MCID: LTM002
MIFTS: 30

Luteoma malady

Summaries for Luteoma

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63Wikipedia, 32MalaCards
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Wikipedia:63 A luteoma is a tumor that occurs in the ovaries during pregnancy. It is associated with an increases of... more...

MalaCards: Luteoma, also known as leuteoma of pregnancy, is related to pseudohermaphroditism and congenital adrenal hyperplasia. An important gene associated with Luteoma is CYP21A2 (cytochrome P450, family 21, subfamily A, polypeptide 2). The compounds nafarelin and 17-hydroxypregnenolone have been mentioned in the context of this disorder. Affiliated tissues include ovary and uterus.

Aliases & Classifications for Luteoma

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 39NCIt
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Aliases & Descriptions:

luteoma 8 10 44 60
leuteoma of pregnancy 8
luteoma of pregnancy 8


External Ids:

Disease Ontology8 DOID:7880
NCIt39 C40445

Related Diseases for Luteoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Luteoma:



Diseases related to luteoma

Clinical Features for Luteoma

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Drugs & Therapeutics for Luteoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Luteoma

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Anatomical Context for Luteoma

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32MalaCards
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MalaCards organs/tissues related to Luteoma:

32
Ovary, Uterus

Animal Models for Luteoma or affiliated genes

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Publications for Luteoma

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50PubMed
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Articles related to Luteoma:

(show top 50)    (show all 68)
idTitleAuthorsYear
1
Pregnancy Luteoma: A Study of 20 Cases on the Occasion of the 50th Anniversary of its Description by Dr William H. Sternberg, With an Emphasis on the Common Presence of Follicle-like Spaces and Their Diagnostic Implications. (24335664)
2014
2
Luteoma of Pregnancy Associated with Near Complete Virilization of Genetically Female Twins. (24126228)
2013
3
Unilateral luteoma of pregnancy mimicking a malignant ovarian mass on magnetic resonance and ultrasound. (19243065)
2009
4
Luteoma-induced fetal virilization. (20149054)
2009
5
Boy born after gender preselection following successive gestational androgen excess of maternal luteoma and female disorders of sex development. (19110243)
2009
6
Stromal luteoma and nodular hyperthecosis of the bilateral ovaries associated with atypical endometrial hyperplasia of the uterus. (19883437)
2009
7
Maternal virilization due to luteoma associated with delayed lactation. (18635167)
2008
8
Pregnancy luteoma presenting as ovarian torsion with rupture and intra-abdominal bleeding. (18362993)
2008
9
Stromal luteoma: report of a rare case. (17883070)
2007
10
Krukenberg tumor mimicking pregnancy luteoma. (17852427)
2007
11
Maternal luteoma of pregnancy presenting with virilization of the female infant. (17915067)
2007
12
Luteoma of pregnancy. (17000514)
2006
13
MR imaging of pregnancy luteoma: a case report and correlation with the clinical features. (15782020)
2005
14
Prenatal diagnosis of female pseudohermaphroditism associated with bilateral luteoma of pregnancy: case report. (11870143)
2002
15
Luteoma of pregnancy: sonographic findings in two cases. (11127014)
2000
16
Luteoma of pregnancy presenting with massive ascites and markedly elevated CA 125. (10546765)
1999
17
GnRH receptors and GnRH endocrine effects on luteoma cells. (9225131)
1997
18
Ovarian steroid cell tumor resembling luteoma associated with hyperadrenocorticism (Cushing's disease) in a dog. (9150550)
1997
19
A gonadotrophin dependent stromal luteoma: a rare cause of post-menopausal virilization. (8548951)
1995
20
Luteoma of pregnancy: masculinisation of a female fetus prevented by placental aromatisation. (1335753)
1992
21
Stromal luteoma of the ovary: a clinicopathological analysis of 25 cases. (2826353)
1987
22
High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma. (6094939)
1984
23
Luteoma of pregnancy. (6330914)
1984
24
Incidental pregnancy luteoma associated with ectopic tubo-ovarian pregnancy: evidence in favor of origin from theca interna of an atretic follicle. (233743)
1978
25
Differential maternal-fetal response to androgenizing luteoma or hyperreactio luteinalis. (205819)
1978
26
Properties of human gonadotrophins eluted from human corpus luteum and mouse luteoma LH-HCG receptors. (188284)
1977
27
Virilization of mother and fetus associated with luteoma of pregnancy: a case report with endocrinologic studies. (197851)
1977
28
Letter: Luteoma of pregnancy. (170823)
1975
29
Luteoma of pregnancy: report of a case and review of the literature. (163309)
1975
30
Luteoma of pregnancy: case report. (163588)
1975
31
Remission of acanthosis nigricans associated with polycystic ovarian disease and a stromal luteoma. (4360917)
1974
32
Virilizing luteoma of pregnancy. Report of a case with measurements of testosterone and testosterone binding in plasma. (4346682)
1973
33
Gonadotropin receptor of a mouse luteoma: interactions with luteinizing hormone (LH) and its and subunits. (4351508)
1973
34
Luteoma in pregnancy. (4375468)
1973
35
Luteoma of pregnancy. (4335590)
1972
36
Transplantable luteoma of the mouse. An ultrastructural and biochemical study. (4338338)
1972
37
Luteoma of pregnancy. (4319381)
1970
38
Luteoma of pregnancy: recurrent or persistent? (5366428)
1969
39
Luteoma of pregnancy: steroidogenic and morphologic considerations. (4307340)
1969
40
In vivo and in vitro studies of steroid production by a luteoma and an adrenal cortical carcinoma in mice. (4304996)
1969
41
Ambiguous genitals in a female infant associated with luteoma of pregnancy. Report of a case. (4298215)
1968
42
Steroid content and synthesis in a virilizing luteoma. (4290318)
1967
43
Luteoma of pregnancy. (4286956)
1966
44
STROMAL LUTEOMA OF THE OVARY. A DISTINCTIVE TYPE OF LIPOID-CELL TUMOR. (14176990)
1964
45
PSEUDOPRECOCITY IN AN INFANT DUE TO A LUTEOMA OF THE OVARY. (14065997)
1963
46
Sexual precocity due to estrogen- and progesterone-producing organoid luteoma of the ovary. (13300437)
1955
47
Neutral steroids in the urine of a patient with a luteoma of the ovary. (13069593)
1953
48
Evolution of luteoma in intrasplenic ovarian grafts in the guinea-pig. (13081901)
1953
49
Luteoma of the ovary. (14918776)
1952
50
Transplantability of induced granulosa cell tumors and of luteoma in mice; secondary effects of these growths. (21024146)
1946

Genetic Variations for Luteoma

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Expression for genes affiliated with Luteoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Luteoma

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Pathways for genes affiliated with Luteoma

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Compounds for genes affiliated with Luteoma

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44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 24HMDB, 49PharmGKB
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Compounds related to Luteoma according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1nafarelin44 59 28 1112.7CYP21A2, CGA
217-hydroxypregnenolone449.7CGA, CYP21A2
311 deoxycortisol449.7CYP21A2, CGA
4leuprolide acetate449.7CYP21A2, CGA
5clomiphene citrate449.7CGA, CYP21A2
617-hydroxyprogesterone44 2410.6CYP21A2, CGA
73beta-hydroxysteroid449.6CGA, CYP21A2
8dehydroepiandrosterone sulfate449.6CYP21A2, CGA
917beta-hydroxysteroid449.6CYP21A2, CGA
10phenytoin44 49 28 1112.6CGA, CYP21A2
11androstenedione44 2410.5CYP21A2, CGA
12thyroxine44 2410.4CYP21A2, CGA
13deoxyribonucleic acid449.4SRY, CYP21A2
14carbon449.3CGA, CYP21A2
15ribonucleic acid449.3CYP21A2, CGA
16biotin44 11 2411.3CYP21A2, SRY
17agarose449.2SRY, CYP21A2
18gnrh449.2CYP21A2, CGA
19epinephrine44 11 2411.0CYP21A2, CGA
20dihydrotestosterone44 28 11 2411.9SRY, CYP21A2, CGA
21estradiol44 11 2410.8SRY, CYP21A2, CGA
22testosterone44 59 11 2411.7SRY, CYP21A2, CGA
23steroid448.7CGA, CYP21A2, SRY

GO Terms for genes affiliated with Luteoma

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Products for genes affiliated with Luteoma

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  • Antibodies
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Sources for Luteoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet