MCID: LYM022
MIFTS: 54

Lymphangioma malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Lymphangioma

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Aliases & Descriptions for Lymphangioma:

Name: Lymphangioma 11 50 39 13 68
Congenital Lymphangioma 11
 
Benign Lymphangioma 11
Lymphangiomas 27

Classifications:



External Ids:

Disease Ontology11 DOID:1475
ICD1030 D18.1
ICD9CM32 228.1
MeSH39 D008202
NCIt45 C8965

Summaries for Lymphangioma

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Wikipedia:71 Lymphangiomas are malformations of the lymphatic system characterized by lesions that are thin-walled... more...

MalaCards based summary: Lymphangioma, also known as congenital lymphangioma, is related to lymphangiomatosis and lymphangiosarcoma, and has symptoms including pain of lymph node An important gene associated with Lymphangioma is FLT4 (Fms Related Tyrosine Kinase 4), and among its related pathways are VEGFR3 signaling in lymphatic endothelium and Angiogenesis (WikiPathways). Affiliated tissues include pancreas, lymph node and tongue, and related mouse phenotypes are Decreased cell migration and Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance.

Related Diseases for Lymphangioma

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Diseases related to Lymphangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 229)
idRelated DiseaseScoreTop Affiliating Genes
1lymphangiomatosis30.4ACTC1, VIM
2lymphangiosarcoma29.8ACTC1, VIM
3cystic lymphangioma12.2
4capillary lymphangioma12.0
5abdominal cystic lymphangioma12.0
6cavernous lymphangioma11.9
7colonic lymphangioma11.9
8orbital lymphangioma11.9
9primary laryngeal lymphangioma11.8
10microcystic lymphatic malformation11.7
11nuchal bleb, familial11.6
12lymphatic malformations11.4
13cobb syndrome11.1
14vascular malformation11.1
15mixed cystic lymphatic malformation11.1
16diffuse lymphatic malformation11.0
17adult cerebellar neoplasm10.6FLT4, PDPN
18sebaceous adenocarcinoma10.5FLT4, IFNA2
19hydromyelia10.5FLT4, VEGFA
20hemangioma, capillary infantile10.5FLT4, KDR
21hemangioma10.5
22bladder urachal carcinoma10.5KDR, VEGFA
23lymphocytes absent10.4FLT4, PROX1
24arthrogryposis, ectodermal dysplasia, cleft lip/palate, and developmental delay10.4KDR, VEGFA
25breast secretory carcinoma10.4PDPN, PROX1
26iliac vein thrombophlebitis10.4KDR, VEGFA
27pura syndrome10.4ACTC1, KDR
28hyperlucent lung10.4FLT4, PROX1
29gastric small cell carcinoma10.3KDR, VEGFA
30tooth erosion10.3KDR, VIM
31carcinoma of the vocal tract10.3IFNA2, VEGFA
32myxoid liposarcoma of the ovary10.3ACTC1, VIM
33kidney sarcoma10.3VEGFA, VIM
34lens disease10.3KDR, VEGFA
35skin lipoma10.3ACTC1, VIM
36chondroblastoma10.3ACTC1, VIM
37breast papillary carcinoma10.3EGFR, PDPN
38pulmonary venoocclusive disease10.3ACTC1, VIM
39mollaret meningitis10.3ACTC1, VIM
40skin sarcoma10.2ACTC1, VIM
41lung carcinoma in situ10.2FLT4, KDR, VEGFA
42vulvar alveolar soft part sarcoma10.2ACTC1, VIM
43eccrine papillary adenoma10.2ACTC1, VIM
44malignant peritoneal solitary fibrous tumor10.2ACTC1, VIM
45hematopoietic stem cell transplantation10.2FLT4, KDR, VEGFA
46mediastinitis10.2
47malignant glandular tumor of peripheral nerve sheath10.2ACTC1, VIM
48skin glomangioma10.2ACTC1, VIM
49lethal restrictive dermopathy, lmna-related10.2EGFR, VEGFA
50pineal parenchymal tumor of intermediate differenciation10.2ACTC1, VIM

Comorbidity relations with Lymphangioma via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Lymphangioma:



Diseases related to lymphangioma

Symptoms & Phenotypes for Lymphangioma

About this section

UMLS symptoms related to Lymphangioma:


pain of lymph node

GenomeRNAi Phenotypes related to Lymphangioma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00055-A-19.2EGFR, KDR, VEGFC, VIM
2GR00210-A9.1EGFR, VEGFA, VEGFC, VIM

MGI Mouse Phenotypes related to Lymphangioma according to GeneCards Suite gene sharing:

41 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.0EGFR, FLT4, KDR, PROX1, VEGFA
2MP:00053818.6EGFR, FLT4, PDPN, PROX1, SERPINF1, VEGFA
3MP:00028738.5ACTC1, EGFR, FLT4, KDR, PROX1, VEGFA
4MP:00053888.3EGFR, KDR, PDPN, PROX1, VEGFA, VIM
5MP:00053977.9EGFR, KDR, PDPN, PROX1, SERPINF1, VEGFA
6MP:00053697.8ACTC1, EGFR, FLT4, KDR, PDPN, VEGFA
7MP:00053917.4EGFR, KDR, PROX1, SERPINF1, VEGFA, VIM
8MP:00053767.3ACTC1, EGFR, FLT4, KDR, PDPN, PROX1
9MP:00053877.3EGFR, FLT4, KDR, PDPN, PROX1, SERPINF1
10MP:00107687.2ACTC1, EGFR, FLT4, KDR, PDPN, PROX1
11MP:00053856.8ACTC1, EGFR, FLT4, KDR, PDPN, PROX1

Drugs & Therapeutics for Lymphangioma

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Drugs for Lymphangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1PicibanilPhase 2, Phase 37
2
Octreotideapproved, investigationalPhase 221383150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
 
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate
3
EverolimusapprovedPhase 21896159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
4
Miconazoleapproved, investigational, vet_approvedPhase 2362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
5
Sirolimusapproved, investigationalPhase 2189653123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
6Vasodilator AgentsPhase 1, Phase 23438
7Sildenafil CitratePhase 1, Phase 2323171599-83-0
8Phosphodiesterase 5 InhibitorsPhase 1, Phase 2571
9Phosphodiesterase InhibitorsPhase 1, Phase 21254
10Antineoplastic Agents, HormonalPhase 25407
11Gastrointestinal AgentsPhase 28109
12Immunosuppressive AgentsPhase 212770
13Anti-Infective AgentsPhase 221402
14Antifungal AgentsPhase 23615
15Anti-Bacterial AgentsPhase 210884
16Antibiotics, AntitubercularPhase 26972
17CitrateNutraceuticalPhase 1, Phase 21106
18
Citric Acidnutraceutical, vet_approvedPhase 1, Phase 2110677-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
19
Marimastatapproved, investigationalPhase 14154039-60-8119031
Synonyms:
(2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(2-methylpropyl)butanediamide
(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoxy)propyl)carboyl)-2-hydroxy-5-methylhexanohydroxamic acid
(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoyl)propyl)carbamoyl)-2-hydroxy-5-methylhexanohydroxamic acid
(2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide
15039-60-8
154039-60-8
AC1L3O2N
BB 2516
BB-2516
C100342
 
C15H29N3O5
CHEBI:50662
CHEMBL279785
CID119031
D03795
DB00786
LS-45634
Marimastat
Marimastat (USAN/INN)
Marimastat [USAN]
UNII-D5EQV23TDS
20Trace ElementsPhase 15802
21
SeleniumPhase 11757782-49-2
Synonyms:
Selanediide
Selenide
 
Selenide(2-)
Selenium
Selenium ion (Se2+)
22AntioxidantsPhase 12928
23Protective AgentsPhase 17190
24MicronutrientsPhase 15802
25
PancrelipaseapprovedEarly Phase 193553608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
PA
 
Pancreatic alpha-amylase precursor
Pancrelipase (amylase
lipase
protease)
26pancreatinEarly Phase 1935
27Anesthetics9001

Interventional clinical trials:

(show all 15)
idNameStatusNCT IDPhase
1Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic MalformationsCompletedNCT00010452Phase 2, Phase 3
2A Study to Evaluate Sildenafil for the Treatment of Lymphatic MalformationsCompletedNCT01290484Phase 1, Phase 2
3Sildenafil for the Treatment of Lymphatic MalformationsRecruitingNCT02335242Phase 2
4Octreotide VS Placebo in Prevention of Salivary Fistulae After Post Radiation Salvage SurgeryRecruitingNCT02437825Phase 2
5Safety and Efficacy Study of Sirolimus in Complicated Vascular AnomaliesActive, not recruitingNCT00975819Phase 2
6Phase I Drug Trial for S/E of Marimastat in Disabling Malformations When no Other Options.CompletedNCT00261391Phase 1
7Selenium in the Treatment of Complicated Lymphatic MalformationsTerminatedNCT01212965Phase 1
8Diagnosis of Hemangiomas and Vascular MalformationsCompletedNCT00577213
9Lymphatic Anomalies RegistryRecruitingNCT02399527
10AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)RecruitingNCT02250456
11Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic LesionsRecruitingNCT02494388Early Phase 1
12Registry for Vascular Anomalies Associated With CoagulopathyRecruitingNCT00576888
13Airway Vascular LesionsActive, not recruitingNCT00866827
14Imaging of Lymphatic AnomaliesEnrolling by invitationNCT02744027
15Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic DisordersEnrolling by invitationNCT00833599

Search NIH Clinical Center for Lymphangioma


Cochrane evidence based reviews: lymphangioma

Genetic Tests for Lymphangioma

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Genetic tests related to Lymphangioma:

id Genetic test Affiliating Genes
1 Lymphangioma27

Anatomical Context for Lymphangioma

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MalaCards organs/tissues related to Lymphangioma:

36
Pancreas, Lymph node, Tongue, Colon, Spleen, Breast, Endothelial

Publications for Lymphangioma

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Articles related to Lymphangioma:

(show top 50)    (show all 970)
idTitleAuthorsYear
1
An adult case of lymphangioma of the hepatoduodenal ligament mimicking a hepatic cyst. (28050777)
2017
2
A Large Hemispherical Colon Lymphangioma. (28050035)
2017
3
Diagnosis of perinephric retroperitoneal lymphangioma supported by contrast-enhanced ultrasound (CEUS). (27716656)
2016
4
Lymphangioma-like Kaposi sarcoma. (27825645)
2016
5
Lymphangioma Circumscriptum: A Great Mimicker. (27803540)
2016
6
CT Appearance of Adrenal Cystic Lymphangioma: Radiologic-Pathologic Correlation. (26700338)
2016
7
Acquired lymphangiectasia (lymphangioma circumscriptum) of the vulva: Clinicopathologic study of 11 patients from a single institution and 67 from the literature. (26967121)
2016
8
Splenic cystic lymphangioma. (27318865)
2016
9
Splenic cystic lymphangioma with atypical ultrasound findings. (26703174)
2016
10
Giant retroperitoneal cystic lymphangioma in a patient with Eisenmenger syndrome. (26590885)
2016
11
Airway obstruction caused by rapid enlargement of cervical lymphangioma in a five-month-old boy. (27648270)
2016
12
An Interesting Association of Cystic Hygroma of the Neck and Lymphangioma Causing a Paediatric Swollen Tongue. (27069707)
2016
13
Lymphangioma Circumscriptum of the Vulva. (27502262)
2016
14
Volvulus of the jejunum on cystic lymphangioma: About a clinical case. (27251660)
2016
15
Minimally Invasive Management of Complex Recurrent Lymphangioma of the Thorax and Abdomen. (27211980)
2016
16
Lymphangioma of the ovary: etiology and management. (27401696)
2016
17
A rare case of acquired lymphangioma circumscriptum of the penis. (27330019)
2016
18
An Unusual Origin of Fetal Lymphangioma Filling Right Axilla. (27134953)
2016
19
Chylopericardium presenting as cardiac tamponade secondary to mediastinal lymphangioma. (27388545)
2016
20
Response to OK-432 sclerotherapy in the treatment of cervical lymphangioma with submucosal extension to the airway. (27297957)
2016
21
A Huge Cystic Retroperitoneal Lymphangioma Presenting with Back Pain. (27843456)
2016
22
Conjunctival lymphangioma in a 4-year-old girl revealed tuberous sclerosis complex. (27703871)
2016
23
Giant cystic lymphangioma originating from the cardia of the stomach: A case report. (27168832)
2016
24
Cystic Lymphangioma of Pancreas. (27065694)
2016
25
Lymphangioma Circumscriptum: Good Clinical Response to Isotretinoin Therapy. (27041148)
2016
26
Mesenteric lymphangioma mimicking a cystic ovarian mass on imaging. (26833955)
2016
27
Case report of solitary giant hepatic lymphangioma. (27212994)
2016
28
Lymphangioma circumscriptum of the male genitalia. (26955596)
2016
29
Classical Cases of Lymphangioma - As Multiple Vesicular Eruptions. (27504428)
2016
30
Case Report: Multivisceral Transplantation for an Extensive Cystic Lymphangioma of the Mesenteric Root. (27109997)
2016
31
Vulvar verruciform xanthoma developing in acquired lymphangioma circumscriptum. (27334742)
2016
32
Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Findings of Post Traumatic Lymphangioma in a Young Adult Male. (27699163)
2016
33
Acquired vulvar lymphangioma circumscriptum after cervical cancer treatment: Case report. (27331134)
2016
34
Emergency presentation of cystic lymphangioma of the colon: A case report and literature review. (27266826)
2016
35
High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience. (27329721)
2016
36
Metastatic rectal adenocarcinoma and anal squamous cell carcinoma masquerading as vulvar lymphangioma circumscriptum. (27616148)
2016
37
Excellent Result With the Use of Single-Dose OK-432 in Cervical Macrocystic Lymphangioma. (27513783)
2016
38
Lymphangioma-like Kaposi Sarcoma in Transplant-Associated Iatrogenic Immunosuppression: A Case Report. (27932165)
2016
39
Primary Lymphangioma of the Palatine Tonsil in a 9-Year-Old Boy: A Case Presentation and Literature Review. (27872780)
2016
40
Severe Pain and Edema due to a Widespread Lymphangioma: Disappearance of Symptoms and Reduction of Lesion with Spinal Cord Stimulation. (27402439)
2016
41
Abdominal lymphangioma. (28050075)
2016
42
Giant Omental Cyst (Lymphangioma) Mimicking Ascites and Tuberculosis. (27853495)
2016
43
Utility of conservative treatment in cystic lymphangioma. (27087134)
2016
44
Adult cystic lymphangioma in the inner quadrant of the breast-Rare location for a rare disease: A case report. (26852362)
2016
45
Sublingual lymphangioma that presented as a plunging ranula in a baby boy. (27068850)
2016
46
Cystic Lymphangioma of the Pancreas: a Rare Entity. (27334312)
2016
47
EP10.38: EXIT procedure in a neonate with lymphangioma diagnosed prenatally. (27647559)
2016
48
Laparoscopic Treatment of Intraabdominal Cystic Lymphangioma. (27452935)
2016
49
Pancreatic Lymphangioma as a Rare Pancreatic Mass: A Case Report. (27366308)
2016
50
A 36-Year-Old Female with Recurrent Left Sided Pleural Effusion: A Rare Case of Mediastinal Lymphangioma. (27789902)
2016

Variations for Lymphangioma

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Expression for genes affiliated with Lymphangioma

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Search GEO for disease gene expression data for Lymphangioma.

Pathways for genes affiliated with Lymphangioma

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Pathways related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 22)
idSuper pathwaysScoreTop Affiliating Genes
19.9FLT4, VEGFC
2
Show member pathways
9.6KDR, VEGFA
3
Show member pathways
9.2FLT4, KDR, PROX1, VEGFC
4
Show member pathways
9.1FLT4, KDR, VEGFA, VEGFC
5
Show member pathways
9.1FLT4, KDR, VEGFA, VEGFC
6
Show member pathways
9.1FLT4, KDR, VEGFA, VEGFC
7
Show member pathways
9.0EGFR, FLT4, KDR
88.8EGFR, KDR, VEGFA
98.8EGFR, KDR, VEGFA
108.7KDR, PROX1, VEGFA, VIM
11
Show member pathways
8.7EGFR, FLT4, KDR, VEGFC
12
Show member pathways
8.7EGFR, FLT4, KDR, VEGFC
138.7EGFR, FLT4, KDR, VEGFC
148.5EGFR, FLT4, KDR, VEGFA
15
Show member pathways
8.2EGFR, FLT4, KDR, VEGFA, VEGFC
168.2EGFR, FLT4, KDR, VEGFA, VEGFC
17
Show member pathways
8.2EGFR, FLT4, KDR, VEGFA, VEGFC
18
Show member pathways
8.2EGFR, FLT4, KDR, VEGFA, VEGFC
19
Show member pathways
7.8EGFR, FLT4, IFNA2, KDR, VEGFA, VEGFC
207.8EGFR, FLT4, IFNA2, KDR, VEGFA, VEGFC
21
Show member pathways
7.6EGFR, FLT4, KDR, VEGFA, VEGFC, VIM
22
Show member pathways
7.3EGFR, FLT4, IFNA2, KDR, SERPINF1, VEGFA

GO Terms for genes affiliated with Lymphangioma

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Cellular components related to Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.8FLT4, IFNA2, KDR, SERPINF1, VEGFA, VEGFC
2extracellular spaceGO:00056157.4ACTC1, EGFR, IFNA2, SERPINF1, VEGFA, VEGFC

Biological processes related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 33)
idNameGO IDScoreTop Affiliating Genes
1lymph vessel developmentGO:000194510.6FLT4, PROX1
2induction of positive chemotaxisGO:005093010.5VEGFA, VEGFC
3positive chemotaxisGO:005091810.5VEGFA, VEGFC
4positive regulation of blood vessel endothelial cell migrationGO:004353610.5VEGFA, VEGFC
5cell migration involved in sprouting angiogenesisGO:000204210.4KDR, VEGFA
6positive regulation of protein kinase C signalingGO:009003710.4FLT4, VEGFA
7positive regulation of neuroblast proliferationGO:000205210.4VEGFA, VEGFC
8positive regulation of protein autophosphorylationGO:003195410.4VEGFA, VEGFC
9positive regulation of cellular component movementGO:005127210.4PDPN, VEGFA
10positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwayGO:003803310.3KDR, VEGFA
11positive regulation of focal adhesion assemblyGO:005189410.3KDR, VEGFA
12positive regulation of positive chemotaxisGO:005092710.3KDR, VEGFA
13lymphangiogenesisGO:000194610.3FLT4, PDPN, PROX1
14skeletal muscle thin filament assemblyGO:003024010.1ACTC1, PROX1
15cellular response to vascular endothelial growth factor stimulusGO:003592410.1FLT4, KDR, VEGFA
16positive regulation of angiogenesisGO:004576610.1KDR, VEGFA, VEGFC
17kidney developmentGO:00018229.9PROX1, SERPINF1, VEGFA
18positive regulation of phosphorylationGO:00423279.9EGFR, IFNA2
19cellular response to dexamethasone stimulusGO:00715499.9EGFR, SERPINF1
20ovulation cycleGO:00426989.9EGFR, SERPINF1
21regulation of cell shapeGO:00083609.8KDR, PDPN, VEGFA
22positive regulation of endothelial cell migrationGO:00105959.7FLT4, KDR, PROX1, VEGFA
23peptidyl-tyrosine phosphorylationGO:00181089.7EGFR, FLT4, KDR
24positive regulation of endothelial cell proliferationGO:00019389.7FLT4, KDR, PROX1, VEGFA
25positive regulation of ERK1 and ERK2 cascadeGO:00703749.7EGFR, FLT4, KDR
26protein autophosphorylationGO:00467779.6EGFR, FLT4, KDR
27positive regulation of epithelial cell proliferationGO:00506799.6EGFR, VEGFA, VEGFC
28positive regulation of cell migrationGO:00303359.5EGFR, KDR, VEGFA
29lung developmentGO:00303249.3EGFR, PDPN, PROX1, VEGFA
30positive regulation of protein phosphorylationGO:00019349.2EGFR, FLT4, KDR, VEGFA
31vascular endothelial growth factor receptor signaling pathwayGO:00480109.1FLT4, KDR, VEGFA, VEGFC
32negative regulation of apoptotic processGO:00430668.8ACTC1, EGFR, FLT4, KDR, VEGFA
33positive regulation of cell proliferationGO:00082848.6EGFR, FLT4, KDR, PROX1, VEGFA, VEGFC

Molecular functions related to Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth factor bindingGO:001983810.3FLT4, KDR
2chemoattractant activityGO:004205610.2VEGFA, VEGFC
3vascular endothelial growth factor-activated receptor activityGO:00050219.8FLT4, KDR
4transmembrane receptor protein tyrosine kinase activityGO:00047149.2EGFR, FLT4, KDR

Sources for Lymphangioma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet