MCID: LYM022
MIFTS: 54

Lymphangioma malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Lymphangioma

Aliases & Descriptions for Lymphangioma:

Name: Lymphangioma 12 52 42 14 69
Congenital Lymphangioma 12
Benign Lymphangioma 12
Lymphangiomas 29

Classifications:



External Ids:

Disease Ontology 12 DOID:1475
ICD10 33 D18.1
ICD9CM 35 228.1
MeSH 42 D008202
NCIt 47 C8965
UMLS 69 C0024221

Summaries for Lymphangioma

MalaCards based summary : Lymphangioma, also known as congenital lymphangioma, is related to cystic lymphangioma and abdominal cystic lymphangioma. An important gene associated with Lymphangioma is FLT4 (Fms Related Tyrosine Kinase 4), and among its related pathways/superpathways are PEDF Induced Signaling and TGF-Beta Pathway. The drugs Picibanil and Octreotide have been mentioned in the context of this disorder. Affiliated tissues include pancreas, tongue and lymph node, and related phenotypes are Decreased cell migration and Increased cell migration

Wikipedia : 71 Lymphangiomas are malformations of the lymphatic system characterized by lesions that are thin-walled... more...

Related Diseases for Lymphangioma

Diseases related to Lymphangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 224)
id Related Disease Score Top Affiliating Genes
1 cystic lymphangioma 12.2
2 abdominal cystic lymphangioma 12.2
3 capillary lymphangioma 12.0
4 microcystic lymphatic malformation 12.0
5 cavernous lymphangioma 11.9
6 colonic lymphangioma 11.9
7 lymphatic malformations 11.9
8 orbital lymphangioma 11.9
9 primary laryngeal lymphangioma 11.8
10 nuchal bleb, familial 11.6
11 cobb syndrome 11.1
12 vascular malformation 11.1
13 mixed cystic lymphatic malformation 11.1
14 diffuse lymphatic malformation 11.0
15 hemangioma 10.5
16 intrahepatic cholangiocarcinoma 10.3 PDPN PROX1
17 phencyclidine abuse 10.3 FLT4 PDPN
18 gapo syndrome 10.3 FLT4 KDR
19 eosinophilic pneumonia 10.3 FLT4 KDR
20 hemiplegic migraine 10.2 FLT4 KDR
21 aniridia - ptosis - intellectual disability - familial obesity 10.2 KDR VEGFC
22 malignant conjunctival melanoma 10.2 IFNA2 PDPN
23 mediastinitis 10.2
24 intracranial cysts 10.2 FLT4 VEGFA
25 congenital myasthenic syndrome associated with acetylcholine receptor deficiency 10.2 FLT4 PDPN VEGFC
26 oculodentodigital dysplasia 10.2 FLT4 PROX1 VEGFC
27 chromosome 18 pericentric inversion 10.2 FLT4 PROX1 VEGFC
28 acrofacial dysostosis, patagonia type 10.2 FLT4 PROX1 VEGFC
29 aortic aneurysm 10.2 VEGFA VEGFC
30 cycloplegia 10.2 FLT4 PROX1
31 orofaciodigital syndrome 13 10.2 EGFR FLT4 PDPN
32 kidney osteogenic sarcoma 10.2 KDR VEGFA
33 retiform hemangioendothelioma 10.2
34 cavernous hemangioma 10.2
35 kaposiform hemangioendothelioma 10.2
36 keratosis follicularis spinulosa decalvans 10.2 FLT4 KDR PROX1
37 renal agenesis meningomyelocele mullerian defect 10.2 EGFR IFNA2
38 pancreatitis 10.2
39 congenital myasthenic syndrome 10.1 ACTC1 VEGFC
40 liddle syndrome, scnn1g-related 10.1 EGFR VEGFA
41 hand, foot and mouth disease 10.1 KDR VEGFA
42 hypomelanosis of ito 10.1 FLT4 IFNA2 PROX1
43 pilomyxoid astrocytoma 10.1 FLT4 IFNA2 PROX1
44 central cervical cord syndrome 10.1 FLT4 IFNA2 PROX1
45 cone-rod dystrophy 17 10.1 KDR VEGFA
46 cervicitis 10.1
47 vesiculobullous skin disease 10.1 FLT4 KDR VEGFA
48 factitious disorder 10.1 FLT4 KDR VEGFA
49 ovarian cystadenocarcinoma 10.1 EGFR VEGFA
50 isolated anterior cervical hypertrichosis 10.1 ACTC1 VEGFA

Graphical network of the top 20 diseases related to Lymphangioma:



Diseases related to Lymphangioma

Symptoms & Phenotypes for Lymphangioma

GenomeRNAi Phenotypes related to Lymphangioma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 9.26 EGFR KDR PIK3CA VEGFC
2 Increased cell migration GR00055-A-3 8.92 EGFR KDR PIK3CA VEGFC

MGI Mouse Phenotypes related to Lymphangioma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.18 ACTC1 EGFR FLT4 KDR PDPN PIK3CA
2 homeostasis/metabolism MP:0005376 10.06 ACTC1 EGFR FLT4 KDR PDPN PIK3CA
3 growth/size/body region MP:0005378 10.03 ACTC1 EGFR FLT4 KDR PDPN PIK3CA
4 immune system MP:0005387 10.02 EGFR FLT4 KDR PDPN PIK3CA PROX1
5 digestive/alimentary MP:0005381 9.93 PROX1 SERPINF1 VEGFA EGFR FLT4 PDPN
6 mortality/aging MP:0010768 9.91 ACTC1 EGFR FLT4 KDR PDPN PIK3CA
7 integument MP:0010771 9.8 FLT4 KDR PDPN PIK3CA VEGFA EGFR
8 muscle MP:0005369 9.7 ACTC1 EGFR FLT4 KDR PDPN PIK3CA
9 normal MP:0002873 9.43 ACTC1 EGFR FLT4 KDR PROX1 VEGFA
10 vision/eye MP:0005391 9.1 EGFR KDR PIK3CA PROX1 SERPINF1 VEGFA

Drugs & Therapeutics for Lymphangioma

Drugs for Lymphangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Picibanil Phase 2, Phase 3
2
Octreotide Approved, Investigational Phase 2 83150-76-9 383414 6400441
3
Everolimus Approved Phase 2 159351-69-6 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
6 Phosphodiesterase 5 Inhibitors Phase 1, Phase 2
7 Phosphodiesterase Inhibitors Phase 1, Phase 2
8 Sildenafil Citrate Phase 1, Phase 2 171599-83-0
9 Vasodilator Agents Phase 1, Phase 2
10 Antineoplastic Agents, Hormonal Phase 2
11 Gastrointestinal Agents Phase 2
12 Anti-Bacterial Agents Phase 2
13 Antibiotics, Antitubercular Phase 2
14 Antifungal Agents Phase 2
15 Anti-Infective Agents Phase 2
16 Immunosuppressive Agents Phase 2
17 Citrate Nutraceutical Phase 1, Phase 2
18
Citric Acid Nutraceutical, Vet_approved Phase 1, Phase 2 77-92-9 311
19
Marimastat Approved, Investigational Phase 1 154039-60-8 119031
20
Selenium Approved, Vet_approved Phase 1 7782-49-2
21 Antioxidants Phase 1
22 Micronutrients Phase 1
23 Protective Agents Phase 1
24 Trace Elements Phase 1
25
Pancrelipase Approved Early Phase 1 53608-75-6
26 pancreatin Early Phase 1
27 Anesthetics

Interventional clinical trials:

(show all 15)
id Name Status NCT ID Phase
1 Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic Malformations Completed NCT00010452 Phase 2, Phase 3
2 A Study to Evaluate Sildenafil for the Treatment of Lymphatic Malformations Completed NCT01290484 Phase 1, Phase 2
3 Sildenafil for the Treatment of Lymphatic Malformations Recruiting NCT02335242 Phase 2
4 Octreotide VS Placebo in Prevention of Salivary Fistulae After Post Radiation Salvage Surgery Recruiting NCT02437825 Phase 2
5 Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies Active, not recruiting NCT00975819 Phase 2
6 Phase I Drug Trial for S/E of Marimastat in Disabling Malformations When no Other Options. Completed NCT00261391 Phase 1
7 Selenium in the Treatment of Complicated Lymphatic Malformations Terminated NCT01212965 Phase 1
8 Diagnosis of Hemangiomas and Vascular Malformations Completed NCT00577213
9 Lymphatic Anomalies Registry Recruiting NCT02399527
10 AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome) Recruiting NCT02250456
11 Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions Recruiting NCT02494388 Early Phase 1
12 Registry for Vascular Anomalies Associated With Coagulopathy Recruiting NCT00576888
13 Airway Vascular Lesions Active, not recruiting NCT00866827
14 Imaging of Lymphatic Anomalies Enrolling by invitation NCT02744027
15 Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders Enrolling by invitation NCT00833599

Search NIH Clinical Center for Lymphangioma

Cochrane evidence based reviews: lymphangioma

Genetic Tests for Lymphangioma

Genetic tests related to Lymphangioma:

id Genetic test Affiliating Genes
1 Lymphangioma 29

Anatomical Context for Lymphangioma

MalaCards organs/tissues related to Lymphangioma:

39
Pancreas, Tongue, Lymph Node, Colon, Spleen, Breast, Endothelial

Publications for Lymphangioma

Articles related to Lymphangioma:

(show top 50) (show all 971)
id Title Authors Year
1
An adult case of lymphangioma of the hepatoduodenal ligament mimicking a hepatic cyst. ( 28050777 )
2017
2
A Large Hemispherical Colon Lymphangioma. ( 28050035 )
2017
3
Lymphangioma-like classic Kaposi sarcoma. ( 28188608 )
2017
4
Drop-Attacks Revealing a Cervical Cystic Lymphangioma. ( 26620381 )
2016
5
Rapid growing pulmonary cavernous lymphangioma after chronic process for ten years. ( 27614339 )
2016
6
CT Appearance of Adrenal Cystic Lymphangioma: Radiologic-Pathologic Correlation. ( 26700338 )
2016
7
Metastatic rectal adenocarcinoma and anal squamous cell carcinoma masquerading as vulvar lymphangioma circumscriptum. ( 27616148 )
2016
8
Lymphangioma of the ovary: etiology and management. ( 27401696 )
2016
9
A Huge Cystic Retroperitoneal Lymphangioma Presenting with Back Pain. ( 27843456 )
2016
10
Case report of solitary giant hepatic lymphangioma. ( 27212994 )
2016
11
Splenic cystic lymphangioma. ( 27318865 )
2016
12
Giant cystic lymphangioma originating from the cardia of the stomach: A case report. ( 27168832 )
2016
13
Classical Cases of Lymphangioma - As Multiple Vesicular Eruptions. ( 27504428 )
2016
14
Minimally Invasive Management of Complex Recurrent Lymphangioma of the Thorax and Abdomen. ( 27211980 )
2016
15
Small intestinal and mesenteric lymphangioma in an adult: a rare cause of acute abdominal pain. ( 27723387 )
2016
16
Giant Omental Cyst (Lymphangioma) Mimicking Ascites and Tuberculosis. ( 27853495 )
2016
17
Diagnosis of cystic lymphangioma of the colon by endoscopic ultrasound: Biopsy is not needed! ( 27803907 )
2016
18
Lymphangioma circumscriptum of the male genitalia. ( 26955596 )
2016
19
Cystic Lymphangioma of Pancreas. ( 27065694 )
2016
20
An Interesting Association of Cystic Hygroma of the Neck and Lymphangioma Causing a Paediatric Swollen Tongue. ( 27069707 )
2016
21
Conjunctival lymphangioma in a 4-year-old girl revealed tuberous sclerosis complex. ( 27703871 )
2016
22
Abdominal lymphangioma. ( 28050075 )
2016
23
Adult cystic lymphangioma in the inner quadrant of the breast-Rare location for a rare disease: A case report. ( 26852362 )
2016
24
High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience. ( 27329721 )
2016
25
Sublingual lymphangioma that presented as a plunging ranula in a baby boy. ( 27068850 )
2016
26
Chylopericardium presenting as cardiac tamponade secondary to mediastinal lymphangioma. ( 27388545 )
2016
27
Laparoscopic Treatment of Intraabdominal Cystic Lymphangioma. ( 27452935 )
2016
28
Response to OK-432 sclerotherapy in the treatment of cervical lymphangioma with submucosal extension to the airway. ( 27297957 )
2016
29
Cystic Lymphangioma of the Pancreas: a Rare Entity. ( 27334312 )
2016
30
Lymphangioma Circumscriptum of the Vulva. ( 27502262 )
2016
31
An Unusual Origin of Fetal Lymphangioma Filling Right Axilla. ( 27134953 )
2016
32
Lymphangioma Circumscriptum: A Great Mimicker. ( 27803540 )
2016
33
A 36-Year-Old Female with Recurrent Left Sided Pleural Effusion: A Rare Case of Mediastinal Lymphangioma. ( 27789902 )
2016
34
Vulvar verruciform xanthoma developing in acquired lymphangioma circumscriptum. ( 27334742 )
2016
35
Mesenteric lymphangioma mimicking a cystic ovarian mass on imaging. ( 26833955 )
2016
36
A Giant Retroperitoneal Lymphangioma: A Case Report. ( 27630902 )
2016
37
Primary Lymphangioma of the Palatine Tonsil in a 9-Year-Old Boy: A Case Presentation and Literature Review. ( 27872780 )
2016
38
Intradural cavernous lymphangioma of the thoracic spine: case report, technical considerations, and review of the literature. ( 26970599 )
2016
39
Severe Pain and Edema due to a Widespread Lymphangioma: Disappearance of Symptoms and Reduction of Lesion with Spinal Cord Stimulation. ( 27402439 )
2016
40
EP10.38: EXIT procedure in a neonate with lymphangioma diagnosed prenatally. ( 27647559 )
2016
41
Diagnosis of perinephric retroperitoneal lymphangioma supported by contrast-enhanced ultrasound (CEUS). ( 27716656 )
2016
42
Emergency presentation of cystic lymphangioma of the colon: A case report and literature review. ( 27266826 )
2016
43
Retroperitoneal lymphangioma: A report of 2 cases and a review of the literature regarding the differential diagnoses of retroperitoneal cystic masses. ( 27123082 )
2016
44
Lymphangioma-like Kaposi sarcoma. ( 27825645 )
2016
45
Lymphangioma Circumscriptum: Good Clinical Response to Isotretinoin Therapy. ( 27041148 )
2016
46
Giant retroperitoneal cystic lymphangioma in a patient with Eisenmenger syndrome. ( 26590885 )
2016
47
Utility of conservative treatment in cystic lymphangioma. ( 27087134 )
2016
48
Lymphangioma-like Kaposi Sarcoma in Transplant-Associated Iatrogenic Immunosuppression: A Case Report. ( 27932165 )
2016
49
A rare case of acquired lymphangioma circumscriptum of the penis. ( 27330019 )
2016
50
Volvulus of the jejunum on cystic lymphangioma: About a clinical case. ( 27251660 )
2016

Variations for Lymphangioma

Expression for Lymphangioma

Search GEO for disease gene expression data for Lymphangioma.

Pathways for Lymphangioma

Pathways related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 40)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.5 EGFR FLT4 IFNA2 KDR SERPINF1 VEGFA
2
Show member pathways
13.36 EGFR FLT4 IFNA2 KDR PIK3CA VEGFA
3
Show member pathways
13.12 EGFR FLT4 KDR VEGFA VEGFC
4
Show member pathways
12.88 EGFR FLT4 KDR PIK3CA VEGFA
5
Show member pathways
12.7 EGFR FLT4 KDR PIK3CA VEGFA VEGFC
6
Show member pathways
12.66 EGFR KDR PIK3CA VEGFA
7
Show member pathways
12.57 EGFR FLT4 KDR VEGFC
8 12.54 EGFR PIK3CA VEGFA VEGFC
9
Show member pathways
12.49 EGFR FLT4 KDR PIK3CA VEGFA VEGFC
10
Show member pathways
12.46 FLT4 KDR PIK3CA VEGFA VEGFC
11
Show member pathways
12.37 EGFR FLT4 KDR PIK3CA
12
Show member pathways
12.31 EGFR FLT4 KDR PIK3CA
13
Show member pathways
12.21 EGFR FLT4 KDR VEGFA VEGFC
14 12.18 EGFR KDR PIK3CA VEGFA
15
Show member pathways
12.09 EGFR FLT4 KDR VEGFA VEGFC
16
Show member pathways
12.08 EGFR KDR VEGFA VEGFC
17
Show member pathways
12.06 EGFR FLT4 KDR
18
Show member pathways
11.98 EGFR PIK3CA VEGFA
19 11.97 KDR PIK3CA VEGFA
20 11.96 EGFR FLT4 KDR VEGFC
21 11.95 KDR PROX1 VEGFA
22 11.94 EGFR IFNA2 PIK3CA
23 11.8 PIK3CA VEGFA VEGFC
24 11.8 EGFR PIK3CA VEGFA
25 11.7 EGFR FLT4 IFNA2 KDR PIK3CA VEGFA
26
Show member pathways
11.69 FLT4 KDR PIK3CA
27 11.64 FLT4 KDR PROX1 VEGFC
28
Show member pathways
11.61 EGFR FLT4 KDR
29
Show member pathways
11.52 FLT4 KDR PIK3CA VEGFA VEGFC
30 11.42 KDR PIK3CA VEGFA
31 11.39 KDR PIK3CA VEGFA
32
Show member pathways
11.18 EGFR KDR PIK3CA VEGFA
33 11.17 EGFR PIK3CA
34 11.11 EGFR PIK3CA
35 11.07 EGFR PIK3CA
36 11.05 KDR PIK3CA VEGFA
37 11.01 FLT4 PIK3CA VEGFC
38 10.94 EGFR PIK3CA
39 10.57 VEGFA VEGFC
40
Show member pathways
10.46 FLT4 KDR VEGFA VEGFC

GO Terms for Lymphangioma

Cellular components related to Lymphangioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 EGFR FLT4 IFNA2 KDR SERPINF1 VEGFA
2 lamellipodium GO:0030027 9.33 ACTC1 PDPN PIK3CA
3 extracellular space GO:0005615 9.1 ACTC1 EGFR IFNA2 SERPINF1 VEGFA VEGFC

Biological processes related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 38)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.89 ACTC1 EGFR FLT4 KDR VEGFA
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.85 EGFR FLT4 KDR
3 positive regulation of cell migration GO:0030335 9.85 EGFR KDR VEGFA
4 positive regulation of cell proliferation GO:0008284 9.85 EGFR FLT4 KDR PROX1 VEGFA VEGFC
5 protein autophosphorylation GO:0046777 9.84 EGFR FLT4 KDR
6 peptidyl-tyrosine phosphorylation GO:0018108 9.84 EGFR FLT4 KDR
7 regulation of cell shape GO:0008360 9.81 KDR PDPN VEGFA
8 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.8 EGFR FLT4 KDR
9 positive regulation of angiogenesis GO:0045766 9.79 KDR VEGFA VEGFC
10 positive regulation of protein phosphorylation GO:0001934 9.78 EGFR FLT4 KDR VEGFA
11 kidney development GO:0001822 9.77 PROX1 SERPINF1 VEGFA
12 liver development GO:0001889 9.75 EGFR PIK3CA PROX1
13 angiogenesis GO:0001525 9.72 FLT4 KDR PIK3CA VEGFA VEGFC
14 positive regulation of epithelial cell proliferation GO:0050679 9.71 EGFR VEGFA VEGFC
15 lung development GO:0030324 9.71 EGFR PDPN PROX1 VEGFA
16 positive regulation of phosphorylation GO:0042327 9.68 EGFR IFNA2
17 positive regulation of focal adhesion assembly GO:0051894 9.66 KDR VEGFA
18 positive regulation of protein autophosphorylation GO:0031954 9.65 VEGFA VEGFC
19 positive regulation of blood vessel endothelial cell migration GO:0043536 9.65 VEGFA VEGFC
20 vasculature development GO:0001944 9.65 FLT4 PIK3CA
21 positive regulation of neuroblast proliferation GO:0002052 9.64 VEGFA VEGFC
22 cell migration involved in sprouting angiogenesis GO:0002042 9.63 KDR VEGFA
23 induction of positive chemotaxis GO:0050930 9.62 VEGFA VEGFC
24 lymph vessel development GO:0001945 9.61 FLT4 PROX1
25 positive regulation of positive chemotaxis GO:0050927 9.61 KDR VEGFA
26 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.61 FLT4 KDR VEGFA
27 positive regulation of cellular component movement GO:0051272 9.59 PDPN VEGFA
28 ovulation cycle GO:0042698 9.58 EGFR SERPINF1
29 positive regulation of protein kinase C signaling GO:0090037 9.57 FLT4 VEGFA
30 vascular endothelial growth factor signaling pathway GO:0038084 9.56 FLT4 KDR
31 positive regulation of mast cell chemotaxis GO:0060754 9.55 VEGFA VEGFC
32 skeletal muscle thin filament assembly GO:0030240 9.52 ACTC1 PROX1
33 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.51 KDR VEGFA
34 positive regulation of endothelial cell migration GO:0010595 9.46 FLT4 KDR PROX1 VEGFA
35 lymphangiogenesis GO:0001946 9.43 FLT4 PDPN PROX1
36 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.35 FLT4 KDR PIK3CA VEGFA VEGFC
37 positive regulation of endothelial cell proliferation GO:0001938 9.02 FLT4 KDR PROX1 VEGFA VEGFC
38 multicellular organism development GO:0007275 10 EGFR KDR PDPN PROX1 SERPINF1 VEGFA

Molecular functions related to Lymphangioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.43 EGFR FLT4 KDR
2 chemoattractant activity GO:0042056 9.32 VEGFA VEGFC
3 signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.16 EGFR KDR
4 vascular endothelial growth factor-activated receptor activity GO:0005021 8.96 FLT4 KDR
5 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.8 EGFR FLT4 KDR

Sources for Lymphangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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