MCID: LYM040
MIFTS: 58

Lymphoblastic Lymphoma

Categories: Rare diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Lymphoblastic Lymphoma

MalaCards integrated aliases for Lymphoblastic Lymphoma:

Name: Lymphoblastic Lymphoma 37 12 72 49 14
Precursor Cell Lymphoblastic Leukemia Lymphoma 69
Precursor Cell Lymphoblastic Lymphoma 69
Lymphoma, Lymphoblastic 49
Lymphoma Lymphoblastic 51

Classifications:



External Ids:

Disease Ontology 12 DOID:0080147
ICD10 32 C83.5

Summaries for Lymphoblastic Lymphoma

Disease Ontology : 12 A lymphoma that has material basis in immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage and located in primarily lymph nodes or located in extranodal sites.

MalaCards based summary : Lymphoblastic Lymphoma, also known as precursor cell lymphoblastic leukemia lymphoma, is related to leukemia and lymphosarcoma. An important gene associated with Lymphoblastic Lymphoma is ZMYM2 (Zinc Finger MYM-Type Containing 2), and among its related pathways/superpathways are NF-kappaB Signaling and Transcriptional misregulation in cancer. The drugs Arranon and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include primarily lymph nodes or, bone and t cells, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the... more...

Related Diseases for Lymphoblastic Lymphoma

Diseases related to Lymphoblastic Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 162)
# Related Disease Score Top Affiliating Genes
1 leukemia 30.2 FLI1 KMT2A MME TAL1
2 lymphosarcoma 29.6 BCL6 PTPRC
3 acute biphenotypic leukemia 29.6 DNTT KMT2A MPO
4 thymoma 29.6 CD5 DNTT PTPRC
5 acute leukemia 29.4 DNTT KMT2A MPO TAL1
6 8p11 myeloproliferative syndrome 29.4 FGFR1 ZMYM2
7 acute lymphocytic leukemia 29.3 CDKN2B MME NOTCH1 TAL1
8 dendritic cell tumor 29.3 DNTT MPO PTPRC
9 myeloid sarcoma 29.2 DNTT KMT2A MPO PTPRC
10 diffuse large b-cell lymphoma 29.1 BCL6 CD5 MME
11 follicular lymphoma 29.0 BCL6 CD5 MME
12 b-cell lymphomas 29.0 BCL6 CD5 MME
13 mantle cell lymphoma 28.8 BCL6 CD5 MME
14 ewing sarcoma 28.7 DNTT FGFR1 FLI1 PTPRC
15 leukemia, chronic lymphocytic 28.4 BCL6 CD5 DNTT NOTCH1 PTPRC
16 lymphoma, non-hodgkin, familial 28.1 BCL6 CD5 CDKN2B DNTT MME PTPRC
17 precursor t-cell acute lymphoblastic leukemia 27.9 CDKN2B DNTT KMT2A MPO NOTCH1 TAL1
18 leukemia, acute myeloid 27.0 CD5 CDKN2B DNTT KMT2A MME MPO
19 t-cell childhood lymphoblastic lymphoma 12.3
20 precursor t-lymphoblastic lymphoma/leukemia 12.2
21 precursor b lymphoblastic lymphoma/leukemia 12.1
22 precursor lymphoblastic lymphoma/leukemia 12.0
23 childhood precursor t-lymphoblastic lymphoma/leukemia 12.0
24 precursor t-lymphoblastic lymphoma/leukemia refractory 12.0
25 chromosome 8p11 myeloproliferative syndrome 11.1
26 acute t cell leukemia 11.0
27 lymphoma 11.0
28 lymphoblastic leukemia 10.4
29 myasthenic syndrome, congenital, 6, presynaptic 10.4 FGFR1 ZMYM2
30 chromosomal triplication 10.3 BCL6 KMT2A
31 nodular lymphocyte predominant hodgkin lymphoma 10.3 BCL6 PTPRC
32 photokeratitis 10.3 DNTT PTPRC
33 immunodeficiency 18 10.3 PTPRC TAL1
34 gallbladder lymphoma 10.3 BCL6 MME
35 mediastinitis 10.3
36 ovarian lymphoma 10.2 MME PTPRC
37 angioimmunoblastic t-cell lymphoma 10.2 BCL6 MME
38 t-cell/histiocyte rich large b cell lymphoma 10.2 BCL6 MME
39 plasmablastic lymphoma 10.2 BCL6 NOTCH1 PTPRC
40 ewing's family of tumors 10.2 CDKN2B FLI1
41 extraskeletal ewing sarcoma 10.1 FLI1 PTPRC
42 chronic monocytic leukemia 10.1 MPO PTPRC
43 bone marrow cancer 10.1 FGFR1 MPO ZMYM2
44 heart lymphoma 10.0 BCL6 MME PTPRC
45 testicular lymphoma 10.0 BCL6 MME PTPRC
46 acute erythroid leukemia 10.0 FLI1 TAL1
47 hematologic cancer 10.0 CDKN2B DNTT KMT2A NOTCH1
48 mature b-cell neoplasm 10.0 BCL6 MME PTPRC
49 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 10.0 DNTT KMT2A MPO
50 sarcoma 10.0

Graphical network of the top 20 diseases related to Lymphoblastic Lymphoma:



Diseases related to Lymphoblastic Lymphoma

Symptoms & Phenotypes for Lymphoblastic Lymphoma

MGI Mouse Phenotypes related to Lymphoblastic Lymphoma:

43 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.22 BCL6 CD5 CDKN2B DNTT FGFR1 FLI1
2 immune system MP:0005387 10.21 CD5 CDKN2B DNTT FGFR1 FLI1 KMT2A
3 homeostasis/metabolism MP:0005376 10.16 MPO NOTCH1 PTPRC TAL1 BCL6 CDKN2B
4 cardiovascular system MP:0005385 10.1 BCL6 DNTT FGFR1 FLI1 KMT2A MPO
5 mortality/aging MP:0010768 10.02 BCL6 CDKN2B FGFR1 FLI1 KMT2A MPO
6 integument MP:0010771 9.95 TAL1 CD5 CDKN2B FGFR1 KMT2A MME
7 liver/biliary system MP:0005370 9.85 BCL6 FLI1 KMT2A MME NOTCH1 PTPRC
8 muscle MP:0005369 9.73 BCL6 FGFR1 FLI1 KMT2A MPO NOTCH1
9 no phenotypic analysis MP:0003012 9.63 KMT2A PTPRC BCL6 CD5 CDKN2B FGFR1
10 normal MP:0002873 9.5 BCL6 CD5 DNTT FGFR1 KMT2A NOTCH1
11 renal/urinary system MP:0005367 9.1 CDKN2B FGFR1 KMT2A NOTCH1 PTPRC TAL1

Drugs & Therapeutics for Lymphoblastic Lymphoma

FDA approved drugs:

# Drug Name Active Ingredient(s) 17 Company Approval Date
1
Arranon 17 45 NELARABINE GlaxoSmithKline October 2005

Drugs for Lymphoblastic Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 492)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
2
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33419-42-0 36462
3
Teniposide Approved Phase 4,Phase 2 29767-20-2 34698
4
Asparaginase Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9015-68-3
5
Cladribine Approved, Investigational Phase 4,Phase 2,Phase 1 4291-63-8 20279
6
Cytarabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 147-94-4 6253
7
Daunorubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 20830-81-3 30323
8
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
9
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 23214-92-8 31703
10
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1959-05-2, 59-05-2 126941
11
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
12
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
13
Thioguanine Approved Phase 4,Phase 3,Phase 2,Phase 1 154-42-7 2723601
14
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2068-78-2, 57-22-7 5978
15
Vindesine Approved, Investigational Phase 4,Phase 3,Phase 2 53643-48-4, 59917-39-4 40839
16
Ifosfamide Approved Phase 4,Phase 2,Phase 3,Phase 1 3778-73-2 3690
17
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 174722-31-7 10201696
18
Lenograstim Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
19 Thiotepa Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 52-24-4 5453
20
Busulfan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 55-98-1 2478
21
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-30-3 6037
22
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-05-9 143 6006
23
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 31703
24 Antilymphocyte Serum Phase 4,Phase 2,Phase 3,Phase 1
25 Etoposide phosphate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
26 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 6-Mercaptopurine Phase 4,Phase 3,Phase 2,Phase 1
28 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
29 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
30 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
31 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1
32 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
33 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Antimetabolites Phase 4,Phase 3,Phase 2,Phase 1
35 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 2,Phase 1
36 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
37 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1
38 Antineoplastic Agents, Phytogenic Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
42 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
44 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1177-87-3
45 Folic Acid Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
47 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
48 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
49 Hormones Phase 4,Phase 3,Phase 2,Phase 1
50 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 648)

# Name Status NCT ID Phase Drugs
1 ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell Tumors Unknown status NCT02290132 Phase 4 Rabbit Anti-human Thymocyte Globulin (ATG)
2 German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Completed NCT00199017 Phase 4 Dexamethasone/Prednisolone;Cyclophosphamide;Vincristine;Daunorubicin;Asparaginase;G-CSF;Mercaptopurine;Cytarabine;Methotrexate;VP16;Vindesine;Adriamycin;Thioguanine;HDARAC;Cladribine
3 Trial for the Treatment of Newly Diagnosed Mature B-Cell Acute Lymphoblastic Leukemia (B-ALL), Burkitt's Non-Hodgkin's Lymphoma (NHL) and Other High-grade Lymphoma in Adults Completed NCT00199082 Phase 4 Adriamycin;Cyclophosphamide;Cytarabine;Dexamethasone/Prednisolone;VP16;Ifosfamide;Methotrexate;G-CSF;Rituximab;Vincristine/Vindesine
4 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003398 Phase 4 cyclophosphamide;thiotepa
5 ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors Recruiting NCT02938741 Phase 4 Anti-human Thymoglobulin;Placebo
6 Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma Unknown status NCT00003650 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;mercaptopurine;methotrexate;methylprednisolone;mitoxantrone hydrochloride;prednisone;vincristine sulfate
7 Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain Unknown status NCT01316744 Phase 3 ketamine hydrochloride
8 Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia Unknown status NCT00445497 Phase 3 amoxicillin-clavulanate potassium;ciprofloxacin
9 Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma Unknown status NCT00003423 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;etoposide;mercaptopurine;methotrexate;prednisolone;thioguanine;vincristine sulfate
10 Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma Unknown status NCT00003728 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;etoposide;leucovorin calcium;mercaptopurine;methotrexate;methylprednisolone;mitoxantrone hydrochloride;prednisolone;therapeutic hydrocortisone;thioguanine;vincristine sulfate;vindesine
11 Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia Unknown status NCT00020865 Phase 3 cefepime hydrochloride;levofloxacin
12 Monoclonal Antibodies in Detecting Residual Disease in Patients Who Have Been Treated for Non-Hodgkin's Lymphoma Unknown status NCT00003338 Phase 2, Phase 3
13 Radiolabeled Monoclonal Antibody in the Detection and Staging of Patients With Non-Hodgkin's Lymphoma Unknown status NCT00003337 Phase 3
14 Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome Unknown status NCT00002989 Phase 3 busulfan;cyclophosphamide;idarubicin;melphalan
15 Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma Unknown status NCT00003815 Phase 3 carmustine;cyclophosphamide;cytarabine;doxorubicin hydrochloride;etoposide;melphalan;prednisolone;vincristine sulfate
16 Combination Chemotherapy Followed By Radiation Therapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma Unknown status NCT00053768 Phase 3 EPOCH regimen;cyclophosphamide;doxorubicin hydrochloride;etoposide;prednisone;vincristine sulfate
17 Combination Chemotherapy With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma Unknown status NCT00052936 Phase 3 CHOP regimen;cyclophosphamide;doxorubicin hydrochloride;prednisone;vincristine sulfate
18 Interferon Alfa-2b Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Hodgkin's Disease or Non-Hodgkin's Lymphoma Unknown status NCT00003924 Phase 3
19 Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma Completed NCT00003187 Phase 2, Phase 3 cyclophosphamide;cyclosporine;cytarabine;methotrexate;methylprednisolone
20 A Study of Actonel for the Prevention of Bone Loss Completed NCT00452439 Phase 3 Actonel (Risedronate)
21 Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma Completed NCT00002766 Phase 3 carmustine;cyclophosphamide;cytarabine;daunorubicin hydrochloride;doxorubicin hydrochloride;etoposide;mercaptopurine;methotrexate;mitoxantrone hydrochloride;pegaspargase;prednisone;vincristine sulfate
22 Study of Treatment High Risk and/or Low Risk Acute Lymphoblastic leukémia(ALL) Adults Stage III Completed NCT00483132 Phase 3 interferon alpha 2a
23 Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications Completed NCT00799461 Phase 3
24 Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma Completed NCT01230983 Phase 3 asparaginase;cytarabine;dexrazoxane hydrochloride;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;prednisone;therapeutic hydrocortisone;vincristine sulfate
25 Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia Completed NCT00002700 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;mitoxantrone hydrochloride;prednisolone;prednisone;therapeutic hydrocortisone;vincristine sulfate
26 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
27 American Ginseng in Treating Patients With Fatigue Caused by Cancer Completed NCT00719563 Phase 3 American ginseng
28 Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain Completed NCT00666211 Phase 3
29 Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer Completed NCT00661999 Phase 3 sodium ferric gluconate complex in sucrose
30 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
31 Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count Completed NCT00003805 Phase 3 piperacillin sodium;piperacillin-tazobactam;tazobactam sodium;vancomycin
32 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
33 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
34 Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer Completed NCT00265837 Phase 3
35 St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer Completed NCT00005805 Phase 3
36 Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter Completed NCT00006083 Phase 3 Fragmin
37 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
38 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
39 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
40 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
41 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3 levofloxacin
42 Combination Chemotherapy in Treating Older Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma Completed NCT00002576 Phase 3 cyclophosphamide;doxorubicin hydrochloride;mitoxantrone hydrochloride;prednisolone;vincristine sulfate
43 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
44 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3 ondansetron
45 Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer Completed NCT00369564 Phase 3 glutamic acid
46 Sibling Donor Peripheral Stem Cell Transplant or Sibling Donor Bone Marrow Transplant in Treating Patients With Hematologic Cancers or Other Diseases Completed NCT00438958 Phase 3
47 Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer Completed NCT00053053 Phase 3
48 Treatment for Chronic Pain in Patients With Advanced Cancer Completed NCT00003687 Phase 3 dextromethorphan hydrobromide;morphine sulfate
49 Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorder Completed NCT00755040 Phase 3 cyclosporine ophthalmic emulsion
50 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3 supersaturated calcium phosphate rinse

Search NIH Clinical Center for Lymphoblastic Lymphoma

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Lymphoblastic Lymphoma cell therapies at LifeMap Discovery.

Genetic Tests for Lymphoblastic Lymphoma

Anatomical Context for Lymphoblastic Lymphoma

The Foundational Model of Anatomy Ontology organs/tissues related to Lymphoblastic Lymphoma:

18
Primarily Lymph Nodes Or

MalaCards organs/tissues related to Lymphoblastic Lymphoma:

38
Bone, T Cells, Bone Marrow, B Cells, Lymph Node, Kidney, Liver

Publications for Lymphoblastic Lymphoma

Articles related to Lymphoblastic Lymphoma:

(show top 50) (show all 629)
# Title Authors Year
1
Outcome of pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma with hypersensitivity to pegaspargase treated with PEGylated Erwinia asparaginase, pegcrisantaspase: A report from the Children's Oncology Group. ( 29090524 )
2018
2
Hyper-CVAD plus nelarabine in newly diagnosed adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma. ( 29047158 )
2018
3
Patients over 40 years old with precursor T-cell lymphoblastic lymphoma have different prognostic factors comparing to the youngers. ( 29348421 )
2018
4
Pediatric Patient With T-Cell Lymphoblastic Lymphoma and Acute Vision Loss. ( 29121170 )
2018
5
Lymphoblastic Lymphoma Involving Multiple Vertebrae. ( 28962960 )
2018
6
Acute lymphoblastic leukemia and lymphoblastic lymphoma in adolescents and young adults. ( 29418064 )
2018
7
The inhibitory effect of MEG3/miR-214/AIFM2 axis on the growth of T-cell lymphoblastic lymphoma. ( 28534937 )
2017
8
Clinical impact of miR-223 expression in pediatric T-Cell lymphoblastic lymphoma. ( 29296210 )
2017
9
Results and conclusions of the European Intergroup EURO-LB02 trial in children and adolescents with lymphoblastic lymphoma. ( 28983060 )
2017
10
An Unsuspected Finding of t(9;22): A Rare Case of Philadelphia Chromosome-Positive B-Lymphoblastic Lymphoma. ( 29075538 )
2017
11
Bcl-2 maturation pattern in T-cells distinguishes thymic neoplasm/hyperplasia, T-lymphoblastic lymphoma, and reactive lymph nodes. ( 28718205 )
2017
12
Myeloid Neoplasia and Lymphoblastic Lymphoma with Eosinophilia After RAI: A Case Report. ( 28958974 )
2017
13
Synchronous T lymphoblastic lymphoma and myeloid neoplasm with PDGFRA rearrangement. ( 28013529 )
2017
14
Adult T-type lymphoblastic lymphoma: Treatment advances and prognostic indicators. ( 28412288 )
2017
15
Ecthyma gangrenosum in a case of acute lymphoblastic lymphoma. ( 28052953 )
2017
16
FGFR1 translocation with concurrent myeloproliferative neoplasm, systemic mastocytosis, and lymphoblastic lymphoma: a case report. ( 29107667 )
2017
17
Primary T-cell Lymphoblastic Lymphoma of the Ovary: A Case Report. ( 28469345 )
2017
18
A Case of Cutaneous Involvement in T Lymphoblastic Lymphoma Leukemia. ( 28879704 )
2017
19
Prognostic Factors and Outcomes of Adult Lymphoblastic Lymphoma in the United States. ( 28647403 )
2017
20
JSH guideline for tumors of hematopoietic and lymphoid tissues-leukemia: 3. Acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL). ( 29067593 )
2017
21
Mathematical model of T-cell lymphoblastic lymphoma: disease, treatment, cure or relapse of a virtual cohort of patients. ( 28082512 )
2017
22
Safety and efficacy of nelarabine in children and young adults with relapsed or refractory T-lineage acute lymphoblastic leukaemia or T-lineage lymphoblastic lymphoma: results of a phase 4 study. ( 28771663 )
2017
23
Successful Treatment of Mediastinal I^I' T-Cell Lymphoblastic Lymphoma in a 3-Year-Old Girl by Allogeneic Cord Blood Transplantation. ( 29200146 )
2017
24
T cell lymphoblastic lymphoma/leukemia within an adrenocorticotropic hormone and thyroid stimulating hormone positive pituitary adenoma: A cytohistological correlation emphasizing importance of intra-operative squash smear. ( 28295636 )
2017
25
Indolent T-lymphoblastic proliferation concomitant with acinic cell carcinoma mimicking T-lymphoblastic lymphoma: case report and literature review. ( 29143359 )
2017
26
B-cell lymphoblastic lymphoma presenting as solitary temporal mass with amplification of AML1/RUNX1: case report. ( 28933515 )
2017
27
Clinical characteristics and outcomes of previously untreated patients with adult onset T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma with hyper-CVAD based regimens. ( 28646517 )
2017
28
Philadelphia chromosome-positive B-lymphoblastic lymphoma involving the genitourinary system and bone at initial diagnosis and relapse. ( 28935645 )
2017
29
Primary Cutaneous B-Cell Lymphoblastic Lymphoma Arising from a Long-Standing Lesion in a Child and Review of the Literature. ( 28547875 )
2017
30
Clinical Features and Prognosis According to Immunophenotypic Subtypes Including the Early T-Cell Precursor Subtype of T-Lymphoblastic Lymphoma in the Japanese Pediatric Leukemia/Lymphoma Study Group ALB-NHL03 Study. ( 28538509 )
2017
31
Predictive value of (18)F-FDG PET/CT in adults with T-cell lymphoblastic lymphoma: post hoc analysis of results from the GRAALL-LYSA LLO3 trial. ( 28733763 )
2017
32
Lymphoblastic lymphoma of the palate. ( 28966460 )
2017
33
Fibroblast growth factor receptor-1 associated myeloproliferative neoplasm and T-lymphoblastic lymphoma. ( 29323084 )
2017
34
PEG-asparaginase in BFM-90 regimen improves outcomes in adults with newly diagnosed lymphoblastic lymphoma. ( 28373755 )
2017
35
Immunophenotypic analysis of adult patients with T-cell lymphoblastic lymphoma treated with hyper-CVAD. ( 28778131 )
2017
36
Case Report: A Cryptosporidium infection in a patient with relapsed T-lymphoblastic lymphoma undergoing allogeneic stem cell transplantation. ( 29140544 )
2017
37
Image Gallery: Primary cutaneous precursor B-lymphoblastic lymphoma in an infant. ( 29313927 )
2017
38
B-lymphoblastic lymphoma of the rectum. ( 28670078 )
2017
39
Lymphoblastic lymphoma. ( 28427520 )
2017
40
Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma. ( 28827401 )
2017
41
T cell acute lymphoblastic lymphoma complicated with myeloid sarcoma in an adult: A case report. ( 29344261 )
2017
42
Successful use of extracorporeal membrane oxygenation during induction chemotherapy in a patient with mediastinal tumor mass of a T lymphoblastic lymphoma. ( 27324259 )
2016
43
Current status and future directions of T-lymphoblastic lymphoma in children and adolescents. ( 26991119 )
2016
44
A T cell lymphoblastic lymphoma with mucormycosis as unusual etiology of acute cerebral ischemia. ( 26666534 )
2016
45
Lymphoblastic Lymphoma Presenting as Bilateral Ovarian Mass in an Adolescent Girl. ( 27965123 )
2016
46
Immune Thrombocytopenia in a Child with T Cell Lymphoblastic Lymphoma. ( 27668103 )
2016
47
Effects of microRNA-21 on the biological functions of T-cell acute lymphoblastic lymphoma/leukemia. ( 27895788 )
2016
48
Terminal deoxynucleotidyl transferase (TDT)-negative t-cell lymphoblastic lymphoma does exist: A case report. ( 27772900 )
2016
49
Primary orbital precursor T-cell lymphoblastic lymphoma: Report of a unique case. ( 27900092 )
2016
50
Characteristics and outcomes of lymphoblastic lymphoma - the University of Miami experience. ( 27252116 )
2016

Variations for Lymphoblastic Lymphoma

Expression for Lymphoblastic Lymphoma

Search GEO for disease gene expression data for Lymphoblastic Lymphoma.

Pathways for Lymphoblastic Lymphoma

GO Terms for Lymphoblastic Lymphoma

Biological processes related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.73 BCL6 CDKN2B KMT2A NOTCH1
2 regulation of transcription by RNA polymerase II GO:0006357 9.55 BCL6 FLI1 NOTCH1 TAL1 ZMYM2
3 definitive hemopoiesis GO:0060216 9.4 KMT2A TAL1
4 megakaryocyte development GO:0035855 9.37 FLI1 TAL1
5 embryonic hemopoiesis GO:0035162 9.32 KMT2A TAL1
6 generation of neurons GO:0048699 9.26 FGFR1 TAL1
7 regulation of cell proliferation GO:0042127 9.26 BCL6 FGFR1 NOTCH1 TAL1
8 megakaryocyte differentiation GO:0030219 8.62 CDKN2B TAL1

Molecular functions related to Lymphoblastic Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.1 BCL6 FLI1 KMT2A MPO NOTCH1 TAL1

Sources for Lymphoblastic Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
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16 ExPASy
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67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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