MCID: LYM035
MIFTS: 28

Lymphangiectasis malady

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Lymphangiectasis

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Aliases & Descriptions for Lymphangiectasis:

Name: Lymphangiectasis 46 66
 
Lymphangiectasia 46

Classifications:



Summaries for Lymphangiectasis

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Wikipedia:69 Lymphangiectasia is a pathologic dilation of lymph vessels. When it occurs in the intestines of dogs,... more...

MalaCards based summary: Lymphangiectasis, also known as lymphangiectasia, is related to lymphangiomatosis and hennekam lymphangiectasia-lymphedema syndrome 1, and has symptoms including pain of lymph node An important gene associated with Lymphangiectasis is ACTC1 (Actin, Alpha, Cardiac Muscle 1), and among its related pathways are Cytoskeletal Signaling and Striated Muscle Contraction. Affiliated tissues include lymph node, breast and lung.

Related Diseases for Lymphangiectasis

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Diseases related to Lymphangiectasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1lymphangiomatosis29.5ACTC1, VIM
2hennekam lymphangiectasia-lymphedema syndrome 110.9
3lymphangiectasia, pulmonary, congenital10.9
4mullerian derivatives, persistence of, with lymphangiectasia and postaxial polydactyly10.9
5lymphangiectasia, intestinal10.9
6hennekam syndrome10.9
7primary intestinal lymphangiectasia10.9
8lymphangioma10.0
9breast cancer10.0
10myxoid liposarcoma of the ovary9.9ACTC1, VIM
11iridogoniodysgenesis and skeletal anomalies9.9ACTC1, VIM
12skin lipoma9.9ACTC1, VIM
13lymphangiosarcoma9.9ACTC1, VIM
14chondroblastoma9.9ACTC1, VIM
15pulmonary venoocclusive disease9.9ACTC1, VIM
16mollaret meningitis9.9ACTC1, VIM
17skin sarcoma9.9ACTC1, VIM
18vulvar alveolar soft part sarcoma9.9ACTC1, VIM
19osteomalacia9.9
20protein-losing enteropathy9.9
21constrictive pericarditis9.9
22pericarditis9.9
23peritonitis9.9
24eccrine papillary adenoma9.9ACTC1, VIM
25malignant peritoneal solitary fibrous tumor9.9ACTC1, VIM
26malignant glandular tumor of peripheral nerve sheath9.9ACTC1, VIM
27skin glomangioma9.9ACTC1, VIM
28pineal parenchymal tumor of intermediate differenciation9.9ACTC1, VIM
29ovarian cystadenocarcinoma9.9ACTC1, VIM
30parachordoma9.9ACTC1, VIM
31vascular hemostatic disease9.8ACTC1, VIM
32short-rib thoracic dysplasia 129.8ACTC1, VIM
33t-cell childhood acute lymphocytic leukemia9.8ACTC1, VIM
34paranasal sinus cancer, adult9.8ACTC1, VIM
35dens in dente and palatal invaginations9.8ACTC1, VIM
36staphyloenterotoxemia9.8ACTC1, VIM
37polyomavirus allograft nephropathy9.8ACTC1, VIM
38glioma susceptibility 19.8ACTC1, VIM
39gallbladder leiomyosarcoma9.8ACTC1, VIM
40frontal sinus squamous cell carcinoma9.8ACTC1, VIM
41osteoporosis9.7
42hemangioma9.7
43hepatitis9.7
44interstitial emphysema9.7
45hyperlucent lung9.7
46polydactyly9.7
47diarrhea9.7
48pneumothorax9.7
49melanoma9.7
50capillary hemangioma9.7

Graphical network of the top 20 diseases related to Lymphangiectasis:



Diseases related to lymphangiectasis

Symptoms for Lymphangiectasis

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UMLS symptoms related to Lymphangiectasis:


pain of lymph node

Drugs & Therapeutics for Lymphangiectasis

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Drugs for Lymphangiectasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
sirolimusPhase 2186353123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
2
MiconazolePhase 2357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
3
EverolimusPhase 21863159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus

Interventional clinical trials:

idNameStatusNCT IDPhase
1Safety and Efficacy Study of Sirolimus in Complicated Vascular AnomaliesActive, not recruitingNCT00975819Phase 2
2Characterization of the Pathogenesis of Primary and Secondary Lymphatic DisordersRecruitingNCT02156115
3National Lymphatic Disease and Lymphedema RegistryRecruitingNCT01336790

Search NIH Clinical Center for Lymphangiectasis

Genetic Tests for Lymphangiectasis

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Anatomical Context for Lymphangiectasis

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MalaCards organs/tissues related to Lymphangiectasis:

34
Lymph node, Breast, Lung, Endothelial, Testes, Colon, Spleen

Animal Models for Lymphangiectasis or affiliated genes

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Publications for Lymphangiectasis

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Articles related to Lymphangiectasis:

(show top 50)    (show all 119)
idTitleAuthorsYear
1
Severe primary pulmonary lymphangiectasis in a premature infant: management and follow up to early childhood. (25711257)
2015
2
Mildly progressive pulmonary lymphangiectasis diagnosed in a young adult. (24684358)
2014
3
Removal of lymphangiectasis using high-frequency radio wave electrosurgery. (22968357)
2013
4
Osteomalacia and osteoporosis associated with primary intestinal lymphangiectasis. (22800909)
2012
5
Congenital pulmonary lymphangiectasis: report of an autopsy case masquerading as pulmonary interstitial emphysema. (20399027)
2010
6
Combination technique of radiofrequency ablation with sclerotherapy in acquired lymphangiectasis of the vulva. (20300370)
2009
7
Lymphangiectasis of lower limb: A rare challenging case. (20368868)
2009
8
Pulmonary lymphangiectasis in an asymptomatic adult. (16179818)
2006
9
Endothelial, inducible and neuronal nitric oxide synthase in congenital pulmonary lymphangiectasis. (16772393)
2006
10
Acquired lymphangiectasis after breast conservation treatment for breast cancer: report of a case. (15347491)
2004
11
Unilobar congenital pulmonary lymphangiectasis mimicking congenital lobar emphysema: an underestimated presentation? (15136998)
2004
12
Autopsy case of congenital pulmonary lymphangiectasis. (15189509)
2004
13
Primary pulmonary lymphangiectasis in a premature infant: resolution following intensive care. (12687599)
2003
14
Chylous reflux into localized pulmonary lymphangiectasis. (12173851)
2002
15
Thoracic lymphangiectasis presenting with chyloptysis and bronchial cast expectoration. (12522631)
2002
16
Persistence of MA1llerian derivatives and intestinal lymphangiectasis in two newborn brothers: confirmation of the Urioste syndrome. (11746031)
2001
17
Lymphangiectasis with iniencephaly. (11844186)
2001
18
46,XY/46,XX mosaicism and congenital pulmonary lymphangiectasis with chylothorax. (8279494)
1993
19
Congenital pulmonary lymphangiectasis with chylothorax: a heterogeneous lymphatic vessel abnormality. (8368253)
1993
20
Conjunctival hemorrhagic lymphangiectasis. (3183282)
1988
21
Acquired cutaneous lymphangiectasis in a dog. (3198463)
1988
22
Premature closure of the foramen ovale and congenital pulmonary cystic lymphangiectasis in aortic valve atresia or in severe aortic valve stenosis. (3953463)
1986
23
Congenital pulmonary lymphangiectasis. A case complicated by chylothorax. (6848293)
1983
24
Airway obstruction due to epiglottic lymphangiectasis: a case report. (6676335)
1983
25
Familial occurrence of congenital pulmonary lymphangiectasis. Genetic implications. (7234788)
1981
26
Prenatal diagnosis of fetal cystic hygromas associated with generalized lymphangiectasis. (7263290)
1981
27
Case report--pregnancy and intestinal lymphangiectasis (familial neonatal hypoproteinaemia). (6930252)
1980
28
An immature stillbirth with lymphangiectasis and gonadal agenesis. (264098)
1979
29
Congenital pulmonary lymphangiectasis. (472852)
1979
30
Constrictive pericarditis and protein losing enteropathy. An imitator of intestinal lymphangiectasis. (1155672)
1975
31
A case of congenital pulmonary lymphangiectasis. (4278975)
1974
32
Congenital pulmonary lymphangiectasis. Report of two cases. (15822889)
1974
33
Congenital pulmonary lymphangiectasis. (5058157)
1972
34
Noonan syndrome with intestinal lymphangiectasis. A metabolic and anatomic study. (5008823)
1972
35
Congenital pulmonary lymphangiectasis. An emerging spectrum of neonatal and infantile lung disease. (5019919)
1972
36
Congenital pulmonary lymphangiectasis and ichthyosis congenita. A case report. (5410042)
1970
37
Irradiation-induced constrictive pericarditis in intestinal lymphangiectasis. (4322318)
1970
38
Acquired lymphangioma (lymphangiectasis). Report of a case. (5413258)
1970
39
Lymphangiectasis of penis: first reported case in the literature. (5343497)
1969
40
Congenital pulmonary lymphangiectasis. (5724880)
1968
41
Dubilier LD: Colonic lymphangiectasis associated with a potassium depletion syndrome. (5698630)
1968
42
Congenital pulmonary lymphangiectasis associated with a blind common pulmonary vein. (5654840)
1968
43
Congenital pulmonary lymphangiectasis. (5950669)
1966
44
LYMPHANGIECTASIS. BENIGN AND MALIGNANT. (14158223)
1964
45
LYMPHANGIECTASIS OF STOMACH SIMULATING POLYPOID NEOPLASM. (14090389)
1964
46
Congenital pulmonary lymphangiectasis. Report of a case with roentgen findings. (13691154)
1961
47
Congenital pulmonary cystic lymphangiectasis. (13824507)
1959
48
Congenital pulmonary lymphangiectasis. (13631084)
1959
49
Congenital pulmonary cystic lymphangiectasis. (13295907)
1955
50
Tumour Lymphangiectasis of the Lower Lid. (19978979)
1915

Variations for Lymphangiectasis

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Expression for genes affiliated with Lymphangiectasis

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Search GEO for disease gene expression data for Lymphangiectasis.

Pathways for genes affiliated with Lymphangiectasis

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Pathways related to Lymphangiectasis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1ACTC1, VIM
29.1ACTC1, VIM

GO Terms for genes affiliated with Lymphangiectasis

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Cellular components related to Lymphangiectasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1focal adhesionGO:00059259.1ACTC1, VIM

Biological processes related to Lymphangiectasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.1ACTC1, VIM
2positive regulation of gene expressionGO:00106289.1ACTC1, VIM

Sources for Lymphangiectasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet