MCID: LNG039
MIFTS: 35

Lung Squamous Cell Carcinoma malady

Cancer diseases, Skin diseases, Respiratory diseases categories

Summaries for Lung Squamous Cell Carcinoma

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung... more...

MalaCards: Lung Squamous Cell Carcinoma, also known as squamous cell carcinoma of lung, is related to lung adenocarcinoma and lung cancer. An important gene associated with Lung Squamous Cell Carcinoma is MIR218-2 (microRNA 218-2), and among its related pathways are miRs in Muscle Cell Differentiation and SRF and miRs in Smooth Muscle Differentiation and Proliferation. Affiliated tissues include lung, bone and brain.

Aliases & Classifications for Lung Squamous Cell Carcinoma

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 46Novoseek, 41NCIt, 59SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases, Respiratory diseases


Aliases & Descriptions:

lung squamous cell carcinoma 9 11
squamous cell carcinoma of lung 9 63
epidermoid cell carcinoma of the lung 9
squamous cell lung cancer 46


External Ids:

Disease Ontology9 DOID:3907
SNOMED-CT59 254634000
NCIt41 C3493

Related Diseases for Lung Squamous Cell Carcinoma

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Lung Squamous Cell Carcinoma:



Diseases related to lung squamous cell carcinoma

Symptoms for Lung Squamous Cell Carcinoma

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Drugs & Therapeutics for Lung Squamous Cell Carcinoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Lung Squamous Cell Carcinoma

Drug clinical trials:

Search ClinicalTrials for Lung Squamous Cell Carcinoma

Search NIH Clinical Center for Lung Squamous Cell Carcinoma

Search CenterWatch for Lung Squamous Cell Carcinoma

Genetic Tests for Lung Squamous Cell Carcinoma

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Anatomical Context for Lung Squamous Cell Carcinoma

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34MalaCards
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MalaCards organs/tissues related to Lung Squamous Cell Carcinoma:

34
Lung, Bone, Brain, Small intestine, Colon, Breast, Skin, T cells, B cells

Animal Models for Lung Squamous Cell Carcinoma or affiliated genes

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Publications for Lung Squamous Cell Carcinoma

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53PubMed
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Articles related to Lung Squamous Cell Carcinoma:

