MCID: LNG054
MIFTS: 23

Lung Agenesis malady

Rare diseases, Respiratory diseases, Fetal diseases categories

Aliases & Classifications for Lung Agenesis

About this section
Sources:
45NIH Rare Diseases, 51Orphanet, 28ICD10 via Orphanet, 66UMLS via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Lung Agenesis:

Name: Lung Agenesis 45
Pulmonary Agenesis 45 51
Unilateral Lobar Pulmonary Agenesis 45
 
Unilateral Lung Agenesis 45
Congenital Lung Agenesis 45


Classifications:



External Ids:

Orphanet51 984
ICD10 via Orphanet28 Q33.3
UMLS via Orphanet66 C0265780
ICD1027 Q33.3

Summaries for Lung Agenesis

About this section
MalaCards based summary: Lung Agenesis, also known as pulmonary agenesis, is related to esophageal atresia and esophagitis. An important gene associated with Lung Agenesis is TBX5 (T-Box 5). Affiliated tissues include lung, heart and bone.

Related Diseases for Lung Agenesis

About this section

Diseases related to Lung Agenesis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
idRelated DiseaseScoreTop Affiliating Genes
1esophageal atresia10.2
2esophagitis10.2
3microphthalmia10.1
4microtia10.1
5dextrocardia10.1
6tracheal stenosis10.1
7ventricular septal defect10.1
8manouvrier syndrome10.1
9hydrolethalus syndrome10.0
10down syndrome10.0
11dysostosis10.0
12pneumothorax10.0
13congenital tracheal stenosis10.0
14asthma9.9
15allergic rhinitis9.9
16holt-oram syndrome9.9
17microphthalmia, syndromic 99.9
18serkal syndrome9.9
19patent ductus arteriosus9.9
20duodenitis9.9
21mediastinitis9.9
22rhinitis9.9
23duodenal atresia9.9
24tracheoesophageal fistula9.9
25tricuspid atresia9.9

Graphical network of the top 20 diseases related to Lung Agenesis:



Diseases related to lung agenesis

Symptoms for Lung Agenesis

About this section

Drugs & Therapeutics for Lung Agenesis

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1Safety Study of Autologous Bone Marrow Stromal Cells With Modification by Hepatocyte Growth Factor to Treat SilicosisCompletedNCT01977131Phase 1, Phase 2
2Safety of Stem Cells Intrabronchial Instillation for SilicosisCompletedNCT01239862Phase 1
3Safety Study of Bone-marrow Derived Mesenchymal Stromal Cells Associated With Endobronchial Valves in EmphysemaCompletedNCT01872624
4Lung Inflammation and Lung Metastases From Breast CancerActive, not recruitingNCT01182519
5Validation of a Multi-gene Test for Lung Cancer RiskActive, not recruitingNCT01130285

Search NIH Clinical Center for Lung Agenesis

Genetic Tests for Lung Agenesis

About this section

Anatomical Context for Lung Agenesis

About this section

MalaCards organs/tissues related to Lung Agenesis:

33
Lung, Heart, Bone, Bone marrow

Animal Models for Lung Agenesis or affiliated genes

About this section

Publications for Lung Agenesis

About this section

Articles related to Lung Agenesis:

(show all 40)
idTitleAuthorsYear
1
Transcatheter Amplatzer Duct Occluder II closure of perimembranous ventricular septal defect with right lung agenesis. (25135329)
2014
2
Persistent Cloaca associated with Unilateral Lung Agenesis- A Rare Presentation. (26023493)
2014
3
Neonatal repair of total anomalous pulmonary venous connection and lung agenesis. (24585319)
2014
4
Prenatal diagnosis of fetal unilateral lung agenesis complicated with cardiac malposition. (23530545)
2013
5
First description of unilateral lung agenesis and anomalous pulmonary venous connection in a newborn with Goldenhar syndrome. (22309948)
2012
6
Complete right lung agenesis presenting with bronchial asthma and allergic rhinitis. (23001088)
2012
7
Complete right lung agenesis with dextrocardia: an unusual cause of respiratory distress. (23393637)
2012
8
Left lung agenesis associated with common origin of both coronary arteries. (23284132)
2012
9
Right lung agenesis and dextrocardia in a paucisymptomatic 11-year-old child. (22088223)
2012
10
Aphallia, lung agenesis and multiple defects of blastogenesis. (21204662)
2011
11
Balloon dilatation of tracheal restenosis in a patient with unilateral lung agenesis - an anesthetic challenge. (21793985)
2011
12
Repair of a ventricular septal defect in a patient with left lung agenesis. (21810119)
2011
13
Cardiac defect with diaphragmatic hernia and left lung agenesis--heart disease and other anomalies. (20922633)
2010
14
Unilateral left lung agenesis with crossed-ectopic right lower lobe combined tricuspid atresia diagnosed by ECG gated computed tomography. (19660389)
2010
15
Postpneumonectomy-like syndrome in an infant with right lung agenesis and left main bronchus hypoplasia. (19379854)
2009
16
Tracheal reconstruction in children with unilateral lung agenesis or severe hypoplasia. (19632424)
2009
17
Unilateral lung agenesis: coincidence or association with maternal valproate therapy? (19825029)
2009
18
Mardini-Nyhan association (lung agenesis, congenital heart, and thumb anomalies): three new cases and possible recurrence in a sib-is there a distinct recessive syndrome? (19938090)
2009
19
Right lung agenesis. (19858680)
2008
20
Adult presentation of right lung agenesis and left pulmonary artery sling. (17963072)
2008
21
MDCT and 3D evaluation of type 2 hypoplastic pulmonary artery sling associated with right lung agenesis, hypoplastic aortic arch, and long segment tracheal stenosis. (18043391)
2007
22
Holt-Oram syndrome with right lung agenesis caused by a de novo mutation in the TBX5 gene. (17366586)
2007
23
Left atrial approach to close the atrial septal defect type II in case of right lung agenesis with extreme dextroversion. (17669789)
2007
24
Unilateral lung agenesis--detrimental roles of surrounding vessels. (17238192)
2007
25
Pregnancy in a woman with unilateral lung agenesis. (15280115)
2004
26
Esophageal atresia, duodenal atresia, and unilateral lung agenesis: a case report. (15300548)
2004
27
Mitral valve repair in a 55-year-old man with left lung agenesis. (15111192)
2004
28
Esophageal atresia associated with tracheal stenosis and right lung agenesis: report of one case. (12632790)
2002
29
Subclavian and pulmonary steal phenomenon in isolated left subclavian artery with left lung agenesis. (12227719)
2002
30
Lung agenesis in a neonate presenting with contralateral mediastinal shift. (11733859)
2001
31
Combined spinal epidural anesthesia for cesarean section in a patient with left lung agenesis. (15321627)
2001
32
Right lung agenesis with left pulmonary artery sling. (10686046)
2000
33
Pregnancy with unilateral lung agenesis. (11304979)
2000
34
The association of complete laryngotracheoesophageal cleft with left lung agenesis: pathophysiological clues provided by an experiment of nature. (9802811)
1998
35
Prenatal diagnosis of right lung agenesis using color Doppler and magnetic resonance imaging. (9475368)
1997
36
Right lung agenesis with total anomalous pulmonary venous drainage. (7875708)
1994
37
Lung agenesis, esophageal atresia and tracheoesophageal fistula. (3385599)
1988
38
Right lung agenesis. A case report. (7152188)
1982
39
Tracheal compression by a normal aorta associated with right lung agenesis. (424535)
1979
40
Pseudovascular ring resulting from right lung agenesis, normal aortic arch, and patent ductus arteriosus. Case report. (5953538)
1966

Variations for Lung Agenesis

About this section

Expression for genes affiliated with Lung Agenesis

About this section
Search GEO for disease gene expression data for Lung Agenesis.

Pathways for genes affiliated with Lung Agenesis

About this section

GO Terms for genes affiliated with Lung Agenesis

About this section

Sources for Lung Agenesis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet