MCID: LTM002
MIFTS: 32

Luteoma malady

Reproductive diseases category
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Summaries for Luteoma

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Wikipedia:65 A luteoma is a tumor that occurs in the ovaries during pregnancy. It is associated with an increases of... more...

MalaCards based summary: Luteoma, also known as leuteoma of pregnancy, is related to congenital adrenal hyperplasia and testicular disease. An important gene associated with Luteoma is CYP21A2 (cytochrome P450, family 21, subfamily A, polypeptide 2), and among its related pathways is Metabolism of steroid hormones and vitamin D. The compounds deoxyribonucleic acid and biotin have been mentioned in the context of this disorder. Affiliated tissues include ovary and uterus.

Aliases & Classifications for Luteoma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 39NCIt
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Luteoma, Aliases & Descriptions:

Name: Luteoma 8 10 44 62
Leuteoma of Pregnancy 8 62
 
Luteoma of Pregnancy 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


External Ids:

Disease Ontology8 DOID:7880
NCIt39 C40445

Related Diseases for Luteoma

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Graphical network of the top 20 diseases related to Luteoma:



Diseases related to luteoma

Symptoms for Luteoma

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Drugs & Therapeutics for Luteoma

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Drug clinical trials:

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Search NIH Clinical Center for Luteoma

Genetic Tests for Luteoma

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Anatomical Context for Luteoma

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MalaCards organs/tissues related to Luteoma:

32
Ovary, Uterus

Animal Models for Luteoma or affiliated genes

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Publications for Luteoma

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Articles related to Luteoma:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
Pregnancy Luteoma: A Study of 20 Cases on the Occasion of the 50th Anniversary of its Description by Dr William H. Sternberg, With an Emphasis on the Common Presence of Follicle-like Spaces and Their Diagnostic Implications. (24335664)
2014
2
Bilateral pregnancy luteoma: a case report. (25337317)
2014
3
Stromal luteoma of the ovary: A rare ovarian pathology. (25140903)
2014
4
Unilateral luteoma of pregnancy mimicking a malignant ovarian mass on magnetic resonance and ultrasound. (19243065)
2009
5
Luteoma-induced fetal virilization. (20149054)
2009
6
Boy born after gender preselection following successive gestational androgen excess of maternal luteoma and female disorders of sex development. (19110243)
2009
7
Maternal virilization due to luteoma associated with delayed lactation. (18635167)
2008
8
Pregnancy luteoma presenting as ovarian torsion with rupture and intra-abdominal bleeding. (18362993)
2008
9
Stromal luteoma: report of a rare case. (17883070)
2007
10
Krukenberg tumor mimicking pregnancy luteoma. (17852427)
2007
11
Maternal luteoma of pregnancy presenting with virilization of the female infant. (17915067)
2007
12
Granulosa theca cell tumor with luteoma in the ovary of a bonnet monkey (Macaca radiata). (16053501)
2005
13
MR imaging of pregnancy luteoma: a case report and correlation with the clinical features. (15782020)
2005
14
Magnetic resonance imaging of pregnancy luteoma. (12703004)
2003
15
Prenatal diagnosis of female pseudohermaphroditism associated with bilateral luteoma of pregnancy: case report. (11870143)
2002
16
Features of Antley-Bixler syndrome in an infant born to a mother with pregnancy luteoma. (10664233)
2000
17
Congenital adrenal hyperplasia associated with maternal pregnancy luteoma and the Antley-Bixler syndrome. (10726707)
2000
18
Luteoma of pregnancy presenting with massive ascites and markedly elevated CA 125. (10546765)
1999
19
Pregnancy luteoma with granulosa cell proliferation: an unusual hyperplastic lesion arising in pregnancy and mimicking an ovarian neoplasia. (10631723)
1999
20
GnRH receptors and GnRH endocrine effects on luteoma cells. (9225131)
1997
21
Luteoma of pregnancy: masculinisation of a female fetus prevented by placental aromatisation. (1335753)
1992
22
High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma. (6094939)
1984
23
Luteoma of pregnancy. (6330914)
1984
24
In vivo steroid studies in luteoma of pregnancy. (6283444)
1982
25
A case of virilizing luteoma. (6244616)
1980
26
Incidental pregnancy luteoma associated with ectopic tubo-ovarian pregnancy: evidence in favor of origin from theca interna of an atretic follicle. (233743)
1978
27
Differential maternal-fetal response to androgenizing luteoma or hyperreactio luteinalis. (205819)
1978
28
Properties of human gonadotrophins eluted from human corpus luteum and mouse luteoma LH-HCG receptors. (188284)
1977
29
Virilization of mother and fetus associated with luteoma of pregnancy: a case report with endocrinologic studies. (197851)
1977
30
Letter: Luteoma of pregnancy. (170823)
1975
31
Luteoma of pregnancy: report of a case and review of the literature. (163309)
1975
32
Remission of acanthosis nigricans associated with polycystic ovarian disease and a stromal luteoma. (4360917)
1974
33
Virilizing luteoma of pregnancy. Report of a case with measurements of testosterone and testosterone binding in plasma. (4346682)
1973
34
Gonadotropin receptor of a mouse luteoma: interactions with luteinizing hormone (LH) and its and subunits. (4351508)
1973
35
Luteoma in pregnancy. (4375468)
1973
36
Luteoma of pregnancy. (4335590)
1972
37
Transplantable luteoma of the mouse. An ultrastructural and biochemical study. (4338338)
1972
38
Luteoma of pregnancy. (4319381)
1970
39
Luteoma of pregnancy: recurrent or persistent? (5366428)
1969
40
Luteoma of pregnancy: steroidogenic and morphologic considerations. (4307340)
1969
41
Luteoma of pregnancy. Report of a case. (4317074)
1968
42
Ambiguous genitals in a female infant associated with luteoma of pregnancy. Report of a case. (4298215)
1968
43
Steroid content and synthesis in a virilizing luteoma. (4290318)
1967
44
Luteoma of pregnancy. A pseudotumor. (4193143)
1967
45
STROMAL LUTEOMA OF THE OVARY. A DISTINCTIVE TYPE OF LIPOID-CELL TUMOR. (14176990)
1964
46
PSEUDOPRECOCITY IN AN INFANT DUE TO A LUTEOMA OF THE OVARY. (14065997)
1963
47
Neutral steroids in the urine of a patient with a luteoma of the ovary. (13069593)
1953
48
Luteoma of the ovary. (14918776)
1952
49
Luteoma of the ovary; a case showing decidualization of the endometrium and a high pregnanediol excretion rate. (20984666)
1946
50
Transplantability of induced granulosa cell tumors and of luteoma in mice; secondary effects of these growths. (21024146)
1946

Variations for Luteoma

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Expression for genes affiliated with Luteoma

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Expression patterns in normal tissues for genes affiliated with Luteoma

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Pathways for genes affiliated with Luteoma

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Pathways related to Luteoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.0CGA, CYP21A2

Compounds for genes affiliated with Luteoma

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Compounds related to Luteoma according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1deoxyribonucleic acid449.6SRY, CYP21A2
2biotin44 24 1111.6SRY, CYP21A2
3agarose449.6CYP21A2, SRY
4nafarelin44 61 28 1112.4CGA, CYP21A2
517-hydroxypregnenolone449.4CGA, CYP21A2
611 deoxycortisol449.4CYP21A2, CGA
7leuprolide acetate449.4CGA, CYP21A2
8clomiphene citrate449.4CYP21A2, CGA
917-hydroxyprogesterone44 2410.4CGA, CYP21A2
103beta-hydroxysteroid449.4CGA, CYP21A2
1117beta-hydroxysteroid449.4CGA, CYP21A2
12dehydroepiandrosterone sulfate449.3CGA, CYP21A2
13phenytoin44 50 28 1112.3CYP21A2, CGA
14androstenedione44 2410.3CGA, CYP21A2
15thyroxine44 2410.3CGA, CYP21A2
16carbon449.3CGA, CYP21A2
17leucine449.2SRY, CYP21A2
18gnrh449.2CYP21A2, CGA
19epinephrine44 24 1111.2CGA, CYP21A2
20ribonucleic acid449.1CGA, CYP21A2
21norepinephrine44 24 1111.1CGA, CYP21A2
22forskolin44 50 1111.0CYP21A2, CGA
23progesterone44 28 61 24 1113.0CGA, CYP21A2
24dihydrotestosterone44 28 24 1111.9CGA, SRY, CYP21A2
25estradiol44 24 1110.9CGA, SRY, CYP21A2
26testosterone44 61 24 1111.9CGA, SRY, CYP21A2
27steroid448.8CYP21A2, SRY, CGA
28cycloheximide448.7CGA, CYP21A2
29serine448.7CGA, SRY, CYP21A2

GO Terms for genes affiliated with Luteoma

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Products for genes affiliated with Luteoma

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  • Antibodies
  • Proteins
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Sources for Luteoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet