Aliases & Classifications for Lymph Node Disease

Aliases & Descriptions for Lymph Node Disease:

Name: Lymph Node Disease 12 14
Disorder of Lymph Node 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9942
NCIt 47 C35346
SNOMED-CT 64 76616003
UMLS 69 C0272394

Summaries for Lymph Node Disease

MalaCards based summary : Lymph Node Disease, also known as disorder of lymph node, is related to persistent generalized lymphadenopathy and symmastia, and has symptoms including axillary lymph node pain, inguinal lymph node pain and inguinal lymph node tenderness. An important gene associated with Lymph Node Disease is MMP3 (Matrix Metallopeptidase 3), and among its related pathways/superpathways are Allograft rejection and T cell receptor signaling pathway. The drugs Dexamethasone and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include lymph node, liver and kidney, and related phenotypes are endocrine/exocrine gland and hematopoietic system

Wikipedia : 71 A lymph node or lymph gland, is an ovoid or kidney-shaped organ of the lymphatic system, and of the... more...

Related Diseases for Lymph Node Disease

Diseases related to Lymph Node Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)
id Related Disease Score Top Affiliating Genes
1 persistent generalized lymphadenopathy 10.8
2 symmastia 10.4 MMP1 MMP3
3 paraganglioma and gastric stromal sarcoma 10.3 SDHB SDHC SDHD
4 glioma susceptibility 2 10.3 SDHB SDHC SDHD
5 catastrophic antiphospholipid syndrome 10.3 SDHB SDHD TMEM127
6 serous surface papilloma 10.3 SDHB SDHC SDHD
7 acrocapitofemoral dysplasia 10.3 SDHB SDHD TMEM127
8 bone ameloblastoma 10.3 SDHB SDHD TMEM127
9 non-syndromic male infertility due to sperm motility disorder 10.2 SDHB SDHC SDHD
10 neurofibromatosis-noonan syndrome 10.2 SDHB SDHC SDHD
11 pasteurellosis 10.2 IL6 MMP1 MMP3
12 hypolipoproteinemia 10.2 CD40LG CRP MMP3
13 childhood teratocarcinoma of the testis 10.2 SDHB SDHC SDHD
14 germ cell and embryonal cancer 10.2 IL6 MMP1 MMP3
15 erythrocytosis, familial, 2 10.2 SDHB SDHC SDHD
16 coloboma of iris 10.1 CRP IL6
17 intravenous leiomyomatosis 10.1 SDHAF2 SDHB SDHC SDHD
18 endocervical adenocarcinoma 10.1 SDHAF2 SDHB SDHC SDHD
19 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.1 IL6 TNF
20 dermatomycosis 10.1 CD40LG CRP TNF
21 amaurosis congenita, cone-rod type, with congenital hypertrichosis 10.1 SDHA SDHB SDHC SDHD
22 cowden syndrome 3 10.1 SDHA SDHB SDHC SDHD
23 sarcoidosis 1 10.1
24 molybdenum cofactor deficiency a 10.1 CRP MMP1 MMP3 TNF
25 functional gastric disease 10.1 CD40LG CRP TNF
26 steatitis 10.1 CD8A TNF
27 acquired thrombocytopenia 10.1 IL6 MMP1 TNF
28 hereditary night blindness 10.1 IL6 MMP1 TNF
29 retinal degeneration 10.1 CD40LG CRP IL6
30 keratoconus 10.1 IL6 MMP3 TNF
31 autosomal recessive type iv ehlers-danlos syndrome 10.1 IL6 MMP1 TNF
32 orbital osteomyelitis 10.1 IL6 MMP3 TNF
33 gastrointestinal stromal tumor 10.1 SDHA SDHB SDHC SDHD
34 unilateral multicystic dysplastic kidney 10.1 CRP IL6 TNF
35 swine influenza 10.1 CRP IL6 TNF
36 prostate carcinoma in situ 10.1 CD4 CD40LG
37 joint disorders 10.1 CRP IL6 TNF
38 cicatricial lagophthalmos 10.0 CRP IL6 TNF
39 celiac disease 10.0 CD40LG CRP MMP3 TNF
40 stiff-person syndrome 10.0 CD40LG CRP IL6
41 benign neonatal seizures 10.0 CRP IL6 TNF
42 neuropathy 10.0 CRP IL6 TNF
43 autoimmune disease of central nervous system 10.0 CRP IL6 TNF
44 dextrocardia 10.0 CD40LG IL6 TNF
45 mild pre-eclampsia 10.0 CD40LG CD8A
46 conduct disorder 10.0 CD40LG IL6 TNF
47 endobronchial leiomyoma 10.0 CD40LG CRP TNF
48 pancreatic signet ring cell adenocarcinoma 10.0 CD40LG IL6 TNF
49 pancreas lymphoma 10.0 CRP IL6 TNF
50 childhood pleomorphic rhabdomyosarcoma 10.0 CD40LG IL6 TNF

Graphical network of the top 20 diseases related to Lymph Node Disease:



Diseases related to Lymph Node Disease

Symptoms & Phenotypes for Lymph Node Disease

UMLS symptoms related to Lymph Node Disease:


axillary lymph node pain, inguinal lymph node pain, inguinal lymph node tenderness

MGI Mouse Phenotypes related to Lymph Node Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.96 CD8A EPCAM IL6 ITPKC MMP14 SDHB
2 hematopoietic system MP:0005397 9.85 MMP3 TNF CD4 CD40LG CD8A EPCAM
3 homeostasis/metabolism MP:0005376 9.73 CD4 CD40LG CRP EPCAM IL6 MMP1
4 immune system MP:0005387 9.4 CD4 CD40LG CD8A CRP EPCAM IL6

Drugs & Therapeutics for Lymph Node Disease

Drugs for Lymph Node Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 584)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
2
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
3
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
4
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
5
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
6
Carboplatin Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 41575-94-4 10339178 498142 38904
7
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
8
Iron Approved Phase 4,Phase 3,Phase 1,Phase 2 7439-89-6 23925
9
Azithromycin Approved Phase 4 83905-01-5 55185 53477736 447043
10
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
11
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
12
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 124-94-7 31307
13
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
14
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1 51-21-8 3385
15
Epirubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 56420-45-2 41867
16
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 1 53-03-2 5865
17
Technetium tc 99m sulfur colloid Approved Phase 4,Phase 2
18
Vinblastine Approved Phase 4,Phase 3,Phase 2 865-21-4 13342 241903
19
Indinavir Approved Phase 4,Phase 1 150378-17-9 5362440
20
Irinotecan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 97682-44-5, 100286-90-6 60838
21
Gemcitabine Approved Phase 4,Phase 3,Phase 2,Phase 1 95058-81-4 60750
22
Zidovudine Approved Phase 4,Phase 2,Phase 1 30516-87-1 35370
23
Lamivudine Approved, Investigational Phase 4,Phase 2,Phase 1 134678-17-4 60825
24
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
25
Vancomycin Approved Phase 4 1404-90-6 441141 14969
26
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
27
Certolizumab pegol Approved Phase 4 428863-50-7
28
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
29
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
30
Edetic Acid Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 60-00-4, 62-33-9 6049
31
Somatostatin Approved Phase 4,Phase 3 38916-34-6, 51110-01-1 53481605
32
Levoleucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1 68538-85-2
33
Ganciclovir Approved, Investigational Phase 4,Phase 2 82410-32-0 3454
34
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
35
Valganciclovir Approved, Investigational Phase 4,Phase 2 175865-60-8 64147
36
Ribavirin Approved Phase 4 36791-04-5 37542
37
Sofosbuvir Approved Phase 4 1190307-88-0 45375808
38
Ledipasvir Approved Phase 4 1256388-51-8 67505836
39
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-05-9 54575, 6560146 143
40
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 59-30-3 6037
41
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 11103-57-4, 68-26-8 445354
42
Docetaxel Approved May 1996, Investigational Phase 4,Phase 3,Phase 2,Phase 1 114977-28-5 148124 9877265
43
Methylene blue Investigational Phase 4,Phase 3,Phase 2 61-73-4
44
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1 31703
45
Camptothecin Experimental Phase 4,Phase 2,Phase 1 7689-03-4
46 triamcinolone acetonide Phase 4,Phase 3,Phase 1,Phase 2
47 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1 1177-87-3
48 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
49 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1
50 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 1695)
id Name Status NCT ID Phase
1 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4
2 Pre-Operative Staging of Pancreatic Cancer Using Superparamagnetic Iron Oxide Magnetic Resonance Imaging (SPIO MRI) Unknown status NCT00920023 Phase 4
3 Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion Unknown status NCT00313066 Phase 4
4 Endoesophageal Cryotherapy For Ablating Barrett's Esophagus and Early Stage Esophageal Cancer Unknown status NCT00628784 Phase 4
5 MR-Lymphography and Lymph Node Staging in Prostate Cancer Unknown status NCT00185029 Phase 4
6 Prevention of Neutropenia After Using G-CSF With TAC Chemotherapy Unknown status NCT01571518 Phase 4
7 Clinical Trial Comparing Outcomes of Breast Conserving Operations With Classic v High-frequency Electrocoagulation Unknown status NCT01216254 Phase 4
8 Study of Combined Therapy of Aspirin and "IVIG-SN" in Kawasaki Disease Completed NCT01524939 Phase 4
9 Conventional Versus Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Hilar/Mediastinal Lymphadenopathies Completed NCT01658280 Phase 4
10 RCT: Difference in Diagnostic Yield Between EUSFNA Needles With and Without a Side Port in Pancreatic Masses Completed NCT02092519 Phase 4
11 Clinical and Economic Outcomes of Ceftaroline Fosamil for ABSSSI Documented or at Risk of MRSA Completed NCT02582203 Phase 4
12 Post-Operative Drainage Following Lymph Node Dissection Completed NCT00324272 Phase 4
13 Sentinel Lymph Node Mapping Post-Injection Site Pain Completed NCT02065232 Phase 4
14 A Study for Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Radical Lymph Node Dissection Completed NCT02476357 Phase 4
15 Application of Somatostatin for Advanced Gastric Cancer After D2 Lymph Node Dissection Completed NCT01914692 Phase 4
16 Wound Infiltration and Breast Cancer Surgery Completed NCT01404377 Phase 4
17 An Open-label, Multi-center Phase Ⅳ Trial to Evaluate the Efficacy and Safety of Sequential Neoadjuvant Chemotherapy With Docetaxel(Monotaxel®) After Doxorubicin Plus Cyclophosphamide Combination Chemotherapy in Locally Advanced Breast Cancer Completed NCT01660542 Phase 4
18 Certolizumab and Lower Extremity Lymph Flow in Rheumatoid Arthritis (RA) Completed NCT01098201 Phase 4
19 The Effectiveness of Indinavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients With No Symptoms of Infection Completed NCT00002179 Phase 4
20 Cervicovaginal Immune Responses to 3 Deltoid or Thigh Intramuscular (IM) TicoVac Completed NCT01710189 Phase 4
21 Phase IV Trial to Evaluate Breast Brachytherapy Using the Mammosite-Ml® Completed NCT01448447 Phase 4
22 Study the Use of Magseed and Sentimag to Localize Axillary Lymph Nodes Recruiting NCT03038152 Phase 4
23 A Multi-center, Randomized to Compare the Efficacy of IVIG Alone and IVIG Plus High-dose Aspirin in Kawasaki Disease Recruiting NCT02951234 Phase 4
24 Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer Recruiting NCT02366819 Phase 4
25 Surgery Alone, Surgery With Cyclophosphamide, Vinblastine, and Prednisolone (CVP), or CVP Alone in Treating Young Patients With Stage IA or Stage IIA Nodular Lymphocyte-Predominant Hodgkin Lymphoma Recruiting NCT01088750 Phase 4
26 The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor Recruiting NCT03017053 Phase 4
27 Selective Lymph Node Dissection Using Fluorescent Dye in Node-positive Breast Cancer Recruiting NCT02781259 Phase 4
28 Methylene Blue Intradermal Injection for Sentinel Lymph Node Biopsy for Breast Cancer Patients Recruiting NCT02982148 Phase 4
29 Epirubicin Versus Docetaxel Plus Cyclophosphamide in Lymph Node Negative, ER-positive, Her2-negative Breast Cancer Recruiting NCT02549677 Phase 4
30 Lymphedema Following Hand/Wrist Surgery in Women Post Axillary Node Dissection Recruiting NCT00984269 Phase 4
31 Effect of TachoSil® on Incidence of Symptomatic and Radiographic Lymphoceles After Extended Pelvic Lymph Node Dissection in Prostate and Bladder Cancer. Recruiting NCT02001857 Phase 4
32 Randomised Trial of LightPath Imaging in Breast Cancer Surgery Recruiting NCT02666079 Phase 4
33 Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci Recruiting NCT02712307 Phase 4
34 Immunity to Hepatitis B Vaccine Recruiting NCT03083158 Phase 4
35 Oral Hepatitis C Treatment for Indolent Lymphoma (OPTImaL) Study Active, not recruiting NCT02717949 Phase 4
36 Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study Active, not recruiting NCT02542462 Phase 4
37 Sentinel Lymph Node Biopsy Findings in Patients With Breast Cancer Active, not recruiting NCT02287675 Phase 4
38 Sienna+® Injection Time Study 4 Arms Not yet recruiting NCT02612870 Phase 4
39 Complete Mesocolon Excision vs Locoregional Lymphadenectomy in Sigmoid Colon Cancer (CMELL) Not yet recruiting NCT03083951 Phase 4
40 Lipusu Advanced Squamous Cell Carcinoma of Lung Study Carboplatin in Advanced Squamous Cell Carcinoma of Lung Not yet recruiting NCT02996214 Phase 4
41 GeneSearch Breast Lymph Node (BLN) Assay Timing Study Terminated NCT00595023 Phase 4
42 Valganciclovir to Treat HHV-8 Associated Multicentric Castleman's Disease Withdrawn NCT00361933 Phase 4
43 Magnetic Resonance Imaging for Lymph Node Staging in Ovarian Cancer Withdrawn NCT02243059 Phase 4
44 Study of Exemestane After Anastrozole or Letrozole Treatment of Postmenopausal Women With Hormone Responsive Breast Cancer Unknown status NCT00902954 Phase 3
45 Usefulness of FDG-PET for Advanced Cervical Cancer Unknown status NCT00146458 Phase 3
46 Docetaxel Based Anthracycline Free Adjuvant Treatment Evaluation, as Well as Life Style Intervention Unknown status NCT00847444 Phase 3
47 PET/CT Scan-Guided Watchful Waiting or Neck Dissection of Locally Advanced Lymph Node Metastases in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Primary Head And Neck Cancer Unknown status NCT00720070 Phase 3
48 A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment. Unknown status NCT01941979 Phase 3
49 Digital Mammography, Ultrasound, MRI, and PET Scans in Women With Newly Diagnosed Breast Cancer Unknown status NCT00194337 Phase 2, Phase 3
50 A Multicenter Clinical Trial on Laparoscopic Gastric Cancer Surgery Compared With Open Surgery Unknown status NCT02302794 Phase 3

Search NIH Clinical Center for Lymph Node Disease

Genetic Tests for Lymph Node Disease

Anatomical Context for Lymph Node Disease

MalaCards organs/tissues related to Lymph Node Disease:

39
Lymph Node, Liver, Kidney, Lung, Breast, Thyroid

Publications for Lymph Node Disease

Articles related to Lymph Node Disease:

(show all 22)
id Title Authors Year
1
Axillary Ultrasound Accurately Excludes Clinically Significant Lymph Node Disease in Patients With Early Stage Breast Cancer. ( 26779976 )
2016
2
Unexpected lymph node disease in resections for pulmonary metastases. ( 25440271 )
2015
3
Is Minimal Residual Lymph Node Disease in Papillary Thyroid Cancer of Prognostic Impact? An Analysis of The Epithelial Cell Adhesion Molecule EpCAM in Lymph Nodes of 40 pN0 Patients. ( 23918549 )
2014
4
Critical analysis of the 2010 TNM classification in patients with lymph node-positive bladder cancer: influence of lymph node disease burden. ( 25027685 )
2014
5
The prognosis of N2b and N2c lymph node disease in oral squamous cell carcinoma is determined by the number of metastatic lymph nodes rather than laterality: evidence to support a revision of the American Joint Committee on Cancer staging system. ( 24691658 )
2014
6
Clinical feasibility and diagnostic accuracy of detecting micrometastatic lymph node disease in sentinel and non-sentinel lyph nodes in cervical cancer: outcomes and implications. ( 24505957 )
2014
7
Residual lymph node disease after neoadjuvant chemotherapy predicts an increased risk of lymphedema in node-positive breast cancer patients. ( 23689935 )
2013
8
Imaging response and residual metastatic axillary lymph node disease after neoadjuvant chemotherapy for primary breast cancer. ( 23846781 )
2013
9
The impact of lymph node disease in extremity soft-tissue sarcomas: a population-based analysis. ( 23806824 )
2013
10
Survival of patients with non-small cell lung cancer according to lymph node disease: single pN1 vs multiple pN1 vs single unsuspected pN2. ( 23378017 )
2013
11
Subcutaneous emphysema as the first relevant clinical sign of complicated tubercular lymph node disease in a child. ( 24094042 )
2013
12
Prognostic significance of low volume sentinel lymph node disease in early-stage cervical cancer. ( 22120175 )
2012
13
Is Warthin's tumour of the parotid gland a lymph node disease? ( 21771031 )
2011
14
Prognostic significance and tumor biology of regional lymph node disease in patients with rhabdomyosarcoma: a report from the Children's Oncology Group. ( 21357792 )
2011
15
Minimal disease in the sentinel lymph node: how to best measure sentinel node micrometastases to predict risk of additional non-sentinel lymph node disease. ( 20532987 )
2010
16
Micrometastatic sentinel lymph node disease: do patients benefit or suffer harm from axillary lymph node dissection? ( 19937389 )
2010
17
Epithelial ovarian cancer relapsing as isolated lymph node disease: natural history and clinical outcome. ( 19077269 )
2008
18
Lymph node disease after radical prostatectomy. ( 17431370 )
2007
19
Is occult lymph node disease in colorectal cancer patients clinically significant? A review of the relevant literature. ( 17916603 )
2007
20
Prospective comparative study of integrated positron emission tomography-computed tomography scan compared with remediastinoscopy in the assessment of residual mediastinal lymph node disease after induction chemotherapy for mediastinoscopy-proven stage IIIA-N2 Non-small-cell lung cancer: a Leuven Lung Cancer Group Study. ( 16849747 )
2006
21
High-risk cutaneous squamous cell carcinoma of the head and neck: results from 266 treated patients with metastatic lymph node disease. ( 16649220 )
2006
22
Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma. ( 15912516 )
2005

Variations for Lymph Node Disease

Expression for Lymph Node Disease

Search GEO for disease gene expression data for Lymph Node Disease.

Pathways for Lymph Node Disease

Pathways related to Lymph Node Disease according to GeneCards Suite gene sharing:

(show all 22)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.74 CD4 CD40LG CD8A IL6 TNF
2
Show member pathways
12.3 CD4 CD40LG CD8A IL6 TNF
3
Show member pathways
12.23 IL6 MMP1 MMP3 TNF
4
Show member pathways
12.21 SDHA SDHB SDHC SDHD
5 12.09 IL6 MMP1 MMP14 TNF
6
Show member pathways
11.97 SDHA SDHB SDHC SDHD
7 11.91 CD4 CD8A IL6 TNF
8 11.88 IL6 MMP1 MMP3 TNF
9 11.81 IL6 MMP14 MMP3 TNF
10
Show member pathways
11.77 SDHA SDHB SDHC SDHD
11
Show member pathways
11.73 MMP1 MMP14 MMP3 TNF
12 11.69 CD4 CD8A IL6 TNF
13 11.62 IL6 MMP1 MMP3 TNF
14 11.55 MMP1 MMP14 MMP3
15 11.46 CD4 CD8A ITGAE TNF
16 11.43 CD40LG IL6 TNF
17 11.3 CD4 CD40LG CD8A
18 11.3 CD40LG IL6 ITGAE TNF
19 11.16 CD4 IL6 TNF
20
Show member pathways
11.15 CD40LG IL6 MMP1 MMP3 TNF
21 10.98 CD4 CD8A EPCAM IL6 ITGAE TNF
22 10.78 CRP IL6 TNF

GO Terms for Lymph Node Disease

Cellular components related to Lymph Node Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.65 CD4 CD40LG CD8A EPCAM TNF
2 external side of plasma membrane GO:0009897 9.43 CD4 CD40LG CD8A IL6 ITGAE TNF
3 respiratory chain complex II GO:0045273 9.16 SDHB SDHC
4 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 8.92 SDHA SDHB SDHC SDHD

Biological processes related to Lymph Node Disease according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.91 CD4 CD40LG CD8A IL6 TNF
2 extracellular matrix disassembly GO:0022617 9.67 MMP1 MMP14 MMP3
3 defense response to Gram-positive bacterium GO:0050830 9.65 CRP IL6 TNF
4 collagen catabolic process GO:0030574 9.61 MMP1 MMP14 MMP3
5 positive regulation of T cell proliferation GO:0042102 9.58 CD4 CD40LG IL6
6 positive regulation of protein oligomerization GO:0032461 9.52 MMP1 MMP3
7 T cell activation GO:0042110 9.5 CD4 CD8A IL6
8 succinate metabolic process GO:0006105 9.46 SDHA SDHB
9 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.37 IL6 TNF
10 negative regulation of lipid storage GO:0010888 9.33 CRP IL6 TNF
11 regulation of immunoglobulin secretion GO:0051023 9.26 CD40LG TNF
12 mitochondrial electron transport, succinate to ubiquinone GO:0006121 9.13 SDHA SDHAF2 SDHD
13 tricarboxylic acid cycle GO:0006099 9.02 SDHA SDHAF2 SDHB SDHC SDHD

Molecular functions related to Lymph Node Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 electron carrier activity GO:0009055 9.46 SDHA SDHB SDHC SDHD
2 ubiquinone binding GO:0048039 9.26 SDHB SDHD
3 succinate dehydrogenase (ubiquinone) activity GO:0008177 9.13 SDHA SDHB SDHD
4 succinate dehydrogenase activity GO:0000104 8.8 SDHA SDHC SDHD

Sources for Lymph Node Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....