identifies type II transforming growth factor-beta receptor as a repressor of invasiveness. (15976377)
2005
44
Lung adenocarcinoma associated with familial adenomatous polyposis. Clear cell carcinoma with beta-catenin accumulation accompanied by atypical adenomatous hyperplasia. (15660284)
2005
45
Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway. (12896906)
2003
46
Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. Role for endogenous ceramide in mediating the action of exogenous ceramide. (11815611)
2002
47
Significant correlation of nitric oxide synthase activity and p53 gene mutation in stage I lung adenocarcinoma. (9738975)
1998
48
Involvement of tyrosine kinase activity in the low-density lipoprotein receptor expression in human lung adenocarcinoma cell line A549. (9116058)
1996
49
Genotypic, phenotypic and biological characterization of a novel human lung adenocarcinoma cell line (LC 89) (8196904)
1994
50
Overexpression of the p53 tumor suppressor gene product in primary lung adenocarcinomas is associated with cigarette smoking. (8434702)
1993

Variations for Lung Adenocarcinoma

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Expression for genes affiliated with Lung Adenocarcinoma

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets, 31LifeMap Discovery®
See all sources
LifeMap Discovery
Genes differentially expressed in tissues of Lung Adenocarcinoma patients vs. healthy controls: 31 (show all 342)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1TNNC1troponin C type 1 (slow)Lung-5.280.000
2COL11A1collagen, type XI, alpha 1Lung+5.070.000
3MMP1matrix metallopeptidase 1 (interstitial collagenase)Lung+4.750.000
4AGERadvanced glycosylation end product-specific receptorLung-4.690.000
5WIF1WNT inhibitory factor 1Lung-4.600.000
6SOSTDC1sclerostin domain containing 1Lung-4.470.000
7FABP4fatty acid binding protein 4, adipocyteLung-4.320.000
8CDH3cadherin 3, type 1, P-cadherin (placental)Lung+4.310.000
9FOSBFBJ murine osteosarcoma viral oncogene homolog BLung-4.240.000
10TMEM100transmembrane protein 100Lung-4.200.000
11CLEC3BC-type lectin domain family 3, member BLung-4.180.000
12FCN3ficolin (collagen/fibrinogen domain containing) 3Lung-4.170.000
13MT1Mmetallothionein 1MLung-4.070.000
14SPP1secreted phosphoprotein 1Lung+4.040.000
15SPINK1serine peptidase inhibitor, Kazal type 1Lung+3.960.000
16COL10A1collagen, type X, alpha 1Lung+3.790.000
17CLIC5chloride intracellular channel 5Lung-3.650.000
18ADIRFadipogenesis regulatory factorLung-3.650.000
19RAMP2receptor (G protein-coupled) activity modifying protein 2Lung-3.620.000
20HIGD1BHIG1 hypoxia inducible domain family, member 1BLung-3.600.000
21STXBP6syntaxin binding protein 6 (amisyn)Lung-3.590.000
22TMPRSS4transmembrane protease, serine 4Lung+3.530.000
23EFCC1EF-hand and coiled-coil domain containing 1Lung-3.470.000
24MFAP4microfibrillar-associated protein 4Lung-3.470.000
25ABCC3ATP-binding cassette, sub-family C (CFTR/MRP), member 3Lung+3.470.000
26TOP2Atopoisomerase (DNA) II alpha 170kDaLung+3.410.000
27TCF21transcription factor 21Lung-3.380.000
28CA4carbonic anhydrase IVLung-3.380.000
29CYP4B1cytochrome P450, family 4, subfamily B, polypeptide 1Lung-3.330.000
30GPM6Aglycoprotein M6ALung-3.300.000
31GINS2GINS complex subunit 2 (Psf2 homolog)Lung+3.290.000
32NEK2NIMA-related kinase 2Lung+3.270.000
33TOX3TOX high mobility group box family member 3Lung+3.240.000
34IL1RL1interleukin 1 receptor-like 1Lung-3.210.000
35PKNOX2PBX/knotted 1 homeobox 2Lung-3.210.000
36ABCA8ATP-binding cassette, sub-family A (ABC1), member 8Lung-3.170.000
37SCGB1A1secretoglobin, family 1A, member 1 (uteroglobin)Lung-3.170.000
38FIGFc-fos induced growth factor (vascular endothelial growth factor D)Lung-3.140.000
39CRABP2cellular retinoic acid binding protein 2Lung+3.110.000
40SGCGsarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)Lung-3.100.000
41ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif, 8Lung-3.080.000
42SFTPDsurfactant protein DLung-3.070.000
43MARCOmacrophage receptor with collagenous structureLung-3.070.000
44COL1A1collagen, type I, alpha 1Lung+3.050.000
45NMUneuromedin ULung+3.050.000
46COMPcartilage oligomeric matrix proteinLung+2.990.000
47SLC6A4solute carrier family 6 (neurotransmitter transporter), member 4Lung-2.990.000
48KANK3KN motif and ankyrin repeat domains 3Lung-2.990.000
49DPP4dipeptidyl-peptidase 4Lung+2.970.000
50HK3hexokinase 3 (white cell)Lung-2.950.000
51DPEP2dipeptidase 2Lung-2.890.000
52MMP13matrix metallopeptidase 13 (collagenase 3)Lung+2.890.000
53HBBhemoglobin, betaLung-2.880.000
54SFNstratifinLung+2.870.000
55GRK5G protein-coupled receptor kinase 5Lung-2.860.000
56CAV1caveolin 1, caveolae protein, 22kDaLung-2.860.000
57BIRC5baculoviral IAP repeat containing 5Lung+2.840.000
58KCNK3potassium channel, subfamily K, member 3Lung-2.840.000
59ADH1Balcohol dehydrogenase 1B (class I), beta polypeptideLung-2.840.000
60EEF1A2eukaryotic translation elongation factor 1 alpha 2Lung+2.830.000
61NXF3nuclear RNA export factor 3Lung-2.820.000
62KRT4keratin 4Lung-2.800.000
63MMP11matrix metallopeptidase 11 (stromelysin 3)Lung+2.790.000
64RRM2ribonucleotide reductase M2Lung+2.790.000
65EMCNendomucinLung-2.780.000
66RGCCregulator of cell cycleLung-2.770.000
67PPBPpro-platelet basic protein (chemokine (C-X-C motif) ligand 7)Lung-2.750.000
68FAM107Afamily with sequence similarity 107, member ALung-2.740.000
69LMOD1leiomodin 1 (smooth muscle)Lung-2.740.000
70LDB2LIM domain binding 2Lung-2.730.000
71CST1cystatin SNLung+2.730.000
72GPER1G protein-coupled estrogen receptor 1Lung-2.730.000
73KIF20Akinesin family member 20ALung+2.710.000
74MAOBmonoamine oxidase BLung-2.710.000
75NR4A3nuclear receptor subfamily 4, group A, member 3Lung-2.700.000
76IL33interleukin 33Lung-2.690.000
77CDC20cell division cycle 20Lung+2.680.000
78DARCDuffy blood group, atypical chemokine receptorLung-2.660.000
79FANCIFanconi anemia, complementation group ILung+2.650.000
80IGLimmunoglobulin lambda locusLung+2.650.005
81PODXL2podocalyxin-like 2Lung+2.640.000
82KAL1Kallmann syndrome 1 sequenceLung-2.630.000
83LEPRleptin receptorLung-2.620.000
84VNN2vanin 2Lung-2.620.000
85AOC3amine oxidase, copper containing 3Lung-2.620.000
86FXYD1FXYD domain containing ion transport regulator 1Lung-2.620.000
87CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5Lung+2.620.001
88CXCL13chemokine (C-X-C motif) ligand 13Lung+2.620.000
89S100A2S100 calcium binding protein A2Lung+2.610.000
90GREM1gremlin 1, DAN family BMP antagonistLung+2.610.000
91GOLM1golgi membrane protein 1Lung+2.600.000
92CFDcomplement factor D (adipsin)Lung-2.600.000
93CD36CD36 molecule (thrombospondin receptor)Lung-2.600.000
94UPK3Buroplakin 3BLung-2.590.002
95MNX1motor neuron and pancreas homeobox 1Lung+2.570.000
96PTPRBprotein tyrosine phosphatase, receptor type, BLung-2.570.000
97ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)Lung+2.570.000
98MMP12matrix metallopeptidase 12 (macrophage elastase)Lung+2.560.000
99SFTPCsurfactant protein CLung-2.560.001
100TRHDEthyrotropin-releasing hormone degrading enzymeLung-2.560.000
101CES1carboxylesterase 1Lung-2.560.000
102LRRC36leucine rich repeat containing 36Lung-2.550.000
103GPM6Bglycoprotein M6BLung-2.550.000
104HYAL1hyaluronoglucosaminidase 1Lung-2.550.000
105TMOD1tropomodulin 1Lung-2.550.000
106SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1Lung-2.550.000
107MMEmembrane metallo-endopeptidaseLung-2.540.000
108GCNT3glucosaminyl (N-acetyl) transferase 3, mucin typeLung+2.540.000
109CPceruloplasmin (ferroxidase)Lung+2.530.000
110CHRDL1chordin-like 1Lung-2.530.000
111RBP4retinol binding protein 4, plasmaLung-2.500.000
112FGFR4fibroblast growth factor receptor 4Lung-2.500.000
113WISP2WNT1 inducible signaling pathway protein 2Lung-2.500.000
114KRT15keratin 15Lung+2.500.000
115IGHMimmunoglobulin heavy constant muLung+2.500.005
116SRD5A1steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)Lung+2.490.000
117TPPP3tubulin polymerization-promoting protein family member 3Lung-2.490.000
118WFDC1WAP four-disulfide core domain 1Lung-2.480.000
119DUOX1dual oxidase 1Lung-2.480.000
120MELKmaternal embryonic leucine zipper kinaseLung+2.470.000
121NKG7natural killer cell granule protein 7Lung-2.470.000
122GNLYgranulysinLung-2.460.000
123CXorf57chromosome X open reading frame 57Lung-2.460.000
124PAFAH1B3platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)Lung+2.460.000
125GPR37G protein-coupled receptor 37 (endothelin receptor type B-like)Lung+2.450.001
126HMMRhyaluronan-mediated motility receptor (RHAMM)Lung+2.450.000
127CAV2caveolin 2Lung-2.450.000
128LGSNlengsin, lens protein with glutamine synthetase domainLung+2.450.003
129SPDEFSAM pointed domain containing ETS transcription factorLung+2.440.000
130SLIT3slit homolog 3 (Drosophila)Lung-2.440.000
131GPD1glycerol-3-phosphate dehydrogenase 1 (soluble)Lung-2.440.000
132SPTBN1spectrin, beta, non-erythrocytic 1Lung-2.430.000
133CLDN3claudin 3Lung+2.420.002
134TEKTEK tyrosine kinase, endothelialLung-2.420.000
135ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif, 1Lung-2.420.000
136KLF4Kruppel-like factor 4 (gut)Lung-2.410.000
137CDH5cadherin 5, type 2 (vascular endothelium)Lung-2.410.000
138CLDN18claudin 18Lung-2.400.000
139CENPFcentromere protein F, 350/400kDaLung+2.400.000
140VIPR1vasoactive intestinal peptide receptor 1Lung-2.380.000
141NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligaseLung-2.380.000
142C7complement component 7Lung-2.380.002
143CRLF1cytokine receptor-like factor 1Lung+2.370.006
144DPTdermatopontinLung-2.370.000
145HSPB2heat shock 27kDa protein 2Lung-2.360.000
146ALDH1A1aldehyde dehydrogenase 1 family, member A1Lung-2.360.000
147E2F8E2F transcription factor 8Lung+2.360.000
148MCM4minichromosome maintenance complex component 4Lung+2.360.000
149CSF3colony stimulating factor 3 (granulocyte)Lung-2.360.001
150MSLNmesothelinLung-2.360.021
151RECKreversion-inducing-cysteine-rich protein with kazal motifsLung-2.360.000
152LTBP4latent transforming growth factor beta binding protein 4Lung-2.340.000
153CAPN3calpain 3, (p94)Lung-2.340.004
154TNXBtenascin XBLung-2.340.000
155CHAF1Bchromatin assembly factor 1, subunit B (p60)Lung+2.340.000
156SFTPA2surfactant protein A2Lung-2.340.004
157BCHEbutyrylcholinesteraseLung-2.320.000
158ADAMTSL3ADAMTS-like 3Lung-2.320.000
159NCAPGnon-SMC condensin I complex, subunit GLung+2.320.002
160CD24CD24 moleculeLung+2.320.001
161FHL1four and a half LIM domains 1Lung-2.310.000
162MUC5Bmucin 5B, oligomeric mucus/gel-formingLung+2.310.017
163HIF3Ahypoxia inducible factor 3, alpha subunitLung-2.310.000
164EDNRBendothelin receptor type BLung-2.310.000
165MYH11myosin, heavy chain 11, smooth muscleLung-2.300.001
166DESdesminLung-2.300.000
167PECAM1platelet/endothelial cell adhesion molecule 1Lung-2.300.000
168HJURPHolliday junction recognition proteinLung+2.290.000
169CXCL14chemokine (C-X-C motif) ligand 14Lung+2.290.003
170SMAD6SMAD family member 6Lung-2.280.001
171LCATlecithin-cholesterol acyltransferaseLung-2.280.001
172AHNAKAHNAK nucleoproteinLung-2.280.000
173LYVE1lymphatic vessel endothelial hyaluronan receptor 1Lung-2.270.000
174TBX3T-box 3Lung-2.270.000
175HMGB3P1high mobility group box 3 pseudogene 1Lung+2.270.000
176LRRC32leucine rich repeat containing 32Lung-2.260.000
177TIE1tyrosine kinase with immunoglobulin-like and EGF-like domains 1Lung-2.260.000
178CDH19cadherin 19, type 2Lung-2.260.000
179MVB12Bmultivesicular body subunit 12BLung-2.260.000
180ANGPT1angiopoietin 1Lung-2.250.000
181C1orf21chromosome 1 open reading frame 21Lung-2.240.000
182CTSWcathepsin WLung-2.220.001
183COL1A2collagen, type I, alpha 2Lung+2.210.000
184CEP55centrosomal protein 55kDaLung+2.210.000
185CPB2carboxypeptidase B2 (plasma)Lung-2.210.003
186LPLlipoprotein lipaseLung-2.200.000
187SNX1sorting nexin 1Lung-2.190.000
188PCDH7protocadherin 7Lung+2.190.002
189HSD17B6hydroxysteroid (17-beta) dehydrogenase 6Lung-2.190.001
190EMP2epithelial membrane protein 2Lung-2.190.000
191CENPEcentromere protein E, 312kDaLung+2.190.000
192ARHGAP6Rho GTPase activating protein 6Lung-2.180.000
193HBEGFheparin-binding EGF-like growth factorLung-2.180.000
194PDZD2PDZ domain containing 2Lung-2.170.000
195ZBTB16zinc finger and BTB domain containing 16Lung-2.170.000
196EFNA3ephrin-A3Lung+2.160.000
197RAMP3receptor (G protein-coupled) activity modifying protein 3Lung-2.160.000
198TGFBR3transforming growth factor, beta receptor IIILung-2.160.000
199PGCprogastricsin (pepsinogen C)Lung-2.160.000
200SOCS2suppressor of cytokine signaling 2Lung-2.160.000
201EPN3epsin 3Lung+2.150.001
202LEPREL4leprecan-like 4Lung+2.150.000
203MYRFmyelin regulatory factorLung-2.150.000
204EPAS1endothelial PAS domain protein 1Lung-2.150.000
205BIKBCL2-interacting killer (apoptosis-inducing)Lung+2.150.001
206COL3A1collagen, type III, alpha 1Lung+2.150.000
207B3GNT3UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3Lung+2.150.000
208GDF10growth differentiation factor 10Lung-2.140.000
209NUDT1nudix (nucleoside diphosphate linked moiety X)-type motif 1Lung+2.140.001
210GRIA1glutamate receptor, ionotropic, AMPA 1Lung-2.130.000
211THBDthrombomodulinLung-2.130.000
212ACADLacyl-CoA dehydrogenase, long chainLung-2.130.000
213FGFR2fibroblast growth factor receptor 2Lung-2.120.004
214LYPD1LY6/PLAUR domain containing 1Lung+2.120.001
215FOXM1forkhead box M1Lung+2.120.000
216GPC3glypican 3Lung-2.110.000
217WFDC2WAP four-disulfide core domain 2Lung+2.110.000
218SEMA3Esema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3ELung-2.110.005
219ADARB1adenosine deaminase, RNA-specific, B1Lung-2.110.000
220AK4adenylate kinase 4Lung+2.110.002
221CACNA2D2calcium channel, voltage-dependent, alpha 2/delta subunit 2Lung-2.110.000
222IL6interleukin 6 (interferon, beta 2)Lung-2.100.003
223PTGDSprostaglandin D2 synthase 21kDa (brain)Lung-2.100.000
224DAPK2death-associated protein kinase 2Lung-2.100.000
225NPR1natriuretic peptide receptor 1Lung-2.100.000
226TTKTTK protein kinaseLung+2.090.000
227GZMHgranzyme H (cathepsin G-like 2, protein h-CCPX)Lung-2.090.001
228FOXF1forkhead box F1Lung-2.090.000
229PTPRN2protein tyrosine phosphatase, receptor type, N polypeptide 2Lung-2.080.001
230LAMP3lysosomal-associated membrane protein 3Lung-2.080.000
231FBLN5fibulin 5Lung-2.080.000
232SMPDL3Bsphingomyelin phosphodiesterase, acid-like 3BLung+2.080.008
233SPOCK2sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2Lung-2.080.000
234NDC80NDC80 kinetochore complex componentLung+2.080.001
235MKI67marker of proliferation Ki-67Lung+2.080.000
236ADAM28ADAM metallopeptidase domain 28Lung+2.080.004
237GIMAP6GTPase, IMAP family member 6Lung-2.070.000
238CLDN5claudin 5Lung-2.070.001
239PCP4Purkinje cell protein 4Lung+2.070.016
240HPGDhydroxyprostaglandin dehydrogenase 15-(NAD)Lung-2.070.000
241SORBS1sorbin and SH3 domain containing 1Lung-2.060.001
242CCNE1cyclin E1Lung+2.060.000
243KCNAB1potassium voltage-gated channel, shaker-related subfamily, beta member 1Lung-2.060.001
244SEMA3Gsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3GLung-2.060.000
245BIN2bridging integrator 2Lung-2.060.000
246PLA1Aphospholipase A1 member ALung-2.060.001
247FMO2flavin containing monooxygenase 2 (non-functional)Lung-2.060.000
248C11orf80chromosome 11 open reading frame 80Lung+2.050.004
249IGLV3-19immunoglobulin lambda variable 3-19Lung+2.050.008
250CDCA3cell division cycle associated 3Lung+2.050.000
251PLEK2pleckstrin 2Lung+2.040.001
252KCNK1potassium channel, subfamily K, member 1Lung+2.040.002
253QPRTquinolinate phosphoribosyltransferaseLung+2.040.013
254ENC1ectodermal-neural cortex 1 (with BTB domain)Lung+2.030.012
255ETV4ets variant 4Lung+2.010.001
256ADAM12ADAM metallopeptidase domain 12Lung+2.010.003
257HMGB3high mobility group box 3Lung+2.010.000
258HOXA10homeobox A10Lung+2.010.009
259TPX2TPX2, microtubule-associatedLung+2.000.000
260PYCR1pyrroline-5-carboxylate reductase 1Lung+2.000.000
261SOX4SRY (sex determining region Y)-box 4Lung+2.000.003
262TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)Lung+1.990.000
263TFPI2tissue factor pathway inhibitor 2Lung+1.980.047
264PPAP2Cphosphatidic acid phosphatase type 2CLung+1.980.000
265SULF1sulfatase 1Lung+1.980.000
266PHLDA2pleckstrin homology-like domain, family A, member 2Lung+1.960.001
267FRKfyn-related kinaseLung+1.960.011
268GPR87G protein-coupled receptor 87Lung+1.950.020
269CCNB1cyclin B1Lung+1.950.000
270ABCA4ATP-binding cassette, sub-family A (ABC1), member 4Lung+1.940.003
271KIAA0101KIAA0101Lung+1.940.000
272HIST1H2BGhistone cluster 1, H2bgLung+1.940.009
273EFNA4ephrin-A4Lung+1.930.001
274SQSTM1sequestosome 1Lung+1.910.004
275MUC16mucin 16, cell surface associatedLung+1.900.030
276KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4Lung+1.900.002
277KIF4Akinesin family member 4ALung+1.870.001
278MYBL2v-myb avian myeloblastosis viral oncogene homolog-like 2Lung+1.870.016
279THBS2thrombospondin 2Lung+1.870.000
280ERO1LERO1-like (S. cerevisiae)Lung+1.870.001
281ITPKAinositol-trisphosphate 3-kinase ALung+1.850.030
282PHKA1phosphorylase kinase, alpha 1 (muscle)Lung+1.850.000
283PEX6peroxisomal biogenesis factor 6Lung+1.840.010
284NPTX2neuronal pentraxin IILung+1.840.023
285GINS1GINS complex subunit 1 (Psf1 homolog)Lung+1.830.001
286DLGAP5discs, large (Drosophila) homolog-associated protein 5Lung+1.830.001
287WHSC1Wolf-Hirschhorn syndrome candidate 1Lung+1.820.007
288EZH2enhancer of zeste homolog 2 (Drosophila)Lung+1.820.003
289LRRC31leucine rich repeat containing 31Lung+1.810.037
290AGR2anterior gradient 2Lung+1.810.001
291LSM12LSM12 homolog (S. cerevisiae)Lung+1.800.007
292AURKAaurora kinase ALung+1.800.000
293GALNT14polypeptide N-acetylgalactosaminyltransferase 14Lung+1.780.015
294TK1thymidine kinase 1, solubleLung+1.780.001
295GDF15growth differentiation factor 15Lung+1.780.007
296SPAG4sperm associated antigen 4Lung+1.770.013
297PCSK1Nproprotein convertase subtilisin/kexin type 1 inhibitorLung+1.760.003
298CENPNcentromere protein NLung+1.760.040
299PYCRLpyrroline-5-carboxylate reductase-likeLung+1.760.008
300HUS1HUS1 checkpoint homolog (S. pombe)Lung+1.750.009
301DEPTORDEP domain containing MTOR-interacting proteinLung+1.750.000
302AURKBaurora kinase BLung+1.750.006
303COL5A1collagen, type V, alpha 1Lung+1.750.003
304MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)Lung+1.740.001
305COL17A1collagen, type XVII, alpha 1Lung+1.740.035
306SCG5secretogranin V (7B2 protein)Lung+1.740.006
307CTTNcortactinLung+1.740.009
308LCN2lipocalin 2Lung+1.740.030
309NQO1NAD(P)H dehydrogenase, quinone 1Lung+1.730.049
310CDK1cyclin-dependent kinase 1Lung+1.720.001
311FERMT1fermitin family member 1Lung+1.720.011
312CCNB2cyclin B2Lung+1.720.002
313MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)Lung+1.720.005
314CDT1chromatin licensing and DNA replication factor 1Lung+1.710.013
315SPAG5sperm associated antigen 5Lung+1.710.009
316TMEM156transmembrane protein 156Lung+1.700.048
317PTK6protein tyrosine kinase 6Lung+1.700.036
318ADAMDEC1ADAM-like, decysin 1Lung+1.700.027
319PBKPDZ binding kinaseLung+1.690.008
320SLC2A1solute carrier family 2 (facilitated glucose transporter), member 1Lung+1.670.000
321GRIK2glutamate receptor, ionotropic, kainate 2Lung+1.670.039
322PTTG3Ppituitary tumor-transforming 3, pseudogeneLung+1.670.042
323KDELR2KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2Lung+1.670.001
324GGCTgamma-glutamylcyclotransferaseLung+1.670.000
325UBE2Cubiquitin-conjugating enzyme E2CLung+1.670.001
326PLXNB3plexin B3Lung+1.660.006
327HIST1H4Jhistone cluster 1, H4jLung+1.660.040
328MDKmidkine (neurite growth-promoting factor 2)Lung+1.660.028
329PAICSphosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetaseLung+1.660.004
330PNPLA4patatin-like phospholipase domain containing 4Lung+1.650.019
331RHODras homolog family member DLung+1.650.047
332TYMSthymidylate synthetaseLung+1.650.001
333IGLJ3immunoglobulin lambda joining 3Lung+1.640.044
334KIF2Ckinesin family member 2CLung+1.640.001
335SERPINH1serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)Lung+1.640.021
336FLJ22184putative uncharacterized protein FLJ22184Lung+1.640.012
337KIF11kinesin family member 11Lung+1.640.019
338MMP10matrix metallopeptidase 10 (stromelysin 2)Lung+1.630.048
339BZW2basic leucine zipper and W2 domains 2Lung+1.630.000
340SMYD5SMYD family member 5Lung+1.630.023
341IGKV1D-8immunoglobulin kappa variable 1D-8Lung+1.630.039
342CDKN3cyclin-dependent kinase inhibitor 3Lung+1.630.004

Expression patterns in normal tissues for genes affiliated with Lung Adenocarcinoma

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Pathways for genes affiliated with Lung Adenocarcinoma

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Pathways related to Lung Adenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7KRAS, MIR200A, MIR100

Compounds for genes affiliated with Lung Adenocarcinoma

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GO Terms for genes affiliated with Lung Adenocarcinoma

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Products for genes affiliated with Lung Adenocarcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Lung Adenocarcinoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet