Aliases & Classifications for Lung Disease

MalaCards integrated aliases for Lung Disease:

Name: Lung Disease 12 14
Lung Diseases 52 41 42 69
Disorder of Lung 29

Classifications:



External Ids:

Disease Ontology 12 DOID:850
ICD10 33 J98.4 J60-J70
MeSH 42 D008171
NCIt 47 C3198
UMLS 69 C0024115

Summaries for Lung Disease

MedlinePlus : 41 when you breathe, your lungs take in oxygen from the air and deliver it to the bloodstream. the cells in your body need oxygen to work and grow. during a normal day, you breathe nearly 25,000 times. people with lung disease have difficulty breathing. millions of people in the u.s. have lung disease. if all types of lung disease are lumped together, it is the number three killer in the united states. the term lung disease refers to many disorders affecting the lungs, such as asthma, copd, infections like influenza, pneumonia and tuberculosis, lung cancer, and many other breathing problems. some lung diseases can lead to respiratory failure. dept. of health and human services office on women's health

MalaCards based summary : Lung Disease, also known as lung diseases, is related to pulmonary hypertension and pulmonary sarcoidosis, and has symptoms including coughing, dyspnea and hemoptysis. An important gene associated with Lung Disease is SFTPC (Surfactant Protein C), and among its related pathways/superpathways are Metabolism of proteins and Toll-like Receptor Signaling Pathway. The drugs Beractant and Budesonide have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and heart, and related phenotypes are homeostasis/metabolism and mortality/aging

Disease Ontology : 12 A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.

Related Diseases for Lung Disease

Diseases related to Lung Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 433)
id Related Disease Score Top Affiliating Genes
1 pulmonary hypertension 32.4 IL1B TNF
2 pulmonary sarcoidosis 31.6 ELANE SERPINA1 SFTPD
3 asbestosis 31.5 CXCL8 IL1B MUC5B TNF
4 middle lobe syndrome 31.4 CXCL8 ELANE MUC5B SFTPA1 SFTPA2 SFTPC
5 acute chest syndrome 30.8 CFTR CXCL8 ELANE IL1B MUC5B SERPINA1
6 mycobacterium kansasii 30.7 CFTR CXCL8 SERPINA1 TNF
7 burns 30.3 CXCL8 ELANE SFTPB
8 interstitial lung disease 12.3
9 rheumatoid lung disease 12.1
10 nontuberculous mycobacterial lung disease 12.1
11 children's interstitial lung disease 12.0
12 interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa, congenital 12.0
13 lung disease, immunodeficiency, and chromosome breakage syndrome 11.9
14 drug or radiation exposure-related interstitial lung disease 11.8
15 respiratory bronchiolitis-interstitial lung disease syndrome 11.8
16 anthracosis 11.4
17 chronic beryllium disease 11.4
18 surfactant metabolism dysfunction, pulmonary, 2 11.4
19 farmer's lung 11.3
20 autoimmune interstitial lung, joint, and kidney disease 11.2
21 pneumoconiosis 11.2
22 extrinsic allergic alveolitis 11.2
23 byssinosis 11.1
24 pulmonary disease, chronic obstructive 11.1
25 interstitial pneumonitis, desquamative, familial 11.1
26 rrm2b-related mitochondrial disease 11.1 SFTPC TERT
27 berylliosis 11.1
28 cystic fibrosis 11.1
29 tracheoesophageal fistula symphalangism 11.1 SFTPB SFTPD
30 silicosis 11.0
31 malignant neoplasm of acoustic nerve 11.0 SFTPA1 SFTPA2 SFTPD
32 coronary stenosis 11.0 SFTPB SFTPC SFTPD
33 bagassosis 11.0
34 aspergillosis 11.0
35 neurotrophic keratoconjunctivitis 11.0 SFTPB SFTPC SFTPD
36 hypersensitivity pneumonitis, familial 11.0
37 dermatomyositis 11.0
38 surfactant dysfunction 11.0
39 antisynthetase syndrome 11.0
40 pulmonary fibrosis 11.0
41 dissociated nystagmus 11.0 CFTR SFTPA2 SFTPD
42 common variable immunodeficiency 11.0
43 pasteurellosis 11.0 CXCL8 SFTPB TNF
44 buschke-ollendorff syndrome 11.0 TSC1 TSC2
45 respiratory failure 10.9
46 trachea sarcoma 10.9 CXCL8 TERT TNF
47 bronchopulmonary dysplasia 10.9
48 lymphangioleiomyomatosis 10.9
49 tricuspid valve prolapse 10.9 ABCA3 SERPINA1 SFTPC
50 dehydration polycythemia 10.9 CXCL8 MUC5B TNF

Graphical network of the top 20 diseases related to Lung Disease:



Diseases related to Lung Disease

Symptoms & Phenotypes for Lung Disease

UMLS symptoms related to Lung Disease:


coughing, dyspnea, hemoptysis, snoring, labored breathing

MGI Mouse Phenotypes related to Lung Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.17 MUC5B SFTPA1 SFTPB SFTPD TERT TNF
2 mortality/aging MP:0010768 10.03 ABCA3 CFTR ELANE IFIH1 IL1B ITGA3
3 immune system MP:0005387 10 SFTPD TERT TNF CFTR ELANE IFIH1
4 neoplasm MP:0002006 9.56 ELANE IL1B ITGA3 SFTPC TERT TNF
5 respiratory system MP:0005388 9.36 ABCA3 CFTR ITGA3 MUC5B SFTPA1 SFTPB

Drugs & Therapeutics for Lung Disease

Drugs for Lung Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1302)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Beractant Approved Phase 4,Phase 2 108778-82-1
2
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51333-22-3 63006 5281004
3
Bosentan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 147536-97-8 104865
4
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1 83905-01-5 55185 53477736 447043
5
Caspofungin Approved Phase 4,Phase 1,Phase 2 179463-17-3, 162808-62-0 468682 2826718
6
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
7
Iloprost Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 78919-13-8 6443959
8
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
9
Metoprolol Approved, Investigational Phase 4,Phase 3 37350-58-6, 51384-51-1 4171
10
Terbutaline Approved Phase 4,Phase 3,Phase 2,Phase 1 23031-25-6 5403
11
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10102-43-9 145068
12
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 564-25-0 54671203
13
Simvastatin Approved Phase 4,Phase 3,Phase 2,Phase 1 79902-63-9 54454
14
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 69-65-8 453 6251
15
Ipratropium Approved Phase 4,Phase 3,Phase 2,Phase 1 22254-24-6, 60205-81-4 43232
16
Procaterol Approved Phase 4,Phase 3,Phase 2,Phase 1 72332-33-3 688561
17
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
18 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1
19
Isoniazid Approved Phase 4,Phase 3,Phase 2 54-85-3 3767
20
Pyrazinamide Approved Phase 4,Phase 3,Phase 2 98-96-4 1046
21
Rifampin Approved Phase 4,Phase 3,Phase 2,Phase 1 13292-46-1 5458213 5381226
22
Epoprostenol Approved Phase 4,Phase 3,Phase 2 61849-14-7, 35121-78-9 5280427 5282411
23
Tadalafil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 171596-29-5 110635
24
Metformin Approved Phase 4,Phase 2 657-24-9 14219 4091
25
Benzocaine Approved Phase 4,Phase 2,Phase 3,Phase 1 1994-09-7, 94-09-7 2337
26
Dalteparin Approved Phase 4,Phase 3,Phase 2,Early Phase 1 9005-49-6
27
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6 772 46507594
28
Riluzole Approved, Investigational Phase 4 1744-22-5 5070
29
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
30
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 1 59467-70-8 4192
31
Remifentanil Approved Phase 4 132875-61-7 60815
32
Cefuroxime Approved Phase 4,Phase 2,Phase 3 55268-75-2 5361202 5479529
33
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 85721-33-1 2764
34
Clarithromycin Approved Phase 4,Phase 3,Phase 2,Early Phase 1 81103-11-9 84029
35
Moxifloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 354812-41-2, 151096-09-2 152946
36
Penicillin G Approved, Vet_approved Phase 4,Phase 3 61-33-6 5904
37
Piperacillin Approved Phase 4,Phase 2,Phase 3 66258-76-2 43672
38
Tazobactam Approved Phase 4,Phase 2,Phase 3,Phase 1 89786-04-9 123630
39
Daclizumab Approved, Investigational Phase 4,Phase 2 152923-56-3
40
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
41
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
42
Calcium Carbonate Approved Phase 4,Phase 1 471-34-1
43
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
44
Linezolid Approved, Investigational Phase 4,Phase 3,Phase 2 165800-03-3 441401
45
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 83-43-2 6741
46
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-24-8 5755
47
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757
48
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1 57-63-6 5991
49
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 100986-85-4 149096
50
Metronidazole Approved Phase 4,Phase 3,Phase 1,Phase 2 443-48-1 4173

Interventional clinical trials:

(show top 50) (show all 10000)

id Name Status NCT ID Phase Drugs
1 Prevention of Chronic Lung Disease (CLD) in Preterm Infants Unknown status NCT00883532 Phase 4 budesonide;surfactant and air (placebo)
2 Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or Hypoxia Unknown status NCT01449253 Phase 4 Sildenafil;Bosentan
3 Prophylactic Antibiotic Treatment of Patients With Chronic Obstructive Lung Disease (COLD) Unknown status NCT00132860 Phase 4 azithromycin
4 Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study Unknown status NCT00637065 Phase 4 Bosentan;Placebo
5 Ambulatory Oxygen in Fibrotic Lung Disease (FLD) (AmbOx) Unknown status NCT02286063 Phase 4 Ambulatory Oxygen
6 Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT01721291 Phase 4 SALBUTAMOL
7 Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease Unknown status NCT01499433 Phase 4 caspofungin
8 Seasonal Influenza Vaccine, Quadrivalent Versus Trivalent in Patients With Advanced Chronic Obstructive Pulmonary Disease Unknown status NCT02563184 Phase 4
9 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease Unknown status NCT01595750 Phase 4 Roflumilast 500;Placebo
10 Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype Unknown status NCT01431625 Phase 4
11 Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients Unknown status NCT01131806 Phase 4 fluticasone/ salmeterol 125/25 mcg/puff;fluticasone/ salmeterol 250/25 mcg/puff
12 Inhaled Iloprost for Disproportionate Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT01116063 Phase 4 Inhaled iloprost
13 The Role of Opinion Leaders in Enhancing Evidence-based Care After Chronic Obstructive Pulmonary Disease (COPD) Emergency Department (ED) Visits Unknown status NCT01107613 Phase 4
14 Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00288548 Phase 4 Metoprolol
15 Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease Unknown status NCT01465906 Phase 4 tulobuterol;Tiotropium Bromide;tiotropium bromide
16 Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial Unknown status NCT00120978 Phase 4 Advair;Flovent
17 Exacerbation Prevention GOLD IV COPD With Non Invasive Mechanical Ventilation Unknown status NCT01481727 Phase 4
18 Small Airways Evaluation and Treatment Unknown status NCT02526758 Phase 4 beclomethasone;formoterol;budesonide
19 Exhaled NO Based Treatment of Chronic Obstructive Pulmonary Disease (COPD), ICS/LABA Versus LAMA Unknown status NCT02546349 Phase 4 fluticasone/salmeterol, tiotropium
20 Pulmonary Gas Exchange Response to Indacaterol in COPD Unknown status NCT02547558 Phase 4 Indacaterol
21 Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00857038 Phase 4 Doxycycline;Placebo
22 Simvastatin in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00680641 Phase 4 Simvastatin;Placebo
23 Predictor for an Additional Benefit of Inhaled Corticosteroid in Patients Treated With Tiotropium for COPD Unknown status NCT00860938 Phase 4 Budesonide
24 Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary Tuberculosis Unknown status NCT00216333 Phase 4 combined fixed dose combination
25 Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients Unknown status NCT01382368 Phase 4 Sildenafil
26 LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure Unknown status NCT00668408 Phase 4
27 The Efficacy and Safety of Salmeterol/Fluticasone Propionate vs Atropium/Albuterol in Patients COPD Unknown status NCT01243788 Phase 4 Salmeterol/Fluticasone Propionate
28 Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil Unknown status NCT00625079 Phase 4 sildenafil;sildenafil
29 Comparing Fluticasone-Salmeterol in Chronic Obstructive Pulmonary Disease (COPD) and Sleep Unknown status NCT00731770 Phase 4 fluticasone/salmeterol 250/50;placebo
30 Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD Unknown status NCT02197871 Phase 4
31 The Effects of Continuous Positive Airway Pressure on Overlap Syndrome Unknown status NCT00914264 Phase 4
32 AeriSeal System in Patients With Advanced Upper Lobe Predominant Emphysema and Collateral Ventilation Unknown status NCT01460108 Phase 4
33 Strategy to Improve Adherence of Roflumilast Unknown status NCT02018432 Phase 4 Roflumilast escalation dosage;Roflumilast conventional dosage
34 An Efficacy Study of BCS Clearing the Oral Colonized Bacterium in Hospitalized Patients With COPD Unknown status NCT02269800 Phase 4 Benzalkonium chloride solution;Normal saline
35 EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema Unknown status NCT00730301 Phase 4
36 Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography Unknown status NCT01361984 Phase 4 Nebulized arformoterol;Salmeterol
37 Preterm Infant Inhaled Albuterol Dosing Unknown status NCT02447250 Phase 4 Varied albuterol dose response
38 Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With Bosentan Unknown status NCT00625469 Phase 4 bosentan
39 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4 Racemic adrenaline;Isotonic saline
40 Reintroduction Regimens After Hepatitis During Anti-tuberculosis Treatment Unknown status NCT01395654 Phase 4 isoniazid, rifampin, pyrazinamide
41 Long Acting Phosphodiesterase 5 Inhibitors as Add-on Therapy for Patients With Pulmonary Hypertension Treated With Prostanoids. Unknown status NCT00705588 Phase 4 Tadalafil;Vardenafil
42 Metformin for Weight Control in Adolescents Taking Atypical Antipsychotics Unknown status NCT00845936 Phase 4 Metformin
43 Comparison of Low-Molecular-Weight Heparin (LMWH) and Unfractionated Heparin (UFH) in Combination With Thrombolytic Treatment of Acute Massive Pulmonary Thromboembolism Unknown status NCT01956955 Phase 4 enoxaparin ,alteplase, unfractionated heparin
44 Evaluation and Reconditioning of Marginal Lung Donors to Transplantation by ex Vivo Lung Perfusion Unknown status NCT01353105 Phase 4
45 Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis Unknown status NCT00560287 Phase 4
46 Safety Evaluation of Dexmedetomidine for EBUS-TBNA Unknown status NCT01381627 Phase 4 Remifentanil;Dexmedetomidine
47 Transfusion Strategies in Weaning Patients Unknown status NCT01256645 Phase 4
48 Evaluate the Effects of Formoterol and Beclomethasone Dipropionate Combination Therapy on Small Airways Function Unknown status NCT01466712 Phase 4 Tiotropium + formoterol/beclometasone;tiotropium + placebo
49 Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections Unknown status NCT02171338 Phase 4
50 Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. Unknown status NCT00331656 Phase 4

Search NIH Clinical Center for Lung Disease

Cochrane evidence based reviews: lung diseases

Genetic Tests for Lung Disease

Genetic tests related to Lung Disease:

id Genetic test Affiliating Genes
1 Disorder of Lung 29

Anatomical Context for Lung Disease

MalaCards organs/tissues related to Lung Disease:

39
Lung, Testes, Heart, Brain, Endothelial, Bone, Neutrophil

Publications for Lung Disease

Articles related to Lung Disease:

(show top 50) (show all 2364)
id Title Authors Year
1
Epidemiology of Nontuberculous Mycobacterial Lung Disease and Tuberculosis, Hawaii, USA. ( 28221128 )
2017
2
Scedosporium apiospermum Mycetoma in an Immunocompetent Patient without Prior Lung Disease. ( 28035880 )
2017
3
Predictors of granulomatous lymphocytic interstitial lung disease in common variable immunodeficiency. ( 28254202 )
2017
4
Exercise training improves exercise capacity and quality of life in people with interstitial lung disease [synopsis]. ( 28888691 )
2017
5
Myositis-associated Interstitial Lung Disease: Predictors of Failure of Conventional Treatment and Response to Tacrolimus in a US Cohort. ( 28864644 )
2017
6
Integrative Cardiopulmonary Ultrasound for Interstitial Lung Disease Assessment: Correlation between Lung Ultrasound Performance and Cardiac Involvement. ( 28073593 )
2017
7
Statins may be beneficial for patients with pulmonary hypertension secondary to lung diseases. ( 28932549 )
2017
8
Usefulness of lung ultrasound B-lines in connective tissue disease-associated interstitial lung disease: a literature review. ( 28923086 )
2017
9
Treatment of connective tissue disease-associated interstitial lung disease: the pulmonologist's point of view. ( 28704913 )
2017
10
Improvement of the initial stage of interstitial lung disease during psoriasis treatment with secukinumab. ( 28891081 )
2017
11
Association of anti-aminoacyl-transfer RNA synthetase antibody and anti-melanoma differentiation-associated gene 5 antibody with the therapeutic response of polymyositis/dermatomyositis-associated interstitial lung disease. ( 28012490 )
2017
12
Clinical significance of Aspergillus species isolated from respiratory specimens in patients with Mycobacterium avium complex lung disease. ( 28920166 )
2017
13
Interstitial Lung Disease Associated with Adult Niemann-Pick Disease Type B. ( 28601876 )
2017
14
Can we effectively use radiographic imaging and clinical parameters for making an earlier diagnosis of granulomatous interstitial lung disease in patients with common variable immunodeficiency? ( 28477784 )
2017
15
Predictors of granulomatous lymphocytic interstitial lung disease in common variable immunodeficiency: Methodological issues. ( 28890025 )
2017
16
End-stage cystic fibrosis lung disease is characterised by a diverse inflammatory pattern: an immunohistochemical analysis. ( 28069067 )
2017
17
Common variable immunodeficiency-associated granulomatous and lymphocytic interstitial lung disease successfully treated with a combination regimen of rituximab and azathioprine. ( 28736065 )
2017
18
Utilization of non-invasive imaging tools for assessment of peripheral skeletal muscle size and composition in chronic lung disease: A systematic review. ( 28947019 )
2017
19
Radiographic fibrosis score predicts survival in systemic sclerosis-associated interstitial lung disease. ( 28925574 )
2017
20
Mortality and Respiratory Failure After Thoracoscopic Lung Biopsy for Interstitial Lung Disease. ( 28527960 )
2017
21
Osimertinib-Induced Interstitial Lung Disease Presenting as Eosinophilic Pneumonia. ( 28748819 )
2017
22
Concomitant lung cancer and interstitial lung disease: A challenge in clinical practice. ( 28063797 )
2017
23
Interstitial Lung Disease Following Single-Agent Nanoparticle Albumin-Bound Paclitaxel Treatment in Patients with Advanced Non-Small Cell Lung Cancer. ( 28878650 )
2017
24
Chronic lung disease in common variable immune deficiency (CVID): A pathophysiological role for microbial and non-B cell immune factors. ( 28068853 )
2017
25
Respiratory bronchiolitis-associated interstitial lung disease - an unexpected form of idiopathic interstitial pneumonia in a young male. ( 28523329 )
2017
26
Rapidly progressive interstitial lung disease due to anti-MDA-5 antibody-positive clinically amyopathic dermatomyositis complicated with cervical cancer: Successful treatment with direct hemoperfusion using polymyxin B-immobilized fiber column therapy. ( 27995057 )
2017
27
Mycobacterial Characteristics and Treatment Outcomes in Mycobacterium abscessus Lung Disease. ( 28011608 )
2017
28
Mild pulmonary emphysema a risk factor for interstitial lung disease when using cetuximab for squamous cell carcinoma of the head and neck. ( 28741444 )
2017
29
Combined methylmalonic acidemia and homocysteinemia presenting predominantly with late-onset diffuse lung disease: a case series of four patients. ( 28327205 )
2017
30
An unusual case of interstitial lung disease in a patient with cardiopulmonary syndrome as the initial presentation of Erdheim-Chester disease. ( 28739622 )
2017
31
Hypertonic saline in patients with primary ciliary dyskinesia: on the road to evidence-based treatment for a rare lung disease. ( 28232418 )
2017
32
First Spontaneous Pneumothorax: Time for Screening High-Resolution Computed Tomographic Imaging to Look for Cystic Lung Disease? ( 28035875 )
2017
33
Farmer's lung disease: Analysis of 75 cases. ( 28587854 )
2017
34
Lung disease caused by ABCA3 mutations. ( 27516224 )
2017
35
FDG PET-CT imaging of therapeutic response in granulomatous lymphocytic interstitial lung disease (GLILD) in common variable immunodeficiency (CVID). ( 27896807 )
2017
36
Meta-analysis of the incidence and risks of interstitial lung disease and QTc prolongation in non-small-cell lung cancer patients treated with ALK inhibitors. ( 28915678 )
2017
37
Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates. ( 28052185 )
2017
38
Extracorporeal Membrane Oxygenation for End-Stage Interstitial Lung Disease With Secondary Pulmonary Hypertension at Rest and Exercise: Insights From Simulation Modeling. ( 28863039 )
2017
39
Editorial: Chronic Suppurative Lung Disease and Bronchiectasis in Children and Adolescents. ( 28929095 )
2017
40
Characteristics associated with progression in patients with of nontuberculous mycobacterial lung disease : a prospective cohort study. ( 28056937 )
2017
41
Positive Association between ANKRD55 Polymorphism 7731626 and Dermatomyositis/Polymyositis with Interstitial Lung Disease in Chinese Han Population. ( 28470010 )
2017
42
Progression and Treatment Outcomes of Lung Disease Caused by Mycobacterium abscessus and Mycobacterium massiliense. ( 28011609 )
2017
43
A Laboratory-based Analysis of Nontuberculous Mycobacterial Lung Disease in Japan from 2012 to 2013. ( 27788025 )
2017
44
Dynamic expression of transformating growth factor-I^1 and caveolin-1 in the lung of Bleomycin-induced interstitial lung disease. ( 28932540 )
2017
45
Autoantibody to scaffold attachment factor B (SAFB): A novel connective tissue disease-related autoantibody associated with interstitial lung disease. ( 27682649 )
2017
46
Extraction of the subpleural lung region from computed tomography images to detect interstitial lung disease. ( 28936704 )
2017
47
Pathologic Separation of Chronic Hypersensitivity Pneumonitis From Fibrotic Connective Tissue Disease-associated Interstitial Lung Disease. ( 28614213 )
2017
48
Neutrophil extracellular traps may contribute to interstitial lung disease associated with anti-MDA5 autoantibody positive dermatomyositis. ( 28842784 )
2017
49
Hypomyopathic dermatomyositis associated with interstitial lung disease and good response to mycophenolate mofetil: case-based review. ( 28488124 )
2017
50
Emphysema in active farmer's lung disease. ( 28614400 )
2017

Variations for Lung Disease

Expression for Lung Disease

Search GEO for disease gene expression data for Lung Disease.

Pathways for Lung Disease

Pathways related to Lung Disease according to GeneCards Suite gene sharing:

(show all 18)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.61 ABCA3 CFTR COPA CXCL8 IFIH1 MUC5B
2
Show member pathways
12.71 CXCL8 IL1B SFTPA2 SFTPD TNF
3
Show member pathways
12.16 CFTR CXCL8 IL1B MUC5B TNF
4
Show member pathways
11.85 CFTR CXCL8 IL1B SFTPA1 SFTPD TNF
5 11.74 IL1B ITGA3 TNF
6 11.73 CXCL8 IL1B TNF
7 11.71 CXCL8 IL1B TNF
8
Show member pathways
11.7 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD
9 11.68 CXCL8 IL1B TNF
10 11.54 CXCL8 IL1B SFTPA1 SFTPA2 TNF
11
Show member pathways
11.5 CXCL8 IL1B TNF
12 11.43 CXCL8 IL1B TNF
13
Show member pathways
11.37 SERPINA1 SFTPA1 SFTPA2 SFTPD
14 11.36 CXCL8 IL1B TNF
15 11.34 CXCL8 IL1B TNF
16
Show member pathways
11.27 IL1B TNF TSC2
17 11.08 CXCL8 IL1B MUC5B SERPINA1 SFTPA1 SFTPA2
18
Show member pathways
11.07 ABCA3 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD

GO Terms for Lung Disease

Cellular components related to Lung Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.97 ABCA3 COPA CXCL8 ELANE IL1B MUC5B
2 endoplasmic reticulum membrane GO:0005789 9.91 CFTR COPA SFTPA1 SFTPA2 SFTPB SFTPC
3 collagen trimer GO:0005581 9.63 SFTPA1 SFTPA2 SFTPD
4 multivesicular body lumen GO:0097486 9.43 SFTPB SFTPC
5 alveolar lamellar body GO:0097208 9.4 ABCA3 SFTPB
6 clathrin-coated endocytic vesicle GO:0045334 9.35 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD
7 TSC1-TSC2 complex GO:0033596 9.32 TSC1 TSC2
8 lamellar body GO:0042599 9.02 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD
9 extracellular region GO:0005576 10.03 COPA CXCL8 ELANE IL1B MUC5B SERPINA1

Biological processes related to Lung Disease according to GeneCards Suite gene sharing:

(show all 16)
id Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.83 ELANE IL1B ITGA3 TNF
2 toll-like receptor signaling pathway GO:0002224 9.63 SFTPA1 SFTPA2 SFTPD
3 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.58 IL1B TERT TNF
4 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.56 IL1B TNF
5 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.55 IL1B TNF
6 positive regulation of chemokine biosynthetic process GO:0045080 9.54 IL1B TNF
7 protein kinase B signaling GO:0043491 9.54 IL1B TNF TSC2
8 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.51 ELANE TNF
9 cellular protein metabolic process GO:0044267 9.5 ABCA3 SERPINA1 SFTPA1 SFTPA2 SFTPB SFTPC
10 regulation of establishment of endothelial barrier GO:1903140 9.49 IL1B TNF
11 positive regulation of fever generation GO:0031622 9.48 IL1B TNF
12 sequestering of triglyceride GO:0030730 9.43 IL1B TNF
13 positive regulation of phagocytosis GO:0050766 9.43 IL1B SFTPD TNF
14 negative regulation of insulin receptor signaling pathway GO:0046627 9.33 IL1B TSC1 TSC2
15 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.32 IL1B TNF
16 respiratory gaseous exchange GO:0007585 9.02