MCID: LYM022
MIFTS: 53

Lymphangioma

Categories: Immune diseases, Cancer diseases

Aliases & Classifications for Lymphangioma

MalaCards integrated aliases for Lymphangioma:

Name: Lymphangioma 12 36 28 51 41 14 69
Congenital Lymphangioma 12
Benign Lymphangioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1475
ICD10 32 D18.1
ICD9CM 34 228.1
MeSH 41 D008202
NCIt 46 C8965
KEGG 36 H01471
UMLS 69 C0024221

Summaries for Lymphangioma

MalaCards based summary : Lymphangioma, also known as congenital lymphangioma, is related to lymphatic malformations and orbital lymphangioma. An important gene associated with Lymphangioma is FLT4 (Fms Related Tyrosine Kinase 4), and among its related pathways/superpathways are PEDF Induced Signaling and TGF-Beta Pathway. The drugs Picibanil and Octreotide have been mentioned in the context of this disorder. Affiliated tissues include pancreas, tongue and colon, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Lymphangioma

Diseases related to Lymphangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 221)
# Related Disease Score Top Affiliating Genes
1 lymphatic malformations 33.5 FLT4 PROX1
2 orbital lymphangioma 33.1 EGFR FLT4 PDPN
3 kaposiform hemangioendothelioma 30.5 FLT4 KDR PROX1
4 hemangioendothelioma 30.3 FLT4 KDR
5 epithelioid hemangioendothelioma 30.1 KDR VEGFA
6 hydrocele 29.8 FLT4 VEGFA
7 gorham's disease 29.7 FLT4 IFNA2 PROX1
8 hemangioma 29.5 ACTC1 FLT4 KDR PDPN PROX1 VEGFA
9 lymphangiosarcoma 29.1 FLT4 PDPN PROX1 VEGFA VEGFC
10 cystic lymphangioma 12.5
11 abdominal cystic lymphangioma 12.3
12 capillary lymphangioma 12.1
13 microcystic lymphatic malformation 12.1
14 cavernous lymphangioma 12.1
15 colonic lymphangioma 12.1
16 primary laryngeal lymphangioma 12.0
17 nuchal bleb, familial 11.8
18 cobb syndrome 11.3
19 lymphangiomatosis 11.2
20 mixed cystic lymphatic malformation 11.2
21 diffuse lymphatic malformation 11.1
22 multiple enchondromatosis, maffucci type 10.9
23 infantile myofibromatosis 10.9
24 mucinous cystadenocarcinoma of the pancreas 10.5 PDPN VEGFC
25 hobnail hemangioma 10.4 FLT4 PDPN
26 hemangioma, capillary infantile 10.4 FLT4 KDR
27 hemifacial spasm 10.4 FLT4 VEGFA
28 infiltrating angiolipoma 10.4 VEGFA VEGFC
29 mediastinitis 10.3
30 cavernous hemangioma 10.3
31 angiokeratoma circumscriptum 10.3 KDR VEGFA
32 discoid lupus erythematosus 10.3 IFNA2 PDPN
33 radiation proctitis 10.3 KDR VEGFA
34 kuhnt-junius degeneration 10.3 KDR VEGFA
35 acquired hemangioma 10.3 PDPN PROX1
36 pulmonary vein stenosis 10.3 ACTC1 KDR
37 hemangioma-thrombocytopenia syndrome 10.3
38 retiform hemangioendothelioma 10.3
39 pancreatitis 10.3
40 interstitial emphysema 10.3 FLT4 PROX1
41 congenital lymphedema 10.3 FLT4 PDPN VEGFC
42 intravascular papillary endothelial hyperplasia 10.3 ACTC1 VEGFA
43 acute hemorrhagic leukoencephalitis 10.2 KDR VEGFA
44 pyogenic granuloma 10.2 ACTC1 VEGFA
45 angiomatous meningioma 10.2 KDR VEGFA
46 cervicitis 10.2
47 coats disease 10.2 KDR VEGFA
48 carcinoid syndrome 10.2 IFNA2 VEGFA
49 spindle cell sarcoma 10.2 ACTC1 VEGFA
50 capillary hemangioma 10.2 FLT4 KDR VEGFA

Graphical network of the top 20 diseases related to Lymphangioma:



Diseases related to Lymphangioma

Symptoms & Phenotypes for Lymphangioma

MGI Mouse Phenotypes related to Lymphangioma:

43 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.21 FLT4 PDPN IFNG ACTC1 EGFR KDR
2 homeostasis/metabolism MP:0005376 10.11 EGFR KDR FLT4 ACTC1 IFNG VEGFA
3 immune system MP:0005387 10.09 KDR FLT4 PDPN IFNG EGFR SERPINF1
4 growth/size/body region MP:0005378 10.08 EGFR KDR FLT4 ACTC1 IFNG PROX1
5 digestive/alimentary MP:0005381 10.04 FLT4 PDPN IFNG EGFR SERPINF1 VEGFA
6 mortality/aging MP:0010768 9.97 EGFR KDR FLT4 ACTC1 IFNG VEGFA
7 integument MP:0010771 9.88 EGFR KDR FLT4 IFNG VEGFA PDPN
8 muscle MP:0005369 9.86 KDR FLT4 PDPN IFNG ACTC1 EGFR
9 liver/biliary system MP:0005370 9.85 KDR FLT4 IFNG EGFR VEGFA PROX1
10 normal MP:0002873 9.7 KDR FLT4 ACTC1 IFNG EGFR VEGFA
11 respiratory system MP:0005388 9.43 EGFR KDR PDPN IFNG VEGFA PROX1
12 vision/eye MP:0005391 9.1 EGFR KDR IFNG PROX1 SERPINF1 VEGFA

Drugs & Therapeutics for Lymphangioma

Drugs for Lymphangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Picibanil Phase 4,Phase 2,Phase 3
2
Octreotide Approved, Investigational Phase 2 83150-76-9 6400441 383414
3
Everolimus Approved Phase 2 159351-69-6 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 2 53123-88-9 46835353 6436030 5284616
6
Citric Acid Approved, Nutraceutical, Vet_approved Phase 1, Phase 2 77-92-9 311
7 Phosphodiesterase 5 Inhibitors Phase 1, Phase 2
8 Phosphodiesterase Inhibitors Phase 1, Phase 2
9 Sildenafil Citrate Phase 1, Phase 2 171599-83-0
10 Vasodilator Agents Phase 1, Phase 2
11 Antineoplastic Agents, Hormonal Phase 2
12 Gastrointestinal Agents Phase 2
13 Anti-Bacterial Agents Phase 2
14 Antibiotics, Antitubercular Phase 2
15 Antifungal Agents Phase 2
16 Anti-Infective Agents Phase 2
17 Immunosuppressive Agents Phase 2
18 Citrate Nutraceutical Phase 1, Phase 2
19
Marimastat Approved, Investigational Phase 1 154039-60-8 119031
20
Selenium Approved, Investigational, Vet_approved Phase 1 7782-49-2
21 Antioxidants Phase 1
22 Micronutrients Phase 1
23 Protective Agents Phase 1
24 Trace Elements Phase 1
25
Pancrelipase Approved, Investigational 53608-75-6
26 Anesthetics
27 pancreatin

Interventional clinical trials:

(show all 19)

# Name Status NCT ID Phase Drugs
1 OK432 (Picibanil) in the Treatment of Lymphatic Malformations Active, not recruiting NCT03427619 Phase 4 OK432
2 Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic Malformations Completed NCT00010452 Phase 2, Phase 3 picibanil
3 A Study to Evaluate Sildenafil for the Treatment of Lymphatic Malformations Completed NCT01290484 Phase 1, Phase 2 Sildenafil
4 Sildenafil for the Treatment of Lymphatic Malformations Recruiting NCT02335242 Phase 2 Sildenafil 20 mg tablets
5 Trial of Taselisib in Overgrowth Recruiting NCT03290092 Phase 1, Phase 2 Taselisib (GDC0032);Taselisib (GDC0032)
6 Octreotide VS Placebo in Prevention of Salivary Fistulae After Post Radiation Salvage Surgery Recruiting NCT02437825 Phase 2 octreotide
7 Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies Active, not recruiting NCT00975819 Phase 2 sirolimus
8 Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations Not yet recruiting NCT03243019 Phase 2 rapamycin
9 Phase I Drug Trial for S/E of Marimastat in Disabling Malformations When no Other Options. Completed NCT00261391 Phase 1 Marimastat
10 Selenium in the Treatment of Complicated Lymphatic Malformations Terminated NCT01212965 Phase 1 Selenium
11 Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders Unknown status NCT00833599 NIRFLI with ICG
12 Diagnosis of Hemangiomas and Vascular Malformations Completed NCT00577213
13 Lymphatic Anomalies Registry Recruiting NCT02399527
14 AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome) Recruiting NCT02250456
15 Registry for Vascular Anomalies Associated With Coagulopathy Recruiting NCT00576888
16 Airway Vascular Lesions Active, not recruiting NCT00866827
17 Imaging of Lymphatic Anomalies Enrolling by invitation NCT02744027
18 Development of a Specific Scale of Life'Quality for Children With Low-flow Vascular Malformations Not yet recruiting NCT03440827
19 Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions Terminated NCT02494388

Search NIH Clinical Center for Lymphangioma

Cochrane evidence based reviews: lymphangioma

Genetic Tests for Lymphangioma

Genetic tests related to Lymphangioma:

# Genetic test Affiliating Genes
1 Lymphangioma 28

Anatomical Context for Lymphangioma

MalaCards organs/tissues related to Lymphangioma:

38
Pancreas, Tongue, Colon, Spleen, Endothelial, Adrenal Gland, Ovary

Publications for Lymphangioma

Articles related to Lymphangioma:

(show top 50) (show all 1029)
# Title Authors Year
1
Acquired lymphangioma circumscriptum of the genitals in an individual with chronic hidradenitis suppurativa. ( 29387752 )
2018
2
A rare cause of small-bowel bleeding: haemorrhagic small-bowel lymphangioma diagnosed by antegrade double-balloon enteroscopy. ( 29351701 )
2018
3
Sirolimus-induced regression of a large orbital lymphangioma. ( 29405800 )
2018
4
Lymphangioma Circumscriptum in Vulva with Klippel-Trenaunay Syndrome. ( 29451158 )
2018
5
Lymphangioma circumscriptum of the vulva in a patient with Noonan syndrome. ( 29232041 )
2018
6
Ileal Cystic Lymphangioma presenting with Acute Appendicitis. ( 29386763 )
2018
7
Lymphangioma circumscriptum of the tongue: A case with marked hemorrhagic component. ( 29315723 )
2018
8
Percutaneous therapy of a mediastinal lymphangioma with fibrin glue: case report with clinical success after 4A years. ( 29361923 )
2018
9
Mediastinal lymphangioma in an adult. ( 29397964 )
2018
10
Surgery of multiple lymphangioma in small bowel: a rare case report of chronic gastrointestinal bleeding. ( 29333427 )
2018
11
Lymphangioma circumscriptum der Vulva bei einer Patientin mit Noonan-Syndrom. ( 29314699 )
2018
12
Transient Reactive Eruptive Lymphangiectasia Following Partial Vulvectomy for Chronic Acquired Lymphangioma. ( 28859749 )
2017
13
An acute presentation of pediatric mesenteric lymphangioma: a case report and literature overview. ( 28927352 )
2017
14
Orbital Lymphangioma: Characteristics and Treatment Outcomes of 12 Cases. ( 28534344 )
2017
15
Cystic Lymphangioma of the Colon: Endoscopic Removal beyond the Frontiers of Size. ( 28512390 )
2017
16
Lymphangioma ( 29261940 )
2017
17
Cystic lymphangioma of spleen in adults. ( 28122799 )
2017
18
Acquired progressive lymphangioma: Case report with partial response to imiquimod 5% cream. ( 28940760 )
2017
19
Abdominal cystic lymphangioma in a term newborn: A case report and update of new treatments. ( 28225486 )
2017
20
A Large Hemispherical Colon Lymphangioma. ( 28050035 )
2017
21
Treatment of Tongue Lymphangioma with Intralesional Combination Injection of Steroid, Bleomycin and Bevacizumab. ( 28913305 )
2017
22
A Rare Cause of Dyspnea: Cervicothoracic Cystic Lymphangioma. ( 28872508 )
2017
23
Dermoscopy of lymphangioma circumscriptum: A morphological study of 45 cases. ( 28752523 )
2017
24
Incidental finding of (131)I uptake in mesenteric cystic lymphangioma on post-therapy (131)I SPECT/CT imaging. ( 28215398 )
2017
25
Lymphangiosarcoma of the hip arising in a congenital non-irradiated lymphangioma. ( 29068520 )
2017
26
An adult case of lymphangioma of the hepatoduodenal ligament mimicking a hepatic cyst. ( 28050777 )
2017
27
Mixed Lymphangioma and Cavernous Hemangioma Within the Ulnar Nerve: A Case Report. ( 28391718 )
2017
28
Rare Case of Pancreatic Cystic Lymphangioma. ( 29151529 )
2017
29
Natural Course of Fetal Axillary Lymphangioma Based on Prenatal Ultrasound Studies. ( 29119576 )
2017
30
Large Omental Cystic Lymphangioma Masquerading as Mucinous Ovarian Neoplasia in an 8-Year-Old Premenarchal Girl: The Findings from Diagnostic Imaging and Laparoscopic-Assisted Excision. ( 28629796 )
2017
31
Recurring Giant Mediastinal Cystic Lymphangioma. ( 28363031 )
2017
32
WITHDRAWN: Role of Intralesional Bleomycin in Orbital Lymphangioma: A Prospective Study. ( 28579136 )
2017
33
Management of a large cystic lymphangioma causing intestinal obstruction. ( 28477401 )
2017
34
Gastrointestinal: Giant mesenteric cystic lymphangioma. ( 28221691 )
2017
35
Cystic Lymphangioma of the Chest Wall in a 5-Year-Old Male Patient: A Rare and Atypical Localization-A Case Report and Comprehensive Review of the Literature. ( 29201481 )
2017
36
Fibroepithelial polyp of the vulva accompanied by lymphangioma circumscriptum. ( 28791276 )
2017
37
Axillary lymphangioma in an asymptomatic adult female. ( 28877380 )
2017
38
Small bowel volvulus in an adult with mesenteric lymphangioma and ascariasis. ( 28266164 )
2017
39
Lymphangioma secondary to irradiation after mastectomy. ( 29186257 )
2017
40
Imaging findings of axillary cystic lymphangioma in adult. ( 28735807 )
2017
41
Splenic lymphangioma in an adult. ( 29114705 )
2017
42
Pancreatic Lymphangioma: A Diagnostic and Treatment Dilemma. ( 28738930 )
2017
43
Vulvar lymphangioma circumscriptum: comparison of primary and acquired forms in a cohort of 57 patients. ( 28758249 )
2017
44
A prospective study of the role of intralesional bleomycin in orbital lymphangioma. ( 28300684 )
2017
45
Cystic Lymphangioma of the Mesenteric Root in an Adolescent, an Operative Challenge. ( 28958247 )
2017
46
Cystic lymphangioma of the lesser omentum in a pregnant woman: a case report and review of the literature. ( 28976139 )
2017
47
Dermoscopy of cutaneous lymphangioma circumscriptum. ( 28515992 )
2017
48
Microbubbles in macrocysts - Contrast-enhanced ultrasound assisted sclerosant therapy of a congenital macrocystic lymphangioma: a case report. ( 28683719 )
2017
49
Peri-Punctal Lymphangioma Treated With Bleomycin. ( 28863118 )
2017
50
Small Intestinal Lymphangioma Presenting as an Acute Abdomen with Relevant Review of Literature. ( 28764241 )
2017

Variations for Lymphangioma

Expression for Lymphangioma

Search GEO for disease gene expression data for Lymphangioma.

Pathways for Lymphangioma

Pathways related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 32)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.39 EGFR FLT4 IFNA2 IFNG KDR SERPINF1
2
Show member pathways
13.33 EGFR FLT4 IFNA2 IFNG KDR VEGFA
3
Show member pathways
13.09 EGFR FLT4 KDR VEGFA VEGFC
4
Show member pathways
12.73 EGFR FLT4 IFNA2 KDR VEGFA VEGFC
5
Show member pathways
12.72 EGFR FLT4 KDR VEGFA VEGFC
6 12.6 EGFR FLT4 KDR VEGFA VEGFC
7
Show member pathways
12.53 EGFR FLT4 KDR VEGFA VEGFC
8
Show member pathways
12.5 EGFR FLT4 KDR VEGFC
9 12.46 EGFR FLT4 IFNA2 IFNG VEGFA VEGFC
10
Show member pathways
12.44 FLT4 KDR VEGFA VEGFC
11
Show member pathways
12.19 EGFR IFNA2 IFNG
12
Show member pathways
12.15 EGFR FLT4 KDR VEGFA VEGFC
13 12.13 EGFR KDR VEGFA
14
Show member pathways
12.08 EGFR KDR VEGFA VEGFC
15 12.02 EGFR IFNG VEGFA
16 11.94 EGFR FLT4 KDR VEGFC
17
Show member pathways
11.93 EGFR FLT4 KDR VEGFA VEGFC
18 11.92 IFNG KDR VEGFA
19 11.89 KDR PROX1 VEGFA
20 11.75 EGFR IFNG VEGFA
21 11.69 EGFR IFNA2 IFNG
22
Show member pathways
11.67 FLT4 KDR VEGFA VEGFC
23 11.57 FLT4 KDR PROX1 VEGFC
24
Show member pathways
11.31 EGFR KDR VEGFA
25 11.19 KDR VEGFA
26 11.01 KDR VEGFA
27 10.98 FLT4 VEGFC
28 10.92 IFNG VEGFA
29 10.88 EGFR FLT4 KDR VEGFA
30 10.85 EGFR FLT4 KDR VEGFC
31 10.52 VEGFA VEGFC
32
Show member pathways
10.13 FLT4 KDR VEGFA VEGFC

GO Terms for Lymphangioma

Cellular components related to Lymphangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 ACTC1 EGFR IFNA2 IFNG SERPINF1 VEGFA
2 extracellular region GO:0005576 9.23 EGFR FLT4 IFNA2 IFNG KDR SERPINF1

Biological processes related to Lymphangioma according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 regulation of receptor activity GO:0010469 9.96 IFNA2 IFNG VEGFA VEGFC
2 negative regulation of apoptotic process GO:0043066 9.91 ACTC1 EGFR FLT4 KDR PDPN VEGFA
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.86 EGFR FLT4 KDR
4 protein autophosphorylation GO:0046777 9.86 EGFR FLT4 KDR
5 angiogenesis GO:0001525 9.86 FLT4 KDR VEGFA VEGFC
6 peptidyl-tyrosine phosphorylation GO:0018108 9.85 EGFR FLT4 KDR
7 regulation of cell shape GO:0008360 9.83 KDR PDPN VEGFA
8 positive regulation of angiogenesis GO:0045766 9.83 KDR VEGFA VEGFC
9 positive regulation of cell migration GO:0030335 9.83 EGFR KDR PDPN VEGFA
10 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.82 EGFR FLT4 KDR
11 kidney development GO:0001822 9.81 PROX1 SERPINF1 VEGFA
12 negative regulation of gene expression GO:0010629 9.8 IFNA2 IFNG KDR SERPINF1 VEGFA
13 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.77 IFNA2 IFNG VEGFA
14 lung development GO:0030324 9.76 EGFR PDPN PROX1 VEGFA
15 positive regulation of epithelial cell proliferation GO:0050679 9.74 EGFR VEGFA VEGFC
16 cellular response to dexamethasone stimulus GO:0071549 9.69 EGFR SERPINF1
17 positive regulation of phosphorylation GO:0042327 9.69 EGFR IFNA2
18 positive regulation of blood vessel endothelial cell migration GO:0043536 9.69 KDR VEGFA VEGFC
19 positive regulation of focal adhesion assembly GO:0051894 9.68 KDR VEGFA
20 positive regulation of protein complex assembly GO:0031334 9.67 IFNG VEGFA
21 positive regulation of protein autophosphorylation GO:0031954 9.67 VEGFA VEGFC
22 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.67 IFNA2 IFNG
23 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.67 FLT4 KDR VEGFA
24 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.67 FLT4 KDR VEGFA VEGFC
25 positive regulation of neuroblast proliferation GO:0002052 9.66 VEGFA VEGFC
26 cell migration involved in sprouting angiogenesis GO:0002042 9.65 KDR VEGFA
27 positive regulation of protein phosphorylation GO:0001934 9.65 EGFR FLT4 IFNG KDR VEGFA
28 induction of positive chemotaxis GO:0050930 9.64 VEGFA VEGFC
29 positive regulation of positive chemotaxis GO:0050927 9.63 KDR VEGFA
30 lymph vessel development GO:0001945 9.62 FLT4 PROX1
31 positive regulation of cellular component movement GO:0051272 9.62 PDPN VEGFA
32 ovulation cycle GO:0042698 9.61 EGFR SERPINF1
33 positive regulation of protein kinase C signaling GO:0090037 9.61 FLT4 VEGFA
34 vascular endothelial growth factor signaling pathway GO:0038084 9.6 FLT4 KDR
35 skeletal muscle thin filament assembly GO:0030240 9.58 ACTC1 PROX1
36 positive regulation of mast cell chemotaxis GO:0060754 9.58 VEGFA VEGFC
37 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.55 KDR VEGFA
38 actin-mediated cell contraction GO:0070252 9.54 ACTC1 PDPN
39 lymphangiogenesis GO:0001946 9.5 FLT4 PDPN PROX1
40 positive regulation of cell proliferation GO:0008284 9.5 EGFR FLT4 IFNG KDR PROX1 VEGFA
41 positive regulation of endothelial cell migration GO:0010595 9.46 FLT4 KDR PROX1 VEGFA
42 positive regulation of endothelial cell proliferation GO:0001938 9.02 FLT4 KDR PROX1 VEGFA VEGFC
43 multicellular organism development GO:0007275 10.02 EGFR KDR PDPN PROX1 SERPINF1 VEGFA

Molecular functions related to Lymphangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.54 IFNA2 IFNG VEGFA
2 protein tyrosine kinase activity GO:0004713 9.43 EGFR FLT4 KDR
3 chemoattractant activity GO:0042056 9.32 VEGFA VEGFC
4 signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.16 EGFR KDR
5 vascular endothelial growth factor-activated receptor activity GO:0005021 8.96 FLT4 KDR
6 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.8 EGFR FLT4 KDR

Sources for Lymphangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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