MCID: LYM040
MIFTS: 53

Lymphoblastic Lymphoma malady

Categories: Rare diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Lymphoblastic Lymphoma

Aliases & Descriptions for Lymphoblastic Lymphoma:

Name: Lymphoblastic Lymphoma 38 12 50 14
Precursor Cell Lymphoblastic Leukemia Lymphoma 69
Precursor Cell Lymphoblastic Lymphoma 69
Lymphoma, Lymphoblastic 50
Lymphoma Lymphoblastic 52

Classifications:



External Ids:

Disease Ontology 12 DOID:0080147
ICD10 33 C83.5

Summaries for Lymphoblastic Lymphoma

Disease Ontology : 12 A lymphoma that has material basis in immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage and located in primarily lymph nodes or located in extranodal sites.

MalaCards based summary : Lymphoblastic Lymphoma, also known as precursor cell lymphoblastic leukemia lymphoma, is related to acute leukemia and acute lymphocytic leukemia. An important gene associated with Lymphoblastic Lymphoma is PTPRC (Protein Tyrosine Phosphatase, Receptor Type C), and among its related pathways/superpathways are NF-kappaB Signaling and Neural Crest Differentiation. The drugs Arranon and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include t cells, b cells and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and hematopoietic system

Related Diseases for Lymphoblastic Lymphoma

Diseases related to Lymphoblastic Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
id Related Disease Score Top Affiliating Genes
1 acute leukemia 29.7 DNTT KMT2A MPO
2 acute lymphocytic leukemia 29.2 DNTT KMT2A MPO TAL1
3 neurofibromatosis 29.0 DNTT KMT2A MPO PTPRC
4 t-cell childhood lymphoblastic lymphoma 12.2
5 precursor t-lymphoblastic lymphoma/leukemia 12.1
6 precursor b lymphoblastic lymphoma/leukemia 12.0
7 precursor lymphoblastic lymphoma/leukemia 11.9
8 childhood precursor t-lymphoblastic lymphoma/leukemia 11.9
9 precursor t-lymphoblastic lymphoma/leukemia refractory 11.9
10 chromosome 8p11 myeloproliferative syndrome 11.0
11 acute t cell leukemia 10.9
12 lymphoma 10.9
13 leukemia 10.5
14 lymphoblastic leukemia 10.4
15 ethmoid sinus inverted papilloma 10.2 MME PTPRC
16 coloboma of eyelid 10.2 KMT2A MME
17 mediastinitis 10.2
18 aortic aneurysm, familial thoracic 8 10.2 FGFR1 ZMYM2
19 miliaria 10.2 NOTCH1 PTPRC
20 tongue squamous cell carcinoma 10.2 MME PTPRC
21 nontoxic goiter 10.1 FGFR1 MYC
22 ovarian wilms' cancer 10.1 MME MYC PTPRC
23 polydactyly cleft lip palate psychomotor retardation 10.1 NOTCH1 PTPRC
24 acute necrotizing encephalopathy 10.1 KMT2A MPO
25 adducted thumbs dundar type 10.0 DNTT KMT2A MPO
26 cd40 ligand deficiency 10.0 PTPRC TAL1
27 hemophagocytic lymphohistiocytosis 10.0 CDKN2B DNTT KMT2A NOTCH1
28 actinobacillosis 10.0 FGFR1 MPO ZMYM2
29 adult acute lymphocytic leukemia 10.0 CDKN2B MME NOTCH1 TAL1
30 desmoid tumor 10.0 DNTT MPO PTPRC
31 amblyopia 10.0 MME MYC NOTCH1 TAL1
32 malignant testicular leydig cell tumor 9.9 CD7 DNTT MPO
33 sarcoma 9.9
34 pulmonary fibrosis, idiopathic 9.9 CDKN2B DNTT MME MYC PTPRC
35 hematopoietic stem cell transplantation 9.9
36 cervicitis 9.9
37 thymoma 9.9
38 histiocytosis 9.9
39 hodgkin's lymphoma, lymphocytic depletion 9.8 MPO PTPRC
40 myeloproliferative neoplasm 9.8
41 bifid uvula 9.8 MYC NOTCH1 TAL1 TRB
42 malignant histiocytosis 9.7
43 myeloid leukemia 9.7
44 myasthenia gravis 9.7
45 bleeding disorder, platelet-type, 18 9.7 DNTT KMT2A MPO MYC PTPRC
46 hyperphosphatasia with mental retardation syndrome 2 9.7 CDKN2B DNTT KMT2A MME MPO MYC
47 cerebritis 9.7
48 intussusception 9.7
49 diffuse large b-cell lymphoma 9.7
50 follicular lymphoma 9.7

Graphical network of the top 20 diseases related to Lymphoblastic Lymphoma:



Diseases related to Lymphoblastic Lymphoma

Symptoms & Phenotypes for Lymphoblastic Lymphoma

GenomeRNAi Phenotypes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.81 FGFR1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.81 DNTT
3 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.81 NOTCH1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.81 DNTT
5 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.81 FGFR1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.81 FGFR1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.81 DNTT NOTCH1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.81 NOTCH1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-151 9.81 DNTT
10 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.81 DNTT
11 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.81 DNTT
12 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.81 NOTCH1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.81 FGFR1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.81 MYC
15 Increased shRNA abundance (Z-score > 2) GR00366-A-182 9.81 DNTT
16 Increased shRNA abundance (Z-score > 2) GR00366-A-183 9.81 FGFR1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-197 9.81 DNTT
18 Increased shRNA abundance (Z-score > 2) GR00366-A-205 9.81 NOTCH1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.81 NOTCH1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.81 MYC
21 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.81 MYC
22 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.81 FGFR1
23 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.81 FGFR1
24 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.81 FGFR1
25 Increased shRNA abundance (Z-score > 2) GR00366-A-6 9.81 NOTCH1
26 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.81 DNTT FGFR1 MYC NOTCH1
27 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.81 FGFR1

MGI Mouse Phenotypes related to Lymphoblastic Lymphoma:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.2 CD7 CDKN2B DNTT FGFR1 FLI1 KMT2A
2 immune system MP:0005387 10.18 CD7 CDKN2B DNTT FGFR1 FLI1 KMT2A
3 homeostasis/metabolism MP:0005376 10.13 CDKN2B DNTT FGFR1 KMT2A MME MPO
4 cardiovascular system MP:0005385 10.1 DNTT FGFR1 FLI1 KMT2A MPO MYC
5 endocrine/exocrine gland MP:0005379 10.02 FLI1 MYC NOTCH1 PTPRC CD7 CDKN2B
6 mortality/aging MP:0010768 9.96 CDKN2B FGFR1 FLI1 KMT2A MPO MYC
7 integument MP:0010771 9.91 CDKN2B FGFR1 KMT2A MME MYC NOTCH1
8 liver/biliary system MP:0005370 9.8 FLI1 KMT2A MME MYC NOTCH1 PTPRC
9 muscle MP:0005369 9.63 FGFR1 FLI1 KMT2A MPO MYC NOTCH1
10 neoplasm MP:0002006 9.43 PTPRC CDKN2B FLI1 KMT2A MYC NOTCH1
11 renal/urinary system MP:0005367 9.1 CDKN2B FGFR1 KMT2A NOTCH1 PTPRC TAL1

Drugs & Therapeutics for Lymphoblastic Lymphoma

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Arranon 17 46 NELARABINE GlaxoSmithKline Approved October 2005

