MCID: LNG054
MIFTS: 23

Lung Agenesis malady

Categories: Rare diseases, Respiratory diseases, Fetal diseases

Aliases & Classifications for Lung Agenesis

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Sources:
45NIH Rare Diseases, 51Orphanet, 65UMLS, 28ICD10 via Orphanet, 66UMLS via Orphanet, 27ICD10
See all MalaCards sources

Aliases & Descriptions for Lung Agenesis:

Name: Lung Agenesis 45
Pulmonary Agenesis 45 51
Unilateral Lobar Pulmonary Agenesis 45
 
Congenital Absence of Lung 65
Congenital Lung Agenesis 45
Unilateral Lung Agenesis 45

Classifications:



External Ids:

Orphanet51 984
ICD10 via Orphanet28 Q33.3
UMLS via Orphanet66 C0265780
ICD1027 Q33.3
UMLS65 C0265780

Summaries for Lung Agenesis

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MalaCards based summary: Lung Agenesis, also known as pulmonary agenesis, is related to microphthalmia, syndromic 9 and manouvrier syndrome. An important gene associated with Lung Agenesis is TBX5 (T-Box 5). Affiliated tissues include lung, bone and breast.

Related Diseases for Lung Agenesis

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Graphical network of the top 20 diseases related to Lung Agenesis:



Diseases related to lung agenesis

Symptoms for Lung Agenesis

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Drugs & Therapeutics for Lung Agenesis

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Drugs for Lung Agenesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1MitogensPhase 1, Phase 21386

Interventional clinical trials:

idNameStatusNCT IDPhase
1Safety Study of Autologous Bone Marrow Stromal Cells With Modification by Hepatocyte Growth Factor to Treat SilicosisCompletedNCT01977131Phase 1, Phase 2
2Safety of Stem Cells Intrabronchial Instillation for SilicosisCompletedNCT01239862Phase 1
3Safety Study of Bone-marrow Derived Mesenchymal Stromal Cells Associated With Endobronchial Valves in EmphysemaCompletedNCT01872624
4Lung Inflammation and Lung Metastases From Breast CancerActive, not recruitingNCT01182519
5Validation of a Multi-gene Test for Lung Cancer RiskActive, not recruitingNCT01130285

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Genetic Tests for Lung Agenesis

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Anatomical Context for Lung Agenesis

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MalaCards organs/tissues related to Lung Agenesis:

33
Lung, Bone, Breast, Testes, Bone marrow, T cells, B cells

Animal Models for Lung Agenesis or affiliated genes

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Publications for Lung Agenesis

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Articles related to Lung Agenesis:

(show all 41)
idTitleAuthorsYear
1
Depletion of pre-mRNA splicing factor Cdc5L inhibits mitotic progression and triggers mitotic catastrophe. (24675469)
2014
2
Mesenteric desmoid-type fibromatosis causing secondary hypertension in a young woman. (25264535)
2014
3
A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis. (23337983)
2013
4
Bedside lung ultrasound: a case of neurogenic pulmonary edema. (23479070)
2013
5
The vascular permeabilizing factors histamine and serotonin induce angiogenesis through TR3/Nur77 and subsequently truncate it through thrombospondin-1. (23315169)
2013
6
Phylogenetic and pathogenic analyses of avian influenza A H5N1 viruses isolated from poultry in Vietnam. (23226433)
2012
7
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. (22897851)
2012
8
Free tissue transfer in reconstruction following soft tissue sarcoma resection. (21630335)
2011
9
Association analysis of the SOX10 polymorphism with Hirschsprung disease in the Han Chinese population. (22008330)
2011
10
NFAT promotes carcinoma invasive migration through glypican-6. (21871017)
2011
11
Mechanical force augments the anti-osteoclastogenic potential of human gingival fibroblasts in vitro. (18842115)
2009
12
Interaction of Sindbis virus non-structural protein 3 with poly(ADP-ribose) polymerase 1 in neuronal cells. (19515826)
2009
13
Mechanism of eosinophilic esophagitis. (19141339)
2009
14
Effect of latanoprost and timolol on the histopathology of the human conjunctiva. (18971237)
2009
15
A quantitative analysis of N-myc downstream regulated gene 2 (NDRG 2) in human tissues and cell lysates by reverse-phase protein microarray. (17936257)
2008
16
Anti-TNF-alpha therapies in chronic obstructive pulmonary diseases. (18616416)
2008
17
Expression of cyclin D1 and p27kip1 in renal cell carcinoma and its significance]. (17924468)
2007
18
Comprehensive review of conventional and non-conventional methods of management of recurrent vulvovaginal candidiasis. (17627679)
2007
19
Essential roles of PI-3K/Akt/IKKbeta/NFkappaB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells. (16387740)
2006
20
Toxic death-case after capecitabine + oxaliplatin (XELOX) administration: probable implication of dihydropyrimidine deshydrogenase deficiency. (16292536)
2006
21
Magnetic resonance imaging of syringocystadenoma papilliferum of the external auditory canal. (16168591)
2006
22
Severe obstructive sleep apnea/hypopnea mimicking REM sleep behavior disorder. (16171244)
2005
23
Oral manifestations of juvenile hyaline fibromatosis: a case report. (16161402)
2005
24
Association of interleukin-8 and plasminogen activator system in the progression of colorectal cancer. (16088182)
2005
25
Detection of hypermethylated genes in women with and without cervical neoplasia. (15713962)
2005
26
Identification and characterization of a gene encoding human LPGAT1, an endoplasmic reticulum-associated lysophosphatidylglycerol acyltransferase. (15485873)
2004
27
Up-regulation, nuclear import, and tumor growth stimulation of the adhesion protein p120 in pancreatic cancer. (12671892)
2003
28
The Arabidopsis SYN1 cohesin protein is required for sister chromatid arm cohesion and homologous chromosome pairing. (12783989)
2003
29
A seroepidemiological survey for toxocariasis in apparently healthy residents in Gangwon-do, Korea. (12325440)
2002
30
Pelizaeus-Merzbacher disease. (12230321)
2002
31
Phosphorylation of mitogen-activated protein kinase is inhibited by calcitonin in DU145 prostate cancer cells. (11507054)
2001
32
Clinicopathological and molecular evidence indicating the independence of bronchioloalveolar components from other subtypes of human peripheral lung adenocarcinoma. (11410513)
2001
33
Molecular detection of c-mpl thrombopoietin receptor gene expression in chronic myeloproliferative disorders. (10621836)
1999
34
Expression of types I, II, and III TGF-beta receptors in human glomerulonephritis. (9848779)
1998
35
Glycosylated extracellular domains of membrane immunoglobulin M contribute to its association with mb-1/B29 gene products and the B cell receptor complex. (9561918)
1998
36
High and constant plasma levels of tissue plasminogen activator and PEG-hirudin can be achieved by subcutaneous delivery. (9253807)
1997
37
Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine "mini-cluster". (8976378)
1996
38
Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors. (8662841)
1996
39
Comparative distribution of receptors for amylin and the related peptides calcitonin gene related peptide and calcitonin in rat and monkey brain. (8846397)
1995
40
Effects of blood transfusion on the serum assays of iron, the total binding capacity of transferrin, vitamin B12 and folates]. (8009060)
1993
41
Recurrent pyogenic granuloma with multiple satellites. Clinicopathological and ultrastructural study. (6852324)
1983

Variations for Lung Agenesis

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Expression for genes affiliated with Lung Agenesis

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Search GEO for disease gene expression data for Lung Agenesis.

Pathways for genes affiliated with Lung Agenesis

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GO Terms for genes affiliated with Lung Agenesis

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Sources for Lung Agenesis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet