MCID: LYM014
MIFTS: 46

Lymphangitis malady

Cardiovascular diseases, Immune diseases categories

Summaries for Lymphangitis

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A disease of lympoid system that results in inflammation of the lymphatic channels which occurs as a result of infection at a site distal to the channel. it is caused by streptococcus pyogenes (group a strep) or staphylococcus aureus. lymphangitis is also sometimes called blood poisoning.

MalaCards: Lymphangitis, also known as lymphangitis nos, is related to breast cancer and lung cancer. An important gene associated with Lymphangitis is CILP (cartilage intermediate layer protein, nucleotide pyrophosphohydrolase), and among its related pathways are Gastric cancer network 2 and Platelet degranulation . The compounds fosinopril and repaglinide have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and breast, and related mouse phenotype tumorigenesis.

Wikipedia:63 Lymphangitis is an inflammation or an infection of the lymphatic channels that occurs as a result of... more...

Aliases & Classifications for Lymphangitis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 39NCIt, 25ICD10
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Related Diseases for Lymphangitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Lymphangitis:



Diseases related to lymphangitis

Clinical Features for Lymphangitis

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Drugs & Therapeutics for Lymphangitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Lymphangitis

Drug clinical trials:

Search ClinicalTrials for Lymphangitis

Search NIH Clinical Center for Lymphangitis

Search CenterWatch for Lymphangitis

Genetic Tests for Lymphangitis

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Anatomical Context for Lymphangitis

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32MalaCards
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MalaCards organs/tissues related to Lymphangitis:

32
Lung, Testes, Breast, Cervix, Skin, Lymph node, Colon, Kidney, Trachea

Animal Models for Lymphangitis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Lymphangitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.5TP53, ALB, SERPINE1, EGFR

Publications for Lymphangitis

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50PubMed
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Articles related to Lymphangitis:

(show top 50)    (show all 203)
idTitleAuthorsYear
1
Superficial lymphangitis after insect bite. (23415620)
2013
2
Education and imaging. Gastrointestinal: Symmetric lymphangitis of lower limbs originating from a perianal abscess. (24308045)
2013
3
Eccrine porocarcinoma with carcinomatous lymphangitis in a patient with history of arsenic exposure: a case report. (22108500)
2012
4
Mesenteric lymphangitis and sepsis due to RTX toxin-producing Actinobacillus spp in 2 foals with hypothyroidism-dysmaturity syndrome. (21460119)
2012
5
Successful treatment of nodular lymphangitis due to Mycobacterium chelonae in two immunosuppressed patients. (21426874)
2011
6
Nodular lymphangitis: Report of a case with presentation of a diagnostic paradigm. (20875322)
2010
7
Lymphangitis carcinomatosa: report of a case and review of literature. (22693377)
2010
8
Nonvenereal sclerosing lymphangitis of the penis. (20016439)
2009
9
Lymphangitis carcinomatosa as an unusual presentation of renal cell carcinoma: a case report. (18218137)
2008
10
A case of Mycobacterium avium complex infection in an immunocompetent man presenting with pericarditis and an HRCT pattern of lymphangitis. (18471684)
2008
11
Histofarcin test for the diagnosis of epizootic lymphangitis in Ethiopia: development, optimisation, and validation in the field. (16490721)
2006
12
Duodenal lymphangitis carcinomatosa: endoscopic characteristics and clinical significance. (16706816)
2006
13
Epidemiology of equine histoplasmosis (epizootic lymphangitis) in carthorses in Ethiopia. (16772141)
2006
14
The importance of histology in the evaluation of pulmonary transplantation: carcinomatous lymphangitis. (15786013)
2005
15
Lymphangitis after self-administration of lipopolysaccharide. (15745993)
2005
16
Gloves and socks lymphangitis associated with acute parvovirus B19 infection. (12657026)
2003
17
Superficial lymphangitis with interface dermatitis occurring shortly after a minor injury: possible involvement of a bacterial infection and contact allergens. (11701974)
2001
18
Carcinomatous lymphangitis mimicking pulmonary thromboembolism. (11446506)
2001
19
Cutaneous histiocytic lymphangitis: an unusual manifestation of rheumatoid arthritis. (10812704)
2000
20
Phytophotodermatitis mimicking superficial lymphangitis. (10809893)
2000
21
Lymphangitis as a complication of intralesional bleomycin therapy. (9704855)
1998
22
Obstructive jaundice caused by lymphangitis carcinomatosa of bile duct wall from gastric carcinoma. (9516509)
1998
23
Bancroftian lymphangitis in northeastern Brazil: a histopathological study of 17 cases. (1560478)
1992
24
Lymphangitis after tuberculin test. (2044739)
1991
25
A case of sclerosing lymphangitis of the lip. (2329223)
1990
26
Gabriel Andral (1797-1876) and the first reports of lymphangitis carcinomatosa. (2674433)
1989
27
Prolonged remission of lymphangitis carcinomatosis from breast cancer. (2519566)
1989
28
Prolonged remission of lymphangitis carcinomatosis from breast cancer. (2835073)
1987
29
Lymphangitis after tuberculin tests. (6432215)
1984
30
Lymphangitis and scarlet fever after finger injury from a computer game. (6512753)
1984
31
Herpetic lymphangitis in a student population. (6288639)
1982
32
Unusual complication of allergic contact dermatitis of the hands -- recurrent lymphangitis and persistent lymphoedema. (7105698)
1982
33
Surgical management of persistent, symptomatic nonvenereal sclerosing lymphangitis of the penis. (7087006)
1982
34
Lymphangitis carcinomatosa in a case of carcinoma of the cervix. (7460411)
1980
35
Non-venereal sclerosing lymphangitis of the penis following herpes progenitalis. (871405)
1977
36
Erysipelas: facial lymphangitis. (265381)
1977
37
Nonvenereal sclerosing lymphangitis of the penis. (1147635)
1975
38
Non-venereal sclerosing lymphangitis of the penis. A clinicopathologic treatise. (4195869)
1970
39
Researches on elephantiasis nostras and elephantiasis tropica with special regard to their initial stage of recurring lymphangitis (lymphangitis recurrens elephantogenica). (5377701)
1969
40
Lymphangitis reticularis tuberculosa. (5716377)
1968
41
A note on an outbreak of epizootic lymphangitis in equines. (5949471)
1966
42
CASE OF CARDIAC LYMPHANGITIS WITH ATRIOVENTRICULAR BLOCK. (14305351)
1965
43
Prophylaxis of recurrent lymphangitis complicating lymphedema: preliminary observations. (13863624)
1962
44
Endemic lymphangitis in French Guiana and its relation to W. ban-crofti filariasis. (13772181)
1960
45
Recurrent herpes simplex infections of upper extremities with lymphangitis; report of three cases with virus studies in two. (13007176)
1953
46
Chronic lymphangitis and chronic recurrent angioneurotic edema of the face. (21000226)
1946
47
Chronic lymphangitis. (21000214)
1946
48
Thromboangitis, phlebitis and lymphangitis of the spermatic cord in relation to lymphogranuloma venereum. (21002192)
1946
49
Recurrent Lymphangitis: Report of A Case with Unusual Features. (18746062)
1941
50
Sporothrix and Epizootic Lymphangitis. (19971963)
1910

Genetic Variations for Lymphangitis

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Expression for genes affiliated with Lymphangitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Lymphangitis

Search GEO for disease gene expression data for Lymphangitis.

Pathways for genes affiliated with Lymphangitis

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37NCBI BioSystems Database, 53Reactome, 29KEGG
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Pathways related to Lymphangitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4TP53, EGFR
2
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9.2ALB, SERPINE1, VEGFC
39.0TP53, VEGFC, EGFR
49.0TP53, SERPINE1, EGFR
5
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8.9SERPINE1, ALB, TP53

Compounds for genes affiliated with Lymphangitis

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44Novoseek, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 28IUPHAR, 24HMDB
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Compounds related to Lymphangitis according to GeneCards/GeneDecks:

(show all 33)
idCompoundScoreTop Affiliating Genes
1fosinopril44 1110.9SERPINE1, ALB
2repaglinide44 49 1111.9ALB, SERPINE1
3ramipril44 1110.9ALB, SERPINE1
4p00001449.9VEGFC, SERPINE1
5valsartan44 59 28 1112.9SERPINE1, ALB
6perindopril44 49 1111.9ALB, SERPINE1
7irbesartan44 28 49 1112.9ALB, SERPINE1
8Vandetanib119.9ALB, EGFR
9piroxicam44 1110.9ALB, EGFR
10hydrochlorothiazide44 49 28 11 2413.9SERPINE1, ALB
11candesartan44 28 1111.8ALB, SERPINE1
12enalapril44 49 1111.8SERPINE1, ALB
13spironolactone49 44 59 28 1113.8ALB, SERPINE1
14amlodipine44 49 11 2412.8ALB, SERPINE1
15diisopropylfluorophosphate449.7SERPINE1, ALB
16temozolomide44 1110.7EGFR, TP53
17taxane449.7TP53, EGFR
18sn 3844 5910.7TP53, EGFR
19bcnu449.7TP53, EGFR
20fluorouracil49 1110.6ALB, TP53
21erlotinib44 49 1111.6ALB, EGFR
22sulindac44 1110.5TP53, ALB
23suberoylanilide hydroxamic acid449.4TP53, EGFR
24irinotecan44 49 1111.3EGFR, ALB, TP53
25sb 20358044 5910.2EGFR, SERPINE1, TP53
26pd 98,059449.1SERPINE1, VEGFC, EGFR
27topotecan44 1110.1TP53, EGFR
28testosterone44 59 11 2412.1EGFR, VEGFC, SERPINE1, ALB
29ly294002449.0TP53, SERPINE1, VEGFC, EGFR
30progesterone44 59 28 11 2413.0EGFR, VEGFC, SERPINE1, TP53
31vegf449.0TP53, SERPINE1, VEGFC, EGFR
32estrogen448.7EGFR, VEGFC, SERPINE1, TP53
33retinoic acid44 249.6EGFR, VEGFC, SERPINE1, TP53

GO Terms for genes affiliated with Lymphangitis

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16Gene Ontology
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Cellular components related to Lymphangitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:0310938.9ALB, SERPINE1, VEGFC
2extracellular spaceGO:0056158.4ALB, SERPINE1, VEGFC, CILP, EGFR

Biological processes related to Lymphangitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:0301689.2ALB, SERPINE1, VEGFC
2platelet degranulationGO:0025769.1ALB, SERPINE1, VEGFC
3blood coagulationGO:0075968.2VEGFC, SERPINE1, ALB, TP53

Molecular functions related to Lymphangitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chaperone bindingGO:0510879.3TP53, ALB
2enzyme bindingGO:0198998.6TP53, ALB, EGFR

Products for genes affiliated with Lymphangitis

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  • Antibodies
  • Proteins
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  • Antibodies

Sources for Lymphangitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet