MCID: LYM022
MIFTS: 54

Lymphangioma malady

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Lymphangioma

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Aliases & Descriptions for Lymphangioma:

Name: Lymphangioma 11 50 39 13 68
Congenital Lymphangioma 11
 
Benign Lymphangioma 11
Lymphangiomas 27

Classifications:



External Ids:

Disease Ontology11 DOID:1475
ICD1030 D18.1
ICD9CM32 228.1
MeSH39 D008202
NCIt45 C8965

Summaries for Lymphangioma

About this section
Wikipedia:71 Lymphangiomas are malformations of the lymphatic system characterized by lesions that are thin-walled... more...

MalaCards based summary: Lymphangioma, also known as congenital lymphangioma, is related to cystic lymphangioma and abdominal cystic lymphangioma. An important gene associated with Lymphangioma is FLT4 (Fms Related Tyrosine Kinase 4), and among its related pathways are miR-148a/miR-31/FIH1/HIF1andalpha;-Notch signaling in glioblastoma and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include pancreas, tongue and lymph node, and related mouse phenotypes are Decreased cell migration and Increased cell migration.

Related Diseases for Lymphangioma

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Diseases related to Lymphangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 224)
idRelated DiseaseScoreTop Affiliating Genes
1cystic lymphangioma12.2
2abdominal cystic lymphangioma12.2
3capillary lymphangioma12.0
4microcystic lymphatic malformation12.0
5cavernous lymphangioma11.9
6colonic lymphangioma11.9
7lymphatic malformations11.9
8orbital lymphangioma11.9
9primary laryngeal lymphangioma11.8
10nuchal bleb, familial11.6
11cobb syndrome11.1
12vascular malformation11.1
13mixed cystic lymphatic malformation11.1
14diffuse lymphatic malformation11.0
15hemangioma10.5
16intrahepatic cholangiocarcinoma10.3PDPN, PROX1
17phencyclidine abuse10.3FLT4, PDPN
18gapo syndrome10.3FLT4, KDR
19eosinophilic pneumonia10.3FLT4, KDR
20hemiplegic migraine10.2FLT4, KDR
21aniridia - ptosis - intellectual disability - familial obesity10.2KDR, VEGFC
22malignant conjunctival melanoma10.2IFNA2, PDPN
23mediastinitis10.2
24intracranial cysts10.2FLT4, VEGFA
25congenital myasthenic syndrome associated with acetylcholine receptor deficiency10.2FLT4, PDPN, VEGFC
26oculodentodigital dysplasia10.2FLT4, PROX1, VEGFC
27chromosome 18 pericentric inversion10.2FLT4, PROX1, VEGFC
28acrofacial dysostosis, patagonia type10.2FLT4, PROX1, VEGFC
29aortic aneurysm10.2VEGFA, VEGFC
30cycloplegia10.2FLT4, PROX1
31orofaciodigital syndrome 1310.2EGFR, FLT4, PDPN
32kidney osteogenic sarcoma10.2KDR, VEGFA
33cavernous hemangioma10.2
34kaposiform hemangioendothelioma10.2
35retiform hemangioendothelioma10.2
36keratosis follicularis spinulosa decalvans10.2FLT4, KDR, PROX1
37renal agenesis meningomyelocele mullerian defect10.2EGFR, IFNA2
38pancreatitis10.2
39congenital myasthenic syndrome10.1ACTC1, VEGFC
40liddle syndrome, scnn1g-related10.1EGFR, VEGFA
41hand, foot and mouth disease10.1KDR, VEGFA
42hypomelanosis of ito10.1FLT4, IFNA2, PROX1
43pilomyxoid astrocytoma10.1FLT4, IFNA2, PROX1
44central cervical cord syndrome10.1FLT4, IFNA2, PROX1
45cone-rod dystrophy 1710.1KDR, VEGFA
46cervicitis10.1
47vesiculobullous skin disease10.1FLT4, KDR, VEGFA
48factitious disorder10.1FLT4, KDR, VEGFA
49ovarian cystadenocarcinoma10.1EGFR, VEGFA
50isolated anterior cervical hypertrichosis10.1ACTC1, VEGFA

Graphical network of the top 20 diseases related to Lymphangioma:



Diseases related to lymphangioma

Symptoms & Phenotypes for Lymphangioma

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GenomeRNAi Phenotypes related to Lymphangioma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00055-A-19.2EGFR, KDR, PIK3CA, VEGFC
2GR00055-A-39.2EGFR, KDR, PIK3CA, VEGFC

MGI Mouse Phenotypes related to Lymphangioma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.8EGFR, FLT4, PDPN, PROX1, SERPINF1, VEGFA
2MP:00028738.6ACTC1, EGFR, FLT4, KDR, PROX1, VEGFA
3MP:00107718.4EGFR, FLT4, KDR, PDPN, PIK3CA, VEGFA
4MP:00053697.8ACTC1, EGFR, FLT4, KDR, PDPN, PIK3CA
5MP:00053787.6ACTC1, EGFR, FLT4, KDR, PDPN, PIK3CA
6MP:00053917.4EGFR, KDR, PIK3CA, PROX1, SERPINF1, VEGFA
7MP:00053767.3ACTC1, EGFR, FLT4, KDR, PDPN, PIK3CA
8MP:00053877.3EGFR, FLT4, KDR, PDPN, PIK3CA, PROX1
9MP:00107687.2ACTC1, EGFR, FLT4, KDR, PDPN, PIK3CA
10MP:00053856.8ACTC1, EGFR, FLT4, KDR, PDPN, PIK3CA

Drugs & Therapeutics for Lymphangioma

About this section

Drugs for Lymphangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1PicibanilPhase 2, Phase 37
2
Octreotideapproved, investigationalPhase 222383150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
 
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate
3
EverolimusapprovedPhase 21940159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
4
Miconazoleapproved, investigational, vet_approvedPhase 2370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
5
Sirolimusapproved, investigationalPhase 2194053123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
6Vasodilator AgentsPhase 1, Phase 23543
7Sildenafil CitratePhase 1, Phase 2331171599-83-0
8Phosphodiesterase 5 InhibitorsPhase 1, Phase 2589
9Phosphodiesterase InhibitorsPhase 1, Phase 21289
10Antineoplastic Agents, HormonalPhase 25592
11Gastrointestinal AgentsPhase 28402
12Immunosuppressive AgentsPhase 213086
13Anti-Infective AgentsPhase 222062
14Antifungal AgentsPhase 23696
15Anti-Bacterial AgentsPhase 211226
16Antibiotics, AntitubercularPhase 27180
17CitrateNutraceuticalPhase 1, Phase 21160
18
Citric Acidnutraceutical, vet_approvedPhase 1, Phase 2116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
19
Marimastatapproved, investigationalPhase 14154039-60-8119031
Synonyms:
(2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(2-methylpropyl)butanediamide
(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoxy)propyl)carboyl)-2-hydroxy-5-methylhexanohydroxamic acid
(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoyl)propyl)carbamoyl)-2-hydroxy-5-methylhexanohydroxamic acid
(2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide
15039-60-8
154039-60-8
AC1L3O2N
BB 2516
BB-2516
C100342
 
C15H29N3O5
CHEBI:50662
CHEMBL279785
CID119031
D03795
DB00786
LS-45634
Marimastat
Marimastat (USAN/INN)
Marimastat [USAN]
UNII-D5EQV23TDS
20
Seleniumapproved, vet_approvedPhase 11807782-49-2
Synonyms:
Selanediide
Selen
Selenide
Selenide(2-)
Selenio
 
Selenium
Selenium elemental
Selenium ion (Se2+)
Selenium metallicum
Selenium, elemental
Sélénium
21Trace ElementsPhase 16001
22AntioxidantsPhase 13050
23Protective AgentsPhase 17443
24MicronutrientsPhase 16001
25
PancrelipaseapprovedEarly Phase 197053608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
PA
 
Pancreatic alpha-amylase precursor
Pancrelipase (amylase
lipase
protease)
26pancreatinEarly Phase 1970
27Anesthetics9596

Interventional clinical trials:

(show all 15)
idNameStatusNCT IDPhase
1Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic MalformationsCompletedNCT00010452Phase 2, Phase 3
2A Study to Evaluate Sildenafil for the Treatment of Lymphatic MalformationsCompletedNCT01290484Phase 1, Phase 2
3Sildenafil for the Treatment of Lymphatic MalformationsRecruitingNCT02335242Phase 2
4Octreotide VS Placebo in Prevention of Salivary Fistulae After Post Radiation Salvage SurgeryRecruitingNCT02437825Phase 2
5Safety and Efficacy Study of Sirolimus in Complicated Vascular AnomaliesActive, not recruitingNCT00975819Phase 2
6Phase I Drug Trial for S/E of Marimastat in Disabling Malformations When no Other Options.CompletedNCT00261391Phase 1
7Selenium in the Treatment of Complicated Lymphatic MalformationsTerminatedNCT01212965Phase 1
8Diagnosis of Hemangiomas and Vascular MalformationsCompletedNCT00577213
9Lymphatic Anomalies RegistryRecruitingNCT02399527
10AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)RecruitingNCT02250456
11Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic LesionsRecruitingNCT02494388Early Phase 1
12Registry for Vascular Anomalies Associated With CoagulopathyRecruitingNCT00576888
13Airway Vascular LesionsActive, not recruitingNCT00866827
14Imaging of Lymphatic AnomaliesEnrolling by invitationNCT02744027
15Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic DisordersEnrolling by invitationNCT00833599

Search NIH Clinical Center for Lymphangioma


Cochrane evidence based reviews: lymphangioma

Genetic Tests for Lymphangioma

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Genetic tests related to Lymphangioma:

id Genetic test Affiliating Genes
1 Lymphangioma27

Anatomical Context for Lymphangioma

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MalaCards organs/tissues related to Lymphangioma:

36
Pancreas, Tongue, Lymph node, Colon, Spleen, Breast, Endothelial

Publications for Lymphangioma

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Articles related to Lymphangioma:

(show top 50)    (show all 971)
idTitleAuthorsYear
1
An adult case of lymphangioma of the hepatoduodenal ligament mimicking a hepatic cyst. (28050777)
2017
2
A Large Hemispherical Colon Lymphangioma. (28050035)
2017
3
Lymphangioma-like classic Kaposi sarcoma. (28188608)
2017
4
Drop-Attacks Revealing a Cervical Cystic Lymphangioma. (26620381)
2016
5
Rapid growing pulmonary cavernous lymphangioma after chronic process for ten years. (27614339)
2016
6
CT Appearance of Adrenal Cystic Lymphangioma: Radiologic-Pathologic Correlation. (26700338)
2016
7
Metastatic rectal adenocarcinoma and anal squamous cell carcinoma masquerading as vulvar lymphangioma circumscriptum. (27616148)
2016
8
Lymphangioma of the ovary: etiology and management. (27401696)
2016
9
A Huge Cystic Retroperitoneal Lymphangioma Presenting with Back Pain. (27843456)
2016
10
Case report of solitary giant hepatic lymphangioma. (27212994)
2016
11
Splenic cystic lymphangioma. (27318865)
2016
12
Giant cystic lymphangioma originating from the cardia of the stomach: A case report. (27168832)
2016
13
Classical Cases of Lymphangioma - As Multiple Vesicular Eruptions. (27504428)
2016
14
Minimally Invasive Management of Complex Recurrent Lymphangioma of the Thorax and Abdomen. (27211980)
2016
15
Small intestinal and mesenteric lymphangioma in an adult: a rare cause of acute abdominal pain. (27723387)
2016
16
Giant Omental Cyst (Lymphangioma) Mimicking Ascites and Tuberculosis. (27853495)
2016
17
Diagnosis of cystic lymphangioma of the colon by endoscopic ultrasound: Biopsy is not needed! (27803907)
2016
18
Lymphangioma circumscriptum of the male genitalia. (26955596)
2016
19
Cystic Lymphangioma of Pancreas. (27065694)
2016
20
An Interesting Association of Cystic Hygroma of the Neck and Lymphangioma Causing a Paediatric Swollen Tongue. (27069707)
2016
21
Conjunctival lymphangioma in a 4-year-old girl revealed tuberous sclerosis complex. (27703871)
2016
22
Abdominal lymphangioma. (28050075)
2016
23
Adult cystic lymphangioma in the inner quadrant of the breast-Rare location for a rare disease: A case report. (26852362)
2016
24
High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience. (27329721)
2016
25
Sublingual lymphangioma that presented as a plunging ranula in a baby boy. (27068850)
2016
26
Chylopericardium presenting as cardiac tamponade secondary to mediastinal lymphangioma. (27388545)
2016
27
Laparoscopic Treatment of Intraabdominal Cystic Lymphangioma. (27452935)
2016
28
Response to OK-432 sclerotherapy in the treatment of cervical lymphangioma with submucosal extension to the airway. (27297957)
2016
29
Cystic Lymphangioma of the Pancreas: a Rare Entity. (27334312)
2016
30
Lymphangioma Circumscriptum of the Vulva. (27502262)
2016
31
An Unusual Origin of Fetal Lymphangioma Filling Right Axilla. (27134953)
2016
32
Lymphangioma Circumscriptum: A Great Mimicker. (27803540)
2016
33
A 36-Year-Old Female with Recurrent Left Sided Pleural Effusion: A Rare Case of Mediastinal Lymphangioma. (27789902)
2016
34
Vulvar verruciform xanthoma developing in acquired lymphangioma circumscriptum. (27334742)
2016
35
Mesenteric lymphangioma mimicking a cystic ovarian mass on imaging. (26833955)
2016
36
A Giant Retroperitoneal Lymphangioma: A Case Report. (27630902)
2016
37
Primary Lymphangioma of the Palatine Tonsil in a 9-Year-Old Boy: A Case Presentation and Literature Review. (27872780)
2016
38
Intradural cavernous lymphangioma of the thoracic spine: case report, technical considerations, and review of the literature. (26970599)
2016
39
Severe Pain and Edema due to a Widespread Lymphangioma: Disappearance of Symptoms and Reduction of Lesion with Spinal Cord Stimulation. (27402439)
2016
40
EP10.38: EXIT procedure in a neonate with lymphangioma diagnosed prenatally. (27647559)
2016
41
Diagnosis of perinephric retroperitoneal lymphangioma supported by contrast-enhanced ultrasound (CEUS). (27716656)
2016
42
Emergency presentation of cystic lymphangioma of the colon: A case report and literature review. (27266826)
2016
43
Retroperitoneal lymphangioma: A report of 2 cases and a review of the literature regarding the differential diagnoses of retroperitoneal cystic masses. (27123082)
2016
44
Lymphangioma-like Kaposi sarcoma. (27825645)
2016
45
Lymphangioma Circumscriptum: Good Clinical Response to Isotretinoin Therapy. (27041148)
2016
46
Giant retroperitoneal cystic lymphangioma in a patient with Eisenmenger syndrome. (26590885)
2016
47
Utility of conservative treatment in cystic lymphangioma. (27087134)
2016
48
Lymphangioma-like Kaposi Sarcoma in Transplant-Associated Iatrogenic Immunosuppression: A Case Report. (27932165)
2016
49
A rare case of acquired lymphangioma circumscriptum of the penis. (27330019)
2016
50
Volvulus of the jejunum on cystic lymphangioma: About a clinical case. (27251660)
2016

Variations for Lymphangioma

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Expression for genes affiliated with Lymphangioma

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Search GEO for disease gene expression data for Lymphangioma.

Pathways for genes affiliated with Lymphangioma

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Pathways related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 40)
idSuper pathwaysScoreTop Affiliating Genes
19.7VEGFA, VEGFC
29.3KDR, PROX1, VEGFA
3
Show member pathways
9.2FLT4, KDR, PROX1, VEGFC
4
Show member pathways
9.2EGFR, FLT4, KDR
5
Show member pathways
9.2EGFR, FLT4, KDR
69.1FLT4, PIK3CA, VEGFC
7
Show member pathways
9.1FLT4, KDR, VEGFA, VEGFC
89.0EGFR, PIK3CA
99.0EGFR, PIK3CA
109.0EGFR, PIK3CA
119.0EGFR, PIK3CA
12
Show member pathways
9.0FLT4, KDR, PIK3CA
138.9PIK3CA, VEGFA, VEGFC
148.9EGFR, FLT4, KDR, VEGFC
15
Show member pathways
8.9EGFR, FLT4, KDR, VEGFC
168.8KDR, PIK3CA, VEGFA
178.8KDR, PIK3CA, VEGFA
188.8KDR, PIK3CA, VEGFA
19
Show member pathways
8.8KDR, PIK3CA, VEGFA
20
Show member pathways
8.7EGFR, KDR, VEGFA, VEGFC
218.6EGFR, IFNA2, PIK3CA
22
Show member pathways
8.6EGFR, PIK3CA, VEGFA
238.6EGFR, PIK3CA, VEGFA
24
Show member pathways
8.4EGFR, FLT4, KDR, VEGFA, VEGFC
25
Show member pathways
8.4EGFR, FLT4, KDR, VEGFA, VEGFC
26
Show member pathways
8.4EGFR, FLT4, KDR, VEGFA, VEGFC
27
Show member pathways
8.4EGFR, FLT4, KDR, PIK3CA
28
Show member pathways
8.4EGFR, FLT4, KDR, PIK3CA
298.3EGFR, PIK3CA, VEGFA, VEGFC
30
Show member pathways
8.2FLT4, KDR, PIK3CA, VEGFA, VEGFC
31
Show member pathways
8.2FLT4, KDR, PIK3CA, VEGFA, VEGFC
32
Show member pathways
8.2EGFR, KDR, PIK3CA, VEGFA
33
Show member pathways
8.2EGFR, KDR, PIK3CA, VEGFA
348.2EGFR, KDR, PIK3CA, VEGFA
35
Show member pathways
7.9EGFR, FLT4, KDR, PIK3CA, VEGFA
36
Show member pathways
7.6EGFR, FLT4, KDR, PIK3CA, VEGFA, VEGFC
37
Show member pathways
7.6EGFR, FLT4, KDR, PIK3CA, VEGFA, VEGFC
38
Show member pathways
7.5EGFR, FLT4, IFNA2, KDR, SERPINF1, VEGFA
397.2EGFR, FLT4, IFNA2, KDR, PIK3CA, VEGFA
40
Show member pathways
7.2EGFR, FLT4, IFNA2, KDR, PIK3CA, VEGFA

GO Terms for genes affiliated with Lymphangioma

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Cellular components related to Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lamellipodiumGO:00300278.8ACTC1, PDPN, PIK3CA
2extracellular regionGO:00055768.2EGFR, FLT4, IFNA2, KDR, SERPINF1, VEGFA
3extracellular spaceGO:00056158.2ACTC1, EGFR, IFNA2, SERPINF1, VEGFA, VEGFC

Biological processes related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 38)
idNameGO IDScoreTop Affiliating Genes
1lymph vessel developmentGO:000194510.6FLT4, PROX1
2induction of positive chemotaxisGO:005093010.5VEGFA, VEGFC
3positive regulation of blood vessel endothelial cell migrationGO:004353610.5VEGFA, VEGFC
4cell migration involved in sprouting angiogenesisGO:000204210.4KDR, VEGFA
5positive regulation of protein kinase C signalingGO:009003710.4FLT4, VEGFA
6positive regulation of mast cell chemotaxisGO:006075410.4VEGFA, VEGFC
7positive regulation of neuroblast proliferationGO:000205210.4VEGFA, VEGFC
8positive regulation of protein autophosphorylationGO:003195410.4VEGFA, VEGFC
9positive regulation of cellular component movementGO:005127210.4PDPN, VEGFA
10positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwayGO:003803310.4KDR, VEGFA
11positive regulation of focal adhesion assemblyGO:005189410.3KDR, VEGFA
12positive regulation of positive chemotaxisGO:005092710.3KDR, VEGFA
13lymphangiogenesisGO:000194610.3FLT4, PDPN, PROX1
14skeletal muscle thin filament assemblyGO:003024010.2ACTC1, PROX1
15vascular endothelial growth factor signaling pathwayGO:003808410.2FLT4, KDR
16cellular response to vascular endothelial growth factor stimulusGO:003592410.1FLT4, KDR, VEGFA
17positive regulation of phosphorylationGO:004232710.1EGFR, IFNA2
18positive regulation of angiogenesisGO:004576610.1KDR, VEGFA, VEGFC
19ovulation cycleGO:004269810.1EGFR, SERPINF1
20kidney developmentGO:000182210.0PROX1, SERPINF1, VEGFA
21peptidyl-tyrosine phosphorylationGO:00181089.9EGFR, FLT4, KDR
22regulation of cell shapeGO:00083609.9KDR, PDPN, VEGFA
23positive regulation of ERK1 and ERK2 cascadeGO:00703749.9EGFR, FLT4, KDR
24protein autophosphorylationGO:00467779.8EGFR, FLT4, KDR
25positive regulation of epithelial cell proliferationGO:00506799.8EGFR, VEGFA, VEGFC
26positive regulation of cell migrationGO:00303359.8EGFR, KDR, VEGFA
27positive regulation of endothelial cell migrationGO:00105959.7FLT4, KDR, PROX1, VEGFA
28transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.7EGFR, FLT4, KDR
29lung developmentGO:00303249.5EGFR, PDPN, PROX1, VEGFA
30liver developmentGO:00018899.5EGFR, PIK3CA, PROX1
31positive regulation of endothelial cell proliferationGO:00019389.4FLT4, KDR, PROX1, VEGFA, VEGFC
32positive regulation of protein phosphorylationGO:00019349.4EGFR, FLT4, KDR, VEGFA
33vasculature developmentGO:00019449.4FLT4, PIK3CA
34angiogenesisGO:00015259.0FLT4, KDR, PIK3CA, VEGFA, VEGFC
35negative regulation of apoptotic processGO:00430669.0ACTC1, EGFR, FLT4, KDR, VEGFA
36positive regulation of cell proliferationGO:00082848.8EGFR, FLT4, KDR, PROX1, VEGFA, VEGFC
37vascular endothelial growth factor receptor signaling pathwayGO:00480108.6FLT4, KDR, PIK3CA, VEGFA, VEGFC
38multicellular organism developmentGO:00072758.3EGFR, KDR, PDPN, PROX1, SERPINF1, VEGFA

Molecular functions related to Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemoattractant activityGO:004205610.3VEGFA, VEGFC
2signal transducer, downstream of receptor, with protein tyrosine kinase activityGO:000471610.0EGFR, KDR
3vascular endothelial growth factor-activated receptor activityGO:00050219.8FLT4, KDR
4protein tyrosine kinase activityGO:00047139.7EGFR, FLT4, KDR
5transmembrane receptor protein tyrosine kinase activityGO:00047149.4EGFR, FLT4, KDR

Sources for Lymphangioma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet