MCID: LYM010
MIFTS: 39

Lymph Node Tuberculosis malady

Categories: Infectious diseases, Immune diseases

Aliases & Classifications for Lymph Node Tuberculosis

Aliases & Descriptions for Lymph Node Tuberculosis:

Name: Lymph Node Tuberculosis 12 14 69
King's Evil 12 42 69
Scrofula 12 69
Tuberculous Lymphadenopathy 12
Tuberculosis, Lymph Node 42
Tuberculous Adenitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4889
ICD10 33 A18.2
NCIt 47 C26896
SNOMED-CT 64 10893003 186260002

Summaries for Lymph Node Tuberculosis

Disease Ontology : 12 An extrapulmonary tuberculosis that is located in lymph node, and has symptom lymphadenopathy, has symptom fever, has symptom weight loss, has symptom fatigue, has symptom night sweats and has symptom cough.

MalaCards based summary : Lymph Node Tuberculosis, also known as king's evil, is related to tuberculosis and cervicitis, and has symptoms including lymphadenopathy, fever and weight loss. An important gene associated with Lymph Node Tuberculosis is SP110 (SP110 Nuclear Body Protein). The drugs Anti-Infective Agents and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include lymph node, breast and lung, and related phenotypes are craniofacial and respiratory system

Related Diseases for Lymph Node Tuberculosis

Diseases related to Lymph Node Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 29)
id Related Disease Score Top Affiliating Genes
1 tuberculosis 10.6
2 cervicitis 10.0
3 mucoepidermoid thyroid carcinoma 10.0 FEZF1 FEZF2
4 iritis 10.0 FEZF1 FEZF2
5 mediastinitis 10.0
6 hepatic angiomyolipoma 10.0 FEZF1 FEZF2
7 ascending colon cancer 9.9 FEZF1 FEZF2
8 pulmonary tuberculosis 9.9
9 eosinophilia-myalgia syndrome 9.9 FEZF1 FEZF2
10 goiter 9.7
11 cholestasis 9.7
12 rheumatoid arthritis 9.7
13 breast cancer 9.7
14 arthritis 9.7
15 thrombocytopenia 9.7
16 lymphoma 9.7
17 osteomyelitis 9.7
18 tonsillitis 9.7
19 cat-scratch disease 9.7
20 obstructive jaundice 9.7
21 interstitial lung disease 9.7
22 purpura 9.7
23 pancreatitis 9.7
24 pneumonia 9.7
25 inflammatory breast carcinoma 9.7
26 lung disease 9.7
27 miliary tuberculosis 9.7
28 leukemia 9.6
29 bile duct carcinoma 8.9 EPC2 FBLN5 FEZF1 FEZF2 PTBP2 SP110

Graphical network of the top 20 diseases related to Lymph Node Tuberculosis:



Diseases related to Lymph Node Tuberculosis

Symptoms & Phenotypes for Lymph Node Tuberculosis

Symptoms:

12
  • lymphadenopathy
  • fever
  • weight loss
  • fatigue
  • night sweats
  • cough

MGI Mouse Phenotypes related to Lymph Node Tuberculosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.26 FEZF2 THRA FBLN5 FEZF1
2 respiratory system MP:0005388 8.92 FBLN5 FEZF1 FEZF2 PTBP2

Drugs & Therapeutics for Lymph Node Tuberculosis

Drugs for Lymph Node Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Infective Agents Phase 3
2 Vaccines Phase 1, Phase 2
3
Ethanol Approved 64-17-5 702
4
Formaldehyde Approved, Vet_approved 50-00-0 712
5 Fluorides
6 Deoxyglucose
7 Fluorodeoxyglucose F18
8 Antimetabolites
9 Radiopharmaceuticals
10 Antiviral Agents
11 Disinfectants

Interventional clinical trials:

(show all 15)
id Name Status NCT ID Phase
1 Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion Unknown status NCT00313066 Phase 4
2 Comparison of Antibiotic Therapy Alone or Combined With Corticosteroids for the Treatment of Nontuberculous Mycobacterial Cervicofacial Lymphadenitis in Children: A Randomized Double-Blind Placebo-Controlled Study Withdrawn NCT01614977 Phase 3
3 Vaccine Treatment for Advanced Non-Small Cell Lung Cancer Completed NCT00073398 Phase 1, Phase 2
4 VRC 307: A Double-Blind, Randomized Phase I Study of the Safety and Immunogenicity of a Prime-Boost Schedule of the Investigational DNA Trivalent Influenza Vaccine, VRC-FLUDNA047-00-VP, Followed by the 2008/2009 Seasonal Influenza Trivalent Inactivat... Completed NCT00858611 Phase 1
5 Diagnosis of Mediastinal Tuberculous Lymphadenopathy by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) Unknown status NCT01121432
6 Bronchoscopic Sampling Techniques in Sarcoidosis Unknown status NCT01836822
7 Positron Emission Tomography in Extrapulmonary Tuberculosis Completed NCT01613196
8 Endobronchial Ultrasound Guided Transbronchial Aspiration (EBUS-TBNA) in Non Small Cell Lung Cancer (NSCLC) in a Tuberculosis-endemic Country Completed NCT01156623
9 Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon) Completed NCT01331811
10 Role of EBUS-TBNA in Diagnosing TB in Mediastinal/Hilar Lymph Nodes Recruiting NCT01350674
11 Diagnostic Accuracy of Polymerase Chain Reaction for Mycobacterium Tuberculosis Using EBUS-TBNA Samples Recruiting NCT02497079
12 PET Imaging and Lymph Node Assessment of IRIS in People With AIDS Recruiting NCT02147405
13 Immune Reconstitution Syndrome in HIV-Infected Patients Taking Antiretroviral Therapy Active, not recruiting NCT00286767
14 Molecular and Clinical Studies of Primary Immunodeficiency Diseases Enrolling by invitation NCT00006319
15 Evolution of Indications for Transbronchial Ganglionic Ultrasound in the Picardie Region Over the Period 2008 - 2013 Not yet recruiting NCT03132883

Search NIH Clinical Center for Lymph Node Tuberculosis

Cochrane evidence based reviews: king's evil

Genetic Tests for Lymph Node Tuberculosis

Anatomical Context for Lymph Node Tuberculosis

MalaCards organs/tissues related to Lymph Node Tuberculosis:

39
Lymph Node, Breast, Lung, T Cells, Testes, Tonsil, Adrenal Cortex

The Foundational Model of Anatomy Ontology organs/tissues related to Lymph Node Tuberculosis:

18
Lymph Node

Publications for Lymph Node Tuberculosis

Articles related to Lymph Node Tuberculosis:

(show top 50) (show all 85)
id Title Authors Year
1
Paradoxical reaction associated with cervical lymph node tuberculosis: predictive factors and therapeutic management. ( 27810522 )
2017
2
Diagnostic performance of interferon-I^ release assay for lymph node tuberculosis. ( 26971638 )
2016
3
Add-on prednisolone in the management of cervical lymph node tuberculosis. ( 27451818 )
2016
4
A Case Report: Systemic Lymph Node Tuberculosis Mimicking Lymphoma on 18F-FDG PET/CT. ( 26945389 )
2016
5
Lymph node tuberculosis after allogeneic haematopoietic stem cell transplantation: an atypical presentation of an uncommon complication. ( 26015804 )
2015
6
MICROSCOPIC-OBSERVATION DRUG-SUSCEPTIBILITY (MODS) FOR RAPID DIAGNOSIS OF LYMPH NODE TUBERCULOSIS AND DETECTION OF DRUG RESISTANCE. ( 26511739 )
2015
7
Delayed diagnosis of lymph node tuberculosis: time-honored importance of a thorough clinical examination, Cameroon. ( 26405474 )
2015
8
Axillary lymph node tuberculosis masquerading as inflammatory breast carcinoma in an immune-compromised patient. ( 25681261 )
2015
9
Epidemiology of Peripheral Lymph Node Tuberculosis and Genotyping of M. tuberculosis Strains: A Case-Control Study. ( 26177546 )
2015
10
Diagnosis of lymph node tuberculosis using the GeneXpert MTB/RIF in Tunisia. ( 26964807 )
2015
11
Immune thrombocytopenia (ITP): a rare association of lymph node tuberculosis. ( 25327103 )
2014
12
Progenitor a89Mycobacterium canettiia89 clone responsible for lymph node tuberculosis epidemic, Djibouti. ( 24520560 )
2014
13
A late presentation of isolated lymph node tuberculosis postintravesical BCG therapy for superficial bladder cancer: a novel case. ( 24792024 )
2014
14
Lymph node tuberculosis - an attempt of clinico-morphological study and review of the literature. ( 25178325 )
2014
15
Progenitor "Mycobacterium canettii" Clone Responsible for Lymph Node Tuberculosis Epidemic, Djibouti. ( 24378119 )
2014
16
Cat scratch disease and lymph node tuberculosis in a colon patient with cancer. ( 24334464 )
2013
17
Diagnostic accuracy and effectiveness of the Xpert MTB/RIF assay for the diagnosis of HIV-associated lymph node tuberculosis. ( 23660698 )
2013
18
Systemic lymph node tuberculosis presenting with an aseptic psoas abscess caused by a paradoxical reaction after nine months of antituberculosis treatment: a case report. ( 23497500 )
2013
19
[Obstructive jaundice secondary to liver hilar lymph node tuberculosis]. ( 22817998 )
2013
20
Interstitial lung disease and profound hypoxaemia in a severely-malnourished child with very severe pneumonia and potential lymph-node tuberculosis: an uncommon but serious co-morbidity. ( 23617214 )
2013
21
Diagnostic usefulness of a T-cell-based assay in patients with miliary tuberculosis compared with those with lymph node tuberculosis. ( 23051762 )
2013
22
Pancreatic head region lymph node tuberculosis mimicking pancreatic solid pseudopapillary tumor. ( 23489813 )
2013
23
Risk factors for prolonged treatment of lymph node tuberculosis. ( 22230257 )
2012
24
Isolated axillary lymph node tuberculosis in ultrasonography. A case report. ( 26674808 )
2012
25
Sweet's syndrome in a patient with rheumatoid arthritis, SjAPgren's syndrome and lymph node tuberculosis. ( 22714601 )
2011
26
Genetic association study suggests a role for SP110 variants in lymph node tuberculosis but not pulmonary tuberculosis in north Indians. ( 21536091 )
2011
27
Management of peripheral lymph node tuberculosis in routine practice: an unselected 10-year cohort. ( 21333106 )
2011
28
Assessment of lymph node tuberculosis in two provinces in Turkey. ( 21788708 )
2011
29
Treatment for lymph node tuberculosis. ( 20219818 )
2010
30
Post-therapy paradoxical response in immunocompetent patients with lymph node tuberculosis. ( 20831881 )
2010
31
Epidemiological, therapeutic and evolutionary profiles in patients with lymph node tuberculosis. ( 21341113 )
2010
32
Lymph node tuberculosis in patients from regions with varying burdens of tuberculosis and human immunodeficiency virus (HIV) infection. ( 20646895 )
2010
33
Lymph node tuberculosis and paradoxical evolution. ( 20122063 )
2010
34
Lymph node tuberculosis. Time for a culture change? ( 20388678 )
2010
35
Paradoxical responses in non-HIV-infected patients with peripheral lymph node tuberculosis. ( 19535147 )
2009
36
CA-125: a marker for diagnosis and follow-up of pleuroperitoneal and lymph node tuberculosis. ( 18398279 )
2008
37
Intraparotid lymph node tuberculosis. ( 18500020 )
2008
38
Severe paradoxical reaction requiring tracheostomy in a human immunodeficiency virus (HIV)-negative patient with cervical lymph node tuberculosis. ( 18972608 )
2008
39
A low molecular weight ES-20 protein released in vivo and in vitro with diagnostic potential in lymph node tuberculosis. ( 18227594 )
2008
40
Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64. ( 17894882 )
2007
41
Study of M. tuberculosis ES-31 and ES-20 antigen levels in different pathogenic grades of lymph node tuberculosis. ( 17263295 )
2007
42
Tonsillar and lymph node tuberculosis revealing asymptomatic pulmonary tuberculosis. ( 18037681 )
2007
43
Isolated cystic duct lymph node tuberculosis. ( 18236910 )
2007
44
Supraclavicular lymph node tuberculosis presenting with immune thrombocytopenic purpura. ( 17935681 )
2007
45
A boy undergoing maintenance hemodialysis who developed mediastinal lymph node tuberculosis. ( 16791404 )
2006
46
Clinical evaluation of a 16S ribosomal RNA polymerase chain reaction test for the diagnosis of lymph node tuberculosis. ( 16941366 )
2006
47
Persistent mediastinal and axillary lymph node tuberculosis in a renal transplant patient with successful outcome. ( 16797296 )
2006
48
Treatment of lymph node tuberculosis--a randomized clinical trial of two 6-month regimens. ( 16262733 )
2005
49
Subungual erythema in lymph node tuberculosis with erythema nodosum. ( 16459538 )
2005
50
Systemic steroid treatment of paradoxical upgrading reaction in patients with lymph node tuberculosis. ( 16107998 )
2005

Variations for Lymph Node Tuberculosis

Expression for Lymph Node Tuberculosis

Search GEO for disease gene expression data for Lymph Node Tuberculosis.

Pathways for Lymph Node Tuberculosis

GO Terms for Lymph Node Tuberculosis

Biological processes related to Lymph Node Tuberculosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.77 EPC2 FEZF1 FEZF2 SP110 THRA
2 transcription, DNA-templated GO:0006351 9.65 EPC2 FEZF1 FEZF2 SP110 THRA
3 positive regulation of neuron differentiation GO:0045666 9.32 FEZF1 FEZF2
4 forebrain development GO:0030900 9.16 FEZF1 FEZF2
5 telencephalon development GO:0021537 8.96 FEZF1 FEZF2
6 forebrain anterior/posterior pattern specification GO:0021797 8.62 FEZF1 FEZF2

Sources for Lymph Node Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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