MCID: LYM021
MIFTS: 47

Lymphadenitis malady

Skin diseases, Immune diseases categories

Summaries for Lymphadenitis

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66Wikipedia, 34MalaCards
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Wikipedia:66 Lymphadenopathy refers to lymph nodes which are abnormal in size, number or consistency and is often... more...

MalaCards: Lymphadenitis, also known as chronic lymphadenitis, is related to systemic lupus erythematosus and pulmonary tuberculosis. An important gene associated with Lymphadenitis is HSF4 (heat shock transcription factor 4), and among its related pathways are Leishmaniasis and Jak-STAT signaling pathway. The compound gp 130 have been mentioned in the context of this disorder. Affiliated tissues include lymph node, testes and breast, and related mouse phenotypes are immune system and hematopoietic system.

Aliases & Classifications for Lymphadenitis

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9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases, Immune diseases


Aliases & Descriptions:

lymphadenitis 9 11 63
chronic lymphadenitis 9 63
acute lymphadenitis 9 63
chronic lymphadenitis any lymph node, except mesenteric 9
inflammation of lymph node 9
lymphadenitis nos 9
chronic adenitis 9
acute adenitis 9
adenitis 9


Related Diseases for Lymphadenitis

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Lymphadenitis:



Diseases related to lymphadenitis

Symptoms for Lymphadenitis

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Drugs & Therapeutics for Lymphadenitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Lymphadenitis

Genetic Tests for Lymphadenitis

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Anatomical Context for Lymphadenitis

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34MalaCards
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MalaCards organs/tissues related to Lymphadenitis:

34
Lymph node, Testes, Breast, Skin, Thyroid, B cells, T cells, Lung, Tonsil, Whole blood, Eye, Prostate, Spleen, Liver, Myeloid, Salivary gland

Animal Models for Lymphadenitis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Lymphadenitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.0PDCD1, IL12RB1, IFNGR1, EBAG9
2MP:00053977.7PDCD1, IL12RB1, IFNGR1, EBAG9

Publications for Lymphadenitis

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53PubMed
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Articles related to Lymphadenitis:

(show top 50)    (show all 646)
idTitleAuthorsYear
1
Tuberculosis or tularemia? A molecular study in cervical lymphadenitis. (24239221)
2014
2
Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis. (24388082)
2014
3
Zygomycotic Mediastinal Lymphadenitis in Beef Cattle with Ruminal Tympany. (24018826)
2013
4
Kikuchi-Fujimoto lymphadenitis: role of parvovirus B-19, Epstein-Barr virus, human herpesvirus 6, and human herpesvirus 8. (22939574)
2013
5
Granulomatous lymphadenitis can also be seen in tularemia, not only in tuberculosis. (23219034)
2013
6
Tuberculous lymphadenitis in a dialysis patient diagnosed by 18-fluorodeoxyglucose positron emission tomography and IFN-I^ release assay. (24140370)
2013
7
Clinicopathological investigation on caseous lymphadenitis in local breed sheep in Algeria. (23604639)
2013
8
Treatment assessment based on computerized lymph node volume and ratio of necrotic area in tuberculous cervical lymphadenitis. (21872412)
2012
9
Management of lymphadenitis due to non-tuberculous mycobacterial infection in children. (22438045)
2012
10
Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease) after laparoscopic Roux-en-Y gastric bypass for morbid obesity: a case report. (23043774)
2012
11
Tuberculous cervical lymphadenitis masquerding as metastatis from papillary thyroid carcinoma. (23843822)
2012
12
Tuberculous lymphadenitis: FDG PET and CT findings in responsive and nonresponsive disease. (22526957)
2012
13
Kikuchi Fujimoto disease (histiocytic necrotizing lymphadenitis) following Hodgkin lymphoma. (22827768)
2012
14
Isolated porta hepatis lymphadenitis as a presenting feature of tuberculosis. (21841597)
2011
15
High sero-prevalence of caseous lymphadenitis identified in slaughterhouse samples as a consequence of deficiencies in sheep farm management in the state of Minas Gerais, Brazil. (22067701)
2011
16
Cervical tuberculous lymphadenitis. (21874804)
2011
17
Kikuchi's lymphadenitis. (19526580)
2010
18
Zygomycotic lymphadenitis in slaughtered feedlot cattle. (20080490)
2010
19
Lymphadenitis as a Rare Side Effect of H1N1 Vaccine in a Child. (21209734)
2010
20
Efficacy of an in-house polymerase chain reaction assay for rapid diagnosis of Mycobacterium tuberculosis in patients with tubercular lymphadenitis: comparison with fine needle aspiration cytology and conventional techniques. (21045399)
2010
21
Severe axillary lymphadenitis after BCG vaccination: alert for primary immunodeficiencies. (21195982)
2010
22
Cervical lymphadenitis due to Mycobacterium malmoense. (20417008)
2010
23
Identification and genotyping of the etiological agent of tuberculous lymphadenitis in Ethiopia. (19762953)
2009
24
Simultaneous peripheral tuberculous lymphadenitis and a tuberculous liver abscess in a hemodialysis patient. (19640372)
2009
25
Suppurative lymphadenitis. (19698282)
2009
26
Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease): lesional cells exhibit an immature dendritic cell phenotype. (19141377)
2009
27
Mycobacterial culture of fine needle aspirate - a useful tool in diagnosing tuberculous lymphadenitis. (18695328)
2008
28
Light-chain-restricted germinal centres in reactive lymphadenitis: report of eight cases. (18315596)
2008
29
A histopathological study of chronic granulomatous lymphadenitis. (17914532)
2007
30
Nontuberculous mycobacterial lymphadenitis in children. (17638208)
2007
31
Cervical lymphadenitis due to mycobacterium interjectum. (17352398)
2007
32
Six cases of suppurative lymphadenitis caused by Burkholderia pseudomallei infection. (16542691)
2006
33
Immunohistochemistry using a Mycobacterium tuberculosis complex specific antibody for improved diagnosis of tuberculous lymphadenitis. (16980944)
2006
34
A serological investigation of caseous lymphadenitis in four flocks of sheep. (21851675)
2006
35
Deep neck infection complicating lymphadenitis caused by Streptococcus intermedius in an immunocompetent child. (16553945)
2006
36
Detailed nodal features of cervical tuberculous lymphadenitis on serial neck computed tomography before and after chemotherapy: focus on the relation between clinical outcomes and computed tomography features. (16272869)
2005
37
Lymphadenitis caused by non-tuberculous mycobacteria in a university hospital in Taiwan: predominance of rapidly growing mycobacteria and high recurrence rate. (16607446)
2005
38
Kikuchi's disease (necrotizing lymphadenitis) with cutaneous involvement associated with subacute cutaneous lupus erythematosus. (15115501)
2004
39
Disseminated Mycobacterium abscessus infection manifesting as fever of unknown origin and intra-abdominal lymphadenitis: case report and literature review. (11173189)
2001
40
Cutaneous and mediastinal lymphadenitis due to Mycobacterium kansasii. (11545572)
2001
41
Cervical lymphadenitis and cat scratch disease (CSD): an overlooked disease? (11205454)
2000
42
Hodgkin's disease mimicking suppurative lymphadenitis: a fine-needle aspiration report of five cases. (10319233)
1999
43
Generalized suppurative lymphadenitis with typhoidal salmonellosis. (3211632)
1988
44
Tick-borne tularemia presenting as ulcerative lymphadenitis. (428180)
1979
45
Suppurative lymphadenitis following intradermal B.C.G. vaccination of the newborn; a preliminary report. (13260657)
1955
46
Symptomatic sprue due to nonspecific chronic jejunitis and mesenteric lymphadenitis. (13117209)
1953
47
Acute non-specific mesenteric lymphadenitis; incidence and prognosis in children. (14874429)
1951
48
Acute non-specific mesenteric lymphadenitis. (18117315)
1949
49
MESENTERIC LYMPHADENITIS. (17857365)
1939
50
Mesenteric Lymphadenitis and Its Clinical Manifestations. (20773581)
1927

Variations for Lymphadenitis

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Expression for genes affiliated with Lymphadenitis

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lymphadenitis

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Pathways for genes affiliated with Lymphadenitis

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Sources:
51PathCards, 31KEGG, 39NCBI BioSystems Database, 55R&D Systems
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Pathways related to Lymphadenitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.0IL12RB1, IFNGR1
2
Show member pathways
Type III interferon signaling39
9.0IL12RB1, IFNGR1
3
Show member pathways
IL27-mediated signaling events39
9.0IL12RB1, IFNGR1

Compounds for genes affiliated with Lymphadenitis

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46Novoseek
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Compounds related to Lymphadenitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1gp 130469.0IL12RB1, IFNGR1

GO Terms for genes affiliated with Lymphadenitis

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17Gene Ontology
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Cellular components related to Lymphadenitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.1PDCD1, IL12RB1

Biological processes related to Lymphadenitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1signal transductionGO:0071658.5PDCD1, IL12RB1, IFNGR1

Products for genes affiliated with Lymphadenitis

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Sources for Lymphadenitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet