MCID: LNG039
MIFTS: 37

Lung Squamous Cell Carcinoma malady

Cancer diseases, Skin diseases, Respiratory diseases categories
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Summaries for Lung Squamous Cell Carcinoma

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Wikipedia:65 Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung... more...

MalaCards based summary: Lung Squamous Cell Carcinoma, also known as epidermoid cell carcinoma of the lung, is related to lung adenocarcinoma and adenocarcinoma. An important gene associated with Lung Squamous Cell Carcinoma is MIR218-2 (microRNA 218-2), and among its related pathways are miRs in Muscle Cell Differentiation and SRF and miRs in Smooth Muscle Differentiation and Proliferation. Affiliated tissues include lung, bone and lymph node.

Disease Ontology:8 A non-small cell lung carcinoma that has material basis in the squamous cell.

Aliases & Classifications for Lung Squamous Cell Carcinoma

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Lung Squamous Cell Carcinoma, Aliases & Descriptions:

Name: Lung Squamous Cell Carcinoma 8 10
Epidermoid Cell Carcinoma of the Lung 8 62
 
Squamous Cell Carcinoma of Lung 62
Squamous Cell Lung Cancer 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Skin diseases, Respiratory diseases


External Ids:

Disease Ontology8 DOID:3907
SNOMED-CT57 254634000
NCIt39 C3493

Related Diseases for Lung Squamous Cell Carcinoma

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Graphical network of the top 20 diseases related to Lung Squamous Cell Carcinoma:



Diseases related to lung squamous cell carcinoma

Symptoms for Lung Squamous Cell Carcinoma

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Drugs & Therapeutics for Lung Squamous Cell Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Lung Squamous Cell Carcinoma

Search NIH Clinical Center for Lung Squamous Cell Carcinoma

Genetic Tests for Lung Squamous Cell Carcinoma

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Anatomical Context for Lung Squamous Cell Carcinoma

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MalaCards organs/tissues related to Lung Squamous Cell Carcinoma:

32
Lung, Bone, Lymph node, Brain, Small intestine, Breast, Skin, T cells, B cells, Endothelial

Animal Models for Lung Squamous Cell Carcinoma or affiliated genes

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Publications for Lung Squamous Cell Carcinoma

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Articles related to Lung Squamous Cell Carcinoma:

(show top 50)    (show all 170)
idTitleAuthorsYear
1
Keratoacanthoma accompanied by multiple lung squamous cell carcinomas developing in a renal transplant recipient. (25120468)
2014
2
Prognostic significance of PIK3CA and SOX2 in Asian patients with lung squamous cell carcinoma. (25384882)
2014
3
Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients. (25250788)
2014
4
Dietary diindolylmethane suppresses inflammation-driven lung squamous cell carcinoma in mice. (25403850)
2014
5
Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma. (24477565)
2014
6
Immunophenotypic features of metastatic lymph node tumors to predict recurrence in N2 lung squamous cell carcinoma. (24814677)
2014
7
Lung squamous cell carcinoma metastasizing to the nasopharynx following bronchoscopy intervention therapies: a case report. (24673971)
2014
8
9q33.3, a stress-related chromosome region, contributes to reducing lung squamous cell carcinoma risk. (24926550)
2014
9
Erythrocyte fatty acids as potential biomarkers in the diagnosis of advanced lung adenocarcinoma, lung squamous cell carcinoma, and small cell lung cancer. (24926094)
2014
10
Hsa-mir-182 downregulates RASA1 and suppresses lung squamous cell carcinoma cell proliferation. (24600991)
2014
11
Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients. (24323028)
2014
12
A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma. (23934444)
2013
13
Genetic variation in SIRT1 affects susceptibility of lung squamous cell carcinomas in former uranium miners from the Colorado plateau. (23354305)
2013
14
PIK3CA mutation in Chinese patients with lung squamous cell carcinoma. (23997528)
2013
15
Comprehensive Analysis of Oncogenic Mutations in Lung Squamous Cell Carcinoma with Minor Glandular Component. (24158231)
2013
16
Bone marrow-derived cells contribute to NDEA-induced lung squamous cell carcinoma. (23055190)
2013
17
Terminal N-Acetylgalactosamine-Specific Leguminous Lectin from Wisteria japonica as a Probe for Human Lung Squamous Cell Carcinoma. (24349556)
2013
18
Lung squamous cell carcinoma arising in a patient with adult-onset recurrent respiratory papillomatosis. (23110763)
2013
19
The pivotal role of IKKI+ in the development of spontaneous lung squamous cell carcinomas. (23597566)
2013
20
Lung squamous cell carcinoma combined with tuberculous pleurisy. (23075740)
2012
21
Prognostic impact of CD204-positive macrophages in lung squamous cell carcinoma: possible contribution of Cd204-positive macrophages to the tumor-promoting microenvironment. (23154550)
2012
22
Increased NRF2 gene (NFE2L2) copy number correlates with mutations in lung squamous cell carcinomas. (22614957)
2012
23
miRNAs expression profiling to distinguish lung squamous-cell carcinoma from adenocarcinoma subtypes. (22618509)
2012
24
Giant gingival pseudoepitheliomatous hyperplasia in lung squamous cell carcinoma. (22801162)
2012
25
DeltaN TP63 reactivation, epithelial phenotype maintenance, and survival in lung squamous cell carcinoma. (21986963)
2012
26
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma. (22006338)
2011
27
Fibrous stroma is associated with poorer prognosis in lung squamous cell carcinoma patients. (21849853)
2011
28
Vulvar skin metastasis of lung squamous cell carcinoma. (22148044)
2011
29
A case of lung squamous cell carcinoma with metastases to the duodenum and small intestine. (22026313)
2011
30
The expression and significance of RKIP in lung squamous cell carcinoma tissues]. (21426659)
2011
31
SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas. (20126410)
2010
32
Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. (20668658)
2010
33
The role of microRNA in human lung squamous cell carcinoma. (20620595)
2010
34
Significance of S100A4 as a prognostic marker of lung squamous cell carcinoma. (19596927)
2009
35
Reconstitution of amphiregulin-epidermal growth factor receptor signaling in lung squamous cell carcinomas activates PTHrP gene expression and contributes to cancer-mediated diseases of the bone. (19825997)
2009
36
Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs. (19584077)
2009
37
Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis. (18301992)
2008
38
2-D difference gel electrophoresis of the lung squamous cell carcinoma versus normal sera demonstrates consistent alterations in the levels of ten specific proteins. (18041032)
2007
39
ERBB2 kinase domain mutation in the lung squamous cell carcinoma. (16029927)
2006
40
Molecular cloning, identification and analysis of lung squamous cell carcinoma-related genes. (12445744)
2002
41
A p53 homologue and a novel serine proteinase inhibitor are over-expressed in lung squamous cell carcinoma. (11714533)
2001
42
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma. (10732758)
2000
43
The expression of Mdm2 protein and p53 mutation in lung squamous cell carcinomas and their clinicopathological significance]. (11812371)
1999
44
Pulmonary alveolar proteinosis with lung squamous cell carcinoma. (10464867)
1999
45
Lung squamous cell carcinoma producing both parathyroid hormone-related peptide and granulocyte colony stimulating factor. (8809885)
1996
46
Regulation of parathyroid hormone-related protein production in a human lung squamous cell carcinoma line. (7829996)
1994
47
Cytogenetic comparison of two poorly differentiated human lung squamous cell carcinoma lines. (1581877)
1992
48
Characterization of the antigen identified by Po66. A monoclonal antibody raised against a lung squamous cell carcinoma. (2541906)
1989
49
A monoclonal antibody (Po66) directed against human lung squamous cell carcinoma immunolocalization of tumour xenografts in nude mice. (3297323)
1987
50
Generation of monoclonal antibodies against human lung squamous cell carcinoma and adenocarcinoma using mice rendered tolerant to normal human lung. (3731100)
1986

Variations for Lung Squamous Cell Carcinoma

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Expression for genes affiliated with Lung Squamous Cell Carcinoma

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Expression patterns in normal tissues for genes affiliated with Lung Squamous Cell Carcinoma

Search GEO for disease gene expression data for Lung Squamous Cell Carcinoma.

Pathways for genes affiliated with Lung Squamous Cell Carcinoma

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Pathways related to Lung Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8MIR133A2, MIR133A1
29.8MIR133A2, MIR133A1
39.8MIR133A2, MIR133A1
49.4MIR31, MIR133A2, MIR133A1

Compounds for genes affiliated with Lung Squamous Cell Carcinoma

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GO Terms for genes affiliated with Lung Squamous Cell Carcinoma

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Cellular components related to Lung Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lysosomeGO:0057649.5HYAL3, NAPSA

Products for genes affiliated with Lung Squamous Cell Carcinoma

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  • Antibodies
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Sources for Lung Squamous Cell Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet