MCID: LYM014
MIFTS: 35

Lymphangitis malady

Categories: Cardiovascular diseases, Immune diseases

Aliases & Classifications for Lymphangitis

Summaries for Lymphangitis

Disease Ontology : 12 A lymphatic system disease that is characterized by inflammation of the lymphatic channels which occurs as a result of infection at a site distal to the channel. It is caused by Streptococcus pyogenes (Group A strep) or Staphylococcus aureus. Lymphangitis is also sometimes called blood poisoning.

MalaCards based summary : Lymphangitis is related to lymphogranuloma venereum and melioidosis. An important gene associated with Lymphangitis is HCFC1 (Host Cell Factor C1), and among its related pathways/superpathways are Wnt / Hedgehog / Notch and Amino acid synthesis and interconversion (transamination). The drugs Amoxicillin and Clavulanic Acid have been mentioned in the context of this disorder. Affiliated tissues include lung, breast and testes.

Wikipedia : 71 Lymphangitis is an inflammation or an infection of the lymphatic channels that occurs as a result of... more...

Related Diseases for Lymphangitis

Diseases related to Lymphangitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
id Related Disease Score Top Affiliating Genes
1 lymphogranuloma venereum 11.1
2 melioidosis 10.8
3 filarial elephantiasis 10.8
4 milker's nodule 10.8
5 histoplasmosis 10.0
6 elephantiasis 10.0
7 breast cancer 9.8
8 lymphedema 9.8
9 adenocarcinoma 9.8
10 cellulitis 9.7
11 lung cancer 9.6
12 pulmonary hypertension 9.6
13 crohn's disease 9.6
14 gastric cancer 9.6
15 thrombosis 9.6
16 filariasis 9.6
17 respiratory failure 9.6
18 erysipelas 9.6
19 sporotrichosis 9.6
20 lymphadenitis 9.6
21 dermatitis 9.6
22 tuberculosis 9.6
23 pancreatitis 9.6
24 eccrine porocarcinoma 9.6
25 peritonitis 9.6
26 herpes simplex 9.6
27 duodenitis 9.6
28 choledochal cyst 9.6
29 rheumatoid arthritis 9.5
30 bacteremia 9.5
31 renal cell carcinoma 9.5
32 acute kidney failure 9.5
33 arthritis 9.5
34 leukemia 9.5
35 osteoarthritis 9.5
36 pulmonary emphysema 9.5
37 thrombocytopenia 9.5
38 atrioventricular block 9.5
39 osteomyelitis 9.5
40 dermatomyositis 9.5
41 pleurisy 9.5
42 spotted fever 9.5
43 chlamydia 9.5
44 paracoccidioidomycosis 9.5
45 glanders 9.5
46 obstructive jaundice 9.5
47 hypothyroidism 9.5
48 pneumothorax 9.5
49 squamous cell carcinoma 9.5
50 pericarditis 9.5

Comorbidity relations with Lymphangitis via Phenotypic Disease Network (PDN):


Peripheral Vascular Disease

Graphical network of the top 20 diseases related to Lymphangitis:



Diseases related to Lymphangitis

Symptoms & Phenotypes for Lymphangitis

Drugs & Therapeutics for Lymphangitis

Drugs for Lymphangitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved 26787-78-0 33613 2171
2 Clavulanic Acid
3 Amoxicillin-Potassium Clavulanate Combination
4 Anti-Bacterial Agents
5 beta-Lactamase Inhibitors
6 Anti-Infective Agents

Interventional clinical trials:


id Name Status NCT ID Phase
1 Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media) Completed NCT01406275

Search NIH Clinical Center for Lymphangitis

Cochrane evidence based reviews: lymphangitis

Genetic Tests for Lymphangitis

Anatomical Context for Lymphangitis

MalaCards organs/tissues related to Lymphangitis:

39
Lung, Breast, Testes, Cervix, Skin, Trachea, Colon

Publications for Lymphangitis

Articles related to Lymphangitis:

(show top 50) (show all 229)
id Title Authors Year
1
Lymphangitis from Scolopendra heros Envenomation: The Texas Redheaded Centipede. ( 28089338 )
2017
2
Focal intestinal lipogranulomatous lymphangitis in 10 dogs. ( 27359251 )
2016
3
IMAGES IN CLINICAL MEDICINE. Lymphangitis on the Abdomen. ( 27682055 )
2016
4
Allergic lymphangitis. ( 27903496 )
2016
5
Pulmonary lymphangitis carcinomatosis- A case report. ( 27728575 )
2016
6
Development and Evaluation of a Molecular Diagnostic Method for Rapid Detection of Histoplasma capsulatum var. farciminosum, the Causative Agent of Epizootic Lymphangitis, in Equine Clinical Samples. ( 27707938 )
2016
7
Case with cellulitis, lymphangitis and subcutaneous nodule suspected due to Rickettsia japonica carrying tick bite. ( 27786374 )
2016
8
Unusual cause of lymphangitis in a 2-year-old boy. ( 27181743 )
2016
9
Nonbacterial Causes of Lymphangitis with Streaking. ( 28076265 )
2016
10
Lymphangitis occurring after intralesional Candida antigen injection for verruca vulgaris. ( 27617613 )
2016
11
Blue Lymphangitis of the Breast after Breast Cancer: Case Report. ( 27914118 )
2016
12
Folliculotropic Cutaneous Metastases and Lymphangitis Carcinomatosa: When Cutaneous Metastases of Breast Carcinoma Are Mistaken for Cutaneous Infections. ( 27477179 )
2016
13
Mediterranean spotted fever with lymphangitis occurring from a tick bite lesion. A case in Spain. ( 26173583 )
2015
14
Participatory appraisal of the impact of epizootic lymphangitis in Ethiopia. ( 25980831 )
2015
15
Images in clinical medicine. Acute lymphangitis. ( 25671257 )
2015
16
Hypereosinophilic Pulmonary Carcinomatous Lymphangitis Mimicking Acute Eosinophilic Pneumonia. ( 26371814 )
2015
17
Staphylococcus aureus sporotrichoid lymphangitis without bacteremia in a transplant recipient. ( 25582343 )
2015
18
Creeping lymphangitis. ( 26463674 )
2015
19
Reply to "Inclusion of Lymphangitis as a Descriptor in the New TNM Staging of Lung Cancer: Filling Up the Blank Spaces". ( 26709486 )
2015
20
Emphysematous Eosinophilic Lymphangitis in the Ruminal Submucosa of Cattle. ( 25710949 )
2015
21
Nonvenereal sclerosing lymphangitis of the penis. ( 26228831 )
2015
22
Inclusion of Lymphangitis as a Descriptor in the New TNM Staging of Lung Cancer: Filling Up the Blank Spaces. ( 26709485 )
2015
23
Rare diagnosis of nodular lymphangitis caused by Mycobacterium marinum: MDCT imaging findings. ( 24778804 )
2014
24
Focal intestinal lipogranulomatous lymphangitis in 6 dogs (2008-2011). ( 24205954 )
2014
25
Sclerosing lymphangitis of penis - literature review and report of 2 cases. ( 25046462 )
2014
26
Clinicopathological features and outcomes of gastric cancer patients with pulmonary lymphangitis carcinomatosa. ( 25057093 )
2014
27
Duodenal lymphangitis carcinomatosa: A rare case. ( 27186245 )
2014
28
Granulomatous typhlocolitis, lymphangitis, and lymphadenitis in a horse infected with Listeria monocytogenes, Salmonella Typhimurium, and cyathostomes. ( 22688587 )
2013
29
Metastatic Crohn's disease accompanying granulomatous vasculitis and lymphangitis in the vulva. ( 24133609 )
2013
30
First case report of Nocardia veterana causing nodular lymphangitis in an immunocompromised host. ( 23566257 )
2013
31
Acute kidney failure with renal carcinomatous lymphangitis secondary to advanced colon cancer. ( 23903432 )
2013
32
Cutaneous lymphangitis carcinomatosa in a patient with lung adenocarcinoma: case report and literature review. ( 23164553 )
2013
33
Superficial lymphangitis after insect bite. ( 23415620 )
2013
34
Carcinomatous lymphangitis in lymphoepithelial carcinoma of the parotid. ( 23680220 )
2013
35
Large or persistent lymphocyst increases the risk of lymphedema, lymphangitis, and deep vein thrombosis after retroperitoneal lymphadenectomy for gynecologic malignancy. ( 23455541 )
2013
36
Rapidly lethal dermatomyositis associated with cutaneous lymphangitis carcinomatosa. ( 23761617 )
2013
37
Education and imaging. Gastrointestinal: Symmetric lymphangitis of lower limbs originating from a perianal abscess. ( 24308045 )
2013
38
Granulomatous lymphangitis. ( 23773564 )
2013
39
Eccrine porocarcinoma with carcinomatous lymphangitis in a patient with history of arsenic exposure: a case report. ( 22108500 )
2012
40
Gastric adenocarcinoma associated with lymphangitis carcinomatosa, adrenal metastasis with ectopic ACTH syndrome and malignant common bile duct stricture. ( 22560823 )
2012
41
Mesenteric lymphangitis and sepsis due to RTX toxin-producing Actinobacillus spp in 2 foals with hypothyroidism-dysmaturity syndrome. ( 21460119 )
2012
42
Evaluation of berries of Phytolacca dodecandra for growth inhibition of Histoplasma capsulatum var. farciminosum and treatment of cases of epizootic lymphangitis in Ethiopia. ( 23569960 )
2012
43
Carcinomatosis lymphangitis and pleurisy after allo-SCT in two patients with secondary leukemia after breast cancer. ( 21383684 )
2012
44
Cutaneous lymphangitis carcinomatosis metastasis of extra-ovarian primary peritoneal carcinoma. ( 22949038 )
2012
45
Successful treatment of nodular lymphangitis due to Mycobacterium chelonae in two immunosuppressed patients. ( 21426874 )
2011
46
Acute superficial lymphangitis following pigeon mite bite. ( 22798101 )
2010
47
Lymphangitis carcinomatosa: report of a case and review of literature. ( 22693377 )
2010
48
Cancer-related secondary lymphoedema due to cutaneous lymphangitis carcinomatosa: clinical presentations and review of literature. ( 20030691 )
2010
49
Acute generalized exanthematous pustulosis with lymphangitis triggered by a spider bite. ( 20001785 )
2010
50
Nodular lymphangitis: Report of a case with presentation of a diagnostic paradigm. ( 20875322 )
2010

Variations for Lymphangitis

Expression for Lymphangitis

Search GEO for disease gene expression data for Lymphangitis.

Pathways for Lymphangitis

Pathways related to Lymphangitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.51 CSNK1D FOXD3
2
Show member pathways
10.77 GPT GPT2
3 10.5 GPT GPT2
4
Show member pathways
10.13 GPT GPT2

GO Terms for Lymphangitis

Biological processes related to Lymphangitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular amino acid biosynthetic process GO:0008652 9.16 GPT GPT2
2 biosynthetic process GO:0009058 8.96 GPT GPT2
3 L-alanine catabolic process GO:0042853 8.62 GPT GPT2

Molecular functions related to Lymphangitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 pyridoxal phosphate binding GO:0030170 9.16 GPT GPT2
2 transaminase activity GO:0008483 8.96 GPT GPT2
3 L-alanine:2-oxoglutarate aminotransferase activity GO:0004021 8.62 GPT GPT2

Sources for Lymphangitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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