(show top 50)    (show all 146)
idTitleAuthorsYear
1
A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma. (23934444)
2013
2
PIK3CA mutation in Chinese patients with lung squamous cell carcinoma. (23997528)
2013
3
Comprehensive Analysis of Oncogenic Mutations in Lung Squamous Cell Carcinoma with Minor Glandular Component. (24158231)
2013
4
Bone marrow-derived cells contribute to NDEA-induced lung squamous cell carcinoma. (23055190)
2013
5
Terminal N-Acetylgalactosamine-Specific Leguminous Lectin from Wisteria japonica as a Probe for Human Lung Squamous Cell Carcinoma. (24349556)
2013
6
Lung squamous cell carcinoma arising in a patient with adult-onset recurrent respiratory papillomatosis. (23110763)
2013
7
The pivotal role of IKKI+ in the development of spontaneous lung squamous cell carcinomas. (23597566)
2013
8
Lung Squamous Cell Carcinoma in Pulmonary Alveolar Proteinosis. (24200658)
2013
9
Expression of insulin-like growth factor 2 mRNA-binding protein 3 expression and analysis of prognosis in the patients with lung squamous cell carcinoma]. (23837977)
2013
10
Lung squamous cell carcinoma combined with tuberculous pleurisy. (23075740)
2012
11
Prognostic impact of CD204-positive macrophages in lung squamous cell carcinoma: possible contribution of Cd204-positive macrophages to the tumor-promoting microenvironment. (23154550)
2012
12
Increased NRF2 gene (NFE2L2) copy number correlates with mutations in lung squamous cell carcinomas. (22614957)
2012
13
miRNAs expression profiling to distinguish lung squamous-cell carcinoma from adenocarcinoma subtypes. (22618509)
2012
14
Giant gingival pseudoepitheliomatous hyperplasia in lung squamous cell carcinoma. (22801162)
2012
15
DeltaN TP63 reactivation, epithelial phenotype maintenance, and survival in lung squamous cell carcinoma. (21986963)
2012
16
MS4A1 dysregulation in asbestos-related lung squamous cell carcinoma is due to CD20 stromal lymphocyte expression. (22514692)
2012
17
Fibrous stroma is associated with poorer prognosis in lung squamous cell carcinoma patients. (21849853)
2011
18
Vulvar skin metastasis of lung squamous cell carcinoma. (22148044)
2011
19
A case of lung squamous cell carcinoma with metastases to the duodenum and small intestine. (22026313)
2011
20
The expression and significance of RKIP in lung squamous cell carcinoma tissues]. (21426659)
2011
21
Immunolocalization of glycodelin in human adenocarcinoma of the lung, squamous cell carcinoma of the lung and lung metastases of colonic adenocarcinoma. (21168900)
2011
22
SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas. (20126410)
2010
23
Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. (20668658)
2010
24
The role of microRNA in human lung squamous cell carcinoma. (20620595)
2010
25
Significance of S100A4 as a prognostic marker of lung squamous cell carcinoma. (19596927)
2009
26
Reconstitution of amphiregulin-epidermal growth factor receptor signaling in lung squamous cell carcinomas activates PTHrP gene expression and contributes to cancer-mediated diseases of the bone. (19825997)
2009
27
Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs. (19584077)
2009
28
Triosephosphate isomerase and peroxiredoxin 6, two novel serum markers for human lung squamous cell carcinoma. (19737146)
2009
29
Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis. (18301992)
2008
30
Expression of the WT1 gene -KTS domain isoforms suppresses the invasive ability of human lung squamous cell carcinoma cells. (18202757)
2008
31
2-D difference gel electrophoresis of the lung squamous cell carcinoma versus normal sera demonstrates consistent alterations in the levels of ten specific proteins. (18041032)
2007
32
High-level expression of CD109 is frequently detected in lung squamous cell carcinomas. (17922683)
2007
33
ERBB2 kinase domain mutation in the lung squamous cell carcinoma. (16029927)
2006
34
COX-2 expression during early lung squamous cell carcinoma oncogenesis. (16055866)
2005
35
Identification of differentially expressed genes in human lung squamous cell carcinoma using suppression subtractive hybridization. (15246564)
2004
36
Molecular cloning, identification and analysis of lung squamous cell carcinoma-related genes. (12445744)
2002
37
A p53 homologue and a novel serine proteinase inhibitor are over-expressed in lung squamous cell carcinoma. (11714533)
2001
38
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma. (10732758)
2000
39
Tissue polypeptide specific antigen and squamous cell carcinoma antigen for early prediction of recurrence in lung squamous cell carcinoma. (10773133)
2000
40
The expression of Mdm2 protein and p53 mutation in lung squamous cell carcinomas and their clinicopathological significance]. (11812371)
1999
41
Pulmonary alveolar proteinosis with lung squamous cell carcinoma. (10464867)
1999
42
Increased NM23: MTS1 ratio inversely correlated with metastasis behaviour in human lung squamous cell carcinoma. (9066685)
1997
43
Lung squamous cell carcinoma producing both parathyroid hormone-related peptide and granulocyte colony stimulating factor. (8809885)
1996
44
Glutathione S transferase Pi is a powerful indicator in chemotherapy of human lung squamous-cell carcinoma. (8578019)
1995
45
Regulation of parathyroid hormone-related protein production in a human lung squamous cell carcinoma line. (7829996)
1994
46
Association and dissociation of a protease and its inhibitor on the surface of lung squamous cell carcinoma cells. (8352526)
1993
47
Cytogenetic comparison of two poorly differentiated human lung squamous cell carcinoma lines. (1581877)
1992
48
Characterization of the antigen identified by Po66. A monoclonal antibody raised against a lung squamous cell carcinoma. (2541906)
1989
49
A monoclonal antibody (Po66) directed against human lung squamous cell carcinoma immunolocalization of tumour xenografts in nude mice. (3297323)
1987
50
Generation of monoclonal antibodies against human lung squamous cell carcinoma and adenocarcinoma using mice rendered tolerant to normal human lung. (3731100)
1986

Variations for Lung Squamous Cell Carcinoma

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Expression for genes affiliated with Lung Squamous Cell Carcinoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lung Squamous Cell Carcinoma

Search GEO for disease gene expression data for Lung Squamous Cell Carcinoma.

Pathways for genes affiliated with Lung Squamous Cell Carcinoma

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51PathCards, 39NCBI BioSystems Database, 31KEGG
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Pathways related to Lung Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8MIR133A2, MIR133A1
29.8MIR133A2, MIR133A1
39.8MIR133A2, MIR133A1
49.4MIR31, MIR133A2, MIR133A1

Compounds for genes affiliated with Lung Squamous Cell Carcinoma

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GO Terms for genes affiliated with Lung Squamous Cell Carcinoma

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17Gene Ontology
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Cellular components related to Lung Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lysosomeGO:0057649.5HYAL3, NAPSA

Products for genes affiliated with Lung Squamous Cell Carcinoma

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Sources for Lung Squamous Cell Carcinoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet