MCID: LYM010
MIFTS: 34

Lymph Node Tuberculosis

Categories: Infectious diseases, Immune diseases

Aliases & Classifications for Lymph Node Tuberculosis

MalaCards integrated aliases for Lymph Node Tuberculosis:

Name: Lymph Node Tuberculosis 12 14 69
King's Evil 12 42 69
Scrofula 12 69
Tuberculous Lymphadenopathy 12
Tuberculosis, Lymph Node 42
Tuberculous Adenitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4889
ICD10 33 A18.2
NCIt 47 C26896
SNOMED-CT 64 10893003 186260002

Summaries for Lymph Node Tuberculosis

Disease Ontology : 12 An extrapulmonary tuberculosis that is located in lymph node, and has symptom lymphadenopathy, has symptom fever, has symptom weight loss, has symptom fatigue, has symptom night sweats and has symptom cough.

MalaCards based summary : Lymph Node Tuberculosis, also known as king's evil, is related to tuberculosis and cervicitis. An important gene associated with Lymph Node Tuberculosis is SP110 (SP110 Nuclear Body Protein). The drugs Anti-Infective Agents and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include lymph node, lung and breast, and related phenotypes are cellular and craniofacial

Related Diseases for Lymph Node Tuberculosis

Diseases related to Lymph Node Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 27)
id Related Disease Score Top Affiliating Genes
1 tuberculosis 10.7
2 cervicitis 10.0
3 mediastinitis 10.0
4 pulmonary tuberculosis 9.9
5 pancreatitis 9.8
6 iritis 9.8 FEZF1 FEZF2
7 ascending colon cancer 9.7 FEZF1 FEZF2
8 lacrimal gland mucoepidermoid carcinoma 9.7 FEZF1 FEZF2
9 rheumatoid arthritis 9.7
10 breast cancer 9.7
11 arthritis 9.7
12 thrombocytopenia 9.7
13 lymphoma 9.7
14 osteomyelitis 9.7
15 tonsillitis 9.7
16 cat-scratch disease 9.7
17 obstructive jaundice 9.7
18 melanoma 9.7
19 interstitial lung disease 9.7
20 purpura 9.7
21 pneumonia 9.7
22 inflammatory breast carcinoma 9.7
23 lung disease 9.7
24 miliary tuberculosis 9.7
25 substance dependence 9.6 FEZF1 FEZF2
26 angiomyolipoma 9.4 FEZF1 FEZF2
27 rete ovarii adenocarcinoma 7.2 EPC2 FBLN5 FEZF1 FEZF2 PTBP2 SP110

Graphical network of the top 20 diseases related to Lymph Node Tuberculosis:



Diseases related to Lymph Node Tuberculosis

Symptoms & Phenotypes for Lymph Node Tuberculosis

MGI Mouse Phenotypes related to Lymph Node Tuberculosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.65 FBLN5 FEZF1 FEZF2 PTBP2 THRA
2 craniofacial MP:0005382 9.46 FBLN5 FEZF1 FEZF2 THRA
3 respiratory system MP:0005388 9.26 FBLN5 FEZF1 FEZF2 PTBP2
4 taste/olfaction MP:0005394 8.62 FEZF1 FEZF2

Drugs & Therapeutics for Lymph Node Tuberculosis

Drugs for Lymph Node Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Infective Agents Phase 3
2 Vaccines Phase 1
3
Ethanol Approved 64-17-5 702
4
Formaldehyde Approved, Vet_approved 50-00-0 712
5 Antimetabolites
6 Antiviral Agents
7 Deoxyglucose
8 Fluorodeoxyglucose F18
9 Fluorides
10 Radiopharmaceuticals
11 Disinfectants

Interventional clinical trials:

(show all 13)

id Name Status NCT ID Phase Drugs
1 Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion Unknown status NCT00313066 Phase 4
2 Comparison of Antibiotic Therapy Alone or Combined With Corticosteroids for the Treatment of Nontuberculous Mycobacterial Cervicofacial Lymphadenitis in Children: A Randomized Double-Blind Placebo-Controlled Study Withdrawn NCT01614977 Phase 3 Methylprednisoline
3 VRC 307: A Double-Blind, Randomized Phase I Study of the Safety and Immunogenicity of a Prime-Boost Schedule of the Investigational DNA Trivalent Influenza Vaccine, VRC-FLUDNA047-00-VP, Followed by the 2008/2009 Seasonal Influenza Trivalent Inactivat... Completed NCT00858611 Phase 1 VRC-FLUDNA047-00-VP;Flulaval (Registered) Seasonal Influenza Vaccine
4 Diagnosis of Mediastinal Tuberculous Lymphadenopathy by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) Unknown status NCT01121432
5 Bronchoscopic Sampling Techniques in Sarcoidosis Unknown status NCT01836822
6 Positron Emission Tomography in Extrapulmonary Tuberculosis Completed NCT01613196
7 Endobronchial Ultrasound Guided Transbronchial Aspiration (EBUS-TBNA) in Non Small Cell Lung Cancer (NSCLC) in a Tuberculosis-endemic Country Completed NCT01156623
8 Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon) Completed NCT01331811
9 Diagnostic Accuracy of Polymerase Chain Reaction for Mycobacterium Tuberculosis Using EBUS-TBNA Samples Recruiting NCT02497079
10 PET Imaging and Lymph Node Assessment of IRIS in People With AIDS Recruiting NCT02147405
11 Immune Reconstitution Syndrome in HIV-Infected Patients Taking Antiretroviral Therapy Active, not recruiting NCT00286767
12 Evolution of Indications for Transbronchial Ganglionic Ultrasound in the Picardie Region Over the Period 2008 - 2013 Not yet recruiting NCT03132883
13 Role of EBUS-TBNA in Diagnosing TB in Mediastinal/Hilar Lymph Nodes Suspended NCT01350674

Search NIH Clinical Center for Lymph Node Tuberculosis

Cochrane evidence based reviews: king's evil

Genetic Tests for Lymph Node Tuberculosis

Anatomical Context for Lymph Node Tuberculosis

MalaCards organs/tissues related to Lymph Node Tuberculosis:

39
Lymph Node, Lung, Breast, T Cells, Adrenal Cortex, Tonsil, Testes

Publications for Lymph Node Tuberculosis

Articles related to Lymph Node Tuberculosis:

(show top 50) (show all 90)
id Title Authors Year
1
Clinical usefulness of (18)F-FDG PET/CT for initial staging and assessment of treatment efficacy in patients with lymph node tuberculosis. ( 28426991 )
2017
2
Lymph node tuberculosis mimicking malignancy on (18)F-FDG PET/CT in two patients: A case report. ( 28587415 )
2017
3
Paradoxical reaction associated with cervical lymph node tuberculosis: predictive factors and therapeutic management. ( 27810522 )
2017
4
Primary peripancreatic lymph node tuberculosis as a differential diagnosis of pancreatic neoplasia. ( 28506074 )
2017
5
Spontaneous chylothorax revealing a mediastinal and abdominal lymph node tuberculosis. ( 28410698 )
2017
6
A Case Report: Systemic Lymph Node Tuberculosis Mimicking Lymphoma on 18F-FDG PET/CT. ( 26945389 )
2016
7
Lymph node tuberculosis after melanoma treatment - sometimes the patient is lucky. ( 28174808 )
2016
8
Add-on prednisolone in the management of cervical lymph node tuberculosis. ( 27451818 )
2016
9
Diagnostic performance of interferon-I^ release assay for lymph node tuberculosis. ( 26971638 )
2016
10
Epidemiology of Peripheral Lymph Node Tuberculosis and Genotyping of M. tuberculosis Strains: A Case-Control Study. ( 26177546 )
2015
11
Axillary lymph node tuberculosis masquerading as inflammatory breast carcinoma in an immune-compromised patient. ( 25681261 )
2015
12
Delayed diagnosis of lymph node tuberculosis: time-honored importance of a thorough clinical examination, Cameroon. ( 26405474 )
2015
13
Lymph node tuberculosis after allogeneic haematopoietic stem cell transplantation: an atypical presentation of an uncommon complication. ( 26015804 )
2015
14
MICROSCOPIC-OBSERVATION DRUG-SUSCEPTIBILITY (MODS) FOR RAPID DIAGNOSIS OF LYMPH NODE TUBERCULOSIS AND DETECTION OF DRUG RESISTANCE. ( 26511739 )
2015
15
Diagnosis of lymph node tuberculosis using the GeneXpert MTB/RIF in Tunisia. ( 26964807 )
2015
16
A late presentation of isolated lymph node tuberculosis postintravesical BCG therapy for superficial bladder cancer: a novel case. ( 24792024 )
2014
17
Progenitor "Mycobacterium canettii" Clone Responsible for Lymph Node Tuberculosis Epidemic, Djibouti. ( 24378119 )
2014
18
Lymph node tuberculosis - an attempt of clinico-morphological study and review of the literature. ( 25178325 )
2014
19
Progenitor a89Mycobacterium canettiia89 clone responsible for lymph node tuberculosis epidemic, Djibouti. ( 24520560 )
2014
20
Immune thrombocytopenia (ITP): a rare association of lymph node tuberculosis. ( 25327103 )
2014
21
[Obstructive jaundice secondary to liver hilar lymph node tuberculosis]. ( 22817998 )
2013
22
Diagnostic accuracy and effectiveness of the Xpert MTB/RIF assay for the diagnosis of HIV-associated lymph node tuberculosis. ( 23660698 )
2013
23
Pancreatic head region lymph node tuberculosis mimicking pancreatic solid pseudopapillary tumor. ( 23489813 )
2013
24
Interstitial lung disease and profound hypoxaemia in a severely-malnourished child with very severe pneumonia and potential lymph-node tuberculosis: an uncommon but serious co-morbidity. ( 23617214 )
2013
25
Cat scratch disease and lymph node tuberculosis in a colon patient with cancer. ( 24334464 )
2013
26
Systemic lymph node tuberculosis presenting with an aseptic psoas abscess caused by a paradoxical reaction after nine months of antituberculosis treatment: a case report. ( 23497500 )
2013
27
Diagnostic usefulness of a T-cell-based assay in patients with miliary tuberculosis compared with those with lymph node tuberculosis. ( 23051762 )
2013
28
Isolated axillary lymph node tuberculosis in ultrasonography. A case report. ( 26674808 )
2012
29
Risk factors for prolonged treatment of lymph node tuberculosis. ( 22230257 )
2012
30
Genetic association study suggests a role for SP110 variants in lymph node tuberculosis but not pulmonary tuberculosis in north Indians. ( 21536091 )
2011
31
Assessment of lymph node tuberculosis in two provinces in Turkey. ( 21788708 )
2011
32
Sweet's syndrome in a patient with rheumatoid arthritis, SjAPgren's syndrome and lymph node tuberculosis. ( 22714601 )
2011
33
Management of peripheral lymph node tuberculosis in routine practice: an unselected 10-year cohort. ( 21333106 )
2011
34
Epidemiological, therapeutic and evolutionary profiles in patients with lymph node tuberculosis. ( 21341113 )
2010
35
Lymph node tuberculosis in patients from regions with varying burdens of tuberculosis and human immunodeficiency virus (HIV) infection. ( 20646895 )
2010
36
Lymph node tuberculosis and paradoxical evolution. ( 20122063 )
2010
37
Lymph node tuberculosis. Time for a culture change? ( 20388678 )
2010
38
Treatment for lymph node tuberculosis. ( 20219818 )
2010
39
Post-therapy paradoxical response in immunocompetent patients with lymph node tuberculosis. ( 20831881 )
2010
40
Paradoxical responses in non-HIV-infected patients with peripheral lymph node tuberculosis. ( 19535147 )
2009
41
Severe paradoxical reaction requiring tracheostomy in a human immunodeficiency virus (HIV)-negative patient with cervical lymph node tuberculosis. ( 18972608 )
2008
42
Intraparotid lymph node tuberculosis. ( 18500020 )
2008
43
CA-125: a marker for diagnosis and follow-up of pleuroperitoneal and lymph node tuberculosis. ( 18398279 )
2008
44
A low molecular weight ES-20 protein released in vivo and in vitro with diagnostic potential in lymph node tuberculosis. ( 18227594 )
2008
45
Isolated cystic duct lymph node tuberculosis. ( 18236910 )
2007
46
Study of M. tuberculosis ES-31 and ES-20 antigen levels in different pathogenic grades of lymph node tuberculosis. ( 17263295 )
2007
47
Tonsillar and lymph node tuberculosis revealing asymptomatic pulmonary tuberculosis. ( 18037681 )
2007
48
Supraclavicular lymph node tuberculosis presenting with immune thrombocytopenic purpura. ( 17935681 )
2007
49
Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64. ( 17894882 )
2007
50
A boy undergoing maintenance hemodialysis who developed mediastinal lymph node tuberculosis. ( 16791404 )
2006

Variations for Lymph Node Tuberculosis

Expression for Lymph Node Tuberculosis

Search GEO for disease gene expression data for Lymph Node Tuberculosis.

Pathways for Lymph Node Tuberculosis

GO Terms for Lymph Node Tuberculosis

Biological processes related to Lymph Node Tuberculosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.35 EPC2 FEZF1 FEZF2 SP110 THRA
2 transcription, DNA-templated GO:0006351 9.02 EPC2 FEZF1 FEZF2 SP110 THRA

Sources for Lymph Node Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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