Drugs for Lymphoblastic Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 613)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
2
Cytarabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 147-94-4 6253
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
4
Ifosfamide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 3778-73-2 3690
5
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
6
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1 174722-31-7 10201696
7
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
8
Asparaginase Approved Phase 4,Phase 3,Phase 2,Phase 1 9015-68-3
9
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
10
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
11
Pegaspargase Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 130167-69-0
12
Idarubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 58957-92-9 42890
13
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 135968-09-1
14
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
15
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
16
Cladribine Approved, Investigational Phase 4,Phase 2,Phase 1 4291-63-8 20279
17
Daunorubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 20830-81-3 30323
18
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33419-42-0 36462
19
Fludarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
20
Teniposide Approved Phase 4,Phase 3,Phase 2 29767-20-2 34698
21
Thioguanine Approved Phase 4,Phase 3,Phase 2,Phase 1 154-42-7 2723601
22
Vindesine Approved Phase 4,Phase 3,Phase 2 59917-39-4, 53643-48-4 40839
23
Thiotepa Approved Phase 4,Phase 3,Phase 2,Phase 1 52-24-4 5453
24
Mitoxantrone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 65271-80-9 4212
25
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-23-7 5754 657311
26
Busulfan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 55-98-1 2478
27
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 22916-47-8 4189
28
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
29
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
30
Menthol Approved Phase 4 2216-51-5 16666
31
Blinatumomab Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 853426-35-4
32
Dasatinib Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 302962-49-8 3062316
33
Nicotine Approved Phase 4 54-11-5 942 89594
34
Amphotericin B Approved, Investigational Phase 4,Phase 3,Phase 2 1397-89-3 14956 5280965
35
Micafungin Approved, Investigational Phase 4 235114-32-6 3081921 477468
36
Posaconazole Approved, Investigational, Vet_approved Phase 4 171228-49-2 147912
37
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-30-3 6037
38
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-05-9 54575, 6560146 143
39
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1 31703
40
Butyric Acid Experimental Phase 4,Phase 3,Phase 2,Phase 1 107-92-6 264
41 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
42 Antineoplastic Agents, Alkylating Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
44 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
45 Dexamethasone 21-phosphate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1177-87-3
47 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
48 Isophosphamide mustard Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
49 Antibodies Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
50
Ethylene Phase 4 74-85-1 6325

Interventional clinical trials:

(show top 50) (show all 1629)
id Name Status NCT ID Phase
1 Intensification Therapy of Mature B-ALL, Burkitt and Burkitt Like and Other High Grade Non-Hodgkin's Lymphoma in Adults Unknown status NCT00797810 Phase 4
2 Medical Research Council (MRC) Working Party on Leukaemia in Children UK National Acute Lymphoblastic Leukaemia (ALL) Trial: UKALL 2003 Unknown status NCT00222612 Phase 4
3 Poly(Ethylene Glycol)(PEG)-Asparaginase During Two Treatment Courses Unknown status NCT00192673 Phase 4
4 German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Unknown status NCT00198978 Phase 4
5 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) Unknown status NCT00198991 Phase 4
6 Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia Unknown status NCT01990807 Phase 4
7 German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Completed NCT00199017 Phase 4
8 Trial for the Treatment of Newly Diagnosed Mature B-Cell Acute Lymphoblastic Leukemia (B-ALL), Burkitt's Non-Hodgkin's Lymphoma (NHL) and Other High-grade Lymphoma in Adults Completed NCT00199082 Phase 4
9 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003398 Phase 4
10 ALL-REZ BFM 2002: Multi-Center Study for Children With Relapsed Acute Lymphoblastic Leukemia Completed NCT00114348 Phase 4
11 Pulses of Vincristine and Dexamethasone in BFM Protocols for Children With Acute Lymphoblastic Leukemia Completed NCT00411541 Phase 4
12 Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia Completed NCT01358253 Phase 4
13 LAL-AR-N-2005:Study Treatment for Children High Risk Acute Lymphoblastic Leukemia Completed NCT00526409 Phase 4
14 PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia Completed NCT00494897 Phase 4
15 Intensified Conditioning Regimen With High-Dose-Etoposide for Allo-HSCT for Adult Acute Lymphoblastic Leukemia Completed NCT01457040 Phase 4
16 LAL-BR/2001: Study Treatment to Low Risk ALL Completed NCT00526175 Phase 4
17 Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia Completed NCT00199095 Phase 4
18 Learning Impairments Among Survivors of Childhood Cancer Completed NCT00576472 Phase 4
19 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93) Completed NCT00199069 Phase 4
20 Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab Completed NCT00199004 Phase 4
21 LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive Completed NCT00526305 Phase 4
22 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99) Completed NCT00199056 Phase 4
23 The Study on the Pharmacokinetics of PEG-rhG-CSF in Children and Adolescents Completed NCT02953730 Phase 4
24 ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors Recruiting NCT02938741 Phase 4
25 ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell Tumors Recruiting NCT02290132 Phase 4
26 PETHEMA LAL-07FRAIL: All Treatment In Fragile Patients Ph' Negative Over 55 Years Recruiting NCT01358201 Phase 4
27 ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) Recruiting NCT02670564 Phase 4
28 The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia Recruiting NCT00846703 Phase 4
29 Protocol For the Treatment Acute Lymphoblastic Leukemia With Ph 'Negative in Elderly Patients (> 55 Years) Recruiting NCT01366898 Phase 4
30 Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS Recruiting NCT01540812 Phase 4
31 Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study Recruiting NCT02894645 Phase 4
32 Chemotherapy and Imatinib in Young Adults With Acute Lymphoblastic Leukemia Ph (BCR-ABL) POSITIVE Recruiting NCT01491763 Phase 4
33 Study on Two Different Formulations of 6-mercaptopurine. Tablet Versus Oral Liquid Recruiting NCT01906671 Phase 4
34 HD-Idarubicin/Etoposide Intensified Conditioning Regimen Allo-HSCT for Adult ALL Recruiting NCT01873807 Phase 4
35 Vaccinating Children After Chemotherapy Recruiting NCT02447718 Phase 4
36 Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia Recruiting NCT02618109 Phase 4
37 Treatment of High Risk Adult Acute Lymphoblastic Leukemia Active, not recruiting NCT00853008 Phase 4
38 Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome Active, not recruiting NCT01200355 Phase 4
39 Expanded Access Protocol of Blinatumomab in Pediatric and Adolescent Subjects With Relapsed and/or Refractory B-precursor Acute Lymphoblastic Leukemia (ALL) Available NCT02187354 Phase 4
40 Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients Not yet recruiting NCT02690922 Phase 4
41 G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor Not yet recruiting NCT02933333 Phase 4
42 A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT Not yet recruiting NCT03176849 Phase 4
43 ProphyALL - Study on the Safety of Liposomal Amphotericin B to Prevent Antifungal Infections in Elderly Patients With Acute Lymphoblastic Leukemia Terminated NCT00386997 Phase 4
44 Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma Unknown status NCT00003650 Phase 3
45 Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma Unknown status NCT00003728 Phase 3
46 Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma Unknown status NCT00003423 Phase 3
47 Radiolabeled Monoclonal Antibody in the Detection and Staging of Patients With Non-Hodgkin's Lymphoma Unknown status NCT00003337 Phase 3
48 Monoclonal Antibodies in Detecting Residual Disease in Patients Who Have Been Treated for Non-Hodgkin's Lymphoma Unknown status NCT00003338 Phase 2, Phase 3
49 Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma Unknown status NCT00003815 Phase 3
50 Combination Chemotherapy With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma Unknown status NCT00052936 Phase 3

Search NIH Clinical Center for Lymphoblastic Lymphoma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Lymphoblastic Lymphoma cell therapies at LifeMap Discovery.

Genetic Tests for Lymphoblastic Lymphoma

Anatomical Context for Lymphoblastic Lymphoma

MalaCards organs/tissues related to Lymphoblastic Lymphoma:

39
T Cells, B Cells, Bone, B Lymphoblasts, Lymph Node, Bone Marrow, Myeloid

The Foundational Model of Anatomy Ontology organs/tissues related to Lymphoblastic Lymphoma:

18
Primarily Lymph Nodes Or

Publications for Lymphoblastic Lymphoma

Articles related to Lymphoblastic Lymphoma:

(show top 50) (show all 589)
id Title Authors Year
1
Mathematical model of T-cell lymphoblastic lymphoma: disease, treatment, cure or relapse of a virtual cohort of patients. ( 28082512 )
2017
2
Synchronous T lymphoblastic lymphoma and myeloid neoplasm with PDGFRA rearrangement. ( 28013529 )
2017
3
Ecthyma gangrenosum in a case of acute lymphoblastic lymphoma. ( 28052953 )
2017
4
Relapsed or Refractory Lymphoblastic Lymphoma in Children: Results and Analysis of 23 Patients in the EORTC 58951 and the LMT96 Protocols. ( 27037853 )
2016
5
Lymphoblastic lymphoma with a triple hit profile: a rare but distinct and relevant entity. ( 27867103 )
2016
6
Outcome of children and adolescents with lymphoblastic lymphoma. ( 27008495 )
2016
7
A childhood chemotherapy protocol improves overall survival among adults with T-lymphoblastic lymphoma. ( 27150061 )
2016
8
Primary T-cell lymphoblastic lymphoma in the middle ear. ( 26857309 )
2016
9
Clinical Outcomes after Allogeneic Stem Cell Transplantation for Adult Lymphoblastic Lymphoma. ( 27334855 )
2016
10
Genomic characterization of pediatric B-lymphoblastic lymphoma and B-lymphoblastic leukemia using formalin-fixed tissues. ( 27957801 )
2016
11
Lymphoblastic lymphoma presenting as bilateral renal enlargement diagnosed by percutaneous kidney biopsy: Report of three cases. ( 27512306 )
2016
12
Lymphoblastic lymphoma: an updated review on biology, diagnosis, and treatment. ( 26679753 )
2016
13
Deletion of Pten in CD45-expressing cells leads to development of T-cell lymphoblastic lymphoma but not myeloid malignancies. ( 26773036 )
2016
14
Primary orbital precursor T-cell lymphoblastic lymphoma: Report of a unique case. ( 27900092 )
2016
15
When to Treat Adults Like Children: Optimizing Therapy for Lymphoblastic Lymphoma in Young Adults. ( 26700121 )
2016
16
Precursor B-Cell Lymphoblastic Lymphoma Presenting as a Spinal Mass at Initial Diagnosis. ( 27094224 )
2016
17
Precursor B-cell lymphoblastic lymphoma of oral cavity: A case report with its diagnostic workup. ( 27194876 )
2016
18
Myeloproliferative neoplasm with eosinophilia and T-lymphoblastic lymphoma with ETV6-LYN gene fusion. ( 27058227 )
2016
19
Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma. ( 27556297 )
2016
20
Successful use of extracorporeal membrane oxygenation during induction chemotherapy in a patient with mediastinal tumor mass of a T lymphoblastic lymphoma. ( 27324259 )
2016
21
Results of treatment of lymphoblastic lymphoma at the children cancer hospital Egypt - A single center experience. ( 27339800 )
2016
22
Prognostic Impact of Intensified Maintenance Therapy on Children With Advanced Lymphoblastic Lymphoma: A Report From the Japanese Pediatric Leukemia/Lymphoma Study Group ALB-NHL03 Study. ( 26585702 )
2016
23
Effects of microRNA-21 on the biological functions of T-cell acute lymphoblastic lymphoma/leukemia. ( 27895788 )
2016
24
Pediatric-Like Acute Lymphoblastic Leukemia Therapy in Adults With Lymphoblastic Lymphoma: The GRAALL-LYSA LL03 Study. ( 26644537 )
2016
25
Primary Testicular Pre-B Lymphoblastic Lymphoma. ( 27170920 )
2016
26
Imaging findings of childhood B-cell lymphoblastic lymphoma in the mental region: a case report. ( 27936917 )
2016
27
Precursor B cell lymphoblastic lymphoma presenting as periorbital swelling. ( 27166006 )
2016
28
Characteristics and outcomes of lymphoblastic lymphoma - the University of Miami experience. ( 27252116 )
2016
29
Stem cell transplantation outcomes in lymphoblastic lymphoma. ( 27348707 )
2016
30
Terminal deoxynucleotidyl transferase (TDT)-negative t-cell lymphoblastic lymphoma does exist: A case report. ( 27772900 )
2016
31
Fluorine-18 fluorodeoxyglucose positron emission tomography imaging of T-lymphoblastic lymphoma patients. ( 27446482 )
2016
32
Metachronous T-Lymphoblastic Lymphoma and Burkitt Lymphoma in a Child With Constitutional Mismatch Repair Deficiency Syndrome. ( 27037742 )
2016
33
Lymphoblastic Lymphoma Presenting as Bilateral Ovarian Mass in an Adolescent Girl. ( 27965123 )
2016
34
Lineage switch with t(6;11)(q27;q23) from T-cell lymphoblastic lymphoma to acute monoblastic leukemia at relapse. ( 27268298 )
2016
35
Current status and future directions of T-lymphoblastic lymphoma in children and adolescents. ( 26991119 )
2016
36
Immune Thrombocytopenia in a Child with T Cell Lymphoblastic Lymphoma. ( 27668103 )
2016
37
Retinoid-related orphan receptor I^ (RORI^) adult induced knockout mice develop lymphoblastic lymphoma. ( 27491564 )
2016
38
A T cell lymphoblastic lymphoma with mucormycosis as unusual etiology of acute cerebral ischemia. ( 26666534 )
2016
39
Serum level of soluble interleukin-2 receptor correlates with CD25 expression in patients with T lymphoblastic lymphoma. ( 25935549 )
2015
40
T-lymphoblastic lymphoma with cutaneous involvement. ( 26301233 )
2015
41
Treatment of Childhood T-Cell Lymphoblastic Lymphoma-Long-Term Results of the SFOP LMT96 Trial. ( 26248696 )
2015
42
Bilateral Ovarian B-Lineage Lymphoblastic Lymphoma With MLL Gene Rearrangement: A Novel Case in Infancy. ( 25493458 )
2015
43
Cerebral venous thrombosis in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma during induction chemotherapy with l-asparaginase: The GRAALL experience. ( 26214580 )
2015
44
A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. ( 26407235 )
2015
45
Outcomes of dose-adjusted Berlin-Frankfurt-MA1nster-90 regimen without radiotherapy in adolescents and adults with T cell lymphoblastic lymphoma. ( 25752875 )
2015
46
Upregulation of miRNA-17 and miRNA-19 is associated with unfavorable prognosis in patients with T-cell lymphoblastic lymphoma. ( 26231295 )
2015
47
NOTCH1 Intracellular Domain Immunohistochemistry as a Diagnostic Tool to Distinguish T-Lymphoblastic Lymphoma From Thymoma. ( 25517959 )
2015
48
Primary testicular Ph-positive B lymphoblastic lymphoma: an unusual presentation and review. ( 26147907 )
2015
49
Long-term results of the AIEOP LNH-97 protocol for childhood lymphoblastic lymphoma. ( 25755200 )
2015
50
Multicenter analysis of treatment outcomes in adult patients with lymphoblastic lymphoma who received hyper-CVAD induction followed by hematopoietic stem cell transplantation. ( 25465233 )
2015

Variations for Lymphoblastic Lymphoma

Expression for Lymphoblastic Lymphoma

Search GEO for disease gene expression data for Lymphoblastic Lymphoma.

Pathways for Lymphoblastic Lymphoma

GO Terms for Lymphoblastic Lymphoma

Biological processes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription from RNA polymerase II promoter GO:0045944 9.73 CDKN2B FLI1 KMT2A MYC NOTCH1 TAL1
2 regulation of transcription from RNA polymerase II promoter GO:0006357 9.55 FLI1 MYC NOTCH1 TAL1 ZMYM2
3 positive regulation of mesenchymal cell proliferation GO:0002053 9.48 FGFR1 MYC
4 positive regulation of cardiac muscle cell proliferation GO:0060045 9.46 FGFR1 NOTCH1
5 megakaryocyte development GO:0035855 9.43 FLI1 TAL1
6 definitive hemopoiesis GO:0060216 9.4 KMT2A TAL1
7 embryonic hemopoiesis GO:0035162 9.37 KMT2A TAL1
8 generation of neurons GO:0048699 9.32 FGFR1 TAL1
9 megakaryocyte differentiation GO:0030219 8.96 CDKN2B TAL1
10 regulation of gene expression GO:0010468 8.92 FGFR1 KMT2A MYC NOTCH1

Molecular functions related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.02 FLI1 KMT2A MPO NOTCH1 TAL1

Sources for Lymphoblastic Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....